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<span class="site-header__logo"> <a href="https://www.massgeneral.org">Massachusetts General Hospital</a> </span> <div class="nav__primary__item -search mobile__search-toggle"> <button id="mobile__search-trigger" data-nav="trigger"> <span class="a11y-sr-only">Search</span> </button> </div> <button class="site-nav__toggle" aria-controls="site-navigation" aria-haspopup="true" aria-expanded="false" data-module="nav-toggle"> <span class="a11y-sr-only">Menu</span> </button> </div> <div class="site-header__sub-block" data-header="sub"> <p class="site-header__tagline"> <a href="/default.aspx">Advances in <i>Motion</i></a> </p> </div> <nav aria-label="Main navigation" class="site-nav" id="site-navigation"> <ul class="nav__utility" role="presentation"> <li><a href="/event-education-listing.aspx">Education & Training</a></li> <li><a href="/clinical-trial-listing.aspx">Clinical Trials</a></li> <li><a href="https://www.massgeneral.org/appointments-and-referrals/referral-request">Refer a 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-padding--vertical -border--bottom--tablet-up"> <div class="content-container -width--narrow -centered"> <p class="lede u-text-centered"> Advances in Motion provides health care professionals with information about the latest breakthroughs, research and clinical advances from Massachusetts General Hospital.</p> <p class="featured-links -width--xnarrow"> <a class="featured-link" href="/specialty-listing.aspx">EXPLORE OUR SPECIALTIES</a> <i class="featured-link__separator"></i> <a class="featured-link" href="/topic-listing.aspx">BROWSE OUR TOPICS</a> <i class="featured-link__separator"></i> <a class="featured-link" href="https://pages.connect.massgeneral.org/subscription-center-med-prof.html">SUBSCRIBE TO RECEIVE UPDATES</a> </p> </div> </div> </section> <section class="-padding--horizontal -padding--vertical"> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__pod--half"> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__image"> <a href="/neuro/article.aspx?id=1570"> <img itemprop="image" srcset="/neuro/assets/neuro_homepage_restless-leg-syndrome_advances.jpg, /neuro/assets/neuro_homepage_restless-leg-syndrome_advancesx2.jpg" src="/neuro/assets/neuro_homepage_restless-leg-syndrome_advances.jpg"> </a> </p> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/neuro/specialty.aspx?id=1004">In Neuroscience</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/article.aspx?id=1570" itemprop="url">New Website Allows Provider Consultations for Patients With Restless Leg Syndrome</a> </h3> <p itemprop="description"> A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives. </p> <p class="content-tease__related"> <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a>, <a href="/neuro/topic.aspx?id=1017" itemprop="relatedLink">Psychiatry</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-04-29" itemprop="datePublished">April 29, 2024</time> </p> </div> </div> <div class="layout-columns__pod--half"> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__image"> <a href="/otolaryngology/article.aspx?id=1574"> <img itemprop="image" srcset="/otolaryngology/assets/homepage_ent_toth-center_advances.jpg, /otolaryngology/assets/homepage_ent_toth-center_advancesx2.jpg" src="/otolaryngology/assets/homepage_ent_toth-center_advances.jpg"> </a> </p> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/otolaryngology/specialty.aspx?id=1016">In Otolaryngology</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/otolaryngology/article.aspx?id=1574" itemprop="url">The Toth Center: New Leadership, Novel Innovations</a> </h3> <p itemprop="description"> Scientists are working towards new, innovative approaches to faster and more accurate diagnoses, less invasive treatments, predictive medicine, and more. With new leadership and collaborations, the Toth Center at Mass Eye and Ear is making great headway for the future of head and neck cancer care. </p> <p class="content-tease__related"> <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a>, <a href="/otolaryngology/specialty.aspx?id=1016" itemprop="relatedLink">Otolaryngology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-06-18" itemprop="datePublished">June 18, 2024</time> </p> </div> </div> </div> </section> <section class="-padding--horizontal -padding--vertical"> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__pod--third"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/ortho/specialty.aspx?id=1003">In Orthopaedics</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/ortho/journal.aspx?id=2628" itemprop="url">First AI Model Developed for Diagnosis of Hip Dysplasia From Plain Radiographs</a> </h3> <p itemprop="description"> <span>Martin Magn&eacute;li, MD, PhD, Orhun Muratoglu, PhD, and colleagues have developed two convolutional neural networks that can read plain radiographs and classify hips as dysplastic or non-dysplastic with 83% to 92% accuracy, and detect the severity of hip dysplasia based on the Crowe or Hartofilakidis classifications.</span> </p> <p class="content-tease__related"> <a href="/research-and-innovation/topic.aspx?id=1111" itemprop="relatedLink">Artificial Intelligence</a>, <a href="/ortho/topic.aspx?id=1007" itemprop="relatedLink">Hip and Knee</a>, <a href="/ortho/specialty.aspx?id=1003" itemprop="relatedLink">Orthopaedics</a>, <a href="/radiology/specialty.aspx?id=1013" itemprop="relatedLink">Radiology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-06-03" itemprop="datePublished">June 3, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/oncology/specialty.aspx?id=1008">In Oncology</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/oncology/article.aspx?id=1566" itemprop="url">Revolutionizing Cancer Immunotherapy for Melanoma and Beyond</a> </h3> <p itemprop="description"> Researchers at Massachusetts General Hospital won a Breakthrough Award to enhance personalized approaches to immunotherapy for metastatic melanoma. </p> <p class="content-tease__related"> <a href="/oncology/topic.aspx?id=1081" itemprop="relatedLink">Immunotherapy</a>, <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-04-09" itemprop="datePublished">April 9, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> <p class="content-tease__topic"> <span class="highlight">Featured</span> <a href="/obgyn/specialty.aspx?id=1006">In OB/GYN</a> </p> <h3 class="content-tease__heading" itemprop="name"> <a href="/obgyn/journal.aspx?id=2626" itemprop="url">Single-Step Blastocyst Warming Validated, Saves Time Without Compromising Outcomes</a> </h3> <p itemprop="description"> <span>Victoria S. Jiang, MD, Charles L. Bormann, PhD, and colleagues found that compared with standard blastocyst warming, a simpler protocol that removes at least 15 minutes from warming time yields similar rates of implantation, clinical pregnancy, spontaneous abortion, and live birth as well as similar birth weight.</span> </p> <p class="content-tease__related"> <a href="/obgyn/topic.aspx?id=1047" itemprop="relatedLink">Fertility</a>, <a href="/obgyn/specialty.aspx?id=1006" itemprop="relatedLink">OB/GYN</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-05-29" itemprop="datePublished">May 29, 2024</time> </p> </div> </div> </div> </section> <section class="-padding--vertical -padding--horizontal -background--grey" style="background-image: url(/assets/images/home-latest-bg.jpg);"> <div class="content-container -width--wide -centered -padding--bottom"> <h2 class="u-text-centered heading-h3">The Latest Digestive Health Advances</h2> </div> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__main"> <div class="layout-columns__main__content"> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/digestive-health/article-external.aspx?id=1169" itemprop="url"> Taking Aspirin Associated With Reduction in Colorectal Cancer Among High-Risk Population</a> </h3> <p itemprop="description"> <p>Massachusetts General Hospital researchers found that regular aspirin use was associated with the greatest reduction of colorectal cancer among those at the highest risk.</p></p> <p class="content-tease__related"> <a href="/oncology/topic.aspx?id=1059" itemprop="relatedLink">Colorectal Cancer</a>, <a href="/digestive-health/specialty.aspx?id=1007" itemprop="relatedLink">Digestive Health</a>, <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-09-11" itemprop="datePublished">September 11, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/digestive-health/journal.aspx?id=2641" itemprop="url"> Cholesterol-reducing Gut Bacteria Might Lower Heart Disease Risk</a> </h3> <p itemprop="description"> <p>Ramnik J. Xavier, MD, PhD,&nbsp;Chenhao&nbsp;Li, PhD, Martin Stražar, PhD, and colleagues have found that cholesterol metabolism is an important property of certain gut bacteria, Oscillibacter, with potential benefits for lipid homeostasis and cardiovascular health.</p></p> <p class="content-tease__related"> <a href="/cardiovascular/specialty.aspx?id=1002" itemprop="relatedLink">Cardiovascular</a>, <a href="/digestive-health/specialty.aspx?id=1007" itemprop="relatedLink">Digestive Health</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-08-05" itemprop="datePublished">August 5, 2024</time> </p> </div> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret -large" href="/digestive-health/specialty.aspx?id=1007">View all Digestive Health Updates</a> </p> </div> </div> <div class="layout-columns__sidebar"> <div class="layout-columns__sidebar__content"> <div class="profile-compact__wrapper"> <p class="u-no-margin"> <strong>Contributing Physicians</strong> </p> <div class="profile -compact" itemscope itemtype="http://schema.org/Person"> <div class="profile__content"> <h3 class="profile__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1329" itemprop="url">Ashwin N. Ananthakrishnan, MBBS, MPH</a></h3> <p class="profile__title" itemprop="jobTitle">Director of the Crohn's and Colitis Center, Division of Gastroenterology, Mass General, Associate Professor of Medicine, Harvard Medical School </p> </div> <p class="profile__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/ashwin_ananthakrishan_advances.png, /assets/images/contributors/ashwin_ananthakrishan_advances_2x.png 2x" src="/assets/images/contributors/ashwin_ananthakrishan_advances.png"> </p> </div> <div class="profile -compact" itemscope itemtype="http://schema.org/Person"> <div class="profile__content"> <h3 class="profile__name" itemprop="name"> <a href="/contributors/contributor.aspx?id=1328" itemprop="url">Ramnik Joseph Xavier, MD, PhD</a></h3> <p class="profile__title" itemprop="jobTitle">Director, Center for the Study of Inflammatory Bowel Disease, Kurt J. Isselbacher Professor of Medicine in the Field of Gastroenterology, Harvard Medical School</p> </div> <p class="profile__image"> <img alt="" itemprop="image" srcset="/assets/images/contributors/xavier_ramnik_advances.png, /assets/images/contributors/xavier_ramnik_advances_2x.png 2x" src="/assets/images/contributors/xavier_ramnik_advances.png"> </p> </div> </div> </div> </div> </div> </section> <section class="-padding--vertical -padding--horizontal"> <div class="content-container -width--wide -centered -padding--bottom -border--bottom--tablet-up"> <h2 class="section-heading -centered">Advances Specialties</h2> <div class="layout-columns -width--wide -centered" data-module="equal-heights" data-columns=".layout-columns__pod--third" data-rows=".content-tease"> <div class="layout-columns__pod--third -padding--bottom"> <h3 class="content-tease__heading -large"> <a href="/neuro/specialty.aspx?id=1004">Neuroscience</a> </h3> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/article-external.aspx?id=1170" itemprop="url"> Fish Oil May Reduce Risk of Alzheimer's Disease in High-Risk Population</a> </h3> <p itemprop="description"> <p>A study published in JAMA Network Open evaluated 102 people aged 75 and up who had lower levels of omega-3 fatty acids, a key ingredient in fish oil. Fish oil supplements are thought to improve brain function for people with memory issues.</p></p> <p class="content-tease__related"> <a href="/neuro/topic.aspx?id=1038" itemprop="relatedLink">Alzheimer's Disease</a>, <a href="/neuro/topic.aspx?id=1018" itemprop="relatedLink">Neurology</a>, <a href="/neuro/specialty.aspx?id=1004" itemprop="relatedLink">Neuroscience</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-10-01" itemprop="datePublished">October 1, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/journal.aspx?id=2646" itemprop="url"> Propensity Score Weighting Accounts Well for Placebo Response in Two Trials of Medical Therapy for MDD</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-09-10" itemprop="datePublished">September 10, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/neuro/q-a.aspx?id=1029" itemprop="url"> Insights on Substance Use Disorder Treatment and Stigma Reduction: Q&A With Sarah Wakeman, MD</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -qa">Q & A</span> <time class="date" datetime="2024-09-04" itemprop="datePublished">September 4, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third -padding--bottom"> <h3 class="content-tease__heading -large"> <a href="/pulmonary/specialty.aspx?id=1012">Pulmonary and Critical Care</a> </h3> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/endocrinology/article-external.aspx?id=1168" itemprop="url"> Bionic Pancreas Improves Glycemic Control in Patients With Cystic Fibrosis-related Diabetes</a> </h3> <p itemprop="description"> <p>Melissa Putman, MD, Jordan Sherwood, MD, and colleagues report that the insulin-only iLet bionic pancreas improved glucose control in patients with cystic fibrosis-related diabetes (CFRD) compared to usual care, without an increase in continuous glucose monitoring-measured hypoglycemia.</p></p> <p class="content-tease__related"> <a href="/endocrinology/topic.aspx?id=1105" itemprop="relatedLink">Diabetes</a>, <a href="/endocrinology/specialty.aspx?id=1015" itemprop="relatedLink">Endocrinology</a>, <a href="/pulmonary/specialty.aspx?id=1012" itemprop="relatedLink">Pulmonary and Critical Care</a> </p> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-08-14" itemprop="datePublished">August 14, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/pulmonary/article.aspx?id=1577" itemprop="url"> Transforming the Future of Lung Transplantation by Improving Access and Outcomes</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -article">Article</span> <time class="date" datetime="2024-07-02" itemprop="datePublished">July 2, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/pulmonary/journal.aspx?id=2625" itemprop="url"> Endobronchial Optical Coherence Tomography May Identify Pre-Symptomatic Disease Amongst Patients With Interstitial Lung Abnormalities</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-05-28" itemprop="datePublished">May 28, 2024</time> </p> </div> </div> <div class="layout-columns__pod--third -padding--bottom"> <h3 class="content-tease__heading -large"> <a href="/urology/specialty.aspx?id=1005">Urology</a> </h3> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/urology/journal.aspx?id=2632" itemprop="url"> Multiparametric MRI Is Often False-Negative for Clinically Significant Prostate Cancer</a> </h3> <p itemprop="description"> <p><span>Chin-Lee Wu, MD, PhD, Douglas M. Dahl, MD, and colleagues found that 15% of patients who had negative prostate multiparametric MRI (mpMRI) were diagnosed by 20-core standard template biopsy as having clinically significant prostate cancer. They recommend considering standard biopsy regardless of negative mpMRI.</span></p></p> <p class="content-tease__related"> <a href="/oncology/specialty.aspx?id=1008" itemprop="relatedLink">Oncology</a>, <a href="/oncology/topic.aspx?id=1065" itemprop="relatedLink">Prostate Cancer</a>, <a href="/urology/specialty.aspx?id=1005" itemprop="relatedLink">Urology</a> </p> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-06-28" itemprop="datePublished">June 28, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/urology/journal.aspx?id=2621" itemprop="url"> Potential Strategy Identified for Treating Bone-Metastatic Clear Cell RCC</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-05-14" itemprop="datePublished">May 14, 2024</time> </p> </div> <div class="content-tease -border--bottom" itemscope itemtype="http://schema.org/ScholarlyArticle"> <h3 class="content-tease__heading" itemprop="name"> <a href="/urology/journal.aspx?id=2601" itemprop="url"> Less Aggressive Protocol Suitable for Muscle-invasive Bladder Cancer in Noncystectomy Candidates</a> </h3> <p class="content-metadata"> <span class="content-metadata__media -journal">Journal</span> <time class="date" datetime="2024-03-13" itemprop="datePublished">March 13, 2024</time> </p> </div> </div> </div> <p class="fat-link__wrapper u-no-margin u-text-centered"> <a class="fat-link -caret -large" href="/specialty-listing.aspx">View All Specialties</a> </p> </div> </section> <section class="topics-layout -no-border"> <div class="topics-layout__inner"> <div class="topics-layout__sidebar"> <h2 class="section-heading">Trending topics</h2> </div> <div class="topics-layout__main"> <ul class="topics-list" 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<div class="layout-columns"> <div class="layout-columns__pod--half"> <div class="content-tease" itemscope itemtype="http://schema.org/Event"> <p class="content-tease__topic -large"> May 31, 2024 - June 4, 2024</p> <h3 class="content-tease__heading" itemprop="name"> <a href="/oncology/event.aspx?id=1065" itemprop="url"> Conference: ASCO 2024 Annual Meeting</a> </h3> <p class="content-metadata -border-bottom"> Conference</p> <p itemprop="description"> Leaders from the Mass General Cancer Center will present groundbreaking cancer research at this year’s ASCO 2024 Annual Meeting, held May 31 – June 4, 2024, both in-person in Chicago, IL, and virtually.</p> </div> </div> <div class="layout-columns__pod--half"> <div class="content-tease" itemscope itemtype="http://schema.org/Event"> <p class="content-tease__topic -large"> May 16-19, 2024</p> <h3 class="content-tease__heading" itemprop="name"> <a href="/cardiovascular/event.aspx?id=1083" itemprop="url"> Conference: Heart Rhythm 2024</a> </h3> <p class="content-metadata -border-bottom"> Conference</p> <p itemprop="description"> Massachusetts General Hospital faculty will join the global electrophysiology community at Heart Rhythm 2024, an annual meeting and educational program hosted by the Heart Rhythm Society on May 16 - 19, 2024 in Boston, MA.</p> </div> </div> </div> <p class="fat-link__wrapper u-text-right"> <a class="fat-link -caret" href="/event-education-listing.aspx">View All</a> </p> </div> </div> </div> <div class="layout-columns -width--wide -centered"> <div class="layout-columns__sidebar"> <div class="layout-columns__sidebar__content -padding--horizontal -padding--bottom"> <h2 class="section-heading">Clinical Trials</h2> </div> </div> <div class="layout-columns__main"> <div class="layout-columns__main__content -padding--horizontal -padding--vertical--tablet-up"> <div class="layout-columns"> <div class="layout-columns__pod--half"> <div class="content-tease" itemscope itemtype="http://schema.org/ScholarlyArticle"> 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