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Search results for: Gunter Spöcker
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text-center" style="font-size:1.6rem;">Search results for: Gunter Spöcker</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Workflow Based Inspection of Geometrical Adaptability from 3D CAD Models Considering Production Requirements</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tobias%20Huwer">Tobias Huwer</a>, <a href="https://publications.waset.org/abstracts/search?q=Thomas%20Bobek"> Thomas Bobek</a>, <a href="https://publications.waset.org/abstracts/search?q=Gunter%20Sp%C3%B6cker"> Gunter Spöcker</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Driving forces for enhancements in production are trends like digitalization and individualized production. Currently, such developments are restricted to assembly parts. Thus, complex freeform surfaces are not addressed in this context. The need for efficient use of resources and near-net-shape production will require individualized production of complex shaped workpieces. Due to variations between nominal model and actual geometry, this can lead to changes in operations in Computer-aided process planning (CAPP) to make CAPP manageable for an adaptive serial production. In this context, 3D CAD data can be a key to realizing that objective. Along with developments in the geometrical adaptation, a preceding inspection method based on CAD data is required to support the process planner by finding objective criteria to make decisions about the adaptive manufacturability of workpieces. Nowadays, this kind of decisions is depending on the experience-based knowledge of humans (e.g. process planners) and results in subjective decisions – leading to a variability of workpiece quality and potential failure in production. In this paper, we present an automatic part inspection method, based on design and measurement data, which evaluates actual geometries of single workpiece preforms. The aim is to automatically determine the suitability of the current shape for further machining, and to provide a basis for an objective decision about subsequent adaptive manufacturability. The proposed method is realized by a workflow-based approach, keeping in mind the requirements of industrial applications. Workflows are a well-known design method of standardized processes. Especially in applications like aerospace industry standardization and certification of processes are an important aspect. Function blocks, providing a standardized, event-driven abstraction to algorithms and data exchange, will be used for modeling and execution of inspection workflows. Each analysis step of the inspection, such as positioning of measurement data or checking of geometrical criteria, will be carried out by function blocks. One advantage of this approach is its flexibility to design workflows and to adapt algorithms specific to the application domain. In general, within the specified tolerance range it will be checked if a geometrical adaption is possible. The development of particular function blocks is predicated on workpiece specific information e.g. design data. Furthermore, for different product lifecycle phases, appropriate logics and decision criteria have to be considered. For example, tolerances for geometric deviations are different in type and size for new-part production compared to repair processes. In addition to function blocks, appropriate referencing systems are important. They need to support exact determination of position and orientation of the actual geometries to provide a basis for precise analysis. The presented approach provides an inspection methodology for adaptive and part-individual process chains. The analysis of each workpiece results in an inspection protocol and an objective decision about further manufacturability. A representative application domain is the product lifecycle of turbine blades containing a new-part production and a maintenance process. In both cases, a geometrical adaptation is required to calculate individual production data. In contrast to existing approaches, the proposed initial inspection method provides information to decide between different potential adaptive machining processes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adaptive" title="adaptive">adaptive</a>, <a href="https://publications.waset.org/abstracts/search?q=CAx" title=" CAx"> CAx</a>, <a href="https://publications.waset.org/abstracts/search?q=function%20blocks" title=" function blocks"> function blocks</a>, <a href="https://publications.waset.org/abstracts/search?q=turbomachinery" title=" turbomachinery"> turbomachinery</a> </p> <a href="https://publications.waset.org/abstracts/44434/workflow-based-inspection-of-geometrical-adaptability-from-3d-cad-models-considering-production-requirements" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44434.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">297</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> "Epitaph" Charles Mingus’ Foresight of Jazz</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Christel%20Elisabeth%20Bonin">Christel Elisabeth Bonin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The score of the 2 ½ hour ‘magnum opus’ named ‘Epitaph’ was reconstructed 10 years after Charles Mingus’ death in 1979. Most of the movements were probably composed in the late 1950s. As the finale was missing, Gunther Schuller, the conductor of the world premiere in 1989, decided to improvise one with the orchestra, using Mingus as a guide. The aim of this paper is to analyze ‘Main Score Part I ‘ and ‘Main Score Part II’ and to look into the score of Mingus’ reconstructed compositions under particular observation of the new finale, ‘Main Score Reprise’. There, Mingus left instructions for a return to the opening section of ‘Epitaph’. By examining ‘Epitaph’ in the historical context of Jazz between 1955 to 1967 and the 1980s and comparing the finale of ‘Epitaph’, created - or better said: improvised - by the musicians of the 1989 world premiere with the opening section, at first it will be interesting to discover at which point Gunther Schuller followed Mingus creative process and brought it to life in 1989. Finally, it will be speculated if Charles Mingus composition still represents a foresight of Jazz nearly 30 years after its creation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=epitaph" title="epitaph">epitaph</a>, <a href="https://publications.waset.org/abstracts/search?q=Charles%20Mingus" title=" Charles Mingus"> Charles Mingus</a>, <a href="https://publications.waset.org/abstracts/search?q=Gunter%20Schuller" title=" Gunter Schuller"> Gunter Schuller</a>, <a href="https://publications.waset.org/abstracts/search?q=jazz%20reception" title=" jazz reception"> jazz reception</a>, <a href="https://publications.waset.org/abstracts/search?q=bebop" title=" bebop"> bebop</a>, <a href="https://publications.waset.org/abstracts/search?q=hardbop" title=" hardbop"> hardbop</a>, <a href="https://publications.waset.org/abstracts/search?q=Duke%20Ellington" title=" Duke Ellington"> Duke Ellington</a>, <a href="https://publications.waset.org/abstracts/search?q=black" title=" black"> black</a>, <a href="https://publications.waset.org/abstracts/search?q=brown%20and%20beige" title=" brown and beige"> brown and beige</a>, <a href="https://publications.waset.org/abstracts/search?q=African-American%20music" title=" African-American music"> African-American music</a>, <a href="https://publications.waset.org/abstracts/search?q=free-jazz" title=" free-jazz"> free-jazz</a> </p> <a href="https://publications.waset.org/abstracts/41947/epitaph-charles-mingus-foresight-of-jazz" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41947.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">314</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Monitoring the Drying and Grinding Process during Production of Celitement through a NIR-Spectroscopy Based Approach</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Carolin%20Lutz">Carolin Lutz</a>, <a href="https://publications.waset.org/abstracts/search?q=J%C3%B6rg%20Matthes"> Jörg Matthes</a>, <a href="https://publications.waset.org/abstracts/search?q=Patrick%20Waibel"> Patrick Waibel</a>, <a href="https://publications.waset.org/abstracts/search?q=Ulrich%20Precht"> Ulrich Precht</a>, <a href="https://publications.waset.org/abstracts/search?q=Krassimir%20Garbev"> Krassimir Garbev</a>, <a href="https://publications.waset.org/abstracts/search?q=G%C3%BCnter%20Beuchle"> Günter Beuchle</a>, <a href="https://publications.waset.org/abstracts/search?q=Uwe%20Schweike"> Uwe Schweike</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20Stemmermann"> Peter Stemmermann</a>, <a href="https://publications.waset.org/abstracts/search?q=Hubert%20B.%20Keller"> Hubert B. Keller</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Online measurement of the product quality is a challenging task in cement production, especially in the production of Celitement, a novel environmentally friendly hydraulic binder. The mineralogy and chemical composition of clinker in ordinary Portland cement production is measured by X-ray diffraction (XRD) and X ray fluorescence (XRF), where only crystalline constituents can be detected. But only a small part of the Celitement components can be measured via XRD, because most constituents have an amorphous structure. This paper describes the development of algorithms suitable for an on-line monitoring of the final processing step of Celitement based on NIR-data. For calibration intermediate products were dried at different temperatures and ground for variable durations. The products were analyzed using XRD and thermogravimetric analyses together with NIR-spectroscopy to investigate the dependency between the drying and the milling processes on one and the NIR-signal on the other side. As a result, different characteristic parameters have been defined. A short overview of the Celitement process and the challenging tasks of the online measurement and evaluation of the product quality will be presented. Subsequently, methods for systematic development of near-infrared calibration models and the determination of the final calibration model will be introduced. The application of the model on experimental data illustrates that NIR-spectroscopy allows for a quick and sufficiently exact determination of crucial process parameters. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calibration%20model" title="calibration model">calibration model</a>, <a href="https://publications.waset.org/abstracts/search?q=celitement" title=" celitement"> celitement</a>, <a href="https://publications.waset.org/abstracts/search?q=cementitious%20material" title=" cementitious material"> cementitious material</a>, <a href="https://publications.waset.org/abstracts/search?q=NIR%20spectroscopy" title=" NIR spectroscopy"> NIR spectroscopy</a> </p> <a href="https://publications.waset.org/abstracts/35212/monitoring-the-drying-and-grinding-process-during-production-of-celitement-through-a-nir-spectroscopy-based-approach" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35212.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">500</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> A Randomized Controlled Intervention Study of the Effect of Music Training on Mathematical and Working Memory Performances</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ingo%20Roden">Ingo Roden</a>, <a href="https://publications.waset.org/abstracts/search?q=Stefana%20Lupu"> Stefana Lupu</a>, <a href="https://publications.waset.org/abstracts/search?q=Mara%20Krone"> Mara Krone</a>, <a href="https://publications.waset.org/abstracts/search?q=Jasmin%20Chantah"> Jasmin Chantah</a>, <a href="https://publications.waset.org/abstracts/search?q=Gunter%20Kreutz"> Gunter Kreutz</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephan%20Bongard"> Stephan Bongard</a>, <a href="https://publications.waset.org/abstracts/search?q=Dietmar%20Grube"> Dietmar Grube</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present experimental study examined the effects of music and math training on mathematical skills and visuospatial working memory capacity in kindergarten children. For this purpose, N = 54 children (mean age: 5.46 years; SD = .29) were randomly assigned to three groups. Children in the music group (n = 18) received weekly sessions of 60 min music training over a period of eight weeks, whereas children in the math group (n = 18) received the same amount of training focusing on mathematical basic skills, such as numeracy skills, quantity comparison, and counting objectives. The third group of children (n = 18) served as waiting controls. The groups were matched for sex, age, IQ and previous music experiences at baseline. Pre-Post intervention measurements revealed a significant interaction effect of group x time, showing that children in both music and math groups significantly improved their early numeracy skills, whereas children in the control group did not. No significant differences between groups were observed for the visuospatial working memory performances. These results confirm and extend previous findings on transfer effects of music training on mathematical abilities and visuospatial working memory capacity. They show that music and math interventions are similarly effective to enhance children’s mathematical skills. More research is necessary to establish, whether cognitive transfer effects arising from music interventions might facilitate children’s transition from kindergarten to first-grade. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=music%20training" title="music training">music training</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20skills" title=" mathematical skills"> mathematical skills</a>, <a href="https://publications.waset.org/abstracts/search?q=working%20memory" title=" working memory"> working memory</a>, <a href="https://publications.waset.org/abstracts/search?q=transfer" title=" transfer"> transfer</a> </p> <a href="https://publications.waset.org/abstracts/98097/a-randomized-controlled-intervention-study-of-the-effect-of-music-training-on-mathematical-and-working-memory-performances" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98097.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">272</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Effects of Music Training on Social-Emotional Development and Basic Musical Skills: Findings from a Longitudinal Study with German and Migrant Children</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Stefana%20Francisca%20Lupu">Stefana Francisca Lupu</a>, <a href="https://publications.waset.org/abstracts/search?q=Jasmin%20Chantah"> Jasmin Chantah</a>, <a href="https://publications.waset.org/abstracts/search?q=Mara%20Krone"> Mara Krone</a>, <a href="https://publications.waset.org/abstracts/search?q=Ingo%20Roden"> Ingo Roden</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephan%20Bongard"> Stephan Bongard</a>, <a href="https://publications.waset.org/abstracts/search?q=Gunter%20Kreutz"> Gunter Kreutz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Long-term music interventions could enhance both musical and nonmusical skills. The present study was designed to explore cognitive, socio-emotional, and musical development in a longitudinal setting. Third-graders (N = 184: 87 male, 97 female; mean age = 8.61 years; 115 native German and 69 migrant children) were randomly assigned to two intervention groups (music and maths) and a control group over a period of one school-year. At baseline, children in these groups were similar in basic cognitive skills, with a trend of advantage in the control group. Dependent measures included the culture fair intelligence test CFT 20-R; the questionnaire of emotional and social school experience for grade 3 and 4 (FEESS 3-4), the test of resources in childhood and adolescence (FRKJ 8-16), the test of language proficiency for German native and non-native primary school children (SFD 3), the reading comprehension test (ELFE 1-6), the German math test (DEMAT 3+) and the intermediate measures of music audiation (IMMA). Data were collected two times at the beginning (T1) and at the end of the school year (T2). A third measurement (T3) followed after a six months retention period. Data from baseline and post-intervention measurements are currently being analyzed. Preliminary results of all three measurements will be presented at the conference. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=musical%20training" title="musical training">musical training</a>, <a href="https://publications.waset.org/abstracts/search?q=primary-school%20German%20and%20migrant%20children" title=" primary-school German and migrant children"> primary-school German and migrant children</a>, <a href="https://publications.waset.org/abstracts/search?q=socio-emotional%20skills" title=" socio-emotional skills"> socio-emotional skills</a>, <a href="https://publications.waset.org/abstracts/search?q=transfer" title=" transfer"> transfer</a> </p> <a href="https://publications.waset.org/abstracts/99617/effects-of-music-training-on-social-emotional-development-and-basic-musical-skills-findings-from-a-longitudinal-study-with-german-and-migrant-children" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99617.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">245</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Observed Changes in Constructed Precipitation at High Resolution in Southern Vietnam</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nguyen%20Tien%20Thanh">Nguyen Tien Thanh</a>, <a href="https://publications.waset.org/abstracts/search?q=G%C3%BCnter%20Meon"> Günter Meon</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Precipitation plays a key role in water cycle, defining the local climatic conditions and in ecosystem. It is also an important input parameter for water resources management and hydrologic models. With spatial continuous data, a certainty of discharge predictions or other environmental factors is unquestionably better than without. This is, however, not always willingly available to acquire for a small basin, especially for coastal region in Vietnam due to a low network of meteorological stations (30 stations) on long coast of 3260 km2. Furthermore, available gridded precipitation datasets are not fine enough when applying to hydrologic models. Under conditions of global warming, an application of spatial interpolation methods is a crucial for the climate change impact studies to obtain the spatial continuous data. In recent research projects, although some methods can perform better than others do, no methods draw the best results for all cases. The objective of this paper therefore, is to investigate different spatial interpolation methods for daily precipitation over a small basin (approximately 400 km2) located in coastal region, Southern Vietnam and find out the most efficient interpolation method on this catchment. The five different interpolation methods consisting of cressman, ordinary kriging, regression kriging, dual kriging and inverse distance weighting have been applied to identify the best method for the area of study on the spatio-temporal scale (daily, 10 km x 10 km). A 30-year precipitation database was created and merged into available gridded datasets. Finally, observed changes in constructed precipitation were performed. The results demonstrate that the method of ordinary kriging interpolation is an effective approach to analyze the daily precipitation. The mixed trends of increasing and decreasing monthly, seasonal and annual precipitation have documented at significant levels. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=interpolation" title="interpolation">interpolation</a>, <a href="https://publications.waset.org/abstracts/search?q=precipitation" title=" precipitation"> precipitation</a>, <a href="https://publications.waset.org/abstracts/search?q=trend" title=" trend"> trend</a>, <a href="https://publications.waset.org/abstracts/search?q=vietnam" title=" vietnam"> vietnam</a> </p> <a href="https://publications.waset.org/abstracts/41642/observed-changes-in-constructed-precipitation-at-high-resolution-in-southern-vietnam" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41642.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">275</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> In-Situ Studies of Cyclohexane Oxidation Using Laser Raman Spectroscopy for the Refinement of Mechanism Based Kinetic Models</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Christine%20Fr%C3%A4ulin">Christine Fräulin</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniela%20Schurr"> Daniela Schurr</a>, <a href="https://publications.waset.org/abstracts/search?q=Hamed%20Shahidi%20Rad"> Hamed Shahidi Rad</a>, <a href="https://publications.waset.org/abstracts/search?q=Gerrit%20Waters"> Gerrit Waters</a>, <a href="https://publications.waset.org/abstracts/search?q=G%C3%BCnter%20Rinke"> Günter Rinke</a>, <a href="https://publications.waset.org/abstracts/search?q=Roland%20Dittmeyer"> Roland Dittmeyer</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Nilles"> Michael Nilles</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The reaction mechanisms of many liquid-phase reactions in organic chemistry have not yet been sufficiently clarified. Process conditions of several hundred degrees celsius and pressures to ten megapascals complicate the sampling and the determination of kinetic data. Space resolved in-situ measurements promises new insights. A non-invasive in-situ measurement technique has the advantages that no sample preparation is necessary, there is no change in sample mixture before analysis and the sampling do no lead to interventions in the flow. Thus, the goal of our research was the development of a contact-free spatially resolved measurement technique for kinetic studies of liquid phase reaction under process conditions. Therefore we used laser Raman spectroscopy combined with an optical transparent microchannel reactor. To show the performance of the system we choose the oxidation of cyclohexane as sample reaction. Cyclohexane oxidation is an economically important process. The products are intermediates for caprolactam and adipic acid, which are starting materials for polyamide 6 and 6.6 production. To maintain high selectivities of 70 to 90 %, the reaction is performed in industry at a low conversion of about six percent. As Raman spectroscopy is usually very selective but not very sensitive the detection of the small product concentration in cyclohexane oxidation is quite challenging. To meet these requirements, an optical experimental setup was optimized to determine the concentrations by laser Raman spectroscopy with respect to good detection sensitivity. With this measurement technique space resolved kinetic studies of uncatalysed and homogeneous catalyzed cyclohexane oxidation were carried out to obtain details about the reaction mechanism. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=in-situ%20laser%20raman%20spectroscopy" title="in-situ laser raman spectroscopy">in-situ laser raman spectroscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=space%20resolved%20kinetic%20measurements" title=" space resolved kinetic measurements"> space resolved kinetic measurements</a>, <a href="https://publications.waset.org/abstracts/search?q=homogeneous%20catalysis" title=" homogeneous catalysis"> homogeneous catalysis</a>, <a href="https://publications.waset.org/abstracts/search?q=chemistry" title=" chemistry"> chemistry</a> </p> <a href="https://publications.waset.org/abstracts/2600/in-situ-studies-of-cyclohexane-oxidation-using-laser-raman-spectroscopy-for-the-refinement-of-mechanism-based-kinetic-models" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2600.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">334</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Numerical Analysis of the Response of Thin Flexible Membranes to Free Surface Water Flow</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mahtab%20Makaremi%20Masouleh">Mahtab Makaremi Masouleh</a>, <a href="https://publications.waset.org/abstracts/search?q=G%C3%BCnter%20Wozniak"> Günter Wozniak</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This work is part of a major research project concerning the design of a light temporary installable textile flood control structure. The motivation for this work is the great need of applying light structures for the protection of coastal areas from detrimental effects of rapid water runoff. The prime objective of the study is the numerical analysis of the interaction among free surface water flow and slender shaped pliable structures, playing a key role in safety performance of the intended system. First, the behavior of down scale membrane is examined under hydrostatic pressure by the Abaqus explicit solver, which is part of the finite element based commercially available SIMULIA software. Then the procedure to achieve a stable and convergent solution for strongly coupled media including fluids and structures is explained. A partitioned strategy is imposed to make both structures and fluids be discretized and solved with appropriate formulations and solvers. In this regard, finite element method is again selected to analyze the structural domain. Moreover, computational fluid dynamics algorithms are introduced for solutions in flow domains by means of a commercial package of Star CCM+. Likewise, SIMULIA co-simulation engine and an implicit coupling algorithm, which are available communication tools in commercial package of the Star CCM+, enable powerful transmission of data between two applied codes. This approach is discussed for two different cases and compared with available experimental records. In one case, the down scale membrane interacts with open channel flow, where the flow velocity increases with time. The second case illustrates, how the full scale flexible flood barrier behaves when a massive flotsam is accelerated towards it. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20formulation" title="finite element formulation">finite element formulation</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20volume%20algorithm" title=" finite volume algorithm"> finite volume algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid-structure%20interaction" title=" fluid-structure interaction"> fluid-structure interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=light%20pliable%20structure" title=" light pliable structure"> light pliable structure</a>, <a href="https://publications.waset.org/abstracts/search?q=VOF%20multiphase%20model" title=" VOF multiphase model"> VOF multiphase model</a> </p> <a href="https://publications.waset.org/abstracts/78889/numerical-analysis-of-the-response-of-thin-flexible-membranes-to-free-surface-water-flow" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/78889.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">186</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> In Vivo Investigation of microRNA Expression and Function at the Mammalian Synapse by AGO-APP</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Surbhi%20Surbhi">Surbhi Surbhi</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Erni"> Andrea Erni</a>, <a href="https://publications.waset.org/abstracts/search?q=Gunter%20Meister"> Gunter Meister</a>, <a href="https://publications.waset.org/abstracts/search?q=Harold%20Cremer"> Harold Cremer</a>, <a href="https://publications.waset.org/abstracts/search?q=Christophe%20Beclin"> Christophe Beclin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> MicroRNAs (miRNAs) are short 20-23 nucleotide long non-coding RNAs; there are 2605 miRNA in humans and 1936 miRNA in mouse in total (miRBase). The nervous system expresses the most abundant miRNA and most diverse. MiRNAs play a role in many steps during neurogenesis, like cell proliferation, differentiation, neural patterning, axon pathfinding, etc. Moreover, in vitro studies suggested a role in the regulation of local translation at the synapse, thus controlling neuronal plasticity. However, due to the specific structure of miRNA molecules, an in-vivo confirmation of the general role of miRNAs in the control of neuronal plasticity is still pending. For example, their small size and their high level of sequence homology make difficult the analysis of their cellular and sub-cellular localization in-vivo by in-situ hybridization. Moreover, it was found that only 40% of the expressed miRNA molecules in a cell are included in RNA-Induced Silencing Complexes (RISC) and, therefore, involved in inhibitory interactions while the rest is silent. Definitively, the development of new tools is needed to have a better understanding of the cellular function of miRNAs, in particular their role in neuronal plasticity. Here we describe a new technique called in-vivo AGO-APP designed to investigate miRNA expression and function in-vivo. This technique is based on the expression of a small peptide derived from the human RISC-complex protein TNRC6B, called T6B, which binds all known Argonaute (Ago) proteins with high affinity allowing the efficient immunoprecipitation of AGO-bound miRNAs. We have generated two transgenic mouse lines conditionally expressing T6B either ubiquitously in the cell or targeted at the synapse. A comparison of the repertoire of miRNAs immuno-precipitated from mature neurons of both mouse lines will provide us with a list of miRNAs showing a specific activity at the synapse. The physiological role of these miRNAs will be subsequently addressed through gain and loss of function experiments. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=RNA-induced%20silencing%20complexes" title="RNA-induced silencing complexes">RNA-induced silencing complexes</a>, <a href="https://publications.waset.org/abstracts/search?q=TNRC6B" title=" TNRC6B"> TNRC6B</a>, <a href="https://publications.waset.org/abstracts/search?q=miRNA" title=" miRNA"> miRNA</a>, <a href="https://publications.waset.org/abstracts/search?q=argonaute" title=" argonaute"> argonaute</a>, <a href="https://publications.waset.org/abstracts/search?q=synapse" title=" synapse"> synapse</a>, <a href="https://publications.waset.org/abstracts/search?q=neuronal%20plasticity" title=" neuronal plasticity"> neuronal plasticity</a>, <a href="https://publications.waset.org/abstracts/search?q=neurogenesis" title=" neurogenesis"> neurogenesis</a> </p> <a href="https://publications.waset.org/abstracts/155817/in-vivo-investigation-of-microrna-expression-and-function-at-the-mammalian-synapse-by-ago-app" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/155817.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">131</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Development of an Implicit Coupled Partitioned Model for the Prediction of the Behavior of a Flexible Slender Shaped Membrane in Interaction with Free Surface Flow under the Influence of a Moving Flotsam</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mahtab%20Makaremi%20Masouleh">Mahtab Makaremi Masouleh</a>, <a href="https://publications.waset.org/abstracts/search?q=G%C3%BCnter%20Wozniak"> Günter Wozniak</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This research is part of an interdisciplinary project, promoting the design of a light temporary installable textile defence system against flood. In case river water levels increase abruptly especially in winter time, one can expect massive extra load on a textile protective structure in term of impact as a result of floating debris and even tree trunks. Estimation of this impulsive force on such structures is of a great importance, as it can ensure the reliability of the design in critical cases. This fact provides the motivation for the numerical analysis of a fluid structure interaction application, comprising flexible slender shaped and free-surface water flow, where an accelerated heavy flotsam tends to approach the membrane. In this context, the analysis on both the behavior of the flexible membrane and its interaction with moving flotsam is conducted by finite elements based solvers of the explicit solver and implicit Abacus solver available as products of SIMULIA software. On the other hand, a study on how free surface water flow behaves in response to moving structures, has been investigated using the finite volume solver of Star CCM+ from Siemens PLM Software. An automatic communication tool (CSE, SIMULIA Co-Simulation Engine) and the implementation of an effective partitioned strategy in form of an implicit coupling algorithm makes it possible for partitioned domains to be interconnected powerfully. The applied procedure ensures stability and convergence in the solution of these complicated issues, albeit with high computational cost; however, the other complexity of this study stems from mesh criterion in the fluid domain, where the two structures approach each other. This contribution presents the approaches for the establishment of a convergent numerical solution and compares the results with experimental findings. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=co-simulation" title="co-simulation">co-simulation</a>, <a href="https://publications.waset.org/abstracts/search?q=flexible%20thin%20structure" title=" flexible thin structure"> flexible thin structure</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid-structure%20interaction" title=" fluid-structure interaction"> fluid-structure interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=implicit%20coupling%20algorithm" title=" implicit coupling algorithm"> implicit coupling algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=moving%20flotsam" title=" moving flotsam"> moving flotsam</a> </p> <a href="https://publications.waset.org/abstracts/78832/development-of-an-implicit-coupled-partitioned-model-for-the-prediction-of-the-behavior-of-a-flexible-slender-shaped-membrane-in-interaction-with-free-surface-flow-under-the-influence-of-a-moving-flotsam" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/78832.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">389</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" 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