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page-content main-wrapper"> <div class="shadow-right">  <div id="main"> <div id="main-inside" class="clear-block">  <div id="primary-content"> <div class="blocks"> <h1 class="title">Bruce Nash</h1> <div class="clear-block"> <div class="alignleft"><img alt='' src='http://0.gravatar.com/avatar/0d009ffcd9b739094e10c60d3e6c9166?s=128&d=http%3A%2F%2F0.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D128&r=G' class='avatar avatar-128 photo' height='128' width='128' /></div> <div> <p> This user hasn't shared any biographical information </p> <p class="im www">Homepage: <a href="http://dnalc.org/about/staff/nash.html">http://dnalc.org/about/staff/nash.html</a></p> </div> </div> <div class="divider"></div> <br /> <h3 class="title">Posts by Bruce Nash</h3> <div class="divider"></div>  <div id="post-4845" class="hentry post post-1 odd author-nash category-insidecancer post_tag-cancer post_tag-dna post_tag-dna-learning-center post_tag-dnaftb post_tag-evolution post_tag-inside-cancer post_tag-mutation post_tag-transposon clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2012/08/28/jumping-down-the-road-to-cancer/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2012/08/mobiledna-100x100.jpg" class="attachment-post-thumbnail" alt="DNA contains Jumping Genes" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2012/08/28/jumping-down-the-road-to-cancer/" rel="bookmark" title="Permanent Link: Jumping Down the Road to Cancer.">Jumping Down the Road to Cancer.</a></h2> <div class="post-date"> <p class="day">Aug 28th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2012/08/28/jumping-down-the-road-to-cancer/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p>Lying dormant in our genomes are millions of <a title="Some DNA can jump." href="http://www.dnaftb.org/32/">jumping genes</a>. Originally discovered by Barbara McClintock, <a title="Transposons" href="http://www.dnaftb.org/32/">transposons </a>are DNA sequences that can move from one location to another in our DNA. Transposons cause mutations when they jump to new locations, so keeping them from jumping is important. However, although <a title="Transposons" href="http://www.dnaftb.org/32/">transposons</a> are largely silent, every person probably has a few “rare” sites, found in only a few people in the world, where a transposon has jumped to a new location.</p> <a href="http://blogs.dnalc.org/wp-content/uploads/2012/08/mobiledna.jpg"></a> <p> </p> <p><a href="http://www.dnaftb.org/27/">Mutations </a>in numerous pathways need to accumulate for cancer to progress. Given the ability of <a title="Transposons" href="http://www.dnaftb.org/32/">transposons</a> to cause mutation and <a title="Hallmarks of Cancer, Promoting Mutations" href="http://teachercenter.insidecancer.org/view/Hallmarks%20of%20Cancer/951/Hallmarks,%20Promoting%20mutations.html">the role of mutation in </a><a class="more-link" href="http://blogs.dnalc.org/2012/08/28/jumping-down-the-road-to-cancer/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/cancer/" rel="tag" title="Cancer (25 topics)">Cancer</a>, <a href="http://blogs.dnalc.org/tag/dna/" rel="tag" title="dna (36 topics)">dna</a>, <a href="http://blogs.dnalc.org/tag/dna-learning-center/" rel="tag" title="DNA Learning Center (1 topics)">DNA Learning Center</a>, <a href="http://blogs.dnalc.org/tag/dnaftb/" rel="tag" title="dnaftb (1 topics)">dnaftb</a>, <a href="http://blogs.dnalc.org/tag/evolution/" rel="tag" title="Evolution (9 topics)">Evolution</a>, <a href="http://blogs.dnalc.org/tag/inside-cancer/" rel="tag" title="Inside Cancer (2 topics)">Inside Cancer</a>, <a href="http://blogs.dnalc.org/tag/mutation/" rel="tag" title="mutation (5 topics)">mutation</a>, <a href="http://blogs.dnalc.org/tag/transposon/" rel="tag" title="transposon (2 topics)">transposon</a> </div> </div>   <div id="post-4664" class="hentry post post-2 even alt author-nash category-insidecancer clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2012/04/04/find-cancer-can-you-hear-the-light/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2012/04/Melanoma3DMovie-100x100.gif" class="attachment-post-thumbnail" alt="Melanoma3DMovie" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2012/04/04/find-cancer-can-you-hear-the-light/" rel="bookmark" title="Permanent Link: Finding Cancer: Can you hear the light?">Finding Cancer: Can you hear the light?</a></h2> <div class="post-date"> <p class="day">Apr 4th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2012/04/04/find-cancer-can-you-hear-the-light/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p style="text-align: left">Finding cancers early allows for more effective treatment with the least side effects, so finding better ways to detect cancers is an important part of the fight. A new technique may help us “hear” where cancers are, allowing doctors to diagnose cancers more precisely than is currently possible. The technique, which is called photoacoustic tomography, takes pictures of sound waves that come from tissues when laser light is shined on the tissue. This is possible because different parts of the body absorb different amounts of light. When light is absorbed, it raises the temperature of the tissue, and the temperature <a class="more-link" href="http://blogs.dnalc.org/2012/04/04/find-cancer-can-you-hear-the-light/">More ></a></p> </div> </div>   <div id="post-4600" class="hentry post post-3 odd author-nash category-insidecancer post_tag-cancer post_tag-diesel post_tag-epidemiology post_tag-lungs post_tag-pollution post_tag-risk clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2012/03/07/exhausting-our-lungs/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2012/03/yellowbus-100x100.jpg" class="attachment-post-thumbnail" alt="yellowbus" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2012/03/07/exhausting-our-lungs/" rel="bookmark" title="Permanent Link: Exhausting Our Lungs">Exhausting Our Lungs</a></h2> <div class="post-date"> <p class="day">Mar 7th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2012/03/07/exhausting-our-lungs/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p> </p> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2012/03/yellowbus.jpg"></a></p> <p>I have often wondered what impact the diesel fumes from yellow school buses might have on students. I know that I don’t like driving behind those buses because the fumes don’t smell good, so it seemed to me that there might be some health consequences. Others have wondered, too, and there is evidence that exhaust levels in buses can have health effects. However, it is hard to study this sort of thing, because finding people that are exposed to high levels of diesel in a controlled environment over long enough periods to measure the effects is challenging. Now, a study <a class="more-link" href="http://blogs.dnalc.org/2012/03/07/exhausting-our-lungs/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/cancer/" rel="tag" title="Cancer (25 topics)">Cancer</a>, <a href="http://blogs.dnalc.org/tag/diesel/" rel="tag" title="diesel (1 topics)">diesel</a>, <a href="http://blogs.dnalc.org/tag/epidemiology/" rel="tag" title="epidemiology (1 topics)">epidemiology</a>, <a href="http://blogs.dnalc.org/tag/lungs/" rel="tag" title="lungs (1 topics)">lungs</a>, <a href="http://blogs.dnalc.org/tag/pollution/" rel="tag" title="pollution (1 topics)">pollution</a>, <a href="http://blogs.dnalc.org/tag/risk/" rel="tag" title="risk (2 topics)">risk</a> </div> </div>   <div id="post-4513" class="hentry post post-4 even alt author-nash category-insidecancer post_tag-angiogenesis post_tag-biology post_tag-blood-vessels post_tag-breast post_tag-cancer post_tag-drugs clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/"><img width="72" height="72" src="http://blogs.dnalc.org/wp-content/uploads/2012/02/angio.jpg" class="attachment-post-thumbnail" alt="angio" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/" rel="bookmark" title="Permanent Link: Tumor Treatment: Whether to Shrink or Not to Shrink">Tumor Treatment: Whether to Shrink or Not to Shrink</a></h2> <div class="post-date"> <p class="day">Feb 6th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p>Just like normal tissue, tumors need blood vessels to grow. Because of this, drugs that stop angiogenesis, or the formation of new blood vessels, are one important approach to treating cancers. These angiogenesis inhibitors stop tumor growth by starving them of oxygen and nutrients, usually by interfering with signals from the tumor cells that promote blood vessel formation in the surrounding tissue. Angiog<a href="http://blogs.dnalc.org/wp-content/uploads/2012/02/angio.jpg"></a>enesis inhibitors have been shown to be effective in the treatment of several cancer types, but the results aren’t always as expected. Several recent studies show how complicated this can be. For instance, FDA approval of the drug <a class="more-link" href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/angiogenesis/" rel="tag" title="angiogenesis (1 topics)">angiogenesis</a>, <a href="http://blogs.dnalc.org/tag/biology/" rel="tag" title="biology (4 topics)">biology</a>, <a href="http://blogs.dnalc.org/tag/blood-vessels/" rel="tag" title="blood vessels (1 topics)">blood vessels</a>, <a href="http://blogs.dnalc.org/tag/breast/" rel="tag" title="breast (1 topics)">breast</a>, <a href="http://blogs.dnalc.org/tag/cancer/" rel="tag" title="Cancer (25 topics)">Cancer</a>, <a href="http://blogs.dnalc.org/tag/drugs/" rel="tag" title="drugs (4 topics)">drugs</a> </div> </div>   <div id="post-4327" class="hentry post post-5 odd author-nash category-insidecancer clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2011/12/13/cancer-overtreatment-when-the-solution-is-worse-than-the-problem/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2011/12/doc-100x100.jpg" class="attachment-post-thumbnail" alt="Doctor and Patient" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2011/12/13/cancer-overtreatment-when-the-solution-is-worse-than-the-problem/" rel="bookmark" title="Permanent Link: Cancer Overtreatment. When the solution is worse than the problem.">Cancer Overtreatment. When the solution is worse than the problem.</a></h2> <div class="post-date"> <p class="day">Dec 13th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2011/12/13/cancer-overtreatment-when-the-solution-is-worse-than-the-problem/#comments" class=" comments">1 comment</a></p> </div> <div class="post-content clear-block"> <p>We often focus on cancers that are lethal, and especially those that can’t be treated, and for obvious reasons. This week, the National Institutes of Health addressed a different concern- that sometimes a cancer that isn’t life threatening is best left alone. In this case, it is prostate cancer, which affects about 30 to 40 percent of men over 50. About 240,000 men are diagnosed with prostate cancer a year, and over 30,000 die of the disease – so it is far from being rare or harmless for many. However, over half of prostate cancers are localized and many will <a class="more-link" href="http://blogs.dnalc.org/2011/12/13/cancer-overtreatment-when-the-solution-is-worse-than-the-problem/">More ></a></p> </div> </div>   <div id="post-4251" class="hentry post post-6 even alt author-nash category-insidecancer clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2011/11/08/designer-biology-in-the-fight-against-cancer/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2011/11/HeLa-Sensor-100x100.gif" class="attachment-post-thumbnail wp-post-image" alt="Adapted from Xie, et al." /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2011/11/08/designer-biology-in-the-fight-against-cancer/" rel="bookmark" title="Permanent Link: Designer Biology in the Fight against Cancer">Designer Biology in the Fight against Cancer</a></h2> <div class="post-date"> <p class="day">Nov 8th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2011/11/08/designer-biology-in-the-fight-against-cancer/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2011/11/hela-sensor.tif"></a>As many of you know and I have discussed before, cancer therapies have to target cancer cells while minimizing damage to normal cells. This is very difficult, in part because cancer cells are, although altered, still human cells. Synthetic biology is a new field that engineers biological systems for different applications. One interesting area where synthetic biology is now being applied is to cancer therapies. One advantage is that it may be possible to engineer sensors that can differentiate normal cells from tumor cells.</p> <p>Early approaches have used engineering to create bacteria that specifically invade tumor cells. In one approach, bacteria <a class="more-link" href="http://blogs.dnalc.org/2011/11/08/designer-biology-in-the-fight-against-cancer/">More ></a></p> </div> </div>   <div id="post-4111" class="hentry post post-7 odd author-nash category-insidecancer clear-block"> <h2 class="title"><a href="http://blogs.dnalc.org/2011/10/03/a-prize-and-a-passing/" rel="bookmark" title="Permanent Link: A Prize and a Passing">A Prize and a Passing</a></h2> <div class="post-date"> <p class="day">Oct 3rd</p> </div> <div class="post-info clear-block "> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2011/10/03/a-prize-and-a-passing/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p>As some of you may have noticed, I have blogged about pancreatic cancer in the past because it is such a nasty type of cancer. Now, pancreatic cancer is in the news because, sadly, Ralph M. Steinman, who was awarded the Nobel Prize in Physiology or Medicine for his ground-breaking work on the immune system, died before he could receive the Award. Dr. Steinman primarily worked on immune cells, but his work also touched on cancer. The immune system monitors the body for both foreign invaders, like bacterial infections, and rogue cells that might become cancerous. The immune system is <a class="more-link" href="http://blogs.dnalc.org/2011/10/03/a-prize-and-a-passing/">More ></a></p> </div> </div>   <div id="post-1592" class="hentry post post-8 even alt author-nash category-insidecancer post_tag-cancer-diet-oncogene-mutation-dna clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2011/05/12/feed-a-cold-and-starve-a-cancer/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2010/08/4024368125_6cee3d572d-100x100.jpg" class="attachment-post-thumbnail wp-post-image" alt="B0006421 Breast cancer cells" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2011/05/12/feed-a-cold-and-starve-a-cancer/" rel="bookmark" title="Permanent Link: Feed a cold and starve a cancer?">Feed a cold and starve a cancer?</a></h2> <div class="post-date"> <p class="day">May 12th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2011/05/12/feed-a-cold-and-starve-a-cancer/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2010/08/4024368125_6cee3d572d.jpg"></a>A recent review in Oncogene discusses how fasting may help patients who have been diagnosed with cancer. This is interesting, because at the moment most people are advised to eat extra calories and proteins while undergoing cancer treatments. It turns out that in animals fasting changes the physiology of the body and this can help protect normal cells from the damaging effects of anti-cancer agents. The amazing thing is that cancer cells are abnormal and don’t get the same protection, so fasting seems to be a way to help normal cells and not help the targets of the treatment. It <a class="more-link" href="http://blogs.dnalc.org/2011/05/12/feed-a-cold-and-starve-a-cancer/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/cancer-diet-oncogene-mutation-dna/" rel="tag" title="cancer diet oncogene mutation dna (1 topics)">cancer diet oncogene mutation dna</a> </div> </div>   <div id="post-1578" class="hentry post post-9 odd author-nash category-insidecancer post_tag-cancer post_tag-diagnosis post_tag-disease post_tag-dna post_tag-genomics post_tag-mutations post_tag-sequencing post_tag-treatment clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2011/02/18/cancer-genomics-so-many-mutations/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2011/02/network-300x198-100x100.gif" class="attachment-post-thumbnail wp-post-image" alt="network-300x198" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2011/02/18/cancer-genomics-so-many-mutations/" rel="bookmark" title="Permanent Link: Cancer Genomics: so many mutations!">Cancer Genomics: so many mutations!</a></h2> <div class="post-date"> <p class="day">Feb 18th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2011/02/18/cancer-genomics-so-many-mutations/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2011/02/network-300x198.gif"></a>The human genome is the complete collection of over three billion bases in each of our cells. Cancers accumulate multiple changes, or mutations, in their DNA that contribute to the disease by changing how cells behave. For instance, cancers need nutrients to grow. Very often, they get these nutrients by producing signals that encourage new blood vessel formation. Finding the mutations that lead to cancer is very difficult. For one thing, even for cancers that affect the same tissue and look similar, the mutations can be very different. Also, one of the hallmarks of cancer is an increased rate of <a class="more-link" href="http://blogs.dnalc.org/2011/02/18/cancer-genomics-so-many-mutations/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/cancer/" rel="tag" title="Cancer (25 topics)">Cancer</a>, <a href="http://blogs.dnalc.org/tag/diagnosis/" rel="tag" title="diagnosis (3 topics)">diagnosis</a>, <a href="http://blogs.dnalc.org/tag/disease/" rel="tag" title="disease (13 topics)">disease</a>, <a href="http://blogs.dnalc.org/tag/dna/" rel="tag" title="dna (36 topics)">dna</a>, <a href="http://blogs.dnalc.org/tag/genomics/" rel="tag" title="genomics (5 topics)">genomics</a>, <a href="http://blogs.dnalc.org/tag/mutations/" rel="tag" title="mutations (5 topics)">mutations</a>, <a href="http://blogs.dnalc.org/tag/sequencing/" rel="tag" title="Sequencing (4 topics)">Sequencing</a>, <a href="http://blogs.dnalc.org/tag/treatment/" rel="tag" title="treatment (10 topics)">treatment</a> </div> </div>   <div id="post-1410" class="hentry post post-10 even alt author-nash category-insidecancer post_tag-addiction post_tag-cancer post_tag-dna post_tag-epigenetic post_tag-genes post_tag-mutations clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2010/06/09/addicted-cancers/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2010/06/cancer-cell-smoking1-100x100.gif" class="attachment-post-thumbnail wp-post-image" alt="cancer-cell-smoking1" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2010/06/09/addicted-cancers/" rel="bookmark" title="Permanent Link: Addicted cancers">Addicted cancers</a></h2> <div class="post-date"> <p class="day">Jun 9th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2010/06/09/addicted-cancers/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2010/06/cancer-cell-smoking1.gif"></a>Most people know that smoking is a hard habit to kick because smokers become addicted to the nicotine and habit. Equally sad is the tendency of young adolescents to start smoking for social and psychological reasons.</p> <p>In a turn-around of sorts, it may be comforting to know that cancers can become addicted, too. Cancer cells have many different genetic changes, as well as changes in the expression of genes that are not due to mutations called epigenetic changes. Although cancer cells do have many differences from normal cells, they are still very similar to normal cells, making it very difficult to <a class="more-link" href="http://blogs.dnalc.org/2010/06/09/addicted-cancers/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/addiction/" rel="tag" title="addiction (3 topics)">addiction</a>, <a href="http://blogs.dnalc.org/tag/cancer/" rel="tag" title="Cancer (25 topics)">Cancer</a>, <a href="http://blogs.dnalc.org/tag/dna/" rel="tag" title="dna (36 topics)">dna</a>, <a href="http://blogs.dnalc.org/tag/epigenetic/" rel="tag" title="epigenetic (2 topics)">epigenetic</a>, <a href="http://blogs.dnalc.org/tag/genes/" rel="tag" title="genes (11 topics)">genes</a>, <a href="http://blogs.dnalc.org/tag/mutations/" rel="tag" title="mutations (5 topics)">mutations</a> </div> </div>   <div class="page-navigation clear-block"> <span class="current">1</span><a href="http://blogs.dnalc.org/author/nash/page/2/" title="Go to 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2009 <span class="details inline">(16)</span></span></a></li> <li><a href='http://blogs.dnalc.org/2009/09/' class="fadeThis"><span class="entry">September 2009 <span class="details inline">(12)</span></span></a></li> <li><a href='http://blogs.dnalc.org/2009/08/' class="fadeThis"><span class="entry">August 2009 <span class="details inline">(3)</span></span></a></li> <li><a href='http://blogs.dnalc.org/2009/07/' class="fadeThis"><span class="entry">July 2009 <span class="details inline">(2)</span></span></a></li> <li><a href='http://blogs.dnalc.org/2009/05/' class="fadeThis"><span class="entry">May 2009 <span class="details inline">(2)</span></span></a></li> <li><a href='http://blogs.dnalc.org/2009/04/' class="fadeThis"><span class="entry">April 2009 <span class="details inline">(2)</span></span></a></li> </ul> </div> </div> </div> <div class="box section" id="sidebartabswidget-3-section-popular"> <div class="box-top-left"><div class="box-top-right"></div></div> <div class="box-main"> 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href="http://blogs.dnalc.org/2010/04/29/dna-day-2010-what-me-worry-about-my-dna/#comment-8491"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/d378d3a40a3590dd63b538282ae6b78a?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Mohammed Khalfan: <span class="details"> Hi Traci, you should check this website out http://www.23andme.com/ - just might be what you're...</span></span></a></li> <li class="clear-block"><a title="Posted in: IQ Tests as a Measure of Intelligence" class="fadeThis" href="http://blogs.dnalc.org/2011/09/28/iq-tests-as-a-measure-of-intelligence/#comment-5440"><span class="avatar"><img alt='' src='http://0.gravatar.com/avatar/6b23915f2fdd2da3dc5c657112de54a5?s=32&d=http%3A%2F%2F0.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Sue: <span class="details"> I agree. IQ tests are overated. They are based on assumptions about the nature of intelligence,...</span></span></a></li> <li class="clear-block"><a title="Posted in: Cancer Overtreatment. When the solution is worse than the problem." class="fadeThis" href="http://blogs.dnalc.org/2011/12/13/cancer-overtreatment-when-the-solution-is-worse-than-the-problem/#comment-5439"><span class="avatar"><img alt='' src='http://0.gravatar.com/avatar/ad516503a11cd5ca435acc9bb6523536?s=32' class='avatar avatar-32 photo avatar-default' height='32' width='32' /></span><span class="entry">points of view: <span class="details"> On My Twitter Feed... Then I checked my personal feed and saw somebody posting the link to the...</span></span></a></li> <li class="clear-block"><a title="Posted in: Tag…You’re It!" class="fadeThis" href="http://blogs.dnalc.org/2012/01/19/tag-youre-it/#comment-5359"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/52935aba909ed59a5789008268b14fdb?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">talha: <span class="details"> the wonders of science i wanna be performing this epigenetic tag therapy.</span></span></a></li> <li class="clear-block"><a title="Posted in: Merry Christmas to Hemophilia Patients" class="fadeThis" href="http://blogs.dnalc.org/2011/12/15/merry-christmas-to-hemophilia-patients/#comment-5358"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/52935aba909ed59a5789008268b14fdb?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">talha: <span class="details"> this is just a tip of an iceberg whats gonna happen more and more can only be expected from gene...</span></span></a></li> <li class="clear-block"><a title="Posted in: DNA DAY 2010: What, me worry about my DNA?" class="fadeThis" href="http://blogs.dnalc.org/2010/04/29/dna-day-2010-what-me-worry-about-my-dna/#comment-4616"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/fe0f32261332c54b99b24c06881c2573?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Traci: <span class="details"> How would I go about getting my DNA tested? Being an adopted child, we have exhausted legal alleys...</span></span></a></li> <li class="clear-block"><a title="Posted in: AIDS Cure UPDATE" class="fadeThis" href="http://blogs.dnalc.org/2011/10/15/aids-cure-update/#comment-1607"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/997a441b2802e625590c2adc4ea2545f?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Heaven: <span class="details"> This is really amazing. This is just another step to curing some of the most devastating diseases...</span></span></a></li> <li class="clear-block"><a title="Posted in: Compulsive Hoarding" class="fadeThis" href="http://blogs.dnalc.org/2011/11/10/compulsive-hoarding/#comment-1245"><span class="avatar"><img alt='' src='http://0.gravatar.com/avatar/cf95176c58575d503b402764e9710135?s=32&d=http%3A%2F%2F0.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Eileen @ Space Matters: <span class="details"> You've got some very interesting info here! Here's some places to go to get do some more...</span></span></a></li> </ul> </div> </div> </div> </div> </div>  </div></li><li class="block"><div class="block-twitter clear-block" id="instance-twitterwidget-3"><h3 class="title"><span>DNALC Twitter Feed</span></h3><div class="block-div"></div><div class="block-div-arrow"></div> <div class="twitter-content clear-block" id="twitterwidget-3"> <script type="text/javascript"> /* <![CDATA[ */ // init jQuery(document).ready(function(){ jQuery.ajax({ // load tweets trough ajax to avoid waiting for twitter's response type: "GET",url: "http://blogs.dnalc.org",data: { widget_id: '3', twituser: 'dnalc', twitcount: '4', get_twitter_data: 1 }, beforeSend: function() {jQuery("#twitterwidget-3 .loading").show("slow");}, complete: function() { jQuery("#twitterwidget-3 .loading").hide("fast");}, success: function(html){ jQuery("#twitterwidget-3").html(html); jQuery("#twitterwidget-3").show("slow"); } }); }); /* ]]> */ </script> <div class="loading">Loading tweets...</div> </div> <a class="followMe" href="http://www.twitter.com/dnalc"><span>Follow me on Twitter!</span></a> </div></li><li class="block"><div class="block-jetpack_subscription_widget clear-block" id="instance-blog_subscription-3"><h3 class="title"><span><label for="subscribe-field">Subscribe to Blog via Email</label></span></h3><div class="block-div"></div><div class="block-div-arrow"></div> <a name="subscribe-blog"></a> <form action="" method="post" accept-charset="utf-8" id="subscribe-blog"> <p>Enter your email address to subscribe to this blog and receive notifications of new posts by email.</p> <p><input type="text" name="email" style="width: 95%; padding: 1px 2px" value="Email Address" id="subscribe-field" onclick="if ( this.value == 'Email Address' ) { this.value = ''; }" onblur="if ( this.value == '' ) { this.value = 'Email Address'; }" /></p> <p> <input type="hidden" name="action" value="subscribe" /> <input type="hidden" name="source" value="http://blogs.dnalc.org/author/nash/" /> <input type="hidden" name="sub-type" value="widget" /> <input type="hidden" name="redirect_fragment" value="blog_subscription-3" /> <input type="hidden" id="_wpnonce" name="_wpnonce" value="9f0697e03d" /> <input type="submit" value="Subscribe" name="jetpack_subscriptions_widget" /> </p> </form> </div></li><li class="block"><div class="block-widget_meta clear-block" id="instance-meta-3"><h3 class="title"><span>Meta</span></h3><div class="block-div"></div><div class="block-div-arrow"></div> <ul> <li><a href="http://blogs.dnalc.org/wp-login.php">Log in</a></li> <li><a href="http://blogs.dnalc.org/feed/" title="Syndicate this site using RSS 2.0">Entries <abbr title="Really Simple Syndication">RSS</abbr></a></li> <li><a href="http://blogs.dnalc.org/comments/feed/" title="The latest comments to all posts in RSS">Comments <abbr title="Really Simple Syndication">RSS</abbr></a></li> <li><a href="http://wordpress.org/" title="Powered by WordPress, state-of-the-art semantic personal publishing platform.">WordPress.org</a></li> </ul> </div></li> </ul> </div> </div> </div>   <div id="footer"> <div class="page-content"> <div id="copyright"> © 2011, <a href="http://www.dnalc.org">DNA Learning Center</a>, <a href="http://www.cshl.edu">Cold Spring Harbor Laboratory</a>. 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