CINXE.COM
Alzheimer Disease & Associated Disorders
<!DOCTYPE html> <html dir="ltr" lang="en-US"> <head> <script type='text/javascript' data-ot-ignore>const otAllowScripts = ['/init.js']; new MutationObserver(function (d) { Array.prototype.forEach.call(d, function (g) { Array.prototype.forEach.call(g.addedNodes, function (e) { try { if ('script' === e.tagName?.toLowerCase() && otAllowScripts.some(s => e.src?.includes(s))) { e.setAttribute('data-ot-ignore', ''); } } catch (err) { console.error(err); } }) }) }).observe(document.documentElement, { childList: !0, subtree: !0, attributes: !0, attributeFilter: ['src'] });</script> <!-- OneTrust Cookies Consent Notice start for journals.lww.com --> <script type="text/javascript" src="https://cdn.cookielaw.org/consent/7537629c-faa0-40ce-a837-f7b14c0d4e70/OtAutoBlock.js"></script> <script src="https://cdn.cookielaw.org/scripttemplates/otSDKStub.js" type="text/javascript" charset="UTF-8" data-domain-script="7537629c-faa0-40ce-a837-f7b14c0d4e70"></script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/lww-cookiepro.js?v=05.24.00.023"> </script> <title> Alzheimer Disease & Associated Disorders </title> <!--Google Analytics --> <!-- Google Tag Manager --> <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.setAttributeNode(d.createAttribute('data-ot-ignore'));j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-NLR6H6W');</script> <!-- End Google Tag Manager --> <meta name="GENERATOR" content="Microsoft SharePoint" /><meta http-equiv="Content-type" content="text/html; charset=utf-8" /><meta http-equiv="X-UA-Compatible" content="IE=edge" /><script type="text/javascript">window.NREUM||(NREUM={});NREUM.info = {"beacon":"bam.nr-data.net","errorBeacon":"bam.nr-data.net","licenseKey":"NRJS-310e337bbb542715b7f","applicationID":"1029107228","transactionName":"ZgdWMRZUVkVSBUBbCl9NdTY0GllaSQ5RWwhUEF4KEUdWV19Ja1EERQNYCgNGF1tSFUBXF0EDUwBLUUFYUgtdURVQBVEJBUxXQ0dIVUEVSQ==","queueTime":1,"applicationTime":176,"agent":"","atts":""}</script><script type="text/javascript">(window.NREUM||(NREUM={})).init={privacy:{cookies_enabled:true},ajax:{deny_list:["bam.nr-data.net"]},distributed_tracing:{enabled:true}};(window.NREUM||(NREUM={})).loader_config={agentID:"1103305545",accountID:"2792772",trustKey:"1191223",xpid:"VgEOU1FUChABVFNbBgEAVFYJ",licenseKey:"NRJS-310e337bbb542715b7f",applicationID:"1029107228"};;/*! For license information please see nr-loader-spa-1.274.0.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>u});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function u(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>h,gD:()=>g,xN:()=>p});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const u="[data-nr-mask]",d=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(u):""===t||null===t?e.mask_selector=u:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function p(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,d());const r=(0,s.nY)(e);r&&(r.init=l[e])}function g(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=>{"use strict";r.d(t,{a:()=>c,o:()=>s});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error("All loader-config objects require an agent identifier!");if(!a[e])throw new Error("LoaderConfig for ".concat(e," was never set"));return a[e]}function c(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.loader_config=a[e])}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},u={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},d={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!d[e])throw new Error("Runtime for ".concat(e," was never set"));return d[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");d[e]={...(0,n.a)(t,u),...c},Object.hasOwnProperty.call(d[e],"harvestCount")||Object.defineProperty(d[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=d[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,Yq:()=>a,xv:()=>n});const n="1.274.0",i="PROD",o="CDN",a="^2.0.0-alpha.17"},6154:(e,t,r)=>{"use strict";r.d(t,{A4:()=>s,OF:()=>d,RI:()=>i,WN:()=>h,bv:()=>o,gm:()=>a,lR:()=>f,m:()=>u,mw:()=>c,sb:()=>l});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s="complete"===a?.document?.readyState,c=Boolean("hidden"===a?.document?.visibilityState),u=""+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),l=d&&"undefined"==typeof SharedWorker,f=(()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);return Array.isArray(e)&&e.length>=2?+e[1]:0})(),h=Date.now()-(0,n.t)()},7295:(e,t,r)=>{"use strict";r.d(t,{Xv:()=>a,gX:()=>i,iW:()=>o});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t<n.length;t++){var r=n[t];if("*"===r.hostname)return!1;if(s(r.hostname,e.hostname)&&c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e&&e.length)for(var t=0;t<e.length;t++){let r=e[t];if(!r)continue;0===r.indexOf("http://")?r=r.substring(7):0===r.indexOf("https://")&&(r=r.substring(8));const i=r.indexOf("/");let o,a;i>0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a="");let[s]=o.split(":");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length>t.length)&&t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf("/")&&(e=e.substring(1)),0===t.indexOf("/")&&(t=t.substring(1)),""===e||e===t}},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>u});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};d(e),s[e].get(t)||s[e].set(t,r)}function u(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),h(e,t,!1),s[e].size&&f(e))}function d(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(d(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)p(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function p(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>u});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),u=function e(t,r){var n={},s={},d={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:p,addEventListener:p,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(u.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=h(n),c=g(e),d=c.length,l=0;l<d;l++)c[l].apply(a,r);var p=v()[s[e]];p&&p.push([f,e,r,a]);return a},get:m,listeners:g,context:h,buffer:function(e,t){const r=v();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function h(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function p(e,t){n[e]=g(e).concat(t)}function g(e){return n[e]||[]}function m(t){return d[t]=d[t]||e(f,t)}function v(){return f.backlog}}(void 0,"globalEE"),d=(0,n.Zm)();d.ee||(d.ee=u)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,ZF:()=>c,bz:()=>a,el:()=>u});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}function c(){return s(16)}function u(){return s(32)}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>u,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},u={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},7485:(e,t,r)=>{"use strict";r.d(t,{D:()=>i});var n=r(6154);function i(e){if(0===(e||"").indexOf("data:"))return{protocol:"data"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(":")),sameOrigin:t.protocol===n.gm?.location?.protocol&&t.host===n.gm?.location?.host};return r.port&&""!==r.port||("http:"===t.protocol&&(r.port="80"),"https:"===t.protocol&&(r.port="443")),r.pathname&&""!==r.pathname?r.pathname.startsWith("/")||(r.pathname="/".concat(r.pathname)):r.pathname="/",r}catch(e){return{}}}},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},3304:(e,t,r)=>{"use strict";r.d(t,{A:()=>o});var n=r(7836);const i=()=>{const e=new WeakSet;return(t,r)=>{if("object"==typeof r&&null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??""}catch(e){try{n.ee.emit("internal-error",[e])}catch(e){}return""}}},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>d,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>u,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function u(e){let t=a();return t.initializedAgents?.[e]}function d(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=>{"use strict";r.d(t,{u:()=>f});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,u="addEventListener",d="removeEventListener",l="nr@wrapped:".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get("events")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[u,d],"-",p)}function p(e,t){return e[1]}return"getPrototypeOf"in Object&&(a.RI&&h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(u+"-start",(function(e,t){var n=e[1];if(null!==n&&("function"==typeof n||"object"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if("function"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,"fn-",null,e.name||"anonymous"):n}));this.wrapped=e[1]=i}})),t.on(d+"-start",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;"object"==typeof n&&!Object.prototype.hasOwnProperty.call(n,u);)n=Object.getPrototypeOf(n);n&&t(n,...r)}},3434:(e,t,r)=>{"use strict";r.d(t,{Jt:()=>o,YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],u=e[c];d(u)||(e[c]=r(u,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return d(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){u([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,d,l;try{a=this,o=[...arguments],d="function"==typeof n?n(o,a):n||{}}catch(t){u([t,"",[o,a,s],d],e)}i(r+"start",[o,a,s],d,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],d,c),e}finally{i(r+"end",[o,a,l],d,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){u([t,r,n,i],e)}s=a}}}function u(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function d(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},9300:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.ajax},3333:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,Zp:()=>i,mq:()=>s,nf:()=>a,qN:()=>o});const n=r(860).K7.genericEvents,i=["auxclick","click","copy","keydown","paste","scrollend"],o=["focus","blur"],a=4,s=1e3},6774:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.jserrors},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,TZ:()=>a,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log",a=n.K7.logging},3785:(e,t,r)=>{"use strict";r.d(t,{R:()=>c,b:()=>u});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,["API/logging/".concat(c.toLowerCase(),"/called")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function u(e){return"string"==typeof e&&Object.values(s.p_).some((t=>t===e.toUpperCase().trim()))}},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{BB:()=>d,G4:()=>o,Qb:()=>l,TZ:()=>i,Ug:()=>a,_s:()=>s,bc:()=>u,yP:()=>c});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},u={RESET:{message:"Session was reset",sm:"Reset"},IMPORT:{message:"Recorder failed to import",sm:"Import"},TOO_MANY:{message:"429: Too Many Requests",sm:"Too-Many"},TOO_BIG:{message:"Payload was too large",sm:"Too-Big"},CROSS_TAB:{message:"Session Entity was set to OFF on another tab",sm:"Cross-Tab"},ENTITLEMENTS:{message:"Session Replay is not allowed and will not be started",sm:"Entitlement"}},d=5e3,l={API:"api"}},5270:(e,t,r)=>{"use strict";r.d(t,{Aw:()=>c,CT:()=>u,SR:()=>s});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO&&(0,o.V)(e)&&!0===(0,i.gD)(e,"session_trace.enabled")}function c(e){return!0===(0,i.gD)(e,"session_replay.preload")&&s(e)}function u(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=>{"use strict";r.d(t,{He:()=>i,Kp:()=>s,Lc:()=>u,Rz:()=>d,TZ:()=>n,bD:()=>o,d3:()=>a,jx:()=>l,uP:()=>c});const n=r(860).K7.sessionTrace,i="bstResource",o="resource",a="-start",s="-end",c="fn"+a,u="fn"+s,d="pushState",l=1e3},3962:(e,t,r)=>{"use strict";r.d(t,{AM:()=>o,O2:()=>s,Qu:()=>c,TZ:()=>a,ih:()=>u,tC:()=>i});var n=r(860);const i=["click","keydown","submit"],o="api",a=n.K7.softNav,s={INITIAL_PAGE_LOAD:"",ROUTE_CHANGE:1,UNSPECIFIED:2},c={INTERACTION:1,AJAX:2,CUSTOM_END:3,CUSTOM_TRACER:4},u={IP:"in progress",FIN:"finished",CAN:"cancelled"}},7378:(e,t,r)=>{"use strict";r.d(t,{$p:()=>x,BR:()=>b,Kp:()=>R,L3:()=>y,Lc:()=>c,NC:()=>o,SG:()=>d,TZ:()=>i,U6:()=>p,UT:()=>m,d3:()=>w,dT:()=>f,e5:()=>A,gx:()=>v,l9:()=>l,oW:()=>h,op:()=>g,rw:()=>u,tH:()=>E,uP:()=>s,wW:()=>T,xq:()=>a});var n=r(384);const i=r(860).K7.spa,o=["click","submit","keypress","keydown","keyup","change"],a=999,s="fn-start",c="fn-end",u="cb-start",d="api-ixn-",l="remaining",f="interaction",h="spaNode",p="jsonpNode",g="fetch-start",m="fetch-done",v="fetch-body-",b="jsonp-end",y=(0,n.dV)().o.ST,w="-start",R="-end",x="-body",T="cb"+R,A="jsTime",E="fetch"},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=>{"use strict";r.d(t,{V:()=>o});var n=r(9417),i=r(6154);const o=e=>i.RI&&!0===(0,n.gD)(e,"privacy.cookies_enabled")},425:(e,t,r)=>{"use strict";r.d(t,{j:()=>j});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),u=r(5289),d=r(6154),l=r(944),f=r(3969),h=r(384),p=r(6344);const g=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",p.G4.RECORD,p.G4.PAUSE,"log","wrapLogger"],m=["setErrorHandler","finished","addToTrace","addRelease"];var v=r(1863),b=r(2614),y=r(993),w=r(3785),R=r(2646),x=r(3434);function T(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,x.YM)(i),a=new R.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function A(){const e=(0,h.pV)();g.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),N=r(5603),O=r(5284);const _=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let I=!1;function j(e,t={},g,R){let{init:x,info:j,loader_config:P,runtime:C={},exposed:k=!0}=t;C.loaderType=g;const L=(0,h.pV)();j||(x=L.init,j=L.info,P=L.loader_config),(0,S.xN)(e.agentIdentifier,x||{}),(0,N.a)(e.agentIdentifier,P||{}),j.jsAttributes??={},d.bv&&(j.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,j);const H=(0,S.D0)(e.agentIdentifier),D=[j.beacon,j.errorBeacon];I||(H.proxy.assets&&(_(H.proxy.assets),D.push(H.proxy.assets)),H.proxy.beacon&&D.push(H.proxy.beacon),A(),(0,h.US)("activatedFeatures",O.B),e.runSoftNavOverSpa&&=!0===H.soft_navigations.enabled&&H.feature_flags.includes("soft_nav")),C.denyList=[...H.ajax.deny_list||[],...H.ajax.block_internal?D:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,"api");const g={};var R=s.ee.get(e),x=R.get("tracer");E[e]=b.g.OFF,R.on(p.G4.REPLAY_RUNNING,(t=>{E[e]=t}));var A="api-",S=A+"ixn-";function N(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?"session":void 0)(t,r)}function O(){}g.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,R),(0,w.R)(R,e,t,r)},g.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,R),T(R,e,t,{customAttributes:r,level:i})},m.forEach((e=>{g[e]=I(A,e,!0,"api")})),g.addPageAction=I(A,"addPageAction",!0,n.K7.genericEvents),g.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,I(A,"setPageViewName",!0)()},g.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return N(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},g.setUserId=function(e){if("string"==typeof e||null===e)return N("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},g.setApplicationVersion=function(e){if("string"==typeof e||null===e)return N("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},g.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,R),R.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},g[p.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.RECORD,[],void 0,n.K7.sessionReplay,R)},g[p.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.PAUSE,[],void 0,n.K7.sessionReplay,R)},g.interaction=function(e){return(new O).get("object"==typeof e?e:{})};const _=O.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,R),h||(0,a.p)(S+"tracer",[(0,v.t)(),e,r],i,n.K7.spa,R),function(){if(x.emit((o?"":"no-")+"fn-start",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw x.emit("fn-err",[arguments,this,t],r),t}finally{x.emit("fn-end",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,R),i&&(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,R),r?void 0:this}}function j(){r.e(478).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),R.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{_[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),g.setCurrentRouteName=h?I(S,"routeName",void 0,n.K7.softNav):I(A,"routeName",!0,n.K7.spa),g.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,R),(0,a.p)("err",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,R)},d.RI?(0,u.GG)((()=>j()),!0):j(),g}(e.agentIdentifier,R,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=k),I=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>({212:"nr-spa-compressor",249:"nr-spa-recorder",478:"nr-spa"}[e]+"-1.274.0.min.js"),i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.274.0.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var u=document.getElementsByTagName("script"),d=0;d<u.length;d++){var l=u[d];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={478:"sha512-1vUqEfJPB8Pihje9mv5CfYgkitO1FWcS+UQb84DbXqP8oYctRv4/lzl/MzNLPlRhcY1WVDBGL20I8vm6s2VV7g==",249:"sha512-Y/BeZAh6VSTmUtUNmS5XdyKxL92s30Fyyj8xVW76HSPxcKItL4+x2+kGMZc8pMJnUpZDz1L4eftZQAJh3D8NnA==",212:"sha512-Gn2tQ3qog5Yhrx/gRutkSTYPp+7nkKFt4/mIXg99LxcNpMDAYJZDBYmAACdoHNM86+iq1F3cBcQotFNzjIX8bw=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var h=(t,n)=>{s.onerror=s.onload=null,clearTimeout(p);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},p=setTimeout(h.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={38:0,788:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,u=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);u<a.length;u++)o=a[u],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.274.0.PROD"]=self["webpackChunk:NRBA-1.274.0.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function u(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var d=i(425);var l=i(1687),f=i(4234),h=i(5289),p=i(6154),g=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,v.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(478).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(478).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(478).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};p.RI?(0,h.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,g.SR)(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class w extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var R=i(384);var x=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class N extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),p.RI&&((0,T.u)((()=>(0,x.p)("docHidden",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)("pagehide",(()=>(0,x.p)("winPagehide",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class _ extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),j=i(3304);class P{constructor(e,t,r,n,i){this.name="UncaughtError",this.message="string"==typeof e?e:(0,j.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return H(e)?e:new P(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t="Unhandled Promise Rejection";if(!e?.reason)return;if(H(e.reason))try{return e.reason.message=t+": "+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+": "+r?.message,r}function L(e){if(e.error instanceof SyntaxError&&!/:\d+$/.test(e.error.stack?.trim())){const t=new P(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return H(e.error)?e.error:C(e)}function H(e){return e instanceof Error&&!!e.stack}class D extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on("internal-error",(e=>{this.abortHandler&&(0,x.p)("ierr",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.#r=e})),p.gm.addEventListener("unhandledrejection",(e=>{this.abortHandler&&(0,x.p)("err",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),p.gm.addEventListener("error",(e=>{this.abortHandler&&(0,x.p)("err",[L(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var M=i(8990);let K=1;const U="nr@id";function V(e){const t=typeof e;return!e||"object"!==t&&"function"!==t?-1:e===p.gm?0:(0,M.I)(e,U,(function(){return K++}))}function G(e){if("string"==typeof e&&e.length)return e.length;if("object"==typeof e){if("undefined"!=typeof ArrayBuffer&&e instanceof ArrayBuffer&&e.byteLength)return e.byteLength;if("undefined"!=typeof Blob&&e instanceof Blob&&e.size)return e.size;if(!("undefined"!=typeof FormData&&e instanceof FormData))try{return(0,j.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=["open","send"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get("xhr")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=p.gm.XMLHttpRequest,a=p.gm.MutationObserver,s=p.gm.Promise,c=p.gm.setInterval,u="readystatechange",d=["onload","onerror","onabort","onloadstart","onloadend","onprogress","ontimeout"],l=[],f=p.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit("new-xhr",[r],a),r.addEventListener(u,(s=a,function(){var e=this;e.readyState>3&&!s.resolved&&(s.resolved=!0,n.emit("xhr-resolved",[],e)),i.inPlace(e,d,"fn-",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit("internal-error",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,["onreadystatechange"],"fn-",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,"-xhr-",y),n.on("send-xhr-start",(function(e,t){h(e,t),function(e){l.push(e),a&&(g?g.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on("open-xhr-start",h),a){var g=s&&s.resolve();if(!c&&!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on("fn-end",(function(e){e[0]&&e[0].type===u||b()}));function b(){for(var e=0;e<l.length;e++)h(0,l[e]);l.length&&(l=[])}function y(e,t){return t}return n}var Y="fetch-",X=Y+"body-",J=["arrayBuffer","blob","json","text","formData"],Q=p.gm.Request,ee=p.gm.Response,te="prototype";const re={};function ne(e){const t=function(e){return(e||B.ee).get("fetch")}(e);if(!(Q&&ee&&p.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];"function"==typeof i&&(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+"before-start",[r],o),o[B.P]&&o[B.P].dt&&(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+"start",[r,e],a),a.then((function(e){return t.emit(n+"end",[null,e],a),e}),(function(e){throw t.emit(n+"end",[e],a),e}))})}return re[t.debugId]=1,J.forEach((e=>{r(Q[te],e,X),r(ee[te],e,X)})),r(p.gm,"fetch",Y),t.on(Y+"end",(function(e,r){var n=this;if(r){var i=r.headers.get("content-length");null!==i&&(n.rxSize=i),t.emit(Y+"done",[null,r],n)}else t.emit(Y+"done",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||"").toString()||null,i=(t.agentID||"").toString()||null,o=(t.trustKey||"").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),u={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)&&this.useTraceContextHeadersForCors())&&(u.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),u.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin&&!this.excludeNewrelicHeader()||!e.sameOrigin&&this.isAllowedOrigin(e)&&this.useNewrelicHeaderForCors())&&(u.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),u}generateTraceContextParentHeader(e,t){return"00-"+t+"-"+e+"-01"}generateTraceContextStateHeader(e,t,r,n,i){return i+"@nr=0-1-"+r+"-"+n+"-"+e+"----"+t}generateTraceHeader(e,t,r,n,i,o){if(!("function"==typeof p.gm?.btoa))return null;var a={v:[0,1],d:{ty:"Browser",ac:n,ap:i,id:e,tr:t,ti:r}};return o&&n!==o&&(a.d.tk=o),btoa((0,j.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()&&this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,"distributed_tracing")&&(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n<r.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname&&e.protocol===i.protocol&&e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),ue=["load","error","abort","timeout"],de=ue.length,le=(0,R.dV)().o.REQ,fe=(0,R.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=>(0,x.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:"xhr",fetch:"fetch",beacon:"beacon"};p.gm?.performance?.getEntriesByType("resource").forEach((t=>{if(t.initiatorType in e&&0!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};pe(r,t.name),this.handler("xhr",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=R,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener("load",(function(r){T(t,e)}),(0,A.jT)(!1)),p.lR||e.addEventListener("progress",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},pe(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid&&this.sameOrigin&&r.setRequestHeader("X-NewRelic-ID",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader&&(r.setRequestHeader("newrelic",i.newrelicHeader),o=!0),i.traceContextParentHeader&&(r.setRequestHeader("traceparent",i.traceContextParentHeader),i.traceContextStateHeader&&r.setRequestHeader("tracestate",i.traceContextStateHeader),o=!0),o&&(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n&&i){var a=G(i);a&&(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{"abort"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),("load"!==e.type||o.called===o.totalCbs&&(o.onloadCalled||"function"!=typeof r.onload)&&"function"==typeof o.end)&&o.end(r)}catch(e){try{t.emit("internal-error",[e])}catch(e){}}};for(var s=0;s<de;s++)r.addEventListener(ue[s],this.listener,(0,A.jT)(!1))}function u(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled&&"function"==typeof r.onload||"function"!=typeof this.end||this.end(r)}function d(e,t){var r=""+V(e)+!!t;this.xhrGuids&&!this.xhrGuids[r]&&(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=""+V(e)+!!t;this.xhrGuids&&this.xhrGuids[r]&&(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-added",[e[1],e[2]],r)}function g(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-removed",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe&&("onload"===r&&(this.onload=!0),("load"===(e[0]&&e[0].type)||this.onload)&&(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart&&t.emit("xhr-cb-time",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if("string"==typeof e[0]?0===(t=e[0]).length&&p.RI&&(t=""+p.gm.location.href):e[0]&&e[0].url?t=e[0].url:p.gm?.URL&&e[0]&&e[0]instanceof URL?t=e[0].href:"function"==typeof e[0].toString&&(t=e[0].toString()),"string"==typeof t&&0!==t.length){t&&(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i&&(i.newrelicHeader||i.traceContextParentHeader))if(e[0]&&e[0].headers)s(e[0].headers,i)&&(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)&&(this.dt=i),e.length>1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader&&(e.set("newrelic",t.newrelicHeader),r=!0),t.traceContextParentHeader&&(e.set("traceparent",t.traceContextParentHeader),t.traceContextStateHeader&&e.set("tracestate",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length>=1&&(this.target=e[0]),e.length>=2&&(this.opts=e[1]);var r,n=this.opts||{},i=this.target;"string"==typeof i?r=i:"object"==typeof i&&i instanceof le?r=i.url:p.gm?.URL&&"object"==typeof i&&i instanceof URL&&(r=i.href),pe(this,r);var o=(""+(i&&i instanceof le&&i.method||n.method||"GET")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function w(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,"string"==typeof this.rxSize&&this.rxSize.length>0&&(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r("xhr",[this.params,i,this.startTime,this.endTime,"fetch"],this,a.K7.ajax)}function R(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t<de;t++)e.removeEventListener(ue[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status&&(t.status=0):T(this,e),n.cbTime=this.cbTime,r("xhr",[t,n,this.startTime,this.endTime,"xhr"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return"json"===r&&null!==t?t:"arraybuffer"===r||"blob"===r||"json"===r?G(e.response):"text"===r||""===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n&&(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader("X-NewRelic-App-Data");i&&((0,x.p)(O.rs,["Ajax/CrossApplicationTracing/Header/Seen"],void 0,a.K7.metrics,t),e.params.cat=i.split(", ").pop())}e.loadCaptureCalled=!0}t.on("new-xhr",i),t.on("open-xhr-start",o),t.on("open-xhr-end",s),t.on("send-xhr-start",c),t.on("xhr-cb-time",u),t.on("xhr-load-added",d),t.on("xhr-load-removed",l),t.on("xhr-resolved",f),t.on("addEventListener-end",h),t.on("removeEventListener-end",g),t.on("fn-end",v),t.on("fetch-before-start",b),t.on("fetch-start",y),t.on("fn-start",m),t.on("fetch-done",w)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function pe(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+":"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const ge={},me=["pushState","replaceState"];function ve(e){const t=function(e){return(e||B.ee).get("history")}(e);return!p.RI||ge[t.debugId]++||(ge[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,"-")),t}var be=i(3738);const{He:ye,bD:we,d3:Re,Kp:xe,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class Ne extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,x.p)("bst",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+Re,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+xe,(function(e){(0,x.p)("bstHist",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=>{const t=e.getEntries();(0,x.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:we,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class _e extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem("".concat(Oe.H3,"_").concat(Oe.uh)))}catch(e){}(0,g.SR)(e.agentIdentifier)&&this.ee.on(t.G4.RECORD,(()=>this.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on("err",(e=>{this.replayRunning&&(this.errorNoticed=!0,(0,x.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.replayRunning=e}))}#s(e){return e&&(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,g.Aw)(this.agentIdentifier)}#u=!1;async#c(e){if(!this.#u){this.#u=!0;try{const{Recorder:t}=await Promise.all([i.e(478),i.e(249)]).then(i.bind(i,8589));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL&&this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder&&this.recorder.parent.mode!==Oe.g.FULL&&(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3962);class je extends b{static featureName=Ie.TZ;constructor(e,t=!0){if(super(e,Ie.TZ,t),!p.RI||!(0,R.dV)().o.MO)return;const r=ve(this.ee);Ie.tC.forEach((e=>{(0,A.sp)(e,(e=>{a(e)}),!0)}));const n=()=>(0,x.p)("newURL",[(0,S.t)(),""+window.location],void 0,this.featureName,this.ee);r.on("pushState-end",n),r.on("replaceState-end",n);try{this.removeOnAbort=new AbortController}catch(e){}(0,A.sp)("popstate",(e=>(0,x.p)("newURL",[e.timeStamp,""+window.location],void 0,this.featureName,this.ee)),!0,this.removeOnAbort?.signal);let i=!1;const o=new((0,R.dV)().o.MO)(((e,t)=>{i||(i=!0,requestAnimationFrame((()=>{(0,x.p)("newDom",[(0,S.t)()],void 0,this.featureName,this.ee),i=!1})))})),a=(0,v.s)((e=>{(0,x.p)("newUIEvent",[e],void 0,this.featureName,this.ee),o.observe(document.body,{attributes:!0,childList:!0,subtree:!0,characterData:!0})}),100,{leading:!0});this.abortHandler=function(){this.removeOnAbort?.abort(),o.disconnect(),this.abortHandler=void 0},this.importAggregator(e,{domObserver:o})}}var Pe=i(7378);const Ce={},ke=["appendChild","insertBefore","replaceChild"];function Le(e){const t=function(e){return(e||B.ee).get("jsonp")}(e);if(!p.RI||Ce[t.debugId])return t;Ce[t.debugId]=!0;var r=(0,W.YM)(t),n=/[?&](?:callback|cb)=([^&#]+)/,i=/(.*)\.([^.]+)/,o=/^(\w+)(\.|$)(.*)$/;function a(e,t){if(!e)return t;const r=e.match(o),n=r[1];return a(r[3],t[n])}return r.inPlace(Node.prototype,ke,"dom-"),t.on("dom-start",(function(e){!function(e){if(!e||"string"!=typeof e.nodeName||"script"!==e.nodeName.toLowerCase())return;if("function"!=typeof e.addEventListener)return;var o=(s=e.src,c=s.match(n),c?c[1]:null);var s,c;if(!o)return;var u=function(e){var t=e.match(i);if(t&&t.length>=3)return{key:t[2],parent:a(t[1],window)};return{key:e,parent:window}}(o);if("function"!=typeof u.parent[u.key])return;var d={};function l(){t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}function f(){t.emit("jsonp-error",[],d),t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}r.inPlace(u.parent,[u.key],"cb-",d),e.addEventListener("load",l,(0,A.jT)(!1)),e.addEventListener("error",f,(0,A.jT)(!1)),t.emit("new-jsonp",[e.src],d)}(e[0])})),t}const He={};function De(e){const t=function(e){return(e||B.ee).get("promise")}(e);if(He[t.debugId])return t;He[t.debugId]=!0;var r=t.context,n=(0,W.YM)(t),i=p.gm.Promise;return i&&function(){function e(r){var o=t.context(),a=n(r,"executor-",o,null,!1);const s=Reflect.construct(i,[a],e);return t.context(s).getCtx=function(){return o},s}p.gm.Promise=e,Object.defineProperty(e,"name",{value:"Promise"}),e.toString=function(){return i.toString()},Object.setPrototypeOf(e,i),["all","race"].forEach((function(r){const n=i[r];e[r]=function(e){let i=!1;[...e||[]].forEach((e=>{this.resolve(e).then(a("all"===r),a(!1))}));const o=n.apply(this,arguments);return o;function a(e){return function(){t.emit("propagate",[null,!i],o,!1,!1),i=i||!e}}}})),["resolve","reject"].forEach((function(r){const n=i[r];e[r]=function(e){const r=n.apply(this,arguments);return e!==r&&t.emit("propagate",[e,!0],r,!1,!1),r}})),e.prototype=i.prototype;const o=i.prototype.then;i.prototype.then=function(...e){var i=this,a=r(i);a.promise=i,e[0]=n(e[0],"cb-",a,null,!1),e[1]=n(e[1],"cb-",a,null,!1);const s=o.apply(this,e);return a.nextPromise=s,t.emit("propagate",[i,!0],s,!1,!1),s},i.prototype.then[W.Jt]=o,t.on("executor-start",(function(e){e[0]=n(e[0],"resolve-",this,null,!1),e[1]=n(e[1],"resolve-",this,null,!1)})),t.on("executor-err",(function(e,t,r){e[1](r)})),t.on("cb-end",(function(e,r,n){t.emit("propagate",[n,!0],this.nextPromise,!1,!1)})),t.on("propagate",(function(e,r,n){this.getCtx&&!r||(this.getCtx=function(){if(e instanceof Promise)var r=t.context(e);return r&&r.getCtx?r.getCtx():this})}))}(),t}const Me={},Ke="setTimeout",Ue="setInterval",Ve="clearTimeout",Ge="-start",Fe=[Ke,"setImmediate",Ue,Ve,"clearImmediate"];function Be(e){const t=function(e){return(e||B.ee).get("timer")}(e);if(Me[t.debugId]++)return t;Me[t.debugId]=1;var r=(0,W.YM)(t);return r.inPlace(p.gm,Fe.slice(0,2),Ke+"-"),r.inPlace(p.gm,Fe.slice(2,3),Ue+"-"),r.inPlace(p.gm,Fe.slice(3),Ve+"-"),t.on(Ue+Ge,(function(e,t,n){e[0]=r(e[0],"fn-",null,n)})),t.on(Ke+Ge,(function(e,t,n){this.method=n,this.timerDuration=isNaN(e[1])?0:+e[1],e[0]=r(e[0],"fn-",this,n)})),t}const We={};function ze(e){const t=function(e){return(e||B.ee).get("mutation")}(e);if(!p.RI||We[t.debugId])return t;We[t.debugId]=!0;var r=(0,W.YM)(t),n=p.gm.MutationObserver;return n&&(window.MutationObserver=function(e){return this instanceof n?new n(r(e,"fn-")):n.apply(this,arguments)},MutationObserver.prototype=n.prototype),t}const{TZ:qe,d3:Ze,Kp:Ye,$p:Xe,wW:Je,e5:Qe,tH:$e,uP:et,rw:tt,Lc:rt}=Pe;class nt extends b{static featureName=qe;constructor(e,t=!0){if(super(e,qe,t),!p.RI)return;try{this.removeOnAbort=new AbortController}catch(e){}let r,n=0;const i=this.ee.get("tracer"),o=Le(this.ee),a=De(this.ee),s=Be(this.ee),c=Z(this.ee),u=this.ee.get("events"),d=ne(this.ee),l=ve(this.ee),f=ze(this.ee);function h(e,t){l.emit("newURL",[""+window.location,t])}function g(){n++,r=window.location.hash,this[et]=(0,S.t)()}function m(){n--,window.location.hash!==r&&h(0,!0);var e=(0,S.t)();this[Qe]=~~this[Qe]+e-this[et],this[rt]=e}function v(e,t){e.on(t,(function(){this[t]=(0,S.t)()}))}this.ee.on(et,g),a.on(tt,g),o.on(tt,g),this.ee.on(rt,m),a.on(Je,m),o.on(Je,m),this.ee.on("fn-err",((...t)=>{t[2]?.__newrelic?.[e.agentIdentifier]||(0,x.p)("function-err",[...t],void 0,this.featureName,this.ee)})),this.ee.buffer([et,rt,"xhr-resolved"],this.featureName),u.buffer([et],this.featureName),s.buffer(["setTimeout"+Ye,"clearTimeout"+Ze,et],this.featureName),c.buffer([et,"new-xhr","send-xhr"+Ze],this.featureName),d.buffer([$e+Ze,$e+"-done",$e+Xe+Ze,$e+Xe+Ye],this.featureName),l.buffer(["newURL"],this.featureName),f.buffer([et],this.featureName),a.buffer(["propagate",tt,Je,"executor-err","resolve"+Ze],this.featureName),i.buffer([et,"no-"+et],this.featureName),o.buffer(["new-jsonp","cb-start","jsonp-error","jsonp-end"],this.featureName),v(d,$e+Ze),v(d,$e+"-done"),v(o,"new-jsonp"),v(o,"jsonp-end"),v(o,"cb-start"),l.on("pushState-end",h),l.on("replaceState-end",h),window.addEventListener("hashchange",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("load",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("popstate",(function(){h(0,n>1)}),(0,A.jT)(!0,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var it=i(3333);class ot extends b{static featureName=it.TZ;constructor(e,t=!0){super(e,it.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];p.RI&&e.init.user_actions.enabled&&(it.Zp.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)),!0))),it.qN.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)))))),r.some((e=>e))?this.importAggregator(e):this.deregisterDrain()}}var at=i(993),st=i(3785);class ct extends b{static featureName=at.TZ;constructor(e,t=!0){super(e,at.TZ,t);const r=this.ee;this.ee.on("wrap-logger-end",(function([e]){const{level:t,customAttributes:n}=this;(0,st.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),p.gm?(this.features={},(0,R.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(w),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,d.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=u(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,R.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[he,w,N,Ne,_e,_,D,ot,ct,je,nt],loaderType:"spa"})})()})();</script><meta charset="utf-8" /><meta name="viewport" content="width=device-width, initial-scale=1" /><meta http-equiv="Expires" content="0" /><meta name="WT.cg_n" content="alzheimerjournal" /><meta name="WT.cg_s" content="Register" /><meta name="Description" content="Alzheimer Disease & Associated Disorders is a peer-reviewed, multidisciplinary journal directed to an audience of clinicians and researchers, with primary emphasis on Alzheimer disease and associated disorders. The journal publishes original articles emphasizing research in humans including epidemiologic studies, clinical trials and experimental studies, studies of diagnosis and biomarkers, as well as research on the health of persons with dementia and their caregivers. The scientific portion of the journal is augmented by reviews of the current literature, concepts, conjectures, and hypotheses in dementia, brief reports, and letters to the editor." /><meta name="robots" content="noindex, follow, noarchive" /><meta name="WT.sv" content="ZUSE1PEJPWEB06" /><meta name="Title" content="Alzheimer Disease & Associated Disorders" /><style id="SPThemeHideForms" type="text/css">body {opacity:0 !important}</style> <!-- Head container delegate control --> <link href="https://fonts.googleapis.com/css?family=Arvo:400,400i,700|Fira+Sans:300,300i,400,400i,500,500i,600,600i,700,700i&display=swap" rel="stylesheet" /> <script> // temporary workaround for Bug 316328:[Stage][Registration][Regression 05.04] - Omniture events are not displayed for article viewer page // prevents JS exception in Adobe launch.js caused by situation when wkhealth_institution_type meta tag is present while wkhealth_institution_name tag is not in the page head // see this check in Adobe launch.js: null != document.querySelector("meta[name='wkhealth_institution_name']") ... // TODO: implement proper code fix after release 05.04.00 deployment var wkhealth_institution_type = document.querySelector("meta[name='wkhealth_institution_type']"); var wkhealth_institution_name = document.querySelector("meta[name='wkhealth_institution_name']"); console.warn(wkhealth_institution_type); console.warn(wkhealth_institution_name); if (wkhealth_institution_type && !wkhealth_institution_name) { console.warn('Workaround in release 05.04.00 - removing wkhealth_institution_type meta tag if wkhealth_institution_name is not present'); wkhealth_institution_type.remove(); } </script> <link rel="shortcut icon" href="https://cdn.wolterskluwer.io/wk-logos/1.0.x/favicon.png" type="image/vnd.microsoft.icon" id="favicon" /> <link id="ctl00_ctl14_wkfavicon_linkFavIcon" rel="shortcut icon" href="/alzheimerjournal/PublishingImages/WKfavicon.ico" type="image/x-icon"></link> <meta name="msapplication-TileImage" content="/_layouts/15/images/SharePointMetroAppTile.png" /><meta name="msapplication-TileColor" content="#0072C6" /> <link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/1033/styles/Themable/corev15.css?v=05.24.00.023" media="screen" /> <link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/oaks.journals/core/bootstrap.min.css?v=05.24.00.023" media="screen" /> <link id="ctl00_ctl14_FontAwesomeStylesheet" rel="stylesheet" type="text/css" href="https://unpkg.com/font-awesome@4.4.0/css/font-awesome.min.css"></link> <link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/1033/styles/oaks.journals/bootstrap-overwrites.css?v=05.24.00.023" media="screen" /><link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/1033/styles/oaks.journals/tachyons.css?v=05.24.00.023" media="screen" /><link rel="stylesheet" type="text/css" href="/alzheimerjournal/_layouts/15/1033/styles/oaks.journals/base-main-header.css?v=05.24.00.023" media="screen" /><link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/oaks.journals/core/lww-core.css?v=05.24.00.023" media="screen" /><link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/oaks.journals/core/ejp.css?v=05.24.00.023" media="screen" /><link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/oaks.journals/core/ejp-print.css?v=05.24.00.023" media="print" /><link rel="stylesheet" type="text/css" href="https://lww.com/_layouts/15/oaks.journals/core/jqueryui.css?v=05.24.00.023" media="screen" /> <link rel="stylesheet" type="text/css" href="/alzheimerjournal/Style%20Library/journal.css?v=05.24.00.023" media="screen" /> <link rel="stylesheet" type="text/css" href="/alzheimerjournal/Style%20Library/custom.journal.css?v=05.24.00.023" media="screen" /> <script>var WebContext = {"EndPoints":{"ArticleMetricsEndpoint":"//services.journals.lww.com/IntegrationServices/ArticleMetricsService.svc","ThirdPartyRSSFeedServiceEndPoint":"https://services.journals.lww.com/IntegrationServices/ThirdPartyRSSFeedService.svc","JwtTokenServiceEndpoint":"https://journals.lww.com/alzheimerjournal/_layouts/15/OAKS.Journals/JsonWebToken.svc"}}</script> <script type="text/javascript">// <![CDATA[ var g_SPOffSwitches={}; // ]]> </script> <script type="text/javascript" src="/_layouts/15/1033/initstrings.js?rev=EIwgcAIn5eSIF0jZ5w1WhQ%3D%3DTAG0"></script> <script type="text/javascript" src="/_layouts/15/init.js?rev=zTJw1vV9i5CJeZ52lkKJSQ%3D%3DTAG0"></script> <script type="text/javascript" src="/_layouts/15/theming.js?rev=SuLUbbwTXcxFWOWLFUsOkw%3D%3DTAG0"></script> <script type="text/javascript" src="/ScriptResource.axd?d=F7rjznvAP1ZvjwmSYaDR9a3zqrnKFnNGXs7A_cRIg2rplizpOOjwg9eBfW_KxBMLRVN3lzATjzWkisQusj_Iaw7I7xHhM2EsA2p1WTk5lIh-1_uEIMq1sktVYKM3D6Gp5VSqOtDTEnrScqHWTHOzdCPnKDjm2mtJH72pNbP0u4uI_zDnfi9spPAqI_kz3qnF0&t=ffffffffaa493ab8"></script> <script type="text/javascript" src="/_layouts/15/blank.js?rev=6Epdi%2BEh0XOHrFNRcf4Cwg%3D%3DTAG0"></script> <script type="text/javascript" src="/ScriptResource.axd?d=yatK8ruofouVZAe4qMCnoohEpb3HRGGjDeZZjZ7kMmC722OeAMhxqxkQCI5Rxx8YROZ4ohEXEd-BY-UzqqqylduXIs6jc38C73kN3lT2QdlwTljpny1fYEjcvvbYSMHNq1-TT-bDa0cFUDuAr5ywhChhEELpPbB_In_xfOO6OlgjpjP86LmsgZzKkXo8aCS90&t=ffffffffaa493ab8"></script> <script type="text/javascript" src="/ScriptResource.axd?d=Fr5k7XDliwj7SPEiKSqb-V3uT_yv_Vc0LBq3yd_m1_Ea8vkvI41fPqtWB8rH7kW9D2--SObxiXOCEDDg2Tv5yxNEAylK5ZpV5j9rD03yPUcCPh8w-y9A8MWLSg0jrQ-0kisGzu4Hba8Ct3e6oiiAj5nLa8lUDGLzNSKFrT8wEzRvrGDuqa6AKloxdLDyhLNb6sYlIjtGIn7oUTXlG_HGsg2&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=LXNyktQiaIpbp533FW-c46OHB30ylIqDlrzk7r3HlWeMLy05SwQ7ZZDsPGq7NzzDRSU0tvewepiuVrszZuoio7QLmOYibhCj6dQNfSL2hGpxpyP-E7et27fbWMHpoIuHecopwN8d_b-WR8rimwUGdbN6akitIdX32lXMez7LH7qkG1jVMDvXf2M0_6gdMpGjpPKlEhmMrNGzYuo05_KLRO4TeTkKykcR_5pPB2fyzgk1&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=UozfgYfgcP8g118ZMoKEWz_x5V51ZaIWOeFUe49mdZ8Yy8frQahBfRlFRNNeizXxYfmbtpE1uZMOMW2QeF7QCWjREvRvpNDSCGO5YICh1GalcUtEGJaGvVObluwmGza6-lV8S-wgb9vDF6UYZlWbyLOo-d94ckB8BN1hUlnIdqL9auDE1qR-ddFC7rw_89VZWQ6uTxR6vOlq2jE0iTr3J_6_Q3a7SLOduMua_ZXDgk7k01lBMUodCwi6dm-oTxLE0&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=ZWgxL8bxzPcm3sf7nBtjnXIE2wsAF-izuHnFdkP9YIwhY40NTQZWAMXXd5_I4JNrdCjHASB5kHO0Yp663zuk5AhL_jRl1k_SY5vnpUrSCkFxyolVdXM4FQlXIKn4Vvw31N76GuK5LU06Z_W9PLwfY2Syw-289UtPxVzBx9gVTRruCab2sQxw8wsPzWwQuzodrorJnIINUBwKL_vl4JpUyg2&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=EBaCwkyF6v0hRUf3ae-93ssVmxQ7oIMqv_PPxkqrb9oreHGbb2-nfpYVrHcdp3m-zVM-7IejfExLCflpv83MelmvDxCP_bfWTqE6qeqNKtnJrC6U7f-VSqzDeiqxeFeQcr2gdWPsj6xuQIL9yofEjL-H9aGyCIOqWIpEBJ7whIjP5cINMF1LSl9sjJQ7m8EzvCkRy97Lv87xdtMaOwsPZQua3oe2eRAfQMy5DfH1rBU1&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=wD8VqdUYdbEDwBKpnhKPdzJbzZckynHSZAFSwtw0pb9xBjjkE5QcyWugHeKYmmlr5VSa3nfGB1Xz7jafz_E7BWSKiwSgokhW7jiO928L_QrPFxF6EUuMyF_R_k74O2ZH3Z2j_4YTihok5YYe4jIHNbXew2ICIYicdQ6t5hTNp6rgynp1DalRocxe5znBs87HZLCu8p1QfDK38eKJRZE968HV31IWzfYmG-OLm0YY--COCDBd2W06gq-Q4GGHyVyR0&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=-7EYqBUD5SBnN9GXen_j6q1vUCHCiGsBm9LG-6jUM7Rd46ySBRRKNEzamKwU97Ev4GNWdvuZGqjKPpTco_vaUnZotagIyWjSOr8Y_YpPpCBN41u1qvqUa_Z3KhaMpFpLnBCVAOGXsZBX0gnLdrWl7SPrwgrfSJovgJOyKQNohnCagrVGRS7D0SajjiwZiBwbRFFXzQUODi-UXS4-R3OUE9NEoYmrfX_DvTq3geTEsrQ1&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=1Bz5XD8diaSe1jTYew43lskkqvoOQ7xUk9zYBR9yPfNI5dG64NIPCYkFSKOHNDL_QVi-dGp62xDY0jGHiOTaybK9bApxYHqJLIbzEwEQB4irPiQPiKBzzY5p7N4f-D0FpCNtiMYBBQwavF6nxBbyIVOMdRyTBQ10Hm9Zmj9z2NOmhfNxDVkOcXNQDwO54qpnA74wIl4P7kqB5Ngz9hx4kY3xEadtMKXSX7uqRVTMzso1&t=596f116c"></script> <script type="text/javascript" src="/ScriptResource.axd?d=2jUlVNSVbehJJ-Lt4PSuX3imkArDDoAUwrw500StXDnRKdoHS2np91egmJiBUG7feIOax9x-3d3eG4JYvatg-8X9LQmJU49eWww19gWY7vSdphyQrCWf_QI352TwlgZkOjBO9SLzCdnP0Rkx2chN2q3GkIbDzjCD2z0q_V19F4FLoBgT9FcKUizcWUqIzBoXhgYN9ZOMKI0YCb0cjcqnIG9l7yUe6eYzolUqVyyoo5k1&t=596f116c"></script> <script type="text/javascript">RegisterSod("require.js", "\u002f_layouts\u002f15\u002frequire.js?rev=bv3fWJhk0uFGpVwBxnZKNQ\u00253D\u00253DTAG0");</script> <script type="text/javascript">RegisterSod("strings.js", "\u002f_layouts\u002f15\u002f1033\u002fstrings.js?rev=50XNF7CGsZt5Ek1YPXlC1A\u00253D\u00253DTAG0");</script> <script type="text/javascript">RegisterSod("core.js", "\u002f_layouts\u002f15\u002fcore.js?rev=j9a0d\u00252BPy1yQxnd9MnbVzHQ\u00253D\u00253DTAG0");RegisterSodDep("core.js", "strings.js");</script> <script type="text/javascript">RegisterSod("menu.js", "\u002f_layouts\u002f15\u002fmenu.js?rev=wrJq19VhLDExyMJ5\u00252B8yU0Q\u00253D\u00253DTAG0");</script> <script type="text/javascript">RegisterSod("mQuery.js", "\u002f_layouts\u002f15\u002fmquery.js?rev=NDgkLecAIkz\u00252BweeQGHsFzg\u00253D\u00253DTAG0");</script> <script type="text/javascript">RegisterSod("callout.js", "\u002f_layouts\u002f15\u002fcallout.js?rev=TL9KyIcEAc\u00252BtRfD5o03AZw\u00253D\u00253DTAG0");RegisterSodDep("callout.js", "strings.js");RegisterSodDep("callout.js", "mQuery.js");RegisterSodDep("callout.js", "core.js");</script> <script type="text/javascript">RegisterSod("clienttemplates.js", "\u002f_layouts\u002f15\u002fclienttemplates.js?rev=Mfj8gPH7gaoqpkHow8ptUQ\u00253D\u00253DTAG0");</script> <script type="text/javascript">RegisterSod("sharing.js", "\u002f_layouts\u002f15\u002fsharing.js?rev=l8H6ygZ\u00252BG2\u00252BDpz6C6Y8\u00252BUg\u00253D\u00253DTAG0");RegisterSodDep("sharing.js", "strings.js");RegisterSodDep("sharing.js", "mQuery.js");RegisterSodDep("sharing.js", "clienttemplates.js");RegisterSodDep("sharing.js", "core.js");</script> <script type="text/javascript">RegisterSod("suitelinks.js", "\u002f_layouts\u002f15\u002fsuitelinks.js?rev=ShSwDRp3T8g1UhgsRv9KUg\u00253D\u00253DTAG0");RegisterSodDep("suitelinks.js", "strings.js");RegisterSodDep("suitelinks.js", "core.js");</script> <script type="text/javascript">RegisterSod("followingcommon.js", "\u002f_layouts\u002f15\u002ffollowingcommon.js?rev=QR2wCguxRV0mhBMJO0Vskw\u00253D\u00253DTAG0");RegisterSodDep("followingcommon.js", "strings.js");RegisterSodDep("followingcommon.js", "sp.js");RegisterSodDep("followingcommon.js", "userprofile");RegisterSodDep("followingcommon.js", "core.js");RegisterSodDep("followingcommon.js", "mQuery.js");</script> <script type="text/javascript">RegisterSod("profilebrowserscriptres.resx", "\u002f_layouts\u002f15\u002f1033\u002fprofilebrowserscriptres.js?rev=qwf69WaVc1mYlJLXqmZmVA\u00253D\u00253DTAG0");</script> <script type="text/javascript">RegisterSod("browserScript", "\u002f_layouts\u002f15\u002fie55up.js?rev=WNq9rt3\u00252F6kUumHFiQZo6Jw\u00253D\u00253DTAG0");RegisterSodDep("browserScript", "strings.js");</script> <script type="text/javascript">RegisterSod("inplview", "\u002f_layouts\u002f15\u002finplview.js?rev=tpT9cAwdUg7z15xrMhetGA\u00253D\u00253DTAG0");RegisterSodDep("inplview", "strings.js");RegisterSodDep("inplview", "core.js");RegisterSodDep("inplview", "clienttemplates.js");RegisterSodDep("inplview", "sp.js");</script> <script type="text/javascript">RegisterSod("dragdrop.js", "\u002f_layouts\u002f15\u002fdragdrop.js?rev=EBYmSndveb1Mkb91tDqsDA\u00253D\u00253DTAG0");RegisterSodDep("dragdrop.js", "strings.js");</script> <script type="text/javascript">RegisterSod("quicklaunch.js", "\u002f_layouts\u002f15\u002fquicklaunch.js?rev=py6pvqNpjt2nepYELtlKNQ\u00253D\u00253DTAG0");RegisterSodDep("quicklaunch.js", "strings.js");RegisterSodDep("quicklaunch.js", "dragdrop.js");</script> <script type="text/javascript">RegisterSod("WPAdderClass", "\u002f_layouts\u002f15\u002fwpadder.js?rev=529JQZgm\u00252BveAvynFOnp2OA\u00253D\u00253DTAG0");</script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/jquery.js?v=05.24.00.023"> </script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/bootstrap.bundle.min.js?v=05.24.00.023" defer="true"> </script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/jqueryui.js?v=05.24.00.023"> </script> <link type="text/xml" rel="alternate" href="/alzheimerjournal/_vti_bin/spsdisco.aspx" /> <link rel="canonical" href="https://journals.lww.com/alzheimerjournal/pages/register.aspx?ContextUrl=/alzheimerjournal/abstract/2020/01000/type_2_diabetes_interacts_with_alzheimer_disease.2.aspx" /> <noscript> <meta http-equiv="Refresh" content="3;url=/_layouts/1033/OAKS.Journals/Error/JavaScript.html" /> </noscript> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/lww-core.js?v=05.24.00.023"> </script> <script type="text/javascript" src="https://lww.com/_layouts/15/1033/Scripts/wk/journal-navigation.min.js?v=05.24.00.023" defer="true"> </script> <script type="text/javascript" src="https://lww.com/_layouts/15/1033/Scripts/wk/journals_master.min.js?v=05.24.00.023"> </script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/manifest.js?v=05.24.00.023" defer="true"> </script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/ejp.js?v=05.24.00.023" defer="true"> </script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/react-redux-vendors.js?v=05.24.00.023" defer="true"> </script> <script type="text/javascript"> var scpl_time = new Date(); scpl_time = scpl_time.getTime(); window.A8AJQ = jQuery.noConflict(); window.$ = jQuery.noConflict(); </script> <script async type="text/plain" src="https://aim-tag.hcn.health/js/client.js?dl=aimDataLayer&target=ie11" class="optanon-category-C0004"></script> <script> window.aimDataLayer = window.aimDataLayer || []; function aimTag() { aimDataLayer.push(arguments); } aimTag('2429bf11-c05b-409f-b998-8acef505546e', 'pageview'); aimTag('2429bf11-c05b-409f-b998-8acef505546e', 'signal', function (err, success) { if (err) { console.log(err); } else { console.log(success); if (success.identity_type === "AUT") { } } }); </script> </head> <body id="ctl00_BodyTag" class="lww-body ej-user-register"> <h1 id="ctl00_PageHeadingTitle" class="visually-hidden">Alzheimer Disease & Associated Disorders</h1> <span class="js-custom-event" data-config="{"name":"omni:page:view","detail":{"uid":"","uid_src":"None","page_loc":"https://journals.lww.com/alzheimerjournal/pages/register.aspx?ContextUrl=/alzheimerjournal/abstract/2020/01000/type_2_diabetes_interacts_with_alzheimer_disease.2.aspx","page_ttl":"Alzheimer Disease & Associated Disorders"},"order":2147483647,"config":{"bubbles":true,"cancelable":true,"composed":false}}"></span> <!-- Google Tag Manager (noscript) --> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-NLR6H6W"height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <!-- End Google Tag Manager (noscript) --> <div id="imgPrefetch" style="display:none"> <img src="https://cdn.wolterskluwer.io/wk-logos/1.0.x/favicon.png?rev=43" /> </div> <noscript><div class='noindex'>You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page.</div></noscript> <form method="post" action="/alzheimerjournal/pages/register.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx" onsubmit="javascript:return WebForm_OnSubmit();" id="aspnetForm"> <div class="aspNetHidden"> <input type="hidden" name="_wpcmWpid" id="_wpcmWpid" value="" /> <input type="hidden" name="wpcmVal" id="wpcmVal" value="" /> <input type="hidden" name="MSOWebPartPage_PostbackSource" id="MSOWebPartPage_PostbackSource" value="" /> <input type="hidden" name="MSOTlPn_SelectedWpId" id="MSOTlPn_SelectedWpId" value="" /> <input type="hidden" name="MSOTlPn_View" id="MSOTlPn_View" value="0" /> <input type="hidden" name="MSOTlPn_ShowSettings" id="MSOTlPn_ShowSettings" value="False" /> <input type="hidden" name="MSOGallery_SelectedLibrary" id="MSOGallery_SelectedLibrary" value="" /> <input type="hidden" name="MSOGallery_FilterString" id="MSOGallery_FilterString" value="" /> <input type="hidden" name="MSOTlPn_Button" id="MSOTlPn_Button" value="none" /> <input type="hidden" name="__EVENTTARGET" id="__EVENTTARGET" value="" /> <input type="hidden" name="__EVENTARGUMENT" id="__EVENTARGUMENT" value="" /> <input type="hidden" name="__REQUESTDIGEST" id="__REQUESTDIGEST" value="noDigest" /> <input type="hidden" name="MSOSPWebPartManager_DisplayModeName" id="MSOSPWebPartManager_DisplayModeName" value="Browse" /> <input type="hidden" name="MSOSPWebPartManager_ExitingDesignMode" id="MSOSPWebPartManager_ExitingDesignMode" value="false" /> <input type="hidden" name="MSOWebPartPage_Shared" id="MSOWebPartPage_Shared" value="" /> <input type="hidden" name="MSOLayout_LayoutChanges" id="MSOLayout_LayoutChanges" value="" /> <input type="hidden" name="MSOLayout_InDesignMode" id="MSOLayout_InDesignMode" value="" /> <input type="hidden" name="_wpSelected" id="_wpSelected" value="" /> <input type="hidden" name="_wzSelected" id="_wzSelected" value="" /> <input type="hidden" name="MSOSPWebPartManager_OldDisplayModeName" id="MSOSPWebPartManager_OldDisplayModeName" value="Browse" /> <input type="hidden" name="MSOSPWebPartManager_StartWebPartEditingName" id="MSOSPWebPartManager_StartWebPartEditingName" value="false" /> <input type="hidden" name="MSOSPWebPartManager_EndWebPartEditing" id="MSOSPWebPartManager_EndWebPartEditing" value="false" /> <input type="hidden" name="__VIEWSTATE" id="__VIEWSTATE" value="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" /> </div> <script type="text/javascript"> //<![CDATA[ var theForm = document.forms['aspnetForm']; if (!theForm) { theForm = document.aspnetForm; } function __doPostBack(eventTarget, eventArgument) { if (!theForm.onsubmit || (theForm.onsubmit() != false)) { theForm.__EVENTTARGET.value = eventTarget; theForm.__EVENTARGUMENT.value = eventArgument; theForm.submit(); } } //]]> </script> <script src="/WebResource.axd?d=dnaDAFNiQGyAS-8AAnEusSAvRcEvxsZnbowJJdr_Pi9Oz7lzs5k45FStkRo1xlEHk9NeovbY1Hwq_CwXR_md87LXDXM1L2hMpaL8ksMyAA01&t=637811513229275428" type="text/javascript"></script> <script type="text/javascript"> //<![CDATA[ var MSOWebPartPageFormName = 'aspnetForm'; var g_presenceEnabled = true; var g_wsaEnabled = false; var g_correlationId = '86ef66a1-2277-f0c3-dd35-892610de7e5e'; var g_wsaQoSEnabled = false; var g_wsaQoSDataPoints = []; var g_wsaRUMEnabled = false; var g_wsaLCID = 1033; var g_wsaListTemplateId = 850; var g_wsaSiteTemplateId = 'EJOURNALS#7'; var _spPageContextInfo={"webServerRelativeUrl":"/alzheimerjournal","webAbsoluteUrl":"https://journals.lww.com/alzheimerjournal","viewId":"","listId":"{d7dc827c-7ad0-4955-963b-ed8e6d88a88d}","listPermsMask":{"High":0,"Low":200769},"listUrl":"/alzheimerjournal/Pages","listTitle":"Pages","listBaseTemplate":850,"viewOnlyExperienceEnabled":false,"blockDownloadsExperienceEnabled":false,"idleSessionSignOutEnabled":false,"cdnPrefix":"","siteAbsoluteUrl":"https://journals.lww.com/alzheimerjournal","siteId":"{cb997674-8c63-4ae2-b44b-9f014f6286da}","showNGSCDialogForSyncOnTS":false,"supportPoundStorePath":true,"supportPercentStorePath":true,"siteSubscriptionId":null,"CustomMarkupInCalculatedFieldDisabled":true,"AllowCustomMarkupInCalculatedField":false,"isSPO":false,"farmLabel":null,"serverRequestPath":"/alzheimerjournal/pages/register.aspx","layoutsUrl":"_layouts/15","webId":"{ddc2174f-95c7-4a4d-b4ea-935c57540c9b}","webTitle":"Alzheimer Disease \u0026 Associated Disorders","webTemplate":"20200","webTemplateConfiguration":"EJOURNALS#7","webDescription":"","tenantAppVersion":"0","isAppWeb":false,"webLogoUrl":"/_layouts/images/titlegraphic.gif","webLanguage":1033,"currentLanguage":1033,"currentUICultureName":"en-US","currentCultureName":"en-US","currentCultureLCID":1033,"env":null,"nid":0,"fid":0,"serverTime":"2024-11-24T06:11:04.7752908Z","siteClientTag":"4$$16.0.10415.20001","crossDomainPhotosEnabled":false,"openInClient":false,"Has2019Era":true,"webUIVersion":15,"webPermMasks":{"High":0,"Low":196608},"pageListId":"{d7dc827c-7ad0-4955-963b-ed8e6d88a88d}","pageItemId":57,"pagePermsMask":{"High":0,"Low":200769},"pagePersonalizationScope":1,"userEmail":"","userId":0,"userLoginName":null,"userDisplayName":null,"isAnonymousUser":true,"isAnonymousGuestUser":false,"isEmailAuthenticationGuestUser":false,"isExternalGuestUser":false,"systemUserKey":null,"alertsEnabled":true,"siteServerRelativeUrl":"/alzheimerjournal","allowSilverlightPrompt":"True","themeCacheToken":"/alzheimerjournal::5:","themedCssFolderUrl":null,"themedImageFileNames":null,"modernThemingEnabled":true,"isSiteAdmin":false,"ExpFeatures":[480216468,1884350801,1158731092,62197791,538521105,335811073,4194306,34614301,268500996,-1946025984,28445328,-2147475455,134291456,65536,288,950272,1282,808326148,134217873,0,0,-1073217536,545285252,18350656,-467402752,6291457,-2147483644,1074794496,-1728053184,1845537108,622628,4102,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"killSwitches":{},"InternalValidAuthorities":["journals.na.lww.com","journals.lww.com","journals.na.lww.com","journals.lww.com","cloud-journals.lww.com","cloud-journals.lww.com"],"CorrelationId":"86ef66a1-2277-f0c3-dd35-892610de7e5e","hasManageWebPermissions":false,"isNoScriptEnabled":false,"groupId":null,"groupHasHomepage":true,"groupHasQuickLaunchConversationsLink":false,"departmentId":null,"hubSiteId":null,"hasPendingWebTemplateExtension":false,"isHubSite":false,"isWebWelcomePage":false,"siteClassification":"","hideSyncButtonOnODB":false,"showNGSCDialogForSyncOnODB":false,"sitePagesEnabled":false,"sitePagesFeatureVersion":0,"DesignPackageId":"00000000-0000-0000-0000-000000000000","groupType":null,"groupColor":"#757575","siteColor":"#757575","headerEmphasis":0,"navigationInfo":null,"guestsEnabled":false,"MenuData":{"SignInUrl":"/alzheimerjournal/_layouts/15/Authenticate.aspx?Source=%2Falzheimerjournal%2Fpages%2Fregister%2Easpx%3FContextUrl%3D%252Falzheimerjournal%252Fabstract%252F2020%252F01000%252Ftype%255F2%255Fdiabetes%255Finteracts%255Fwith%255Falzheimer%255Fdisease%252E2%252Easpx"},"RecycleBinItemCount":-1,"PublishingFeatureOn":true,"PreviewFeaturesEnabled":false,"disableAppViews":false,"disableFlows":false,"serverRedirectedUrl":null,"formDigestValue":"0x3812B9B97ECDDBFD0E78639B516E10E1A50704928064F5AD2D07F3CB0404B270268059DA4BA1FA1020387ECD9B1D305CB1674B918A412BF9B446739A50F0CF61,24 Nov 2024 06:11:04 -0000","maximumFileSize":10240,"formDigestTimeoutSeconds":1800,"canUserCreateMicrosoftForm":false,"canUserCreateVisioDrawing":true,"readOnlyState":null,"isTenantDevSite":false,"preferUserTimeZone":false,"userTimeZoneData":null,"userTime24":false,"userFirstDayOfWeek":null,"webTimeZoneData":null,"webTime24":false,"webFirstDayOfWeek":null,"isSelfServiceSiteCreationEnabled":null,"alternateWebAppHost":"","aadTenantId":"","aadUserId":"","aadInstanceUrl":"","msGraphEndpointUrl":"https://","allowInfectedDownload":true};_spPageContextInfo.updateFormDigestPageLoaded=new Date();_spPageContextInfo.clientServerTimeDelta=new Date(_spPageContextInfo.serverTime)-new Date();if(typeof(define)=='function'){define('SPPageContextInfo',[],function(){return _spPageContextInfo;});}var L_Menu_BaseUrl="/alzheimerjournal"; var L_Menu_LCID="1033"; var L_Menu_SiteTheme="null"; document.onreadystatechange=fnRemoveAllStatus; function fnRemoveAllStatus(){removeAllStatus(true)};//]]> </script> <script src="https://lww.com/_layouts/15/1033/Scripts/wk/alerts-subscription.min.js?v=05.24.00.023" type="text/javascript"></script> <script type="text/javascript"> //<![CDATA[ Flighting.ExpFeatures = [480216468,1884350801,1158731092,62197791,538521105,335811073,4194306,34614301,268500996,-1946025984,28445328,-2147475455,134291456,65536,288,950272,1282,808326148,134217873,0,0,-1073217536,545285252,18350656,-467402752,6291457,-2147483644,1074794496,-1728053184,1845537108,622628,4102,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]; (function() { if(typeof(window.SP) == "undefined") window.SP = {}; if(typeof(window.SP.YammerSwitch) == "undefined") window.SP.YammerSwitch = {}; var ysObj = window.SP.YammerSwitch; ysObj.IsEnabled = false; ysObj.TargetYammerHostName = "www.yammer.com"; } )(); var _spWebPartComponents = new Object();//]]> </script> <script src="/ScriptResource.axd?d=11ySqNT2t8wJXf-5ynqkHTYVaR0CZPUQDLhFk5-B61-yY4pHK9T4A-OmNoLERHX1OU2F3io32lKHXeNlvH0kpnJP6-ZQm2Ado5OlvNqUwB9TpwuIgMVQBgIz-DSVpHWqDoVFHrt69C9fSrbhF6t9QBuuAcSpa-p9_2de4EnR0aU1&t=2265eaa7" type="text/javascript"></script> <script src="/_layouts/15/blank.js?rev=6Epdi%2BEh0XOHrFNRcf4Cwg%3D%3DTAG0" type="text/javascript"></script> <script type="text/javascript"> //<![CDATA[ window.SPThemeUtils && SPThemeUtils.RegisterCssReferences([]); (function(){ if (typeof(_spBodyOnLoadFunctions) === 'undefined' || _spBodyOnLoadFunctions === null) { return; } _spBodyOnLoadFunctions.push(function() { SP.SOD.executeFunc('core.js', 'FollowingDocument', function() { FollowingDocument(); }); }); })();(function(){ if (typeof(_spBodyOnLoadFunctions) === 'undefined' || _spBodyOnLoadFunctions === null) { return; } _spBodyOnLoadFunctions.push(function() { SP.SOD.executeFunc('core.js', 'FollowingCallout', function() { FollowingCallout(); }); }); })();if (typeof(DeferWebFormInitCallback) == 'function') DeferWebFormInitCallback();function WebForm_OnSubmit() { UpdateFormDigest('\u002falzheimerjournal', 1440000);if (typeof(ValidatorOnSubmit) == "function" && ValidatorOnSubmit() == false) return false;if (typeof(_spFormOnSubmitWrapper) != 'undefined') {return _spFormOnSubmitWrapper();} else {return true;}; return true; } //]]> </script> <div class="aspNetHidden"> <input type="hidden" name="__VIEWSTATEGENERATOR" id="__VIEWSTATEGENERATOR" value="1897E141" /> <input type="hidden" name="__EVENTVALIDATION" id="__EVENTVALIDATION" value="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" /> </div> <script type="text/javascript"> var submitHook = function () { return false; }; theForm._spOldSubmit = theForm.submit; theForm.submit = function () { if (!submitHook()) { this._spOldSubmit(); } }; </script> <span id="DeltaSPWebPartManager"> </span> <script type="text/javascript">$.getJSON("https://login.journals.lww.com/AuthCheck.aspx?Callback=?", null, function (data) { if(data.IsAuthenticated.toLowerCase() == "true") {window.location.replace("https://login.journals.lww.com/?wa=wsignin1.0&wtrealm=urn%3ajournals&wctx=https%3a%2f%2fjournals.lww.com%2falzheimerjournal%2f_layouts%2f15%2fAuthenticate.aspx%3fSource%3d%252falzheimerjournal%252fabstract%252f2020%252f01000%252ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx"); } }) </script> <script type="text/javascript"> //<![CDATA[ Sys.WebForms.PageRequestManager._initialize('ctl00$ScriptManager', 'aspnetForm', ['fctl00$WebPartAdderUpdatePanel',''], [], ['ctl00$WebPartAdder',''], 90, 'ctl00'); //]]> </script> <span id="DeltaDelegateControls"> </span> <!-- start ( this can all go into PublishingSiteAction:SiteActionMenu )---> <!-- end ( this can all go into PublishingSiteAction:SiteActionMenu )---> <div class="ejp-corporate-hat"> <div class="ejp-corporate-hat__content wk-grid-page-container"> <a href="https://lww.com/pages/default.aspx"> <div role="img" class="ejp-corporate-hat__logo ejp-corporate-hat__logo--lww" aria-label="Lippincott Logo"></div> </a> </div> </div> <div id="ctl00_MicrobarContainer" class="top-microbar-container"> </div> <!-- Header Banners delegate control --> <a id="HiddenAnchor" href="javascript:;" style="display: none;"></a> <!-- Header Advertisements delegate control --> <div id="ctl00_TopAdvertisementContainer" class="advertisement-content_top top-banner"> <div class="top-banner__content--centered top-banner--low-opacity"> <div id="ctl00_ctl49_adContainer" class="ej-advertisement ej-advertisement-topcombo"> <div class="ej-advertisement-content"> <div> <div id="ga_23043f7c-a431-4d84-9b14-86084c737d61" class="ad-slot-container ad-slot-container-ga_23043f7c-a431-4d84-9b14-86084c737d61" data-sizemap="[[[730, 500], [[728, 90]]], [[0, 0], [[300, 50]]]]" data-adpath="/15726702761/Desktop/alzheimerjournal/Other/Top" data-autoload="yes" data-outofpage="no" data-sticky="yes" data-slottargeting='' data-displayslug="yes" data-sticky-duration="5" data-name="Top"></div> </div> </div> </div> </div> </div> <div class="main-wrapper"> <div id="main-container"> <!-- Header delegate control --> <header class="header"> <div class="header__holder"> <div class="header__layout-top no-logo wk-grid-page-container"> <script type="text/javascript" src="https://lww.com/_layouts/15/1033/Scripts/wk/UserToolbarDropdown.js?v=05.24.00.023" defer="true"> </script> <section class="user-action-toolbar"> <ul class="user-menu user-info" role="tablist"> <li id="ctl00_ctl51_Header_UserActionTools_liLogin" class="user-menu__item user-menu__item--popup-container user-menu__item--login-popup-container dib"> <button class="user-menu__link user-menu__link--login js-ejp-login-btn" type="button" data-config="{"eventName":"login","eventDetail":{"source":"Masthead Dropdown"},"isNull":false}"> <i class="fa fa-sign-in"></i> <span>Log in</span> </button> </li> <li id="ctl00_ctl51_Header_UserActionTools_liOr" class="dib or-spacing"><span>or</span></li> <li id="ctl00_ctl51_Header_UserActionTools_liRegister2" class="user-menu__item dib"> <a id="ctl00_ctl51_Header_UserActionTools_RegisterUserPopupLnk" class="user-menu__link js-register-link" data-config="{"eventName":"Register","eventDetail":{"source":"Masthead Dropdown"},"isNull":false}" href="https://journals.lww.com/alzheimerjournal/pages/register.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx">Register</a> </li> <li id="ctl00_ctl51_Header_UserActionTools_liSubscribe" role="presentation" class="user-menu__item dib"> <a id="ctl00_ctl51_Header_UserActionTools_lnkSubscribe" class="user-menu__link" href="https://shop.lww.com/p/0893-0341" target="_blank"><i class="fa fa-bars"></i> <span class="hideOnFixed">Subscribe to journal</span><span class="showOnFixed">Subscribe</span></a> </li> <li id="ctl00_ctl51_Header_UserActionTools_liIssueAlerts" class="user-menu__item dib"> <i class="fa fa-envelope"></i> <a rel="nofollow" title href="javascript:javascript: alerts_ShowSubscribeeTOCPopup('Alzheimer Disease & Associated Disorders','alzheimerjournal','eTOC', 'eTOC');;" onclick="javascript: alerts_ShowSubscribeeTOCPopup('Alzheimer Disease & Associated Disorders','alzheimerjournal','eTOC', 'eTOC');" class="user-menu__link"><span id="ctl00_ctl51_Header_UserActionTools_SubscribeToAlertsActionToolLink_defaultText" class="hideOnFixed">Get new issue alerts</span><span id="ctl00_ctl51_Header_UserActionTools_SubscribeToAlertsActionToolLink_stickyText" class="showOnFixed">Get alerts</span></a> </li> </ul> </section> <span id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_dummyTargetControl"></span> <div id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pnlunSubscribeToAlerts" style="display: none;"> <div tabindex="-1" role="dialog" class="wk-modal horizontally-centered small wk-modal-with-overlay wk-modal-small ejp-modal"> <div id="ej-box-modal-style-1"> <div id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pnlMain"> <div id="tocUnsubscribeModal" > <section class="wk-modal-content"> <header class="wk-modal-header ejp-modal-header"> <div class="wk-modal-title ejp-modal-title"></div> <button aria-label="close dialog" class="js-close primary-button wk-button-icon wk-modal-close ejp-modal-close "><i class="fa fa-times"></i></button> </header> <div class="wk-modal-body"> <div class="wk-field-item"> <p> <span id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_lblUnsubscribeMessage"></span> </p> <div class="wk-button-bar"> <div class="wk-button-group-left"> <p id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pUnsubscribeButtons" Style="display: none;"> <input type="submit" name="ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$btnContinue" value="Yes" onclick="javascript:WebForm_DoPostBackWithOptions(new WebForm_PostBackOptions("ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$btnContinue", "", true, "", "", false, false))" id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_btnContinue" class="primary-button" /> <input type="button" value="No" id="btnCancel" aria-label="close dialog" class="js-close secondary-button" /> </p> </div> </div> </div> </div> </section> </div> </div> </div> </div> </div> <div id="ej-clear-float"> </div> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$hiddenUnSubscribeAlertType" id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnSubscribeAlertType" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$hiddenUnsubscribeJournalId" id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeJournalId" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$hiddenUnsubscribeMessage" id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeMessage" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$hiddenTopicalCollectionId" id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenTopicalCollectionId" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$hiddenOvidId" id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenOvidId" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$ucUnsubscribeToAlertsUserControl$hiddenJournalId" id="ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenJournalId" /> <script type="text/javascript"> function alerts_ShowUnSubscribeeTOCPopup(title, alertType, journalId) { var unSubscribeeTocPopup = $find('unSubscribeToAlerts'); var lblUnsubscribeMessage = document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_lblUnsubscribeMessage'); lblUnsubscribeMessage.innerHTML = title; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnSubscribeAlertType').value = alertType; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeMessage').value = title; $('#' + 'ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pUnsubscribeButtons').show(); if (document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenJournalId').value == null || document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenJournalId').value == '') { document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenJournalId').value = journalId; } if (unSubscribeeTocPopup != null) { unSubscribeeTocPopup.show(); } } function alerts_ShowUnSubscribeeTOCPopup_Root(title, journalId, alertType) { var unSubscribeeTocPopup = $find('unSubscribeToAlerts'); var lblUnsubscribeMessage = document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_lblUnsubscribeMessage'); lblUnsubscribeMessage.innerHTML = title; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeMessage').value = title; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnSubscribeAlertType').value = alertType; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeJournalId').value = journalId; $('#' + 'ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pUnsubscribeButtons').show(); if (unSubscribeeTocPopup != null) { unSubscribeeTocPopup.show(); } } function alerts_ShowUnSubscribeeTOCPopup_Citation(title, journalId, ovidId) { var unSubscribeeTocPopup = $find('unSubscribeToAlerts'); var lblUnsubscribeMessage = document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_lblUnsubscribeMessage'); lblUnsubscribeMessage.innerHTML = title; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeMessage').value = title; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnSubscribeAlertType').value = 'Citation'; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeJournalId').value = journalId; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenOvidId').value = ovidId; $('#' + 'ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pUnsubscribeButtons').show(); if (unSubscribeeTocPopup != null) { unSubscribeeTocPopup.show(); } } function alerts_ShowUnSubscribeeTOCPopup_Topical(title, journalId, topicalCollectionId) { var unSubscribeeTocPopup = $find('unSubscribeToAlerts'); var lblUnsubscribeMessage = document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_lblUnsubscribeMessage'); lblUnsubscribeMessage.innerHTML = title; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeMessage').value = title; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnSubscribeAlertType').value = 'Topical'; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenUnsubscribeJournalId').value = journalId; document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenTopicalCollectionId').value = topicalCollectionId; $('#' + 'ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pUnsubscribeButtons').show(); if (document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenJournalId').value == null || document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenJournalId').value == '') { document.getElementById('ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_hiddenJournalId').value = journalId; } if (unSubscribeeTocPopup != null) { unSubscribeeTocPopup.show(); } } function alerts_ShowUnSubscribeeTOCSuccessPopup() { var unSubscribeeTocPopup = $find('unSubscribeToAlerts'); if (unSubscribeeTocPopup != null) { unSubscribeeTocPopup.show(); } } $('.js-close').on('click', function() { var unSubscribeeTocPopup = $find('unSubscribeToAlerts'); if (unSubscribeeTocPopup != null) { unSubscribeeTocPopup.hide(); } return false; }); </script> <span id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_dummyTargetControl"></span> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$SubscribeToEtocPopupControl$hiddenSubscribeToEtocPopupState" id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenSubscribeToEtocPopupState" value="showemail" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$SubscribeToEtocPopupControl$hiddenConfirmSubscriptionPageUrl" id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenConfirmSubscriptionPageUrl" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$SubscribeToEtocPopupControl$hiddenJournalId" id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenJournalId" /> <input type="hidden" name="ctl00$ctl51$Header$UserActionTools$SubscribeToEtocPopupControl$hiddenSubscriptionType" id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenSubscriptionType" /> <div id="divPopupOverLay" class="Popup-Overlay" style="display: none; position: fixed; left: 0; top: 0; z-index: 3800; width: 1920px; height: 4517px;"></div> <div id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_pnlSubscribeToEtoc" class="etoc-popup ej-box-modal-drop-shadow" style="display: none;"> <div tabindex="-1" role="dialog" class="wk-modal horizontally-centered small wk-modal-with-overlay wk-modal-small ejp-modal"> <div id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_pnlMain" onkeypress="javascript:return WebForm_FireDefaultButton(event, 'ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_btnContinue')"> <section class="wk-modal-content"> <header class="wk-modal-header ejp-modal-header"> <div class="wk-modal-title ejp-modal-title"> <span id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_lblTitle"></span> </div> <button aria-label="close dialog" class="js-close primary-button wk-button-icon wk-modal-close ejp-modal-close "> <i class="fa fa-times"></i> </button> </header> <div class="wk-modal-body"> <div class="wk-field-item"> <div class="wk-field-body"> <strong> <span id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_lblThankYouMessage"></span></strong> </div> <div class="wk-field-body"> <span id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError" style="color:Black;display:none;"> <div class="ej-error-message"> <p class="ej-error-message-icon error-red"> </p> </div> </span> <label for="Email input">Enter your Email address:</label> <div class="wk-field-body"> <input name="ctl00$ctl51$Header$UserActionTools$SubscribeToEtocPopupControl$txtEmailAddress" type="text" id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_txtEmailAddress" class="ej-box-modal-style-1-input" /> </div> </div> <div class="wk-button-bar"> <div class="wk-button-group-left"> <input type="submit" name="ctl00$ctl51$Header$UserActionTools$SubscribeToEtocPopupControl$btnContinue" value="Continue" onclick="javascript:WebForm_DoPostBackWithOptions(new WebForm_PostBackOptions("ctl00$ctl51$Header$UserActionTools$SubscribeToEtocPopupControl$btnContinue", "", true, "", "", false, false))" id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_btnContinue" class="primary-button" /> <input type="button" value="Cancel" id="btnCancel" class="js-close secondary-button" /> </div> </div> </div> <div class="wk-field-item"> <div class="wk-field-body"> <a id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hypPrivacy" href="https://journals.lww.com/alzheimerjournal/_layouts/oaks.journals/privacy.aspx" target="_blank">Privacy Policy</a> </div> </div> </div> </section> </div> <div id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_pnlAuthenticatedUser" style="display: none;"> <section class="wk-modal-content"> <header class="wk-modal-header ejp-modal-header"> <div class="wk-modal-title ejp-modal-title"></div> <button aria-label="close dialog" class="js-close primary-button wk-button-icon wk-modal-close ejp-modal-close "><i class="fa fa-times"></i></button> </header> <div class="wk-modal-body"> <div class="wk-field-item"> <p> <strong> <span id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_lblAuthenticatedUserTitle"></span> </strong> </p> </div> <p id="ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_pAuthenticatedUserMessage"> </p> </div> </section> </div> </div> </div> <div id="ej-clear-float"> </div> <script type="text/javascript"> function alerts_SaveSubscriptionTypeInHiddenField(url, subscriptionType, journalId, yearId, issueId, articleId) { if (journalId && yearId && issueId && articleId) { logCounterDataAlertWhenCitedSynchronously(journalId, yearId, issueId, articleId); } $('#' + 'ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenSubscriptionType').val(subscriptionType); $('#' + 'ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenJournalId').val(journalId); if (url) window.location = url; else __doPostBack('hypSubscribeToAlerts'); return false; } function alerts_ShowSubscribeeTOCPopup(journalTitle, journalId, subscriptionType, displaySubscriptionType) { $('#' + 'ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenSubscriptionType').val(subscriptionType); var subscribeToEtocPopup = $find('subscribeToEtoc'); subscribeToEtocPopup.show(); document.getElementsByTagName( 'html' )[0].classList.add('no-scroll'); var modelPopupState = document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenSubscribeToEtocPopupState'); var emailTextBox = document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_txtEmailAddress'); var thanksPanel = document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_pnlAuthenticatedUser'); var mainPanel = document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_pnlMain'); var thankYouMessageUnAuthenticated = document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_lblThankYouMessage'); var thankYouMessageAuthenticated = document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_lblAuthenticatedUserTitle'); if (!displaySubscriptionType) { displaySubscriptionType = subscriptionType; } if (modelPopupState.value == 'showthanksmessage') { thanksPanel.style.display = "block"; mainPanel.style.display = "none"; thankYouMessageAuthenticated.innerHTML = "Thank you for subscribing to the " + displaySubscriptionType + " for " + journalTitle + "."; } if (modelPopupState.value == 'showemail') { thanksPanel.style.display = "none"; mainPanel.style.display = "block"; thankYouMessageUnAuthenticated.innerHTML = "Thank you for choosing to subscribe to the " + displaySubscriptionType + " for " + journalTitle + "."; } if ($('.etoc-popup') != null) { document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenJournalId').value = journalId; if (modelPopupState.value == 'showemail') emailTextBox.focus(); } } $('.js-close').on('click', function () { document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_txtEmailAddress').value = ""; document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError').style.display = "none"; var pageUrl = document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_hiddenConfirmSubscriptionPageUrl'); var subscribeeTocPopup = $find('subscribeToEtoc'); if (subscribeeTocPopup != null) { subscribeeTocPopup.hide(); document.getElementsByTagName( 'html' )[0].classList.remove('no-scroll'); if (pageUrl.value !== '' && pageUrl.value !== window.location.pathname) window.location = pageUrl.value; } return false; }); </script> <div id="ctl00_ctl51_Header_UserActionTools_eTocTopContainer"> <div id="eTocTop" style="display: none;"> <a rel="nofollow" title href="javascript:javascript: alerts_ShowSubscribeeTOCPopup('Alzheimer Disease & Associated Disorders','alzheimerjournal','eTOC', 'eTOC');;" onclick="javascript: alerts_ShowSubscribeeTOCPopup('Alzheimer Disease & Associated Disorders','alzheimerjournal','eTOC', 'eTOC');"><span id="ctl00_ctl51_Header_UserActionTools_alertLinkControlTop_defaultText" class="hideOnFixed">Subscribe to eTOC</span></a> </div> </div> <script> $(function () { //find recent searches link and move container var recentSearchesControl = $("a[id$='RecentSearches']"); if (recentSearchesControl.length) { recentSearchesControl.click(function (e) { e.stopPropagation(); if ($("#ResentSearchContainer").is(":hidden")) { $("#ResentSearchContainer").slideDown("slow"); recentSearchesControl.addClass('open'); } else { $("#ResentSearchContainer").hide(); recentSearchesControl.removeClass('open'); } }); } var eTocAccountLink = $("ul.js-user-action-toolbar__dropdown>li>a[id='SubscribeToEToc']"); if (eTocAccountLink.length) { eTocAccountLink.parent().html($("#eTocTop>a")); } }); </script> <a class="logo-secondary" href="" target="_blank"> <h3 class="logo-secondary-text">Secondary Logo</h3> </a> <a href="#" class="sticky-search"><i class="fa fa-search"></i></a> </div> <div class="header__layout-bottom wk-grid-page-container"> <a id="hypJournals" class="logo-main" href="https://journals.lww.com/alzheimerjournal/pages/default.aspx"> <h3 class="logo-main-text">Journal Logo </h3> </a> <div class="search-v2"> <div class="search-wrapper"> <select name="ctl00$ctl51$Header$SearchTopBoxControl$ddlContentScope" id="ctl00_ctl51_Header_SearchTopBoxControl_ddlContentScope"> <option value="All">All</option> <option selected="selected" value="Articles">Articles</option> <option value="Images">Images</option> <option value="Videos">Videos</option> <option value="Podcasts">Podcasts</option> <option value="Blogs">Blogs</option> </select> <div class="input-group" id="globalSearch"> <input name="ctl00$ctl51$Header$SearchTopBoxControl$txtKeywords" type="text" value="Search" id="ctl00_ctl51_Header_SearchTopBoxControl_txtKeywords" class="form-control searchText" /> <span class="input-group-btn"> <button id="ctl00_ctl51_Header_SearchTopBoxControl_btnGlobalSearchMagnifier" type="submit" class="btn btn-default"><i class="fa fa-search"></i></button> </span> <input type="hidden" name="ctl00$ctl51$Header$SearchTopBoxControl$IsAutoCompleteEnabled" id="ctl00_ctl51_Header_SearchTopBoxControl_IsAutoCompleteEnabled" value="true" /> <input type="hidden" name="ctl00$ctl51$Header$SearchTopBoxControl$AutocompleteApiUrl" id="ctl00_ctl51_Header_SearchTopBoxControl_AutocompleteApiUrl" value="https://platformservices.wolterskluwerhealth.com/autocomplete/ALDAD/shingle/" /> </div> </div> <div class="advance-search" style=""> <a id="ctl00_ctl51_Header_SearchTopBoxControl_lnkAdvanceSearch" href="https://journals.lww.com/alzheimerjournal/pages/advancedsearch.aspx">Advanced Search</a> <input type="submit" name="ctl00$ctl51$Header$SearchTopBoxControl$btnGlobalSearch" value="" id="ctl00_ctl51_Header_SearchTopBoxControl_btnGlobalSearch" disabled="disabled" class="aspNetDisabled btnGlobalSearch" style="display: none;" /> <input name="ctl00$ctl51$Header$SearchTopBoxControl$hfldKeywords" type="hidden" id="ctl00_ctl51_Header_SearchTopBoxControl_hfldKeywords" class="hfldKeywords" value="disableButton" /> </div> </div> <script> $(function() { try { var objSearchBox = { btnGlobalSearchMagnifierId: 'ctl00_ctl51_Header_SearchTopBoxControl_btnGlobalSearchMagnifier', searchButtonId: 'ctl00_ctl51_Header_SearchTopBoxControl_btnGlobalSearch', txtKeywordsId: 'ctl00_ctl51_Header_SearchTopBoxControl_txtKeywords', hfldKeywordsHiddenId: 'ctl00_ctl51_Header_SearchTopBoxControl_hfldKeywords', defaultSearchText: 'Search' }; new Searchbox(objSearchBox).Init(); } catch (e) { console.error(e); } }); //autocomplete functionality for basic search //this functionality will call the SBA url and start suggesting after typing 3rd character var textKeywords = null; var hiddenAutocompleteApiUrl = null; var buttonGlobalSearch = null; $(function () { try { var objAutocomplete = { hiddenIsAutoCompleteEnabled: $('#ctl00_ctl51_Header_SearchTopBoxControl_IsAutoCompleteEnabled'), textKeywords: $('#ctl00_ctl51_Header_SearchTopBoxControl_txtKeywords'), hiddenAutocompleteApiUrl: $('#ctl00_ctl51_Header_SearchTopBoxControl_AutocompleteApiUrl'), buttonGlobalSearch: $('#ctl00_ctl51_Header_SearchTopBoxControl_btnGlobalSearch'), enableNewAutoComplete: true, newAutoCompleteUrl: 'https://dxg-search-na-prd.wkgposvc.cloud/Query.svc/Query_Expand', newAutoCompleteMaxSuggestions: '10', newAutoCompleteDictionaryIds: 'ovid_sted28_mesh22' }; autoComplete(objAutocomplete); } catch (e) { console.error(e); } }); $(function () { let searchSelect = $('select[id$="ddlContentScope"]');; if (searchSelect.length){ searchSelect.selectize(); } }); </script> </div> <div id="main-nav-container-v2"> <nav id="main-nav" class="navbar navbar-default yamm wk-grid-page-container"> <div class="navbar-header"> <button id="fatJuicy" type="button" class="navbar-hamburger-button navbar-toggle collapsed pull-left" data-bs-toggle="collapse" data-bs-target="#zz1_TopNavigationMenu" aria-expanded="false" aria-controls="navbar"> <span class="visually-hidden">Toggle navigation</span> <span class="icon-bar"></span> <span class="icon-bar"></span> <span class="icon-bar"></span> <span class="navbar-hamburger-button__text"></span> </button> </div> <div id="navActionButtons" class="btn-group navbar-hover-color" role="group" aria-label="..."> <a id="ctl00_ctl51_lnkSubscribe" class="btn btn-default navbar-button" href="https://shop.lww.com/p/0893-0341" target="_blank">Subscribe</a> <a id="ctl00_ctl51_lnkRegister" class="btn btn-default navbar-button" href="https://journals.lww.com/alzheimerjournal/pages/register.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx">Register</a> <button class="user-menu__link user-menu__link--login js-ejp-login-btn btn btn-default navbar-button" type="button" data-config="{"eventName":"login","eventDetail":{},"isNull":false}"> <span>Login</span> </button> </div> <div id="ctl00_ctl51_TopNavigationMenuConfiguration" style="display:none" class="js-top-navigation-menu-configuration" data-config="{"browsingHistory":{"isEnabled":true,"serviceUrl":"https://apim-hlrp-ejp-prod.azure-api.net/ee","pdfDownloadUrl":"/_layouts/15/oaks.journals/downloadpdf.aspx?trckng_src_pg=HistoryTab"}}"></div> <div id="zz1_TopNavigationMenu" class="navbar-collapse collapse js-top-navigation-menu noindex ms-core-listMenu-horizontalBox"> <ul id="zz2_RootAspMenu" class="root ms-core-listMenu-root static"> <li class="static dynamic-children"><span class="static dynamic-children menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode"><span aria-haspopup="true" class="additional-background ms-navedit-flyoutArrow dynamic-children"><span class="menu-item-text">Articles & Issues</span></span></span><ul aria-hidden="true" class="dynamic"> <li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Pages/currenttoc.aspx" accesskey="1"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Current Issue</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Pages/issuelist.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Previous Issues</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/toc/publishahead"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Published Ahead-of-Print</span></span></a></li> </ul></li><li class="static dynamic-children"><span class="static dynamic-children menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode"><span aria-haspopup="true" class="additional-background ms-navedit-flyoutArrow dynamic-children"><span class="menu-item-text">Edici贸n en espa帽ol</span></span></span><ul aria-hidden="true" class="dynamic"> <li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma_Argentina_Alzheimer Disease_Issue 1_PDF_2014.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 1 - 2014</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma_Argentina_Alzheimer Disease_Issue 3_PDF_2014.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 3 - 2014</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma_Argentina_Alzheimer Disease_Issue 1_PDF_2015.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 1 - 2015</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma_Argentina_Alzheimer Disease_Issue 2_PDF_2015.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 2 - 2015</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma/Consult Pharma_Argentina_Alzheimer Disease_Issue 3_PDF_2015.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 3 - 2015</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma/Consult Pharma_Argentina_Alzheimer Disease_Issue 1_PDF_2016.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 1 - 2016</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma/Consult Pharma_Argentina_Alzheimer Disease_Issue 2_PDF_2016.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 2 - 2016</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma/Consult Pharma_Argentina_Alzheimer Disease_Issue 3_PDF_2016.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 3 - 2016</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Documents/Consult Pharma/Consult Pharma_Argentina_Alzheimer Disease_Issue 4_PDF_2016.pdf"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Issue 4 - 2016</span></span></a></li> </ul></li><li class="static"><a class="static menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Pages/collections.aspx?Collection=Topical"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Collections</span></span></a></li><li class="static dynamic-children"><span class="static dynamic-children menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode"><span aria-haspopup="true" class="additional-background ms-navedit-flyoutArrow dynamic-children"><span class="menu-item-text">For Authors</span></span></span><ul aria-hidden="true" class="dynamic"> <li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="https://preflight.paperpal.com/partner/lww/alzheimerdisassociateddisorders/submit"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Submit a Manuscript</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="https://journals.lww.com/alzheimerjournal/Pages/informationforauthors.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Information for Authors</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/_layouts/1033/oaks.journals/editservices.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Language Editing Services</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="https://cdn-tp2.mozu.com/16833-m1/cms/files/Author-Document.pdf?_mzts=636519775710000000"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Author Permissions</span></span></a></li> </ul></li><li class="static dynamic-children"><span class="static dynamic-children menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode"><span aria-haspopup="true" class="additional-background ms-navedit-flyoutArrow dynamic-children"><span class="menu-item-text">Journal Info</span></span></span><ul aria-hidden="true" class="dynamic"> <li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Pages/aboutthejournal.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">About the Journal</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/Pages/editorialboard.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Editorial Board</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="https://www.wolterskluwer.com/en/solutions/lippincott-audience-solutions/media-kits/alzheimer-disease-and-associated-disorders"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Advertising</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="http://www.wkopenhealth.com/"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Open Access</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/_layouts/1033/oaks.journals/subscriptionservices.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Subscription Services</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/_layouts/1033/oaks.journals/reprintsmedicine.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Reprints</span></span></a></li><li class="dynamic"><a class="dynamic menu-item ms-core-listMenu-item ms-displayInline ms-navedit-linkNode" href="/alzheimerjournal/_layouts/1033/oaks.journals/rightsandpermissions.aspx"><span class="additional-background ms-navedit-flyoutArrow"><span class="menu-item-text">Rights and Permissions</span></span></a></li> </ul></li> </ul> </div> <div class="search-v2"> <div class="search-wrapper"> <select name="ctl00$ctl51$SearchBox$ddlContentScope" id="ctl00_ctl51_SearchBox_ddlContentScope"> <option value="All">All</option> <option selected="selected" value="Articles">Articles</option> <option value="Images">Images</option> <option value="Videos">Videos</option> <option value="Podcasts">Podcasts</option> <option value="Blogs">Blogs</option> </select> <div class="input-group" id="globalSearch"> <input name="ctl00$ctl51$SearchBox$txtKeywords" type="text" value="Search" id="ctl00_ctl51_SearchBox_txtKeywords" class="form-control searchText" /> <span class="input-group-btn"> <button id="ctl00_ctl51_SearchBox_btnGlobalSearchMagnifier" type="submit" class="btn btn-default"><i class="fa fa-search"></i></button> </span> <input type="hidden" name="ctl00$ctl51$SearchBox$IsAutoCompleteEnabled" id="ctl00_ctl51_SearchBox_IsAutoCompleteEnabled" value="true" /> <input type="hidden" name="ctl00$ctl51$SearchBox$AutocompleteApiUrl" id="ctl00_ctl51_SearchBox_AutocompleteApiUrl" value="https://platformservices.wolterskluwerhealth.com/autocomplete/ALDAD/shingle/" /> </div> </div> <div class="advance-search" style=""> <a id="ctl00_ctl51_SearchBox_lnkAdvanceSearch" href="https://journals.lww.com/alzheimerjournal/pages/advancedsearch.aspx">Advanced Search</a> <input type="submit" name="ctl00$ctl51$SearchBox$btnGlobalSearch" value="" id="ctl00_ctl51_SearchBox_btnGlobalSearch" disabled="disabled" class="aspNetDisabled btnGlobalSearch" style="display: none;" /> <input name="ctl00$ctl51$SearchBox$hfldKeywords" type="hidden" id="ctl00_ctl51_SearchBox_hfldKeywords" class="hfldKeywords" value="disableButton" /> </div> </div> <script> $(function() { try { var objSearchBox = { btnGlobalSearchMagnifierId: 'ctl00_ctl51_SearchBox_btnGlobalSearchMagnifier', searchButtonId: 'ctl00_ctl51_SearchBox_btnGlobalSearch', txtKeywordsId: 'ctl00_ctl51_SearchBox_txtKeywords', hfldKeywordsHiddenId: 'ctl00_ctl51_SearchBox_hfldKeywords', defaultSearchText: 'Search' }; new Searchbox(objSearchBox).Init(); } catch (e) { console.error(e); } }); //autocomplete functionality for basic search //this functionality will call the SBA url and start suggesting after typing 3rd character var textKeywords = null; var hiddenAutocompleteApiUrl = null; var buttonGlobalSearch = null; $(function () { try { var objAutocomplete = { hiddenIsAutoCompleteEnabled: $('#ctl00_ctl51_SearchBox_IsAutoCompleteEnabled'), textKeywords: $('#ctl00_ctl51_SearchBox_txtKeywords'), hiddenAutocompleteApiUrl: $('#ctl00_ctl51_SearchBox_AutocompleteApiUrl'), buttonGlobalSearch: $('#ctl00_ctl51_SearchBox_btnGlobalSearch'), enableNewAutoComplete: true, newAutoCompleteUrl: 'https://dxg-search-na-prd.wkgposvc.cloud/Query.svc/Query_Expand', newAutoCompleteMaxSuggestions: '10', newAutoCompleteDictionaryIds: 'ovid_sted28_mesh22' }; autoComplete(objAutocomplete); } catch (e) { console.error(e); } }); $(function () { let searchSelect = $('select[id$="ddlContentScope"]');; if (searchSelect.length){ searchSelect.selectize(); } }); </script> </nav> </div> </div> </header> <!-- topbanner start --> <!-- topbanner start --> <!-- topbanner end --> <!-- topbanner end --> <div id="main-container-content" class="wk-grid-page-container"> <div id="DeltaWebPartAdderUpdatePanelContainer" class="ms-core-webpartadder"> <div id="WebPartAdderUpdatePanelContainer"> <div id="ctl00_WebPartAdderUpdatePanel"> <span id="ctl00_WebPartAdder"></span> </div> </div> </div> <div id="notificationArea" class="ms-notif-box"></div> <div id="DeltaPageStatusBar"> <div id="pageStatusBar"></div> </div> <div id="DeltaPlaceHolderMain" class="delta-place-holder-main"> <a id="mainContent" name="mainContent" tabindex="-1"></a> <DIV class="main-content"><div id="ctl00_PlaceHolderMain_ctl00_ctl01_row" class="dpl-row" data-dpl-row-id="448200B9D1AE4E3BA8CC301925D9" data-dpl-default-tag-name="div"> <div id="ctl00_PlaceHolderMain_ctl00_ctl01_phColumns_ctl00_column" class="dpl-col span-12-sm span-12-md" data-dpl-default-css-class="span-12-sm span-12-md" data-dpl-default-zone-id="BreadCrumbWebPartZone" data-dpl-column-id="B53B4BBB8EEB4457BA2A6C5430E1" data-dpl-default-tag-name="div"> <div class="ms-webpart-zone ms-fullWidth"> <div id="MSOZoneCell_WebPartctl00_ctl29_g_293d2499_1664_48f1_bbdb_58b7530b854f" class="s4-wpcell-plain ms-webpartzone-cell ms-webpart-cell-vertical-inline-table ms-webpart-cell-vertical ms-fullWidth "> <div class="ms-webpart-chrome ms-webpart-chrome-vertical ms-webpart-chrome-fullWidth "> <div WebPartID="293d2499-1664-48f1-bbdb-58b7530b854f" HasPers="false" id="WebPartctl00_ctl29_g_293d2499_1664_48f1_bbdb_58b7530b854f" width="100%" class="ms-WPBody noindex " allowDelete="false" style="" ><div id="ctl00_ctl29_g_293d2499_1664_48f1_bbdb_58b7530b854f" class="bread-crumb-padding wp-breadcrumb__mb0"> </div><div class="ms-clear"></div></div> </div> </div> </div> </div> </div> <div id="ctl00_PlaceHolderMain_ctl00_ctl02_row" class="dpl-row" data-dpl-row-id="D1BE7D2519F34B7DA96679133398" data-dpl-default-tag-name="div"> <div id="ctl00_PlaceHolderMain_ctl00_ctl02_phColumns_ctl00_column" class="dpl-col span-12-sm span-12-md" data-dpl-default-css-class="span-12-sm span-12-md" data-dpl-default-zone-id="RightTopWebPartZone" data-dpl-column-id="05CBD17AAF7B4B54934D9430744C" data-dpl-default-tag-name="div"> <menu class="ms-hide"> <ie:menuitem id="MSOMenu_Help" iconsrc="/_layouts/15/images/HelpIcon.gif" onmenuclick="MSOWebPartPage_SetNewWindowLocation(MenuWebPart.getAttribute('helpLink'), MenuWebPart.getAttribute('helpMode'))" text="Help" type="option" style="display:none"> </ie:menuitem> </menu> </div> </div> <div id="ctl00_PlaceHolderMain_ctl00_ctl03_row" class="dpl-row" data-dpl-row-id="E39CF5A32A80471B9095159D2FAA" data-dpl-default-tag-name="div"> <div id="ctl00_PlaceHolderMain_ctl00_ctl03_phColumns_ctl00_column" class="dpl-col span-12-sm span-12-md" data-dpl-default-css-class="span-12-sm span-12-md" data-dpl-default-zone-id="CenterWebPartZone" data-dpl-column-id="DB240D870CF84AB694293A93920B" data-dpl-default-tag-name="div"> <div class="ms-webpart-zone ms-fullWidth"> <div id="MSOZoneCell_WebPartctl00_ctl29_g_a12ca4de_2b6f_4907_8a95_136fe47ac9c5" class="s4-wpcell-plain ms-webpartzone-cell ms-webpart-cell-vertical-inline-table ms-webpart-cell-vertical ms-fullWidth "> <div class="ms-webpart-chrome ms-webpart-chrome-vertical ms-webpart-chrome-fullWidth "> <div WebPartID="a12ca4de-2b6f-4907-8a95-136fe47ac9c5" HasPers="false" id="WebPartctl00_ctl29_g_a12ca4de_2b6f_4907_8a95_136fe47ac9c5" width="100%" class="ms-WPBody noindex " allowDelete="false" style="" ><div id="ctl00_ctl29_g_a12ca4de_2b6f_4907_8a95_136fe47ac9c5"> <!--User Registration Starts --> <div class="ejp-user-registration"> <div class="ejp-user-registration__col ejp-user-registration__col--form"> <div class="ejp-user-registration__form-container"> <div id="ctl00_ctl29_g_a12ca4de_2b6f_4907_8a95_136fe47ac9c5_ctl00_RegistrationFormWrapper" class="js-user-register-form" data-config="{"serviceUrl":"https://services.journals.lww.com/IntegrationServices/AccountService.svc/","privacyUrl":"https://journals.lww.com/alzheimerjournal/_layouts/oaks.journals/privacy.aspx","eulaUrl":"/Documents/EULA.pdf","loginUrl":"https://journals.lww.com/alzheimerjournal/pages/login.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx","journalShortName":"alzheimerjournal","redirectUrl":"/alzheimerjournal/pages/register.aspx?ContextUrl=https%3a%2f%2fjournals.lww.com%2falzheimerjournal%2fsecure%2fpages%2fThanksForRegistering.aspx%3fReturnUrl%3d%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx","tokenKey":"AppSsoToken"}"></div> </div> </div> <div class="ejp-user-registration__col"> <div class="ejp-user-registration__user-icons"> <h2 class="sans-serif b user-icons__title ">When you鈥檙e registered, you can:</h2> <div class="cf w-100 pv3 sans-serif"> <div class="fl w-50 items-center user-icons__item pr3"> <div class="w-100 dt"> <div class="icon icon-1 dtc"></div> <div class="user-icons__text dtc v-top">Save and organize <div class="b">articles and videos</div></div> </div> </div> <div class="fl w-50 items-center user-icons__item pl3"> <div class="dt w-100"> <div class="icon icon-3 dtc"></div> <div class="user-icons__text dtc v-top">View your <div class="b">search history</div></div> </div> </div> </div> <div class="cf w-100 pv3 sans-serif "> <div class="fl w-50 items-center user-icons__item pr3"> <div class="w-100 dt"> <div class="icon icon-2 dtc"></div> <div class="user-icons__text dtc v-top">Save your <div class="b">frequent searches</div></div> </div> </div> <div class="fl w-50 items-center user-icons__item pl3"> <div class="w-100 dt"> <div class="icon icon-4 dtc"></div> <div class="user-icons__text dtc v-top">Manage your <div class="b">email alerts</div></div> </div> </div> </div> </div> </div> </div> </div><div class="ms-clear"></div></div> </div> </div> </div> </div> </div> </DIV> <div style='display:none' id='hidZone'></div> </div> <div id="DeltaFormDigest"> <script type="text/javascript">//<![CDATA[ var formDigestElement = document.getElementsByName('__REQUESTDIGEST')[0]; if (!((formDigestElement == null) || (formDigestElement.tagName.toLowerCase() != 'input') || (formDigestElement.type.toLowerCase() != 'hidden') || (formDigestElement.value == null) || (formDigestElement.value.length <= 0))) { formDigestElement.value = '0x3812B9B97ECDDBFD0E78639B516E10E1A50704928064F5AD2D07F3CB0404B270268059DA4BA1FA1020387ECD9B1D305CB1674B918A412BF9B446739A50F0CF61,24 Nov 2024 06:11:04 -0000';_spPageContextInfo.updateFormDigestPageLoaded = new Date(); } //]]> </script> </div> </div> <!-- Footer Delegate Control --> <footer class="ejp-footer"> <div class="container wk-grid-page-container"> <a class="ejp-footer__back-to-top-link"><i class="fa fa-angle-up b ejp-footer__back-to-top-link-icon"></i>Back to Top</a> <div class="ejp-footer__main-content"> <!-- Footer smart control --> <div class="ejp-footer__smart-control-section"> <section class="ejp-footer__smart-control-section-wrapper js-section-alert"> <div class="ejp-footer__smart-control-section-image-container"> <img src="https://images.journals.lww.com/alzheimerjournal/XLargeThumb.00002093-202407000-00000.CV.jpeg" id="ctl00_ctl56_FooterSmartControl_ctl00_imgAlertControl" alt="Current Issue Cover Image" class="" /> </div> <div class="ejp-footer__smart-control-section-text-holder"> <h4 id="ctl00_ctl56_FooterSmartControl_ctl00_headerAlertControl">Never Miss an Issue</h4> <div class="js-section-alert__content"> <span id="ctl00_ctl56_FooterSmartControl_ctl00_spanBodyAlertControl" class="ejp-footer__smart-control-section-info">Get new journal Tables of Contents sent right to your email inbox</span> <input name="ctl00$ctl56$FooterSmartControl$ctl00$userEmailAlertControl" type="text" id="ctl00_ctl56_FooterSmartControl_ctl00_userEmailAlertControl" class="js-section-alert__email" placeholder="Type your email" /> <span class="js-section-alert--error"></span> <button id="ctl00_ctl56_FooterSmartControl_ctl00_buttonAlertControl" type="button" class="js-section-alert__subscribe-button" data-alert-type="Etoc" data-subscribed-msg="You are now subscribed to receive eTOC alerts whenever new issues are published">Get New Issue Alerts</button> </div> </div> </section> <script type="text/javascript"> (function($) { $("#smartWpMostPopularLink").on('click', function() { window.location = "https://journals.lww.com/alzheimerjournal/pages/viewallmostpopulararticles.aspx?WT.mc_id=HPxADx20100319xMP"; }); })(jQuery); </script> </div> <div class="ejp-footer__info-holder"> <div id="ctl00_ctl56_divLeftColumn" class="ejp-footer__info-left-wrapper"> <div class="ejp-footer__info-block"> <h4 class="ejp-footer__info-block-header">Browse Journal Content</h4> <ul class="ejp-footer__info-block-two-col-list"> <li> <a href='/alzheimerjournal/pages/viewallmostpopulararticles.aspx' target='' rel="noopener">Most Popular</a> </li> <li> <a href='/alzheimerjournal/_layouts/1033/oaks.journals/informationforauthors.aspx' target='' rel="noopener">For Authors</a> </li> <li> <a href='/alzheimerjournal/pages/aboutthejournal.aspx' target='' rel="noopener">About the Journal</a> </li> <li> <a href='/alzheimerjournal/pages/issuelist.aspx' target='' rel="noopener">Past Issues</a> </li> <li> <a href='/alzheimerjournal/pages/currenttoc.aspx' target='' rel="noopener">Current Issue</a> </li> <li id="ctl00_ctl56_liRegister"><a id="ctl00_ctl56_lnkRegister" href="https://journals.lww.com/alzheimerjournal/pages/register.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx">Register on the website</a></li> <li id="ctl00_ctl56_liSubscribe" role="presentation"><a id="ctl00_ctl56_lnkSubscribe" href="https://shop.lww.com/p/0893-0341" target="_blank">Subscribe</a></li> <li id="ctl00_ctl56_liHyperSubscribeToEtoc"><a rel="nofollow" title href="javascript:javascript: alerts_ShowSubscribeeTOCPopup('Alzheimer Disease & Associated Disorders','alzheimerjournal','eTOC', 'eTOC');;" onclick="javascript: alerts_ShowSubscribeeTOCPopup('Alzheimer Disease & Associated Disorders','alzheimerjournal','eTOC', 'eTOC');"><span id="ctl00_ctl56_alertLinkControl_defaultText" class="hideOnFixed">Get eTOC Alerts</span></a> </li> </ul> </div> </div> <div id="ctl00_ctl56_divRightColumn" class="ejp-footer__info-right-wrapper"> <div id="ctl00_ctl56_divForJournalAuthors" class="ejp-footer__info-block"> <h4 class="ejp-footer__info-block-header">For Journal Authors</h4> <ul> <li class=''> <a href='/alzheimerjournal/_layouts/15/1033/oaks.journals/informationforauthors.aspx' target='' rel="noopener">Submit an article</a> </li> <li class=''> <a href='https://wkauthorservices.editage.com/' target='_blank' rel="noopener">How to publish with us</a> </li> </ul> </div> <div class="ejp-footer__info-block ejp-footer__info-block--custom-service"> <h4 class="ejp-footer__info-block-header">Customer Service</h4> <div id="liveagent_button_online_5730V0000019KUh" style="display: none; border: 0px none; cursor: pointer" onclick="liveagent.startChat('5730V0000019KUh')" class="live-chat__button live-chat__button--on"> <i class="live-chat__button-icon wk-icon-filled-dialogue-white-r"></i> <span class="live-chat__button-text">Live Chat</span> </div> <div id="liveagent_button_offline_5730V0000019KUh" style="display: none; border: 0px none;" class="live-chat__button live-chat__button--off"> <i class="live-chat__button-icon wk-icon-filled-dialogue-gray-r"></i> <span class="live-chat__button-text">Chat Offline</span> </div> <script type="text/javascript"> if (!window._laq) { window._laq = []; } window._laq.push(function () { liveagent.showWhenOnline('5730V0000019KUh', document.getElementById('liveagent_button_online_5730V0000019KUh')); liveagent.showWhenOffline('5730V0000019KUh', document.getElementById('liveagent_button_offline_5730V0000019KUh')); }); </script> <script type='text/javascript' src='https://c.la1-c1-ia5.salesforceliveagent.com/content/g/js/47.0/deployment.js'></script> <script type='text/javascript'> liveagent.init('https://d.la1-c1-ia5.salesforceliveagent.com/chat', '5720V00000158LL', '00Dd0000000dixc'); </script> <ul> <li class='ejp-footer--show-on-mobile'> <a href='https://lww.com/secure/pages/activatesubscription.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx' target='' rel="noopener">Activate your journal subscription</a> </li> <li class='ejp-footer--hide-on-mobile'> <a href='https://lww.com/secure/pages/activatesubscription.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx' target='' rel="noopener">Activate Journal Subscription</a> </li> <li class='ejp-footer--hide-on-mobile'> <a href='https://wkhlrp.my.site.com/LippincottOnlineHelpCenter/s/' target='' rel="noopener">Browse the help center</a> </li> <li class='ejp-footer--show-on-mobile'> <a href='https://wkhealth.force.com/lwwonline/s/topic/0TO0V000001YgLZWA0/lww-online?tabset-ddbfe=2' target='' rel="noopener">Help</a> </li> <li><span class="ejp-footer--show-on-mobile">Contact us at:</span> <ul> <li class="ejp-footer__contacts-wrapper ejp-footer__email-settings"> <div class="ejp-footer--show-on-mobile">Support:</div> <a href="https://www.tfaforms.com/4966570" id="ctl00_ctl56_custSupport" target="_blank">Submit a Service Request</a> </li> <li class="ejp-footer__contacts-wrapper ejp-footer__phone-settings"> <div class="ejp-footer--show-on-mobile ejp-footer__phone-settings--version"> <div id="ctl00_ctl56_telMobileUSA">TEL: (USA):</div> <div id="ctl00_ctl56_telMobileInt">TEL: (Int鈥檒):</div> </div> <div class="ejp-footer__phone-settings--holder"> <div> 800-638-3030 <span class="ejp-footer--hide-on-mobile">(within USA)</span> </div> <div> 301-223-2300 <span class="ejp-footer--hide-on-mobile">(international)</span> </div> </div> </li> </ul> </li> </ul> <ul><li> <button id="ot-sdk-btn" class="ot-sdk-show-settings ot-ejp-btn" onclick="return false;">Cookie Settings</button> </li> </ul> </div> </div> </div> <span id="ctl00_ctl56_FooterConfiguration" class="js-config-provider" data-config="{"loginConfiguration":{"serviceUrl":"https://services.journals.lww.com/IntegrationServices/AccountService.svc/Login","registerUrl":"https://journals.lww.com/alzheimerjournal/pages/register.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx","forgotPasswordUrl":"https://journals.lww.com/alzheimerjournal/pages/forgotpassword.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx","redirectUrl":"https://journals.lww.com/alzheimerjournal/pages/login.aspx?ContextUrl=%2falzheimerjournal%2fabstract%2f2020%2f01000%2ftype_2_diabetes_interacts_with_alzheimer_disease.2.aspx","tokenKey":"AppSsoToken","ssoLoginOptions":[],"customerService":{"customerServiceUSPhone":"(800) 638-3030","customerServiceInternationalPhone":"301-223-2300","customerServiceEmail":"customerservice@lww.com"},"useAlternativeAccountLinks":false},"commonConfiguration":{"commonEndpoints":{"addToFavoritesServiceUrl":"https://journals.lww.com/alzheimerjournal/_layouts/15/OAKS.Journals/UserCollectionsService.svc/AddToFavorites","saveSearchServiceUrl":"https://journals.lww.com/alzheimerjournal/_layouts/15/OAKS.Journals/UserCollectionsService.svc/SaveSearch","counterDataServiceUrl":"https://journals.lww.com/alzheimerjournal/_layouts/15/OAKS.Journals/DualAccessService.svc/SendCounterDataRequestByAN"},"kaltura":{"partnerId":"1315631","playerId":"52253872","kalturaWidgetUrl":"https://cdnapisec.kaltura.com/p/1315631/embedPlaykitJs/uiconf_id/52253872"},"brightCove":{"brightCoveScriptUrl":"https://players.brightcove.net/2324982687001/HyP0JSARx_default/index.min.js","dataAccount":"2324982687001","dataPlayer":"HyP0JSARx"},"math":{"libUrl":"https://cdn.jsdelivr.net/npm/mathjax@3/es5/tex-mml-chtml.js"},"recoWidget":{"journals":[{"Id":"alzheimerjournal","Version":"04.03","ProductCode":"aldad"}],"pubFilter":{},"clientId":"ejp_v3","libUrl":"https://assets.ovid.com/widget/v3/widget.js"},"sciteBadge":{"libUrl":"https://cdn.scite.ai/badge/scite-badge-latest.min.js"}}}"></span> </div> <div id="ctl00_ctl56_footerSocialDiv" class="ejp-footer__social-links ejp-footer--dashed-decore"> <ul id="ctl00_ctl56_socialList"> <li class=''> <a href='https://www.facebook.com/Alzheimer-Disease-Associated-Disorders-163742377014617/' target='_blank' title="Facebook" aria-label="Facebook" rel="noopener"> <img style='display:none' src=''> <i class='wk-icon-filled-facebook' aria-hidden="true"></i> </a> </li> <li class=''> <a href='https://X.com/adadlww' target='_blank' title="X" aria-label="X" rel="noopener"> <img style='display:none' src=''> <i class='wk-icon-filled-x' aria-hidden="true"></i> </a> </li> </ul> </div> <div class="ejp-footer__bottom-links"> <ul class="ejp-footer__useful-links"> <li><a id="ctl00_ctl56_hlkPrivacy" href="https://journals.lww.com/alzheimerjournal/_layouts/oaks.journals/privacy.aspx">Privacy Policy</a></li> <li><a id="ctl00_ctl56_hlkLegal" href="https://journals.lww.com/alzheimerjournal/_layouts/oaks.journals/disclaimer.aspx">Legal Disclaimer</a></li> <li><a id="ctl00_ctl56_hlkTermsOfUse" href="https://journals.lww.com/alzheimerjournal/_layouts/oaks.journals/terms.aspx">Terms of Use</a></li> <li><a id="ctl00_ctl56_hlkNIHPublicAccess" href="https://www.wolterskluwer.com/en/solutions/lippincott-journals/lippincott-open-access">Open Access Policy</a></li> <li class=''> <a href='/alzheimerjournal/Secure/Pages/feedback.aspx' target=''> <img style='display:none' src='' /> <i class=''></i> Feedback </a> </li> <li class=''> <a href='http://journals.lww.com/alzheimerjournal/_layouts/1033/oaks.journals/sitemap.aspx' target='blank'> <img style='display:none' src='' /> <i class=''></i> Sitemap </a> </li> <li class=''> <a href='/alzheimerjournal/_layouts/OAKS.Journals/feeds.aspx' target=''> <img style='display:none' src='' /> <i class=''></i> RSS Feeds </a> </li> <li class=''> <a href='https://lww.com/' target=''> <img style='display:none' src='' /> <i class=''></i> LWW Journals </a> </li> <li><a id="ctl00_ctl56_hlkCAPrivacyChoices" href="https://privacyportal-de.onetrust.com/webform/2217e117-526b-4696-8a98-8c402f8f2b81/5b049ba3-0106-4b77-a7da-5d12238c90a4">Your California Privacy Choices</a> <img src="/_layouts/1033/IMAGES/OAKS.Journals/CAPrivacyPolicy.png" id="ctl00_ctl56_imgCAPrivacyPolicyChoices" class="wk-footer__ca-privacy-logo" alt="California Consumer Privacy Act (CCPA) Opt-Out Icon" /> </li> </ul> <ul class="ejp-footer__copyright-block"> <li><span>Copyright © 2024</span></li> <li><a href="https://www.wolterskluwer.com/en/health" target="_blank">Wolters Kluwer Health, Inc. and/or its subsidiaries. All rights reserved.</a></li> </ul> </div> </div> </footer> </div> </div> <!--Scripts --> <!--<script src="~/js/ejp-scripts.js"></script> --> <script> $(document).on('click', '.yamm .dropdown-menu', function (e) { e.stopPropagation(); }); </script> <!-- Additional custom controls --> <!-- High Impact Advertisement --> <div id="ctl00_ctl59_adContainer" class="ej-advertisement ejp-advertisement-highimpact js-advertisement-highimpact"> <div class="ej-advertisement-content"> <div> <div id="ga_9687fc81-95b2-45ee-9f0b-18a64222fa23" class="ad-slot-container ad-slot-container-ga_9687fc81-95b2-45ee-9f0b-18a64222fa23" data-sizemap="[[[992, 500], [[300, 250]]], [[768, 180], [[728, 90]]], [[0, 0], [[300, 50]]]]" data-adpath="/15726702761/Desktop/alzheimerjournal/HighImpact" data-autoload="yes" data-outofpage="no" data-sticky="yes" data-slottargeting='' data-displayslug="yes" data-sticky-duration="10" data-name="HighImpact"></div> </div> </div> </div> <!-- Bottom Banner --> <!-- QuantcastTracker - don't have key in configuration DB, seems like controls is deprecated --> <!----> <div id="ga_Top1" class="ad-slot-container" data-sizemap="" data-adpath="/15726702761/Desktop/alzheimerjournal/Home/Interstitial" data-autoload="yes" data-outofpage="yes" data-sticky="no" data-slottargeting='' data-displayslug="yes" data-sticky-duration="0" data-name="Interstitial"></div> <script type="text/javascript"> //<![CDATA[ var Page_Validators = new Array(document.getElementById("ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError")); //]]> </script> <script type="text/javascript"> //<![CDATA[ var ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError = document.all ? document.all["ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError"] : document.getElementById("ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError"); ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError.display = "Dynamic"; ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError.validationGroup = "EmailValidationGroup"; ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError.evaluationfunction = "CustomValidatorEvaluateIsValid"; //]]> </script> <script type="text/javascript"> //<![CDATA[ var _spFormDigestRefreshInterval = 1440000;window.SPThemeUtils && SPThemeUtils.ApplyCurrentTheme(true); IsSPSocialSwitchEnabled = function() { return true; };var _fV4UI = true; function _RegisterWebPartPageCUI() { var initInfo = {editable: false,isEditMode: false,allowWebPartAdder: false,listId: "{d7dc827c-7ad0-4955-963b-ed8e6d88a88d}",itemId: 57,recycleBinEnabled: true,enableMinorVersioning: false,enableModeration: false,forceCheckout: false,rootFolderUrl: "\u002falzheimerjournal\u002fPages",itemPermissions:{High:0,Low:200769}}; SP.Ribbon.WebPartComponent.registerWithPageManager(initInfo); var wpcomp = SP.Ribbon.WebPartComponent.get_instance(); var hid; hid = document.getElementById("_wpSelected"); if (hid != null) { var wpid = hid.value; if (wpid.length > 0) { var zc = document.getElementById(wpid); if (zc != null) wpcomp.selectWebPart(zc, false); } } hid = document.getElementById("_wzSelected"); if (hid != null) { var wzid = hid.value; if (wzid.length > 0) { wpcomp.selectWebPartZone(null, wzid); } } }; function __RegisterWebPartPageCUI() { ExecuteOrDelayUntilScriptLoaded(_RegisterWebPartPageCUI, "sp.ribbon.js");} _spBodyOnLoadFunctionNames.push("__RegisterWebPartPageCUI");var __wpmExportWarning='This Web Part Page has been personalized. As a result, one or more Web Part properties may contain confidential information. Make sure the properties contain information that is safe for others to read. After exporting this Web Part, view properties in the Web Part description file (.WebPart) by using a text editor such as Microsoft Notepad.';var __wpmCloseProviderWarning='You are about to close this Web Part. It is currently providing data to other Web Parts, and these connections will be deleted if this Web Part is closed. To close this Web Part, click OK. To keep this Web Part, click Cancel.';var __wpmDeleteWarning='You are about to permanently delete this Web Part. Are you sure you want to do this? To delete this Web Part, click OK. To keep this Web Part, click Cancel.'; var Page_ValidationActive = false; if (typeof(ValidatorOnLoad) == "function") { ValidatorOnLoad(); } function ValidatorOnSubmit() { if (Page_ValidationActive) { return ValidatorCommonOnSubmit(); } else { return true; } } //]]> </script> <script type='text/javascript'>SP.SOD.set_prefetch(0);</script> <script type="text/javascript"> //<![CDATA[ var g_clientIdDeltaPlaceHolderMain = "DeltaPlaceHolderMain"; var g_clientIdDeltaPlaceHolderUtilityContent = "DeltaPlaceHolderUtilityContent"; Sys.Application.add_init(function() { $create(AjaxControlToolkit.ModalPopupBehavior, {"BackgroundCssClass":"Popup-Overlay","DropShadow":true,"PopupControlID":"ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_pnlunSubscribeToAlerts","dynamicServicePath":"/alzheimerjournal/pages/register.aspx","id":"unSubscribeToAlerts"}, null, null, $get("ctl00_ctl51_Header_UserActionTools_ucUnsubscribeToAlertsUserControl_dummyTargetControl")); }); Sys.Application.add_init(function() { $create(AjaxControlToolkit.ModalPopupBehavior, {"BackgroundCssClass":"Popup-Overlay","DropShadow":true,"PopupControlID":"ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_pnlSubscribeToEtoc","dynamicServicePath":"/alzheimerjournal/pages/register.aspx","id":"subscribeToEtoc"}, null, null, $get("ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_dummyTargetControl")); }); document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError').dispose = function() { Array.remove(Page_Validators, document.getElementById('ctl00_ctl51_Header_UserActionTools_SubscribeToEtocPopupControl_cvEmailError')); } g_QuickLaunchControlIds.push("zz1_TopNavigationMenu");_spBodyOnLoadFunctionNames.push('QuickLaunchInitDroppable'); var g_zz1_TopNavigationMenu = null; function init_zz1_TopNavigationMenu() { if (g_zz1_TopNavigationMenu == null) g_zz1_TopNavigationMenu = $create(SP.UI.AspMenu, null, null, null, $get('zz1_TopNavigationMenu')); } if(g_spPreFetchKeys) {{ g_spPreFetchKeys.push('SP.Core.js');}}EnsureScriptFunc('SP.Core.js', 'SP.UI.AspMenu', init_zz1_TopNavigationMenu); //]]> </script> </form> <span id="DeltaPlaceHolderUtilityContent"> </span> <script type="text/javascript">// <![CDATA[ var g_Workspace = "s4-workspace"; // ]]> </script> <div id="ctl00_ctl64_divAdConfig" data-adconfig="{"adTitle":"Advertisement","slotClass":"ad-slot-container","topBanner":{"sticky":"true","stickyDuration":"5000"},"lazyLoadingEnabled":false,"npiHash":"","pageTargeting":{}}" data-videoadconfig="{"serverURL":"https://pubads.g.doubleclick.net/gampad/ads","sizes":"320x180|640x360","overlayUnitPath":"/15726702761/Desktop/alzheimerjournal/Video/overlay","prerollUnitPath":"/15726702761/Desktop/alzheimerjournal/Video/pre-roll","postrollUnitPath":"/15726702761/Desktop/alzheimerjournal/Video/post-roll"}" class="js-ad-config"> </div> <div id="ctl00_ctl64_divScripts"><script type="text/plain" async="async" src="https://securepubads.g.doubleclick.net/tag/js/gpt.js" class="optanon-category-C0004"></script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/ads.js?v=05.24.00.023" defer="true"> </script> </div> <!-- Control to add scripts depending on settings from Configuration DB like --> <script type="text/javascript"> (function($) { if (false) { $(".top-microbar-container").addClass('top-microbar-container-moved').insertAfter(".advertisement-content_top"); } $(function () { if (false) { $( '<div class="top-banner-verify-email">Be sure to check your email to verify your new user account! Thanks!</div>') .insertAfter(".top-microbar-container"); } }); })(jQuery); </script> <script type="text/javascript"> window.twttr = (function(d, s, id) { var js, fjs = d.getElementsByTagName(s)[0], t = window.twttr || {}; if (d.getElementById(id)) return t; js = d.createElement(s); js.id = id; js.src = "https://platform.twitter.com/widgets.js"; fjs.parentNode.insertBefore(js, fjs); t._e = []; t.ready = function(f) { t._e.push(f); }; return t; }(document, "script", "twitter-wjs")); </script> <script type="text/javascript" src="https://lww.com/_layouts/15/oaks.journals/core/ee.js?v=05.24.00.023" defer="true"> </script> <script type="text/javascript"> function OTScriptExecutedEventHandler(e) { if (window.WKTracker && window.TrackingSetup) { window.TrackingSetup.api = window.TrackingSetup.api || {}; window.TrackingSetup.api.baseUrl = 'https://apim-hlrp-ejp-prod.azure-api.net/ee'; window.TrackingSetup.api.log = window.TrackingSetup.api.log || {}; window.TrackingSetup.api.resolve = window.TrackingSetup.api.resolve || {}; window.TrackingSetup.gdpr = window.TrackingSetup.gdpr || {}; window.TrackingSetup.gdpr.cookieUsageConsent = window.cookieUsageConsent || false; window.WKTracker.configure(window.TrackingSetup); window.WKTracker.track(); // Remove the event listener window.removeEventListener('OTScriptExecuted', OTScriptExecutedEventHandler); } } window.addEventListener('OTScriptExecuted', OTScriptExecutedEventHandler); </script> <script>(function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'8e773d513c594834',t:'MTczMjQyODY2NS4wMDAwMDA='};var a=document.createElement('script');a.nonce='';a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();</script></body> </html>