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InVisionFirst®-Lung | NeoGenomics Laboratories

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Island</option><option value="Clipperton Island">Clipperton Island</option><option value="Cocos (Keeling) Islands">Cocos (Keeling) Islands</option><option value="Colombia">Colombia</option><option value="Comoros">Comoros</option><option value="Congo - Brazzaville">Congo - Brazzaville</option><option value="Congo - Kinshasa">Congo - Kinshasa</option><option value="Cook Islands">Cook Islands</option><option value="Costa Rica">Costa Rica</option><option value="Croatia">Croatia</option><option value="Cuba">Cuba</option><option value="Curaçao">Curaçao</option><option value="Cyprus">Cyprus</option><option value="Czechia">Czechia</option><option value="Côte d’Ivoire">Côte d’Ivoire</option><option value="Denmark">Denmark</option><option value="Diego Garcia">Diego Garcia</option><option value="Djibouti">Djibouti</option><option value="Dominica">Dominica</option><option value="Dominican Republic">Dominican Republic</option><option value="Ecuador">Ecuador</option><option value="Egypt">Egypt</option><option value="El Salvador">El Salvador</option><option value="Equatorial Guinea">Equatorial Guinea</option><option value="Eritrea">Eritrea</option><option value="Estonia">Estonia</option><option value="Eswatini">Eswatini</option><option value="Ethiopia">Ethiopia</option><option value="Falkland Islands">Falkland Islands</option><option value="Faroe Islands">Faroe Islands</option><option value="Fiji">Fiji</option><option value="Finland">Finland</option><option value="France">France</option><option value="French Guiana">French Guiana</option><option value="French Polynesia">French Polynesia</option><option value="French Southern Territories">French Southern Territories</option><option value="Gabon">Gabon</option><option value="Gambia">Gambia</option><option value="Georgia">Georgia</option><option value="Germany">Germany</option><option value="Ghana">Ghana</option><option value="Gibraltar">Gibraltar</option><option value="Greece">Greece</option><option value="Greenland">Greenland</option><option value="Grenada">Grenada</option><option value="Guadeloupe">Guadeloupe</option><option value="Guam">Guam</option><option value="Guatemala">Guatemala</option><option value="Guernsey">Guernsey</option><option value="Guinea">Guinea</option><option value="Guinea-Bissau">Guinea-Bissau</option><option value="Guyana">Guyana</option><option value="Haiti">Haiti</option><option value="Heard &amp; McDonald Islands">Heard & McDonald Islands</option><option value="Honduras">Honduras</option><option value="Hong Kong SAR China">Hong Kong SAR China</option><option value="Hungary">Hungary</option><option value="Iceland">Iceland</option><option value="India">India</option><option value="Indonesia">Indonesia</option><option value="Iran">Iran</option><option value="Iraq">Iraq</option><option value="Ireland">Ireland</option><option value="Isle of Man">Isle of Man</option><option value="Israel">Israel</option><option value="Italy">Italy</option><option value="Jamaica">Jamaica</option><option value="Japan">Japan</option><option value="Jersey">Jersey</option><option value="Jordan">Jordan</option><option value="Kazakhstan">Kazakhstan</option><option value="Kenya">Kenya</option><option value="Kiribati">Kiribati</option><option value="Kosovo">Kosovo</option><option value="Kuwait">Kuwait</option><option value="Kyrgyzstan">Kyrgyzstan</option><option value="Laos">Laos</option><option value="Latvia">Latvia</option><option value="Lebanon">Lebanon</option><option value="Lesotho">Lesotho</option><option value="Liberia">Liberia</option><option value="Libya">Libya</option><option value="Liechtenstein">Liechtenstein</option><option value="Lithuania">Lithuania</option><option value="Luxembourg">Luxembourg</option><option value="Macao SAR China">Macao SAR China</option><option value="Madagascar">Madagascar</option><option value="Malawi">Malawi</option><option value="Malaysia">Malaysia</option><option value="Maldives">Maldives</option><option value="Mali">Mali</option><option value="Malta">Malta</option><option value="Marshall Islands">Marshall Islands</option><option value="Martinique">Martinique</option><option value="Mauritania">Mauritania</option><option value="Mauritius">Mauritius</option><option value="Mayotte">Mayotte</option><option value="Mexico">Mexico</option><option value="Micronesia">Micronesia</option><option value="Moldova">Moldova</option><option value="Monaco">Monaco</option><option value="Mongolia">Mongolia</option><option value="Montenegro">Montenegro</option><option value="Montserrat">Montserrat</option><option value="Morocco">Morocco</option><option value="Mozambique">Mozambique</option><option value="Myanmar (Burma)">Myanmar (Burma)</option><option value="Namibia">Namibia</option><option value="Nauru">Nauru</option><option value="Nepal">Nepal</option><option value="Netherlands">Netherlands</option><option value="Netherlands Antilles">Netherlands Antilles</option><option value="New Caledonia">New Caledonia</option><option value="New Zealand">New Zealand</option><option value="Nicaragua">Nicaragua</option><option value="Niger">Niger</option><option value="Nigeria">Nigeria</option><option value="Niue">Niue</option><option value="Norfolk Island">Norfolk Island</option><option value="Northern Mariana Islands">Northern Mariana Islands</option><option value="North Korea">North Korea</option><option value="North Macedonia">North Macedonia</option><option value="Norway">Norway</option><option value="Oman">Oman</option><option value="Outlying Oceania">Outlying Oceania</option><option value="Pakistan">Pakistan</option><option value="Palau">Palau</option><option value="Palestinian Territories">Palestinian Territories</option><option value="Panama">Panama</option><option value="Papua New Guinea">Papua New Guinea</option><option value="Paraguay">Paraguay</option><option value="Peru">Peru</option><option value="Philippines">Philippines</option><option value="Pitcairn Islands">Pitcairn Islands</option><option value="Poland">Poland</option><option value="Portugal">Portugal</option><option value="Puerto Rico">Puerto Rico</option><option value="Qatar">Qatar</option><option value="Romania">Romania</option><option value="Russia">Russia</option><option value="Rwanda">Rwanda</option><option value="Réunion">Réunion</option><option value="Samoa">Samoa</option><option value="San Marino">San Marino</option><option value="Sark">Sark</option><option value="Saudi Arabia">Saudi Arabia</option><option value="Senegal">Senegal</option><option value="Serbia">Serbia</option><option value="Seychelles">Seychelles</option><option value="Sierra Leone">Sierra Leone</option><option value="Singapore">Singapore</option><option value="Sint Maarten">Sint Maarten</option><option value="Slovakia">Slovakia</option><option value="Slovenia">Slovenia</option><option value="Solomon Islands">Solomon Islands</option><option value="Somalia">Somalia</option><option value="South Africa">South Africa</option><option value="South Georgia &amp; South Sandwich Islands">South Georgia & South Sandwich Islands</option><option value="South Korea">South Korea</option><option value="South Sudan">South Sudan</option><option value="Spain">Spain</option><option value="Sri Lanka">Sri Lanka</option><option value="St. Barthélemy">St. Barthélemy</option><option value="St. Helena">St. Helena</option><option value="St. Kitts &amp; Nevis">St. Kitts & Nevis</option><option value="St. Lucia">St. Lucia</option><option value="St. Martin">St. Martin</option><option value="St. Pierre &amp; Miquelon">St. Pierre & Miquelon</option><option value="St. Vincent &amp; Grenadines">St. Vincent & Grenadines</option><option value="Sudan">Sudan</option><option value="Suriname">Suriname</option><option value="Svalbard &amp; Jan Mayen">Svalbard & Jan Mayen</option><option value="Sweden">Sweden</option><option value="Switzerland">Switzerland</option><option value="Syria">Syria</option><option value="São Tomé &amp; Príncipe">São Tomé & Príncipe</option><option value="Taiwan">Taiwan</option><option value="Tajikistan">Tajikistan</option><option value="Tanzania">Tanzania</option><option value="Thailand">Thailand</option><option value="Timor-Leste">Timor-Leste</option><option value="Togo">Togo</option><option value="Tokelau">Tokelau</option><option value="Tonga">Tonga</option><option value="Trinidad &amp; Tobago">Trinidad & Tobago</option><option value="Tristan da Cunha">Tristan da Cunha</option><option value="Tunisia">Tunisia</option><option value="Turkmenistan">Turkmenistan</option><option value="Turks &amp; Caicos Islands">Turks & Caicos Islands</option><option value="Tuvalu">Tuvalu</option><option value="Türkiye">Türkiye</option><option value="U.S. Outlying Islands">U.S. Outlying Islands</option><option value="U.S. Virgin Islands">U.S. Virgin Islands</option><option value="Uganda">Uganda</option><option value="Ukraine">Ukraine</option><option value="United Arab Emirates">United Arab Emirates</option><option value="United Kingdom">United Kingdom</option><option value="United States">United States</option><option value="Uruguay">Uruguay</option><option value="Uzbekistan">Uzbekistan</option><option value="Vanuatu">Vanuatu</option><option value="Vatican City">Vatican City</option><option value="Venezuela">Venezuela</option><option value="Vietnam">Vietnam</option><option value="Wallis &amp; Futuna">Wallis & Futuna</option><option value="Western Sahara">Western Sahara</option><option value="Yemen">Yemen</option><option value="Zambia">Zambia</option><option value="Zimbabwe">Zimbabwe</option><option value="Åland Islands">Åland Islands</option></select> </div> </div></div></div> <div class="js-form-item form-item js-form-type-select form-type-select js-form-item-interest form-item-interest"> <label for="edit-interest" class="js-form-required form-required">I am interested in</label> <select data-drupal-selector="edit-interest" id="edit-interest" name="interest" class="form-select required" required="required" aria-required="true"><option value="" selected="selected">- Select -</option><option value="Clinical">Clinical</option><option value="Pharma">Pharma</option><option value="Informatics">Informatics</option><option value="Research Project">Research Project</option><option value="Patient">I am a patient</option><option value="Other">Other</option></select> </div> <div class="js-form-item form-item js-form-type-textarea form-type-textarea js-form-item-comments form-item-comments"> <label for="edit-comments" class="js-form-required form-required">Comments</label> <div class="form-textarea-wrapper"> <textarea data-drupal-selector="edit-comments" id="edit-comments" name="comments" rows="5" cols="60" class="form-textarea required resize-vertical" required="required" aria-required="true"></textarea> </div> </div> <div class="hidden js-form-item form-item js-form-type-select form-type-select js-form-item-sign-me-up-for form-item-sign-me-up-for"> 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id="layout-hero"> <div class="hero-wrap"> <div class="hero-content"> <div class="region region-hero"> <div class="views-element-container block block-views block-views-blockdefault-header-block-1" id="block-views-block-default-header-block-1"> <div><div class="view view-default-header view-id-default_header view-display-id-block_1 js-view-dom-id-6b79c5f6368543bd9f130247e1a0a24904f29235be3a972708f09285f1ccb07f"> <div class="view-content"> <div class="views-row"><div class="views-field views-field-field-media-image-3"><div class="field-content"><div class="node-header large"> <div class="node-header-image" data-node-header-image="/sites/default/files/hero-image/InVisionFirst-Lung-header-banner-dark.jpg"> <div class="node-header-tab"></div> <div class="node-header-content"> <div class="node-header-wrap"> <h1 class="large">InVisionFirst®-Lung</h1> <h4 class="page-subtitle">Liquid Biopsy Assay</h4> </div> </div> </div> </div></div></div></div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="layout-above-content"> <div class="wrap-above-content"> <div class="above-content-content"> <div class="region region-above-content"> <div id="block-neogenomics-breadcrumbs" class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> InVisionFirst®-Lung</li> </ol> </nav> </div> </div> </div> </div> </div> <main role="main" class="layout-main"> <div class="wrap-main"> <div class="main-content"> <section class="no-sidebar content-wrap"> <div class="layout-content"> <a id="main-content" tabindex="-1"></a> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <div id="block-neogenomics-content" class="block block-system block-system-main-block"> <article data-history-node-id="1155" class="node node--type-promo node--view-mode-full"> <div class="node__content"> <div class="field field--name-field-section field--type-entity-reference-revisions field--label-hidden field__items"> <div class="paragraph paragraph--type--columns paragraph--view-mode--default corporate-pattern-bg"> <div id="" class="col-three-fourth-fourth padding-top-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p class="large">InVisionFirst<sup>®</sup>-Lung is an NGS-based liquid biopsy test that detects actionable genes relevant to the treatment and management of advanced non-small cell lung cancer (NSCLC)&nbsp;</p> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default corporate-pattern-bg"> <div id="" class="col-half padding-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>Liquid biopsy and tissue-based analysis are complementary approaches for molecular testing for biomarker assessment. A recent consensus statement from the International Association for the Study of Lung Cancer (IASLC, June 2021) discusses the innate limitations to tissue-based testing related to inadequate or insufficient tissue, challenging biopsy locations and turnaround time for rapid treatment decisions and state liquid biopsy is an acceptable initial approach for biomarker evaluation at time of diagnosis, as well as for monitoring the efficacy of targeted therapies<sup>1</sup>.</p> <p>InVisionFirst<sup>®</sup>-Lung delivers biomarker results in <strong>7 days*</strong> and may overcome many of these challenges seen with tissue-based testing in order to make fast and informed precision oncology decisions for advanced NSCLC patients.</p> <p><strong>Note</strong>:&nbsp; If you are a patient looking for information on InVisionFirst<sup>®</sup>-Lung, please visit our <a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="00719064-29c6-4c75-8862-1044cd99aafb" href="/node/1572">Patient Resource</a> section.</p> </div> </div> </div> </div> </div> </div> <div id="" class="paragraph paragraph--type--text-image-equal-height-columns paragraph--view-mode--default"> <div class="equal-height-image-section img-right"> <div class="equal-height-image-content"> <div id="paragraph-id-730" class="media-wrap lazyload-bg" style=";background-image: url('/sites/default/files/styles/lazy_load/public/2021-07/iStock-1202259529.jpg?itok=RIq8_Ffo');" data-lazyload="/sites/default/files/2021-07/iStock-1202259529.jpg"></div> <div class="content-wrap" style=""> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h3>Challenges we face with testing tumor tissue in advanced NSCLC</h3> <ul> <li>Approximately 80% of NSCLC patients do not have adequate tumor specimen for complete tissue genotyping for all eight guideline-recommended biomarkers.<sup>1</sup></li> <li>~1 in 2 patients with advanced or metastatic NSCLC may be eligible for a targeted therapy.<sup>2</sup></li> <li>Turn-around time for tissue specimen collection-to-analysis is usually longer than for liquid biopsy testing and may not be the optimal approach for all patients.<sup>1</sup></li> </ul> <p><strong>InVisionFirst<sup>®</sup>-Lung is F.A.S.T. approach to biomarker testing</strong><br> <strong>F</strong>ocused approach tailored for advanced NSCLC patients<br> <strong>A</strong>ctionable results to inform patient management<br> <strong>S</strong>ensitive &amp; Specific to accurately identify tumor mutations found at very low levels in blood<br> <strong>T</strong>imely results delivered within 7 days*</p> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--resources paragraph--view-mode--default"> <h4 class="resources-title">Resources</h4> <div class="field field--name-field-links field--type-link field--label-hidden field__items"> <div class="field__item"> <a href="/sites/default/files/2021-07/InVisionFirst-Lung-Tech-Sheet-062920-Final.pdf" tabindex="0" target="_blank"> InVisionFirst®- Lung Technical Sheet </a> </div> <div class="field__item"> <a href="/sites/default/files/2021-11/IVFL-gene-card_CORP-MRKT-0072_110221_Final.pdf" tabindex="0" target="_blank"> InVisionFirst®- Lung Gene Card </a> </div> <div class="field__item"> <a href="/sites/default/files/2023-07/InVisionFirst-Lung-Medical-Necessity-Tool-V2-CORP-MRKT-0082_071323_Final.pdf" tabindex="0" target="_blank"> InVisionFirst®- Lung Medical Necessity Tool </a> </div> <div class="field__item"> <a href="/sites/default/files/requisitions/Neo_InvisionFirstLung_LiquidBiopsy_Requisition_CORP-MRKT-0066_061724_Final_FF.pdf" tabindex="0" target="_blank"> Test Requisition Form </a> </div> </div> </div> <div id="" class="paragraph paragraph--type--content-highlight paragraph--view-mode--default"> <div class="highlight-section img-left"> <div id="highlight-id-1200" class="media-wrap lazyload-bg" style="background-image: url('/sites/default/files/styles/lazy_load/public/2021-11/Sasha_web_small.png?itok=CBEp2CNM');" data-lazyload="/sites/default/files/2021-11/Sasha_web_small.png"></div> <div class="highlight-content-wrap"> <div class="highlight-content"> <h5 class="highlight-pill">Sasha&#039;s Story</h5> <div class="highlight-body"><p>“My liquid biopsy test has potentially bought me several more years that I wouldn’t have had otherwise. That’s something that money can’t buy.” &nbsp;</p> <p class="disclaimer"><span style="color:#ffffff;">Sasha was a warrior and fought to make the world around her a better place, Sasha lost her battle with Lung Cancer in 2021. At NeoGenomics, we are extremely grateful to Sasha and her family for sharing the journey with us as we continue to focus on improving outcomes for patients daily.</span></p> </div> <div class="field--name-field-link"> <a href="/sites/default/files/2022-03/Inivata_Sashastory_CORP-MRKT-0080_033022_Final_Digital.pdf" class="small-upper"> Read Sasha&#039;s Story </a> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default"> <div id="" class="col-full padding-top-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h2 id="concordance" class="text-align-center"><strong>Accurate &amp; Actionable</strong></h2> <p class="text-align-center">Published in the largest prospective molecular diagnostics study in NSCLC published up to date in <a href="https://pubmed.ncbi.nlm.nih.gov/32914040/" target="_blank">JCO Precision Oncology</a>.</p> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default"> <div id="" class="col-third padding-top-bottom-50"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p style="text-align: center;"><strong><span style="font-size:60px;line-height:1em">97.8%</span></strong></p> <p style="text-align: center;"><span style="font-size:18px;">concordance with matched tumor tissue</span></p> </div> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p style="text-align: center;"><strong><span style="font-size:60px;line-height:1em">26%</span></strong></p> <p style="text-align: center;"><span style="font-size:18px;">more actionable alterations detected versus standard-of-care tissue testing</span></p> </div> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p style="text-align: center;"><strong><span style="font-size:60px;line-height:1em">7</span></strong></p> <p style="text-align: center;"><span style="font-size:18px;">day delivery upon sample receipt for fast and timely results*</span></p> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default corporate-pattern-bg"> <div id="" class="col-full padding-top-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h2 id="gene-panel"><strong>Focused panel that detects 37 genes relevant to treatment and management of NSCLC</strong></h2> <ul> <li>Includes all 10 guideline recommended genes with actionable targeted therapies</li> <li>Supports the therapeutic decisions in patients diagnosed with NSCLC</li> </ul> <p>&nbsp;</p> <ul class="newspaper-col-4 list-unstyled gene-list sm-2"> <li><span class="gene border-left-red">ALK</span></li> <li><span class="gene">BRAF</span></li> <li><span class="gene border-left-purple">EGFR</span></li> <li><span class="gene border-left-purple">ERBB2 (HER2)</span></li> <li><span class="gene border-left-orange">RET</span></li> <li><span class="gene">KRAS (incl. KRAS G12C)</span></li> <li><span class="gene border-left-purple">MET (incl. METex14 skipping)</span></li> <li><span class="gene border-left-red">ROS1</span></li> <li><span class="gene border-left-green">STK11</span></li> <li><span class="gene border-left-red">NTRK1</span></li> </ul> <p>&nbsp;</p> <h4>Alterations associated with:</h4> <p>An FDA-approved drug for another tumor type, inclusion or exclusion criteria for clinical trials and/or, indicators for resistance to therapy.</p> <p>&nbsp;</p> <ul class="newspaper-col-4 list-unstyled gene-list sm-2"> <li><span class="gene">AKT1</span></li> <li><span class="gene">CCND1</span></li> <li><span class="gene border-left-purple">CDKN2A</span></li> <li><span class="gene">CTNNB1</span></li> <li><span class="gene">ESR1</span></li> <li><span class="gene border-left-blue">FGFR1</span></li> <li><span class="gene">FGFR2</span></li> <li><span class="gene">FGFR3</span></li> <li><span class="gene">GATA3</span></li> <li><span class="gene">GNA11</span></li> <li><span class="gene">GNAQ</span></li> <li><span class="gene">GNAS</span></li> <li><span class="gene">HRAS</span></li> <li><span class="gene">IDH1</span></li> <li><span class="gene">IDH2</span></li> <li><span class="gene">KIT</span></li> <li><span class="gene">MAP2K1</span></li> <li><span class="gene">MYC</span></li> <li><span class="gene">NFE2L2</span></li> <li><span class="gene">NRAS</span></li> <li><span class="gene">NTRK3</span></li> <li><span class="gene">PDGFRA</span></li> <li><span class="gene">PIK3CA</span></li> <li><span class="gene">PPP2R1A</span></li> <li><span class="gene border-left-purple">PTEN</span></li> <li><span class="gene border-left-purple">TP53</span></li> <li><span class="gene">U2AF1</span></li> </ul> <p>&nbsp;</p> <p><span style="font-size:12px;"><strong>KEY:</strong></span></p> <ul class="newspaper-col-2 list-unstyled gene-list key sm-1"> <li><span style="font-size:12px;"><span class="gene">SNVs + Indels - Hotspot Regions</span></span></li> <li><span style="font-size:12px;"><span class="gene border-left-red">Fusion + SNVs + Indels</span></span></li> <li><span style="font-size:12px;"><span class="gene border-left-purple">CNVs + SNVs + Indels</span></span></li> <li><span style="font-size:12px;"><span class="gene border-left-orange">Fusions</span></span></li> <li><span style="font-size:12px;"><span class="gene border-left-blue">CNVs Only</span></span></li> <li><span style="font-size:12px;"><span class="gene border-left-green">SNVs + Indels - Exon Coverage:</span></span> <ul> <li><span style="font-size:10px;"><span class="gene border-left-green">70% of PTEN</span></span></li> <li><span style="font-size:10px;"><span class="gene border-left-green">88-100% for TP53, STK11 and CDKN2A</span></span></li> </ul> </li> </ul> </div> </div> </div> </div> </div> </div> <div id="" class="paragraph paragraph--type--content-highlight paragraph--view-mode--default"> <div class="highlight-section img-left"> <div id="highlight-id-750" class="media-wrap lazyload-bg" style="background-image: url('/sites/default/files/styles/lazy_load/public/2024-06/in-home-blood-draw.jpg?itok=B7RtQPro');" data-lazyload="/sites/default/files/2024-06/in-home-blood-draw.jpg"></div> <div class="highlight-content-wrap"> <div class="highlight-content"> <h4 class="highlight-title">Now Offering Site Location &amp; Mobile Phlebotomy Services</h4> <div class="highlight-body"><p>Providers: Fax or email an order to the patient advocate team at Fax: 239.690.4237, email <a href="mailto:patients@neogenomics.com">patients@neogenomics.com</a> to order site location or mobile phlebotomy services.</p> <p>Patients: call the patient advocate team at 866.776.5907 ext. 9 or email us at <a href="mailto:patients@neogenomics.com">patients@neogenomics.com</a> to schedule a site location testing appointment or in-home blood draw today.</p> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default"> <div id="" class="col-full padding-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p style="text-align: center;"><span style="font-size:12px;">In two prospective clinical validation studies* performed at 41 North American sites, 264 stage IIIB/IV NSCLC treatment-naïve patients who had blood collected within 12 weeks of tissue biopsy were recruited and tissue genotyping was performed when tissue was available (67% patients, n = 177): *NCT02906852 &amp; NCT03116633</span></p> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default corporate-pattern-bg"> <div id="" class="col-full padding-top-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><h4 id="sensitivity"><strong>Highly Sensitive &amp; Specific</strong></h4> <p>Accurately detect tumor mutations at very low levels in the blood</p> <p>InVisionFirst®-Lung analytical performance specifications for the 10 NSCLC actionable genes<sup>3</sup></p> <p>&nbsp;</p> <table border="0" cellpadding="1" cellspacing="1" class="table" style="width:100%;"> <thead> <tr> <th scope="col">&nbsp;</th> <th scope="col" style="text-align: center;">Detection Range</th> <th scope="col" style="text-align: center;">Variant Allele Fraction CNAR</th> <th scope="col" style="text-align: center;">Analytical Sensitivity</th> <th scope="col" style="text-align: center;">Analytical Specificity</th> </tr> </thead> <tbody> <tr> <td>SNVs</td> <td style="text-align: center;">≥0.10%</td> <td style="text-align: center;">0.25%<br> 0.06-0.08%</td> <td style="text-align: center;">95.0%<br> 93.0%</td> <td style="text-align: center;">100%</td> </tr> <tr> <td>Indels</td> <td style="text-align: center;">≥0.10%</td> <td style="text-align: center;">0.50%<br> 0.10%</td> <td style="text-align: center;">98.4%<br> 83.0%</td> <td style="text-align: center;">100%</td> </tr> <tr> <td>Fusions</td> <td style="text-align: center;">≥0.10%</td> <td style="text-align: center;">0.50%<br> 0.06%</td> <td style="text-align: center;">96.2%<br> 77.5%</td> <td style="text-align: center;">100%</td> </tr> <tr> <td>CNVs</td> <td style="text-align: center;">≥1.25X</td> <td style="text-align: center;">≥1.5X<br> ≥1.25X</td> <td style="text-align: center;">98.3%<br> 86.0%</td> <td style="text-align: center;">100%</td> </tr> </tbody> <tfoot> <tr> <td colspan="5"><em><small>CNAR: Copy Number Amplification Ratio</small></em></td> </tr> </tfoot> </table> </div> </div> </div> </div> </div> </div> <div id="" class="paragraph paragraph--type--cards paragraph--view-mode--default"> <div class="cards-section"> <div class="cards-content"> <div class="content-wrap"> <div class="field field--name-field-cards field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="field field--name-field-title field--type-string field--label-hidden field__item">At Diagnosis</div> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>When results from EGFR single nucleotide variants (SNVs) and insertion and deletions (indels); rearrangements in ALK, NTRK1, RET and ROS1; and SNVs for BRAF are not available<br> AND<br> When tissue-based CGP is infeasible (i.e. quantity not sufficient (QNS) for tissue-based CGP or invasive biopsy is medically contraindicated).</p> </div> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--card paragraph--view-mode--default"> <div class="field field--name-field-title field--type-string field--label-hidden field__item">At Progression</div> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>For patients progressing on or after chemotherapy or immunotherapy who have not been tested for EGFR SNVs and indels; rearrangements in ALK, NTRK1, RET and ROS1; and SNVs for BRAFs, and for whom tissue-based CGP is infeasible;<br> OR<br> For patients progressing on EGFR tyrosine kinase inhibitors&nbsp;(TKIs).</p> </div> </div> </div> </div> </div> <div id="paragraph-id-745" class="media-wrap lazyload-bg" style="background-image: url('/sites/default/files/styles/lazy_load/public/2021-07/Blood_cells_cards.png?itok=F_abo0tM');" data-lazyload="/sites/default/files/2021-07/Blood_cells_cards.png"></div> </div> </div> </div> <div class="paragraph paragraph--type--columns paragraph--view-mode--default"> <div id="" class="col-full padding-top-bottom-100"> <div class="field field--name-field-column-content field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--wysiwyg paragraph--view-mode--default"> <div class="clearfix text-formatted field field--name-field-body field--type-text-long field--label-hidden field__item"><p>References:</p> <ol> <li>Rolfo, et al. Journal of Thoracic Oncology.2021; doi.org/10.1016/j.jtho.2021.06.017. doi:10.1200/po.18.00299 (2019).</li> <li>VanderLaan PA, et al. Cancer Cytopathol. 2021;129(3):179-181</li> <li>Plagnol, V. et al.PloS one 13, e0193802, doi:10.1371/journal.pone.0193802(2018).</li> </ol> <p>&nbsp;</p> <p class="disclaimer">*Turnaround time is 7 days when samples are sent directly to Research Triangle Park (RTP) for processing.</p> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--block-reference paragraph--view-mode--default"> <div class="field field--name-field-block-reference field--type-block-field field--label-hidden field__item"><div id="block-genericcontactcta" class="block block-block-content block-block-content8a55c531-c994-47e1-876c-0677143882c7 block--full-width-cta"> <div class="cta-content-wrap"> <div class="cta-content"> <h4 class="field--name-field-title">Contact Us To Get Started!</h4> <p class="field--name-field-body-unformatted">Work with us – your premier oncology partner – to optimize cancer care for patients</p> <div class="field--name-field-link"> <a href="/contact-us" 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