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Scale-up and Yield Improvement Services | PBS Biotech
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class="section-services-overview"><div class="page-padding"><div class="conferences-container w-container"><div class="quote-overview-component section-revolutionary"><div class="service-description-wrapper"><h2 class="sub-hero-header">We Can Maximize The Yield and Quality of Your Cells</h2><div class="heading-large text-align-center text-weight-light">PBS Biotech's scientists and chemical engineers have industry-leading expertise in developing cell culture procedures for various types of therapeutic cells. Based on your process requirements, we will design a scalable process for tech transfer. Our customers have achieved key milestones such as scaling up PSC cultures to successfully navigate first-in-human trials. </div></div></div></div></div></section><div class="section-biolab"><div class="page-padding"><div class="conferences-container w-container"><div class="biolab-component"><h2 class="product-resources-header">Process Development Capabilities</h2><h3 class="heading-19">Our BioLab team has extensive experience with scalable cell culture processes involving cell types such as PSCs grown as aggregates, MSCs grown on microcarriers, and CAR-T or NK single cells. Using our 2,940 square feet, state-of the art research laboratory, our team of dedicated scientists can develop and scale up processes optimized for your particular cell lines:</h3><ul role="list" class="biolab-list"><li class="biolab-list2">Seed expansion from a working cell bank and serial passaging</li><li class="biolab-list2">Aggregate-based processes including seeding, expansion, differentiation, dissociation, and harvesting</li><li class="biolab-list2">Microcarrier-based processes including seeding, expansion, detachment, and harvesting</li><li class="biolab-list2">Rapid medium exchange techniques</li><li class="biolab-list2">Cell separation, washing, and concentration</li></ul></div></div></div></div><div class="section-cell"><div class="page-padding"><div class="conferences-container w-container"><h3 class="heading-20">Examples of Customer Challenges</h3><div class="cell-card-wrapper"><div id="w-node-_84d7dab2-fd01-3ffb-b92d-025e35039403-3a484eb3" class="cell-item"><h3 class="main-header">Unfamiliar with the requirements of suspension cultures for human cells</h3></div><div id="w-node-_9d44c029-9589-2b01-db0b-53a9b07abe81-3a484eb3" class="cell-item"><h3 class="main-header">Unsure on how to adapt a small-scale process for clinical or commercial needs</h3></div><div id="w-node-_943b8048-5758-e252-d036-fe59465aa85c-3a484eb3" class="cell-item"><h3 class="main-header">Unsatisfied with yield and/or quality of cells from current process</h3></div></div></div></div></div><div class="section-testimonial"><div class="page-padding"><div class="conferences-container w-container"><div data-delay="4000" data-animation="slide" class="testimonial-slider w-slider" data-autoplay="false" data-easing="ease" data-hide-arrows="false" data-disable-swipe="false" data-autoplay-limit="0" data-nav-spacing="3" data-duration="500" data-infinite="false" id="testimonial"><div class="slider-mask w-slider-mask"><div class="slider-item w-slide"><div class="slider-content-wrapper"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe7309b59484ef8_block-quote.svg" loading="lazy" width="40" alt="" class="quote-image"/><div class="slider-heading">"Our experience with PBS technical support has been above and beyond. They're readily available to provide both support virtually as well as on site. We've built a very great relationship with the team."</div><div class="testimonial-name-wrap"><div class="text-size-regular">Emily Benz</div><div class="text-size-small">Engineer, Process Development - Viacyte Inc.</div></div></div></div><div class="slider-item w-slide"><div class="slider-content-wrapper"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe7309b59484ef8_block-quote.svg" loading="lazy" alt=""/><div class="slider-heading">"Our experience with PBS technical support has been above and beyond. They're readily available to provide both support virtually as well as on site. We've built a very great relationship with the team."</div><div class="testimonial-name-wrap"><div class="text-size-regular">Emily Benz</div><div class="text-size-small">Engineer II, Process Development</div><div class="text-size-small color-grey">Viacyte Inc.</div></div></div><div fs-sliderdots-active="fs-sliderdots_active" fs-sliderdots-element="content" fs-sliderdots-remove="true" class="custom-dots"></div></div><div class="slider-item w-slide"><div class="slider-content-wrapper"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe7309b59484ef8_block-quote.svg" loading="lazy" alt=""/><div class="slider-heading">"Our experience with PBS technical support has been above and beyond. They're readily available to provide both support virtually as well as on site. We've built a very great relationship with the team."</div><div class="testimonial-name-wrap"><div class="text-size-regular">Emily Benz</div><div class="text-size-small">Engineer II, Process Development</div><div class="text-size-small color-grey">Viacyte Inc.</div></div></div><div fs-sliderdots-active="fs-sliderdots_active" fs-sliderdots-element="content" fs-sliderdots-remove="true" class="custom-dots"></div></div><div class="slider-item w-slide"><div class="slider-content-wrapper"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe7309b59484ef8_block-quote.svg" loading="lazy" alt=""/><div class="slider-heading">"Our experience with PBS technical support has been above and beyond. They're readily available to provide both support virtually as well as on site. We've built a very great relationship with the team."</div><div class="testimonial-name-wrap"><div class="text-size-regular">Emily Benz</div><div class="text-size-small">Engineer II, Process Development</div><div class="text-size-small color-grey">Viacyte Inc.</div></div></div><div fs-sliderdots-active="fs-sliderdots_active" fs-sliderdots-element="content" fs-sliderdots-remove="true" class="custom-dots"></div></div><div class="slider-item w-slide"><div class="slider-content-wrapper"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe7309b59484ef8_block-quote.svg" loading="lazy" alt=""/><div class="slider-heading">"Our experience with PBS technical support has been above and beyond. They're readily available to provide both support virtually as well as on site. We've built a very great relationship with the team."</div><div class="testimonial-name-wrap"><div class="text-size-regular">Emily Benz</div><div class="text-size-small">Engineer II, Process Development</div><div class="text-size-small color-grey">Viacyte Inc.</div></div></div><div fs-sliderdots-active="fs-sliderdots_active" fs-sliderdots-element="content" fs-sliderdots-remove="true" class="custom-dots"></div></div><div class="slider-item w-slide"><div class="slider-content-wrapper"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe7309b59484ef8_block-quote.svg" loading="lazy" alt=""/><div class="slider-heading">"Our experience with PBS technical support has been above and beyond. They're readily available to provide both support virtually as well as on site. We've built a very great relationship with the team."</div><div class="testimonial-name-wrap"><div class="text-size-regular">Emily Benz</div><div class="text-size-small">Engineer II, Process Development</div><div class="text-size-small color-grey">Viacyte Inc.</div></div></div><div fs-sliderdots-active="fs-sliderdots_active" fs-sliderdots-element="content" fs-sliderdots-remove="true" class="custom-dots"></div></div></div><div class="left-arrow w-slider-arrow-left"><div class="w-icon-slider-left"></div></div><div class="right-arrow w-slider-arrow-right"><div class="w-icon-slider-right"></div></div><div class="slide-nav w-slider-nav"></div></div></div></div></div><div id="request-block"></div><section id="service-form" class="section-service_form hideit"><div class="page-padding"><div id="service-support" class="conferences-container w-container"><div class="service-form-component"><h2 id="service-request-hdr" class="heading-14">Products and Services Request Form</h2><div 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id="w-node-cbf0de7d-90b4-1588-130a-194bcd2312a5-3a484eb3" class="service-item"><label for="last-name" class="field-label">Last Name <sup class="text-red">*</sup></label><input class="form-input is-select-input w-input" maxlength="256" name="Last-Name" data-name="Last Name" placeholder="" type="text" id="last-name"/></div><div id="w-node-cbf0de7d-90b4-1588-130a-194bcd2312a9-3a484eb3" class="service-item"><label for="title" class="field-label">Title <sup class="text-red">*</sup></label><input class="form-input is-select-input w-input" maxlength="256" name="Title" data-name="Title" placeholder="" type="text" id="title"/></div><div id="w-node-cbf0de7d-90b4-1588-130a-194bcd2312ad-3a484eb3" class="service-item"><label for="company" class="field-label">Company<sup class="text-red">*</sup></label><input class="form-input is-select-input w-input" maxlength="256" name="Company" data-name="Company" placeholder="" type="text" id="company"/></div><div id="w-node-cbf0de7d-90b4-1588-130a-194bcd2312b1-3a484eb3" class="service-item"><label for="phone" class="field-label">Phone <sup class="text-red">*</sup></label><input class="form-input is-select-input w-input" maxlength="256" name="Phone" data-name="Phone" placeholder="" type="number" id="phone" required=""/></div><div id="w-node-cbf0de7d-90b4-1588-130a-194bcd2312b5-3a484eb3" class="service-item"><label for="email" class="field-label">Email <sup class="text-red">*</sup></label><input class="form-input is-select-input w-input" maxlength="256" name="email" data-name="email" placeholder="" type="email" id="email" required=""/></div></div><div class="service-radio-wrapper"><div class="services-radio-wrapper"><div class="text-size-medium">Current Process Stage</div><div class="radio-button-wrapper"><label class="radio-button-field w-radio"><div class="w-form-formradioinput w-form-formradioinput--inputType-custom radio-button w-radio-input"></div><input type="radio" name="current" id="current" data-name="current" required="" style="opacity:0;position:absolute;z-index:-1" value="current"/><span class="form-radio w-form-label" for="current">Process Development</span></label><label class="radio-button-field w-radio"><div class="w-form-formradioinput w-form-formradioinput--inputType-custom radio-button w-radio-input"></div><input type="radio" name="current" id="current-2" data-name="current" style="opacity:0;position:absolute;z-index:-1" value="current"/><span class="form-radio w-form-label" for="current-2">Clinical Trails</span></label><label class="radio-button-field w-radio"><div class="w-form-formradioinput w-form-formradioinput--inputType-custom radio-button w-radio-input"></div><input type="radio" name="current" id="current-3" data-name="current" style="opacity:0;position:absolute;z-index:-1" value="current"/><span class="form-radio w-form-label" for="current-3">Commercial</span></label></div></div><div class="services-radio-wrapper"><div class="text-size-medium">Cell type(s) of interest (select all that apply)</div><div class="radio-button-wrapper"><label class="w-checkbox"><input type="checkbox" id="checkbox" name="checkbox" data-name="Checkbox" class="w-checkbox-input"/><span class="w-form-label" for="checkbox">PSC</span></label><label class="w-checkbox"><input type="checkbox" id="checkbox-6" name="checkbox-6" data-name="Checkbox 6" class="w-checkbox-input"/><span class="w-form-label" for="checkbox-6">MSC</span></label><label class="w-checkbox"><input type="checkbox" id="checkbox-5" name="checkbox-5" data-name="Checkbox 5" class="w-checkbox-input"/><span class="w-form-label" for="checkbox-5">CAR-T</span></label><label class="w-checkbox"><input type="checkbox" id="checkbox-4" name="checkbox-4" data-name="Checkbox 4" class="w-checkbox-input"/><span class="w-form-label" for="checkbox-4">Exosomes</span></label><label class="w-checkbox"><input type="checkbox" id="checkbox-4" name="checkbox-4" data-name="Checkbox 4" class="w-checkbox-input"/><span class="w-form-label" for="checkbox-4">Other (Enter answer Below):</span></label></div><textarea id="field-4" name="field-4" maxlength="5000" data-name="field" placeholder="" class="form-input is-text-area radio-form w-input"></textarea></div><div class="services-radio-wrapper"><div class="text-size-medium">General Comments</div><div class="radio-button-wrapper"><textarea id="general" name="General" maxlength="5000" data-name="General" placeholder="" required="" class="form-input is-text-area radio-form w-input"></textarea></div></div></div><input type="submit" data-wait="Please wait..." class="service-button w-button" value="Submit"/></form><div class="success-message w-form-done"><div class="text-size-medium">Thank you! 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