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vertical; } </style></div><main class="main-wrapper"><section class="poster_backgroundvideo products"><div class="page-padding"><div class="conferences-container w-container"><div class="home-services-component"><div class="hero-component"><div class="hero-wrapper"><h1 class="main-header margin-bottom hero-main">Designed for Cell Therapy Processes</h1><div class="hero-sub">The Vertical-Wheel<sup>®</sup> bioreactor family provides robust, scalable, and flexible performance for any stage of cell manufacturing.</div></div></div></div></div></div></section><section class="section-services-overview"><div class="page-padding"><div class="conferences-container w-container"><div class="quote-overview-component"><div class="service-overview-wrapper section-revolutionary"><div class="sub-hero-header">Single-Use Systems for All Your Scale Up Needs</div><div class="heading-large sub-paragraph">From small scale process development to large scale clinical and commercial production, Vertical-Wheel bioreactors are the enabling technology for allogeneic cell therapies. All bioreactors, including product contact materials and software, are manufactured to meet or exceed cGMP quality and regulatory standards.</div></div></div></div></div></section><section class="section-product"><div class="page-padding"><div class="conferences-container w-container"><div class="product-component"><div class="product-wrapper"><div class="main-product-comtainer"><div class="main-product-container-info"><h2 class="margin-bottom-margin-small">PBS-0.1 Mini Vertical-Wheel Bioreactor</h2><p class="product-info-detail">The entry-level tool for representative process development 0.1 L maximum working volumes available.</p><div class="product-button-wrapper"><a href="https://www.pbsbiotech.com/pbs-01-mini-bioreactors" class="mg-button w-button">Learn More</a></div></div><div class="main-product-container-pic"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6740f9c0d4e7840cdc0cb2d0_01-sq.png" loading="lazy" width="250" height="Auto" alt=" PBS-0.1 Mini Vertical-Wheel Bioreactor" class="responsive"/></div></div><div class="main-product-comtainer-copy"><div class="main-product-container-info"><h2 class="margin-bottom-margin-small">PBS-0.5 Mini Vertical-Wheel Bioreactor</h2><p class="product-info-detail">The entry-level tool for representative process development 0.5 L maximum working volumes available.</p><div class="product-button-wrapper"><a href="https://www.pbsbiotech.com/pbs-05-mini-bioreactors" class="mg-button w-button">Learn More</a></div></div><div class="main-product-container-pic"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6740fa78d5fce5344c225a70_03-sq.png" loading="lazy" width="250" height="Auto" alt=" PBS-0.5 Mini Vertical-Wheel Bioreactor" class="responsive"/></div></div><div class="main-product-comtainer-copy"><div class="main-product-container-info"><h2 class="margin-bottom-margin-small">PBS-3 Vertical-Wheel Bioreactor</h2><p class="product-info-detail">Take your process development to the next level with this full feature bioreactor. 3L maximum working volume.</p><div class="product-button-wrapper"><a href="https://www.pbsbiotech.com/pbs-3-bioreactors" class="mg-button w-button">Learn More</a></div></div><div class="main-product-container-pic"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6740fad7d5fce5344c22a7e5_03-final-sq.png" loading="lazy" width="250" height="Auto" alt=" PBS-3 Vertical-Wheel Bioreactor" class="responsive"/></div></div><div class="main-product-comtainer-copy"><div class="main-product-container-info"><h2 class="margin-bottom-margin-small">PBS-15 Vertical-Wheel Bioreactor</h2><p class="product-info-detail">Continue your cell culture process scale up for clinical stage production. 15L maximum working volume.</p><div class="product-button-wrapper"><a href="https://www.pbsbiotech.com/pbs-15-bioreactors" class="mg-button w-button">Learn More</a></div></div><div class="main-product-container-pic"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6740fe5f1d740c08247c7275_15-left-sq.png" loading="lazy" width="250" height="Auto" alt=" PBS-15 Vertical-Wheel Bioreactor" class="responsive"/></div></div><div class="main-product-comtainer-copy"><div class="main-product-container-info"><h2 class="margin-bottom-margin-small">PBS-80 Vertical-Wheel Bioreactor</h2><p class="product-info-detail">Prepare for commercial-scale manufacturing of your cell therapy products. 80L maximum working volume.</p><div class="product-button-wrapper"><a href="https://www.pbsbiotech.com/pbs-80-bioreactors" class="mg-button w-button">Learn More</a></div></div><div class="main-product-container-pic"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6740fc9a3b83064df09497e5_80-sq.png" loading="lazy" width="250" height="Auto" alt=" PBS-80 Vertical-Wheel Bioreactor" class="responsive"/></div></div></div></div></div></div></section><section class="section-tabs"><div class="page-padding"><div class="conferences-container w-container"><div class="tabs-component"><h2 class="product-resources-header">Vertical-Wheel Bioreactor Components</h2><div data-current="Tab 1" data-easing="ease" data-duration-in="300" data-duration-out="100" class="tabs w-tabs"><div class="tabs-menu w-tab-menu"><a data-w-tab="Tab 1" class="tab-link w-inline-block w-tab-link w--current"><div class="text-system-features">Electromechanical Housing</div></a><a data-w-tab="Tab 2" class="tab-link w-inline-block w-tab-link"><div class="text-system-features">Single-Use Vessel</div></a><a data-w-tab="Tab 3" class="tab-link w-inline-block w-tab-link"><div class="text-system-features">Propietary Software</div></a></div><div class="w-tab-content"><div data-w-tab="Tab 1" class="w-tab-pane w--tab-active"><div class="tabs-content-wrapper"><div class="tabs-content-left"><div class="content-list-wrapper"><p class="text-size-medium margin-bottom margin-small">Electromechanical Housing Features</p><ul role="list" class="tab-list"><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Stainless steel construction with minimal footprint</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Simple connection of gas lines and mass flow controllers for gas intake and filtered output</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Integrated touchscreen user interface for customizable process control</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Adjustable height harvest valve for rapid harvest or medium exchange (PBS-15 and PBS-80 only)</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Safety interlocks for emergency process stop, fluid spill catch, and remote alerts</li></ul></div></div><div id="w-node-_9c885972-d86f-3f36-3a1f-d682246b0602-3517ba48" class="tabs-image-wrapper"><img sizes="(max-width: 479px) 100vw, (max-width: 767px) 82vw, (max-width: 991px) 70vw, 300px" height="" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy.jpg" srcset="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy-p-500.jpg 500w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy-p-800.jpg 800w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy-p-1080.jpg 1080w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy-p-1600.jpg 1600w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy-p-2000.jpg 2000w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy-p-2600.jpg 2600w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62deea85397dcd1fea0b1c08_WS%20-%20213%20copy-p-3200.jpg 3200w" alt="" class="tabs-image"/></div></div></div><div data-w-tab="Tab 2" class="w-tab-pane"><div class="tabs-content-wrapper"><div class="tabs-content-left"><div class="content-list-wrapper"><p class="text-size-medium margin-bottom margin-small">Single-Use Vessel Features</p><ul role="list" class="tab-list"><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Injection-molded plastics: polycarbonate (Vertical-Wheel impellers, vessels for PBS Minis and PBS-3) or PVDF (vessels for PBS-15 and PBS-80)</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Product contact materials meet or exceed requirements for USP Class VI Testing for <br/>Plastics <88> and/or ISO 10993<br/></li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Embedded magnets allow for coupled rotation of impeller with no axle penetration</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Sterile access ports for single-use or reusable sensors, sampling, and harvesting tubes</li></ul></div></div><div id="w-node-b729a6b5-1d7d-87c5-7d49-c66aabc9605e-3517ba48" class="tabs-image-wrapper"><img sizes="(max-width: 479px) 100vw, (max-width: 767px) 82vw, 100vw" srcset="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/63bbe87be91f6600684d28f4_Mini%20-%200.5L%20vessel%20orth-p-500.jpg 500w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/63bbe87be91f6600684d28f4_Mini%20-%200.5L%20vessel%20orth-p-800.jpg 800w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/63bbe87be91f6600684d28f4_Mini%20-%200.5L%20vessel%20orth-p-1080.jpg 1080w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/63bbe87be91f6600684d28f4_Mini%20-%200.5L%20vessel%20orth-p-1600.jpg 1600w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/63bbe87be91f6600684d28f4_Mini%20-%200.5L%20vessel%20orth.jpg 1814w" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/63bbe87be91f6600684d28f4_Mini%20-%200.5L%20vessel%20orth.jpg" loading="lazy" alt="" class="tabs-image"/></div></div></div><div data-w-tab="Tab 3" class="tab-pane-tab-3 w-tab-pane"><div class="tabs-content-wrapper"><div id="w-node-_5a162b66-62ed-1646-bf31-dd7ca21c8e79-3517ba48" class="tabs-content-left"><div class="content-list-wrapper"><p class="text-size-medium margin-bottom margin-small">Proprietary Software Features</p><ul role="list" class="tab-list"><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Simple and customizable programming for control of cell culture process parameters</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Autopilot feature controls pumps based on real-time feedback from sensors</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Can be used to meet 21 CFR Part 11 cGMP requirements for security and history of user access</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Recorded audit trail and process data backup to local or network drive</li><li class="heading-xsmall text-color-blue margin-bottom margin-xsmall">Options for wireless process control and alarm reporting</li></ul></div></div><div id="w-node-_5a162b66-62ed-1646-bf31-dd7ca21c8e9a-3517ba48" class="tabs-image-wrapper"><img sizes="(max-width: 479px) 100vw, (max-width: 767px) 82vw, 100vw" srcset="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/633b78940c2bf78438e16d2a_Prod%20-%20sys%20feat%20screen2-p-500.jpg 500w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/633b78940c2bf78438e16d2a_Prod%20-%20sys%20feat%20screen2-p-800.jpg 800w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/633b78940c2bf78438e16d2a_Prod%20-%20sys%20feat%20screen2-p-1080.jpg 1080w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/633b78940c2bf78438e16d2a_Prod%20-%20sys%20feat%20screen2-p-1600.jpg 1600w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/633b78940c2bf78438e16d2a_Prod%20-%20sys%20feat%20screen2-p-2000.jpg 2000w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/633b78940c2bf78438e16d2a_Prod%20-%20sys%20feat%20screen2.jpg 2459w" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/633b78940c2bf78438e16d2a_Prod%20-%20sys%20feat%20screen2.jpg" loading="lazy" alt="" class="tabs-image"/></div></div></div></div></div></div></div></div></section><section class="section-product-detail hide"><div class="page-padding"><div class="conferences-container w-container"><div class="product-detail-component"><h2 class="pbs-product-line-heading">PBS Product line</h2><h3 class="product-resources-header">Start small and we grow with your business</h3><div class="product-line-list-wrapper w-dyn-list"><div role="list" class="product-line-list w-dyn-items"><div role="listitem" class="w-dyn-item"><div class="product-detail-category"><div><img alt="" loading="lazy" width="151" src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/6317984995a9ee62cc78cb33_mini.jpg" class="product-line-image"/></div><h3 class="text-color-black text-align-center margin-top margin-medium stretch">PBS-Mini</h3></div></div><div role="listitem" class="w-dyn-item"><div class="product-detail-category"><div><img alt="" loading="lazy" width="151" src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/6317985a209d2d1d6a0128b1_3mag.jpg" class="product-line-image"/></div><h3 class="text-color-black text-align-center margin-top margin-medium stretch">PBS-3</h3></div></div><div role="listitem" class="w-dyn-item"><div class="product-detail-category"><div><img alt="" loading="lazy" width="151" src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/63179862c5a1a8689fee535e_15mag.jpg" class="product-line-image"/></div><h3 class="text-color-black text-align-center margin-top margin-medium stretch">PBS-15</h3></div></div><div role="listitem" class="w-dyn-item"><div class="product-detail-category"><div><img alt="" loading="lazy" width="151" src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/6317986f2ce6ec52e392bf3f_80mag.jpg" class="product-line-image"/></div><h3 class="text-color-black text-align-center margin-top margin-medium stretch">PBS-80</h3></div></div></div></div><div class="w-dyn-list"><div role="list" class="w-dyn-items"><div role="listitem" class="w-dyn-item"><div class="product-list"><div id="w-node-_18038298-799e-fac3-6c8e-4248fe7e01fd-3517ba48" class="product-list-left"><h2 class="margin-bottom margin-small">PBS-Mini</h2><div class="product-description"><p class="text-color-blue">The entry-level tool for representative process development. 0.1 and 0.5 L maximum working volumes available.</p></div><div class="product-line-button-wrapper"><a href="/products/pbs-mini" class="product-info-button w-button">Product info</a><a href="#" class="download-button w-button">Download manual</a></div></div><div class="product-list-right"><img src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/62def5a823fb57451baf538b_PBS%20Minis%20(0.1%20%26%200.5L).png" loading="lazy" alt="" sizes="(max-width: 479px) 0px, 100vw" srcset="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/62def5a823fb57451baf538b_PBS%20Minis%20(0.1%20%26%200.5L)-p-500.png 500w, https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/62def5a823fb57451baf538b_PBS%20Minis%20(0.1%20%26%200.5L).png 563w"/></div></div></div><div role="listitem" class="w-dyn-item"><div class="product-list"><div id="w-node-_18038298-799e-fac3-6c8e-4248fe7e01fd-3517ba48" class="product-list-left"><h2 class="margin-bottom margin-small">PBS-3</h2><div class="product-description"><p class="text-color-blue">Take your process development to the next level with this full feature bioreactor. 3L maximum working volume.</p></div><div class="product-line-button-wrapper"><a href="/products/pbs-3" class="product-info-button w-button">Product info</a><a href="#" class="download-button w-button">Download manual</a></div></div><div class="product-list-right"><img src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/62def57902b645484875fe7e_PBS%203L.png" loading="lazy" alt=""/></div></div></div><div role="listitem" class="w-dyn-item"><div class="product-list"><div id="w-node-_18038298-799e-fac3-6c8e-4248fe7e01fd-3517ba48" class="product-list-left"><h2 class="margin-bottom margin-small">PBS-15</h2><div class="product-description"><p class="text-color-blue">Continue your cell culture process scale up for clinical stage production. 15L maximum working volume.</p></div><div class="product-line-button-wrapper"><a href="/products/pbs-15" class="product-info-button w-button">Product info</a><a href="#" class="download-button w-button">Download manual</a></div></div><div class="product-list-right"><img src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/62def55c0252eb144ae4f122_PBS%2015L.png" loading="lazy" alt=""/></div></div></div><div role="listitem" class="w-dyn-item"><div class="product-list"><div id="w-node-_18038298-799e-fac3-6c8e-4248fe7e01fd-3517ba48" class="product-list-left"><h2 class="margin-bottom margin-small">PBS-80</h2><div class="product-description"><p class="text-color-blue">Prepare for commercial-scale manufacturing of your cell therapy products. 80L maximum working volume.</p></div><div class="product-line-button-wrapper"><a href="/products/pbs-80" class="product-info-button w-button">Product info</a><a href="#" class="download-button w-button">Download manual</a></div></div><div class="product-list-right"><img src="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/62def5213b03ce1dee2d37ae_PBS%2080L.png" loading="lazy" 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