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Dipòsit Digital de la Universitat de Barcelona: Endoscopic ultrasound-guided biliary rendezvous after failed cannulation, and comparison between benign vs malignant biliopancreatic disorders: outcomes at a single tertiary-care centre
<!DOCTYPE html> <html> <head> <title>Dipòsit Digital de la Universitat de Barcelona: Endoscopic ultrasound-guided biliary rendezvous after failed cannulation, and comparison between benign vs malignant biliopancreatic disorders: outcomes at a single tertiary-care centre</title> <base href="https://diposit.ub.edu" /> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8" /> <meta name="Generator" content="DSpace 5.8" /> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link rel="shortcut icon" href="/dspace/favicon.ico" type="image/x-icon"/> <link rel="stylesheet" href="/dspace/static/css/jquery-ui-1.10.3.custom/redmond/jquery-ui-1.10.3.custom.css" type="text/css" /> <link rel="stylesheet" href="/dspace/static/css/bootstrap/bootstrap.min.css" type="text/css" /> <link rel="stylesheet" href="/dspace/static/css/bootstrap/bootstrap-theme.min.css" type="text/css" /> <link rel="stylesheet" href="/dspace/static/css/bootstrap/dspace-theme.css" type="text/css" /> <link rel="search" type="application/opensearchdescription+xml" href="/dspace/open-search/description.xml" title="DSpace"/> <link rel="schema.DCTERMS" href="http://purl.org/dc/terms/" /> <link rel="schema.DC" href="http://purl.org/dc/elements/1.1/" /> <meta name="DC.creator" content="Gornals Soler, Joan B." /> <meta name="DC.creator" content="Sumalla-Garcia, Albert" /> <meta name="DC.creator" content="Quintana, Sergi" /> <meta name="DC.creator" content="Luna-Rodriguez, Daniel" /> <meta name="DC.creator" content="Velasquez Rodriguez, Julio G." /> <meta name="DC.creator" content="Puigcerver-Mas, Maria" /> <meta name="DC.creator" content="Escuer-Turu, Julia" /> <meta name="DC.creator" content="Maisterra, Sandra" /> <meta name="DC.creator" content="Marin, Mar" /> <meta name="DC.creator" content="Munoa, Virginia" /> <meta name="DC.creator" content="Laquente, Berta" /> <meta name="DC.creator" content="Busquets Barenys, Juli" /> <meta name="DCTERMS.dateAccepted" content="2024-11-14T16:54:43Z" scheme="DCTERMS.W3CDTF" /> <meta name="DCTERMS.available" content="2024-11-14T16:54:43Z" scheme="DCTERMS.W3CDTF" /> <meta name="DCTERMS.issued" content="2024-12-01" scheme="DCTERMS.W3CDTF" /> <meta name="DC.identifier" content="0785-3890" /> <meta name="DC.identifier" content="https://hdl.handle.net/2445/216492" scheme="DCTERMS.URI" /> <meta name="DCTERMS.abstract" content="Background: Endoscopic ultrasound (EUS)-guided biliary rendezvous (RV) is an EUS-assisted technique described as a rescue method in cases of failed biliary cannulation via endoscopic retrograde cholangiography (ERC). Current literature remains unclear regarding its current role. The study aim was to evaluate the effectiveness for biliary EUS-RV, and comparison between benign vs malignant biliopancreatic disorders. Methods: Retrospective observational study with prospective consecutive inclusion in a specific database from a tertiary-center. All patients with biliopancreatic diseases that underwent a EUS-assisted ERC between October-2010 and November-2022 for failed ERC were included. Main outcomes were technical/overall success. Secondary outcomes were safety, potential factors related to failure/success or safety; and a comparative analysis between EUS-RV and EUS-guided transmural drainage (TMD) in malignant cases. Results: A total of 69 patients who underwent EUS-RV procedures, with benign and malignant pathologies (n = 40 vs n = 29), were included. Technical / overall success and related-adverse events (AEs) were 79.7% (95%CI, 68.3-88.4) / 74% (95%CI, 61-83.7) and 24% (95%CI, 15.1-36.5), respectively. Failed cases were mainly related with guidewire manipulation. Seven failed RV were successfully rescued by EUS-TMD. On multivariable analysis, EUS-RV and malignant pathology was associated with a greater failure rate (technical success: OR,0.21; 95%CI,0.05-0.72; p = 0.017), and higher AEs rate (OR,3.46; 95%CI,1.13-11.5; p = 0.034). Also, the EUS-TMD group had greater technical success (OR,16.96; 95%CI,4.69-81.62; p < 0.001) and overall success (OR, 3.09; 95%CI,1.18-8-16; p < 0.026) with a lower AEs rate (OR,0.30; 95%CI,0.11-0.78; p = 0.014) than EUS-RV in malignant disorders. Conclusions: EUS-RV is a demanding technique with better outcomes in benign than in malignant biliopancreatic diseases. Comparison of the EUS-TMD group on malignant disorders showed worse outcomes with EUS-RV. Given these findings, maybe EUS-RV is not the best option for malignant biliopancreatic disorders." /> <meta name="DCTERMS.extent" content="11 p." /> <meta name="DC.format" content="application/pdf" /> <meta name="DC.language" content="eng" scheme="DCTERMS.RFC1766" /> <meta name="DC.publisher" content="Finnish Medical Society Duodecim" /> <meta name="DCTERMS.isFormatOf" content="Reproducci贸 del document publicat a: https://doi.org/10.1080/07853890.2024.2416607" /> <meta name="DCTERMS.isPartOf" content="Annals of Medicine, 2024, vol. 56, num.1" /> <meta name="DC.relation" content="https://doi.org/10.1080/07853890.2024.2416607" scheme="DCTERMS.URI" /> <meta name="DC.rights" content="cc by (c) Gornals Soler, Joan B. et al., 2024" /> <meta name="DC.rights" content="https://creativecommons.org/licenses/by-nc/4.0/" scheme="DCTERMS.URI" /> <meta name="DC.source" content="Articles publicats en revistes (Ci猫ncies Cl铆niques)" /> <meta name="DC.subject" content="Malalties del tracte biliar" /> <meta name="DC.subject" content="Cateterisme" /> <meta name="DC.subject" content="Colangiopancreaticografia retr貌grada endosc貌pica" /> <meta name="DC.subject" content="Drenatge" /> <meta name="DC.subject" content="Bilious diseases and biliousness" /> <meta name="DC.subject" content="Catheterization" /> <meta name="DC.subject" content="Endoscopic retrograde cholangiopancreatograph" /> <meta name="DC.subject" content="Drainage" /> <meta name="DC.title" content="Endoscopic ultrasound-guided biliary rendezvous after failed cannulation, and comparison between benign vs malignant biliopancreatic disorders: outcomes at a single tertiary-care centre" /> <meta name="DC.type" content="info:eu-repo/semantics/article" /> <meta name="DC.type" content="info:eu-repo/semantics/publishedVersion" /> <meta name="DC.identifier" content="751768" /> <meta name="DC.date" content="2024-11-14T16:54:43Z" scheme="DCTERMS.W3CDTF" /> <meta name="DC.rights" content="info:eu-repo/semantics/openAccess" /> <meta name="DC.identifier" content="39428568" /> <meta name="citation_keywords" content="info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion" /> <meta name="citation_title" content="Endoscopic ultrasound-guided biliary rendezvous after failed cannulation, and comparison between benign vs malignant biliopancreatic disorders: outcomes at a single tertiary-care centre" /> <meta name="citation_issn" content="0785-3890" /> <meta name="citation_publisher" content="Finnish Medical Society Duodecim" /> <meta name="citation_language" content="eng" /> <meta name="citation_author" content="Gornals Soler, Joan B." /> <meta name="citation_author" content="Sumalla-Garcia, Albert" /> <meta name="citation_author" content="Quintana, Sergi" /> <meta name="citation_author" content="Luna-Rodriguez, Daniel" /> <meta name="citation_author" content="Velasquez Rodriguez, Julio G." /> <meta name="citation_author" content="Puigcerver-Mas, Maria" /> <meta name="citation_author" content="Escuer-Turu, Julia" /> <meta name="citation_author" content="Maisterra, Sandra" /> <meta name="citation_author" content="Marin, Mar" /> <meta name="citation_author" content="Munoa, Virginia" /> <meta name="citation_author" content="Laquente, Berta" /> <meta name="citation_author" content="Busquets Barenys, Juli" /> <meta name="citation_pdf_url" content="https://diposit.ub.edu/dspace/bitstream/2445/216492/1/870382.pdf" /> <meta name="citation_date" content="2024-12-01" /> <meta name="citation_abstract_html_url" content="https://diposit.ub.edu/dspace/handle/2445/216492" /> <script type='text/javascript' src="/dspace/static/js/jquery/jquery-1.10.2.min.js"></script> <script type='text/javascript' src='/dspace/static/js/jquery/jquery-ui-1.10.3.custom.min.js'></script> <script type='text/javascript' src='/dspace/static/js/bootstrap/bootstrap.min.js'></script> <script type='text/javascript' src='/dspace/static/js/holder.js'></script> <script type="text/javascript" src="/dspace/utils.js"></script> <script type="text/javascript" src="/dspace/static/js/choice-support.js"> </script> <!-- /* <script type="text/javascript"> var _gaq = _gaq || []; _gaq.push(['_setAccount', 'UA-9816681-2']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 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href="/dspace/handle/2445/7982">Ci猫ncies Cl铆niques</a></li> <li><a href="/dspace/handle/2445/7983">Articles publicats en revistes (Ci猫ncies Cl铆niques)</a></li> </ol> </div> <div class="container"> <!-- Go to www.addthis.com/dashboard to customize your tools --> <script type="text/javascript" src="//s7.addthis.com/js/300/addthis_widget.js#pubid=ra-5579653e05792ba5" async="async"></script> <div class="addthis_sharing_toolbox"></div> <div class="well">Please use this identifier to cite or link to this item: <code>https://hdl.handle.net/2445/216492</code></div> <table class="table itemDisplayTable"> <tr><td class="metadataFieldLabel">Title: </td><td class="metadataFieldValue">Endoscopic ultrasound-guided biliary rendezvous after failed cannulation, and comparison between benign vs malignant biliopancreatic disorders: outcomes at a single tertiary-care centre</td></tr> <tr><td class="metadataFieldLabel">Author: </td><td class="metadataFieldValue"><a class="author"href="/dspace/browse?type=author&value=Gornals+Soler%2C+Joan+B.">Gornals Soler, Joan B.</a><br /><a class="author"href="/dspace/browse?type=author&value=Sumalla-Garcia%2C+Albert">Sumalla-Garcia, Albert</a><br /><a class="author"href="/dspace/browse?type=author&value=Quintana%2C+Sergi">Quintana, Sergi</a><br /><a class="author"href="/dspace/browse?type=author&value=Luna-Rodriguez%2C+Daniel">Luna-Rodriguez, Daniel</a><br /><a class="author"href="/dspace/browse?type=author&value=Velasquez+Rodriguez%2C+Julio+G.">Velasquez Rodriguez, Julio G.</a><br /><a class="author"href="/dspace/browse?type=author&value=Puigcerver-Mas%2C+Maria">Puigcerver-Mas, Maria</a><br /><a class="author"href="/dspace/browse?type=author&value=Escuer-Turu%2C+Julia">Escuer-Turu, Julia</a><br /><a class="author"href="/dspace/browse?type=author&value=Maisterra%2C+Sandra">Maisterra, Sandra</a><br /><a class="author"href="/dspace/browse?type=author&value=Marin%2C+Mar">Marin, Mar</a><br /><a class="author"href="/dspace/browse?type=author&value=Munoa%2C+Virginia">Munoa, Virginia</a><br /><a class="author"href="/dspace/browse?type=author&value=Laquente%2C+Berta">Laquente, Berta</a><br /><a class="author"href="/dspace/browse?type=author&value=Busquets+Barenys%2C+Juli">Busquets Barenys, Juli</a></td></tr> <tr><td class="metadataFieldLabel">Keywords: </td><td class="metadataFieldValue">Malalties del tracte biliar<br />Cateterisme<br />Colangiopancreaticografia retr貌grada endosc貌pica<br />Drenatge<br />Bilious diseases and biliousness<br />Catheterization<br />Endoscopic retrograde cholangiopancreatograph<br />Drainage</td></tr> <tr><td class="metadataFieldLabel">Issue Date: </td><td class="metadataFieldValue">1-Dec-2024</td></tr> <tr><td class="metadataFieldLabel">Publisher: </td><td class="metadataFieldValue">Finnish Medical Society Duodecim</td></tr> <tr><td class="metadataFieldLabel">Abstract: </td><td class="metadataFieldValue">Background: Endoscopic ultrasound (EUS)-guided biliary rendezvous (RV) is an EUS-assisted technique described as a rescue method in cases of failed biliary cannulation via endoscopic retrograde cholangiography (ERC). Current literature remains unclear regarding its current role. The study aim was to evaluate the effectiveness for biliary EUS-RV, and comparison between benign vs malignant biliopancreatic disorders. Methods: Retrospective observational study with prospective consecutive inclusion in a specific database from a tertiary-center. All patients with biliopancreatic diseases that underwent a EUS-assisted ERC between October-2010 and November-2022 for failed ERC were included. Main outcomes were technical/overall success. Secondary outcomes were safety, potential factors related to failure/success or safety; and a comparative analysis between EUS-RV and EUS-guided transmural drainage (TMD) in malignant cases. Results: A total of 69 patients who underwent EUS-RV procedures, with benign and malignant pathologies (n = 40 vs n = 29), were included. Technical / overall success and related-adverse events (AEs) were 79.7% (95%CI, 68.3-88.4) / 74% (95%CI, 61-83.7) and 24% (95%CI, 15.1-36.5), respectively. Failed cases were mainly related with guidewire manipulation. Seven failed RV were successfully rescued by EUS-TMD. On multivariable analysis, EUS-RV and malignant pathology was associated with a greater failure rate (technical success: OR,0.21; 95%CI,0.05-0.72; p = 0.017), and higher AEs rate (OR,3.46; 95%CI,1.13-11.5; p = 0.034). Also, the EUS-TMD group had greater technical success (OR,16.96; 95%CI,4.69-81.62; p < 0.001) and overall success (OR, 3.09; 95%CI,1.18-8-16; p < 0.026) with a lower AEs rate (OR,0.30; 95%CI,0.11-0.78; p = 0.014) than EUS-RV in malignant disorders. Conclusions: EUS-RV is a demanding technique with better outcomes in benign than in malignant biliopancreatic diseases. Comparison of the EUS-TMD group on malignant disorders showed worse outcomes with EUS-RV. Given these findings, maybe EUS-RV is not the best option for malignant biliopancreatic disorders.</td></tr> <tr><td class="metadataFieldLabel">Note: </td><td class="metadataFieldValue">Reproducci贸 del document publicat a: https://doi.org/10.1080/07853890.2024.2416607</td></tr> <tr><td class="metadataFieldLabel">It is part of: </td><td class="metadataFieldValue">Annals of Medicine, 2024, vol. 56, num.1</td></tr> <tr><td class="metadataFieldLabel">URI: </td><td class="metadataFieldValue"><a href="https://hdl.handle.net/2445/216492">https://hdl.handle.net/2445/216492</a></td></tr> <tr><td class="metadataFieldLabel">Related resource: </td><td class="metadataFieldValue"><a href="https://doi.org/10.1080/07853890.2024.2416607">https://doi.org/10.1080/07853890.2024.2416607</a></td></tr> <tr><td class="metadataFieldLabel">ISSN: </td><td class="metadataFieldValue">0785-3890</td></tr> <tr><td class="metadataFieldLabel">Appears in Collections:</td><td class="metadataFieldValue"><a href="/dspace/handle/2445/7983">Articles publicats en revistes (Ci猫ncies Cl铆niques)</a><br/><a href="/dspace/handle/2445/67491">Articles publicats en revistes (Institut d'lnvestigaci贸 Biom猫dica de Bellvitge (IDIBELL))</a><br/></td></tr> </table><br/> <div class="panel panel-info"><div class="panel-heading">Files in This Item:</div> <table class="table panel-body"><tr><th id="t1" class="standard">File</th> <th id="t2" class="standard">Description</th> <th id="t3" class="standard">Size</th><th id="t4" class="standard">Format</th><th> </th></tr> <tr><td headers="t1" class="standard"><a target="_blank" href="/dspace/bitstream/2445/216492/1/870382.pdf">870382.pdf</a></td><td headers="t2" class="standard"></td><td headers="t3" class="standard">848.96 kB</td><td headers="t4" class="standard">Adobe PDF</td><td class="standard" align="center"><a class="btn btn-primary" target="_blank" href="/dspace/bitstream/2445/216492/1/870382.pdf">View/Open</a></td></tr></table> </div> <div class="container row"> <a class="btn btn-default" href="/dspace/handle/2445/216492?mode=full"> Show full item record </a> </div> <br/> <br/> <p class="submitFormHelp alert alert-info"> This item is licensed under a <a rel="license" href="https://creativecommons.org/licenses/by-nc/4.0/">Creative Commons License</a> <a rel="license" href="https://creativecommons.org/licenses/by-nc/4.0/"><img src="/dspace/image/by-nc.png" width=100 border="0" alt="Creative Commons" /></a> <!-- a href="https://creativecommons.org/licenses/by-nc/4.0/"><img src="/dspace/image/cc-somerights.gif" border="0" alt="Creative Commons" style="margin-top: -5px;" class="pull-right"/></a --> <!-- %= cc_rdf % --> </p> <div class="addthis_sharing_toolbox"></div> </div> </main> <footer class="navbar navbar-inverse navbar-bottom" style='background:-webkit-linear-gradient(#6685a9,#406086);background:-o-linear-gradient(#6685a9,#406086);background:-moz-linear-gradient(#6685a9,#406086);background:linear-gradient(#6685a9,#406086);border-radius:0;border:0;width:100%'> <div id="designedby" class="container text-muted"> <!-- fmt:message key="jsp.layout.footer-default.theme-by"/> <a href="http://www.cineca.it"><img src="/dspace/image/logo-cineca-small.png" alt="Logo CINECA" /></a --> <div id="footer_feedback" class="pull-left"> <p class="text-muted"> <span style='color:white'>Coordination: </span> <a style='color:#000' onMouseOver="this.style.color='#fff'" onMouseOut="this.style.color='#000'" target='_blank' href='http://crai.ub.edu/en'> CRAI Universitat de Barcelona</a> <a style='color:#000' onMouseOver="this.style.color='#fff'" onMouseOut="this.style.color='#000'" target="_blank" href='http://www.ub.edu/web/ub/en/menu_peu/avislegal/avis_legal.html'>Legal notice</a> </p> </div> <div id="footer_feedback" class="pull-right"> <p class="text-muted"> <span style='color:white'>Metadata subject to: </span> <a target='_blank' href='http://creativecommons.org/publicdomain/zero/1.0/'> <img src="/dspace/image/logoCC.png" alt="Logo CC" /> </a> <span style='color:white'>Powered by: </span> <a style='color:#000' onMouseOver="this.style.color='#fff'" onMouseOut="this.style.color='#000'" target="_blank" href="http://dspace.org/">DSpace</a> <a style='color:#000' onMouseOver="this.style.color='#fff'" onMouseOut="this.style.color='#000'" target="_blank" href="/dspace/feedback">Contact us</a> </p> </div> <!-- div id="footer_feedback" class="pull-right"> <p class="text-muted"><a target="_blank" href="http://www.dspace.org/">DSpace Software</a> Copyright © 2002-2013 <a target="_blank" href="http://www.duraspace.org/">Duraspace</a> - <a target="_blank" href="/dspace/feedback">Contact us</a> <a href="/dspace/htmlmap"></a></p> </div --> </div> </footer> </body> </html>