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/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2f5a7ff3728372e62cc123b00a74b2cbec344797-1200x724.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2f5a7ff3728372e62cc123b00a74b2cbec344797-1200x724.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2f5a7ff3728372e62cc123b00a74b2cbec344797-1200x724.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2f5a7ff3728372e62cc123b00a74b2cbec344797-1200x724.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2f5a7ff3728372e62cc123b00a74b2cbec344797-1200x724.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2f5a7ff3728372e62cc123b00a74b2cbec344797-1200x724.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2F2f5a7ff3728372e62cc123b00a74b2cbec344797-1200x724.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-contain" loading="lazy"/></noscript></span></a></div><div class="border-t-gray-100 border-t-2 flex-auto py-2 "><span class="text-sm text-gray-500 py-2">February 17th 2025</span><div class="py-3"><a class="lg:text-[20px] text-[19px] font-[500]" href="/view/2-immunotherapy-options-show-comparable-benefits-in-extensive-stage-small-cell-lung-cancer">2 Immunotherapies Show Comparable Benefits in Extensive-Stage Small Cell Lung Cancer</a></div><div class="pb-2"><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/hayden-e-klein"><i>Hayden E. Klein</i></a></span></div></div><a href="/view/2-immunotherapy-options-show-comparable-benefits-in-extensive-stage-small-cell-lung-cancer"><a href="/view/2-immunotherapy-options-show-comparable-benefits-in-extensive-stage-small-cell-lung-cancer"><p class="mt-1 text-gray-800 text-[13px] line-clamp-6 text-hidden">When added to chemotherapy, researchers found no significant difference in overall or progression-free survival between PD-1 and PD-L1 inhibitors.</p></a></a></div></div><div class="flex-wrap w-[60%] flex "><a class="flex w-[50%] flex-col sm:pl-[35px] pl-[20px] pb-[35px] " href="/view/study-finds-declining-sclc-incidence-but-stagnant-survival-rates"><div class="w-full lg:h-[134px] h-[100px] relative bg-default-logo-background "><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" class="lg:object-cover object-contain " style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fcfb706b50be1f17b68f7a1eef146583c4f2d7741-8192x4608.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="lg:object-cover object-contain " loading="lazy"/></noscript></span></div><div class="border-t-gray-100 border-t-2 pt-2 pb-2 flex-auto "><a href="/view/study-finds-declining-sclc-incidence-but-stagnant-survival-rates"><span class="text-sm text-gray-500">February 7th 2025</span></a><div><a class="text-[14px]" href="/view/study-finds-declining-sclc-incidence-but-stagnant-survival-rates"><p class="line-clamp-4 text-hidden font-[500]">Study Finds Declining SCLC Incidence, but Stagnant Survival Rates</p></a></div><div class="py-2"><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/hayden-e-klein"><i>Hayden E. 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Klein</i></a></span></div></div></div></div></a><a target="" style="scroll-snap-align:center;text-decoration:none" class="jsx-2915913710 sm:w-[280px] xs:w-[240px] w-[65%] h-auto flex flex-col space-y-3 flex-none select-none no-underline" href="/view/emerging-therapies-shine-hope-on-small-cell-lung-cancer-treatment"><div class="jsx-2915913710 w-full h-full flex flex-col overflow-hidden relative bg-white text-center"><div class="jsx-2915913710 relative w-full shadow-md shadow-grey-800 aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" class="object-cover" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fe6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-cover" loading="lazy"/></noscript></span></div><div class="jsx-2915913710 content-wrap"><span class="jsx-2915913710 py-3 text-sm text-gray-500 text-left"><i class="jsx-2915913710">January 28th 2025</i></span><div class="jsx-2915913710 w-full h-fit mb-4"><p class="jsx-2915913710 text-[18px] font-bold text-[#000000] text-left line-clamp-3 text-hidden">Emerging Therapies Shine Hope on Small Cell Lung Cancer Treatment</p></div><div class="jsx-2915913710 pb-2 text-left ]"><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/hayden-e-klein"><i>Hayden E. 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strategies for optimizing care.</p><div style="color:var(--primary)"><a class="font-bold font-rubik text-xs flex items-center gap-2 mt-2.5 xs:mt-4 lg:mt-2.5 xl:mt-3.5 py-2 px-3 cursor-pointer max-w-fit bg-white hover:bg-gray-300 rounded-md" href="https://bit.ly/4eXmhI9">Visit Now</a></div></div><div class="w-full max-h-[385px] lg:max-h-[243px] xl:max-h-[311px] overflow-hidden flex justify-center items-center rounded-br-none rounded-tr-md rounded-tl-md lg:rounded-r-md lg:rounded-tl-none pointer-events-none"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" 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class="w-[30%] text-right text-[#0AA2BE] text-[16px] underline"><span>View All</span></a></div><div style="scroll-snap-type:none" class="jsx-19ede9f0a5a45918 flex items-start overflow-x-auto space-x-4 py-4 relative mx-auto w-[calc(100%-64px)]"><a target="" style="scroll-snap-align:center;text-decoration:none" class="jsx-1215160397 sm:w-[280px] xs:w-[240px] w-[65%] h-auto flex flex-col space-y-3 flex-none select-none no-underline" href="/view/dr-mark-socinski-on-the-impact-of-targeted-therapies-for-patients-with-lung-cancer"><div class="jsx-1215160397 w-full h-full flex flex-col overflow-hidden relative bg-white text-center"><div class="jsx-1215160397 relative w-full shadow-md shadow-grey-800 aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" 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loading="lazy"/></noscript></span></div><div class="jsx-1215160397 content-wrap"><span class="jsx-1215160397 py-3 text-sm text-gray-500 text-left"><i class="jsx-1215160397">December 21st 2023</i></span><div class="jsx-1215160397 w-full h-fit mb-4"><p class="jsx-1215160397 text-[18px] font-bold text-[#000000] text-left line-clamp-3 text-hidden">Dr Mark Socinski on How Targeted Therapies Have Impacted Lung Cancer Outcomes</p></div></div></div></a><a target="" style="scroll-snap-align:center;text-decoration:none" class="jsx-1637274924 sm:w-[280px] xs:w-[240px] w-[65%] h-auto flex flex-col space-y-3 flex-none select-none no-underline" href="/view/dr-mark-socinski-discusses-the-impacts-of-immunotherapy-on-lung-cancer-outcomes"><div class="jsx-1637274924 w-full h-full flex flex-col overflow-hidden relative bg-white text-center"><div class="jsx-1637274924 relative w-full shadow-md shadow-grey-800 aspect-video"><span 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style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-cover" loading="lazy"/></noscript></span></div><div class="jsx-1637274924 content-wrap"><span class="jsx-1637274924 py-3 text-sm text-gray-500 text-left"><i class="jsx-1637274924">November 22nd 2023</i></span><div class="jsx-1637274924 w-full h-fit mb-4"><p class="jsx-1637274924 text-[18px] font-bold text-[#000000] text-left line-clamp-3 text-hidden">Dr Mark Socinski Discusses the Impacts of Immunotherapy on Lung Cancer Outcomes</p></div></div></div></a><a target="" style="scroll-snap-align:center;text-decoration:none" class="jsx-286612495 sm:w-[280px] xs:w-[240px] w-[65%] h-auto flex flex-col space-y-3 flex-none select-none no-underline" href="/view/dr-mark-socinski-on-the-heterogeneity-of-lung-cancer-and-targeted-treatment"><div class="jsx-286612495 w-full h-full flex 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style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-cover" loading="lazy"/></noscript></span></div><div class="jsx-286612495 content-wrap"><span class="jsx-286612495 py-3 text-sm text-gray-500 text-left"><i class="jsx-286612495">November 10th 2023</i></span><div class="jsx-286612495 w-full h-fit mb-4"><p class="jsx-286612495 text-[18px] font-bold text-[#000000] text-left line-clamp-3 text-hidden">Dr Mark Socinski on the Heterogeneity of Lung Cancer and Targeted Treatment</p></div></div></div></a><a target="" style="scroll-snap-align:center;text-decoration:none" class="jsx-2915913710 sm:w-[280px] xs:w-[240px] w-[65%] h-auto flex flex-col space-y-3 flex-none select-none no-underline" href="/view/dr-robert-daly-on-benefits-of-at-home-lung-cancer-treatment"><div class="jsx-2915913710 w-full h-full flex flex-col 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style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="object-cover" loading="lazy"/></noscript></span></div><div class="jsx-1215160397 content-wrap"><span class="jsx-1215160397 py-3 text-sm text-gray-500 text-left"><i class="jsx-1215160397">September 24th 2023</i></span><div class="jsx-1215160397 w-full h-fit mb-4"><p class="jsx-1215160397 text-[18px] font-bold text-[#000000] text-left line-clamp-3 text-hidden">Insufficient Data, Disparities Plague Lung Cancer Risk Factor Documentation </p></div></div></div></a></div></div></div><div class="flex items-center space-x-4 border-0 border-b border-secondary select-none py-1"><h2 class="text-3xl text-primary">More News</h2></div><div class="flex flex-wrap w-full pb-4"><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-1"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/fda-proposal-aims-to-reduce-smoking-addiction-and-sclc-cases"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/52357f076f157d526c1536563d6da838936cab75-6240x4160.jpg?fit=crop&auto=format" alt="Hands holding pack of cigarettes | Image credit: Nopphon – stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">Published: January 16th 2025 | Updated: January 29th 2025</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/fda-proposal-aims-to-reduce-smoking-addiction-and-sclc-cases">FDA Proposal Aims to Reduce Smoking Addiction and SCLC Cases</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/hayden-e-klein">Hayden E. Klein</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/fda-proposal-aims-to-reduce-smoking-addiction-and-sclc-cases"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Small cell lung cancer (SCLC) is strongly linked to smoking, with about 80% of lung cancer deaths attributed to tobacco use.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/lung-cancer-screening-facilities-least-accessible-to-american-indian-alaska-native-patients-rural-communities"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a5d4a9244182058e2b8979906a48d466eb8850ad-5184x3456.jpg?fit=crop&auto=format" alt="Patient receiving lung cancer screening results | Image Credit: Nattakorn - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">January 13th 2025</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/lung-cancer-screening-facilities-least-accessible-to-american-indian-alaska-native-patients-rural-communities">Lung Cancer Screening Facilities Least Accessible to American Indian/Alaska Native Patients, Rural Communities</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/brooke-mccormick">Brooke McCormick</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/lung-cancer-screening-facilities-least-accessible-to-american-indian-alaska-native-patients-rural-communities"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Some populations face significant disparities in accessing lung cancer screening facilities, with American Indian/Alaska Native (AI/AN)-majority and rural census tracts facing the greatest travel distances.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/considerations-for-immunotherapy-duration-in-nsclc-dr-heather-wakelee"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/bd69a27ab273485d32244ba307bad35ccaee1a85-2880x1616.png?fit=crop&auto=format" alt="Heather Wakelee, MD" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 11th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/considerations-for-immunotherapy-duration-in-nsclc-dr-heather-wakelee">Considerations for Immunotherapy Duration in NSCLC: Dr Heather Wakelee</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/considerations-for-immunotherapy-duration-in-nsclc-dr-heather-wakelee"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Heather Wakelee, MD, Stanford University, discusses the pros and cons of different durations of immunotherapy in non-small cell lung cancer (NSCLC) and the future outlook for patient-specific care. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/different-options-for-different-people-dr-bellinda-king-kallimanis-explores-the-state-of-patient-education-in-lung-cancer"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/38975b6298f4f0a769e094984cec9357602e8bfd-8064x5376.jpg?fit=crop&auto=format" alt="Diverse representation in health care materials is one of multiple factors that could benefit patient education initiatives | image credit: Fitry - stock.adobe.come" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 10th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/different-options-for-different-people-dr-bellinda-king-kallimanis-explores-the-state-of-patient-education-in-lung-cancer">Different Options for Different People: Dr Bellinda King-Kallimanis Explores the State of Patient Education in Lung Cancer</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/different-options-for-different-people-dr-bellinda-king-kallimanis-explores-the-state-of-patient-education-in-lung-cancer"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Bellinda King-Kallimanis, PhD, LUNGevity Foundation, reflects on her experiences in patient-focused research to discuss the current state of patient education, the importance of patient advocates, and mediating barriers to health care access. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/dr-sandip-patel-previews-the-highly-anticipated-50th-anniversary-of-wclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/f92fc2fde7f057e5f31febb96056ccca1dc91888-2880x1616.png?fit=crop&auto=format" alt="Sandip Patel, MD" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 6th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/dr-sandip-patel-previews-the-highly-anticipated-50th-anniversary-of-wclc">Dr Sandip Patel Previews the Highly Anticipated 50th Anniversary of WCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kyle-munz">Kyle Munz</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/dr-sandip-patel-previews-the-highly-anticipated-50th-anniversary-of-wclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The 2024 World Conference on Lung Cancer (WCLC) marks the 50th anniversary of the International Association for the Study of Lung Cancer. Sandip Patel, MD, joined for an interview looking forward to the unique features of this year's meeting. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/late-stage-trial-discontinued-due-to-adverse-events"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/46ed1f28dea92f2cb13e14b5856c7258caea556e-5000x3750.jpg?fit=crop&auto=format" alt="Lung cancer | Image credit: Sebastian Kaulitzki - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">August 8th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/late-stage-trial-discontinued-due-to-adverse-events">Late-Stage Vibostolimab, Pembrolizumab Plus Chemotherapy Trial Discontinued Due to Adverse Events</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/julia-bonavitacola">Julia Bonavitacola</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/late-stage-trial-discontinued-due-to-adverse-events"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A high number of adverse events were reported in a late-stage trial conducted by Merck for treatment in lung cancer.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-7"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/shared-decision-making-for-lung-cancer-screening-more-straw-for-the-camel-s-back"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/5421358c8f117ee86126333e135f08cf1e61ded6-778x382.png?fit=crop&auto=format" alt="AJMC" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 31st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/shared-decision-making-for-lung-cancer-screening-more-straw-for-the-camel-s-back">Shared Decision-Making for Lung Cancer Screening: More Straw for the Camel’s Back</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/jonas-b-green-md-mph-mshs">Jonas B. Green, MD, MPH, MSHS</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/shared-decision-making-for-lung-cancer-screening-more-straw-for-the-camel-s-back"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">This editorial describes the need for a system that helps primary care physicians prioritize shared decision-making for preventive services.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/tarlatamab-receives-accelerated-approval-for-extensive-stage-sclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/db6c88afb196508d8ce41e2f72273ee54168e353-6000x4000.jpg?fit=crop&auto=format" alt="Doctor with health care icons and FDA | Image credit: wladimir1804 - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">May 17th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/tarlatamab-receives-accelerated-approval-for-extensive-stage-sclc">Tarlatamab Receives Accelerated Approval for Extensive-Stage SCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/laura-joszt">Laura Joszt, MA</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/tarlatamab-receives-accelerated-approval-for-extensive-stage-sclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The FDA has approved tarlatamab (Imdelltra; Amgen), a novel bispecific T-cell engager, to treat patients with extensive-stage small cell lung cancer (SCLC).</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/top-5-most-read-lung-cancer-articles-of-2023"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/796347f961045d4dadcbd28a768a698101c153bc-3187x1625.png?fit=crop&auto=format" alt="Top 5 Most-Read Lung Cancer Articles of 2023" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">December 25th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/top-5-most-read-lung-cancer-articles-of-2023">Top 5 Most-Read Lung Cancer Articles of 2023</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/julia-bonavitacola">Julia Bonavitacola</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/top-5-most-read-lung-cancer-articles-of-2023"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Our most-read content that featured lung cancer included articles on non–small cell lung cancer, how navigation programs can increase screening rates, and a potential link between antidepressants and lung cancer risk.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/tarlatamab-application-for-sclc-granted-priority-review-by-fda"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/e6fc92fc0236504a1b3f0c2a303f176b0b279d1c-4500x3000.jpg?fit=crop&auto=format" alt="Lung cancer | Image credit: Dr_Microbe - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">December 14th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/tarlatamab-application-for-sclc-granted-priority-review-by-fda">Tarlatamab Application for SCLC Granted Priority Review by FDA</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/julia-bonavitacola">Julia Bonavitacola</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/tarlatamab-application-for-sclc-granted-priority-review-by-fda"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The treatment developed by Amgen could be the first therapeutic option approved for third-line treatment of advanced small cell lung cancer (SCLC).</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/aerobic-exercise-tai-chi-improved-sleep-in-patients-with-lung-cancer"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/62d2a3b079833eb4f32e8ce1d93cdb76ccd8c9b5-4928x3264.jpg?fit=crop&auto=format" alt="Tai chi chuan | Image credit: Markgraf Ave - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">December 13th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/aerobic-exercise-tai-chi-improved-sleep-in-patients-with-lung-cancer">Aerobic Exercise, Tai Chi Improved Sleep in Patients With Lung Cancer</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/julia-bonavitacola">Julia Bonavitacola</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/aerobic-exercise-tai-chi-improved-sleep-in-patients-with-lung-cancer"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Improved psychological distress and physical function were among the benefits of doing aerobic exercise and tai chi as a patient with lung cancer.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/prediction-model-identified-risk-factors-for-ed-visits-in-patients-with-lung-cancer"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a502d33f191e80c9212d9abe8be1ccb8d782e058-5616x3744.jpg?fit=crop&auto=format" alt="Prediction Model Identified Risk Factors for ED Visits in Patients With Lung Cancer" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">December 7th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/prediction-model-identified-risk-factors-for-ed-visits-in-patients-with-lung-cancer">Prediction Model Identified Risk Factors for ED Visits in Patients With Lung Cancer</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/julia-bonavitacola">Julia Bonavitacola</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/prediction-model-identified-risk-factors-for-ed-visits-in-patients-with-lung-cancer"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">A risk prediction model that was based on machine learning could help to make resource utilization more efficient by correctly predicting emergency department (ED) visits in patients with lung cancer.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-13"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/early-ct-screening-significantly-improves-survival-in-lung-cancer"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/9f975ae9c2ee542c6552c8d164ca16788f849a8b-5000x3750.jpg?fit=crop&auto=format" alt="Lung cancer illustration | Image credit: SciePro - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 28th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/early-ct-screening-significantly-improves-survival-in-lung-cancer">Early CT Screening Significantly Improves Survival in Lung Cancer</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/rina-lokaj">Rina Lokaj</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/early-ct-screening-significantly-improves-survival-in-lung-cancer"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Early CT screening leads to a 20-year lung cancer survival rate of 81%. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/trilaciclib-may-reduce-hospitalization-and-improve-survival-in-es-sclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/66c1591b2bef5d67825d9c88b2fdb7bf9429f3d2-4577x2647.jpg?fit=crop&auto=format" alt="Hospital corridor | Image credit: VILevi - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 23rd 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/trilaciclib-may-reduce-hospitalization-and-improve-survival-in-es-sclc">Trilaciclib May Reduce Hospitalization and Improve Survival in ES-SCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/russ-conroy">Russ Conroy</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/trilaciclib-may-reduce-hospitalization-and-improve-survival-in-es-sclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Patients with extensive-stage small cell lung cancer (ES-SCLC) who receive trilaciclib appear to experience lower rates of hematologic adverse effects than those who are not treated with the agent.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-medicaid-coverage-errors-gender-disparities-in-health-research-improved-lung-cancer-survival-rates"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/703de894e882d8a6da8c19964dc1ca71b969d30c-2000x1046.png?fit=crop&auto=format" alt="What We’re Reading: Medicaid Coverage Errors; Gender Disparities in Health Research; Improved Lung Cancer Survival Rates" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 14th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-medicaid-coverage-errors-gender-disparities-in-health-research-improved-lung-cancer-survival-rates">What We’re Reading: Medicaid Coverage Errors; Gender Disparities in Health Research; Improved Lung Cancer Survival Rates</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/ajmc-staff">AJMC Staff</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-medicaid-coverage-errors-gender-disparities-in-health-research-improved-lung-cancer-survival-rates"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Up to 30 million individuals could lose Medicaid coverage; a new initiative demands increased focus on women's health issues; survey reports increased 5-year lung cancer survival rates from 2015 to 2019.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-expanded-lung-cancer-screening-guidelines-expert-health-insurance-advice-patients-uber-to-appointments"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/703de894e882d8a6da8c19964dc1ca71b969d30c-2000x1046.png?fit=crop&auto=format" alt="what we're reading logo" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 2nd 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-expanded-lung-cancer-screening-guidelines-expert-health-insurance-advice-patients-uber-to-appointments">What We’re Reading: Expanded Lung Cancer Screening Guidelines; Expert Health Insurance Advice; Patients Uber to Appointments</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/ajmc-staff">AJMC Staff</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-expanded-lung-cancer-screening-guidelines-expert-health-insurance-advice-patients-uber-to-appointments"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The American Cancer Society expanded eligibility for lung cancer screening; experts advised patients to do their research before choosing a plan from the Affordable Care Act’s insurance marketplaces; Republican-led states partnering with rideshare companies for medical appointment rides.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/osimertinib-combo-lessens-cns-progression-in-egfr-nsclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a56acbbdc6570b29acf1ac2ed733b60a00685cf2-3840x2160.jpg?fit=crop&auto=format" alt="Lung cancer cells | Image credit: David A Litman - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 1st 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/osimertinib-combo-lessens-cns-progression-in-egfr-nsclc">Osimertinib Combo Lessens CNS Progression in EGFR NSCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/darlene-dobkowski-ma">Darlene Dobkowski, MA</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/osimertinib-combo-lessens-cns-progression-in-egfr-nsclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Central nervous system (CNS) progression was reduced with osimertinib plus chemotherapy for patients with EGFR-mutated non-small cell lung cancer plus CNS metastases.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/adding-adjuvant-nivolumab-builds-on-standard-of-care-for-resectable-nsclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/33930ac2392d0877877bbbad5a8e2c170f33858d-1200x800.jpg?fit=crop&auto=format" alt="design of lungs with green, blue, and yellow colors" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 22nd 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/adding-adjuvant-nivolumab-builds-on-standard-of-care-for-resectable-nsclc">Adding Adjuvant Nivolumab Builds on Standard of Care for Resectable NSCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/laura-joszt">Laura Joszt, MA</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/adding-adjuvant-nivolumab-builds-on-standard-of-care-for-resectable-nsclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The results of CheckMate 77T showcase the improved event-free survival for patients with resectable non–small cell lung cancer who receive nivolumab in both the neoadjuvant and adjuvant setting and may have practice-changing implications. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-19"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/fda-grants-pembrolizumab-sixth-indication-in-nsclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/bf365d9c6f891c03e1fc1d99398a075dea15607e-3508x2480.jpg?fit=crop&auto=format" alt="Red FDA Approved stamp on a white backgroun" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 17th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/fda-grants-pembrolizumab-sixth-indication-in-nsclc">FDA Grants Pembrolizumab Sixth Indication in NSCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/laura-joszt">Laura Joszt, MA</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/fda-grants-pembrolizumab-sixth-indication-in-nsclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The anti–PD-1 agent pembrolizumab was granted a new indication to treat patients with resectable non–small cell lung cancer (NSCLC) as a neoadjuvant treatment with chemotherapy and continued as adjuvant treatment after surgery.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-school-nurse-shortage-keytruda-receives-fda-expansion-menthol-cigarette-flavored-cigar-ban"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/703de894e882d8a6da8c19964dc1ca71b969d30c-2000x1046.png?fit=crop&auto=format" alt="What We’re Reading: School Nurse Shortage; Keytruda Receives FDA Expansion; Menthol Cigarette, Flavored Cigar Ban" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 17th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-school-nurse-shortage-keytruda-receives-fda-expansion-menthol-cigarette-flavored-cigar-ban">What We’re Reading: School Nurse Shortage; Keytruda Receives FDA Expansion; Menthol Cigarette, Flavored Cigar Ban</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/ajmc-staff">AJMC Staff</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/what-we-re-reading-school-nurse-shortage-keytruda-receives-fda-expansion-menthol-cigarette-flavored-cigar-ban"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">School nurses play an overworked and understaffed role; Merck's immunotherapy Keytruda (pembroilzumab) has been granted approval for pre- and postsurgical treatment in lung cancer; the FDA is helping to curb tobacco-related health disparities.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/patients-with-distant-recurrent-nsclc-had-better-os-vs-those-with-de-novo-disease"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/9f975ae9c2ee542c6552c8d164ca16788f849a8b-5000x3750.jpg?fit=crop&auto=format" alt="3rd rendered medically accurate illustration of lung cancer Stock Illustration | © Adobe Stock" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 11th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/patients-with-distant-recurrent-nsclc-had-better-os-vs-those-with-de-novo-disease">Patients With Distant Recurrent NSCLC Had Better OS vs Those With De Novo Disease</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/patients-with-distant-recurrent-nsclc-had-better-os-vs-those-with-de-novo-disease"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Patients with distant recurrent non–small cell lung cancer (NSCLC) had significantly better overall survival (OS) than patients who had de novo disease.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/takeda-to-voluntarily-withdraw-mobocertinib-for-egfr-exon-20-insertion-nsclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/442fb3ee31b1218b821b8ba9b713726bae66abf5-1280x737.jpg?fit=crop&auto=format" alt="Hands holding a paper set of lungs | Image credit: SewcreamStudio - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 4th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/takeda-to-voluntarily-withdraw-mobocertinib-for-egfr-exon-20-insertion-nsclc">Takeda to Voluntarily Withdraw Mobocertinib for EGFR Exon 20 Insertion+ NSCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/kristi-rosa">Kristi Rosa</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/takeda-to-voluntarily-withdraw-mobocertinib-for-egfr-exon-20-insertion-nsclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Following discussions with FDA, Takeda will voluntarily withdraw mobocertinib in the United States for adult patients with EGFR exon 20 insertion mutation–positive, locally advanced or metastatic non–small cell lung cancer (NSCLC) based on the outcomes of the phase 3 EXCLAIM-2 trial.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/adjuvant-therapy-for-early-stage-nsclc-after-surgery-yields-lower-costs"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/f2470519bf4a5d739e4ffd6e213ea4c8833a15f8-1698x1131.jpg?fit=crop&auto=format" alt="Health Care Costs Stock Photos and Images - 123RF | © 123RF Stock Photos" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 26th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/adjuvant-therapy-for-early-stage-nsclc-after-surgery-yields-lower-costs">Adjuvant Therapy for Early-Stage NSCLC After Surgery Yields Lower Costs</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/adjuvant-therapy-for-early-stage-nsclc-after-surgery-yields-lower-costs"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Adjuvant therapy, instead of just surgery alone, for early-stage non-small-cell lung cancer (NSCLC) after surgery incurs lower medical costs than surgery alone.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/hr-nsclc-more-common-in-women-egfr-kras-more-common-in-hr-nsclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/79e063bbbcb49d153f1213e63312b1ab97912027-1200x900.jpg?fit=crop&auto=format" alt="DNA double helix molecules and chromosomes | © Adobe Stock" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 18th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/hr-nsclc-more-common-in-women-egfr-kras-more-common-in-hr-nsclc">HR+ NSCLC More Common in Women; EGFR, KRAS More Common in HR+ NSCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/hr-nsclc-more-common-in-women-egfr-kras-more-common-in-hr-nsclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Women have a higher likelihood of having hormone receptor (HR+) non-small cell lung cancer (NSCLC) than men, and mutations of EGFR and KRAS were more common in HR+ NSCLC in a recent study.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-25"></div></div></div><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/osimertinib-plus-chemotherapy-demonstrated-greater-pfs-benefit-in-patients-with-egfrm-advanced-nsclc-than-osimertinib-alone"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/36c9cc760549a177d5e20e8ce07f6a18ef239a6d-500x700.jpg?fit=crop&auto=format" alt="Dr. Pasi A. Jänne from the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute in Boston, Mass." width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 12th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/osimertinib-plus-chemotherapy-demonstrated-greater-pfs-benefit-in-patients-with-egfrm-advanced-nsclc-than-osimertinib-alone">Osimertinib Plus Chemotherapy Demonstrated Greater PFS Benefit in Patients With EGFRm Advanced NSCLC Than Osimertinib Alone</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/osimertinib-plus-chemotherapy-demonstrated-greater-pfs-benefit-in-patients-with-egfrm-advanced-nsclc-than-osimertinib-alone"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Osimertinib administered in addition to chemotherapy showed more progression-free survival (PFS) benefit than just osimertinib in patients with epidermal growth factor receptor–mutated (EGFRm) advanced non–small cell lung cancer (NSCLC).</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/patients-with-nsclc-describe-experiences-of-symptoms-on-daily-life"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/ea88dc7bff8216eb6f09503aa8387c0e4d55cd66-2048x1365.jpg?fit=crop&auto=format" alt="Woman Suffering an Anxiety Attack Alone in the Night Stock Photo | Image Credit iStockPhoto.com" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 12th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/patients-with-nsclc-describe-experiences-of-symptoms-on-daily-life">Patients With NSCLC Describe Experiences of Symptoms on Daily Life</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/patients-with-nsclc-describe-experiences-of-symptoms-on-daily-life"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Patients with advanced or metastatic non–small cell lung cancer (NSCLC) were able to specify a 1-point threshold when describing meaningful symptom change, for better or worse, that helped illustrate their symptom experience.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/liquid-biopsy-might-be-useful-in-the-detection-of-colorectal-lung-cancer"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/f1a9a005ba5be94ca7591ebb63388cb164411129-800x400.jpg?fit=crop&auto=format" alt="A graphic of a pair of lungs" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 6th 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/liquid-biopsy-might-be-useful-in-the-detection-of-colorectal-lung-cancer">Liquid Biopsy Might Be Useful in the Detection of Colorectal, Lung Cancer</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/liquid-biopsy-might-be-useful-in-the-detection-of-colorectal-lung-cancer"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Investigators wanted to analyze the diagnostic performance of methylation-sensitive restriction enzyme digestion followed by sequencing using cell-free DNA and explore the cancer signal origin of the cancer using DNN analyses for colorectal and lung cancers. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/elimination-of-pfts-might-worsen-disparities-for-african-american-patients-with-lung-cancer"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/aa4f637fea2cecc69666e40abde1bd8704484ef7-1280x853.jpg?fit=crop&auto=format" alt="A Black couple listens to a health care provider" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">September 3rd 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/elimination-of-pfts-might-worsen-disparities-for-african-american-patients-with-lung-cancer">Elimination of PFTs Might Worsen Disparities for African American Patients With Lung Cancer</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/elimination-of-pfts-might-worsen-disparities-for-african-american-patients-with-lung-cancer"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Removal of pulmonary function tests (PFTs) might exacerbate disparities for African American patients with lung cancer.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/certain-immune-cell-types-linked-with-ici-response-in-patients-with-nsclc"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/6efb64967c6fc91328f776ac70d0d8b22b948a42-1000x600.jpg?fit=crop&auto=format" alt="A scientist is adding blood to vials" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">August 22nd 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/certain-immune-cell-types-linked-with-ici-response-in-patients-with-nsclc">Certain Immune Cell Types Linked With ICI Response in Patients With NSCLC</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#000] text-sm italic" href="/authors/justina-petrullo">Justina Petrullo</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/certain-immune-cell-types-linked-with-ici-response-in-patients-with-nsclc"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Certain immune cell types are associated with immune checkpoint inhibitor (ICI) response in patients with non–small cell lung cancer (NSCLC).</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/perspectives-on-immunotherapy-in-the-treatment-of-advanced-nsclc-a-stakeholder-interchange-report"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/68f6092da49846c69f5cd86e58c93c2de4678fca-3840x2160.jpg?fit=crop&auto=format" alt="skeleton with lungs highlighted" width="288" class="jsx-ad50481d5ee26850 w-full xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 font-bold article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">August 21st 2023</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/perspectives-on-immunotherapy-in-the-treatment-of-advanced-nsclc-a-stakeholder-interchange-report">Perspectives on Immunotherapy in the Treatment of Advanced NSCLC: A Stakeholder Interchange Report</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/perspectives-on-immunotherapy-in-the-treatment-of-advanced-nsclc-a-stakeholder-interchange-report"></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div></div><div class="w-full text-center flex justify-center pb-24"><a class="px-4 py-2 border-y border-r bg-primary text-white" href="/compendium/lung-cancer?page=1">1</a><a class="px-4 py-2 border-y border-r " href="/compendium/lung-cancer?page=2">2</a><a class="px-4 py-2 border-y border-r " href="/compendium/lung-cancer?page=3">3</a><a class="px-4 py-2 border-y border-r " href="/compendium/lung-cancer?page=4">4</a><a class="px-4 py-2 border-y border-r " href="/compendium/lung-cancer?page=5">5</a><a class="px-4 py-2 border-y border-r " href="/compendium/lung-cancer?page=6">6</a><a class="px-4 py-2 border-y border-r " href="/compendium/lung-cancer?page=7">7</a><a class="px-4 py-2 border-y border-r " href="/compendium/lung-cancer?page=8">8</a><div class="px-4 py-2 border-y border-r">...</div><a class="px-4 py-2 border-y border-r" href="/compendium/lung-cancer?page=10">10</a><a class="px-4 py-2 border-y border-r" href="/compendium/lung-cancer?page=2">></a></div></div></div><div class="flex-none w-[300px] z-[9999] relative hidden md:block"><div style="top:5rem" class="sticky custom-spacing"><div class="collapse-container " style="overflow:hidden;max-height:900px;transition:max-height .4s ease-in-out"></div></div></div></div><div id="div-gpt-ad-pixel" style="width:1px;height:1px" class=""></div><noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-NK5KQXS" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript><div id="footerOuterWrap" class=" mx-auto flex"><div class="bg-[#00598D] xl:w-[70%] w-[70%] py-12 pl-auto"><div class="xxl:w-[75%] w-[90%] ml-auto"><div><span 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","_key":"8553da79b90f"}],"_type":"block","style":"normal","_key":"101679f26f1f"},{"_type":"block","style":"normal","_key":"d183c5f46b42","markDefs":[],"children":[{"marks":[],"text":"","_key":"0d26e04d0668","_type":"span"}]},{"children":[{"marks":["strong","underline"],"text":"Transcript","_key":"bada83fe6b55","_type":"span"}],"_type":"block","style":"normal","_key":"45499c03f4a6","markDefs":[]},{"style":"normal","_key":"9a2f5e608323","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Can you speak to the heterogeneity of lung cancer and why differentiation between subtypes is important?","_key":"57144b7bc21c0"}],"_type":"block"},{"_type":"block","style":"normal","_key":"59e5bf1b4cd8","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Historically, if you go back 30 years or so ago, we divided lung cancer into 2 major groups: non–small cell and small cell. 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","_key":"b1dbcee28ac9"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"3b1198c2c86d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"15ed704b9421"}]},{"children":[{"marks":[],"text":"Daly co-chaired ","_key":"945fefa3a185","_type":"span"},{"_type":"span","marks":["em"],"text":"The American Journal of Managed Care","_key":"11e91cf16c04"},{"_key":"7cf143307b06","_type":"span","marks":["superscript"],"text":"®"},{"_type":"span","marks":[],"text":"’s Institute for Value-Based Medicine","_key":"00f2f158419a"},{"text":"®","_key":"ab5e59259d07","_type":"span","marks":["superscript"]},{"_key":"ff87f93c1791","_type":"span","marks":[],"text":" held on November 2 in New York City, where presenters discussed at-home and remote cancer treatments. He is a thoracic oncologist who specializes in lung cancer, as well as a health services researcher interested in innovative cancer care systems."}],"_type":"block","style":"normal","_key":"e78d60852899","markDefs":[]},{"_type":"block","style":"normal","_key":"aaabdbfa6ae1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"38689747582c"}]},{"style":"normal","_key":"4523c44c26c4","markDefs":[],"children":[{"marks":["strong","underline"],"text":"Transcript","_key":"f6cfdc32d367","_type":"span"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Could you explain how at-home or remote treatment methods have affected your delivery of care to patients?","_key":"90ea780440520"}],"_type":"block","style":"normal","_key":"4c3d15782e41"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"1dafcbe75a39"}],"_type":"block","style":"normal","_key":"d39f6fa99881"},{"style":"normal","_key":"2407a6189887","markDefs":[],"children":[{"_type":"span","marks":[],"text":"A prime example of these new treatment methods is a pilot study we have ongoing right now at my institution where we're looking at the adoption of extended dosing of immunotherapy for patients with lung cancer. How we deliver that safely is by scheduling a televisit in between their infusional doses in order to do a toxicity check and ensure that they're tolerating the treatments safely. ","_key":"dc1685319bd80"}],"_type":"block"},{"style":"normal","_key":"0fb7f72af80d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"cfb7405a1ea5"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"These visits would otherwise have required those patients to come into the clinic in order to have that done. Now, we're able to do labs at the home and a televisit and provide that same service to ensure that they're getting their care safely. ","_key":"7482d97c36f7"}],"_type":"block","style":"normal","_key":"32c19519d2a2"},{"style":"normal","_key":"8e9fcdc0a689","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"94229a3588ee"}],"_type":"block"},{"markDefs":[],"children":[{"marks":[],"text":"So, what does that mean for patients? It means rather than having to come in every 3 weeks, they can now come in every 6 weeks. For patients who are working, for patients who have travel plans, for patients who have dependents that they're taking care of, this has had a huge impact on their quality of life.","_key":"d9d22807421c","_type":"span"}],"_type":"block","style":"normal","_key":"b7274aafeb26"},{"_type":"block","style":"normal","_key":"c335f4f9de74","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"e9041eb7de49"}]},{"_type":"block","style":"normal","_key":"8c8f542539e0","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"In the future, what innovations or changes in lung cancer treatment do you anticipate to have the most significant impact on patient outcomes?","_key":"90c648ba15810"}]},{"children":[{"marks":[],"text":"","_key":"411475a0e8ce0","_type":"span"}],"_type":"block","style":"normal","_key":"8537811e5c6a","markDefs":[]},{"_key":"121b52d99f73","markDefs":[],"children":[{"marks":[],"text":"Well, one area where I'm really excited, and that ties together well with the virtual care, is subcutaneous immunotherapies. 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It's called the CALGB 140503 trial, and I have to give a major shoutout to Dr. Altorki, who was really the heart and soul of this trial and helped it to come to fruition. ","_key":"57753075f4a90"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"ffe2fc19eb15","markDefs":[],"children":[{"_key":"bc8717c2e0ec","_type":"span","marks":[],"text":""}]},{"_key":"e7e1ba8e4eeb","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The inspiration behind this was we're finding cancers that are smaller and smaller, our CT scans are getting better and better, we're finding subsolid lesions. The idea of taking out an entire lobe for something that sometimes comes back as just a couple of millimeters of invasive cancer really didn't feel like we're doing the right thing for patients. The historic precedent was always that we needed to do a lobectomy, and there were actually even trials establishing that as the definitive treatment from the Lung Cancer Study Group back in 1995.","_key":"0169157d8eec"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"821e92223b37","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"1329414bed5e0"}]},{"_type":"block","style":"normal","_key":"00befec4b4a8","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Dr. Altorki put this really thoughtful trial together. He took tumors that were 2 centimeters or less with pathologically staged mediastinals. We had to actually sample 2 and 2 lymph node stations, and 1 and 1 lymph node station and send that all to pathology while the patient was on the operating table, and they would measure our tumor, they would check to make sure our lymph nodes were negative, and then we'd call them, and the patients were randomized to a lobar or sublobar resection. ","_key":"d267eb03ff660"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"27e4d1df29c7"}],"_type":"block","style":"normal","_key":"0dc70715a8b6"},{"style":"normal","_key":"385fbf7fa001","markDefs":[],"children":[{"_type":"span","marks":[],"text":"For the patients who were having a sublobar resection, that means anything less than a lobe, so that could be a wedge resection, or a segmentectomy, and that was left up to the treating surgeon. What they looked for is a couple of different things. One, they wanted to look at surgical outcomes. Are we doing both types of surgery very safely? Are we having equal length of stays, equal morbidity, equal mortality? Two, how did this impact pulmonary function? That’s one of the big quality of life pieces for patients, how well are they breathing after these surgeries?","_key":"0e3e7f6f3984"}],"_type":"block"},{"_type":"block","style":"normal","_key":"0d7dddd96ac1","markDefs":[],"children":[{"text":"","_key":"a5fcc408de880","_type":"span","marks":[]}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Then, they looked at their long-term outcomes, so disease-free survival, overall survival, then recurrence, and pattern of recurrence. 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I'm a robotic surgeon. I love robotics. I spend a lot of my time actually working with engineers to build new robots, to build new robotic devices, new instruments, and it has been one of the joys of my career to help start up a robotics program.","_key":"bfa1e6302f340"}],"_type":"block","style":"normal","_key":"6b4d215ca1ce"},{"_key":"dacf40fcdc34","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"ac3c096ca23b0"}],"_type":"block","style":"normal"},{"_key":"dad1fd55f76d","markDefs":[],"children":[{"_key":"ccbbf86096f40","_type":"span","marks":[],"text":"Some of the advantages that I think, in general, when I think about minimally invasive—and that can include fats, and that can include robotics—is that we're making smaller incisions on patients. Many studies have helped to establish that patients who have these smaller incisions where we're not having to put retractors in their chest, we're not having to shingle their ribs, have less pain. They're staying in the hospital for shorter periods of time, we're not seeing any difference in other morbidities, so atrial fibrillation rates, things like that, which is great. And we can perform the surgeries really safely. So it’s safe, less painful, and we can get patients home sooner, which to me is a huge win."}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"7a6a923ec0cf","markDefs":[],"children":[{"_key":"a022d3d313630","_type":"span","marks":[],"text":""}]},{"style":"normal","_key":"1e8a7e7ac15a","markDefs":[],"children":[{"text":"One of the other huge advantages, in my opinion, when we think about doing minimally invasive procedures, especially when I think about robotics, is I have a 3D viewer, which is incredible. I'm able to zoom in on the anatomy a huge amount to be able to help with the conduct of the surgery, and we have so much mobility and flexibility with the wrists. They basically replicate the movements of human hands in a miniaturized version. This is basically like having a miniaturized version of \"Honey, I Shrunk the Kids\" style in your chest doing your surgery, which is really extraordinary.","_key":"878da1b9104b0","_type":"span","marks":[]}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"78c35f78c8b50"}],"_type":"block","style":"normal","_key":"adf4d430df27"},{"style":"normal","_key":"cd1fd061a622","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The technology has continued to advance over time to allow us to do more and more complex cases. We have seen this huge increase in minimally invasive surgeries, really, in particular, over the last decade, led by a lot of just really extraordinary teachers and master surgeons around the country who have been going around training people, all of our wonderful mentors, including those that I had, who trained me and my training and allowed me to go out and perform all these surgeries.","_key":"6d8880ec861e0"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"a86eafe7320a0"}],"_type":"block","style":"normal","_key":"2acacdf0429d"},{"style":"normal","_key":"315749043fe4","markDefs":[],"children":[{"_type":"span","marks":[],"text":"We're seeing a huge increase, but we're also seeing an increase in the complexity. We're doing pneumonectomies, sleeve resections, tracheal reconstructions, all sorts of really complex surgery, now minimally invasively, as we've been able to increase our comfort level, our skills, and as the technology has continued to get better.","_key":"49c8a13159570"}],"_type":"block"},{"children":[{"marks":[],"text":"","_key":"59f27b30bf840","_type":"span"}],"_type":"block","style":"normal","_key":"92f4a08cffaa","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"The other big piece to this, and sort of the opposite end where we talked a little bit before about sort of ","_key":"7a93bd4f2a140"},{"_key":"268c911adf27","_type":"span","marks":["05d2468822d0"],"text":"tissue being a big issue"},{"_type":"span","marks":[],"text":", we've seen a huge expansion in some of the tools that our interventional pulmonologists that we as thoracic surgeons also use, and that's in the form of bronchoscopy. 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So, it's been a really exciting space for all of us.","_key":"bec595ecb8330"}],"_type":"block","style":"normal"},{"style":"normal","_key":"13018e03fd73","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"bd242da6627c0"}],"_type":"block"},{"_key":"6f87e43a05c1","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"What are you currently most excited about in the lung cancer space?","_key":"811999c547990"}],"_type":"block","style":"normal"},{"_key":"0798bf73bb6e","markDefs":[],"children":[{"text":"","_key":"a0c11a42eb8f0","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"_key":"9b99e4a060b1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"I'm excited about everything. 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One of the old adages we like to say all the time is \"tissue is the issue,\" but I think I mean that more than ever right now. Because now when we're thinking about making a new lung cancer diagnosis, not only do we want to know the histology—so we want a diagnosis, we want a histology—but we also want the opportunity to do things like PD-L1 (programmed cell death ligand 1) testing, molecular testing, because immunotherapy is not the right answer for everybody. We have other molecular alterations, targetable mutations, that have dedicated therapies for them.","_key":"be7b11346b020"}],"_type":"block","style":"normal","_key":"f3638f981e93","markDefs":[]},{"markDefs":[],"children":[{"_key":"573b2660038c0","_type":"span","marks":[],"text":""}],"_type":"block","style":"normal","_key":"8d322272cd94"},{"_type":"block","style":"normal","_key":"96ff03ca6739","markDefs":[],"children":[{"_key":"553da252badb0","_type":"span","marks":[],"text":"I think about, in particular, a treatment like osimertinib for our patients who are eGFR (epidermal growth factor receptor) positive. There are 2 primary mutations that we use osimertinib for—that's the L858R mutation and the Exon 19 deletion. We already know that that's very, very efficacious in the adjuvant setting based on the ADAURA trial. We hardly ever have disease-free survival and overall survival curves like we did in that trial. In fact, the trial was stopped early because there was such a benefit in that treatment arm."}]},{"style":"normal","_key":"2269caf7bcf7","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"dfd34fcedac60"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The NeoADAURA trial is actually ongoing to help establish the efficacy of that treatment in the neoadjuvant space. One of the things that's sort of unique about some of these mutations is some of them tend to be very immunologically cooled. So, what do I mean by that? Well, immunotherapy doesn't work particularly well for them.","_key":"37e76d0937f00"}],"_type":"block","style":"normal","_key":"eb97bc9b1b73"},{"style":"normal","_key":"8f6c9c0e794d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"8030f628f344"}],"_type":"block"},{"style":"normal","_key":"1bf71974a976","markDefs":[],"children":[{"_key":"6fc353b82dbe","_type":"span","marks":[],"text":"One of the really common mutations that I think about for that is the Exon 19 deletion. If we're not testing for that ahead of time, if we don't know that ahead of time, and then we're putting this patient on immunotherapy, not only are we giving them potential risks without benefit, but we're also potentially affecting their ability to get the therapy that's really going to give them the best outcome, which is the osimertinib."}],"_type":"block"},{"style":"normal","_key":"2ebf1bd65030","markDefs":[],"children":[{"marks":[],"text":"","_key":"4cb4c29f4a8b0","_type":"span"}],"_type":"block"},{"markDefs":[],"children":[{"marks":[],"text":"It's really important that we do 2 different things. One, we have to get enough tissue to make sure that we understand the right treatment regimens for that patient. If that's not something that we can get ahead of time with just a biopsy, that's where all of us are starting to say, “Okay, so maybe that's a patient we don't think about neoadjuvant therapy for; we get a good resection on them, and then we give them an adjuvant to make sure that we're getting them the right therapy.”","_key":"fde701bac2390","_type":"span"}],"_type":"block","style":"normal","_key":"4ad9d07853b5"},{"_type":"block","style":"normal","_key":"e6bcdf1bf052","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"f6c41b5449580"}]},{"_type":"block","style":"normal","_key":"f9aba875e80a","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The other piece to this is making sure we get the testing in a timely fashion. To that end, working within our teams, working with our pathology colleagues to say, “Okay, we need to get this testing back as fast as possible. So ,as soon as you have that new lung cancer diagnosis, we need to get that PD-L1 testing, we need to get the molecular testing sent off.”","_key":"7ef2bb6b0d820"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"fe159fb26e640"}],"_type":"block","style":"normal","_key":"0c38d8de8ab0"},{"markDefs":[],"children":[{"_key":"eab0625dee5f0","_type":"span","marks":[],"text":"Most places aren't lucky enough to be able to do that in house, and it takes a few weeks to get it back. 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Gillaspie is a faculty member of VUMC’s Department of Thoracic Surgery and an assistant professor of thoracic surgery. She also presented at ","_key":"406c489309bc"},{"_type":"span","marks":["em"],"text":"The American Journal of Managed Care","_key":"bc18785920af1"},{"_type":"span","marks":["superscript"],"text":"®","_key":"bc18785920af2"},{"marks":[],"text":"’s Institute for Value-Based Medicine","_key":"455ec6cea554","_type":"span"},{"_type":"span","marks":["superscript"],"text":"®","_key":"14613ef3fce5"},{"text":" held in Nashville, Tennessee, on August 17, 2023.","_key":"20938b29b66a","_type":"span","marks":[]}],"_type":"block"},{"_type":"block","style":"normal","_key":"bb95e8074766","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"4a54952765fb0"}]},{"_type":"block","style":"normal","_key":"d77dc620c390","markDefs":[],"children":[{"text":"Transcript","_key":"ea0896b4fc2f0","_type":"span","marks":["strong","underline"]}]},{"style":"normal","_key":"0a3e87eaa61f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"db0430115c450"}],"_type":"block"},{"markDefs":[],"children":[{"marks":["strong"],"text":"What are traditional lung cancer outcomes and how have they been improving?","_key":"e4f38c8db4420","_type":"span"}],"_type":"block","style":"normal","_key":"487769124e25"},{"style":"normal","_key":"4dd58d250330","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"dfda5121c4990"}],"_type":"block"},{"style":"normal","_key":"fcca13237f07","markDefs":[],"children":[{"_type":"span","marks":[],"text":"There's a couple of things to know about lung cancer. I think, first and foremost, it impacts a huge number of people. Most people are somehow impacted by cancer, and, in particular, lung cancer. So it’s very, very common. We see it as one of our top 3 every single year in both men and women, but the other really important thing to note is it's a particularly lethal cancer.","_key":"9fd8280e37b90"}],"_type":"block"},{"_key":"c27e1adf0919","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"a32cbb91a73c0"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"17a42df98c42","markDefs":[],"children":[{"_type":"span","marks":[],"text":"When we think about cancers, we think about sort of our mortality and our survival. Lung cancer, unfortunately, historically, has always scored really poorly. Our 5-year survival is nowhere near where any of us wants it to be, and we've seen really big improvements in some of the other cancer types. So, breast and colon, where we've seen a huge amount of wonderful research, and funding for that research help to make massive advances. Lung cancer is a little lagging behind, but we're now starting to get some great momentum in that space as well. It's important to know that lung cancer remains the number 1 cancer killer.","_key":"386d7d16ebb00"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"7eac439c1fc30"}],"_type":"block","style":"normal","_key":"a554fba5f8b9"},{"markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.cancer.gov/types/lung/research/nlst","_key":"62b591f638f4"}],"children":[{"_type":"span","marks":[],"text":"So, what are some of the big changes that we see that's having a huge impact on that? Well, I think one of the most important things to talk about is the NLST, so ","_key":"ebeca4fc4faf0"},{"_type":"span","marks":["62b591f638f4"],"text":"the National Lung Screening Trial.","_key":"ebf6347fbb04"},{"_type":"span","marks":[],"text":" That was an incredible trial that helped us to usher in an era of lung cancer testing in which we're allowed to test people without lung cancer who are high risk for lung cancer and do screening for that.","_key":"13f57055de20"}],"_type":"block","style":"normal","_key":"1afd55039362"},{"_type":"block","style":"normal","_key":"c1ac2d3aaa7f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"5f1880d63f440"}]},{"children":[{"_type":"span","marks":[],"text":"We know about screening in a lot of other cancer types, right? We do mammograms for breast cancer screening, we do colonoscopies for colon cancer screening, we do pap smears, but for a long time, we actually had nothing in lung cancer, because chest x-rays really actually weren't helping us to catch things sooner and faster. This brilliant trial came out looking at the use of low-dose CT scans that's using about the same amount of radiation as a chest X ray but in CT scan format. It allows us to see the lungs much more clearly in much greater detail to try to identify cancers sooner.","_key":"cb9c40bb99210"}],"_type":"block","style":"normal","_key":"63d1b0954827","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"07f1e308031f0"}],"_type":"block","style":"normal","_key":"8f056453b7b4"},{"style":"normal","_key":"dcd173c44054","markDefs":[],"children":[{"_type":"span","marks":[],"text":"For people who are higher risk, what category of people is that? So, it’s people 50 to 80 who have at least 20-year pack-year smoking history who are current smokers or who have quit sort of within the last 15 years. For those folks, we’re able to do lung cancer screening. Our primary care doctors are so wonderful about asking patients about it, but we really want our patients as well to be asking, “Do I meet the criteria for this?” It's a great opportunity to define things sooner.","_key":"f259dec4361c0"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"013af927ff850"}],"_type":"block","style":"normal","_key":"3886b8fe835c"},{"_type":"block","style":"normal","_key":"f81b00b1f2ec","markDefs":[],"children":[{"marks":[],"text":"Since we've started developing lung cancer screening programs around the country, we've started to see a change in when we're diagnosing lung cancer. Most lung cancer is diagnosed in stage IV, and that's because most people don't have any symptoms when they have lung cancer. Usually, a cancer has to get pretty big or be in a particular location before people start having symptoms from it, so this allows us to catch up before those symptoms. We're starting to see a little bit of a shift, we call it a stage shift, so more people getting caught in that stage I, and that has a huge impact on survival.","_key":"3cea56f085800","_type":"span"}]},{"markDefs":[],"children":[{"marks":[],"text":"","_key":"837935dc040c0","_type":"span"}],"_type":"block","style":"normal","_key":"5e2dada9f140"},{"children":[{"_type":"span","marks":[],"text":"We're also living in an immunotherapy and molecular era, and it is so exciting, [that] all of these new therapies are being developed to specifically target some of the mutations in cancer, to help leverage the immune system to attack cancer. With the advent of some of these therapies, we're also seeing that needle move, and for the first time in a long time, we're seeing our 5-year survival for kind of the whole spectrum of lung cancer improve, and so that's really, really exciting for us.","_key":"a478f4d8eab80"}],"_type":"block","style":"normal","_key":"dcac70c71f61","markDefs":[]}],"title":"Dr Erin Gillaspie Discusses Lung Cancer Outcome Improvements","authorMapping":[{"_type":"author","_updatedAt":"2025-01-08T16:42:13Z","url":{"current":"brooke-mccormick","_type":"slug"},"firstName":"Brooke","lastName":"McCormick","authorType":"author","displayName":"Brooke McCormick","_rev":"A9UM2QVfJg2GpKiBNGLBGh","_id":"00af9d05-a2c4-4451-a6d1-0e28b08cbb65","biography":[{"style":"normal","_key":"936ecf4b7f0c","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Brooke is an associate editor for ","_key":"8d68730a8da0"},{"_type":"span","marks":["em"],"text":"The American Journal of Managed Care","_key":"730c46c984c9"},{"_type":"span","marks":[],"text":"® (","_key":"0b218fbaa571"},{"_type":"span","marks":["em"],"text":"AJMC","_key":"b1b5b3d9cff0"},{"_key":"7de919198f04","_type":"span","marks":[],"text":"®). 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Socinski, MD, executive director at AdventHealth Cancer Institute, shares insight on the cost-effectiveness and utility of biomarker testing in non–small cell lung cancer (NSCLC). ","_key":"0f1724f73d6f"}]},{"markDefs":[],"children":[{"text":"Transcript","_key":"ca9320690521","_type":"span","marks":["strong","underline"]}],"_type":"block","style":"normal","_key":"161e78469543"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Coverage of biomarker testing has often lagged behind research advances. What should managed care leaders know about the testing landscape overall?","_key":"fc71e0421940"}],"_type":"block","style":"normal","_key":"781f34b58e56"},{"_key":"18b864d56a90","markDefs":[],"children":[{"_type":"span","marks":[],"text":"I think managed care companies need to understand that our job and their job should really be focused on getting the right treatment to the right patient at the right time—and that's been demonstrated to be cost-effective. 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","_key":"7c0d77535fa7","_type":"span"}],"_type":"block"},{"children":[{"_type":"span","marks":[],"text":"","_key":"a8ecf298131c"}],"_type":"block","style":"normal","_key":"e0d4fdb08790","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["strong","underline"],"text":"Transcript","_key":"ebaf72bf7f12"}],"_type":"block","style":"normal","_key":"91e635560b34"},{"style":"normal","_key":"a37d31e274c7","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"How do you approach the issue of drug resistance in patients with NSCLC in your clinical practice?","_key":"9e6ea5a76c270"}],"_type":"block"},{"style":"normal","_key":"4eba876fea83","markDefs":[],"children":[{"_type":"span","marks":[],"text":"We've developed a whole new generation of first-line drugs that are highly effective—but, particularly in the arena of targeted therapies, we know that at some point, acquired resistance is going to happen. 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