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class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by olufunmilayo adejumo</h3></div><div class="js-work-strip profile--work_container" data-work-id="100046847"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100046847/Plasmid_DNA_mediated_vancomycin_resistant_Staphylococcus_aureus_VRSA_from_cases_of_urinary_tract_infection"><img alt="Research paper thumbnail of Plasmid DNA mediated vancomycin-resistant Staphylococcus aureus (VRSA) from cases of urinary tract infection" class="work-thumbnail" src="https://attachments.academia-assets.com/100975674/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100046847/Plasmid_DNA_mediated_vancomycin_resistant_Staphylococcus_aureus_VRSA_from_cases_of_urinary_tract_infection">Plasmid DNA mediated vancomycin-resistant Staphylococcus aureus (VRSA) from cases of urinary tract infection</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Bioresources</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrin...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrinsic virulence. Sixty isolates of Staphylococcus aureus tested positive as vancomycin possessive isolates on Brain Heart Infusion Agar medium fortified with 6 μg/mL vancomycin from 100 clinical samples of urine from patients with cases of UTIs via agar diffusion method. Standard 30 μg vancomycin disc served as control. Increase in zones of growth inhibition in relation to vancomycin concentrations was noticed in some of the isolates while it was reversed in others, despite the increase in concentration. Typed strain was susceptible to six concentrations of vancomycin exposed and to the control. Thirty one of the sixty isolates were resistant to vancomycin control. Resistant isolates from standard vancomycin discs were then subjected to molecular investigation. Of the 31 isolates exposed to gel electrophoresis, 14 (47%)elicited plasmids of varied molecular weights ranging from 0.79-23.13 k...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="84f769f40848102896df17e01b89335c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":100975674,"asset_id":100046847,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/100975674/download_file?st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100046847"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100046847"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100046847; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100046847]").text(description); $(".js-view-count[data-work-id=100046847]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100046847; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100046847']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100046847, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "84f769f40848102896df17e01b89335c" } } $('.js-work-strip[data-work-id=100046847]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100046847,"title":"Plasmid DNA mediated vancomycin-resistant Staphylococcus aureus (VRSA) from cases of urinary tract infection","translated_title":"","metadata":{"abstract":"Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrinsic virulence. 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Of the 31 isolates exposed to gel electrophoresis, 14 (47%)elicited plasmids of varied molecular weights ranging from 0.79-23.13 k...","publisher":"African Journals Online (AJOL)","publication_name":"Journal of Pharmacy \u0026amp; Bioresources"},"translated_abstract":"Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrinsic virulence. Sixty isolates of Staphylococcus aureus tested positive as vancomycin possessive isolates on Brain Heart Infusion Agar medium fortified with 6 μg/mL vancomycin from 100 clinical samples of urine from patients with cases of UTIs via agar diffusion method. Standard 30 μg vancomycin disc served as control. Increase in zones of growth inhibition in relation to vancomycin concentrations was noticed in some of the isolates while it was reversed in others, despite the increase in concentration. Typed strain was susceptible to six concentrations of vancomycin exposed and to the control. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96013201"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96013201/Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria"><img alt="Research paper thumbnail of Bacteriological evaluation of instant noodles stored under sub-optimal conditions from selected markets in Sagamu- Ibafo axis of Ogun State, Nigeria" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96013201/Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria">Bacteriological evaluation of instant noodles stored under sub-optimal conditions from selected markets in Sagamu- Ibafo axis of Ogun State, Nigeria</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Bioresources</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical s...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical status, and resistance of the isolates to conventional antibiotics, in addition to pH. These brands were cultured on plate count agar for bacterial enumeration while isolates were challenged on selective media for bacteria of clinical status. The antibiogram was determined using standard methods. The pH varied from acidic (4.92) as shown in GPJ 3 to closely neutral (6.94) as recorded in HWJ 2. TTJ1 had the lowest average bacteria count of 1.6 x 103 while BFJ5 with 6.3 x 105 counts was the highest. Prevalence of isolates of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa varied in the ratio 40:30:30. Of the 40 samples, 8 of the 16 Escherichia coli were resistant to gentamicin, ciprofloxacin, and Augmentin, 7 of the 12 Staphylococcus aureus elicited resistance to ampicillin and cotrimoxazole while 8 of the Pseudomonas aeruginosa were resistant to meropenem, cotrimoxazole...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96013201"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96013201"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96013201; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96013201]").text(description); $(".js-view-count[data-work-id=96013201]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96013201; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96013201']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96013201, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=96013201]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96013201,"title":"Bacteriological evaluation of instant noodles stored under sub-optimal conditions from selected markets in Sagamu- Ibafo axis of Ogun State, Nigeria","translated_title":"","metadata":{"abstract":"This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical status, and resistance of the isolates to conventional antibiotics, in addition to pH. These brands were cultured on plate count agar for bacterial enumeration while isolates were challenged on selective media for bacteria of clinical status. The antibiogram was determined using standard methods. The pH varied from acidic (4.92) as shown in GPJ 3 to closely neutral (6.94) as recorded in HWJ 2. TTJ1 had the lowest average bacteria count of 1.6 x 103 while BFJ5 with 6.3 x 105 counts was the highest. Prevalence of isolates of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa varied in the ratio 40:30:30. Of the 40 samples, 8 of the 16 Escherichia coli were resistant to gentamicin, ciprofloxacin, and Augmentin, 7 of the 12 Staphylococcus aureus elicited resistance to ampicillin and cotrimoxazole while 8 of the Pseudomonas aeruginosa were resistant to meropenem, cotrimoxazole...","publisher":"African Journals Online (AJOL)","publication_name":"Journal of Pharmacy \u0026amp; Bioresources"},"translated_abstract":"This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical status, and resistance of the isolates to conventional antibiotics, in addition to pH. These brands were cultured on plate count agar for bacterial enumeration while isolates were challenged on selective media for bacteria of clinical status. The antibiogram was determined using standard methods. The pH varied from acidic (4.92) as shown in GPJ 3 to closely neutral (6.94) as recorded in HWJ 2. TTJ1 had the lowest average bacteria count of 1.6 x 103 while BFJ5 with 6.3 x 105 counts was the highest. Prevalence of isolates of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa varied in the ratio 40:30:30. Of the 40 samples, 8 of the 16 Escherichia coli were resistant to gentamicin, ciprofloxacin, and Augmentin, 7 of the 12 Staphylococcus aureus elicited resistance to ampicillin and cotrimoxazole while 8 of the Pseudomonas aeruginosa were resistant to meropenem, cotrimoxazole...","internal_url":"https://www.academia.edu/96013201/Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria","translated_internal_url":"","created_at":"2023-01-30T22:39:22.876-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[],"research_interests":[{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[{"id":28547082,"url":"https://www.ajol.info/index.php/jpb/article/download/238797/225684"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96013176"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96013176/Quality_Characteristics_and_%CE%91lpha_Tocopherol_Content_of_Shea_Butter_Samples_from_Selected_Markets_Within_Three_Southwestern_States_of_Nigeria"><img alt="Research paper thumbnail of Quality Characteristics and Αlpha-Tocopherol Content of Shea Butter Samples from Selected Markets Within Three Southwestern States of Nigeria" class="work-thumbnail" src="https://attachments.academia-assets.com/98031285/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96013176/Quality_Characteristics_and_%CE%91lpha_Tocopherol_Content_of_Shea_Butter_Samples_from_Selected_Markets_Within_Three_Southwestern_States_of_Nigeria">Quality Characteristics and Αlpha-Tocopherol Content of Shea Butter Samples from Selected Markets Within Three Southwestern States of Nigeria</a></div><div class="wp-workCard_item"><span>Dhaka University Journal of Pharmaceutical Sciences</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC quality characteristics and α-tocopherol content. The α-tocopherol was determined by RP-HPLC and mg per serving and % daily values (% DV) were estimated. The ranges of acid value (AV) [mgKOH/kg], free fatty acid (FFA) [%], peroxide value (PV) [meqO2/Kg], iodine value (IV) [gI2/100g] and saponification value (SV) [mgKOH/g] were 2.20- 2.59, 1.15-1.30, 0.75-0.95, 44.43-47.85 and 170.08-259.30, respectively. The -tocopherol had a retention time of 3.561 minutes and its content ranged from 1.15-2.60 mg/100 g in the samples, but 5.25 mg/100 g for the laboratory sample. Milligram (mg) per serving and percentage dietary value were 0.16-0.74 and 1.07-4.93, respectively. Quality characteristics varied significantly (p &lt; 0.05) both within and across different markets. Based on the PV and IV results, the marketed shea butter samples may be both food and industry-grade but failed the FFA test. S...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="136405377a7f9fd5bd85ff69677e37e7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98031285,"asset_id":96013176,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98031285/download_file?st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96013176"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96013176"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96013176; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96013176]").text(description); $(".js-view-count[data-work-id=96013176]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96013176; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96013176']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96013176, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "136405377a7f9fd5bd85ff69677e37e7" } } $('.js-work-strip[data-work-id=96013176]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96013176,"title":"Quality Characteristics and Αlpha-Tocopherol Content of Shea Butter Samples from Selected Markets Within Three Southwestern States of Nigeria","translated_title":"","metadata":{"abstract":"Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC quality characteristics and α-tocopherol content. The α-tocopherol was determined by RP-HPLC and mg per serving and % daily values (% DV) were estimated. The ranges of acid value (AV) [mgKOH/kg], free fatty acid (FFA) [%], peroxide value (PV) [meqO2/Kg], iodine value (IV) [gI2/100g] and saponification value (SV) [mgKOH/g] were 2.20- 2.59, 1.15-1.30, 0.75-0.95, 44.43-47.85 and 170.08-259.30, respectively. The -tocopherol had a retention time of 3.561 minutes and its content ranged from 1.15-2.60 mg/100 g in the samples, but 5.25 mg/100 g for the laboratory sample. Milligram (mg) per serving and percentage dietary value were 0.16-0.74 and 1.07-4.93, respectively. Quality characteristics varied significantly (p \u0026lt; 0.05) both within and across different markets. Based on the PV and IV results, the marketed shea butter samples may be both food and industry-grade but failed the FFA test. S...","publisher":"Bangladesh Journals Online (JOL)","publication_name":"Dhaka University Journal of Pharmaceutical Sciences"},"translated_abstract":"Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC quality characteristics and α-tocopherol content. The α-tocopherol was determined by RP-HPLC and mg per serving and % daily values (% DV) were estimated. The ranges of acid value (AV) [mgKOH/kg], free fatty acid (FFA) [%], peroxide value (PV) [meqO2/Kg], iodine value (IV) [gI2/100g] and saponification value (SV) [mgKOH/g] were 2.20- 2.59, 1.15-1.30, 0.75-0.95, 44.43-47.85 and 170.08-259.30, respectively. The -tocopherol had a retention time of 3.561 minutes and its content ranged from 1.15-2.60 mg/100 g in the samples, but 5.25 mg/100 g for the laboratory sample. Milligram (mg) per serving and percentage dietary value were 0.16-0.74 and 1.07-4.93, respectively. Quality characteristics varied significantly (p \u0026lt; 0.05) both within and across different markets. Based on the PV and IV results, the marketed shea butter samples may be both food and industry-grade but failed the FFA test. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="77856671"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/77856671/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls"><img alt="Research paper thumbnail of Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls" class="work-thumbnail" src="https://attachments.academia-assets.com/85104754/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/77856671/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls">Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls</a></div><div class="wp-workCard_item"><span>Journal of Clinical Pharmacy and Therapeutics</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="48bce6cd091db48e97638bb1707d52bc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":85104754,"asset_id":77856671,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/85104754/download_file?st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="77856671"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="77856671"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 77856671; 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Crude methanolic extracts of the leaves were screened for phytochemicals after which they were tested in vitro for activity against clinical isolates of Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa, Proteus vulgaris, Bacillus subtilis, Enterobacter aerogenes, Aspergillus niger, A, flavus and Candida albicans. Phytochemicals present in the extracts included saponins, alkaloids, anthraquinones, tannins, flavonoids and cardiac glycosides. These extracts also showed varying degrees of activity against tested organisms at a concentration range of 15.6 to 500 mg/ml. However, S. acuta showed activity against P. vulgaris, E. aerogenes and As. flavus only. The MIC of the extracts against test organisms ranged from 31.25 to 250 mg/ml. The significant antimicrob...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="be282564bd44b870871117474e7259e1" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":80500178,"asset_id":70966689,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/80500178/download_file?st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="70966689"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="70966689"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 70966689; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=70966689]").text(description); $(".js-view-count[data-work-id=70966689]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 70966689; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='70966689']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 70966689, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "be282564bd44b870871117474e7259e1" } } $('.js-work-strip[data-work-id=70966689]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":70966689,"title":"Phytochemistry and In vitro Antimicrobial Activity of Five Plant Species against Nine Common Human Pathogens","translated_title":"","metadata":{"abstract":"Momordica charantia, Senna podocarpa, Senna alata, Ocimum gratissimum, and Sida acuta which have reportedly been used in folklore for the treatment of various diseases were studied for their antimicrobial activity. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65217168"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65217168/Detoxification_and_nutritional_enrichment_of_cassava_waste_pulp_using_Rhizopus_oligosporus_and_Aspergillus_niger"><img alt="Research paper thumbnail of Detoxification and nutritional enrichment of cassava waste pulp using Rhizopus oligosporus and Aspergillus niger" class="work-thumbnail" src="https://attachments.academia-assets.com/76914523/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65217168/Detoxification_and_nutritional_enrichment_of_cassava_waste_pulp_using_Rhizopus_oligosporus_and_Aspergillus_niger">Detoxification and nutritional enrichment of cassava waste pulp using Rhizopus oligosporus and Aspergillus niger</a></div><div class="wp-workCard_item"><span>The Annals of the University Dunarea de Jos of Galati. Fascicle VI - Food Technology</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present study evaluated the detoxification and nutritional enrichment potentials of the ferme...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present study evaluated the detoxification and nutritional enrichment potentials of the fermented cassava waste pulp obtained through different processing methods of sweet (S) and bitter (B) cassava varieties by fermentation with Rhizopus oligosporus and Aspergillus niger. Four batches [two with both bark and cortex of the tuber removed (S- and B-), two with bark only removed (S+ and B+)] of cassava waste pulp (CWP) were produced from each of S and B varieties. CWP from the four treatments were then subjected to Rhizopus oligosporus, Aspergillus niger, and natural fermentation. Cyanide (mg HCN/kg), phytate (mg/100g), tannin (mg/100g), pH, crude protein (N X6.25) (%), ash (%), Fe, P, K and Ca (mg/100g) content of the unfermented and fermented CWP were determined using standard procedures. The range of the reduction (%) in cyanide content for Rhizopus oligosporus fermented CWP (RCWP), Aspergillus niger fermented CWP (ACWP), and naturally fermented CWP (NCWP) were 86.24 – 91.95, 79...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0ed0237e3743c5ae6f2ccfb630eb0dbd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":76914523,"asset_id":65217168,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/76914523/download_file?st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65217168"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65217168"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65217168; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65217168]").text(description); $(".js-view-count[data-work-id=65217168]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65217168; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65217168']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 65217168, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0ed0237e3743c5ae6f2ccfb630eb0dbd" } } $('.js-work-strip[data-work-id=65217168]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65217168,"title":"Detoxification and nutritional enrichment of cassava waste pulp using Rhizopus oligosporus and Aspergillus niger","translated_title":"","metadata":{"abstract":"The present study evaluated the detoxification and nutritional enrichment potentials of the fermented cassava waste pulp obtained through different processing methods of sweet (S) and bitter (B) cassava varieties by fermentation with Rhizopus oligosporus and Aspergillus niger. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65217120"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65217120/Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria"><img alt="Research paper thumbnail of Application of Atomic Absorption Spectroscopy in the Determination of the Elemental Composition of Chanca piedra (Stone Breaker Leaf) Growing in Iwo, South West Nigeria" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65217120/Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria">Application of Atomic Absorption Spectroscopy in the Determination of the Elemental Composition of Chanca piedra (Stone Breaker Leaf) Growing in Iwo, South West Nigeria</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus amarus (Euphorbiaceae) was determined using atomic absorption spectroscopy, AAS. Chanca piedra a tropical medicinal plant, is reportedly useful in blocking kidney stone formation and has anti-hepatitis B activity. The acid digested samples were subjected to AAS analysis. The atomic absorption spectrophotometer (PG-990) is a fully automated instrument used in the flame configuration option, controlled by a personal computer, with Microsoft windows as the operating system. Results showed that manganese (Mn) (228.9 ± 3.3 mg/kg), zinc (Zn) (41.7 ± 0.9 mg/kg), iron (Fe) (459.3 ± 3.3 mg/kg), calcium (Ca) (521.9 ± 1.8 mg/kg) and magnesium (Mg) (397.4 ± 1.3 mg/kg) were present in the plant. These high concentrations of calcium, iron and magnesium in this plant should be useful for electrolyte balance, enhancement of growth, bone and teeth formation, and activation of enzyme reactions. It should a...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65217120"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65217120"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65217120; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65217120]").text(description); $(".js-view-count[data-work-id=65217120]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65217120; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65217120']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 65217120, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65217120]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65217120,"title":"Application of Atomic Absorption Spectroscopy in the Determination of the Elemental Composition of Chanca piedra (Stone Breaker Leaf) Growing in Iwo, South West Nigeria","translated_title":"","metadata":{"abstract":"The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus amarus (Euphorbiaceae) was determined using atomic absorption spectroscopy, AAS. 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It should a...","publication_date":{"day":null,"month":null,"year":2018,"errors":{}}},"translated_abstract":"The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus amarus (Euphorbiaceae) was determined using atomic absorption spectroscopy, AAS. Chanca piedra a tropical medicinal plant, is reportedly useful in blocking kidney stone formation and has anti-hepatitis B activity. The acid digested samples were subjected to AAS analysis. The atomic absorption spectrophotometer (PG-990) is a fully automated instrument used in the flame configuration option, controlled by a personal computer, with Microsoft windows as the operating system. Results showed that manganese (Mn) (228.9 ± 3.3 mg/kg), zinc (Zn) (41.7 ± 0.9 mg/kg), iron (Fe) (459.3 ± 3.3 mg/kg), calcium (Ca) (521.9 ± 1.8 mg/kg) and magnesium (Mg) (397.4 ± 1.3 mg/kg) were present in the plant. These high concentrations of calcium, iron and magnesium in this plant should be useful for electrolyte balance, enhancement of growth, bone and teeth formation, and activation of enzyme reactions. It should a...","internal_url":"https://www.academia.edu/65217120/Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria","translated_internal_url":"","created_at":"2021-12-20T12:52:20.294-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="9206678"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/9206678/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls_CYP2C19_genotypes_in_Nigerian_population"><img alt="Research paper thumbnail of Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population" class="work-thumbnail" src="https://attachments.academia-assets.com/47851341/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/9206678/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls_CYP2C19_genotypes_in_Nigerian_population">Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://pgschoolui.academia.edu/ChinedumBabalola">Chinedum P E A C E Babalola</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://oou.academia.edu/olufunmilayoadejumo">olufunmilayo adejumo</a></span></div><div class="wp-workCard_item"><span>Journal of Clinical Pharmacy and Therapeutics</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a pro-drug used for malaria prophylaxis differently and the frequency of the different alleles may be different in patients with sickle-cell disease (SCD) and normal controls. The objective of this study was to evaluate CYP2C19 *1, *2 and *3 allele and genotype frequencies in Nigerian normal controls and SCD patients, and to further compare variant CYP2C19 frequencies in Nigerians with other African populations.Methods: Genotyping was carried out with PCR and restriction fragment length polymorphism analysis.Results and discussion: CYP2C19 *1 (84·3 vs. 84·9%) or *2 allele frequency (15·7 vs. 15·1%) was not significantly different between patients with SCD and normal subjects. No *3 allele was detected in the cohort. The SCD group exhibited a statistically significantly lower frequency of *1/*1 genotype (69·6%) compared with normal controls (74·4%). Frequency of *2/*2 was significantly lower in SCD (0·9%) compared with normal controls (4·7%). Frequencies of *1/*2 (29·6 vs. 20·9%) were no different in SCD and normal controls.Conclusion: Prevalence of CYP2C19 polymorphisms was defined for the first time in Nigerian normal and SCD populations. Nigerian SCD patients exhibited significantly lower CYP2C19 *1/*1 and *2/*2 frequencies than normal controls. No differences were detected in CYP2C19 allele or genotype frequencies in normal subjects between this study and previous reports in other African populations.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="79704beb30e4abc5a9ef642a49c67d78" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":47851341,"asset_id":9206678,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/47851341/download_file?st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="9206678"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="9206678"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 9206678; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=9206678]").text(description); $(".js-view-count[data-work-id=9206678]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 9206678; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='9206678']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 9206678, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "79704beb30e4abc5a9ef642a49c67d78" } } $('.js-work-strip[data-work-id=9206678]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":9206678,"title":"Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population","translated_title":"","metadata":{"abstract":"Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a pro-drug used for malaria prophylaxis differently and the frequency of the different alleles may be different in patients with sickle-cell disease (SCD) and normal controls. The objective of this study was to evaluate CYP2C19 *1, *2 and *3 allele and genotype frequencies in Nigerian normal controls and SCD patients, and to further compare variant CYP2C19 frequencies in Nigerians with other African populations.Methods: Genotyping was carried out with PCR and restriction fragment length polymorphism analysis.Results and discussion: CYP2C19 *1 (84·3 vs. 84·9%) or *2 allele frequency (15·7 vs. 15·1%) was not significantly different between patients with SCD and normal subjects. No *3 allele was detected in the cohort. The SCD group exhibited a statistically significantly lower frequency of *1/*1 genotype (69·6%) compared with normal controls (74·4%). Frequency of *2/*2 was significantly lower in SCD (0·9%) compared with normal controls (4·7%). Frequencies of *1/*2 (29·6 vs. 20·9%) were no different in SCD and normal controls.Conclusion: Prevalence of CYP2C19 polymorphisms was defined for the first time in Nigerian normal and SCD populations. Nigerian SCD patients exhibited significantly lower CYP2C19 *1/*1 and *2/*2 frequencies than normal controls. No differences were detected in CYP2C19 allele or genotype frequencies in normal subjects between this study and previous reports in other African populations.","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"Journal of Clinical Pharmacy and Therapeutics"},"translated_abstract":"Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a pro-drug used for malaria prophylaxis differently and the frequency of the different alleles may be different in patients with sickle-cell disease (SCD) and normal controls. The objective of this study was to evaluate CYP2C19 *1, *2 and *3 allele and genotype frequencies in Nigerian normal controls and SCD patients, and to further compare variant CYP2C19 frequencies in Nigerians with other African populations.Methods: Genotyping was carried out with PCR and restriction fragment length polymorphism analysis.Results and discussion: CYP2C19 *1 (84·3 vs. 84·9%) or *2 allele frequency (15·7 vs. 15·1%) was not significantly different between patients with SCD and normal subjects. No *3 allele was detected in the cohort. The SCD group exhibited a statistically significantly lower frequency of *1/*1 genotype (69·6%) compared with normal controls (74·4%). Frequency of *2/*2 was significantly lower in SCD (0·9%) compared with normal controls (4·7%). Frequencies of *1/*2 (29·6 vs. 20·9%) were no different in SCD and normal controls.Conclusion: Prevalence of CYP2C19 polymorphisms was defined for the first time in Nigerian normal and SCD populations. Nigerian SCD patients exhibited significantly lower CYP2C19 *1/*1 and *2/*2 frequencies than normal controls. No differences were detected in CYP2C19 allele or genotype frequencies in normal subjects between this study and previous reports in other African populations.","internal_url":"https://www.academia.edu/9206678/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls_CYP2C19_genotypes_in_Nigerian_population","translated_internal_url":"","created_at":"2014-11-09T09:19:20.980-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":21090018,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":33255924,"work_id":9206678,"tagging_user_id":21090018,"tagged_user_id":null,"co_author_invite_id":1502807,"email":"s***r@temple.edu","display_order":0,"name":"Swati Nagar","title":"Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population"},{"id":33255925,"work_id":9206678,"tagging_user_id":21090018,"tagged_user_id":2660325,"co_author_invite_id":null,"email":"f***o@yahoo.co.uk","affiliation":"Olabisi Onabanjo University","display_order":4194304,"name":"olufunmilayo adejumo","title":"Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian 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href="https://www.academia.edu/54031439/Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry"><img alt="Research paper thumbnail of Elevated Iron Levels in Machine-Grinded Cassava (Manihot esculenta, Euphorbiaceae) in Iwo, Southwest Nigeria as Determined by Atomic Absorption Spectrometry" class="work-thumbnail" src="https://attachments.academia-assets.com/70591958/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/54031439/Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry">Elevated Iron Levels in Machine-Grinded Cassava (Manihot esculenta, Euphorbiaceae) in Iwo, Southwest Nigeria as Determined by Atomic Absorption Spectrometry</a></div><div class="wp-workCard_item"><span>Journal of Food Studies</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The potential of trace amounts of elements to contaminate food during processing in some local co...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The potential of trace amounts of elements to contaminate food during processing in some local communities of Nigeria has since been a subject of concern. In Iwo, South West Nigeria, the processing method of converting the highly perishable cassava tubers to more stable products such as the roasted granular product, Gari involves grating/grinding of peeled cassava tubers and this process is suspected to introduce trace elements into the final product. This study determined and compared the levels of trace elements in peeled and machine-grinded cassava tuber samples. Peeled cassava tuber samples and machine-grinded cassava tuber samples were collected, prepared by acid digestion and filtration. Elemental analysis was carried out using PG-990 Atomic Absorption Spectrophotometer in the flame configuration mode. Iron (9.500 ± 0.025 mg/kg), Copper (11.200 ± 0.025 mg/kg) and Magnesium (251.317 ± 0.038 mg/kg) were present in the peeled cassava tubers; while for the machine-grinded cassava ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b50a9f7b26a099be41e29ecff1784bb5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":70591958,"asset_id":54031439,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/70591958/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="54031439"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="54031439"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 54031439; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=54031439]").text(description); $(".js-view-count[data-work-id=54031439]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 54031439; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='54031439']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 54031439, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b50a9f7b26a099be41e29ecff1784bb5" } } $('.js-work-strip[data-work-id=54031439]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":54031439,"title":"Elevated Iron Levels in Machine-Grinded Cassava (Manihot esculenta, Euphorbiaceae) in Iwo, Southwest Nigeria as Determined by Atomic Absorption Spectrometry","translated_title":"","metadata":{"abstract":"The potential of trace amounts of elements to contaminate food during processing in some local communities of Nigeria has since been a subject of concern. In Iwo, South West Nigeria, the processing method of converting the highly perishable cassava tubers to more stable products such as the roasted granular product, Gari involves grating/grinding of peeled cassava tubers and this process is suspected to introduce trace elements into the final product. This study determined and compared the levels of trace elements in peeled and machine-grinded cassava tuber samples. Peeled cassava tuber samples and machine-grinded cassava tuber samples were collected, prepared by acid digestion and filtration. Elemental analysis was carried out using PG-990 Atomic Absorption Spectrophotometer in the flame configuration mode. Iron (9.500 ± 0.025 mg/kg), Copper (11.200 ± 0.025 mg/kg) and Magnesium (251.317 ± 0.038 mg/kg) were present in the peeled cassava tubers; while for the machine-grinded cassava ...","publisher":"Macrothink Institute, Inc.","publication_name":"Journal of Food Studies"},"translated_abstract":"The potential of trace amounts of elements to contaminate food during processing in some local communities of Nigeria has since been a subject of concern. In Iwo, South West Nigeria, the processing method of converting the highly perishable cassava tubers to more stable products such as the roasted granular product, Gari involves grating/grinding of peeled cassava tubers and this process is suspected to introduce trace elements into the final product. This study determined and compared the levels of trace elements in peeled and machine-grinded cassava tuber samples. Peeled cassava tuber samples and machine-grinded cassava tuber samples were collected, prepared by acid digestion and filtration. Elemental analysis was carried out using PG-990 Atomic Absorption Spectrophotometer in the flame configuration mode. Iron (9.500 ± 0.025 mg/kg), Copper (11.200 ± 0.025 mg/kg) and Magnesium (251.317 ± 0.038 mg/kg) were present in the peeled cassava tubers; while for the machine-grinded cassava ...","internal_url":"https://www.academia.edu/54031439/Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry","translated_internal_url":"","created_at":"2021-09-29T13:16:14.699-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":70591958,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/70591958/thumbnails/1.jpg","file_name":"12315.pdf","download_url":"https://www.academia.edu/attachments/70591958/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Elevated_Iron_Levels_in_Machine_Grinded.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/70591958/12315-libre.pdf?1632950216=\u0026response-content-disposition=attachment%3B+filename%3DElevated_Iron_Levels_in_Machine_Grinded.pdf\u0026Expires=1732460265\u0026Signature=R~Q4UiREoQcRt2KuVlK3esQbpFqBi9QBiDv8EQp12QIvWZtLA~zQZKyWS8fWGj8p-Dzua2nnCuc9X1IQaBdFm7Yup8RQAe2D3aJ4aGCi0feaF0naa4kS7SpfPZtaY5QNIkYQ4cJ3Wq6yOK1fpnQZYGBbP6n7DtwqrJDZ~A1Uw4ni9tghHh6PSHI8pwvmnDltw7TSaZ1HOluqLnvCQN7jIaNrgKsSRnJzuKq1VLZpFawV1l9JSwGOqb0g2vbrhHfZ5k9hP99P8UWDL6F5STrmO3WCvrc1Wue59MS3BTxaObSHW3JnJu5w4y9D4os36CGP1AultfQosx6dVorYfJ0~aA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry","translated_slug":"","page_count":8,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[{"id":70591958,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/70591958/thumbnails/1.jpg","file_name":"12315.pdf","download_url":"https://www.academia.edu/attachments/70591958/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Elevated_Iron_Levels_in_Machine_Grinded.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/70591958/12315-libre.pdf?1632950216=\u0026response-content-disposition=attachment%3B+filename%3DElevated_Iron_Levels_in_Machine_Grinded.pdf\u0026Expires=1732460265\u0026Signature=R~Q4UiREoQcRt2KuVlK3esQbpFqBi9QBiDv8EQp12QIvWZtLA~zQZKyWS8fWGj8p-Dzua2nnCuc9X1IQaBdFm7Yup8RQAe2D3aJ4aGCi0feaF0naa4kS7SpfPZtaY5QNIkYQ4cJ3Wq6yOK1fpnQZYGBbP6n7DtwqrJDZ~A1Uw4ni9tghHh6PSHI8pwvmnDltw7TSaZ1HOluqLnvCQN7jIaNrgKsSRnJzuKq1VLZpFawV1l9JSwGOqb0g2vbrhHfZ5k9hP99P8UWDL6F5STrmO3WCvrc1Wue59MS3BTxaObSHW3JnJu5w4y9D4os36CGP1AultfQosx6dVorYfJ0~aA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":43678,"name":"Food Studies","url":"https://www.academia.edu/Documents/in/Food_Studies"}],"urls":[{"id":11719785,"url":"http://www.macrothink.org/journal/index.php/jfs/article/viewFile/15287/12315"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="54031424"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/54031424/Physicochemical_Characteristics_and_HPLC_Determination_of_Alpha_Tocopherol_in_Eighteen_Edible_Vegetable_Oils_Marketed_in_Nigeria"><img alt="Research paper thumbnail of Physicochemical Characteristics and HPLC Determination of Alpha-Tocopherol in Eighteen Edible Vegetable Oils Marketed in Nigeria" class="work-thumbnail" src="https://attachments.academia-assets.com/70591840/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/54031424/Physicochemical_Characteristics_and_HPLC_Determination_of_Alpha_Tocopherol_in_Eighteen_Edible_Vegetable_Oils_Marketed_in_Nigeria">Physicochemical Characteristics and HPLC Determination of Alpha-Tocopherol in Eighteen Edible Vegetable Oils Marketed in Nigeria</a></div><div class="wp-workCard_item"><span>Dhaka University Journal of Pharmaceutical Sciences</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Eighteen brands of vegetable oils available in the local market were extracted with n-hexane befo...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Eighteen brands of vegetable oils available in the local market were extracted with n-hexane before analysis for alpha-tocopherol by RP-HPLC method. The chromatographic separation occurred isocratically with methanol-water [96:4%v/v] at 0.9 ml/min flow rate. Tocopheryl acetate was the internal standard and alpha-tocopherol was eluted at 7.87 min. Free fatty acids value [FFAVs], peroxide value [PV], iodine value [IV] and saponification values [SV] were determined as quality parameters. Calibration curve was linear [r2 0.9969] and the method was precise with relative standard deviation of 0.35% and mean recovery, 87.39%. Alpha-tocopherol concentration ranged from 0-9.22 mg/100g with the highest in Tropical sunflower oil [9.22 mg/100g] and the lowest [1.16 mg/100g] in Laziz oil. Alpha-tocopherol was not detected in unbranded, local palm oil. The calculated percentage daily value [% DV] of vitamin E ranged from 0- 8.60%. Significant difference [p&lt;0.05] between % DV and recommended di...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="263ae15da710fc98385b96b4dfea3659" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":70591840,"asset_id":54031424,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/70591840/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="54031424"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="54031424"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 54031424; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=54031424]").text(description); $(".js-view-count[data-work-id=54031424]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 54031424; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='54031424']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 54031424, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "263ae15da710fc98385b96b4dfea3659" } } $('.js-work-strip[data-work-id=54031424]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":54031424,"title":"Physicochemical Characteristics and HPLC Determination of Alpha-Tocopherol in Eighteen Edible Vegetable Oils Marketed in Nigeria","translated_title":"","metadata":{"abstract":"Eighteen brands of vegetable oils available in the local market were extracted with n-hexane before analysis for alpha-tocopherol by RP-HPLC method. The chromatographic separation occurred isocratically with methanol-water [96:4%v/v] at 0.9 ml/min flow rate. Tocopheryl acetate was the internal standard and alpha-tocopherol was eluted at 7.87 min. Free fatty acids value [FFAVs], peroxide value [PV], iodine value [IV] and saponification values [SV] were determined as quality parameters. Calibration curve was linear [r2 0.9969] and the method was precise with relative standard deviation of 0.35% and mean recovery, 87.39%. Alpha-tocopherol concentration ranged from 0-9.22 mg/100g with the highest in Tropical sunflower oil [9.22 mg/100g] and the lowest [1.16 mg/100g] in Laziz oil. Alpha-tocopherol was not detected in unbranded, local palm oil. The calculated percentage daily value [% DV] of vitamin E ranged from 0- 8.60%. Significant difference [p\u0026lt;0.05] between % DV and recommended di...","publisher":"Bangladesh Journals Online (JOL)","publication_name":"Dhaka University Journal of Pharmaceutical Sciences"},"translated_abstract":"Eighteen brands of vegetable oils available in the local market were extracted with n-hexane before analysis for alpha-tocopherol by RP-HPLC method. The chromatographic separation occurred isocratically with methanol-water [96:4%v/v] at 0.9 ml/min flow rate. Tocopheryl acetate was the internal standard and alpha-tocopherol was eluted at 7.87 min. Free fatty acids value [FFAVs], peroxide value [PV], iodine value [IV] and saponification values [SV] were determined as quality parameters. Calibration curve was linear [r2 0.9969] and the method was precise with relative standard deviation of 0.35% and mean recovery, 87.39%. Alpha-tocopherol concentration ranged from 0-9.22 mg/100g with the highest in Tropical sunflower oil [9.22 mg/100g] and the lowest [1.16 mg/100g] in Laziz oil. Alpha-tocopherol was not detected in unbranded, local palm oil. The calculated percentage daily value [% DV] of vitamin E ranged from 0- 8.60%. Significant difference [p\u0026lt;0.05] between % DV and recommended di...","internal_url":"https://www.academia.edu/54031424/Physicochemical_Characteristics_and_HPLC_Determination_of_Alpha_Tocopherol_in_Eighteen_Edible_Vegetable_Oils_Marketed_in_Nigeria","translated_internal_url":"","created_at":"2021-09-29T13:15:55.957-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":70591840,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/70591840/thumbnails/1.jpg","file_name":"37905.pdf","download_url":"https://www.academia.edu/attachments/70591840/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Physicochemical_Characteristics_and_HPLC.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/70591840/37905-libre.pdf?1632950220=\u0026response-content-disposition=attachment%3B+filename%3DPhysicochemical_Characteristics_and_HPLC.pdf\u0026Expires=1732460266\u0026Signature=Vns3egk6TdU7PqWdXGQu1mcembxDwEebbcHnbFROLGTStdbrI8Rr~wAEgDz8ySZf3rWNDjTBfwMrcAE0K9nVkMsfFZQY5ZVuM~Gk3HOlY1rLpefolzkIS8RSwGDGxw~4nfAjSZ1hhTPmPwfpQFELeRHC6a-ElF2aLvoSo3HE9n3rxRYDOwCBzRHuV4iQtvNWuUvSEz3V-AClynELBsPfOkHtYqBt50Xcpqi-H8vBqmjjh0GhynAKKRsPvWCCIjEAJIctn7EFHeiKc4QPrFxY8XvEuMV3fhSbbQKKSQ1vosCiklOIv24Q5bXxBDZKG0B2NSqr4YW6TEHKz5-~L12yEA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Physicochemical_Characteristics_and_HPLC_Determination_of_Alpha_Tocopherol_in_Eighteen_Edible_Vegetable_Oils_Marketed_in_Nigeria","translated_slug":"","page_count":9,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[{"id":70591840,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/70591840/thumbnails/1.jpg","file_name":"37905.pdf","download_url":"https://www.academia.edu/attachments/70591840/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Physicochemical_Characteristics_and_HPLC.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/70591840/37905-libre.pdf?1632950220=\u0026response-content-disposition=attachment%3B+filename%3DPhysicochemical_Characteristics_and_HPLC.pdf\u0026Expires=1732460266\u0026Signature=Vns3egk6TdU7PqWdXGQu1mcembxDwEebbcHnbFROLGTStdbrI8Rr~wAEgDz8ySZf3rWNDjTBfwMrcAE0K9nVkMsfFZQY5ZVuM~Gk3HOlY1rLpefolzkIS8RSwGDGxw~4nfAjSZ1hhTPmPwfpQFELeRHC6a-ElF2aLvoSo3HE9n3rxRYDOwCBzRHuV4iQtvNWuUvSEz3V-AClynELBsPfOkHtYqBt50Xcpqi-H8vBqmjjh0GhynAKKRsPvWCCIjEAJIctn7EFHeiKc4QPrFxY8XvEuMV3fhSbbQKKSQ1vosCiklOIv24Q5bXxBDZKG0B2NSqr4YW6TEHKz5-~L12yEA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":70591839,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/70591839/thumbnails/1.jpg","file_name":"37905.pdf","download_url":"https://www.academia.edu/attachments/70591839/download_file","bulk_download_file_name":"Physicochemical_Characteristics_and_HPLC.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/70591839/37905-libre.pdf?1632950221=\u0026response-content-disposition=attachment%3B+filename%3DPhysicochemical_Characteristics_and_HPLC.pdf\u0026Expires=1732460266\u0026Signature=YlSvM66cCjEo~1OMdkIHdNkQ0hl9EF8PPB16XRFBsG~wEcm-dkCnzQDkVIeD3gq1HhBW1OzJq~3JqHmwvmYZUsc3BhZuqxpkqsXmKcklhKgQV8SqKLaSHwUebLH9KEvmJWkEJC50~JZ7t0HiCs5rCsZY5KYMbjtNJeyu9yWQCNgNfaQmEKgn59h2-dPWmgrYIXK7gjF5mej1sSMIKd4-PS8f4ESL1NzPO52KpTD8Wm3Bgzwie~zZY-1YN5Or1UP1yR8jpHBF1xtPImYdZdBNuxffb75yT43HWctpNjItPPU25FpXGFnyHfGg67huoZq80cjxoGILTFk6FLMYygdWnw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[],"urls":[{"id":11719779,"url":"https://www.banglajol.info/index.php/JPharma/article/download/54032/37905"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29753789"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29753789/Moringa_oleifera_Lam_Moringaceae_grown_in_Nigeria_In_vitro_antisickling_activity_on_deoxygenated_erythrocyte_cells"><img alt="Research paper thumbnail of Moringa oleifera Lam. (Moringaceae) grown in Nigeria: In vitro antisickling activity on deoxygenated erythrocyte cells" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29753789/Moringa_oleifera_Lam_Moringaceae_grown_in_Nigeria_In_vitro_antisickling_activity_on_deoxygenated_erythrocyte_cells">Moringa oleifera Lam. (Moringaceae) grown in Nigeria: In vitro antisickling activity on deoxygenated erythrocyte cells</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy and Bioallied Sciences</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Traditional medicine, which is more available and affordable for the poor uses medicinal plants f...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Traditional medicine, which is more available and affordable for the poor uses medicinal plants for the treatment and management of various ailments, including the sickle cell disease (SCD). About 24 million Nigerians are carriers of this sickled cell gene, while approximately 2.4 million are SCD patients. Moringa oleifera Lam. (Moringaceae) possesses high nutritional value and has been used in folklore medicine to treat various ailments related to pain and inflammation. Chemical, pharmacological and pharmacognostical applications of Moringa oleifera have been reported.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29753789"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29753789"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29753789; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29753789]").text(description); $(".js-view-count[data-work-id=29753789]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29753789; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29753789']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29753789, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=29753789]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29753789,"title":"Moringa oleifera Lam. (Moringaceae) grown in Nigeria: In vitro antisickling activity on deoxygenated erythrocyte cells","translated_title":"","metadata":{"abstract":"Traditional medicine, which is more available and affordable for the poor uses medicinal plants for the treatment and management of various ailments, including the sickle cell disease (SCD). About 24 million Nigerians are carriers of this sickled cell gene, while approximately 2.4 million are SCD patients. Moringa oleifera Lam. (Moringaceae) possesses high nutritional value and has been used in folklore medicine to treat various ailments related to pain and inflammation. Chemical, pharmacological and pharmacognostical applications of Moringa oleifera have been reported.","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Journal of Pharmacy and Bioallied Sciences"},"translated_abstract":"Traditional medicine, which is more available and affordable for the poor uses medicinal plants for the treatment and management of various ailments, including the sickle cell disease (SCD). About 24 million Nigerians are carriers of this sickled cell gene, while approximately 2.4 million are SCD patients. Moringa oleifera Lam. (Moringaceae) possesses high nutritional value and has been used in folklore medicine to treat various ailments related to pain and inflammation. Chemical, pharmacological and pharmacognostical applications of Moringa oleifera have been reported.","internal_url":"https://www.academia.edu/29753789/Moringa_oleifera_Lam_Moringaceae_grown_in_Nigeria_In_vitro_antisickling_activity_on_deoxygenated_erythrocyte_cells","translated_internal_url":"","created_at":"2016-11-09T07:08:45.001-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Moringa_oleifera_Lam_Moringaceae_grown_in_Nigeria_In_vitro_antisickling_activity_on_deoxygenated_erythrocyte_cells","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); 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Nigeria","display_order":4194304,"name":"Chinedum P E A C E Babalola","title":"Cytochrome P450 CYP2C19 Genotypes in Sickle Cell Disease Patients and Normal Controls in an African Population"},{"id":25822935,"work_id":29753785,"tagging_user_id":2660325,"tagged_user_id":null,"co_author_invite_id":1764503,"email":"t***a@post.com","display_order":6291456,"name":"Taiwo Kotila","title":"Cytochrome P450 CYP2C19 Genotypes in Sickle Cell Disease Patients and Normal Controls in an African Population"}],"downloadable_attachments":[],"slug":"Cytochrome_P450_CYP2C19_Genotypes_in_Sickle_Cell_Disease_Patients_and_Normal_Controls_in_an_African_Population","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29753784"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29753784/Antisickling_activities_of_extracts_of_leaf_seed_and_seed_pod_of_Garcinia_kola_Heckel"><img alt="Research paper thumbnail of Antisickling activities of extracts of leaf, seed and seed pod of Garcinia kola Heckel" class="work-thumbnail" src="https://attachments.academia-assets.com/50209549/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29753784/Antisickling_activities_of_extracts_of_leaf_seed_and_seed_pod_of_Garcinia_kola_Heckel">Antisickling activities of extracts of leaf, seed and seed pod of Garcinia kola Heckel</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://oou.academia.edu/olufunmilayoadejumo">olufunmilayo adejumo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://oouagoiwoye.academia.edu/PhilipOlatunji">Philip Olatunji</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Garcinia kola has been hitherto speculated as effective in the management of sickle cell disease ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Garcinia kola has been hitherto speculated as effective in the management of sickle cell disease (SCD). Investigations into the antisickling activities of both crude methanol extracts and the aqueous fractions of the leaf, seed and seed pod of G. kola were carried out using p-hydroxybenzoic acid and normal saline as positive and negative controls respectively. At the tested concentrations of 10.0, 1.0 and 0.1 mg/ml, the leaf extracts exhibited greatest antisickling activity whilst the seed pod had the least antisickling activity. However, it was observed that the activity of methanol extract of the seed pod did not differ significantly (p&gt;0.05) from that of the positive control, p-hydroxybenzoic acid. Results for screened phytochemicals of the investigated parts revealed the presence of saponins, tannins, combined and free anthraquinones. The results infer a preliminary confirmation for the effectiveness and use of Garcinia kola in the management of SCD and its implication in dru...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3465f6ec949e445fc8a1d98754b39df2" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":50209549,"asset_id":29753784,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/50209549/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29753784"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29753784"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29753784; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29753784]").text(description); $(".js-view-count[data-work-id=29753784]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29753784; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29753784']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29753784, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3465f6ec949e445fc8a1d98754b39df2" } } $('.js-work-strip[data-work-id=29753784]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29753784,"title":"Antisickling activities of extracts of leaf, seed and seed pod of Garcinia kola Heckel","translated_title":"","metadata":{"abstract":"Garcinia kola has been hitherto speculated as effective in the management of sickle cell disease (SCD). Investigations into the antisickling activities of both crude methanol extracts and the aqueous fractions of the leaf, seed and seed pod of G. kola were carried out using p-hydroxybenzoic acid and normal saline as positive and negative controls respectively. At the tested concentrations of 10.0, 1.0 and 0.1 mg/ml, the leaf extracts exhibited greatest antisickling activity whilst the seed pod had the least antisickling activity. However, it was observed that the activity of methanol extract of the seed pod did not differ significantly (p\u0026gt;0.05) from that of the positive control, p-hydroxybenzoic acid. Results for screened phytochemicals of the investigated parts revealed the presence of saponins, tannins, combined and free anthraquinones. The results infer a preliminary confirmation for the effectiveness and use of Garcinia kola in the management of SCD and its implication in dru..."},"translated_abstract":"Garcinia kola has been hitherto speculated as effective in the management of sickle cell disease (SCD). Investigations into the antisickling activities of both crude methanol extracts and the aqueous fractions of the leaf, seed and seed pod of G. kola were carried out using p-hydroxybenzoic acid and normal saline as positive and negative controls respectively. At the tested concentrations of 10.0, 1.0 and 0.1 mg/ml, the leaf extracts exhibited greatest antisickling activity whilst the seed pod had the least antisickling activity. However, it was observed that the activity of methanol extract of the seed pod did not differ significantly (p\u0026gt;0.05) from that of the positive control, p-hydroxybenzoic acid. Results for screened phytochemicals of the investigated parts revealed the presence of saponins, tannins, combined and free anthraquinones. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="29753783"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/29753783/In_vitro_antisickling_activities_and_phytochemical_evaluation_of_Plumbago_zeylanica_and_Uvaria_chamae"><img alt="Research paper thumbnail of In vitro antisickling activities and phytochemical evaluation of Plumbago zeylanica and Uvaria chamae" class="work-thumbnail" src="https://attachments.academia-assets.com/50209550/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29753783/In_vitro_antisickling_activities_and_phytochemical_evaluation_of_Plumbago_zeylanica_and_Uvaria_chamae">In vitro antisickling activities and phytochemical evaluation of Plumbago zeylanica and Uvaria chamae</a></div><div class="wp-workCard_item"><span>African Journal of …</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="1d416660aed98d30157ae217f6703d57" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":50209550,"asset_id":29753783,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/50209550/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29753783"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29753783"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29753783; 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Using both crude methanol extract and its aqueous fraction, in vitro antisickling activities of these plant parts were evaluated using p-hydroxybenzoic acid and normal saline as positive and negative controls, respectively. Phytochemical screening of the investigated plant specimens revealed the presence of flavonoids, saponnins, alkaloids, tannins, cardiac glycosides free and combined anthraquinones. Extracts/fractions of P. zeylanica had a significantly higher (p \u003c 0.05) antisickling activity at the tested concentrations of 10.0, 1.0 and 0.1 mg/ml. Therefore, the use of these plants by the traditional medical practitioners in the treatment of SCD in Ogun State, Nigeria is justified. The implication of these results is in defining the role of each plant specimen in traditional recipes for SCD management and drug development is presented.","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"African Journal of …","grobid_abstract_attachment_id":50209550},"translated_abstract":null,"internal_url":"https://www.academia.edu/29753783/In_vitro_antisickling_activities_and_phytochemical_evaluation_of_Plumbago_zeylanica_and_Uvaria_chamae","translated_internal_url":"","created_at":"2016-11-09T07:08:27.361-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":25978420,"work_id":29753783,"tagging_user_id":2660325,"tagged_user_id":143140,"co_author_invite_id":null,"email":"a***o@yahoo.com","affiliation":"The Polytechnic, Ibadan","display_order":0,"name":"Adelodun Kolapo","title":"In vitro antisickling activities and phytochemical evaluation of Plumbago zeylanica and Uvaria chamae"},{"id":25978421,"work_id":29753783,"tagging_user_id":2660325,"tagged_user_id":44027255,"co_author_invite_id":null,"email":"k***s@yahoo.co.uk","display_order":4194304,"name":"Lateef Kasim","title":"In vitro antisickling activities and phytochemical evaluation of Plumbago zeylanica and Uvaria chamae"}],"downloadable_attachments":[{"id":50209550,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/50209550/thumbnails/1.jpg","file_name":"In_vitro_antisickling_activities_and_phy20161109-6594-1d0tk2u.pdf","download_url":"https://www.academia.edu/attachments/50209550/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"In_vitro_antisickling_activities_and_phy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/50209550/In_vitro_antisickling_activities_and_phy20161109-6594-1d0tk2u-libre.pdf?1478706352=\u0026response-content-disposition=attachment%3B+filename%3DIn_vitro_antisickling_activities_and_phy.pdf\u0026Expires=1732460266\u0026Signature=ON29YDkrHZ748AvGm6QmsY0Xt7s7BK5wpGJzMGorkTw7blMyITikhWx3Hyr70h7Ulb0hC-~Oq-jYsukT9MjkUIW6G6yajKYHUb8ioW7YBg4GYcyLQYiJqvxcvCXlO7EubQPFsI0S--GczIQCqAPC1ErXYGEzAjM5eTI7jOgpHI2a5SiS166o-h6SBzufTIBMjZuv0DYjG78Ng2S91C7W3W7tjLI6oj~ZGZekzfRfJwKsUCX-OwcUhWf1cgzOaNzfT9J7agnirdXlReaGYd1vI1QcHyvesne~OnRzgaSfj5Q65~p44FbSmcfeXJNXREg24qxCPhNAPfeNWc6MVMfOFQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"In_vitro_antisickling_activities_and_phytochemical_evaluation_of_Plumbago_zeylanica_and_Uvaria_chamae","translated_slug":"","page_count":5,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[{"id":50209550,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/50209550/thumbnails/1.jpg","file_name":"In_vitro_antisickling_activities_and_phy20161109-6594-1d0tk2u.pdf","download_url":"https://www.academia.edu/attachments/50209550/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"In_vitro_antisickling_activities_and_phy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/50209550/In_vitro_antisickling_activities_and_phy20161109-6594-1d0tk2u-libre.pdf?1478706352=\u0026response-content-disposition=attachment%3B+filename%3DIn_vitro_antisickling_activities_and_phy.pdf\u0026Expires=1732460266\u0026Signature=ON29YDkrHZ748AvGm6QmsY0Xt7s7BK5wpGJzMGorkTw7blMyITikhWx3Hyr70h7Ulb0hC-~Oq-jYsukT9MjkUIW6G6yajKYHUb8ioW7YBg4GYcyLQYiJqvxcvCXlO7EubQPFsI0S--GczIQCqAPC1ErXYGEzAjM5eTI7jOgpHI2a5SiS166o-h6SBzufTIBMjZuv0DYjG78Ng2S91C7W3W7tjLI6oj~ZGZekzfRfJwKsUCX-OwcUhWf1cgzOaNzfT9J7agnirdXlReaGYd1vI1QcHyvesne~OnRzgaSfj5Q65~p44FbSmcfeXJNXREg24qxCPhNAPfeNWc6MVMfOFQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":90451,"name":"African","url":"https://www.academia.edu/Documents/in/African"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="6119577" id="papers"><div class="js-work-strip profile--work_container" data-work-id="100046847"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/100046847/Plasmid_DNA_mediated_vancomycin_resistant_Staphylococcus_aureus_VRSA_from_cases_of_urinary_tract_infection"><img alt="Research paper thumbnail of Plasmid DNA mediated vancomycin-resistant Staphylococcus aureus (VRSA) from cases of urinary tract infection" class="work-thumbnail" src="https://attachments.academia-assets.com/100975674/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/100046847/Plasmid_DNA_mediated_vancomycin_resistant_Staphylococcus_aureus_VRSA_from_cases_of_urinary_tract_infection">Plasmid DNA mediated vancomycin-resistant Staphylococcus aureus (VRSA) from cases of urinary tract infection</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Bioresources</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrin...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrinsic virulence. Sixty isolates of Staphylococcus aureus tested positive as vancomycin possessive isolates on Brain Heart Infusion Agar medium fortified with 6 μg/mL vancomycin from 100 clinical samples of urine from patients with cases of UTIs via agar diffusion method. Standard 30 μg vancomycin disc served as control. Increase in zones of growth inhibition in relation to vancomycin concentrations was noticed in some of the isolates while it was reversed in others, despite the increase in concentration. Typed strain was susceptible to six concentrations of vancomycin exposed and to the control. Thirty one of the sixty isolates were resistant to vancomycin control. Resistant isolates from standard vancomycin discs were then subjected to molecular investigation. Of the 31 isolates exposed to gel electrophoresis, 14 (47%)elicited plasmids of varied molecular weights ranging from 0.79-23.13 k...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="84f769f40848102896df17e01b89335c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":100975674,"asset_id":100046847,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/100975674/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="100046847"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="100046847"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 100046847; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=100046847]").text(description); $(".js-view-count[data-work-id=100046847]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 100046847; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='100046847']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 100046847, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "84f769f40848102896df17e01b89335c" } } $('.js-work-strip[data-work-id=100046847]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":100046847,"title":"Plasmid DNA mediated vancomycin-resistant Staphylococcus aureus (VRSA) from cases of urinary tract infection","translated_title":"","metadata":{"abstract":"Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrinsic virulence. 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Of the 31 isolates exposed to gel electrophoresis, 14 (47%)elicited plasmids of varied molecular weights ranging from 0.79-23.13 k...","publisher":"African Journals Online (AJOL)","publication_name":"Journal of Pharmacy \u0026amp; Bioresources"},"translated_abstract":"Vancomycin resistance commonly occurs with Staphylococcus aureus, a pathogen that exhibits intrinsic virulence. Sixty isolates of Staphylococcus aureus tested positive as vancomycin possessive isolates on Brain Heart Infusion Agar medium fortified with 6 μg/mL vancomycin from 100 clinical samples of urine from patients with cases of UTIs via agar diffusion method. Standard 30 μg vancomycin disc served as control. Increase in zones of growth inhibition in relation to vancomycin concentrations was noticed in some of the isolates while it was reversed in others, despite the increase in concentration. Typed strain was susceptible to six concentrations of vancomycin exposed and to the control. Thirty one of the sixty isolates were resistant to vancomycin control. Resistant isolates from standard vancomycin discs were then subjected to molecular investigation. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96013201"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96013201/Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria"><img alt="Research paper thumbnail of Bacteriological evaluation of instant noodles stored under sub-optimal conditions from selected markets in Sagamu- Ibafo axis of Ogun State, Nigeria" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96013201/Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria">Bacteriological evaluation of instant noodles stored under sub-optimal conditions from selected markets in Sagamu- Ibafo axis of Ogun State, Nigeria</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy &amp; Bioresources</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical s...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical status, and resistance of the isolates to conventional antibiotics, in addition to pH. These brands were cultured on plate count agar for bacterial enumeration while isolates were challenged on selective media for bacteria of clinical status. The antibiogram was determined using standard methods. The pH varied from acidic (4.92) as shown in GPJ 3 to closely neutral (6.94) as recorded in HWJ 2. TTJ1 had the lowest average bacteria count of 1.6 x 103 while BFJ5 with 6.3 x 105 counts was the highest. Prevalence of isolates of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa varied in the ratio 40:30:30. Of the 40 samples, 8 of the 16 Escherichia coli were resistant to gentamicin, ciprofloxacin, and Augmentin, 7 of the 12 Staphylococcus aureus elicited resistance to ampicillin and cotrimoxazole while 8 of the Pseudomonas aeruginosa were resistant to meropenem, cotrimoxazole...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96013201"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96013201"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96013201; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96013201]").text(description); $(".js-view-count[data-work-id=96013201]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96013201; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96013201']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96013201, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=96013201]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96013201,"title":"Bacteriological evaluation of instant noodles stored under sub-optimal conditions from selected markets in Sagamu- Ibafo axis of Ogun State, Nigeria","translated_title":"","metadata":{"abstract":"This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical status, and resistance of the isolates to conventional antibiotics, in addition to pH. These brands were cultured on plate count agar for bacterial enumeration while isolates were challenged on selective media for bacteria of clinical status. The antibiogram was determined using standard methods. The pH varied from acidic (4.92) as shown in GPJ 3 to closely neutral (6.94) as recorded in HWJ 2. TTJ1 had the lowest average bacteria count of 1.6 x 103 while BFJ5 with 6.3 x 105 counts was the highest. Prevalence of isolates of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa varied in the ratio 40:30:30. Of the 40 samples, 8 of the 16 Escherichia coli were resistant to gentamicin, ciprofloxacin, and Augmentin, 7 of the 12 Staphylococcus aureus elicited resistance to ampicillin and cotrimoxazole while 8 of the Pseudomonas aeruginosa were resistant to meropenem, cotrimoxazole...","publisher":"African Journals Online (AJOL)","publication_name":"Journal of Pharmacy \u0026amp; Bioresources"},"translated_abstract":"This study evaluated 8 brands of 5 packets each of instant noodles for bacterial load, clinical status, and resistance of the isolates to conventional antibiotics, in addition to pH. These brands were cultured on plate count agar for bacterial enumeration while isolates were challenged on selective media for bacteria of clinical status. The antibiogram was determined using standard methods. The pH varied from acidic (4.92) as shown in GPJ 3 to closely neutral (6.94) as recorded in HWJ 2. TTJ1 had the lowest average bacteria count of 1.6 x 103 while BFJ5 with 6.3 x 105 counts was the highest. Prevalence of isolates of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa varied in the ratio 40:30:30. Of the 40 samples, 8 of the 16 Escherichia coli were resistant to gentamicin, ciprofloxacin, and Augmentin, 7 of the 12 Staphylococcus aureus elicited resistance to ampicillin and cotrimoxazole while 8 of the Pseudomonas aeruginosa were resistant to meropenem, cotrimoxazole...","internal_url":"https://www.academia.edu/96013201/Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria","translated_internal_url":"","created_at":"2023-01-30T22:39:22.876-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Bacteriological_evaluation_of_instant_noodles_stored_under_sub_optimal_conditions_from_selected_markets_in_Sagamu_Ibafo_axis_of_Ogun_State_Nigeria","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[],"research_interests":[{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[{"id":28547082,"url":"https://www.ajol.info/index.php/jpb/article/download/238797/225684"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="96013176"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/96013176/Quality_Characteristics_and_%CE%91lpha_Tocopherol_Content_of_Shea_Butter_Samples_from_Selected_Markets_Within_Three_Southwestern_States_of_Nigeria"><img alt="Research paper thumbnail of Quality Characteristics and Αlpha-Tocopherol Content of Shea Butter Samples from Selected Markets Within Three Southwestern States of Nigeria" class="work-thumbnail" src="https://attachments.academia-assets.com/98031285/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/96013176/Quality_Characteristics_and_%CE%91lpha_Tocopherol_Content_of_Shea_Butter_Samples_from_Selected_Markets_Within_Three_Southwestern_States_of_Nigeria">Quality Characteristics and Αlpha-Tocopherol Content of Shea Butter Samples from Selected Markets Within Three Southwestern States of Nigeria</a></div><div class="wp-workCard_item"><span>Dhaka University Journal of Pharmaceutical Sciences</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC quality characteristics and α-tocopherol content. The α-tocopherol was determined by RP-HPLC and mg per serving and % daily values (% DV) were estimated. The ranges of acid value (AV) [mgKOH/kg], free fatty acid (FFA) [%], peroxide value (PV) [meqO2/Kg], iodine value (IV) [gI2/100g] and saponification value (SV) [mgKOH/g] were 2.20- 2.59, 1.15-1.30, 0.75-0.95, 44.43-47.85 and 170.08-259.30, respectively. The -tocopherol had a retention time of 3.561 minutes and its content ranged from 1.15-2.60 mg/100 g in the samples, but 5.25 mg/100 g for the laboratory sample. Milligram (mg) per serving and percentage dietary value were 0.16-0.74 and 1.07-4.93, respectively. Quality characteristics varied significantly (p &lt; 0.05) both within and across different markets. Based on the PV and IV results, the marketed shea butter samples may be both food and industry-grade but failed the FFA test. S...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="136405377a7f9fd5bd85ff69677e37e7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98031285,"asset_id":96013176,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98031285/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="96013176"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="96013176"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 96013176; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=96013176]").text(description); $(".js-view-count[data-work-id=96013176]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 96013176; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='96013176']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 96013176, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "136405377a7f9fd5bd85ff69677e37e7" } } $('.js-work-strip[data-work-id=96013176]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":96013176,"title":"Quality Characteristics and Αlpha-Tocopherol Content of Shea Butter Samples from Selected Markets Within Three Southwestern States of Nigeria","translated_title":"","metadata":{"abstract":"Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC quality characteristics and α-tocopherol content. The α-tocopherol was determined by RP-HPLC and mg per serving and % daily values (% DV) were estimated. The ranges of acid value (AV) [mgKOH/kg], free fatty acid (FFA) [%], peroxide value (PV) [meqO2/Kg], iodine value (IV) [gI2/100g] and saponification value (SV) [mgKOH/g] were 2.20- 2.59, 1.15-1.30, 0.75-0.95, 44.43-47.85 and 170.08-259.30, respectively. The -tocopherol had a retention time of 3.561 minutes and its content ranged from 1.15-2.60 mg/100 g in the samples, but 5.25 mg/100 g for the laboratory sample. Milligram (mg) per serving and percentage dietary value were 0.16-0.74 and 1.07-4.93, respectively. Quality characteristics varied significantly (p \u0026lt; 0.05) both within and across different markets. Based on the PV and IV results, the marketed shea butter samples may be both food and industry-grade but failed the FFA test. S...","publisher":"Bangladesh Journals Online (JOL)","publication_name":"Dhaka University Journal of Pharmaceutical Sciences"},"translated_abstract":"Shea (Vitellaria paradoxa) butter samples from selected markets in Nigeria were analyzed for AOAC quality characteristics and α-tocopherol content. The α-tocopherol was determined by RP-HPLC and mg per serving and % daily values (% DV) were estimated. The ranges of acid value (AV) [mgKOH/kg], free fatty acid (FFA) [%], peroxide value (PV) [meqO2/Kg], iodine value (IV) [gI2/100g] and saponification value (SV) [mgKOH/g] were 2.20- 2.59, 1.15-1.30, 0.75-0.95, 44.43-47.85 and 170.08-259.30, respectively. The -tocopherol had a retention time of 3.561 minutes and its content ranged from 1.15-2.60 mg/100 g in the samples, but 5.25 mg/100 g for the laboratory sample. Milligram (mg) per serving and percentage dietary value were 0.16-0.74 and 1.07-4.93, respectively. Quality characteristics varied significantly (p \u0026lt; 0.05) both within and across different markets. Based on the PV and IV results, the marketed shea butter samples may be both food and industry-grade but failed the FFA test. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="77856671"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/77856671/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls"><img alt="Research paper thumbnail of Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls" class="work-thumbnail" src="https://attachments.academia-assets.com/85104754/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/77856671/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls">Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls</a></div><div class="wp-workCard_item"><span>Journal of Clinical Pharmacy and Therapeutics</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="48bce6cd091db48e97638bb1707d52bc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":85104754,"asset_id":77856671,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/85104754/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="77856671"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="77856671"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 77856671; 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/></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/70966689/Phytochemistry_and_In_vitro_Antimicrobial_Activity_of_Five_Plant_Species_against_Nine_Common_Human_Pathogens">Phytochemistry and In vitro Antimicrobial Activity of Five Plant Species against Nine Common Human Pathogens</a></div><div class="wp-workCard_item"><span>Dhaka University Journal of Pharmaceutical Sciences</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Momordica charantia, Senna podocarpa, Senna alata, Ocimum gratissimum, and Sida acuta which have ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Momordica charantia, Senna podocarpa, Senna alata, Ocimum gratissimum, and Sida acuta which have reportedly been used in folklore for the treatment of various diseases were studied for their antimicrobial activity. Crude methanolic extracts of the leaves were screened for phytochemicals after which they were tested in vitro for activity against clinical isolates of Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa, Proteus vulgaris, Bacillus subtilis, Enterobacter aerogenes, Aspergillus niger, A, flavus and Candida albicans. Phytochemicals present in the extracts included saponins, alkaloids, anthraquinones, tannins, flavonoids and cardiac glycosides. These extracts also showed varying degrees of activity against tested organisms at a concentration range of 15.6 to 500 mg/ml. However, S. acuta showed activity against P. vulgaris, E. aerogenes and As. flavus only. The MIC of the extracts against test organisms ranged from 31.25 to 250 mg/ml. The significant antimicrob...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="be282564bd44b870871117474e7259e1" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":80500178,"asset_id":70966689,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/80500178/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="70966689"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="70966689"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 70966689; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=70966689]").text(description); $(".js-view-count[data-work-id=70966689]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 70966689; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='70966689']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 70966689, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "be282564bd44b870871117474e7259e1" } } $('.js-work-strip[data-work-id=70966689]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":70966689,"title":"Phytochemistry and In vitro Antimicrobial Activity of Five Plant Species against Nine Common Human Pathogens","translated_title":"","metadata":{"abstract":"Momordica charantia, Senna podocarpa, Senna alata, Ocimum gratissimum, and Sida acuta which have reportedly been used in folklore for the treatment of various diseases were studied for their antimicrobial activity. Crude methanolic extracts of the leaves were screened for phytochemicals after which they were tested in vitro for activity against clinical isolates of Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa, Proteus vulgaris, Bacillus subtilis, Enterobacter aerogenes, Aspergillus niger, A, flavus and Candida albicans. Phytochemicals present in the extracts included saponins, alkaloids, anthraquinones, tannins, flavonoids and cardiac glycosides. These extracts also showed varying degrees of activity against tested organisms at a concentration range of 15.6 to 500 mg/ml. However, S. acuta showed activity against P. vulgaris, E. aerogenes and As. flavus only. The MIC of the extracts against test organisms ranged from 31.25 to 250 mg/ml. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65217168"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65217168/Detoxification_and_nutritional_enrichment_of_cassava_waste_pulp_using_Rhizopus_oligosporus_and_Aspergillus_niger"><img alt="Research paper thumbnail of Detoxification and nutritional enrichment of cassava waste pulp using Rhizopus oligosporus and Aspergillus niger" class="work-thumbnail" src="https://attachments.academia-assets.com/76914523/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65217168/Detoxification_and_nutritional_enrichment_of_cassava_waste_pulp_using_Rhizopus_oligosporus_and_Aspergillus_niger">Detoxification and nutritional enrichment of cassava waste pulp using Rhizopus oligosporus and Aspergillus niger</a></div><div class="wp-workCard_item"><span>The Annals of the University Dunarea de Jos of Galati. Fascicle VI - Food Technology</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The present study evaluated the detoxification and nutritional enrichment potentials of the ferme...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The present study evaluated the detoxification and nutritional enrichment potentials of the fermented cassava waste pulp obtained through different processing methods of sweet (S) and bitter (B) cassava varieties by fermentation with Rhizopus oligosporus and Aspergillus niger. Four batches [two with both bark and cortex of the tuber removed (S- and B-), two with bark only removed (S+ and B+)] of cassava waste pulp (CWP) were produced from each of S and B varieties. CWP from the four treatments were then subjected to Rhizopus oligosporus, Aspergillus niger, and natural fermentation. Cyanide (mg HCN/kg), phytate (mg/100g), tannin (mg/100g), pH, crude protein (N X6.25) (%), ash (%), Fe, P, K and Ca (mg/100g) content of the unfermented and fermented CWP were determined using standard procedures. The range of the reduction (%) in cyanide content for Rhizopus oligosporus fermented CWP (RCWP), Aspergillus niger fermented CWP (ACWP), and naturally fermented CWP (NCWP) were 86.24 – 91.95, 79...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0ed0237e3743c5ae6f2ccfb630eb0dbd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":76914523,"asset_id":65217168,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/76914523/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65217168"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65217168"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65217168; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65217168]").text(description); $(".js-view-count[data-work-id=65217168]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65217168; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65217168']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 65217168, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0ed0237e3743c5ae6f2ccfb630eb0dbd" } } $('.js-work-strip[data-work-id=65217168]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65217168,"title":"Detoxification and nutritional enrichment of cassava waste pulp using Rhizopus oligosporus and Aspergillus niger","translated_title":"","metadata":{"abstract":"The present study evaluated the detoxification and nutritional enrichment potentials of the fermented cassava waste pulp obtained through different processing methods of sweet (S) and bitter (B) cassava varieties by fermentation with Rhizopus oligosporus and Aspergillus niger. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="65217120"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/65217120/Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria"><img alt="Research paper thumbnail of Application of Atomic Absorption Spectroscopy in the Determination of the Elemental Composition of Chanca piedra (Stone Breaker Leaf) Growing in Iwo, South West Nigeria" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/65217120/Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria">Application of Atomic Absorption Spectroscopy in the Determination of the Elemental Composition of Chanca piedra (Stone Breaker Leaf) Growing in Iwo, South West Nigeria</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus amarus (Euphorbiaceae) was determined using atomic absorption spectroscopy, AAS. Chanca piedra a tropical medicinal plant, is reportedly useful in blocking kidney stone formation and has anti-hepatitis B activity. The acid digested samples were subjected to AAS analysis. The atomic absorption spectrophotometer (PG-990) is a fully automated instrument used in the flame configuration option, controlled by a personal computer, with Microsoft windows as the operating system. Results showed that manganese (Mn) (228.9 ± 3.3 mg/kg), zinc (Zn) (41.7 ± 0.9 mg/kg), iron (Fe) (459.3 ± 3.3 mg/kg), calcium (Ca) (521.9 ± 1.8 mg/kg) and magnesium (Mg) (397.4 ± 1.3 mg/kg) were present in the plant. These high concentrations of calcium, iron and magnesium in this plant should be useful for electrolyte balance, enhancement of growth, bone and teeth formation, and activation of enzyme reactions. It should a...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="65217120"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="65217120"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 65217120; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=65217120]").text(description); $(".js-view-count[data-work-id=65217120]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 65217120; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='65217120']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 65217120, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=65217120]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":65217120,"title":"Application of Atomic Absorption Spectroscopy in the Determination of the Elemental Composition of Chanca piedra (Stone Breaker Leaf) Growing in Iwo, South West Nigeria","translated_title":"","metadata":{"abstract":"The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus amarus (Euphorbiaceae) was determined using atomic absorption spectroscopy, AAS. 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It should a...","publication_date":{"day":null,"month":null,"year":2018,"errors":{}}},"translated_abstract":"The elemental composition of Chanca piedra (stone breaker leaf) alternatively called Phyllantus amarus (Euphorbiaceae) was determined using atomic absorption spectroscopy, AAS. Chanca piedra a tropical medicinal plant, is reportedly useful in blocking kidney stone formation and has anti-hepatitis B activity. The acid digested samples were subjected to AAS analysis. The atomic absorption spectrophotometer (PG-990) is a fully automated instrument used in the flame configuration option, controlled by a personal computer, with Microsoft windows as the operating system. Results showed that manganese (Mn) (228.9 ± 3.3 mg/kg), zinc (Zn) (41.7 ± 0.9 mg/kg), iron (Fe) (459.3 ± 3.3 mg/kg), calcium (Ca) (521.9 ± 1.8 mg/kg) and magnesium (Mg) (397.4 ± 1.3 mg/kg) were present in the plant. These high concentrations of calcium, iron and magnesium in this plant should be useful for electrolyte balance, enhancement of growth, bone and teeth formation, and activation of enzyme reactions. It should a...","internal_url":"https://www.academia.edu/65217120/Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria","translated_internal_url":"","created_at":"2021-12-20T12:52:20.294-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Application_of_Atomic_Absorption_Spectroscopy_in_the_Determination_of_the_Elemental_Composition_of_Chanca_piedra_Stone_Breaker_Leaf_Growing_in_Iwo_South_West_Nigeria","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[],"research_interests":[],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="9206678"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/9206678/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls_CYP2C19_genotypes_in_Nigerian_population"><img alt="Research paper thumbnail of Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population" class="work-thumbnail" src="https://attachments.academia-assets.com/47851341/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/9206678/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls_CYP2C19_genotypes_in_Nigerian_population">Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://pgschoolui.academia.edu/ChinedumBabalola">Chinedum P E A C E Babalola</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://oou.academia.edu/olufunmilayoadejumo">olufunmilayo adejumo</a></span></div><div class="wp-workCard_item"><span>Journal of Clinical Pharmacy and Therapeutics</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a pro-drug used for malaria prophylaxis differently and the frequency of the different alleles may be different in patients with sickle-cell disease (SCD) and normal controls. The objective of this study was to evaluate CYP2C19 *1, *2 and *3 allele and genotype frequencies in Nigerian normal controls and SCD patients, and to further compare variant CYP2C19 frequencies in Nigerians with other African populations.Methods: Genotyping was carried out with PCR and restriction fragment length polymorphism analysis.Results and discussion: CYP2C19 *1 (84·3 vs. 84·9%) or *2 allele frequency (15·7 vs. 15·1%) was not significantly different between patients with SCD and normal subjects. No *3 allele was detected in the cohort. The SCD group exhibited a statistically significantly lower frequency of *1/*1 genotype (69·6%) compared with normal controls (74·4%). Frequency of *2/*2 was significantly lower in SCD (0·9%) compared with normal controls (4·7%). Frequencies of *1/*2 (29·6 vs. 20·9%) were no different in SCD and normal controls.Conclusion: Prevalence of CYP2C19 polymorphisms was defined for the first time in Nigerian normal and SCD populations. Nigerian SCD patients exhibited significantly lower CYP2C19 *1/*1 and *2/*2 frequencies than normal controls. No differences were detected in CYP2C19 allele or genotype frequencies in normal subjects between this study and previous reports in other African populations.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="79704beb30e4abc5a9ef642a49c67d78" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":47851341,"asset_id":9206678,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/47851341/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2NSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="9206678"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="9206678"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 9206678; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=9206678]").text(description); $(".js-view-count[data-work-id=9206678]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 9206678; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='9206678']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 9206678, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "79704beb30e4abc5a9ef642a49c67d78" } } $('.js-work-strip[data-work-id=9206678]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":9206678,"title":"Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population","translated_title":"","metadata":{"abstract":"Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a pro-drug used for malaria prophylaxis differently and the frequency of the different alleles may be different in patients with sickle-cell disease (SCD) and normal controls. The objective of this study was to evaluate CYP2C19 *1, *2 and *3 allele and genotype frequencies in Nigerian normal controls and SCD patients, and to further compare variant CYP2C19 frequencies in Nigerians with other African populations.Methods: Genotyping was carried out with PCR and restriction fragment length polymorphism analysis.Results and discussion: CYP2C19 *1 (84·3 vs. 84·9%) or *2 allele frequency (15·7 vs. 15·1%) was not significantly different between patients with SCD and normal subjects. No *3 allele was detected in the cohort. The SCD group exhibited a statistically significantly lower frequency of *1/*1 genotype (69·6%) compared with normal controls (74·4%). Frequency of *2/*2 was significantly lower in SCD (0·9%) compared with normal controls (4·7%). Frequencies of *1/*2 (29·6 vs. 20·9%) were no different in SCD and normal controls.Conclusion: Prevalence of CYP2C19 polymorphisms was defined for the first time in Nigerian normal and SCD populations. Nigerian SCD patients exhibited significantly lower CYP2C19 *1/*1 and *2/*2 frequencies than normal controls. No differences were detected in CYP2C19 allele or genotype frequencies in normal subjects between this study and previous reports in other African populations.","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"Journal of Clinical Pharmacy and Therapeutics"},"translated_abstract":"Background and objective: Subjects with different CYP2C19 genotypes may metabolize proguanil, a pro-drug used for malaria prophylaxis differently and the frequency of the different alleles may be different in patients with sickle-cell disease (SCD) and normal controls. The objective of this study was to evaluate CYP2C19 *1, *2 and *3 allele and genotype frequencies in Nigerian normal controls and SCD patients, and to further compare variant CYP2C19 frequencies in Nigerians with other African populations.Methods: Genotyping was carried out with PCR and restriction fragment length polymorphism analysis.Results and discussion: CYP2C19 *1 (84·3 vs. 84·9%) or *2 allele frequency (15·7 vs. 15·1%) was not significantly different between patients with SCD and normal subjects. No *3 allele was detected in the cohort. The SCD group exhibited a statistically significantly lower frequency of *1/*1 genotype (69·6%) compared with normal controls (74·4%). Frequency of *2/*2 was significantly lower in SCD (0·9%) compared with normal controls (4·7%). Frequencies of *1/*2 (29·6 vs. 20·9%) were no different in SCD and normal controls.Conclusion: Prevalence of CYP2C19 polymorphisms was defined for the first time in Nigerian normal and SCD populations. Nigerian SCD patients exhibited significantly lower CYP2C19 *1/*1 and *2/*2 frequencies than normal controls. No differences were detected in CYP2C19 allele or genotype frequencies in normal subjects between this study and previous reports in other African populations.","internal_url":"https://www.academia.edu/9206678/Cytochrome_P450_CYP2C19_genotypes_in_Nigerian_sickle_cell_disease_patients_and_normal_controls_CYP2C19_genotypes_in_Nigerian_population","translated_internal_url":"","created_at":"2014-11-09T09:19:20.980-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":21090018,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":33255924,"work_id":9206678,"tagging_user_id":21090018,"tagged_user_id":null,"co_author_invite_id":1502807,"email":"s***r@temple.edu","display_order":0,"name":"Swati Nagar","title":"Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian population"},{"id":33255925,"work_id":9206678,"tagging_user_id":21090018,"tagged_user_id":2660325,"co_author_invite_id":null,"email":"f***o@yahoo.co.uk","affiliation":"Olabisi Onabanjo University","display_order":4194304,"name":"olufunmilayo adejumo","title":"Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls: CYP2C19 genotypes in Nigerian 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href="https://www.academia.edu/54031439/Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry"><img alt="Research paper thumbnail of Elevated Iron Levels in Machine-Grinded Cassava (Manihot esculenta, Euphorbiaceae) in Iwo, Southwest Nigeria as Determined by Atomic Absorption Spectrometry" class="work-thumbnail" src="https://attachments.academia-assets.com/70591958/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/54031439/Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry">Elevated Iron Levels in Machine-Grinded Cassava (Manihot esculenta, Euphorbiaceae) in Iwo, Southwest Nigeria as Determined by Atomic Absorption Spectrometry</a></div><div class="wp-workCard_item"><span>Journal of Food Studies</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The potential of trace amounts of elements to contaminate food during processing in some local co...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The potential of trace amounts of elements to contaminate food during processing in some local communities of Nigeria has since been a subject of concern. In Iwo, South West Nigeria, the processing method of converting the highly perishable cassava tubers to more stable products such as the roasted granular product, Gari involves grating/grinding of peeled cassava tubers and this process is suspected to introduce trace elements into the final product. This study determined and compared the levels of trace elements in peeled and machine-grinded cassava tuber samples. Peeled cassava tuber samples and machine-grinded cassava tuber samples were collected, prepared by acid digestion and filtration. Elemental analysis was carried out using PG-990 Atomic Absorption Spectrophotometer in the flame configuration mode. Iron (9.500 ± 0.025 mg/kg), Copper (11.200 ± 0.025 mg/kg) and Magnesium (251.317 ± 0.038 mg/kg) were present in the peeled cassava tubers; while for the machine-grinded cassava ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b50a9f7b26a099be41e29ecff1784bb5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":70591958,"asset_id":54031439,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/70591958/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="54031439"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="54031439"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 54031439; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=54031439]").text(description); $(".js-view-count[data-work-id=54031439]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 54031439; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='54031439']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 54031439, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b50a9f7b26a099be41e29ecff1784bb5" } } $('.js-work-strip[data-work-id=54031439]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":54031439,"title":"Elevated Iron Levels in Machine-Grinded Cassava (Manihot esculenta, Euphorbiaceae) in Iwo, Southwest Nigeria as Determined by Atomic Absorption Spectrometry","translated_title":"","metadata":{"abstract":"The potential of trace amounts of elements to contaminate food during processing in some local communities of Nigeria has since been a subject of concern. In Iwo, South West Nigeria, the processing method of converting the highly perishable cassava tubers to more stable products such as the roasted granular product, Gari involves grating/grinding of peeled cassava tubers and this process is suspected to introduce trace elements into the final product. This study determined and compared the levels of trace elements in peeled and machine-grinded cassava tuber samples. Peeled cassava tuber samples and machine-grinded cassava tuber samples were collected, prepared by acid digestion and filtration. Elemental analysis was carried out using PG-990 Atomic Absorption Spectrophotometer in the flame configuration mode. Iron (9.500 ± 0.025 mg/kg), Copper (11.200 ± 0.025 mg/kg) and Magnesium (251.317 ± 0.038 mg/kg) were present in the peeled cassava tubers; while for the machine-grinded cassava ...","publisher":"Macrothink Institute, Inc.","publication_name":"Journal of Food Studies"},"translated_abstract":"The potential of trace amounts of elements to contaminate food during processing in some local communities of Nigeria has since been a subject of concern. In Iwo, South West Nigeria, the processing method of converting the highly perishable cassava tubers to more stable products such as the roasted granular product, Gari involves grating/grinding of peeled cassava tubers and this process is suspected to introduce trace elements into the final product. This study determined and compared the levels of trace elements in peeled and machine-grinded cassava tuber samples. Peeled cassava tuber samples and machine-grinded cassava tuber samples were collected, prepared by acid digestion and filtration. Elemental analysis was carried out using PG-990 Atomic Absorption Spectrophotometer in the flame configuration mode. Iron (9.500 ± 0.025 mg/kg), Copper (11.200 ± 0.025 mg/kg) and Magnesium (251.317 ± 0.038 mg/kg) were present in the peeled cassava tubers; while for the machine-grinded cassava ...","internal_url":"https://www.academia.edu/54031439/Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry","translated_internal_url":"","created_at":"2021-09-29T13:16:14.699-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":2660325,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":70591958,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/70591958/thumbnails/1.jpg","file_name":"12315.pdf","download_url":"https://www.academia.edu/attachments/70591958/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Elevated_Iron_Levels_in_Machine_Grinded.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/70591958/12315-libre.pdf?1632950216=\u0026response-content-disposition=attachment%3B+filename%3DElevated_Iron_Levels_in_Machine_Grinded.pdf\u0026Expires=1732460265\u0026Signature=R~Q4UiREoQcRt2KuVlK3esQbpFqBi9QBiDv8EQp12QIvWZtLA~zQZKyWS8fWGj8p-Dzua2nnCuc9X1IQaBdFm7Yup8RQAe2D3aJ4aGCi0feaF0naa4kS7SpfPZtaY5QNIkYQ4cJ3Wq6yOK1fpnQZYGBbP6n7DtwqrJDZ~A1Uw4ni9tghHh6PSHI8pwvmnDltw7TSaZ1HOluqLnvCQN7jIaNrgKsSRnJzuKq1VLZpFawV1l9JSwGOqb0g2vbrhHfZ5k9hP99P8UWDL6F5STrmO3WCvrc1Wue59MS3BTxaObSHW3JnJu5w4y9D4os36CGP1AultfQosx6dVorYfJ0~aA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Elevated_Iron_Levels_in_Machine_Grinded_Cassava_Manihot_esculenta_Euphorbiaceae_in_Iwo_Southwest_Nigeria_as_Determined_by_Atomic_Absorption_Spectrometry","translated_slug":"","page_count":8,"language":"en","content_type":"Work","owner":{"id":2660325,"first_name":"olufunmilayo","middle_initials":"","last_name":"adejumo","page_name":"olufunmilayoadejumo","domain_name":"oou","created_at":"2012-10-17T00:19:00.032-07:00","display_name":"olufunmilayo adejumo","url":"https://oou.academia.edu/olufunmilayoadejumo"},"attachments":[{"id":70591958,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/70591958/thumbnails/1.jpg","file_name":"12315.pdf","download_url":"https://www.academia.edu/attachments/70591958/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Elevated_Iron_Levels_in_Machine_Grinded.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/70591958/12315-libre.pdf?1632950216=\u0026response-content-disposition=attachment%3B+filename%3DElevated_Iron_Levels_in_Machine_Grinded.pdf\u0026Expires=1732460265\u0026Signature=R~Q4UiREoQcRt2KuVlK3esQbpFqBi9QBiDv8EQp12QIvWZtLA~zQZKyWS8fWGj8p-Dzua2nnCuc9X1IQaBdFm7Yup8RQAe2D3aJ4aGCi0feaF0naa4kS7SpfPZtaY5QNIkYQ4cJ3Wq6yOK1fpnQZYGBbP6n7DtwqrJDZ~A1Uw4ni9tghHh6PSHI8pwvmnDltw7TSaZ1HOluqLnvCQN7jIaNrgKsSRnJzuKq1VLZpFawV1l9JSwGOqb0g2vbrhHfZ5k9hP99P8UWDL6F5STrmO3WCvrc1Wue59MS3BTxaObSHW3JnJu5w4y9D4os36CGP1AultfQosx6dVorYfJ0~aA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":43678,"name":"Food Studies","url":"https://www.academia.edu/Documents/in/Food_Studies"}],"urls":[{"id":11719785,"url":"http://www.macrothink.org/journal/index.php/jfs/article/viewFile/15287/12315"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="54031424"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/54031424/Physicochemical_Characteristics_and_HPLC_Determination_of_Alpha_Tocopherol_in_Eighteen_Edible_Vegetable_Oils_Marketed_in_Nigeria"><img alt="Research paper thumbnail of Physicochemical Characteristics and HPLC Determination of Alpha-Tocopherol in Eighteen Edible Vegetable Oils Marketed in Nigeria" class="work-thumbnail" src="https://attachments.academia-assets.com/70591840/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/54031424/Physicochemical_Characteristics_and_HPLC_Determination_of_Alpha_Tocopherol_in_Eighteen_Edible_Vegetable_Oils_Marketed_in_Nigeria">Physicochemical Characteristics and HPLC Determination of Alpha-Tocopherol in Eighteen Edible Vegetable Oils Marketed in Nigeria</a></div><div class="wp-workCard_item"><span>Dhaka University Journal of Pharmaceutical Sciences</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Eighteen brands of vegetable oils available in the local market were extracted with n-hexane befo...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Eighteen brands of vegetable oils available in the local market were extracted with n-hexane before analysis for alpha-tocopherol by RP-HPLC method. The chromatographic separation occurred isocratically with methanol-water [96:4%v/v] at 0.9 ml/min flow rate. Tocopheryl acetate was the internal standard and alpha-tocopherol was eluted at 7.87 min. Free fatty acids value [FFAVs], peroxide value [PV], iodine value [IV] and saponification values [SV] were determined as quality parameters. Calibration curve was linear [r2 0.9969] and the method was precise with relative standard deviation of 0.35% and mean recovery, 87.39%. Alpha-tocopherol concentration ranged from 0-9.22 mg/100g with the highest in Tropical sunflower oil [9.22 mg/100g] and the lowest [1.16 mg/100g] in Laziz oil. Alpha-tocopherol was not detected in unbranded, local palm oil. The calculated percentage daily value [% DV] of vitamin E ranged from 0- 8.60%. Significant difference [p&lt;0.05] between % DV and recommended di...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="263ae15da710fc98385b96b4dfea3659" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":70591840,"asset_id":54031424,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/70591840/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="54031424"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="54031424"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 54031424; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=54031424]").text(description); $(".js-view-count[data-work-id=54031424]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 54031424; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='54031424']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 54031424, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "263ae15da710fc98385b96b4dfea3659" } } $('.js-work-strip[data-work-id=54031424]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":54031424,"title":"Physicochemical Characteristics and HPLC Determination of Alpha-Tocopherol in Eighteen Edible Vegetable Oils Marketed in Nigeria","translated_title":"","metadata":{"abstract":"Eighteen brands of vegetable oils available in the local market were extracted with n-hexane before analysis for alpha-tocopherol by RP-HPLC method. The chromatographic separation occurred isocratically with methanol-water [96:4%v/v] at 0.9 ml/min flow rate. Tocopheryl acetate was the internal standard and alpha-tocopherol was eluted at 7.87 min. Free fatty acids value [FFAVs], peroxide value [PV], iodine value [IV] and saponification values [SV] were determined as quality parameters. Calibration curve was linear [r2 0.9969] and the method was precise with relative standard deviation of 0.35% and mean recovery, 87.39%. Alpha-tocopherol concentration ranged from 0-9.22 mg/100g with the highest in Tropical sunflower oil [9.22 mg/100g] and the lowest [1.16 mg/100g] in Laziz oil. Alpha-tocopherol was not detected in unbranded, local palm oil. The calculated percentage daily value [% DV] of vitamin E ranged from 0- 8.60%. Significant difference [p\u0026lt;0.05] between % DV and recommended di...","publisher":"Bangladesh Journals Online (JOL)","publication_name":"Dhaka University Journal of Pharmaceutical Sciences"},"translated_abstract":"Eighteen brands of vegetable oils available in the local market were extracted with n-hexane before analysis for alpha-tocopherol by RP-HPLC method. The chromatographic separation occurred isocratically with methanol-water [96:4%v/v] at 0.9 ml/min flow rate. Tocopheryl acetate was the internal standard and alpha-tocopherol was eluted at 7.87 min. Free fatty acids value [FFAVs], peroxide value [PV], iodine value [IV] and saponification values [SV] were determined as quality parameters. Calibration curve was linear [r2 0.9969] and the method was precise with relative standard deviation of 0.35% and mean recovery, 87.39%. Alpha-tocopherol concentration ranged from 0-9.22 mg/100g with the highest in Tropical sunflower oil [9.22 mg/100g] and the lowest [1.16 mg/100g] in Laziz oil. Alpha-tocopherol was not detected in unbranded, local palm oil. The calculated percentage daily value [% DV] of vitamin E ranged from 0- 8.60%. 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(Moringaceae) grown in Nigeria: In vitro antisickling activity on deoxygenated erythrocyte cells" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/29753789/Moringa_oleifera_Lam_Moringaceae_grown_in_Nigeria_In_vitro_antisickling_activity_on_deoxygenated_erythrocyte_cells">Moringa oleifera Lam. (Moringaceae) grown in Nigeria: In vitro antisickling activity on deoxygenated erythrocyte cells</a></div><div class="wp-workCard_item"><span>Journal of Pharmacy and Bioallied Sciences</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Traditional medicine, which is more available and affordable for the poor uses medicinal plants f...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Traditional medicine, which is more available and affordable for the poor uses medicinal plants for the treatment and management of various ailments, including the sickle cell disease (SCD). About 24 million Nigerians are carriers of this sickled cell gene, while approximately 2.4 million are SCD patients. Moringa oleifera Lam. (Moringaceae) possesses high nutritional value and has been used in folklore medicine to treat various ailments related to pain and inflammation. 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Investigations into the antisickling activities of both crude methanol extracts and the aqueous fractions of the leaf, seed and seed pod of G. kola were carried out using p-hydroxybenzoic acid and normal saline as positive and negative controls respectively. At the tested concentrations of 10.0, 1.0 and 0.1 mg/ml, the leaf extracts exhibited greatest antisickling activity whilst the seed pod had the least antisickling activity. However, it was observed that the activity of methanol extract of the seed pod did not differ significantly (p&gt;0.05) from that of the positive control, p-hydroxybenzoic acid. Results for screened phytochemicals of the investigated parts revealed the presence of saponins, tannins, combined and free anthraquinones. The results infer a preliminary confirmation for the effectiveness and use of Garcinia kola in the management of SCD and its implication in dru...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3465f6ec949e445fc8a1d98754b39df2" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":50209549,"asset_id":29753784,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/50209549/download_file?st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&st=MTczMjQ1NjY2Niw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="29753784"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="29753784"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 29753784; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=29753784]").text(description); $(".js-view-count[data-work-id=29753784]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 29753784; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='29753784']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 29753784, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "3465f6ec949e445fc8a1d98754b39df2" } } $('.js-work-strip[data-work-id=29753784]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":29753784,"title":"Antisickling activities of extracts of leaf, seed and seed pod of Garcinia kola Heckel","translated_title":"","metadata":{"abstract":"Garcinia kola has been hitherto speculated as effective in the management of sickle cell disease (SCD). Investigations into the antisickling activities of both crude methanol extracts and the aqueous fractions of the leaf, seed and seed pod of G. kola were carried out using p-hydroxybenzoic acid and normal saline as positive and negative controls respectively. At the tested concentrations of 10.0, 1.0 and 0.1 mg/ml, the leaf extracts exhibited greatest antisickling activity whilst the seed pod had the least antisickling activity. However, it was observed that the activity of methanol extract of the seed pod did not differ significantly (p\u0026gt;0.05) from that of the positive control, p-hydroxybenzoic acid. Results for screened phytochemicals of the investigated parts revealed the presence of saponins, tannins, combined and free anthraquinones. 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Using both crude methanol extract and its aqueous fraction, in vitro antisickling activities of these plant parts were evaluated using p-hydroxybenzoic acid and normal saline as positive and negative controls, respectively. Phytochemical screening of the investigated plant specimens revealed the presence of flavonoids, saponnins, alkaloids, tannins, cardiac glycosides free and combined anthraquinones. Extracts/fractions of P. zeylanica had a significantly higher (p \u003c 0.05) antisickling activity at the tested concentrations of 10.0, 1.0 and 0.1 mg/ml. Therefore, the use of these plants by the traditional medical practitioners in the treatment of SCD in Ogun State, Nigeria is justified. 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