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class="ecl-breadcrumb__segment ecl-breadcrumb__current-page" data-ecl-breadcrumb-item="static" aria-current="page">Animals in science</li></ol></nav><div class="ecl-page-header__info"><h1 class="ecl-page-header__title"><span>Animals in science</span></h1></div><div class="ecl-page-header__description-container"><p class="ecl-page-header__description">EU actions for the protection of animals used for scientific purposes </p></div></div></div> </div> <main class="ecl-u-pb-xl" id="main-content" data-inpage-navigation-source-area="h2.ecl-u-type-heading-2, div.ecl-featured-item__heading"> <div class="ecl-container"> <div class="ecl-row"> <div class="ecl-col-s-12 ewcms-top-sidebar"> <div> <div data-drupal-messages-fallback class="hidden"></div> </div> </div> </div> <div class="ecl-row"> <div class="ecl-col-s-12"> <div id="block-ewcms-theme-main-page-content" data-inpage-navigation-source-area="h2, div.ecl-featured-item__heading" class="ecl-u-mb-l"> <article dir="ltr"> <div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5342"></a> <div class="ecl-row inpage-navigation-container"> <div class="ecl-col-l-3"> <nav class="ecl-inpage-navigation oe-theme-ecl-inpage-navigation ecl-u-z-dropdown" data-ecl-auto-init="InpageNavigation" data-ecl-auto-initialized="true" data-ecl-inpage-navigation="true" aria-labelledby="ecl-inpage-navigation-1011203803" ><div class="ecl-inpage-navigation__title" id="ecl-inpage-navigation-1011203803">Page contents</div><div class="ecl-inpage-navigation__body"><div class="ecl-inpage-navigation__trigger-wrapper"><button type="button" class="ecl-inpage-navigation__trigger" id="ecl-inpage-navigation-1011203803-trigger" data-ecl-inpage-navigation-trigger="true" aria-controls="ecl-inpage-navigation-list" aria-expanded="false"><span class="ecl-inpage-navigation__trigger-current" data-ecl-inpage-navigation-trigger-current="true">Page contents</span><svg class="ecl-icon ecl-icon--xs ecl-icon--rotate-180 ecl-inpage-navigation__trigger-icon" focusable="false" aria-hidden="false" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#corner-arrow"></use></svg></button></div><ul class="ecl-inpage-navigation__list" data-ecl-inpage-navigation-list="true" id="ecl-inpage-navigation-1011203803-list"></ul></div></nav> </div> <div class="ecl-col-l-9" data-inpage-navigation-source-area="h2, div.ecl-featured-item__heading"> <div class="ecl-u-mb-2xl"> <a id="paragraph_5321"></a> <div> <div class="ecl"> <h2 class="ecl-u-type-heading-2">Overview </h2> </div> <div class="ecl"><p>The protection and welfare of animals is a priority for the EU. This includes wildlife, zoo animals, farm animals, animals in transport and animals used for scientific purposes. Regarding animals in science, EU legislation is unique as it sets a final goal of full replacement of all animals used for scientific and educational purposes and is taking concrete action towards that goal.</p> <p>Studies that still need to be carried out on animals must be done in compliance with specific regulations that aim to improve the welfare of those animals. This includes studies on increasing the basic understanding of human or animal biology, developing or producing new medicines, physiological studies, environmental effects or testing chemicals or new food additives.</p></div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5322"></a> <div> <div class="ecl"> <h2 class="ecl-u-type-heading-2">Objectives </h2> </div> <div class="ecl"><p>The EU aims to</p> <ul> <li>harmonise legislation to promote EU competitiveness and innovation </li> <li>improve animal welfare and establish the “Three Rs principle” (replacement, reduction and refinement) in all use and care practices when animals still needed in research and testing</li> <li>improve transparency</li> </ul></div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5323"></a> <div> <div class="ecl"> <h2 class="ecl-u-type-heading-2">Law </h2> </div> <div class="ecl"><p>The first Directive for the protection of animals in science was adopted in 1986 and was replaced by <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32010L0063">Directive 2010/63/EU</a>. <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=uriserv:OJ.L_.2019.170.01.0115.01.ENG&toc=OJ:L:2019:170:TOC">Regulation (EU)2019/1010</a> introduced a new level of transparency to help progress towards eventually replacing animal use in science. The amendments have been incorporated in <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A02010L0063-20190626">the consolidated text of the Directive</a>.</p></div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5648"></a> <div> <div class="ecl"> <h2 class="ecl-u-type-heading-2">The “Three Rs”</h2> </div> <div class="ecl"><p>EU legislation on animals in science centers on the principle of the “Three Rs”: replacement, reduction and refinement, which <a href="https://caat.jhsph.edu/principles/the-principles-of-humane-experimental-technique" class="ecl-link ecl-link--icon ecl-link--icon-after"><span class="ecl-link__label">first appeared in 1959</span><svg class="ecl-icon ecl-icon--xs ecl-link__icon" focusable="false" aria-hidden="true" xmlns:xlink="http://www.w3.org/1999/xlink"><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#external" /></svg></a>.</p> <p>Replacement can be defined as methods, strategies or approaches that do not involve the use of live animals. Reduction covers any approach that will result in fewer animals being used to achieve the same objective. Refinement signifies the modification of any procedures or practices from the time the experimental animal is born until its death to minimise its suffering and enhance its well-being, or by moving from species that are considered more sentient to those less sentient.</p> <p>The EU undertakes several activities towards these shared goals, including</p> <ul> <li><strong>funding</strong> for research</li> <li>hosting the <strong>E</strong><strong>U Reference Laboratory for Alternatives to Animal Testing</strong> (EURL ECVAM)</li> <li><strong>international harmonisation</strong> of regulatory testing requirements</li> <li>and a <strong>public-private partnership</strong> to advance alternatives in the area of regulatory use - the European Partnership for Alternative Approaches to Animal Testing (EPAA)</li> </ul> <h4>EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM)</h4> <p>The Joint Research Centre’s EU Reference Laboratory for Alternatives to Animal Testing (<a href="https://joint-research-centre.ec.europa.eu/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam_en">EURL ECVAM</a>), established by Directive 2010/63/EU, works on the development and promotion of non-animal approaches to testing and research. Among its tasks is to validate methods which replace, reduce or refine the use of animals for the safety and efficacy/potency testing of chemicals, biologicals and vaccines.</p> <p>The <a href="https://data.jrc.ec.europa.eu/dataset/jrc-eurl-ecvam-eurl-ecvam-3rs">Inventory of 3Rs knowledge sources</a> is a result of an assessment of technologies, information sources and networks from all relevant sectors with potential impact on the advancement of the “Three Rs” carried out by EURL ECVAM. EURL ECVAM also works to advance non-animal models used in <a href="https://joint-research-centre.ec.europa.eu/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam/biomedical-research_en">biomedical research</a>. EURL ECVAM has published a series of studies to review available and emerging non-animal models being used for research in various disease areas with the aim to identify and describe specific research contexts where animal models have been put aside in favour of novel non-animal techniques.</p> <h4>International harmonisation</h4> <p>A regulatory acceptance of alternative methods is required internationally if true reduction in animal use is to be delivered. To that end, the Commission is actively promoting alternative approaches on international fora such as <a href="https://www.oecd.org/chemicalsafety/testing/" class="ecl-link ecl-link--icon ecl-link--icon-after"><span class="ecl-link__label">OECD</span><svg class="ecl-icon ecl-icon--xs ecl-link__icon" focusable="false" aria-hidden="true" xmlns:xlink="http://www.w3.org/1999/xlink"><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#external" /></svg></a>, <a href="https://www.ich.org/" class="ecl-link ecl-link--icon ecl-link--icon-after"><span class="ecl-link__label">ICH</span><svg class="ecl-icon ecl-icon--xs ecl-link__icon" focusable="false" aria-hidden="true" xmlns:xlink="http://www.w3.org/1999/xlink"><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#external" /></svg></a> and <a href="https://www.vichsec.org/" class="ecl-link ecl-link--icon ecl-link--icon-after"><span class="ecl-link__label">VICH</span><svg class="ecl-icon ecl-icon--xs ecl-link__icon" focusable="false" aria-hidden="true" xmlns:xlink="http://www.w3.org/1999/xlink"><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#external" /></svg></a>, as well as during bilateral discussions with third countries.</p> <p>Moreover, the International Cooperation on Alternative Test Methods (<a href="https://joint-research-centre.ec.europa.eu/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam/alternative-methods-toxicity-testing/advisory-and-consultation-bodies/international-cooperation-alternative-test-methods-icatm_en">ICATM</a>) includes governmental organisations from the EU, the US, Japan, Canada, South Korea, Brazil and China. It aims at promoting enhanced international cooperation and coordination on the scientific development, validation and regulatory use of alternative approaches.</p> <h4>European Partnership for Alternative Approaches to Animal Testing (<a href="https://single-market-economy.ec.europa.eu/sectors/chemicals/european-partnership-alternative-approaches-animal-testing_en" class="ecl-link">EPAA</a>)</h4> <p>The Partnership is a voluntary collaboration between the European Commission, European trade associations, and companies from seven industry sectors. The partners are committed to pooling knowledge and resources to accelerate the development, validation and acceptance of alternative approaches to further the "Three Rs" in regulatory testing.</p> <h4>Further information</h4> <ul> <li>Archive of reference material on <a href="https://wayback.archive-it.org/org-1495/20230304151840/https://ec.europa.eu/environment/chemicals/lab_animals/3r/acceptance_en.htm" class="ecl-link">formal validation, regulatory acceptance and use of alternatives</a></li> <li><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/493c45e6-dfa4-4eb9-a62e-60a71cddfa24/details?download=true" class="ecl-link">Working Document on the Availability of Information on the Three Rs</a></li> <li>Some Member States provide voluntary reports on their progress and practical measures taken related to the Three Rs. View these <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/54502099-05bd-4210-b6f9-d99db6e178b1" class="ecl-link">progress reports here</a>.</li> <li><a href="https://journals.sagepub.com/doi/full/10.1177/02611929221099165" class="ecl-link ecl-link--icon ecl-link--icon-after"><span class="ecl-link__label">“Three R” centres</span><svg class="ecl-icon ecl-icon--xs ecl-link__icon" focusable="false" aria-hidden="true" xmlns:xlink="http://www.w3.org/1999/xlink"><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#external" /></svg></a> across Europe</li> </ul></div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5653"></a> <div class="ecl-content-item-block"><div class="ecl-row"><div class="ecl-content-item-block__title ecl-col-12"><h2 class='ecl-u-type-heading-2'>EU networks</h2></div></div><div class="ecl-row"><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 "><article class="ecl-navigation-list__item ecl-navigation-list__item--no-border" ><div class="ecl-content-block ecl-navigation-list__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://joint-research-centre.ec.europa.eu/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam/alternative-methods-toxicity-testing/eu-netval-european-union-network-laboratories-validation-alternative-methods_en" class="ecl-link ecl-link--standalone" >European Union Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL)</a></div><div class="ecl-content-block__description"><div class="ecl"><p>The Network provides support for EURL ECVAM validation studies aimed at assessing the reliability and relevance of alternative methods that have a potential to replace, reduce or refine the use of animals for scientific purposes.</p></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 "><article class="ecl-navigation-list__item ecl-navigation-list__item--no-border" ><div class="ecl-content-block ecl-navigation-list__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://joint-research-centre.ec.europa.eu/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam/alternative-methods-toxicity-testing/advisory-and-consultation-bodies/parere-eurl-ecvam-network-preliminary-assessment-regulatory-relevance_en" class="ecl-link ecl-link--standalone" >PARERE network</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Various relevant EU regulatory agencies, including EFSA, ECHA and EMA , together with the Member States, constitute the Preliminary Assessment of Regulatory Relevance network, known as PARERE. EURL ECVAM systematically consults the Network on the proposed alternative approaches and strategies.</p></div></div><div class="ecl-content-block__link-container"><ul class="ecl-content-block__link-list"><li class="ecl-content-block__link-item"><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/ad6fc22a-bb6b-4be7-b8dc-e25da5f2fd19/details?download=true" class="ecl-link ecl-link--standalone" >Contact details for the PARERE members</a></li></ul></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 last-item-column"><article class="ecl-navigation-list__item ecl-navigation-list__item--no-border" ><div class="ecl-content-block ecl-navigation-list__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://ec.europa.eu/jrc/en/eurl/ecvam/alternative-methods-toxicity-testing/advisory-bodies/esac" class="ecl-link ecl-link--standalone" >EURL ECVAM Scientific Advisory Committee (ESAC) </a></div><div class="ecl-content-block__description"><div class="ecl"><p>The primary role of the Committee is to carry out high-quality independent peer reviews on validation studies to assess the scientific validity of test methods and specify the capacity and limitations of the proposed methods. The outcomes of the ESAC peer reviews are published as "ESAC Opinions."</p></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 last-item-column last-item"><article class="ecl-navigation-list__item ecl-navigation-list__item--no-border" ><div class="ecl-content-block ecl-navigation-list__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://joint-research-centre.ec.europa.eu/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam/knowledge-sharing-three-rs/knowledge-networks/estaf-eurl-ecvam-stakeholder-forum_en" class="ecl-link ecl-link--standalone" >EURL ECVAM Stakeholder Forum (ESTAF) </a></div><div class="ecl-content-block__description"><div class="ecl"><p>The Forum ensures a close dialogue between non-governmental stakeholders, including parties from industry, academia and civil society organisations.</p></div></div></div></article></div></div></div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5328"></a> <div> <div class="ecl"> <h2 class="ecl-u-type-heading-2">Implementation </h2> </div> <div class="ecl"><p>In line with Article 54(1) of Directive 2010/63/EU, as amended by Regulation (EU) 2019/1010, Member States are required to submit a report on its implementation by 10 November 2023 and every five years thereafter. The Commission must publish a Union overview based on that information within six months.</p><p><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:02012D0707-20140115">Commission Implementing Decision 2012/707/EU (as amended by Decision 2014/11/EU)</a><strong> </strong>in its Annex I describes the specific elements of the Directive that are to be covered by the Member State implementation reports.</p><h4>EU Implementation Reports</h4><p>The <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/16a0a839-8f80-4aef-951b-d49cfe21935e/details?download=true">second EU Implementation Report, SWD(2024)183 final</a>, has been published<u>.</u></p><p>Member States submitted their national implementation reports to the Commission electronically. All Member State submissions can be found <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/c7802ced-a1d7-4015-8fa0-7860a2d7efae?p=1&n=10&sort=name_ASC">here</a>.</p><p>The first <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?qid=1581689520921&uri=CELEX:52020DC0015">EU Implementation Report, COM(2020)15 final</a> is accompanied by a <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?qid=1581689520921&uri=CELEX:52020SC0015">Commission Staff Working Document, SWD(2020)15 final</a>.</p><p>Member States submitted their implementation reports to the Commission, see the <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/5d652b7c-2608-4556-8746-8c7067458b96/details?download=true">EU Survey questionnaire</a> and the <a href="https://ec.europa.eu/eusurvey/publication/Art54AnnexI">Member State submissions to the EU Survey</a>. Additional information complementing the submissions is also available: <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/a467bf69-7230-4951-85f4-f02a7b8db5db/details">Annex - Part I - MS additional submissions</a> and <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/04594d49-0061-4750-a530-1d3402e77e08/details?download=true">Annex - Part II - MS additional submissions</a>.</p><h4>Review of the Directive</h4><p>As required by the Directive, a review of the Directive was undertaken in 2017. The <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?qid=1510219889073&uri=COM:2017:631:FIN">Review Report COM(2017) 631</a> is accompanied by a <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=SWD:2017:353:REV1&from=EN">Commission Staff Working Document SWD(2017) 353</a>. The Staff Working Document provides further insight and contains several recommendations for different stakeholders, with the common aim of improving the attainment of the objectives of the Directive.</p><h4>Article 10 Feasibility Study</h4><p>The capture of non-human primates from the wild gives rise to animal welfare, health, and ethical concerns. To end the capturing of animals from the wild for both scientific and breeding purposes, the Directive has set as one of its aims to allow, after an appropriate transition period, only the use of non-human primates that are the offspring of animals which have themselves been bred in captivity, or that are sourced from self-sustaining colonies.</p><p>A <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/0ab3070f-18b6-4a58-b1f7-cb980a529cfb/details?download=true" class="ecl-link">feasibility study (2017)</a> was conducted to consider progress towards this aim. Considering the current and projected demand and supply of the non-human primate species used, and impacts on the animal welfare and health, the conclusions of the feasibility study do not support altering the dates set out in the Directive.</p><p>A <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/071d3900-13f9-4ab9-b888-11ae93a4fe15/details?download=true" class="ecl-link">second feasibility study (2022)</a> concludes that at this time, it is not possible to determine if or whether the aspiration of sourcing non-human primates only from self-sustaining colonies will be achieved in the future. With the recent changes in use, availability, demand and breeding practices in some centres, it is unlikely to be achieved for all commonly used non-human primate species in the foreseeable future.</p><h4>Statistical reports</h4><p>The <a href="/topics/chemicals/animals-science/statistics-and-non-technical-project-summaries_en" class="ecl-link">ALURES Statistical EU Database</a> contains data on the use of animals for scientific purposes collected by the Member States and submitted to the European Commission annually.</p><p>The Commission also provides an annual summary report of the data submitted by Member States. These data provide an improved understanding of where and how animals are still used in science today and will help identify areas in which efforts for the development and validation of alternative approaches need to be intensified.</p></div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5656"></a> <div class="ecl-accordion" data-ecl-auto-init="Accordion" data-ecl-accordion ><div class="ecl-accordion__item"><h3 class="ecl-accordion__title" id="paragraph-5656-0-title"><button type="button" class="ecl-accordion__toggle" data-ecl-accordion-toggle aria-controls="paragraph-5656-0-content" ><span class="ecl-accordion__toggle-flex"><span class="ecl-accordion__toggle-title">From 2015</span><span class="ecl-accordion__toggle-indicator"><svg class="ecl-icon ecl-icon--s ecl-accordion__toggle-icon" focusable="false" aria-hidden="true" data-ecl-accordion-icon><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#plus"></use></svg><svg class="ecl-icon ecl-icon--s ecl-accordion__toggle-icon" focusable="false" aria-hidden="true" data-ecl-accordion-icon><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#minus"></use></svg></span></span></button></h3><div class="ecl-accordion__content" hidden id="paragraph-5656-0-content" role="region" aria-labelledby="paragraph-5656-0-title" ><div class="ecl"><p>The first EU summary report, under Directive 2010/63/EU, on the statistics on the use of animals for scientific purposes by the Member States of the Union covers data from three years, 2015-2017. From 2018 onwards, EU summary reports will be published annually.</p><ul type="disc"><li><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/051e5787-7746-46cf-8a0d-310f84fd1900/details?download=true"><strong>2022 Statistical Report, SWD(2024) 185 final</strong></a> providing data from 27 Members States and Norway.</li><li><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/95702512-3850-4b45-97d6-ef6b5bcdecf6/details?download=true"><strong>2021 Statistical Report, SWD(2024) 184 final</strong></a> providing data from 27 Members States and Norway.</li><li><strong>2020 Statistical Report</strong>, SWD(2023)84 : <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/10ad28d6-e17e-4367-b459-20883402cfcc/details?download=true" class="ecl-link">Executive summary Parts A and B</a> and <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/c957d77a-7a20-4a7c-9239-c73a833fd873/details?download=true" class="ecl-link">Part C</a> providing data of 2020 from 27 Members States and Norway.</li><li><strong>2019 Statistical Report,</strong> SWD(2022)199: <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/643ae86c-1b15-4bc0-9e0a-711cab63ef59/details?download=true" class="ecl-link">Executive summary Parts A and B</a> and <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/df6cd9d1-4b78-43d9-b4b6-d497c2bdf372/details?download=true" class="ecl-link">Part C</a> providing data of 2019 from 28 Members States and Norway.</li><li><strong>2018 Statistical Report,</strong> SWD(2021)204: <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/e9234275-dd95-44ba-b4c6-8babfb449e78/details?download=true" class="ecl-link">Executive summary Parts A and B</a> and <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/4a711c8c-5d2f-46b4-89ce-43cb5c6023e8/details?download=true" class="ecl-link">Part C</a>. It is important to note that from this summary report onwards, also data from Norway is included. Therefore, this report provides data of 2018 from 28 Member States and Norway.</li><li><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?qid=1581689520921&uri=CELEX:52020DC0016"><strong>2015-2017 Statistical Report,</strong> COM(2020)16 final</a>, covering EU data of 2015-2017 from 28 Member States, accompanied by a <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?qid=1581689520921&uri=CELEX:52020SC0010">Commission Staff Working Document, SWD(2020)10 final</a></li></ul></div></div></div><div class="ecl-accordion__item"><h3 class="ecl-accordion__title" id="paragraph-5656-1-title"><button type="button" class="ecl-accordion__toggle" data-ecl-accordion-toggle aria-controls="paragraph-5656-1-content" ><span class="ecl-accordion__toggle-flex"><span class="ecl-accordion__toggle-title">Until 2011</span><span class="ecl-accordion__toggle-indicator"><svg class="ecl-icon ecl-icon--s ecl-accordion__toggle-icon" focusable="false" aria-hidden="true" data-ecl-accordion-icon><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#plus"></use></svg><svg class="ecl-icon ecl-icon--s ecl-accordion__toggle-icon" focusable="false" aria-hidden="true" data-ecl-accordion-icon><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#minus"></use></svg></span></span></button></h3><div class="ecl-accordion__content" hidden id="paragraph-5656-1-content" role="region" aria-labelledby="paragraph-5656-1-title" ><div class="ecl"><ul><li><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52013DC0859">Seventh Statistical Report</a><u>,</u> COM(2013)859/final, covering EU data of <strong>2011 from 27 Member States</strong>, accompanied by a Staff Working Document, <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52013SC0497">SWD(2013) 497 final</a>.</li><li><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52010DC0511R(01)">Sixth Statistical Report</a>, COM(2010) 511/final 2, covering EU data of<strong> 2008 from 27 Member States</strong>, accompanied by a Staff Working Document, <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52010SC1107">SEC (2010) 1107/final 2</a>.</li><li><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52007DC0675">Fifth Statistical Report</a>, COM/2007/675 final, covering EU data of<strong> 2005 from 25 Member States, </strong>accompanied by a Staff Working Document, <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52007SC1455(01)">SEC (2007) 1455</a>.</li><li><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52005DC0007">Fourth Statistical Report,</a> COM/2005/7 final, covering EU data of<strong> 2002 from 15 Member States,</strong> accompanied by a Staff Working Document, <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/368b5c98-ab3e-43ba-8e7f-9e3effaf5496/details?download=true" class="ecl-link">SEC (2005) 45</a>.</li><li><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52003DC0019">Third Statistical Report,</a> COM/2003/0019 final, covering EU data of <strong>1999 from 15 Member States</strong>.</li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/bdd270d6-3cbd-494b-a1bd-fe64ed6ed52a">Second Statistical Report</a>, COM (1999) 191 final, covering EU data of <strong>1996 from 15 Member States</strong></li><li><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/e9094a82-054e-4793-82a8-1bad973ecc73/details?download=true" class="ecl-link">First Statistical Report</a>, COM (94) 195 final, covering EU data of <strong>1991 from 10 Member States</strong></li></ul></div></div></div></div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5657"></a> <div> <div class="ecl"><h4>National Contact Points</h4><p>The Directive requires all Member States to nominate a national authority serving as contact point for the purposes of this Directive.</p><p>See the <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/0aeaad66-7cab-490a-8395-1cafdee9c8c9/details?download=true" class="ecl-link">contact details for the National Contact Points</a>.</p><h4>National Committees</h4><p>The Directive requires all Member States to establish a national committee for the protection on animals in science. The National Committee advises competent authorities and animal welfare bodies, exchange information and share best practises within the EU.</p><p>See the <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/ae8e9f41-951b-48ea-9159-26ea6033a962/details?download=true" class="ecl-link">contact details for the National Committees</a>.</p><h4>Guidance documents and posters</h4><p>It is important that the Directive on the protection of animals used for scientific purposes is implemented correctly. Therefore guidance material has been developed to help all stakeholders apply the principle of the Directive correctly. These publications aim to significantly improve animal welfare and science by enhancing a common understanding of the Directive's provisions across all Member States of the EU.</p><h4>Guidance documents</h4><ul><li><a href="https://op.europa.eu/en/publication-detail/-/publication/191a69b0-2555-11e9-8d04-01aa75ed71a1/language-en/format-PDF/source-282223752"><u>Animal Welfare Bodies and National Committees</u></a></li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/fca9ae7f-2554-11e9-8d04-01aa75ed71a1/language-en/format-PDF/source-282223752"><u>Education and Training Framework</u></a></li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/7ff424e1-eb8f-11ec-a534-01aa75ed71a1/language-en/format-PDF/source-282223967"><u>Genetically Altered Animals</u></a></li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/afdd3089-2554-11e9-8d04-01aa75ed71a1/language-en/format-PDF/source-282223713"><u>Inspections and Enforcement</u></a></li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/01fb2df2-eb8c-11ec-a534-01aa75ed71a1/language-en/format-PDF/source-search"><u>Non-technical Project Summaries (NTS)</u></a></li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/68ebdc3d-140e-11ef-a251-01aa75ed71a1/language-en/format-PDF/source-search"><u>Results of Retrospective Assessment (Updates to NTS)</u></a></li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/7a2f43a1-2550-11e9-8d04-01aa75ed71a1/language-en/format-PDF/source-282223752"><u>Project Evaluation and Retrospective Assessment</u></a></li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/fe448d22-282f-11e9-8d04-01aa75ed71a1/language-en/format-PDF/source-282223752"><u>Severity Assessment Framework</u></a></li></ul><h4><u>Posters</u></h4><p><u>Posters can be downloaded, printed (up to AO size) and placed in work areas from </u><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/f35bbfad-2c7a-435a-ad4a-a2eda35769a4" class="ecl-link"><u>here</u></a><u>. </u></p><p><u>A </u><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/2d920a5e-f0ff-487c-ad1e-d5a395c3e30e/details?download=true" class="ecl-link"><u>catalogue of published guidance</u></a><u>, provided to the Commission by National Committees has been prepared. The content of the guidance provided by Member State National Committees does not imply a policy position of the European Commission. Only the Court of Justice of the European Union is entitled to interpret EU law with legally binding authority.</u></p><p><u>See also the </u><a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/5418871e-d305-43f5-9475-00f727fa10bf/details?download=true" class="ecl-link"><u>Questions and answers</u></a><u> on the legal understanding of specific provisions of the Directive.</u></p></div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5662"></a> <div class="ecl-content-item-block"><div class="ecl-row"><div class="ecl-content-item-block__title ecl-col-12"><h2 class='ecl-u-type-heading-2'>Tools</h2></div></div><div class="ecl-row"><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 "><article class="ecl-content-item" ><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://environment.ec.europa.eu/topics/chemicals/animals-science/statistics-and-non-technical-project-summaries_en#statistical-database" class="ecl-link ecl-link--standalone" >ALURES Statistical EU Database</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Open access to statistical information on the use of animals in science.</p></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 "><article class="ecl-content-item" ><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://environment.ec.europa.eu/topics/chemicals/animals-science/statistics-and-non-technical-project-summaries_en#project-summaries-database" class="ecl-link ecl-link--standalone" >ALURES Non Technical Summaries EU Database</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Open access to non-technical summaries on the use of animals in science.</p></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 last-item-column"><article class="ecl-content-item" ><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://joint-research-centre.ec.europa.eu/eu-reference-laboratory-alternatives-animal-testing-eurl-ecvam_en" class="ecl-link ecl-link--standalone" >EU Reference Laboratory for alternatives to animal testing (EURL ECVAM)</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Promoting and facilitating the use of non-animal methods in testing and research.</p></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 last-item-column last-item"><article class="ecl-content-item" ><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title" data-ecl-title-link><a href="https://etplas.eu/" class="ecl-link ecl-link--standalone ecl-link--icon" ><span class="ecl-link__label">ETPLAS</span><svg class="ecl-icon ecl-icon--2xs ecl-link__icon" focusable="false" aria-hidden="false" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#external"></use></svg></a></div><div class="ecl-content-block__description"><div class="ecl"><p>Education and training platform for laboratory animal science, including e-modules.</p></div></div></div></article></div></div></div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_6298"></a> <div class="ecl-accordion" data-ecl-auto-init="Accordion" data-ecl-accordion ><div class="ecl-accordion__item"><h3 class="ecl-accordion__title" id="paragraph-6298-0-title"><button type="button" class="ecl-accordion__toggle" data-ecl-accordion-toggle aria-controls="paragraph-6298-0-content" ><span class="ecl-accordion__toggle-flex"><span class="ecl-accordion__toggle-title">EURL ECVAM progress report on the development, validation and regulatory acceptance of alternative methods</span><span class="ecl-accordion__toggle-indicator"><svg class="ecl-icon ecl-icon--s ecl-accordion__toggle-icon" focusable="false" aria-hidden="true" data-ecl-accordion-icon><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#plus"></use></svg><svg class="ecl-icon ecl-icon--s ecl-accordion__toggle-icon" focusable="false" aria-hidden="true" data-ecl-accordion-icon><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#minus"></use></svg></span></span></button></h3><div class="ecl-accordion__content" hidden id="paragraph-6298-0-content" role="region" aria-labelledby="paragraph-6298-0-title" ><div class="ecl"><ul type="disc"><li><a href="https://op.europa.eu/en/publication-detail/-/publication/3226c1c9-e020-11ee-a5fe-01aa75ed71a1/language-en/format-PDF/source-313250187">EURL ECVAM status report on non-animal methods in science and regulation</a> (2023)</li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/71ab691d-c9f6-11ed-a05c-01aa75ed71a1/language-en/format-PDF/source-286246107" class="ecl-link">EURL ECVAM status report on non-animal methods in science and regulation</a> (2022)</li><li><a href="https://publications.jrc.ec.europa.eu/repository/handle/JRC127780" class="ecl-link">EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2021)</li><li><a href="https://publications.jrc.ec.europa.eu/repository/handle/JRC123531" class="ecl-link">EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2020)</li><li><a href="https://publications.jrc.ec.europa.eu/repository/handle/JRC119292" class="ecl-link">EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2019)</li><li><a href="https://publications.jrc.ec.europa.eu/repository/handle/JRC113594" class="ecl-link">EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2018)</li><li><a href="https://publications.jrc.ec.europa.eu/repository/handle/JRC108831" class="ecl-link">EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2017)</li><li><a href="https://publications.jrc.ec.europa.eu/repository/handle/JRC103522" class="ecl-link">EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2016)</li><li><a href="https://bookshop.europa.eu/en/eurl-ecvam-status-report-on-the-development-validation-and-regulatory-acceptance-of-alternative-methods-and-approaches-2015--pbLBNA27474/" class="ecl-link">EURL ECVAM status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2015)</li><li><a href="https://bookshop.europa.eu/en/eurl-ecvam-status-report-on-the-development-validation-and-regulatory-acceptance-of-alternative-methods-and-approaches-2013-april-2014--pbLBNA26702/" class="ecl-link">EURL ECVAM, status report on the development, validation and regulatory acceptance of alternative methods and approaches</a> (2013-April 2014)</li><li><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52013DC0135" class="ecl-link">Communication from the Commission on the animal testing and marketing ban and on the state of play in relation to alternative methods in the field of cosmetics</a> (2013)  </li><li><a href="https://op.europa.eu/en/publication-detail/-/publication/4289db93-bfce-4a18-91e0-18f56e4376df/language-en/format-PDF/source-286245927" class="ecl-link">EURL ECVAM progress report on the development, validation and regulatory acceptance of alternative methods </a>(2010-2013)</li></ul></div></div></div></div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5340"></a> <div> <div class="ecl"> <h2 class="ecl-u-type-heading-2">Related links </h2> </div> <div class="ecl"><p><strong>Main laws: </strong><a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32010L0063">Directive 2010/63/EU</a>, <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=uriserv:OJ.L_.2020.129.01.0016.01.ENG&toc=OJ:L:2020:129:TOC">Commission Implementing Decision (EU) 2020/569</a>, <a href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A32007H0526">Recommendation 2007/526/EC</a></p><p><strong>Related topics</strong>: <a href="https://single-market-economy.ec.europa.eu/sectors/cosmetics/ban-animal-testing_en">Cosmetics Regulation,</a> <a href="https://environment.ec.europa.eu/topics/chemicals/reach-regulation_en">REACH Regulation</a><u>, </u><a href="https://food.ec.europa.eu/plants/pesticides_en">Pesticides</a><u>, </u><a href="https://health.ec.europa.eu/biocides/overview_en">Biocides,</a> <a href="https://health.ec.europa.eu/medicinal-products/pharmaceutical-strategy-europe_en">Pharmaceuticals</a></p><p><strong>Related EU agencies</strong>: <a href="https://echa.europa.eu/animal-testing-under-reach">European Chemicals Agency</a>, <a href="https://www.ema.europa.eu/en/human-regulatory/research-development/ethical-use-animals-medicine-testing">European Medicines Agency</a>, <a href="https://www.efsa.europa.eu/en/topics/topic/alternatives-animal-testing">European Food Safety Authority</a></p></div> </div> </div> <div> <a id="paragraph_5341"></a> <div> <div class="ecl"> <h2 class="ecl-u-type-heading-2">Contact </h2> </div> <div class="ecl"><p>For questions about EU environmental policy, please contact <a href="https://european-union.europa.eu/contact-eu_en">Europe Direct</a>.</p><p>See also the <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/0aeaad66-7cab-490a-8395-1cafdee9c8c9/details?download=true" class="ecl-link">contact details for Member State authorities</a> and the <a href="https://circabc.europa.eu/ui/group/8ee3c69a-bccb-4f22-89ca-277e35de7c63/library/ad6fc22a-bb6b-4be7-b8dc-e25da5f2fd19/details?download=true" class="ecl-link">Member State contact points for the PARERE Network.</a></p><p> </p></div> </div> </div> </div> </div> </div> </div> </article> </div> <div data-inpage-navigation-source-area="h2"> <div id="block-ewcms-theme-chemicalsnewscustomblock"> <div class="ecl-u-mb-2xl"> <a id="paragraph_7074"></a> <div> <div id="block-relatedstories" class="ecl-u-mt-l"> <div class="ecl-content-item-block"><div class="ecl-row"><div class="ecl-content-item-block__title ecl-col-12"><h2 class='ecl-u-type-heading-2'>Related Stories</h2></div></div><div class="ecl-row"><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 "><article class="ecl-card" ><picture class="ecl-picture ecl-picture--zoom ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="https://environment.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2024-12/GettyImages-1680302937.jpg?h=be392151&itok=Sc9LOJMg" alt="" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">News article</li><li class="ecl-content-block__primary-meta-item"><time datetime="2024-12-19T12:00:00Z">19 December 2024</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="https://food.ec.europa.eu/food-safety-news-0/commission-adopts-ban-bisphenol-food-contact-materials-2024-12-19_en" class="ecl-link ecl-link--standalone" >Commission adopts ban of Bisphenol A in food contact materials</a></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 "><article class="ecl-card" ><picture class="ecl-picture ecl-picture--zoom ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="https://environment.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2024-12/GettyImages-1195504200.jpg?h=179d94f5&itok=1_D9GGer" alt="" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">News article</li><li class="ecl-content-block__primary-meta-item"><time datetime="2024-12-10T12:00:00Z">10 December 2024</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="/news/revised-chemical-labelling-regulation-enters-force-2024-12-10_en" class="ecl-link ecl-link--standalone" >Revised Regulation on Classification, Labelling and Packaging of Chemicals enters into force</a></div><ul class="ecl-content-block__secondary-meta-container"><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#clock"></use></svg><span class="ecl-content-block__secondary-meta-label">3 min read</span></li></ul></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 "><article class="ecl-card" ><picture class="ecl-picture ecl-picture--zoom ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="https://environment.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2024-09/GettyImages-518247414.jpg?h=1c953990&itok=ES3yn73n" alt="" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Press release</li><li class="ecl-content-block__primary-meta-item"><time datetime="2024-09-19T12:00:00Z">19 September 2024</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="https://ec.europa.eu/commission/presscorner/detail/en/ip_24_4763" class="ecl-link ecl-link--standalone" >Commission restricts use of sub-group of PFAS chemicals to protect human health and environment</a></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 last-item-column"><article class="ecl-card" ><picture class="ecl-picture ecl-picture--zoom ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="https://environment.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2024-07/GettyImages-1873048874.jpg?h=62bdbd82&itok=-9gK0rvJ" alt="" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">News announcement</li><li class="ecl-content-block__primary-meta-item"><time datetime="2024-07-30T12:00:00Z">30 July 2024</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="/news/revised-mercury-regulation-enters-force-2024-07-30_en" class="ecl-link ecl-link--standalone" >Towards a mercury-free environment: Revised Mercury Regulation enters into force </a></div><ul class="ecl-content-block__secondary-meta-container"><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#clock"></use></svg><span class="ecl-content-block__secondary-meta-label">1 min read</span></li></ul></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 last-item-column"><article class="ecl-card" ><picture class="ecl-picture ecl-picture--zoom ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="https://environment.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2023-10/NA1512_shutterstock_1237020829.jpg?itok=G8XQntbW" alt="" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Press release</li><li class="ecl-content-block__primary-meta-item"><time datetime="2024-04-22T12:00:00Z">22 April 2024</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="https://ec.europa.eu/commission/presscorner/detail/en/ip_24_2151" class="ecl-link ecl-link--standalone" >Commission defines principles on limiting most harmful chemicals to essential uses</a></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 last-item-column last-item"><article class="ecl-card" ><picture class="ecl-picture ecl-picture--zoom ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="https://environment.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2023-07/GettyImages-97995414.jpg?h=02ce9656&itok=iXSySepX" alt="" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Press release</li><li class="ecl-content-block__primary-meta-item"><time datetime="2024-02-08T12:00:00Z">8 February 2024</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="https://ec.europa.eu/commission/presscorner/detail/en/IP_24_679" class="ecl-link ecl-link--standalone" >Commission welcomes political agreement on toxic mercury ban</a></div></div></div></article></div></div><div class="ecl-row"><div class="ecl-content-item-block__button ecl-col-12"><div class="ecl-u-clearfix ecl-u-pv-m"><a href="/news_en?f%5B0%5D=oe_news_subject%3Ahttp%3A//data.europa.eu/uxp/3667&f%5B1%5D=oe_news_subject%3Ahttp%3A//data.europa.eu/uxp/c_e5d85c14" class="ecl-link ecl-link--standalone ecl-link--icon" ><span class="ecl-link__label">See all</span><svg class="ecl-icon ecl-icon--xs ecl-icon--rotate-180 ecl-link__icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#arrow-left"></use></svg></a></div></div></div></div> </div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_9162"></a> <div> <div id="block-relatedevents" class="ecl-u-mt-l"> <div class="ecl-content-item-block"><div class="ecl-row"><div class="ecl-content-item-block__title ecl-col-12"><h2 class='ecl-u-type-heading-2'>Related Events</h2></div></div><div class="ecl-row"><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 last-item-column"><article class="ecl-card" ><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Conferences and summits</li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="/events/6th-annual-forum-endocrine-disruptors-2024-10-29_en" class="ecl-link ecl-link--standalone" >6th Annual Forum on Endocrine Disruptors</a></div><ul class="ecl-content-block__secondary-meta-container"><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#calendar"></use></svg><span class="ecl-content-block__secondary-meta-label">Tuesday 29 October 2024, 10:00 - Wednesday 30 October 2024, 14:00 (GMT+0100)</span></li><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#location"></use></svg><span class="ecl-content-block__secondary-meta-label">Brussels, Belgium</span></li></ul></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 last-item-column"><article class="ecl-card" ><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Training and workshops</li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="/events/roadmap-towards-phasing-out-animal-testing-chemical-safety-assessments-2024-10-25_en" class="ecl-link ecl-link--standalone" >Save the date - 2nd workshop on Roadmap towards phasing out animal testing for chemical safety assessments</a></div><ul class="ecl-content-block__secondary-meta-container"><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#calendar"></use></svg><span class="ecl-content-block__secondary-meta-label">Friday 25 October 2024, 11:00 - 19:00 (GMT+0200)</span></li><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#location"></use></svg><span class="ecl-content-block__secondary-meta-label">Brussels, Belgium</span></li></ul></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-4 last-item-column last-item"><article class="ecl-card" ><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Conferences and summits</li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="https://cinea.ec.europa.eu/news-events/events/life-concert-reach-final-event-2023-06-19_en" class="ecl-link ecl-link--standalone" >LIFE CONCERT REACH final event </a></div><ul class="ecl-content-block__secondary-meta-container"><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#calendar"></use></svg><span class="ecl-content-block__secondary-meta-label">Monday 19 June 2023, 11:00 - Tuesday 20 June 2023, 15:20 (GMT+0200)</span></li><li class="ecl-content-block__secondary-meta-item"><svg class="ecl-icon ecl-icon--s ecl-content-block__secondary-meta-icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#location"></use></svg><span class="ecl-content-block__secondary-meta-label">Italy</span></li></ul></div></div></article></div></div><div class="ecl-row"><div class="ecl-content-item-block__button ecl-col-12"><div class="ecl-u-clearfix ecl-u-pv-m"><a href="https://ec.europa.eu/environment/all-events_en" class="ecl-link ecl-link--standalone ecl-link--icon" ><span class="ecl-link__label">See all</span><svg class="ecl-icon ecl-icon--xs ecl-icon--rotate-180 ecl-link__icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#arrow-left"></use></svg></a></div></div></div></div> </div> </div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_9163"></a> <div> <div id="block-relatedpublications" class="ecl-u-mt-l"> <div class="ecl-content-item-block"><div class="ecl-row"><div class="ecl-content-item-block__title ecl-col-12"><h2 class='ecl-u-type-heading-2'>Related Publications</h2></div></div><div class="ecl-row"><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 "><article class="ecl-content-item" ><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Communication</li><li class="ecl-content-block__primary-meta-item"><time datetime="2024-04-22T12:00:00Z">22 April 2024</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="https://op.europa.eu/en/publication-detail/-/publication/90926c62-0365-11ef-a251-01aa75ed71a1/language-en/format-PDF/source-319809317" class="ecl-link ecl-link--standalone" >Communication from the Commission: Guiding criteria and principles for the essential use concept in EU legislation dealing with chemicals</a></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 "><article class="ecl-content-item" ><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Report</li><li class="ecl-content-block__primary-meta-item"><time datetime="2023-12-07T12:00:00Z">7 December 2023</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="/publications/report-review-directive-restriction-use-certain-hazardous-substances-electrical-and-electronic_en" class="ecl-link ecl-link--standalone" >Report on the review of the Directive on the restriction of the use of certain hazardous substances in electrical and electronic equipment</a></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 last-item-column last-item"><article class="ecl-content-item" ><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><ul class="ecl-content-block__primary-meta-container"><li class="ecl-content-block__primary-meta-item">Proposal for a regulation</li><li class="ecl-content-block__primary-meta-item"><time datetime="2023-12-07T12:00:00Z">7 December 2023</time></li></ul><div class="ecl-content-block__title" data-ecl-title-link><a href="/publications/proposal-regulation-establishing-common-data-platform-chemicals_en" class="ecl-link ecl-link--standalone" >Proposal for a Regulation establishing a common data platform on chemicals</a></div></div></article></div></div><div class="ecl-u-border-color-neutral ecl-u-border-width-1 ecl-u-border-top"></div><div class="ecl-row"><div class="ecl-content-item-block__button ecl-col-12"><div class="ecl-u-clearfix ecl-u-pv-m"><a 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