CINXE.COM
ZOSYN (piperacillin and tazobactam injection) is available with one point of contact from Baxter
<!DOCTYPE html> <html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#" class="no-js"> <head> <meta charset="utf-8" /> <meta name="description" content="Zosyn is a combination of piperacillin, a penicillin-class antibacterial and tazobactam, a beta-lactamase inhibitor, indicated for the treatment of intra-abdominal infections in adult and pediatric patients 2 months of age and older, nosocomial pneumonia in adult and pediatric patients 2 months of age and older, skin and skin structure infections in adults, female pelvic infections in adults, and community-acquired pneumonia in adults" /> <link rel="canonical" href="https://ushospitalproducts.baxter.com/zosyn-premix-for-injection" /> <meta property="og:site_name" content="Hospital Care" /> <meta property="og:url" content="https://ushospitalproducts.baxter.com/zosyn-premix-for-injection" /> <meta property="og:title" content="A Homecoming — ZOSYN (piperacillin and tazobactam) Injection" /> <meta property="og:image:url" content="https://ushospitalproducts.baxter.com/sites/g/files/ebysai2186/files/styles/long_image/public/2023-04/Zosyn_LandingPage_Rv8_NewHeader.png?itok=ES3l6ejk" /> <meta property="og:image:type" content="image/png" /> <meta property="og:image:width" content="1600" /> <meta property="og:image:height" content="417" /> <meta property="og:image:alt" content="The first and only ZOSYN premix piperacillin and tazobactam is available from Baxter with one point of contact." /> <meta name="twitter:card" content="summary_large_image" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <link rel="alternate" hreflang="en" href="https://ushospitalproducts.baxter.com/zosyn-premix-for-injection" /> <link rel="icon" href="/core/misc/favicon.ico" type="image/vnd.microsoft.icon" /> <script src="/sites/g/files/ebysai2186/files/google_tag/ati/google_tag.script.js?snbfdk" defer></script> <title>ZOSYN (piperacillin and tazobactam injection) is available with one point of contact from Baxter</title> <link rel="preload" href="/profiles/custom/bax_base/themes/bax_base_theme/build/fonts/roboto/roboto-regular.woff2" as="font" type="font/woff2" crossorigin="anonymous"> <link rel="preload" href="/profiles/custom/bax_base/themes/bax_base_theme/build/fonts/geogrotesque/36876D_0_0.woff2" as="font" type="font/woff2" crossorigin="anonymous"> <link rel="preload" href="/profiles/custom/bax_base/themes/bax_base_theme/build/fonts/geogrotesque/367E70_0_0.woff2" as="font" type="font/woff2" crossorigin="anonymous"> <link rel="preload" href="/profiles/custom/bax_base/themes/bax_base_theme/build/fonts/geogrotesque/368766_0_0.woff2" as="font" type="font/woff2" crossorigin="anonymous"> <link rel="preload" href="/profiles/custom/bax_base/themes/bax_base_theme/build/fonts/icomoon/icomoon.woff2" as="font" type="font/woff2" crossorigin="anonymous"> <script> // If fonts are cached, skip FFO. if (sessionStorage.fontsLoaded === 'true') { document.documentElement.classList.add('fonts-loaded'); } else { var script = document.createElement('script'); script.src = "/profiles/custom/bax_base/themes/bax_base_theme/build/scripts/fontloader.built.js"; script.async = true; document.head.appendChild(script); } </script> <link rel="stylesheet" media="all" href="/sites/g/files/ebysai2186/files/css/css_mBxHYtNjjz0TriDV-emB5nfQUI2J-CQ3TKQ_TiNEyAc.css?delta=0&language=en&theme=bax_specialty_theme&include=eJxtzlEKwjAQBNALtc2RwqRZk-i2G7IbMbcXBS1U_4Z5MEyEgTGouUAZ9yJNJ7kZfIKRX2W3JuxYknSbdKjR5gKUpoCHfwVvmTZyV50vIkbtDIklgGe1wWVPP2rbHD8X3qiV1gK28Xf4rKd1NVhRK6u62HoFL0czVTSkhpq_eDRL32sPXDRTfAIqU2xC" /> <link rel="stylesheet" media="all" href="/sites/g/files/ebysai2186/files/css/css_fOnOlRO0KbMPAQGTLV4etpufwBXGACRbPJhjrICTl7I.css?delta=1&language=en&theme=bax_specialty_theme&include=eJxtzlEKwjAQBNALtc2RwqRZk-i2G7IbMbcXBS1U_4Z5MEyEgTGouUAZ9yJNJ7kZfIKRX2W3JuxYknSbdKjR5gKUpoCHfwVvmTZyV50vIkbtDIklgGe1wWVPP2rbHD8X3qiV1gK28Xf4rKd1NVhRK6u62HoFL0czVTSkhpq_eDRL32sPXDRTfAIqU2xC" /> <link rel="shortcut icon" href="/profiles/custom/bax_base/themes/bax_base_theme/build/favicon.ico"> <link rel="apple-touch-icon" sizes="180x180" href="/profiles/custom/bax_base/themes/bax_base_theme/build/apple-touch-icon.png"> <link rel="icon" type="image/png" sizes="32x32" href="/profiles/custom/bax_base/themes/bax_base_theme/build/favicon-32x32.png"> <link rel="icon" type="image/png" sizes="16x16" href="/profiles/custom/bax_base/themes/bax_base_theme/build/favicon-16x16.png"> <link rel="manifest" href="/profiles/custom/bax_base/themes/bax_base_theme/build/site.webmanifest"> <link rel="mask-icon" href="/profiles/custom/bax_base/themes/bax_base_theme/build/safari-pinned-tab.svg" color="#154898"> <meta name="msapplication-TileColor" content="#154898"> <meta name="msapplication-config" content="/profiles/custom/bax_base/themes/bax_base_theme/build/browserconfig.xml"> <meta name="theme-color" content="#154898"> <link rel="dns-prefetch" href="//players.brightcove.com"> <link rel="dns-prefetch" href="//c.brightcove.com"> <link rel="dns-prefetch" href="//edge.api.brightcove.com"> <link rel="dns-prefetch" href="//f1.media.brightcove.com"> <link rel="dns-prefetch" href="//vjs.zencdn.net"> <link rel="dns-prefetch" href="//www.googletagmanager.com"> </head> <body class="path-node page-node-type-specialty-product-detail"> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-TCH4G84" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <ul class="skip" data-module="SkipLink"> <li> <a href="#main-content"> Skip to main content </a> </li> </ul> <header class="global-header global-header--specialty"> <div class="nav-top-bar"> <div class="nav-top-bar__content"> <a class="nav-top-bar__ext-link arrow-link" href="https://www.baxter.com">Explore baxter.com <span class="icon icon-external-link"></span></a> <div class="nav-top-bar__text"> <p class="disclaimer">This site is intended for US healthcare professionals</p> <a href="#isi" class="isi-link">Important Safety Information</a> </div> </div> </div> <div class="nav-utility-bar"> <div class="nav-utility-bar__content"> <div class="baxter-logo"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 232 42"><style>.baxter-logo{fill:#fff;}</style><path class="baxter-logo" d="M137.7 5.6l14.1-1-1.6 6.6h11.4l-1.3 5.3h-11.5s-4 16.2-4.1 16.7c-.5 2.1.4 3.7 2.6 3.7h7.4c1.3 0 2.7-.8 2.7-.8l-1.6 6H138c-1.7 0-8.9-1.6-6.7-10.8 2.2-9.3 6.4-25.7 6.4-25.7M186.4 19.4c-.3 1.8-.9 4.3-.9 4.3h-9.6s1-4.2 1.2-4.7c.4-1.3.7-2.5 2.5-2.5h4.6c1.5-.1 2.5 1.4 2.2 2.9m5.5-8.1h-20.7c-6.6 0-7.8 7.1-7.8 7.1s-1.2 4.7-3.3 13.8c-1.8 7.7 4 9.8 7.5 9.8h25.9l2.5-5.9s-1.5.8-3 .8h-17c-2.8 0-3-2.2-2.6-3.9.1-.4 1-3.9 1-3.9h23.2l2.1-9c1.2-9.2-7.8-8.8-7.8-8.8M204.3 14.8s-4.4 18.5-5.6 23c-.6 2.3-2.1 4.2-2.1 4.2h16.2c-.4-1-.5-2.6-.1-4.2.3-1.1 3.4-14.6 3.9-17.2.5-2.5 3-2.3 3-2.3h7.4c1.6 0 2.8 1.2 2.8 1.2l2.3-8.2h-9.8c-4 0-5.2 4.1-5.2 4.1v-4.1h-13c.5 1.3.2 3.5.2 3.5M95 13c.1.2 8.7 15.9 8.7 15.9L86.9 42h8.6l10.4-8.1s2.5 4.7 3 5.6c.4 1 .7 2.4.7 2.4h17.1s-.8-.6-1.5-1.9c-.2-.4-8.1-15.1-8.1-15.1l17.6-13.7h-9.5c-.1 1.3-2.6 3-2.6 3l-8.1 6.4s-3.5-6.6-4.1-7.9c-.3-.6-.3-1.4-.3-1.4H93.4c.8.6 1.2 1 1.6 1.7M70.3 34.8c-.5 1.8-2.1 1.8-2.1 1.8h-5.6c-2.4 0-1.9-2.3-1.9-2.3s.8-3.9 1.4-6c.5-2 2.1-1.8 2.1-1.8h8.2c-.1.1-1.4 5.6-2.1 8.3m17.5-14.9c1.1-5.3-3.5-8.6-6.2-8.6H53.7l-1.9 5.6c1.1-.6 2.6-.6 2.6-.6h18.1c.6 0 1.6.2 1.7 1.5 0 .3-.3 1.3-.4 1.8-.3 1.1-.8 1.7-1.8 1.7H56.4c-2.5 0-6.7 1.2-7.8 6-.3 1.2-.8 3.3-1.2 5.1-1.2 5 3 9.6 7.5 9.6h11c2.6 0 3.9-3.2 3.9-3.2.2 1.4.6 3.2.6 3.2H84c-1.2-1.9-.6-3.9-.6-3.9s3.1-12.2 4.4-18.2M35.4 9.6c-.7 2.6-1.3 5.1-1.3 5.1s-.4 2.4-2.3 2.4h-9.3L25 6.9h8.7c.5-.1 2.3.3 1.7 2.7m-4.2 16.2c-.4 1.9-1.3 5.7-1.5 6.5-.2.8-.7 2.8-3.4 2.8h-8.1L21 23.6h8.4c.3 0 2.1.3 1.8 2.2M42.7 0H10.8c.2.9.5 2.1.1 3.5-.1.3-8.4 33.6-8.9 35.1C1.6 40 0 42 0 42h36.9c4 0 5.8-3.6 6.1-4.7.3-1.1 1.5-5.5 2.4-9.5 1.2-5.5-3.6-7.5-3.6-7.5 4-.3 5.3-3.3 5.6-4.4.4-1.5 2-8.1 2-8.1.7-4.2-2.3-7.8-6.7-7.8"/></svg> </div> </div> </div> <div class="primary-bar"> <div class="primary-bar__content"> <a href="/" title="Home" rel="home" class="site-title"> Hospital Products </a> <div class="primary__container"> <nav aria-labelledby="block-bax-specialty-main-nav-menu-label" id="block-bax-specialty-main-nav" class="nav__primary" data-module="MegaNav"> <div class="visually-hidden" id="block-bax-specialty-main-nav-menu-label">Main Menu</div> <ul> <li> <a href="/baxter-supply-resources" role="button" tabindex="0" aria-haspopup="true" aria-controls="b55ff23c-25c7-4faf-9843-1096f2f880a9" aria-expanded="false" data-menu="b55ff23c-25c7-4faf-9843-1096f2f880a9" class="arrow-link down-arrow">Announcements & Resources </a> </li> <li> <a href="/alternate-sites" role="button" tabindex="0" aria-haspopup="true" aria-controls="8dd02fa0-e9e2-4b7d-b8d1-6922a4751902" aria-expanded="false" data-menu="8dd02fa0-e9e2-4b7d-b8d1-6922a4751902" class="arrow-link down-arrow">Alternate Sites of Care</a> </li> <li> <a href="" role="button" tabindex="0" aria-haspopup="true" aria-controls="2bdd421b-db7f-4add-8d68-a20244831e1d" aria-expanded="false" data-menu="2bdd421b-db7f-4add-8d68-a20244831e1d" class="arrow-link down-arrow">Acute Care Specialties</a> </li> <li> <a href="/our-products" role="button" tabindex="0" aria-haspopup="true" aria-controls="9b3802f5-60f1-417e-85d2-63e3a74f00a0" aria-expanded="false" data-menu="9b3802f5-60f1-417e-85d2-63e3a74f00a0" class="arrow-link down-arrow">Products</a> </li> <li> <a href="/education" role="button" tabindex="0" aria-haspopup="true" aria-controls="2fbc5961-43c5-46ae-b262-0967fb61c44c" aria-expanded="false" data-menu="2fbc5961-43c5-46ae-b262-0967fb61c44c" class="arrow-link down-arrow">Education</a> </li> <li> <a href="https://ecatalog.baxter.com/ecatalog/home.html" role="button" tabindex="0" aria-haspopup="true" aria-controls="e3b55d11-f043-4346-ac38-553c5b73515e" aria-expanded="false" data-menu="e3b55d11-f043-4346-ac38-553c5b73515e" class="arrow-link down-arrow">Product eCatalog</a> </li> </ul> </nav> <nav class="nav__product-search" data-module="SearchToggle"> <ul> <li> <button type="button" class="search"> <span class="visually-hidden">Search</span> <span class="icon-search icon"></span> </button> </li> </ul> </nav> </div> <button class="menu-toggle" aria-label="Menu" aria-expanded="false" aria-controls="mobileNav" aria-hidden="false"> <span class="menu-toggle-box"> <span class="menu-toggle-inner"></span> </span> </button> </div> </div> <div class="search-bar"> <div class="search-bar__inner wrapper--wide"> <form action="/search" method="get" id="global-search-form" accept-charset="UTF-8"> <label for="search_api_fulltext" class="visually-hidden">Search</label> <input id="search_api_fulltext" type="text" class="search-bar__input" name="search_api_fulltext" placeholder="Search..."> </form> </div> </div> <div id="mega-nav" class="mega-nav"> <div class="mega-nav--inner" id="navb55ff23c-25c7-4faf-9843-1096f2f880a9" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Announcements & Resources </h2> <p></p> <a href="/baxter-supply-resources" class="button arrow-link">Announcements & Resources </a> </div> <div class="links"> <ul> <li> <a href="/baxter-supply-resources" class="arrow-link"> Baxter Supply Resources </a> <p></p> </li> <li> <a href="https://www.baxter.com/baxter-newsroom/hurricane-helene-updates" class="arrow-link">Hurricane Supply Updates</a> <p></p> </li> <li> <a href="/baxter-non-dehp-product-resources" class="arrow-link"> Baxter non-DEHP Product Resources </a> <p></p> </li> </ul> </div> </div> </div> <div class="mega-nav--inner" id="nav8dd02fa0-e9e2-4b7d-b8d1-6922a4751902" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Alternate Sites of Care</h2> <p> Baxter is your trusted partner across the spectrum of health care. With a broad portfolio of products, we are there to support your needs in and out of the hospital setting. It’s all about care — everywhere care is given. </p> <a href="/alternate-sites" class="button arrow-link">Alternate Sites of Care</a> </div> <div class="links"> <ul> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/ambulatory-surgery-centers" class="arrow-link">Ambulatory Surgery Centers</a> <p> Helping surgery center clinicians safely deliver surgical care in an efficient, comfortable environment. Providing products that span admission through discharge. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/home-infusion" class="arrow-link">Home Infusion</a> <p> Offering flexibility and convenience for home infusion patients with products that help improve their quality of life, including parenteral nutrition, administration sets, IV solutions, IV pharmaceuticals and more. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/long-term-care-pharmacy" class="arrow-link">Long Term Care Pharmacy</a> <p> The needs of long-term care patients can be very broad and varied. Our extensive product portfolio can fill those needs with convenient, reliable options. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/oncology-infusion-clinics" class="arrow-link">Oncology & Infusion Clinics</a> <p> For comprehensive care at infusion clinics, we offer patient-centric solutions for infusion delivery, oncology injectable medications, parenteral IV solutions and more. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites#view-all" class="arrow-link">Emergency Medical Services</a> <p> Emergency situations call for reliable products that increase efficiency and reduce errors. We offer a broad pharmaceutical and IV solutions portfolio, so you have the right products at the right time. </p> </li> </ul> </div> </div> </div> <div class="mega-nav--inner" id="nav2bdd421b-db7f-4add-8d68-a20244831e1d" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Acute Care Specialties</h2> <p> Caring for hospitalized patients is complex. That’s why Baxter is focused on partnering with healthcare systems to enable clinicians to provide their best care to patients. </p> </div> <div class="links"> <ul> <li> <a href="/acute-care-specialties/infusion-systems-and-patient-monitoring" class="arrow-link"> Infusion Systems and Patient Monitoring </a> <p> Helping clinicians safely deliver medications and monitor patients at the bedside </p> </li> <li> <a href="/baxter-pharmacy-portfolio" class="arrow-link"> Pharmacy Portfolio The Power of Medicine </a> <p> Solutions for increased efficiency, improved tracking and advanced workflows in pharmacy operations to minimize waste and maximize patient safety </p> </li> <li> <a href="/acute-care-specialties/clinical-nutrition" class="arrow-link"> Clinical Nutrition </a> <p> Parenteral nutrition options to help address malnutrition in hospitals and healthcare systems and optimize the pharmacy’s workload </p> </li> </ul> </div> </div> </div> <div class="mega-nav--inner" id="nav2fbc5961-43c5-46ae-b262-0967fb61c44c" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Education</h2> <p></p> <a href="/education" class="button arrow-link">Education</a> </div> <div class="links"> <ul> <li> <a href="/education-resources/infusEd-infusion-education" class="arrow-link"> InfusEd: Infusion Education </a> <p> Medication delivery insights from HCPs for HCPs </p> </li> </ul> </div> </div> </div> </div> <div id="mega-nav" class="mega-nav"> <div class="mega-nav--inner" id="navb55ff23c-25c7-4faf-9843-1096f2f880a9" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Announcements & Resources </h2> <p></p> <a href="/baxter-supply-resources" class="button arrow-link">Announcements & Resources </a> </div> <div class="links"> <ul> <li> <a href="/baxter-supply-resources" class="arrow-link"> Baxter Supply Resources </a> <p></p> </li> <li> <a href="https://www.baxter.com/baxter-newsroom/hurricane-helene-updates" class="arrow-link">Hurricane Supply Updates</a> <p></p> </li> <li> <a href="/baxter-non-dehp-product-resources" class="arrow-link"> Baxter non-DEHP Product Resources </a> <p></p> </li> </ul> </div> </div> </div> <div class="mega-nav--inner" id="nav8dd02fa0-e9e2-4b7d-b8d1-6922a4751902" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Alternate Sites of Care</h2> <p> Baxter is your trusted partner across the spectrum of health care. With a broad portfolio of products, we are there to support your needs in and out of the hospital setting. It’s all about care — everywhere care is given. </p> <a href="/alternate-sites" class="button arrow-link">Alternate Sites of Care</a> </div> <div class="links"> <ul> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/ambulatory-surgery-centers" class="arrow-link">Ambulatory Surgery Centers</a> <p> Helping surgery center clinicians safely deliver surgical care in an efficient, comfortable environment. Providing products that span admission through discharge. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/home-infusion" class="arrow-link">Home Infusion</a> <p> Offering flexibility and convenience for home infusion patients with products that help improve their quality of life, including parenteral nutrition, administration sets, IV solutions, IV pharmaceuticals and more. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/long-term-care-pharmacy" class="arrow-link">Long Term Care Pharmacy</a> <p> The needs of long-term care patients can be very broad and varied. Our extensive product portfolio can fill those needs with convenient, reliable options. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites/oncology-infusion-clinics" class="arrow-link">Oncology & Infusion Clinics</a> <p> For comprehensive care at infusion clinics, we offer patient-centric solutions for infusion delivery, oncology injectable medications, parenteral IV solutions and more. </p> </li> <li> <a href="https://ushospitalproducts.baxter.com/alternate-sites#view-all" class="arrow-link">Emergency Medical Services</a> <p> Emergency situations call for reliable products that increase efficiency and reduce errors. We offer a broad pharmaceutical and IV solutions portfolio, so you have the right products at the right time. </p> </li> </ul> </div> </div> </div> <div class="mega-nav--inner" id="nav2bdd421b-db7f-4add-8d68-a20244831e1d" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Acute Care Specialties</h2> <p> Caring for hospitalized patients is complex. That’s why Baxter is focused on partnering with healthcare systems to enable clinicians to provide their best care to patients. </p> </div> <div class="links"> <ul> <li> <a href="/acute-care-specialties/infusion-systems-and-patient-monitoring" class="arrow-link"> Infusion Systems and Patient Monitoring </a> <p> Helping clinicians safely deliver medications and monitor patients at the bedside </p> </li> <li> <a href="/baxter-pharmacy-portfolio" class="arrow-link"> Pharmacy Portfolio The Power of Medicine </a> <p> Solutions for increased efficiency, improved tracking and advanced workflows in pharmacy operations to minimize waste and maximize patient safety </p> </li> <li> <a href="/acute-care-specialties/clinical-nutrition" class="arrow-link"> Clinical Nutrition </a> <p> Parenteral nutrition options to help address malnutrition in hospitals and healthcare systems and optimize the pharmacy’s workload </p> </li> </ul> </div> </div> </div> <div class="mega-nav--inner" id="nav2fbc5961-43c5-46ae-b262-0967fb61c44c" > <div class="wrapper--wide"> <div class="feature"> <h2 class="mega-nav__heading">Education</h2> <p></p> <a href="/education" class="button arrow-link">Education</a> </div> <div class="links"> <ul> <li> <a href="/education-resources/infusEd-infusion-education" class="arrow-link"> InfusEd: Infusion Education </a> <p> Medication delivery insights from HCPs for HCPs </p> </li> </ul> </div> </div> </div> </div> <div class="mobile-nav" data-module="MobileNav" id="mobileNav"> <div class="mobile-nav__content"> <ul class="mobile-nav__items"> <li class="mobile-nav__item"> <a href="/baxter-supply-resources" data-drupal-link-system-path="node/566">Announcements & Resources </a> </li> <li class="mobile-nav__item"> <a href="/alternate-sites" data-drupal-link-system-path="node/761">Alternate Sites of Care</a> </li> <li class="mobile-nav__item has-children"> <a data-sub-menu="true" href="#" class="">Acute Care Specialties</a> <span class="subnav__toggle arrow-link right-arrow"></span> <div class="mobile-nav__submenu-wrapper"> <a href="#" class="mobile-nav__back">Back</a> <ul class="mobile-nav__submenu"> <li class="mobile-nav__sublink-active"> <a href="">Acute Care Specialties</a> </li> <li class="mobile-nav__sublink"> <a href="/acute-care-specialties/infusion-systems-and-patient-monitoring" data-drupal-link-system-path="node/416">Infusion Systems and Patient Monitoring</a> </li> <li class="mobile-nav__sublink"> <a href="/acute-care-specialties/clinical-nutrition" data-drupal-link-system-path="node/276">Clinical Nutrition</a> </li> <li class="mobile-nav__sublink"> <a href="/baxter-pharmacy-portfolio" data-drupal-link-system-path="node/406">Pharmacy Portfolio The Power of Medicine</a> </li> </ul> </div> </li> <li class="mobile-nav__item"> <a href="/our-products" target="" rel="" data-drupal-link-system-path="node/431">Products</a> </li> <li class="mobile-nav__item"> <a href="/education" data-drupal-link-system-path="node/456">Education</a> </li> <li class="mobile-nav__item"> <a href="https://ecatalog.baxter.com/ecatalog/home.html" target="_blank">Product eCatalog</a> </li> </ul> <div class="search-bar"> <div class="search-bar__inner wrapper--wide"> <form action="/search" method="get" accept-charset="UTF-8"> <label for="search_api_fulltext_mobile" class="visually-hidden">Search</label> <input type="text" class="search-bar__input" id="search_api_fulltext_mobile" name="search_api_fulltext" placeholder="Search..."> <button type="button" class="search"> <span class="visually-hidden">Search</span> <span class="icon-search icon"></span> </button> </form> </div> </div> <div class="nav-top-bar"> <div class="nav-top-bar__content"> <a class="nav-top-bar__ext-link arrow-link" href="https://www.baxter.com">Explore baxter.com <span class="icon icon-external-link"></span></a> <div class="nav-top-bar__text"> <p class="disclaimer">This site is intended for US healthcare professionals</p> <a href="#isi" class="isi-link">Important Safety Information</a> </div> </div> </div> </div> </div> </header> <main id="main-content" class="main"> <header class="hero hero--has-image hero--brand-darkest hero--large hero--has-foreground-image" style="background-image: url(/sites/g/files/ebysai2186/files/styles/long_image/public/2023-04/Zosyn_LandingPage_Rv8_NewHeader.png?itok=ES3l6ejk)"> <div class="hero-content"> <div class="wrapper--wide"> <div class="hero-text"> <h1 class="hero-heading"> A Homecoming — ZOSYN (piperacillin and tazobactam) Injection </h1> <div class="hero-subheading"> One source. One contact. </div> </div> </div> </div> </header> <div class="wrapper--wide"> <div> <div data-drupal-messages-fallback class="hidden"></div> </div> <div> <div id="block-bax-specialty-content"> <p class="disclaimer"></p> <section class="text-area wrapper" > <div class="text-area__inner"> <h2 class="section-title__title"> Indications and Select Important Risk Information: </h2> <div class="text-area__wysiwyg"> <p><strong>Zosyn</strong> is a combination of piperacillin, a penicillin-class antibacterial and tazobactam, a beta-lactamase inhibitor, indicated for the treatment of:<br> Intra-abdominal infections in adult and pediatric patients 2 months of age and older, Nosocomial pneumonia in adult and pediatric patients 2 months of age and older, Skin and skin structure infections in adults, Female pelvic infections in adults, and Community-acquired pneumonia in adults.</p> <p><strong>Contraindications</strong></p> <p><strong>Zosyn </strong>is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or beta-lactamase inhibitors.</p> <p><strong>Warnings and Precautions</strong></p> <p><strong>Hypersensitivity Adverse Reactions: </strong>Serious and occasionally fatal hypersensitivity (anaphylactic/anaphylactoid) reactions (including shock) have been reported in patients receiving therapy with <strong>Zosyn</strong>. These reactions are more likely to occur in individuals with a history of penicillin, cephalosporin, or carbapenem hypersensitivity or a history of sensitivity to multiple allergens. If an allergic reaction occurs, <strong>Zosyn</strong> should be discontinued and appropriate therapy instituted.<br> <br> <a href="#isi">Please read the accompanying full Indications and Important Risk Information</a> and <a href="https://baxterpi.com/pi-pdf/Zosyn%20PI%20April%202023-071904795.pdf">full Prescribing Information</a></p> </div> </div> </section> <section class="text-area wrapper" > <div class="text-area__inner"> <h2 class="section-title__title"> One source. One contact. </h2> <div class="text-area__wysiwyg"> <p>The first and only premix piperacillin and tazobactam injection manufactured by and available from Baxter with one point of contact.</p> </div> </div> </section> <section class="text-area wrapper" > <div class="text-area__inner"> <h2 class="section-title__title"> Baxter is the leader in frozen premix IV anti-infectives </h2> <div class="text-area__wysiwyg"> <p>Baxter offers practical and innovative products in premix ready-to-use IV formulations, including frozen, which<br> may increase hospital efficiency while helping to support patient care.</p> <p>How might your institution benefit from adding Baxter premixes? Choose <strong>Zosyn</strong> premix for patient safety and<br> operational efficiency.</p> </div> </div> </section> <section class="card-container card--half" > <div class="wrapper"> <div class="card card--hybrid"> <div class="card__inner"> <span class="icon icon-safety"></span> <h3> Safety </h3> <p>• Standardized concentration may help reduce medication errors associated with compounding preparations<sup>1,2</sup></p> <p>• Barcoded for bedside scanning to help ensure the right patient gets the right medication<sup>1</sup></p> <p> </p> </div> </div> <div class="card card--hybrid"> <div class="card__inner"> <span class="icon icon-heritage"></span> <h3> Efficiency </h3> <p>• No admixing or batching required—which may help streamline deployment and save pharmacy time and resources</p> <p>• Premix medications like <strong>Zosyn</strong> premix support inventory management and help reduce waste<sup>3</sup></p> </div> </div> <div class="card card--hybrid"> <div class="card__inner"> <span class="icon icon-nutritional"></span> <h3> Consistent concentration </h3> <p>• A manufacturer-prepared piperacillin and tazobactam injection helps ensure that patients receive a consistent concentration of medication</p> </div> </div> <div class="card card--hybrid"> <div class="card__inner"> <span class="icon icon-giving"></span> <h3> Value </h3> <p>• Manufacturer-prepared premix medications have a shelf life of 9 to 24 months</p> </div> </div> <div class="card card--hybrid"> <div class="card__inner"> <span class="icon icon-patient-bed"></span> <h3> Patient care </h3> <p>• Potentially shortening the time between ordering and administration may allow you to spend more time with your patients</p> </div> </div> </div> </section> <section class="text-area wrapper" > <div class="text-area__inner"> <h2 class="section-title__title"> Standardized and Consistent </h2> <div class="text-area__wysiwyg"> <p><strong>Zosyn</strong> premix is available in 3 strengths to support your institution’s needs.</p> </div> </div> </section> <section class="slideshow"> <div><div data-module="Carousel" > <section class="slideshow"> <div><div data-module="Carousel" > <figure class="figure--full-width"> <img loading="lazy" src="/sites/g/files/ebysai2186/files/styles/long_image/public/2023-03/Zosyn_ProductinfoTableUpdate_0.png?itok=v0z5o4VC" width="1320" height="700" alt="Standardized and Consistent: Zosyn premix is available in 3 strengths to support your institution’s needs" /> <figcaption class="wrapper"> <p class="disclaimer"></p> </figcaption> </figure> </div></div> </section> </div></div> </section> <section class="card-container card--half" > <div class="wrapper"> <div class="card card--hybrid"> <div class="card__inner card__inner--hover"> <div class="media media--type-image media--view-mode-"> <img loading="lazy" src="/sites/g/files/ebysai2186/files/styles/small_tile_image/public/2023-03/ZosynReadytoAdd.png?itok=m007voAl" width="600" height="260" alt="add ZOSYN premix or other Frozen Premix Medications to your institution?" /> </div> <h3> Contact your representative directly or: Order via eCommerce Solutions </h3> <ul class="card--links"> <li class="card-link"> <a href="https://ecatalog.baxter.com/ecatalog/loadproductsearchresults.html?cid=20016&lid=10001&hid=null&searchCriteriaPattern=zosyn" class="arrow-link"> Click here</a> </li> </ul> </div> </div> <div class="card card--hybrid"> <div class="card__inner card__inner--hover"> <div class="media media--type-image media--view-mode-"> <img loading="lazy" src="/sites/g/files/ebysai2186/files/styles/small_tile_image/public/2023-03/ZosynCalloutWebsite_SellSheet.png?itok=vVtBS947" width="600" height="260" alt="The ZOSYN Sells Sheet has everything you need to add the frozen premix to your institution." /> </div> <h3> Download the ZOSYN Premix Sell Sheet </h3> <ul class="card--links"> <li class="card-link"> <a href="https://ushospitalproducts.baxter.com/sites/g/files/ebysai2186/files/2023-03/Zosyn%20SellSheet_Rv12.2_Interactive.pdf" class="arrow-link"> Click here</a> </li> </ul> </div> </div> </div> </section> <section class="text-area wrapper" > <div class="text-area__inner"> <h2 class="section-title__title"> Other ways to order ZOSYN premix: </h2> <div class="text-area__wysiwyg"> <p>Visit: <a href="https://ecatalog.baxter.com/ecatalog/loadproductsearchresults.html?cid=20016&lid=10001&hid=null&searchCriteriaPattern=zosyn">Product eCatalog</a><br> Phone: <a href="tel:1-888-229-0001">1-888-229-0001</a><br> Government Customer Service Number: <a href="tel:1-800-777-2298">1-800-777-2298</a></p> </div> </div> </section> <section class="text-area wrapper" > <div class="text-area__inner"> <h2 class="section-title__title"> Add ZOSYN premix or other frozen premix medications for your facility </h2> <div class="text-area__wysiwyg"> <p>Please ask your Baxter sales representative how <strong>Zosyn</strong> premix can help your healthcare operations.<br> Don’t have one? Call: <a href="tel:1-888-229-0001">1-888-229-0001</a><br> Or visit: <a href="https://ecatalog.baxter.com/ecatalog/loadproductsearchresults.html?cid=20016&lid=10001&hid=null&searchCriteriaPattern=zosyn">Product eCatalog</a></p> </div> </div> </section> <section class="footer-cta lazyload footer-cta__bright" data-bg="/sites/g/files/ebysai2186/files/styles/long_image/public/2021-09/RTU-Footer.jpg?itok=4z4axVht"> <div class="footer-cta--container wrapper"> <div class="footer-cta--text"> <h3 class="footer-cta__heading"></h3> <p class="footer-cta__description"> For additional product information please visit our online catalog or contact your Baxter sales representative. If you do not have a sales representative please contact customer service at 1-888-229-0001. </p> </div> <div class="footer-cta--links"> <a href="https://ecatalog.baxter.com/ecatalog/home.html" class="button arrow-link"> U.S. Product Catalog </a> <a href="https://www.baxter.com/contact-us" class="button arrow-link"> Contact Us </a> </div> </div> </section> <section class="isi" id="isi"> <div class="wrapper"> <h4></h4> <h2>ZOSYN (piperacillin and tazobactam) Injection</h2> <h3>Indications and Important Risk Information</h3> <h3>Indications</h3> <p><strong>Zosyn</strong> is a combination of piperacillin, a penicillin-class antibacterial and tazobactam, a beta-lactamase inhibitor, indicated for the treatment of:</p> <p>• Intra-abdominal infections in adult and pediatric patients 2 months of age and older</p> <p>• Nosocomial pneumonia in adult and pediatric patients 2 months of age and older</p> <p>• Skin and skin structure infections in adults</p> <p>• Female pelvic infections in adults</p> <p>• Community-acquired pneumonia in adults</p> <p>To reduce the development of drug-resistant bacteria and maintain the effectiveness of <strong>Zosyn</strong> and other antibacterial drugs, <strong>Zosyn</strong> should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.</p> <h3>Important Risk Information</h3> <h3>Contraindications</h3> <p><strong>Zosyn</strong> is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or beta-lactamase inhibitors.</p> <h3>Warnings and Precautions</h3> <p>• <strong>Hypersensitivity Adverse Reactions</strong>: Serious and occasionally fatal hypersensitivity (anaphylactic/anaphylactoid) reactions (including shock) have been reported in patients receiving therapy with <strong>Zosyn</strong>. These reactions are more likely to occur in individuals with a history of penicillin, cephalosporin, or carbapenem hypersensitivity or a history of sensitivity to multiple allergens. If an allergic reaction occurs, <strong>Zosyn</strong> should be discontinued and appropriate therapy instituted.</p> <p>• <strong>Severe Cutaneous Adverse Reactions</strong>: <strong>Zosyn</strong> may cause severe cutaneous adverse reactions, such as Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalized exanthematous pustulosis. If patients develop a skin rash they should be monitored closely and <strong>Zosyn</strong> discontinued if lesions progress.</p> <p>• <strong>Hemophagocytic Lymphohistiocytosis (HLH)</strong>: Cases of HLH have been reported in pediatric and adult patients treated with <strong>Zosyn</strong>. Signs and symptoms of HLH may include fever, rash, lymphadenopathy, hepatosplenomegaly and cytopenia. If HLH is suspected, discontinue <strong>Zosyn</strong> immediately and institute appropriate management.</p> <p>• <strong>Hematologic Adverse Reactions</strong>: Bleeding manifestations have occurred in some patients receiving beta-lactam drugs, including piperacillin. These reactions have sometimes been associated with abnormalities of coagulation tests such as clotting time, platelet aggregation and prothrombin time, and are more likely to occur in patients with renal failure. If bleeding manifestations occur, <strong>Zosyn</strong> should be discontinued and appropriate therapy instituted. The leukopenia/neutropenia associated with <strong>Zosyn</strong> administration appears to be reversible and most frequently associated with prolonged administration.<br> Periodic assessment of hematopoietic function should be performed, especially with prolonged therapy, i.e., ≥ 21 days.</p> <p>• <strong>Central Nervous System Adverse Reactions</strong>: As with other penicillins, <strong>Zosyn</strong> may cause neuromuscular excitability or seizures. Patients receiving higher doses, especially patients with renal impairment may be at greater risk for central nervous system adverse reactions. Closely monitor patients with renal impairment or seizure disorders for signs and symptoms of neuromuscular excitability or seizures.</p> <p>• <strong>Nephrotoxicity in Critically Ill Patients</strong>: The use of <strong>Zosyn</strong> was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in critically ill patients. Alternative treatment options should be considered in the critically ill population. If alternative treatment options are inadequate or unavailable, monitor renal function during treatment with <strong>Zosyn</strong>.</p> <p>• <strong><em>Clostridioides difficile</em>-associated diarrhea (CDAD)</strong>: CDAD has been reported with use of nearly all antibacterial agents, including <strong>Zosyn</strong>, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of <em>C. difficile</em>.<br> <em>C. difficile</em> produces toxins A and B which contribute to the development of CDAD. Hypertoxin producing strains of <em>C. difficile</em> cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibacterial drug use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.<br> If CDAD is suspected or confirmed, ongoing antibacterial drug use not directed against <em>C. difficile</em> may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of <em>C. difficile</em>, and surgical evaluation should be instituted as clinically indicated.</p> <p>• <strong>Adverse Reactions</strong>: The most common adverse reactions (incidence >5%) are diarrhea, constipation, nausea, headache, and insomnia.</p> <p>• <strong>Renal Impairment</strong>: In patients with creatinine clearance ≤ 40 mL/min and dialysis patients (hemodialysis and CAPD), the intravenous dose of <strong>Zosyn</strong> should be reduced to the degree of renal function impairment.</p> <p>• <strong>Drug Interactions</strong>:</p> <ul> <li><strong>Zosyn</strong> administration can significantly reduce tobramycin concentrations in hemodialysis patients. Monitor tobramycin concentrations in these patients.</li> <li>Probenecid prolongs the half-lives of piperacillin and tazobactam and should not be co-administered with <strong>Zosyn</strong> unless the benefit outweighs the risk.</li> <li>Co-administration of <strong>Zosyn</strong> with vancomycin may increase the incidence of acute kidney injury. Monitor kidney function in patients receiving <strong>Zosyn</strong> and vancomycin.</li> <li>Monitor coagulation parameters in patients receiving <strong>Zosyn</strong> and heparin or oral anticoagulants.</li> <li><strong>Zosyn</strong> may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. Monitor for adverse reactions related to neuromuscular blockade.</li> </ul> <p>Please see accompanying <a href="https://baxterpi.com/pi-pdf/Zosyn%20PI%20April%202023-071904795.pdf">full Prescribing Information</a> for <strong>Zosyn</strong>.</p> </div> </section> <section class="references"> <div class="accordion__container"> <div class="wrapper"> <div class="accordion" data-module="Accordion"> <button id="toggle-reference01" class="accordion__toggle" aria-expanded="false" aria-controls="reference01"> References: <span class="icon icon-arrow-down"></span></button> <div id="reference01" class="accordion__content" aria-hidden="true" aria-labelledby="toggle-reference01"> <ol class="footnotes"> <li><p>Institute for Safe Medication Practices. ISMP Guidelines for Sterile Compounding and the Safe Use of Sterile Compounding Technology; 2022. https://www.ismp.org/resources/guidelines-sterile-compounding-and-safe-use-sterile-compounding-technology. Accessed July 8, 2022.</p></li> <li><p>Billstein-Leber M, Carrillo CJD, Cassano AT, Moline K, Robertson JJ. ASHP Guidelines on Preventing Medication Errors in Hospitals. <em>Am J Health-Syst Pharm</em>. 2018 Oct;75(19):1493-1517. doi 10.2146/ajhp170811.</p></li> <li><p>ASHP Expert Panel on Medication Cost Management. ASHP guidelines on medication cost management strategies for hospitals and health systems. <em>Am J Health-Syst Pharm</em>. 2008;65(14):1368-1384.</p></li> </ol> </div> </div> </div> </div> </section> </div> </div> </div> </main> <div> <footer class="footer"> <div class="wrapper"> <div class="row footer--menu"> </div> <div class="row footer--menu"> <div class="footer__about"> <h2 class="footer__links-heading"> About Us </h2> <p>Every day, millions of patients and caregivers rely on Baxter’s leading portfolio of critical, nutritional, renal, hospital and surgical care products and services. For more than 90 years, we’ve been operating at the critical intersection where innovations that save and sustain lives meet the healthcare providers that make it happen.</p> </div> </div> <div class="row footer--social-selector"> <div class="footer__links"> <ul class="social-follow"> </ul> </div> </div> <div class="row footer--bottom"> <ul class="footer__utility"> <li> <a href="/privacy-policy">Privacy Policy</a></li> <li> <a href="/california-privacy">California Privacy </a></li> <li> <a href="/hipaa-notice-privacy-practices">HIPAA Notice of Privacy Practices</a></li> <li> <a href="/terms-use">Terms of Use</a></li> <li> <a href="/cookies">Cookies</a></li> </ul> <div class="footer__copyright"> <p>©Copyright 2024 Baxter. All rights reserved.</p> <p> US-PH54-220026 v3.0 5/2023 </p> </div> </div> </div> </footer> <!-- Global script includes --> </div> <div style="display: none;"> <div> <div id="site-exit-prompt" class="modal " role="dialog" aria-labelledby="label-site-exit-prompt" data-module="SiteExitPrompt" style="display: none"> <div class="modal__content"> <h2 id="label-site-exit-prompt"> Do you want to leave our website? </h2> <div class="modal__message"> <p>By continuing, you will leave our website and go to a third-party site. We are not responsible for any content on the third-party site.</p> </div> <a href="#" class="button button--solid arrow-link" id=site-exit-stay> Stay on this site. </a> <a href="#" class="button button--solid arrow-link" id=site-exit-leave> Take me to the new site </a> </div> </div> </div> </div> </div> <script>window.dataLayer = window.dataLayer || []; window.dataLayer.push({"drupalLanguage":"en","drupalCountry":"","siteName":"Hospital Care","entityCreated":"1678714648","entityLangcode":"en","entityStatus":"1","entityUid":"174166","entityUuid":"c44d4722-2be6-41c8-9225-6949f7a14abb","entityVid":"52421","entityName":"bstorms","entityType":"node","entityBundle":"specialty_product_detail","entityId":"991","entityTitle":"A Homecoming — ZOSYN (piperacillin and tazobactam) Injection","userUid":0});</script> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/991","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"dataLayer":{"defaultLang":"en","languages":{"en":{"id":"en","name":"English","direction":"ltr","weight":0}}},"oktaGateControl":{"baseUrl":""},"siteExitModal":{"whitelist":["*.baxter.com","*.baxterglobal.com","players.brightcove.net","*.ecatalog.baxter.com","*.baxterpi.com",".baxterpi.com","baxterpi.com","baxterpi.com\/pi-pdf\/","baxter-usmpprd.irmscare.com","measuredontestimate.com","*hillrom.com","hillrom.com","*hill-rom.com","hill-rom.com","*.hillrom.com","*baxterhealthcare.csod.com","baxterhealthcare.csod.com","spectrumiq.com"]},"statistics":{"data":{"nid":"991"},"url":"\/core\/modules\/statistics\/statistics.php"},"ajaxTrustedUrl":{"\/search":true},"user":{"uid":0,"permissionsHash":"237046da9918f09208fb3cfb73df0b2d3732ae48f7537c9c999c5b592d29fd3d"}}</script> <script src="/sites/g/files/ebysai2186/files/js/js_NpJFMBTwl6djguttRsIevkJzFnoR1OhGwGNJUHnJlqc.js?scope=footer&delta=0&language=en&theme=bax_specialty_theme&include=eJxtzlEKwjAQBNALtc2RwqRZk-i2G7IbMbcXBS1U_4Z5MEyEgTGouUAZ9yJNJ7kZfIKRX2W3JuxYknSbdKjR5gKUpoCHfwVvmTZyV50vIkbtDIklgGe1wWVPP2rbHD8X3qiV1gK28Xf4rKd1NVhRK6u62HoFL0czVTSkhpq_eDRL32sPXDRTfAIqU2xC"></script> </body> </html>