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data-renderer="svg" data-default-duration="0" data-duration="6"></div></div></div></div></section><div data-w-id="b3d5d6fe-d82b-24bd-3da0-e6be2ec1e183" class="sections-wrapper"><section class="main-content_section grey"><div class="padding-home_section overflow-hidden"><div class="container-grid_main two-column-even center"><div id="w-node-_78a03044-b1e5-6774-e495-d97692bbc90c-206805d1" class="content_wrap mobile"><h3 class="section-main_heading">AI-powered Clinical Trial Design for <span class="light serif">Key Studies</span></h3><div class="padding-xxsmall"></div><a href="https://portal.unlearn.ai/overview" target="_blank" class="button purple w-button">Try TrialPioneer</a><div class="padding-xxsmall"></div></div><div id="w-node-a9f8b267-da0b-4e1b-0bf6-fc0b104c4d9c-206805d1" class="grid-column_wrapper no-space"><div class="content_wrap desktop"><h3 class="section-main_heading">AI-powered Clinical Trial Design for <span class="light serif">Key Studies</span></h3><div class="padding-xxsmall"></div><a href="https://portal.unlearn.ai/overview" target="_blank" class="button purple w-button">Try TrialPioneer</a><div class="padding-small"></div></div><div class="content_wrap"><div class="accordians_wrapper"><div class="accordian-container first"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">01.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Phase 2 and 3 Studies</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">Design smaller, faster, highly-powered randomized trials that leverage digital twins to reduce sample sizes without sacrificing power. Alternatively, use digital twins to boost trial power without adding additional trial participants. This approach is qualified by the EMA and aligns with current FDA guidance.</p><div class="padding-xsmall"></div></div></div><div class="accordian-container second"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">02.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Single-Arm Studies</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">Generate digital twins as a simulated control group in single-arm studies, enabling precise treatment effect analysis for the trial. This provides a robust comparator group without needing a traditional or externally matched control arm.</p><div class="padding-xsmall"></div></div></div><div class="accordian-container third"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">03.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Multiple Ascending Dose (MAD) Studies</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">Design a MAD study using digital twins to accelerate the timeline for determining the safety, tolerability, and optimal dose ranges, allowing for quicker progression to later trial phases or go/no-go decisions.</p><div class="padding-xsmall"></div></div></div></div></div></div><div id="dont-swap" class="accordian-images-wrapper auto-height w-node-a9f8b267-da0b-4e1b-0bf6-fc0b104c4de9-206805d1"><div class="accordian-item-container"><div class="accordian-animation-wrapper first"><div class="dashboard_wrapper"><img src="https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671fd6f2350c574782f845c6_platform-1d.png" loading="lazy" sizes="(max-width: 479px) 85vw, (max-width: 767px) 91vw, (max-width: 991px) 96vw, 50vw" srcset="https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671fd6f2350c574782f845c6_platform-1d-p-500.png 500w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671fd6f2350c574782f845c6_platform-1d-p-800.png 800w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671fd6f2350c574782f845c6_platform-1d-p-1080.png 1080w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671fd6f2350c574782f845c6_platform-1d-p-1600.png 1600w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671fd6f2350c574782f845c6_platform-1d-p-2000.png 2000w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671fd6f2350c574782f845c6_platform-1d.png 2360w" alt="" class="dashboard-image"/></div></div></div></div></div></div></section><section class="main-content_section"><div class="padding-home_section overflow-hidden"><div class="container-grid_main two-column-even center"><div id="w-node-_18721762-da23-8c6d-ed2a-359bbde41bb5-206805d1" class="content_wrap mobile"><h3 class="section-main_heading">Gain Predictive Trial Insights with the <span class="light serif">Digital Twins Dashboard</span></h3><div class="padding-small"></div></div><div id="w-node-a133fac3-586b-323d-e520-e33626075159-206805d1" class="grid-column_wrapper no-space"><div class="content_wrap desktop"><h3 class="section-main_heading">Gain Predictive Trial Insights with the <span class="light serif">Digital Twins Dashboard</span></h3><div class="padding-small"></div></div><div class="content_wrap"><div class="accordians_wrapper"><div class="accordian-container first"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">01.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Explore predicted outcomes</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">For any participant or subgroup across all measured clinical variables – outcomes, biomarkers, labs, and vital – at any point in time.</p><div class="padding-xsmall"></div></div></div><div class="accordian-container second"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">02.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Gain real-time insights</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">About expected progression as participants enroll and make more informed, data-driven decision-making throughout the trial.</p><div class="padding-xsmall"></div></div></div><div class="accordian-container third"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">03.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Identify sensitive clinical outcomes</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">To optimize composite scores for better signal detection. This enhances the sensitivity of outcomes at both the population and subpopulation levels, offering insight into meaningful clinical outcomes for your trial population.</p><div class="padding-xsmall"></div></div></div></div></div></div><div id="dont-swap" class="accordian-images-wrapper auto-height w-node-a133fac3-586b-323d-e520-e33626075192-206805d1"><div class="accordian-item-container alt"><div class="accordian-animation-wrapper first"><div class="dashboard_wrapper second"><img src="https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671faced883fde668bbcfc95_platform-2b.png" loading="lazy" sizes="(max-width: 479px) 85vw, (max-width: 767px) 91vw, (max-width: 991px) 93vw, 49vw" srcset="https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671faced883fde668bbcfc95_platform-2b-p-500.png 500w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671faced883fde668bbcfc95_platform-2b-p-800.png 800w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671faced883fde668bbcfc95_platform-2b-p-1080.png 1080w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671faced883fde668bbcfc95_platform-2b-p-1600.png 1600w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671faced883fde668bbcfc95_platform-2b-p-2000.png 2000w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/671faced883fde668bbcfc95_platform-2b.png 2360w" alt="" class="dashboard-image"/></div></div></div></div></div></div></section><section class="main-content_section grey"><div class="padding-home_section overflow-hidden"><div class="container-grid_main two-column-even center"><div id="w-node-_1dbf6ae3-ecdc-a1d0-cefe-06888980ec23-206805d1" class="content_wrap mobile"><h3 class="section-main_heading">Maximize Precision and Power in Trial Analysis with <span class="light serif">Digital Twins</span></h3><div class="padding-small"></div></div><div id="w-node-a9a61b8e-0852-b4e3-5c4b-f8162d88e740-206805d1" class="grid-column_wrapper no-space"><div class="content_wrap desktop"><h3 class="section-main_heading">Maximize Precision and Power in Trial Analysis with <span class="light serif">Digital Twins</span></h3><div class="padding-small"></div></div><div class="content_wrap"><div class="accordians_wrapper"><div class="accordian-container first"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">01.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Obtain precise treatment effect estimates</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">For all variables at any time, for the full trial population, and in predefined subgroups.</p><div class="padding-xsmall"></div></div></div><div class="accordian-container second"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">02.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Boost statistical power for confident decision-making</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">Whether at interim stages or end of study. Achieve greater confidence in assessing drug effectiveness, reducing uncertainty, and enabling more informed decision-making.</p><div class="padding-xsmall"></div></div></div><div class="accordian-container third"><div class="accordian-heading_wrapper"><div class="accordian-progress-container"><div class="accordian-progress-bar"></div></div><div class="padding-xsmall"></div><div class="accordian-content"><div class="accordian-count">03.</div><div class="accordian-inner-content"><h4 class="accordian-content-heading">Discover responder subpopulations for targeted treatment</h4></div></div><div class="padding-xsmall"></div></div><div class="accordian-content-container"><p class="p-small">To identify likely responder individuals and subpopulations. Unlock valuable insights into the patients who benefit the most from the treatment.</p><div class="padding-xsmall"></div></div></div></div></div></div><div id="dont-swap" class="accordian-images-wrapper auto-height w-node-a9a61b8e-0852-b4e3-5c4b-f8162d88e779-206805d1"><div class="accordian-item-container"><div class="accordian-animation-wrapper first"><div class="dashboard_wrapper"><img src="https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/67202162c540296b1f41c824_platform-3d.png" loading="lazy" sizes="(max-width: 479px) 85vw, (max-width: 767px) 91vw, (max-width: 991px) 96vw, 50vw" srcset="https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/67202162c540296b1f41c824_platform-3d-p-500.png 500w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/67202162c540296b1f41c824_platform-3d-p-800.png 800w, https://cdn.prod.website-files.com/66fc2ff3074bb309fb4d56fc/67202162c540296b1f41c824_platform-3d-p-1080.png 1080w, 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