Lactoferrin supplements could aid in the reco

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href="https://maxcdn.bootstrapcdn.com/font-awesome/4.7.0/css/font-awesome.min.css" rel="stylesheet"> <link rel="stylesheet" href="https://ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.css">     <script src="https://cdn.jsdelivr.net/npm/@mediakind/mkplayer@1.11.0/mkplayer.min.js"></script> <link href="https://cdn.jsdelivr.net/npm/@mediakind/mkplayer@1.11.0/mkplayer-ui.min.css" rel="stylesheet">   <script type="text/javascript" src="//s7.addthis.com/js/300/addthis_widget.js#pubid=ra-609e0dbb00597456"></script> <script type="text/javascript"> var addthis_share = addthis_share || {} addthis_share = { passthrough : { twitter: { text: 'Lactoferrin supplements could aid in the recovery of COVID19 & other Respiratory Tract Infections', via: 'EurekAlert @HudUniPR', } } } </script> <meta name="twitter:card" content="summary_large_image"> <meta name="twitter:site" content="@EurekAlert"> <meta name="twitter:domain" content="www.eurekalert.org"> <meta name="twitter:title" content="Lactoferrin supplements could aid in the recovery of COVID19 & other Respiratory Tract Infections"> <meta name="twitter:description" content="The findings of a study, headed by the University of Huddersfield鈥檚 Dr Hamid Merchant from the Department of Pharmacy, is one of the first meta-analyses carried out on multiple independent lactoferrin research studies. The study has made evident that the administration of lactoferrin, of which has proven to be a key ingredient for our natural defence systems against invading viruses, shows promising efficacy in reducing the risk of RTIs and also has the potential to be used adjunct to COVID19."> <meta name="twitter:creator" content="HudUniPR"> <meta property="og:image" content="https://earimediaprodweb.azurewebsites.net/Api/v1/Multimedia/1f3f0361-0a9e-4775-9ce4-32a75d5a65af/Rendition/thumbnail/Content/Public"> <meta name="twitter:image" content="https://earimediaprodweb.azurewebsites.net/Api/v1/Multimedia/1f3f0361-0a9e-4775-9ce4-32a75d5a65af/Rendition/thumbnail/Content/Public"> <meta property="og:title" content="Lactoferrin supplements could aid in the recovery of COVID19 & other Respiratory Tract Infections"> <meta property="og:description" content="The findings of a study, headed by the University of Huddersfield鈥檚 Dr Hamid Merchant from the Department of Pharmacy, is one of the first meta-analyses carried out on multiple independent lactoferrin research studies. 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The study has made evident that the administration of lactoferrin, of which has proven to be a key ingredient for our natural defence systems against invading viruses, shows promising efficacy in reducing the risk of RTIs and also has the potential to be used adjunct to COVID19.</strong> <a href="/multimedia/956773">view <span class="no-break-text">more <i class="fa fa-angle-right"></i></span></a></p> <p class="credit">Credit: Pexels</p> </figcaption> </figure> <p>THE antiviral properties of lactoferrin makes it a great natural supplement that could also be used as an adjunct for COVID-19 and for various other Respiratory Tract Infections (RTIs) according to a team of researchers led by the University of Huddersfield. </p> <p>Lactoferrin is a protein naturally found in breastmilk, for example in cow milk and human milk, and is also found in fluids in the eye, nose, respiratory tract, intestine, and elsewhere.  The benefits are well documented however, it wasn’t known if taking the molecule as a supplement would have the same beneficial value, until now. </p> <p>The <a href="https://www.sciencedirect.com/science/article/pii/S2405457721003077?dgcid">findings of the study</a>, headed by the University’s <a href="https://pure.hud.ac.uk/en/persons/hamid-merchant">Dr Hamid Merchant</a> from the University’s <a href="https://www.hud.ac.uk/pharmacy/">Department of Pharmacy</a> is one of the first meta-analyses carried out on multiple independent lactoferrin clinical trials that is now published in an official publication of the <a href="https://www.espen.org/" target="_blank">European Society for Clinical Nutrition and Metabolism (ESPEN)</a>. The study has made evident that the administration of Lactoferrin shows promising efficacy in reducing the risk of RTIs, which is proven to be a key ingredient for our natural defence systems against invading viruses. </p> <blockquote> <p><em>“This is a very promising molecule which can be adopted as an adjunct therapy for COVID-19 and could be part of a daily routine for people to take, along with vitamin C, D and Zinc supplements to keep our immune system healthy. Particularly now winter is almost upon us we need this extra protection a lot more now than during the summer.”</em></p> <p>Dr Hamid Merchant, University of Huddersfield</p> </blockquote> <p><strong>Lactoferrin - a great supplement</strong></p> <p>It is this antiviral property of lactoferrin that makes it a great supplement for use as an adjunct for COVID-19 and other respiratory infections, but Dr Merchant believes these are still preliminary findings and warrants further evidence from a large, well-designed randomised controlled trial. </p> <p>“Given the high clinical importance of respiratory tract infections amid the COVID-19 pandemic, we aimed to systematically examine the interventional Randomised Clinical Trials on the ef铿乧acy of bovine lactoferrin in preventing the occurrence of RTIs,” said <a href="https://pure.hud.ac.uk/en/persons/syed-shahzad-hasan">Dr Syed Hasan,</a> another of the University’s researchers involved in the study. </p> <p>“The administration of Lactoferrin showed promising ef铿乧acy in reducing the risk of RTIs and may also have a beneficial role in managing symptoms and recovery of patients suffering from RTIs,” he said. </p> <p>“Current evidence also favours lactoferrin forti铿乧ation of infant formula - it won't be long until parents should be able to find lactoferrin fortified infant formulas readily available on the shelves,” Dr Merchant added.</p> <p><strong>Supplements dissolved slowly in the mouth tend to be superior</strong></p> <p>Lactoferrin is prepared by specialised dairy companies who make milk, infant formulas or milk-based products who isolate this biomolecule from the milk and various other companies then procure it to sell as a supplement.</p> <p>However, Dr Merchant argues that lots of low cost lactoferrin supplements being sold online are not of desired quality because with it being a biomolecule that is classed as a nutritional supplement, the production of lactoferrin isn’t legally enforced to follow the same strict regulatory process as for medicines. </p> <p>The natural form of lactoferrin isolated from the milk by a specialised filtration process have superior biological properties than the most lactoferrin products that are chemically processed and treated. Moreover, supplements available in the form of orodispersible tablets (dissolved slowly in the mouth) are superior to commonly available lactoferrin products that are meant to be swallowed with water. The buccal tablets not only increase the mucosal concentration of Lactoferrin but also helps with its absorption and avoids its deterioration by the stomach acid. </p> <p>“This is a very promising molecule which can be adopted as an adjunct therapy for COVID-19 and could be part of a daily routine for people to take, along with vitamin C, D and Zinc supplements to keep our immune system healthy. Particularly now winter is almost upon us we need this extra protection a lot more now than during the summer,” concluded Dr Merchant. </p> <p>Members of the team who also helped with the study included international researchers Akbar Shoukat Ali from The Aga Khan University Karachi and Chia Siang Kow from The Monash University Malaysia.</p> <p style="text-align: center;">###</p> <hr class="hidden-xs hidden-sm" /> <hr class="major visible-sm" /> <div class="featured_image"> <div class="details"> <div class="well"> <h4>Journal</h4> <p>Clinical Nutrition ESPEN</p> </div> <div class="well"> <h4>DOI</h4> <p><a href="http://dx.doi.org/10.1016/j.clnesp.2021.08.019" target="_blank">10.1016/j.clnesp.2021.08.019 <i class="fa fa-sign-out"></i></a></p> </div> <div class="well"> <h4>Method of Research</h4> <p>Meta-analysis</p> </div> <div class="well"> <h4>Subject of Research</h4> <p>Cells</p> </div> <div class="well"> <h4>Article Title</h4> <p>Lactoferrin reduces the risk of respiratory tract infections: A meta-analysis of randomized controlled trials</p> </div> <div class="well"> <h4>Article Publication Date</h4> <p>3-Sep-2021</p> </div> <div class="well"> <h4>COI Statement</h4> <p>HAM is on a scientific advisory board for a lactoferrin supplement product but does not have any financial or other affiliation with the company and has neither received any funding or financial reimbursements. HAM is committed to promote the science behind Lf and its immunomodulatory role in the prevention and management of infections.</p> </div> </div> </div> </div> <div class="well article_disclaimer hidden-search"> <p><strong>Disclaimer:</strong> AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.</p> </div> <div class="toolbar hidden-print hidden-search"> <div class='col-xs-6'> <div class="addthis_inline_share_toolbox_pnaa"></div> </div> <div class='col-xs-6'> <div class="article-tools pull-right"> <div class="addthis_inline_share_toolbox_62ef"></div> </div> </div> </div> </article> </div> <aside id="sidebar-content" class="white col-md-4"> <section class="widget"> <div class="widget-content"> <div class="contact-info"> <p><strong>Media Contact</strong></p> <p> Nicola Werritt<br/> University of Huddersfield<br /> <a href="mailto:nicola.werritt@hud.ac.uk"> nicola.werritt@hud.ac.uk </a><br/> Office: 01-484-47-3315<br/> </p> </div> </div> </section> <section class="widget"> <div class="widget-content"> <div class="contact-info"> <p><strong>Expert Contact</strong></p> <p> Dr Hamid Merchant<br/> University of Huddersfield<br /> <a href="mailto:hamid.merchant@hud.ac.uk"> hamid.merchant@hud.ac.uk </a><br/> <a href="http://www.twitter.com/@huddersfielduni" target="_blank"> <i class="fa fa-twitter"></i> @huddersfielduni </a><br/> </p> </div> </div> </section> <hr class="hidden-xs hidden-sm"> <hr class="major visible-xs visible-sm"> <section class="widget hidden-print"> <h3 class="widget-title red">More on this News Release</h3> <div class="widget-content"> <aside class="more"> <a href="/news-releases/932115"> <h3>Lactoferrin supplements could aid in the recovery of COVID19 & other Respiratory Tract Infections</h3> </a> <p class="meta_institute">University of Huddersfield</p> <dl class="dl-horizontal meta stacked"> <dt class="yellow">Journal</dt> <dd class="yellow"><em>Clinical Nutrition ESPEN</em></dd> <dt class="red">DOI</dt> <dd class="red"><em>10.1016/j.clnesp.2021.08.019</em></dd> </dl> </aside> <div class="row"> <div class="col-sm-6 col-md-12"> <h4 class="widget-subtitle">Keywords</h4> <nav class="tag-cloud"> <ul class="tags"> <li class="active ea-keyword"> <a href="#"> <span class="ea-keyword__path">/Applied sciences and engineering/Food science/Beverages/</span><span class="ea-keyword__short">Milk</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path">/Health and medicine/Diseases and disorders/Infectious diseases/Microbial infections/Viral infections/</span><span class="ea-keyword__short">COVID 19</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Health and medicine/Clinical medicine/Clinical studies/</span><span class="ea-keyword__short">Drug studies</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Applied sciences and engineering/Risk management/</span><span class="ea-keyword__short">Risk reduction</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Applied sciences and engineering/Applied mathematics/Statistics/Statistical analysis/</span><span class="ea-keyword__short">Metaanalysis</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Health and medicine/Clinical medicine/Medical treatments/Drug therapy/Medications/</span><span class="ea-keyword__short">Antivirals</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Scientific community/Research programs/</span><span class="ea-keyword__short">Clinical research</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Life sciences/Biochemistry/Biomolecules/Nutrients/Vitamins/</span><span class="ea-keyword__short">Vitamin C</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Life sciences/Organismal biology/Anatomy/</span><span class="ea-keyword__short">Immune system</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Health and medicine/Human health/Human biology/Human physiology/</span><span class="ea-keyword__short">Breast feeding</span> </a> </li> <li class="ea-keyword"> <a href="#"> <span class="ea-keyword__path"> /Health and medicine/Pharmaceuticals/</span><span class="ea-keyword__short">Drug therapy</span> </a> </li> </ul> </nav> </div> </div> </div> <h4 class="widget-subtitle">Additional Multimedia</h4> <div class="multimedia-grid"> <div class="multimedia-grid__grid-item"> <a href="/multimedia/956772"> <div class="multimedia-grid__image"> <img src="https://earimediaprodweb.azurewebsites.net/Api/v1/Multimedia/af799e90-bccb-4b23-96b5-075b0ed91ba0/Rendition/thumbnail/Content/Public" alt="Lactoferrin supplements could aid recovery of COVID19 & Respiratory Infections"> </div> <div class="multimedia-grid__title"> Lactoferrin supplements could aid recovery of COVID19 & Respiratory Infections </div> </a> </div> </div> <div class="col-sm-6 col-md-12"> <h4 class="widget-subtitle">Original Source</h4> <a href="https://www.hud.ac.uk/news/2021/october/hamid-merchant-lactoferrin-supplement-research/" style="overflow-wrap:break-word" target="_blank"> https://www.hud.ac.uk/news/2021/october/hamid-merchant-lactoferrin-supplement-research/ <i class="fa fa-sign-out"></i></a> </div> </section> </aside> </div> </div> </div> <footer id="footer" class="hidden-print hidden-search"> <div class="container"> <div class="row"> <div class="col-sm-5 col-sm-push-7"> <p class="logo"> <img src="/images/logo-footer.png" alt="EurekAlert! 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