chameleon - Product range

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a.hs-inline-web-interactive-168277755674:active:hover { } </style> <span class="hs-cta-wrapper hs-web-interactive-wrapper"><span class="hs-cta-node hs-web-interactive-node"> <a href="https://cta-service-cms2.hubspot.com/web-interactives/public/v1/track/click?encryptedPayload=AVxigLL%2BsCKf%2F4W8DcQbJWIMjrj3j8xE9riGhwmyaRyBdPitsEgOhZwSZcl1aAz66AZtilJlyTLVeD9xNM47dRCsSfHAjleDgKjW7y7eKrMKefHF%2Fbfbjk6mZ8Zr2ZC5yAo7ozIZDNPuIVK2bCOJCrscOiVeL5BbkSiSREGNEwsQdroo14DwZ2jjYSKQs7xihQ%3D%3D&portalId=6586853" class="hs-inline-web-interactive-168277755674 btn pink-btn " data-hubspot-cta-id="168277755674"> Book a demo </a> </span></span> </div></span> </div> </div> </div> </div> </div></div> </div> </div> </div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-3 main_area-row-1-padding main_area-row-1-max-width-section-centering dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-cell dnd-column" style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-4 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_widget_1699894161451" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"> <section class="o-section one-columns-text u-bg-white o-section--med" style=" "> <div class="container"> <div class="row"> <div class="col-lg-12 col-md-12"> <h3><b>A more efficient pathway to quality frozen grids for cryo-EM</b></h3> <p><span>Cryo-EM has developed into a powerful tool for studying the fine detail of biological structure required in areas such as drug discovery. Despite this, producing quality frozen grids with vitreous ice of an appropriate thickness and evenly distributed particles remains a key bottleneck in the structure determination workflow. </span></p> <p><span>We drew on decades of experience in structural biology process automation to create chameleon and provide optimizable vitrification for each unique sample behavior, reducing the time and costs associated with traditional trial-and-error methods.</span></p> </div> </div> </div> </section></div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-5 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_widget_1699894285601" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"> <section class="o-section full_width_image u-bg-white o-section--small" style="padding-top: 0; padding-bottom: 0; background-image: url('https://www.sptlabtech.com/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/chameleon-product-category---testimonials-1.jpg');"> <div class="container"> <div class="row"> <div class="col-md-12"> </div> </div> </div> </section></div> </div> </div> </div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-6 dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-cell dnd-column" style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-7 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_widget_1699894405219" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"><div class="o-section o-section--testimonial"> <div class="container"> <div class="row"> <div class="col-md-12"> <div class="c-testimonial"> <h2>chameleon in the lab</h2> <div id="c-mosquitoSlider"> <div class="c-testimonial__inner"> <div class="c-testimonial__image"> <img src="https://www.sptlabtech.com/hubfs/arvn-logo-rgb.png" alt="arvn-logo-rgb" loading="lazy" style="max-width: 100%; height: auto;"> </div> <div class="c-testimonial__text"> <div class="c-testimonial__quote"><p><span>"The chameleon has enabled an efficient cryoEM workflow for Arvinas by allowing us to freeze our samples promptly upon elution from the column, thus allowing rapid capture of complexes on grids ready for cryoEM data collection. By improving sample quality and reducing screening loads on microscopes, chameleon has allowed us to leverage both academic and industry partners for data collection."</span></p></div> <p class="c-testimonial__author">— Katie Digianantonio, PhD, Research Investigator, Arvinas</p> </div> </div> </div> </div> </div> </div> </div> </div></div> </div> </div> </div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-8 dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-cell dnd-column" style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-9 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_widget_1699895610022" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"><style> .beneifit-inner-title::after { content: none !important; } </style>  <div class="beneifit-module-block" id="beneifit-module-block"> <div class="container bullet-list-points"> <div class="beneifit-inner"> <div class="top-tabs-container desktop"> <label for="main-tab-1" class="active">chameleon</label> </div> <input class="tab-radio" id="main-tab-1" name="main-group" type="radio" checked> <div class="tabber-content"> <div class="beneifit-spec-tab"> <div class="tab_main_description"><h2>Optimize cryo-EM sample preparation workflows</h2> <p>chameleon streamlines cryo-EM sample preparation workflows with high speed blot-free vitrification, automated grid handling, and the ability to screen grids based on likely ice thickness. Guided workflows simplify set up, use, and cleaning of the instrument while the minimization of manual handling eliminates sample loss and damage.</p></div> <ul class="nav nav-tabs"> <li><a class="active" data-tab="tabCnt1" data-toggle="tab" href="#tabCnt1">chameleon<sup>®</sup></a></li> <li><a data-tab="tabCnt2" data-toggle="tab" href="#tabCnt2">Quantifoil<sup>®</sup> Active</a></li> </ul> <div class="tab-content"> <div id="tabCnt1" class="tab-pane in active tabCnt1"> <img src="https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/01%20-%20chameleon/chameleon_center_banner.png?width=225&height=300&name=chameleon_center_banner.png" width="225" height="300" loading="lazy" alt="chameleon_center_banner" style="height: auto; max-width: 100%; width: 225px; margin: 0px 40px 200px 20px; float: left;" srcset="https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/01%20-%20chameleon/chameleon_center_banner.png?width=113&height=150&name=chameleon_center_banner.png 113w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/01%20-%20chameleon/chameleon_center_banner.png?width=225&height=300&name=chameleon_center_banner.png 225w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/01%20-%20chameleon/chameleon_center_banner.png?width=338&height=450&name=chameleon_center_banner.png 338w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/01%20-%20chameleon/chameleon_center_banner.png?width=450&height=600&name=chameleon_center_banner.png 450w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/01%20-%20chameleon/chameleon_center_banner.png?width=563&height=750&name=chameleon_center_banner.png 563w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/01%20-%20chameleon/chameleon_center_banner.png?width=675&height=900&name=chameleon_center_banner.png 675w" sizes="(max-width: 225px) 100vw, 225px"><br> <h5>chameleon</h5> <h6>Next generation sample preparation for cryo-EM</h6> <p>chameleon delivers optimized grid vitrification for cryo-EM by combining next-generation automation, blotless grid technology, and high speed plunging. Thinking beyond existing sample preparation workflows enables routine high resolution structural studies.</p> <p style="text-align: center;"><span><a style="width: fit-content;" class="btn blue-btn" href="/products/chameleon/chameleon" rel="noopener">Explore chameleon</a></span></p> </div> <div id="tabCnt2" class="tab-pane in tabCnt2"> <img src="https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/Re-uploads/selfwicking-grids.jpg?width=225&height=188&name=selfwicking-grids.jpg" width="225" height="188" loading="lazy" alt="selfwicking-grids" style="height: auto; max-width: 100%; width: 225px; margin: 0px 40px 200px 20px; float: left;" srcset="https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/Re-uploads/selfwicking-grids.jpg?width=113&height=94&name=selfwicking-grids.jpg 113w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/Re-uploads/selfwicking-grids.jpg?width=225&height=188&name=selfwicking-grids.jpg 225w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/Re-uploads/selfwicking-grids.jpg?width=338&height=282&name=selfwicking-grids.jpg 338w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/Re-uploads/selfwicking-grids.jpg?width=450&height=376&name=selfwicking-grids.jpg 450w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/Re-uploads/selfwicking-grids.jpg?width=563&height=470&name=selfwicking-grids.jpg 563w, https://www.sptlabtech.com/hs-fs/hubfs/SPT%20Labtech%20Website/06%20-%20Products/05%20-%20chameleon/Re-uploads/selfwicking-grids.jpg?width=675&height=564&name=selfwicking-grids.jpg 675w" sizes="(max-width: 225px) 100vw, 225px"><br> <h5>Quantifoil Active</h5> <h6>Self-wicking grids for use exclusively with chameleon</h6> <p>QUANTIFOIL Active grids are unique in being the first commercially produced grids with copper nano-wire covered bars to promote thin film formation through a process of “self-wicking”. This novel grid technology removes the variability of applying an externally applied filter paper to remove excess sample during blotting.</p> <p style="text-align: center;"><span><a style="width: fit-content;" class="btn blue-btn" href="https://www.quantifoil.com/products/quantifoil-active" rel="noopener" target="_blank">Explore Quantifoil Active</a></span></p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-10 main_area-row-4-max-width-section-centering dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-cell cell_1647595913700-padding cell_1647595913700-background-color cell_1647595913700-background-layers cell_1647595913700-margin dnd-column" style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-11 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget 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widget-type-cell dnd-column" style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-14 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_widget_1699896430973" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"><div class="o-section c-slider c-mosquito--insights__slider"> <div class="container"> <div class="row"> <div class="col-md-4 c-slider__left"> <h2>Our insights explore the latest cryo-em trends.</h2> </div> <div class="col-md-8 c-slider__right"> <div id="blogSlider"> <div class="c-slider__block"> <a href="https://www.sptlabtech.com/hubfs/6586853/SPT%20Labtech%20Website/09%20-%20Resources/2023_MM_poster_OP.pdf"> </a><div class="c-slider__block-inner" style="background-image: url('https://www.sptlabtech.com/hubfs/Website/06%20-%20Products/04%20-%20firefly/video/Features-img-peer-to-peer%20%281%29.jpg');"><a href="https://www.sptlabtech.com/hubfs/6586853/SPT%20Labtech%20Website/09%20-%20Resources/2023_MM_poster_OP.pdf"> <div class="c-slider__block-bg"></div> <h3>Chamelogator: A software tool for Chameleon data analysis</h3> <p></p><p>Here, we report best-practices from early adopters of the chameleon technology, including experiences and lessons learned through recent case studies.</p> </a><a href="https://www.sptlabtech.com/hubfs/6586853/SPT%20Labtech%20Website/09%20-%20Resources/2023_MM_poster_OP.pdf" target="_blank" rel="noopener noreferrer"></a><p></p> <div class="c-slider__btn">Download the poster</div> </div> </div> <div class="c-slider__block"> <a href="https://www.sptlabtech.com/resources/novel-sample-preparation-techniques-cryo-em-register"> <div class="c-slider__block-inner" style="background-image: url('https://www.sptlabtech.com/hubfs/Website/06%20-%20Products/04%20-%20firefly/video/Features-img-peer-to-peer%20%281%29.jpg');"> <div class="c-slider__block-bg"></div> <h3>Utilising novel sample preparation techniques to enhance Cryo-EM structural analysis</h3> <p><span>Cryo-EM has been adopted into drug discovery workflows by the pharmaceutical and biotechnology industries having proved itself capable of delivering atomic resolution structures for key targets, including integral membrane proteins such as GPCRs and ion channels.</span></p> <div class="c-slider__btn">Watch the webinar</div> </div> </a> </div> <div class="c-slider__block"> <a href="https://www.sptlabtech.com/resources/strategies-for-resolving-sample-preparation-issues-in-cryo-em-register"> <div class="c-slider__block-inner" style="background-image: url('https://www.sptlabtech.com/hubfs/Website/06%20-%20Products/04%20-%20firefly/video/Features-img-peer-to-peer%20%281%29.jpg');"> <div class="c-slider__block-bg"></div> <h3>Strategies for resolving sample preparation issues in cryo-EM</h3> <p><span>The NIS and SPT Labtech expert discussion will be recorded at the Microscopy & Microanalysis Meeting 2022 in Portland and aims to cover key questions around best practice for dealing with sample preparation issues.</span></p> <div class="c-slider__btn">Watch the interview</div> </div> </a> </div> <div class="c-slider__block"> <a href="https://www.sptlabtech.com/resources/cryo-em-sample-preparation-with-chameleon"> <div class="c-slider__block-inner" style="background-image: url('https://www.sptlabtech.com/hubfs/Website/06%20-%20Products/04%20-%20firefly/video/Features-img-peer-to-peer%20%281%29.jpg');"> <div class="c-slider__block-bg"></div> <h3>Enabling a paradigm shift in cryo-EM sample preparation with chameleon</h3> <p><span>In this presentation with MIT.nano, SPT Labtech's cryo-EM development Scientist Michele Darrow discusses using new automation to overcome commonly experienced sample preparation bottlenecks ahead of the microscope.</span></p> <div class="c-slider__btn">Watch the webinar</div> </div> </a> </div> </div> </div> </div> </div> </div></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div data-global-resource-path="SPT-Labtech-2021/SPT-Labtech-Theme-2021/templates/partials/footer.html"><footer class="footer"> <div class="container"> <div class="container-fluid footer-inr"> <div class="row-fluid-wrapper"> <div class="row-fluid"> <div class="span12 widget-span widget-type-cell " style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-1 dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-cell dnd-column" style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-2 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" 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