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Structural Biology | SPT Labtech

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data-hs-cos-type="module"> <div class="application-banner image" style="background-image: url('https://www.sptlabtech.com/hubfs/Website/04%20-%20Structural%20Biology/Structural-Biology---hero.jpg')"> <div class="overlay"> <div class="grey-overlay"> <div class="container"> <div class="breadcrumb-container"> <ol class="breadcrumb custom-breadcrumb"> <li class="breadcrumb-item" data="1"><a href="/">Home</a></li> <li class="breadcrumb-item"> Structural Biology </li> </ol> </div> </div> <div class="container"> <div class="flex"> <div class="application-bnr-text medium"> <div class="text-block"> <h1 class="title-symbol">Structural <br>Biology</h1> <div id="hs_cos_wrapper_widget_1629795891799_" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_inline_rich_text" style="" data-hs-cos-general-type="widget" data-hs-cos-type="inline_rich_text" data-hs-cos-field="banner_content.description"><p><span>The dynamic field of structural biology investigates the molecular structure of biological macromolecules to understand fundamental life processes and tackle disease.</span></p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div></div> </div><!--end widget-span --> </div><!--end row--> </div><!--end row-wrapper --> </div><!--end widget-span --> </div><!--end row--> </div><!--end row-wrapper --> <div class="row-fluid-wrapper row-depth-1 row-number-3 main_area-row-1-padding main_area-row-1-max-width-section-centering dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-cell dnd-column" style="" data-widget-type="cell" data-x="0" data-w="12"> <div class="row-fluid-wrapper row-depth-1 row-number-4 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_widget_1631270309708" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module widget-type-rich_text" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"><span id="hs_cos_wrapper_widget_1631270309708_" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_rich_text" style="" data-hs-cos-general-type="widget" data-hs-cos-type="rich_text"><h2>New techniques are revolutionizing structural biology</h2> <p>New technological advances and techniques in Cryo-EM and protein crystallography have inspired a structural biology revolution, enabling researchers to tackle even more complex biological problems to benefit scientific research. ‘Integrative’ structural biology brings together multiple approaches to build a more comprehensive picture of dynamic processes at both a cellular and molecular level.</p></span></div> </div><!--end widget-span --> </div><!--end row--> </div><!--end row-wrapper --> </div><!--end widget-span --> </div><!--end row--> </div><!--end row-wrapper --> <div class="row-fluid-wrapper row-depth-1 row-number-5 dnd-section"> <div class="row-fluid "> <div 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text-right"> <div class="anchor-point" id="electron-microscopy"> <i> <img src="https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=98&amp;height=98&amp;name=microscope-icon.png" alt="microscope-icon" loading="loading=" "" width="98" height="98" srcset="https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=49&amp;height=49&amp;name=microscope-icon.png 49w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=98&amp;height=98&amp;name=microscope-icon.png 98w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=147&amp;height=147&amp;name=microscope-icon.png 147w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=196&amp;height=196&amp;name=microscope-icon.png 196w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=245&amp;height=245&amp;name=microscope-icon.png 245w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=294&amp;height=294&amp;name=microscope-icon.png 294w" sizes="(max-width: 98px) 100vw, 98px"> </i> <h3>Transmission electron <br>microscopy</h3> <p>Transmission electron microscopy is a promising and adaptable technique providing researchers with valuable insights on intricate biological structures ranging from individual biomolecules to whole cells.</p> <a href="/products?application-area=Structural+biology" class="btn"> Explore related products </a> </div> </div> </div> </div> </div> </div> </div> </div></div> </div><!--end widget-span --> </div><!--end row--> </div><!--end row-wrapper --> <div class="row-fluid-wrapper row-depth-1 row-number-6 dnd-section"> <div class="row-fluid "> <div class="span12 widget-span 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https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=98&amp;height=98&amp;name=microscope-icon.png 98w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=147&amp;height=147&amp;name=microscope-icon.png 147w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=196&amp;height=196&amp;name=microscope-icon.png 196w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=245&amp;height=245&amp;name=microscope-icon.png 245w, https://www.sptlabtech.com/hs-fs/hubfs/Website/00%20-%20Reusable%20Assets/icons/microscope-icon.png?width=294&amp;height=294&amp;name=microscope-icon.png 294w" sizes="(max-width: 98px) 100vw, 98px"> </i> <h3><strong>Cryo-Electron </strong><br>Microscopy (Cryo-EM)</h3> <p>Cryo-EM has ushered in a new era of scientific discovery with the production of increasingly higher-resolution structural information.&nbsp; Advances in hardware and software have now opened up the technique to more widespread adoption in basic research and drug discovery.</p> <a href="https://www.sptlabtech.com/applications/structural-biology/cryo-em" class="btn"> Learn more </a> </div> </div> <div class="col-md-6"> <div class="sub-module2-content text-center"> <i> <img src="https://www.sptlabtech.com/hubfs/Website/00%20-%20Reusable%20Assets/icons/protein-icon.png" alt="protein-icon" loading="lazy" style="max-width: 100%; height: auto;"> </i> <h3><strong>Single Particle </strong><br>Analysis</h3> <p>Single particle analysis (SPA) is a well-established cryo-electron microscopy technique, allowing structural biologists to investigate the detailed structures of macromolecules at near-atomic resolution to uncover rich biological insights.</p> <a href="/products?sub-application=Single+Particle+Analysis" class="btn"> Explore related products </a> </div> </div> <div class="col-md-6"> <div class="sub-module2-content text-center"> <i> <img src="https://www.sptlabtech.com/hubfs/Website/00%20-%20Reusable%20Assets/icons/molecule-icon.png" alt="molecule-icon" loading="lazy" style="max-width: 100%; height: auto;"> </i> <h3><strong>Cryo-Tomography</strong></h3> <p>Cryo-electron tomography (cryo-ET) uses 3D molecular-level imaging to produce high-resolution structural and spatial information about individual proteins and the cellular environment where they operate.</p> <a href="https://www.sptlabtech.com/products/quantifoil" class="btn" target="_blank" rel="noopener"> Explore our range of quantifoil products </a> </div> </div> <div class="col-md-6"> <div class="sub-module2-content text-center"> <i> <img src="https://www.sptlabtech.com/hubfs/Website/00%20-%20Reusable%20Assets/icons/doc-with-magnify-icon.png" alt="doc-with-magnify-icon" loading="lazy" style="max-width: 100%; height: auto;"> </i> <h3><strong>Micro Electron Diffraction</strong></h3> <p>Micro electron diffraction (MicroED) is a developing technique for determining the structure of proteins from nanocrystals bringing together cryo-EM sample preparation approaches with electron and X-ray crystallography data analytics.</p> <a href="https://www.sptlabtech.com/products/quantifoil" class="btn"> Explore our range of quantifoil products </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <!--Sub Application Module 2--> </div><!--end widget-span --> </div><!--end row--> </div><!--end row-wrapper --> <div class="row-fluid-wrapper row-depth-1 row-number-7 dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_main_area-module-5" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"><div class="sub-application-module"> <div class="container 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Obtaining crystals of a high enough resolution for X-ray diffraction studies can be time and cost intensive, requiring an extensive number of screening and optimization experiments to determine ideal conditions for crystal growth.</p> <a href="https://www.sptlabtech.com/applications/structural-biology/protein-crystallography" class="btn"> Learn more </a> </div> </div> </div> </div> </div> </div> </div> </div></div> </div><!--end widget-span --> </div><!--end row--> </div><!--end row-wrapper --> <div class="row-fluid-wrapper row-depth-1 row-number-8 dnd-section"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <!--Sub Application Module 2--> <div class="sub-application-module"> <div class="container bullet-list-points"> <div class="sub-app-inr" style="background:rgba(255, 255, 255,1.0"> <div class="sub-app-module2"> <div class="anchor-point" id="sub-application-module"> <div class="sub-app-module2-inr"> <div class="row"> <div class="col-md-6"> <div class="sub-module2-content text-center"> <i> <img src="https://www.sptlabtech.com/hubfs/Website/00%20-%20Reusable%20Assets/icons/resources-icon-poster.png" alt="resources-icon-poster" loading="lazy" style="max-width: 100%; height: auto;"> </i> <h3><strong>Protein crystallography methods</strong></h3> <p>Protein crystallography encompasses a range of techniques such as vapor diffusion and batch crystallization methods to deliver protein structure data in dynamic research environments. 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