Protective Effects of Vitamin C and Vitamin E on Experimentally Induced Testicular Torsion and Detorsion in Rat Model

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and Vitamin E on Experimentally Induced Testicular Torsion and Detorsion in Rat Model</title> <meta name="description" content="Protective Effects of Vitamin C and Vitamin E on Experimentally Induced Testicular Torsion and Detorsion in Rat Model"> <meta name="keywords" content="vitamin C, vitamin E, standard tubular diameter, standard epithelial height, testicular torsion"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a 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87410</div> </div> </div> </div> <div class="card publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Protective Effects of Vitamin C and Vitamin E on Experimentally Induced Testicular Torsion and Detorsion in Rat Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anu%20Vinod%20Ranade">Anu Vinod Ranade</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aim: To evaluate and compare the effects of Vitamin C and Vitamin E on experimentally induced testicular torsion and detorsion in rats. Methods: Forty Male Wistar Albino rats were divided into five groups. Animals in the Group I underwent Sham operation, Group II consisted of animals that were subjected to torsion for three hours followed by detorsion for 24 hours without any treatment. While Group III, IV and V were orally pretreated with Vitamin C (40mg/kg.bw), vitamin E (100mg/kg.bw) and a combination of Vitamin C and vitamin E respectively for a period of 30 days. The testes of the experimental groups were manually rotated to 720掳 clockwise for three hours and counter rotated for 24 hours to induce ischemia and reperfusion. Sequential biopsies were performed and the testes were collected at the end of 24 hours of detrosion for morphological evaluation. Result: There was a significant decrease in the standard tubular diameter and the epithelial height of the seminiferous tubules in the untreated group when compared to Sham controls. The standard tubular diameter and seminiferous epithelial height showed near normal values when animals were pretreated with Vitamin C and Vitamin E individually or in combination. Conclusion: The results showed that pretreatment of with antioxidants vitamin E and vitamin C when administered prior to testicular torsion in rats significantly reduced the torsion and detorsion induced histopathlogical injury. <iframe src="https://publications.waset.org/abstracts/29446.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vitamin%20C" title="vitamin C">vitamin C</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20E" title=" vitamin E"> vitamin E</a>, <a href="https://publications.waset.org/abstracts/search?q=standard%20tubular%20diameter" title=" standard tubular diameter"> standard tubular diameter</a>, <a href="https://publications.waset.org/abstracts/search?q=standard%20epithelial%20height" title=" standard epithelial height"> standard epithelial height</a>, <a href="https://publications.waset.org/abstracts/search?q=testicular%20torsion" title=" testicular torsion"> testicular torsion</a> </p> <a href="https://publications.waset.org/abstracts/29446/protective-effects-of-vitamin-c-and-vitamin-e-on-experimentally-induced-testicular-torsion-and-detorsion-in-rat-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29446.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">316</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" 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Protective Effects of Vitamin C and Vitamin E on Experimentally Induced Testicular Torsion and Detorsion in Rat Model