Luminex Assays, Multiplex Immunoassays

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paragraph--type--hero-banner paragraph--view-mode--full paragraph-background-color--dark"> <div class="banner_background_image no-lazy-load" style="background: linear-gradient(to top, rgba(0, 0, 0, 0.0) 0%, rgba(0, 0, 0, 0.90) 100%), url('https://resources.bio-techne.com/bio-techne-assets/images/research-areas/bt-luminexassay-gradient-hero-banner-1500x340.jpg'); background-position: top center; background-repeat: no-repeat; background-size: cover;"> <div> <div class="paragraph paragraph--type--h1-2-2-text-to-media paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:h1_2_2_text_to_media:field_indv_h1"> <div><h1>Luminex<sup>®</sup> Assays</h1></div> </div> <div class="field_block:paragraph:h1_2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Discover and validate biomarker candidates with Luminex Discovery and Luminex High Performance multiplex immunoassays. Profile multiple analytes in one sample.</p></div> </div> <div class="field_block:paragraph:h1_2_2_text_to_media:field_call_to_action_global"> <a href="/p/instruments/luminex-instrumentation/request-quote?productName=Luminex%20200%20RUO%20System%20w/xPONENT%204.3&catalogNumber=LX200-XPON-RUO" class="btn btn-primary" type="link"> Request Pricing </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:h1_2_2_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/bt-luminexassay-gradient-hero-cell-v3.png" alt="Luminex Assay Gradient Hero Cell" fetchpriority="high" > </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> </div> </header> </div> <div id="main" class="container-fluid container-wide"> <div class="row"> <div class="col-md-12"> <div> <div id="block-bio-techne-global-breadcrumbs" class="system_breadcrumb_block"> <nav role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/reagents">Bio-Techne Reagents</a> </li> <li> Luminex Assays </li> </ol> </nav> </div> </div> </div> </div> <main> <section class="section"> <div> <div id="block-bio-techne-global-content" class="system_main_block"> <article> <div> <div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a href="#customization">Assay Customization Tool</a> | <a href="#featured">Featured Products & Content</a> | <a href="#portfolio">Assay Portfolio</a> | <a href="#instruments">Luminex Instruments</a> | <a href="#applications">Applications</a> | <a href="#resources">Resources</a> | <a href="#background">Background Information</a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="customization"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default"> <div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/luminex-lab-scene-2.png" alt="Scientist works in the lab with Luminex xMap instrument" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h3>Multiplex Up to 50 Analytes With Luminex Assays</h3></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Your process can be cost-effective!  Save money, time, and sample volume with a Luminex multiplex assays. Explore the most customizable Luminex analyte menu available, choose from over 450 analytes. Your data will be robust, reliable, and reproducible because every panel is QC tested. Fast delivery times and offering three flexible formats:</p> <ul> <li>Discovery Assays – Completely customizable</li> <li>Fixed High Performance Panels – Fully stocked and ready to ship</li> <li>Configurable High Performance Panels – Select any or all analytes from designed panels</li> </ul></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_call_to_action_global"> <a href="/luminex-assay-customization-tool" class="btn btn-primary" type="link"> Build Your Assay: Luminex Assay Customization Tool </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="featured"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Featured Content</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/p/luminex-assays/mouse-xl-cytokine-luminex-performance-premixed-kit_fcstm20" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/teaser-card-mousexl350x220b.png" alt="Luminex Mouse Cytokine Panel" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/p/luminex-assays/mouse-xl-cytokine-luminex-performance-premixed-kit_fcstm20" > <h3 class="card_title_htag"> <div><h3>Mouse XL Cytokine Assay Performance Panel</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>The largest customizable mouse Luminex assay- providing you with 45 biomarkers and available with 7 exclusive targets (EGF, FGF-basic, Flt-3 Ligand, GDF-15, IL-1ra, IL-11, and LDL R). </p> <p>The panel is provided in multiple format options including premix, user mix, and fixed.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/p/luminex-assays/mouse-xl-cytokine-luminex-performance-premixed-kit_fcstm20" > Get the Luminex Mouse Cytokine Panel Today </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/luminex-assays/early-cancer-detection" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/applications/dividing-cancer-cell-hero1.png" alt="3d rendering of cancer cells splitting" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/reagents/luminex-assays/early-cancer-detection" > <h3 class="card_title_htag"> <div><h3>Overcoming the Hurdles to Early Cancer Detection</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Learn how Bio-Techne and Luminex are working together to develop better tools for early cancer detection and reduce the total cost of care.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/luminex-assays/early-cancer-detection" > Learn More About Early Cancer Detection with Luminex </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/p/luminex-assays/human-tumor-biomarker-luminex-performance-assay_fcstm25" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/human-tumor-biomarker-performance-teaser-300x300.png" alt="Human Tumor Biomarker" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/p/luminex-assays/human-tumor-biomarker-luminex-performance-assay_fcstm25" > <h3 class="card_title_htag"> <div><h3>New Human Tumor Biomarker Performance Panel</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Featuring 28 key biomarkers for precise cancer research including CA125, PSA Total, and neuro-specific enolase. Mix and match customization allows maximum flexibility while providing sensitivity results for early cancer detection.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/p/luminex-assays/human-tumor-biomarker-luminex-performance-assay_fcstm25" > Learn More & Build Your Human Tumor Biomarker Panel </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="thin-banner banner_wrapper"> <div class="banner-dark"> <div> <div><h2>Want the latest immunoassay releases?</h2></div> <a href="/applications/immunoassays/new-product-page" > <button type="button" class="btn btn-primary"> Explore All New Products </button> </a> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="portfolio"></a>Product Portfolio</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default"> <div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Luminex Assays by R&D Systems</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/luminex-assays/luminex-discovery-assays" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/icons/luminex-assay-icon-discovery.png" alt="Luminex assay discovery icon" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/reagents/luminex-assays/luminex-discovery-assays" > <h3 class="card_title_htag"> <div><h4>Luminex Discovery Assays</h4></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Expand multiplexing capabilities without sacrificing specificity.</p> <ul> <li>Create your panel of up to 50 analytes with the largest customizable menu on the market</li> <li>Large catalog of <a href="/p/luminex-assays/human-magnetic-luminex-assay_lxsahm">human</a>, <a href="/p/luminex-assays/mouse-magnetic-luminex-assay_lxsamsm">mouse</a>, <a href="/p/luminex-assays/rat-magnetic-luminex-assay_lxsarm">rat</a>, and <a href="/p/luminex-assays/porcine-discovery-luminex-assay_lxsapm">porcine</a> targets</li> <li>Premixed Luminex panels yield timely results</li> <li>Validated and tested for optimum performance</li> </ul></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/luminex-assays/luminex-discovery-assays" > Luminex Discovery Assays </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/luminex-assays/luminex-high-performance-assays" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/icons/luminex-assay-icon-hiperf.png" alt="Luminex assay high performance icon" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/reagents/luminex-assays/luminex-high-performance-assays" > <h3 class="card_title_htag"> <div><h4>Luminex High Performance Assays</h4></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Correlated with the gold standard Quantikine ELISA kits and validated for specificity, precision, stability, linearity, and recovery, R&D Systems High Performance panels ensure consistent and accurate results.</p> <ul> <li>Optimized panels for human and non-human primates</li> <li>Pick and choose analytes</li> <li>Available as premix or user mix</li> <li>Comprehensive menu</li> </ul></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/luminex-assays/luminex-high-performance-assays" > Luminex High Performance Assay Panels </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/luminex-assays/luminex-high-performance-assays" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/icons/luminex-assay-icon-hiperf-fixed.png" alt="High Performance Fixed panel icon" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/reagents/luminex-assays/luminex-high-performance-assays" > <h3 class="card_title_htag"> <div><h4>Luminex High Performance Fixed Panels</h4></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Our stocked and ready to ship panels are stringently tested for accuracy and precision from lot to lot. Panels are arranged with research areas in mind. Check out some of our fixed panels below.</p> <ul> <li><a href="/p/luminex-assays/human-immunotherapy-luminex-performance-assay-25-plex-fixed-panel_lktm010b">Human Immunotherapy 25-plex</a></li> <li><a href="/p/luminex-assays/human-cytokine-luminex-performance-assay-15-plex-fixed-panel_lktm011b">Human Cytokine 15-plex</a></li> <li><a href="/p/luminex-assays/human-xl-cytokine-luminex-performance-assay-46-plex-fixed-panel_lktm014b">Human XL Cytokine 46-plex</a></li> <li><a href="/p/luminex-assays/human-xl-cytokine-luminex-performance-assay-46-plex-fixed-panel_lktm014b">Mouse XL Cytokine 46-plex</a></li> </ul></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/luminex-assays/luminex-high-performance-assays" > Luminex High Performance Fixed Panels </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="instruments"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Luminex Instruments, Software & Offerings</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/luminex-instruments-trio-2.png" alt="FlexMap 3D, LUminex 200, xMap Intelliflex" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Explore and find the perfect <a href="/instruments/luminex">Luminex instrument</a> for your lab, plus the accessories you need to run your Luminex Multiplex Assays.</p> <ul> <li><a href="/p/luminex-instrument/luminex-intelliflex-single-reporter_intelliflex-ruo">xMAP INTELLIFLEX<sup>®</sup> RUO</a></li> <li><a href="/p/luminex-instrument/luminex-intelliflex-dr-se-dual-reporter_intelliflex-drse-ruo">xMAP INTELLIFLEX<sup>®</sup> DR-SE RUO</a></li> <li><a href="/p/luminex-instrument/luminex-200-ruo-system-w-xponent-4-3_lx200-xpon-ruo">Luminex<sup>®</sup> 100™</a></li> <li><a href="/p/luminex-instrument/luminex-flexmap-3d-w-xponent-4-3_flexmap-3d-ruo">FLEXMAP 3D<sup>®</sup></a><br>  </li> <li><a href="/search?keywords=INTELLIFLEX">xMAP INTELLIFLEX<sup>®</sup> Reagents</a></li> <li><a href="/search?keywords=Luminex%20200">Luminex<sup>®</sup> 200™ Reagents</a></li> <li><a href="/search?keywords=Flexmap%203D">FLEXMAP 3D<sup>®</sup> Reagents</a></li> <li><a href="/search?keywords=Magpix">MAGPIX<sup>®</sup> Reagents</a></li> </ul></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/quantist-display-monitor-1.png" alt="Desktop monitor showing Quantist splash screen" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h3>Quantist Luminex Data Analysis Software</h3></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Bio-Techne's Quantist Luminex data analysis software helps you extract insight from complexity. <a href="/reagents/luminex/luminex-software-quantist">Use this software</a> to evaluate the quality of your standards, controls, and unknowns. Evaluate the long-term consistency of your Luminex data by using Quantist to make inter-assay comparisons. Try before you buy. Free 30-day evaluation licenses are available.</p></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/icons/data-process-light-icon.png" alt="Data Processing Icon" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h3>Custom Luminex Services</h3></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Save development time, conserve your budget, and improve your multiplexing capabilities by utilizing our decades of experience and comprehensive collection of proteins and antibodies to design a panel tailored to your research needs. Bio-Techne will handle your:</p> <ul> <li>Bead region conflict resolution</li> <li>Bulk packaging</li> <li>Lot sequestration</li> <li>New analyte development</li> </ul> <p> <a href="/services/custom-luminex-services">Start a conversation </a>today to learn how Bio-Techne's custom Luminex services can accelerate your research.</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="applications"></a>Applications</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--_-1-text-to-media mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--75-25"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:3_1_text_to_media:field_header_2_global"> <div><h3>Browse Cytokine Products by Family</h3></div> </div> <div class="field_block:paragraph:3_1_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>If you’re looking for more information about products for specific cytokines, cytokine receptors, or signaling molecules, <a href="/reagents/proteins/cytokines">explore the Cytokine Family pages</a> on our website. These pages contain detailed information about cytokines by family, product listings by molecule, data examples, and featured resources to help you find the products that you need to advance your research.</p></div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:3_1_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/common-cytokine-receptor-gamma-chain-guide-teaser-solo.png" alt="Select immune cell types whose development and activities are regulated by common cytokine receptor gamma chain cytokines " loading="lazy" > </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/applications/immunoassays/immune-profiling" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #00263A; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/banners/Animal-Free-Landing-Graphics_teaser7.png" alt="Immune Cell Therapy Teaser" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/applications/immunoassays/immune-profiling" > <h3 class="card_title_htag"> <div><h3>Immune Response Profiling</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Luminex assays are an excellent tool for immune response profiling. Select from over 450 target analytes and profile up to 50 targets in each sample.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/applications/immunoassays/immune-profiling" > Profile the Immune Response </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/applications/immuno-oncology-immunoassays" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #00263A; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/banners/Animal-Free-Landing-Graphics_teaser5.png" alt="Stem Cell Research Teaser" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/applications/immuno-oncology-immunoassays" > <h3 class="card_title_htag"> <div><h3>Immunoassays for Immuno-Oncology Research</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Access a broad range of sensitive and accurate immunoassays for immuno-oncology research.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/applications/immuno-oncology-immunoassays" > Explore Immunoassays </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/applications/immunoassays/animal_models" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #00263A; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/unique-animal-models-a.png" alt="Assorted animal silhouettes" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/applications/immunoassays/animal_models" > <h3 class="card_title_htag"> <div><h3>Immunoassays for Unique Model Systems</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Bio-Techne has hundreds of immunoassays spanning 19 different species. We can support you with your unique model organism research.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/applications/immunoassays/animal_models" > Profile Unique Model Systems </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="resources"></a>Luminex Literature and Guides</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="https://info.rndsystems.com/application-note-luminex-fixation.html" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #00263A; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/literature/teaser-appnote-fixation-b.png" alt="Display mockup of Application Note" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="https://info.rndsystems.com/application-note-luminex-fixation.html" > <h3 class="card_title_htag"> <div><h3>Luminex Fixation Application Note</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><ul> <li>Infectious sample collection and spike</li> <li>Chemical fixation at each phase of assay protocol</li> <li>Determine compatibility with verified formaldehyde fixation protocols</li> </ul></div> </div> <div class="card-bottom-link"> <div> <a href="https://info.rndsystems.com/application-note-luminex-fixation.html" > Download the App Note </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/reagents/luminex-assays/luminex-guide" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #00263A; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/literature/teaser-br-lx-assay-guide-b.png" alt="Display mockup of Luminex Assay Guide brochure" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/reagents/luminex-assays/luminex-guide" > <h3 class="card_title_htag"> <div><h3>Luminex Assay Users Guide</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>The Luminex Assays User Guide will help you better understand R&D Systems multiplex offerings and how you can ensure performance and consistency every time.</p> <p>You will learn:</p> <ul> <li>Best practices for sample preparation and data analysis</li> <li>Luminex assay protocol</li> <li>Multiplex techniques, tips, and troubleshooting</li> </ul></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/luminex-assays/luminex-guide" > Download the Brochure </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="https://resources.rndsystems.com/images/site/rnd-systems-iaquality-brochure.pdf" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: #00263A; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/literature/teaser-br-essentials-b.png" alt="Display mockup of brochure" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="https://resources.rndsystems.com/images/site/rnd-systems-iaquality-brochure.pdf" > <h3 class="card_title_htag"> <div><h3>Essentials of Immunoassay Quality Brochure</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Accurate and reliable immunoassay data is indispensable for healthcare.</p> <p>From clinical research and trials to critical quality attributes (CQAs) for bio-therapeutic manufacturing, immunoassays are an indispensable tool to reliably measure protein levels.</p></div> </div> <div class="card-bottom-link"> <div> <a href="https://resources.rndsystems.com/images/site/rnd-systems-iaquality-brochure.pdf" > Access the Brochure </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-1-text-to-media mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--75-25"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:3_1_text_to_media:field_header_2_global"> <div><h3>Immunoassay Solutions for Neuroinflammation</h3></div> </div> <div class="field_block:paragraph:3_1_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Explore Bio-Techne’s immunoassay solutions designed to support every phase, from discovery to validation. Download this brochure to uncover our guide to identifying the ideal product line for your neuroinflammation research with Ella™, ELISA, and Luminex®.</p></div> </div> <div class="field_block:paragraph:3_1_text_to_media:field_call_to_action_global"> <a href="/resources/literature/assays-neuroinflammation-research" class="btn btn-primary" type="link"> Read Now </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:3_1_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/literature/neuroinflammation-br-250x185-thumb1.png" alt="preview of the brochure Assays for Neuroinflammation Research" loading="lazy" > </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <article> <div class="youtube-video-place"> <lite-youtube videoid="nkosWLW0wEs" params="rel=0" style="background-image: url('https://img.youtube.com/vi/nkosWLW0wEs/maxresdefault.jpg');"> <a href="https://www.youtube.com/embed/nkosWLW0wEs?autoplay=1" class="lty-playbtn" title="Identifying False Positives In Immunoassays"> <span class="lyt-visually-hidden">Identifying False Positives In Immunoassays</span> </a> </lite-youtube> </div> </article> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h3>Webinar: Identifying and Removing False Positives in Immunoassays</h3></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Bio-Techne immunoassays accurately quantify biomarkers in complex sample matrices. In this webinar learn how we control for various factors present in the matrices to reduce and eliminate:</p> <ul> <li>False positives</li> <li>False negatives</li> <li>Interference</li> </ul></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <article> <div class="youtube-video-place"> <lite-youtube videoid="tQ27pt_PmhU" params="rel=0" style="background-image: url('https://img.youtube.com/vi/tQ27pt_PmhU/maxresdefault.jpg');"> <a href="https://www.youtube.com/embed/tQ27pt_PmhU?autoplay=1" class="lty-playbtn" title="Luminex Ordering Tool - How To"> <span class="lyt-visually-hidden">Luminex Ordering Tool - How To</span> </a> </lite-youtube> </div> </article> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h3>Learn How to Use the Luminex Assay Customization Tool</h3></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Are you ready to build your assay with the <a href="/luminex-assay-customization-tool">Luminex Assay Customization Tool</a>?  Watch this video to learn how to configure and create your Luminex assay.</p></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <article> <div class="youtube-video-place"> <lite-youtube videoid="eEwaeRXy8jw" params="rel=0" style="background-image: url('https://img.youtube.com/vi/eEwaeRXy8jw/maxresdefault.jpg');"> <a href="https://www.youtube.com/embed/eEwaeRXy8jw?autoplay=1" class="lty-playbtn" title="How to Run a Luminex Standard Curve"> <span class="lyt-visually-hidden">How to Run a Luminex Standard Curve</span> </a> </lite-youtube> </div> </article> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h3>How to Run a Luminex Standard Curve</h3></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Watch this brief video to learn how to generate a standard curve for Luminex assays.</p></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <article> <div class="youtube-video-place"> <lite-youtube videoid="RKbzN0-h1UI" params="rel=0" style="background-image: url('https://img.youtube.com/vi/RKbzN0-h1UI/maxresdefault.jpg');"> <a href="https://www.youtube.com/embed/RKbzN0-h1UI?autoplay=1" class="lty-playbtn" title="How to Run an R&D Systems Luminex® Assay: Protocol, Tips & Tricks"> <span class="lyt-visually-hidden">How to Run an R&D Systems Luminex® Assay: Protocol, Tips & Tricks</span> </a> </lite-youtube> </div> </article> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h3>Learn How to Run a Luminex Assay</h3></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Follow our step-by-step guidance to learn how to maximize your Luminex Performance.</p></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph accordion mb-4 paragraph--type--extendable-paragraph paragraph--view-mode--default"> <div class="card-header rounded-top bg-white"> <a class="collapsed" data-toggle="collapse" href="#expPara-additional-protocols-assay-principles-and-guides21" role="button" aria-expanded="false" aria-controls="expPara"> <h5>Additional Protocols, Assay Principles and Guides</h5> </a> </div> <div class="collapse" id="expPara-additional-protocols-assay-principles-and-guides21" aria-expanded="false" aria-controls="expPara"> <div class="card-body p-4"> <br/> <div><ul> <li><a href="https://www.rndsystems.com/resources/protocols/troubleshooting-guide-luminex" target="_blank">Troubleshooting Guide: Luminex Assays</a></li> <li><a href="https://www.youtube.com/watch?v=xUhUPeLyTEs&t=3s" target="_blank">R&D Systems<sup>®</sup> Immunoassays and Luminex<sup>®</sup> Instruments Video</a></li> <li><a href="https://www.rndsystems.com/resources/protocols/protocol-characterization-human-regulatory-t-cells" target="_blank">Protocol for the Characterization of Human Regulatory T Cells</a></li> <li><a href="https://www.rndsystems.com/resources/protocols/protocol-differentiation-and-characterization-human-th1-cells" target="_blank">Protocol for the Differentiation and Characterization of Human Th1 Cells</a></li> <li><a href="https://www.rndsystems.com/resources/protocols/protocol-differentiation-and-characterization-human-th2-cells" target="_blank">Protocol for the Differentiation and Characterization of Human Th2 Cells</a></li> <li><a href="https://www.rndsystems.com/resources/protocols/protocol-differentiation-and-characterization-human-th17-cells" target="_blank">Protocol for the Differentiation and Characterization of Human Th17 Cells</a></li> <li><a href="https://resources.bio-techne.com/bio-techne-assets/docs/literature/luminex-assays-instruments.pdf" target="_blank">Luminex<sup>®</sup> Assays and Instruments</a></li> <li><a href="https://www.rndsystems.com/what-luminex-assay" target="_blank">What is a Luminex Assay</a></li> </ul></div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="background"></a>Background on Luminex Immunoassays</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--_-1-text-to-media mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--75-25"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:3_1_text_to_media:field_header_2_global"> <div><h3>What is a Luminex Bead-Based Multiplex Immunoassay?</h3></div> </div> <div class="field_block:paragraph:3_1_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Magnetic Luminex beads are internally dyed to give a distinct spectral signature or bead region. These beads are coated with analyte-specific antibodies where each bead region corresponds to a target analyte. Up to 50 different bead regions are mixed and incubated with the sample to capture analytes.  After capture, a cocktail of biotinylated detection antibodies and a streptavidin-phycoerythrin conjugate is used to detect and quantify.</p> <p><a href="https://www.rndsystems.com/what-luminex-assay" target="_blank">Luminex Assays by R&D Systems</a></p> <p><a href="https://www.rndsystems.com/resources/technical/luminex-assay-principle" target="_blank">View Luminex Assay Principle</a></p> <p> </p></div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:3_1_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/articles/dw-multiplex-assays-248x248.jpg" alt="Luminex Multiplex Immunoassays" loading="lazy" > </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph accordion mb-4 paragraph--type--extendable-paragraph paragraph--view-mode--default"> <div class="card-header rounded-top bg-white"> <a class="collapsed" data-toggle="collapse" href="#expPara-uncover-more-immunoassay-tips-and-insights13" role="button" aria-expanded="false" aria-controls="expPara"> <h5>Uncover More Immunoassay Tips and Insights</h5> </a> </div> <div class="collapse" id="expPara-uncover-more-immunoassay-tips-and-insights13" aria-expanded="false" aria-controls="expPara"> <div class="card-body p-4"> <br/> <div><p>Taken together, R&D Systems® Discovery and High Performance (HP) assays comprise the largest selection of Luminex assays on the market. Assays are available for human, mouse and rat samples such as serum, plasma, and cell culture media. Use Discovery assays to profile potential biomarker candidates. Discovery assays allow you to choose from over 450 targets to multiplex up to 50 analytes in each assay.  The Luminex Assay Customization tool allows you to carefully choose compatible targets. It will obviate any error caused by multiplexing with incompatible analytes. Build your assay using analytes of choice or purchase an off-the-shelf preconfigured panel. A wide variety of panels are available including: Cytokine/Chemokine, Immuno-Oncology Checkpoint, T Cell panels, MMP panels, Sepsis panels and more!</p> <p>Once you have narrowed down your candidates, verify biomarker candidates with R&D Systems Luminex HP assays. HP assays are correlated with R&D Systems Quantikine ELISAs,  which are the most accurate, precise and highly cited ELISA on the market.  Luminex HP assays undergo a rigorous validation process that includes validation of linearity of dilution as well as recovery. HP assays use custom diluents that allow for increase sensitivity. Configure your own with the Luminex Assay Customization tool or purchase an off the shelf panel. Preconfigured panels include: cytokine/ chemokine, cardiac panels and others. Analytes in preconfigured HP panels have been optimized to work together.</p> <ul> <li><a href="/applications/immunoassays/important-plate-based-immunoassay-features" target="_self">What is the most important feature of any plate-based immunoassay?</a></li> <li><a href="/applications/immunoassays/which-immunoassay-will-meet-my-research-needs" target="_self">Which immunoassay will best meet my research needs?</a></li> <li><a href="/applications/immunoassays/immunoassay-expert-advice" target="_self">What are some other ways to improve immunoassay performance?</a></li> <li><a href="/methods/immunoassays/multiplex-immunoassays#key-features" target="_self">How do I optimize the performance of my multiplex immunoassay?</a></li> <li><a href="/applications/immunoassays" target="_self">Immunoassay Workflow Solutions</a></li> <li><a href="https://www.rndsystems.com/resources/faqs/luminex-assays" target="_blank">Luminex FAQs</a></li> <li><a href="https://www.rndsystems.com/product-highlights/unique-luminex-analytes" target="_blank">Unique Luminex<sup>®</sup> Analytes</a></li> <li><a href="https://www.rndsystems.com/blog/luminex-hp-assays-101-sensitivity-matters" target="_blank">Luminex HP Assays 101 - Sensitivity Matters</a></li> <li><a href="https://www.rndsystems.com/blog/luminex-high-performance-assays-101-consistency" target="_blank">Luminex High-Performance Assays 101: Consistency</a></li> <li><a href="https://www.rndsystems.com/blog/luminex-hp-assays-101-overcoming-multiplexing-challenges" target="_blank">Luminex<sup>®</sup> HP Assays 101 – Overcoming Multiplexing Challenges</a></li> <li><a href="https://www.rndsystems.com/resources/literature/immunoassay-solutions-neuroinflammation" target="_blank">Immunoassay Solutions for Neuroinflammation</a></li> <li><a href="https://www.rndsystems.com/resources/posters/predicting-cell-line-variability-cardiomyocyte-differentiation-efficiency-using" target="_blank">Predicting 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