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Noradrenalin - Wikipedija, prosta enciklopedija
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class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Uvod</div> </a> </li> <li id="toc-Biosinteza" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Biosinteza"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Biosinteza</span> </div> </a> <ul id="toc-Biosinteza-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Uporaba_v_terapiji" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Uporaba_v_terapiji"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Uporaba v terapiji</span> </div> </a> <button aria-controls="toc-Uporaba_v_terapiji-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon 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class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Vklopi kazalo vsebine" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Vklopi kazalo vsebine</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Noradrenalin</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="P9jdi na članek v drugem jeziku. Na voljo v 61 jezikih." > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-61" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">61 jezikov</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar badge-Q17437798 badge-goodarticle mw-list-item" title="dober članek"><a href="https://ar.wikipedia.org/wiki/%D9%86%D9%88%D8%B1%D8%A5%D8%A8%D9%8A%D9%86%D9%81%D8%B1%D9%8A%D9%86" title="نورإبينفرين – arabščina" lang="ar" hreflang="ar" data-title="نورإبينفرين" data-language-autonym="العربية" data-language-local-name="arabščina" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – azerbajdžanščina" lang="az" hreflang="az" data-title="Noradrenalin" data-language-autonym="Azərbaycanca" data-language-local-name="azerbajdžanščina" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%86%D9%88%D8%B1%D8%A6%D9%BE%DB%8C%D9%86%D8%A6%D9%81%D8%B1%DB%8C%D9%86" title="نورئپینئفرین – South Azerbaijani" lang="azb" hreflang="azb" data-title="نورئپینئفرین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-be mw-list-item"><a href="https://be.wikipedia.org/wiki/%D0%9D%D0%BE%D1%80%D0%B0%D0%B4%D1%80%D1%8D%D0%BD%D0%B0%D0%BB%D1%96%D0%BD" title="Норадрэналін – beloruščina" lang="be" hreflang="be" data-title="Норадрэналін" data-language-autonym="Беларуская" data-language-local-name="beloruščina" class="interlanguage-link-target"><span>Беларуская</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9D%D0%BE%D1%80%D0%B0%D0%B4%D1%80%D0%B5%D0%BD%D0%B0%D0%BB%D0%B8%D0%BD" title="Норадреналин – bolgarščina" lang="bg" hreflang="bg" data-title="Норадреналин" data-language-autonym="Български" data-language-local-name="bolgarščina" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Norepinefrin" title="Norepinefrin – bosanščina" lang="bs" hreflang="bs" data-title="Norepinefrin" data-language-autonym="Bosanski" data-language-local-name="bosanščina" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – katalonščina" lang="ca" hreflang="ca" data-title="Noradrenalina" data-language-autonym="Català" data-language-local-name="katalonščina" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – češčina" lang="cs" hreflang="cs" data-title="Noradrenalin" data-language-autonym="Čeština" data-language-local-name="češčina" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Norepineffrin" title="Norepineffrin – valižanščina" lang="cy" hreflang="cy" data-title="Norepineffrin" data-language-autonym="Cymraeg" data-language-local-name="valižanščina" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – danščina" lang="da" hreflang="da" data-title="Noradrenalin" data-language-autonym="Dansk" data-language-local-name="danščina" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – nemščina" lang="de" hreflang="de" data-title="Noradrenalin" data-language-autonym="Deutsch" data-language-local-name="nemščina" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-dv mw-list-item"><a href="https://dv.wikipedia.org/wiki/%DE%82%DE%AF%DE%87%DE%AC%DE%91%DE%B0%DE%83%DE%AC%DE%82%DE%A6%DE%8D%DE%A8%DE%82%DE%B0" title="ނޯއެޑްރެނަލިން – diveščina" lang="dv" hreflang="dv" data-title="ނޯއެޑްރެނަލިން" data-language-autonym="ދިވެހިބަސް" data-language-local-name="diveščina" class="interlanguage-link-target"><span>ދިވެހިބަސް</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%9D%CE%BF%CF%81%CE%B5%CF%80%CE%B9%CE%BD%CE%B5%CF%86%CF%81%CE%AF%CE%BD%CE%B7" title="Νορεπινεφρίνη – grščina" lang="el" hreflang="el" data-title="Νορεπινεφρίνη" data-language-autonym="Ελληνικά" data-language-local-name="grščina" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en badge-Q17437798 badge-goodarticle mw-list-item" title="dober članek"><a href="https://en.wikipedia.org/wiki/Norepinephrine" title="Norepinephrine – angleščina" lang="en" hreflang="en" data-title="Norepinephrine" data-language-autonym="English" data-language-local-name="angleščina" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Noradrenalino" title="Noradrenalino – esperanto" lang="eo" hreflang="eo" data-title="Noradrenalino" data-language-autonym="Esperanto" data-language-local-name="esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – španščina" lang="es" hreflang="es" data-title="Noradrenalina" data-language-autonym="Español" data-language-local-name="španščina" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Noradrenaliin" title="Noradrenaliin – estonščina" lang="et" hreflang="et" data-title="Noradrenaliin" data-language-autonym="Eesti" data-language-local-name="estonščina" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – baskovščina" lang="eu" hreflang="eu" data-title="Noradrenalina" data-language-autonym="Euskara" data-language-local-name="baskovščina" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%86%D9%88%D8%B1%D8%A7%D9%BE%DB%8C%E2%80%8C%D9%86%D9%81%D8%B1%DB%8C%D9%86" title="نوراپینفرین – perzijščina" lang="fa" hreflang="fa" data-title="نوراپینفرین" data-language-autonym="فارسی" data-language-local-name="perzijščina" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Noradrenaliini" title="Noradrenaliini – finščina" lang="fi" hreflang="fi" data-title="Noradrenaliini" data-language-autonym="Suomi" data-language-local-name="finščina" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Noradr%C3%A9naline" title="Noradrénaline – francoščina" lang="fr" hreflang="fr" data-title="Noradrénaline" data-language-autonym="Français" data-language-local-name="francoščina" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Noraidr%C3%A9anail%C3%ADn" title="Noraidréanailín – irščina" lang="ga" hreflang="ga" data-title="Noraidréanailín" data-language-autonym="Gaeilge" data-language-local-name="irščina" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – galicijščina" lang="gl" hreflang="gl" data-title="Noradrenalina" data-language-autonym="Galego" data-language-local-name="galicijščina" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A0%D7%95%D7%A8%D7%90%D7%93%D7%A8%D7%A0%D7%9C%D7%99%D7%9F" title="נוראדרנלין – hebrejščina" lang="he" hreflang="he" data-title="נוראדרנלין" data-language-autonym="עברית" data-language-local-name="hebrejščina" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – hrvaščina" lang="hr" hreflang="hr" data-title="Noradrenalin" data-language-autonym="Hrvatski" data-language-local-name="hrvaščina" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – madžarščina" lang="hu" hreflang="hu" data-title="Noradrenalin" data-language-autonym="Magyar" data-language-local-name="madžarščina" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%86%D5%B8%D6%80%D5%A1%D5%A4%D6%80%D5%A5%D5%B6%D5%A1%D5%AC%D5%AB%D5%B6" title="Նորադրենալին – armenščina" lang="hy" hreflang="hy" data-title="Նորադրենալին" data-language-autonym="Հայերեն" data-language-local-name="armenščina" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – indonezijščina" lang="id" hreflang="id" data-title="Noradrenalin" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonezijščina" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-is mw-list-item"><a href="https://is.wikipedia.org/wiki/Noradrenal%C3%ADn" title="Noradrenalín – islandščina" lang="is" hreflang="is" data-title="Noradrenalín" data-language-autonym="Íslenska" data-language-local-name="islandščina" class="interlanguage-link-target"><span>Íslenska</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – italijanščina" lang="it" hreflang="it" data-title="Noradrenalina" data-language-autonym="Italiano" data-language-local-name="italijanščina" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%8E%E3%83%AB%E3%82%A2%E3%83%89%E3%83%AC%E3%83%8A%E3%83%AA%E3%83%B3" title="ノルアドレナリン – japonščina" lang="ja" hreflang="ja" data-title="ノルアドレナリン" data-language-autonym="日本語" data-language-local-name="japonščina" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EB%85%B8%EB%A5%B4%EC%97%90%ED%94%BC%EB%84%A4%ED%94%84%EB%A6%B0" title="노르에피네프린 – korejščina" lang="ko" hreflang="ko" data-title="노르에피네프린" data-language-autonym="한국어" data-language-local-name="korejščina" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ks mw-list-item"><a href="https://ks.wikipedia.org/wiki/%D9%86%D9%88%D8%B1%D8%A7%DB%8C%D9%BE%DB%8C%D9%86%DB%8C%D9%81%D8%B1%DB%8C%D9%86" title="نورایپینیفرین – kašmirščina" lang="ks" hreflang="ks" data-title="نورایپینیفرین" data-language-autonym="कॉशुर / کٲشُر" data-language-local-name="kašmirščina" class="interlanguage-link-target"><span>कॉशुर / کٲشُر</span></a></li><li class="interlanguage-link interwiki-ky mw-list-item"><a href="https://ky.wikipedia.org/wiki/%D0%9D%D0%BE%D1%80%D0%B0%D0%B4%D1%80%D0%B5%D0%BD%D0%B0%D0%BB%D0%B8%D0%BD" title="Норадреналин – kirgiščina" lang="ky" hreflang="ky" data-title="Норадреналин" data-language-autonym="Кыргызча" data-language-local-name="kirgiščina" class="interlanguage-link-target"><span>Кыргызча</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – latinščina" lang="la" hreflang="la" data-title="Noradrenalina" data-language-autonym="Latina" data-language-local-name="latinščina" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Noradrenalinas" title="Noradrenalinas – litovščina" lang="lt" hreflang="lt" data-title="Noradrenalinas" data-language-autonym="Lietuvių" data-language-local-name="litovščina" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Noradrenal%C4%ABns" title="Noradrenalīns – latvijščina" lang="lv" hreflang="lv" data-title="Noradrenalīns" data-language-autonym="Latviešu" data-language-local-name="latvijščina" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%9D%D0%BE%D1%80%D0%B0%D0%B4%D1%80%D0%B5%D0%BD%D0%B0%D0%BB%D0%B8%D0%BD" title="Норадреналин – makedonščina" lang="mk" hreflang="mk" data-title="Норадреналин" data-language-autonym="Македонски" data-language-local-name="makedonščina" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%A8%E0%B5%8B%E0%B5%BC_%E0%B4%85%E0%B4%A1%E0%B5%8D%E0%B4%B0%E0%B4%BF%E0%B4%A8%E0%B4%BE%E0%B4%B2%E0%B4%BF%E0%B5%BB" title="നോർ അഡ്രിനാലിൻ – malajalamščina" lang="ml" hreflang="ml" data-title="നോർ അഡ്രിനാലിൻ" data-language-autonym="മലയാളം" data-language-local-name="malajalamščina" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Norepinefrina" title="Norepinefrina – malajščina" lang="ms" hreflang="ms" data-title="Norepinefrina" data-language-autonym="Bahasa Melayu" data-language-local-name="malajščina" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Noradrenaline" title="Noradrenaline – nizozemščina" lang="nl" hreflang="nl" data-title="Noradrenaline" data-language-autonym="Nederlands" data-language-local-name="nizozemščina" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – knjižna norveščina" lang="nb" hreflang="nb" data-title="Noradrenalin" data-language-autonym="Norsk bokmål" data-language-local-name="knjižna norveščina" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%A8%E0%AC%B0%E0%AD%8D%E2%80%8C%E0%AC%8F%E0%AC%AA%E0%AC%BF%E0%AC%A8%E0%AD%87%E0%AC%AB%E0%AD%8D%E0%AC%B0%E0%AC%BF%E0%AC%A8" title="ନର୍ଏପିନେଫ୍ରିନ – odijščina" lang="or" hreflang="or" data-title="ନର୍ଏପିନେଫ୍ରିନ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="odijščina" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – poljščina" lang="pl" hreflang="pl" data-title="Noradrenalina" data-language-autonym="Polski" data-language-local-name="poljščina" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – portugalščina" lang="pt" hreflang="pt" data-title="Noradrenalina" data-language-autonym="Português" data-language-local-name="portugalščina" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Noradrenalin%C4%83" title="Noradrenalină – romunščina" lang="ro" hreflang="ro" data-title="Noradrenalină" data-language-autonym="Română" data-language-local-name="romunščina" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9D%D0%BE%D1%80%D0%B0%D0%B4%D1%80%D0%B5%D0%BD%D0%B0%D0%BB%D0%B8%D0%BD" title="Норадреналин – ruščina" lang="ru" hreflang="ru" data-title="Норадреналин" data-language-autonym="Русский" data-language-local-name="ruščina" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – srbohrvaščina" lang="sh" hreflang="sh" data-title="Noradrenalin" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="srbohrvaščina" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Noradrenal%C3%ADn" title="Noradrenalín – slovaščina" lang="sk" hreflang="sk" data-title="Noradrenalín" data-language-autonym="Slovenčina" data-language-local-name="slovaščina" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Noradrenalina" title="Noradrenalina – albanščina" lang="sq" hreflang="sq" data-title="Noradrenalina" data-language-autonym="Shqip" data-language-local-name="albanščina" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%9D%D0%BE%D1%80%D0%B0%D0%B4%D1%80%D0%B5%D0%BD%D0%B0%D0%BB%D0%B8%D0%BD" title="Норадреналин – srbščina" lang="sr" hreflang="sr" data-title="Норадреналин" data-language-autonym="Српски / srpski" data-language-local-name="srbščina" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-su mw-list-item"><a href="https://su.wikipedia.org/wiki/Nor%C3%A9pin%C3%A9frin" title="Norépinéfrin – sundanščina" lang="su" hreflang="su" data-title="Norépinéfrin" data-language-autonym="Sunda" data-language-local-name="sundanščina" class="interlanguage-link-target"><span>Sunda</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – švedščina" lang="sv" hreflang="sv" data-title="Noradrenalin" data-language-autonym="Svenska" data-language-local-name="švedščina" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%A8%E0%AE%BE%E0%AE%B0%E0%AF%8D%E0%AE%8E%E0%AE%AA%E0%AE%BF%E0%AE%A8%E0%AF%86%E0%AE%AA%E0%AF%8D%E0%AE%B0%E0%AE%BF%E0%AE%A9%E0%AF%8D" title="நார்எபிநெப்ரின் – tamilščina" lang="ta" hreflang="ta" data-title="நார்எபிநெப்ரின்" data-language-autonym="தமிழ்" data-language-local-name="tamilščina" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%99%E0%B8%AD%E0%B8%A3%E0%B9%8C%E0%B9%80%E0%B8%AD%E0%B8%9E%E0%B8%B4%E0%B9%80%E0%B8%99%E0%B8%9F%E0%B8%A3%E0%B8%B5%E0%B8%99" title="นอร์เอพิเนฟรีน – tajščina" lang="th" hreflang="th" data-title="นอร์เอพิเนฟรีน" data-language-autonym="ไทย" data-language-local-name="tajščina" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – turščina" lang="tr" hreflang="tr" data-title="Noradrenalin" data-language-autonym="Türkçe" data-language-local-name="turščina" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9D%D0%BE%D1%80%D0%B0%D0%B4%D1%80%D0%B5%D0%BD%D0%B0%D0%BB%D1%96%D0%BD" title="Норадреналін – ukrajinščina" lang="uk" hreflang="uk" data-title="Норадреналін" data-language-autonym="Українська" data-language-local-name="ukrajinščina" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – uzbeščina" lang="uz" hreflang="uz" data-title="Noradrenalin" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="uzbeščina" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Noradrenalin" title="Noradrenalin – vietnamščina" lang="vi" hreflang="vi" data-title="Noradrenalin" data-language-autonym="Tiếng Việt" data-language-local-name="vietnamščina" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E5%8E%BB%E7%94%B2%E8%82%BE%E4%B8%8A%E8%85%BA%E7%B4%A0" title="去甲肾上腺素 – wu-kitajščina" lang="wuu" hreflang="wuu" data-title="去甲肾上腺素" data-language-autonym="吴语" data-language-local-name="wu-kitajščina" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%8E%BB%E7%94%B2%E8%82%BE%E4%B8%8A%E8%85%BA%E7%B4%A0" title="去甲肾上腺素 – kitajščina" lang="zh" hreflang="zh" data-title="去甲肾上腺素" data-language-autonym="中文" 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class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Orodja strani"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Videz"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Videz</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">prestavi v stransko letvico</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">skrij</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Iz Wikipedije, proste enciklopedije</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sl" dir="ltr"><table class="infobox bordered" style="border-collapse:collapse; width:22em; text-align:left; ;"> <caption style="text-align:center;">Noradrenalin </caption> <tbody><tr> <td colspan="2" style="text-align:center; padding:2px;"><span typeof="mw:File"><a href="/wiki/Slika:Norepinephrine_structure_with_descriptor.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Norepinephrine_structure_with_descriptor.svg/180px-Norepinephrine_structure_with_descriptor.svg.png" decoding="async" width="180" height="122" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Norepinephrine_structure_with_descriptor.svg/270px-Norepinephrine_structure_with_descriptor.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Norepinephrine_structure_with_descriptor.svg/360px-Norepinephrine_structure_with_descriptor.svg.png 2x" data-file-width="426" data-file-height="288" /></a></span> </td></tr> <tr> <td colspan="2" style="text-align:center; padding:2px;"><span typeof="mw:File"><a href="/wiki/Slika:Norepinephrine-3d-CPK.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/85/Norepinephrine-3d-CPK.png/180px-Norepinephrine-3d-CPK.png" decoding="async" width="180" height="152" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/85/Norepinephrine-3d-CPK.png/270px-Norepinephrine-3d-CPK.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/85/Norepinephrine-3d-CPK.png/360px-Norepinephrine-3d-CPK.png 2x" data-file-width="758" data-file-height="641" /></a></span> </td></tr> <tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Imena </th></tr> <tr> <td colspan="2" style="text-align:left;"><a href="/wiki/Nomenklatura_organske_kemije_IUPAC" title="Nomenklatura organske kemije IUPAC">IUPAC ime</a> <div style="max-width:22em; word-wrap:break-word; padding-left:1.7em;">4-[(1<i>R</i>)-2-amino-1-hidroksietil]benzen-1,2-diol</div> </td></tr> <tr> <td colspan="2" style="text-align:left;">Druga imena <div style="max-width:22em; word-wrap:break-word; padding-left:1.7em;">norepinefrin<sup id="cite_ref-51-41-2_1-0" class="reference"><a href="#cite_note-51-41-2-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></div> </td></tr> <tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Identifikatorji </th></tr> <tr> <td><div style="padding:0.1em 0;line-height:1.2em;"><a href="/wiki/%C5%A0tevilka_CAS" title="Številka CAS">Številka CAS</a></div> </td> <td><style data-mw-deduplicate="TemplateStyles:r5911185">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li><span title="www.commonchemistry.org"><a rel="nofollow" class="external text" href="http://www.commonchemistry.org/ChemicalDetail.aspx?ref=51-41-2">(l) 51-41-2 (l)</a></span></li></ul></div> </td></tr> <tr> <td><div style="padding:0.1em 0;line-height:1.2em;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</div> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=Oc1ccc%28cc1O%29%5BC%40%40H%5D%28O%29CN">Interaktivna slika</a></span></li></ul></div> </td></tr> <tr> <td><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=18357">CHEBI:18357</a></span></li></ul></div> </td></tr> <tr> <td><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="www.ebi.ac.uk"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/ChEMBL1437">ChEMBL1437</a></span></li></ul></div> </td></tr> <tr> <td><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="http://www.chemspider.com/Chemical-Structure.388394.html">388394</a></span></li></ul></div> </td></tr> <tr> <td><a href="/w/index.php?title=DrugBank&action=edit&redlink=1" class="new" title="DrugBank (stran ne obstaja)">DrugBank</a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="www.drugbank.ca"><a rel="nofollow" class="external text" href="https://www.drugbank.ca/drugs/DB00368">DB00368</a></span></li></ul></div> </td></tr> <tr> <td><a href="/wiki/ECHA_InfoCard" class="mw-redirect" title="ECHA InfoCard"><span title="echa.europa.eu">ECHA InfoCard</span></a> </td> <td><a rel="nofollow" class="external text" href="https://echa.europa.eu/substance-information/-/substanceinfo/100.000.088">100.000.088</a> </td></tr> <tr> <td><a href="/wiki/KEGG" title="KEGG">KEGG</a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="www.kegg.jp"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D00076">D00076</a></span></li></ul></div> </td></tr> <tr> <td><div style="padding:0.1em 0;line-height:1.2em;"><a href="/wiki/PubChem" title="PubChem">PubChem</a> <span class="abbr" style="border-bottom: 1px dotted" title="Compound ID">CID</span></div> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/439260">439260</a></span></li></ul></div> </td></tr> <tr> <td><div style="padding:0.1em 0;line-height:1.2em;"><a href="/wiki/CompTox_Chemicals_Dashboard" title="CompTox Chemicals Dashboard">CompTox Dashboard</a> <span style="font-weight:normal">(<span class="abbr" style="border-bottom: 1px dotted" title="U.S. Environmental Protection Agency">EPA</span>)</span></div> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5911185"><div class="plainlist"><ul><li><span title="comptox.epa.gov"><a rel="nofollow" class="external text" href="https://comptox.epa.gov/dashboard/DTXSID5023378">DTXSID5023378</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q186242#P3117" title="Uredite to na Wikipodatkih"><img alt="Uredite to na Wikipodatkih" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></li></ul></div> </td></tr> <tr> <td colspan="2"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold; text-align:left; font-weight:normal; background:transparent;"><div><a href="/wiki/Mednarodni_kemijski_identifikator" title="Mednarodni kemijski identifikator">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.2em 0 0.2em 1.5em; text-align:left;"><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1</div><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">Key: SFLSHLFXELFNJZ-QMMMGPOBSA-N</div></div></li><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.2em 0 0.2em 1.5em; text-align:left;"><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">InChI=1/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1</div><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">Key: SFLSHLFXELFNJZ-QMMMGPOBBL</div></div></li></ul> </div> </td></tr> <tr> <td colspan="2"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold; text-align:left; font-weight:normal; background:transparent;"><div><a href="/wiki/SMILES" title="SMILES">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.2em 0 0.2em 1.6em; word-wrap:break-word; text-indent:-1.5em; text-align:left; font-size:11px; line-height:120%;">Oc1ccc(cc1O)[C@@H](O)CN</div></li></ul> </div> </td></tr> <tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Lastnosti </th></tr> <tr> <td><div style="padding:0.1em 0;line-height:1.2em;"><a href="/wiki/Kemijska_formula" title="Kemijska formula">Kemijska formula</a></div> </td> <td><span title="Carbon">C</span><sub>8</sub><span title="Vodik">H</span><sub>11</sub><span title="Dušik">N</span><span title="Kisik">O</span><sub>3</sub> </td></tr> <tr> <td><a href="/wiki/Molska_masa" title="Molska masa">Molska masa</a> </td> <td>169,18 g/mol    </td></tr> <tr> <td><a href="/wiki/Gostota" title="Gostota">Gostota</a> </td> <td>1,397±0,06 g/cm^3 (20 °C and 760 Torr)<sup id="cite_ref-51-41-2_1-1" class="reference"><a href="#cite_note-51-41-2-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td><a href="/wiki/Tali%C5%A1%C4%8De" title="Tališče">Tališče</a> </td> <td>L: 216,5–218 °C (<i>razpade</i>)<br />D/L: 191 °C (<i>razpade</i>)   </td></tr> <tr> <td><a href="/wiki/Vreli%C5%A1%C4%8De" title="Vrelišče">Vrelišče</a> </td> <td>442,6±40,0 °C (760 Torr)<sup id="cite_ref-51-41-2_1-2" class="reference"><a href="#cite_note-51-41-2-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>   </td></tr> <tr> <td><a href="/wiki/Parni_tlak" title="Parni tlak">Parni tlak</a> </td> <td>1,30e-8 Torr<sup id="cite_ref-51-41-2_1-3" class="reference"><a href="#cite_note-51-41-2-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td><a href="/wiki/Kislost" class="mw-redirect" title="Kislost">Kislost</a> (p<i>K</i><sub>a</sub>) </td> <td>9,57±0,10<sup id="cite_ref-51-41-2_1-4" class="reference"><a href="#cite_note-51-41-2-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </td></tr> <tr> <td colspan="2" style="text-align:left; background:#f8eaba;"><div style="margin:0 auto; text-align:left;"><div style="padding:0.1em 0;line-height:1.2em;">Če ni navedeno drugače, podatki veljajo za material v <a href="/wiki/Standardni_pogoji" title="Standardni pogoji">standardnem stanju</a> pri 25 °C, 100 kPa).</div></div> </td></tr> <tr style="background:#f8eaba; border-top:2px solid transparent;"> <td colspan="2" style="text-align:center;"><a href="https://en.wikipedia.org/wiki/Wikipedia:Chemical_infobox#References" class="extiw" title="en:Wikipedia:Chemical infobox">Sklici infopolja</a> </td></tr> <tr style="background:#f8eaba;"> <td style="width:40%; max-height:1px; border-top:2px solid transparent; border-right:1px solid transparent;"> </td> <td style="width:60%; max-height:1px; border-top:2px solid transparent; border-left:1px solid transparent;"> </td></tr> </tbody></table> <p><b>Noradrenalin</b> (tudi <b>norepinefrin</b>) je <a href="/wiki/%C5%BDiv%C4%8Dni_prena%C5%A1alec" title="Živčni prenašalec">živčni prenašalec</a> <a href="/wiki/Simpati%C4%8Dno_%C5%BEiv%C4%8Devje" title="Simpatično živčevje">simpatičnega živčevja</a> ter <a href="/wiki/Hormon" title="Hormon">hormon</a>, ki ga izloča sredica <a href="/wiki/Nadledvi%C4%8Dna_%C5%BEleza" title="Nadledvična žleza">nadledvičnice</a>. Spada med <a href="/wiki/Kateholamin" class="mw-redirect" title="Kateholamin">kateholamine</a>, enako kot <a href="/wiki/Adrenalin" title="Adrenalin">adrenalin</a>. Njegova <a href="/wiki/Kemijska_formula" title="Kemijska formula">kemijska formula</a> je <a href="/wiki/Ogljik" title="Ogljik">C</a><sub>8</sub><a href="/wiki/Vodik" title="Vodik">H</a><sub>11</sub><a href="/wiki/Du%C5%A1ik" title="Dušik">N</a><a href="/wiki/Kisik" title="Kisik">O</a><sub>3</sub>. Naravni <a href="/w/index.php?title=Stereoizomer&action=edit&redlink=1" class="new" title="Stereoizomer (stran ne obstaja)">stereoizomer</a> je L-(−)-(R)-noradrenalin. </p><p>Poleg <a href="/wiki/Serotonin" title="Serotonin">serotonina</a> je to eden najpomembnejših »hormonov za srečo«. Noradrenalin poživlja možgane, predvsem pa spodbuja sposobnost zaznavanja, motivacijo in energijo. Prav tako učinkuje kot antidepresiv. Novejše raziskave so pokazale<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedija:Navajanje_virov" title="Wikipedija:Navajanje virov"><span title="Ta trditev potrebuje sklice na zanesljive vire. (mesec ni naveden )">navedi vir</span></a></i>]</sup>, da v stresnih situacijah noradrenalin izboljšuje miselno zbranost ter poskrbi poleg tega celo za optimizem in evforijo. Stres nas lahko tako v določenih trenutkih tudi osrečuje in nam daje krila. Tej snovi se lahko tudi zahvalimo, da se še posebno intenzivno spominjamo veselih dogodkov ali močnih čustev. </p><p>Deluje zlasti na <a href="/wiki/Gladko_mi%C5%A1i%C4%8Dje" class="mw-redirect" title="Gladko mišičje">gladko mišičje</a> žil <a href="/wiki/Odvodnica" class="mw-redirect" title="Odvodnica">odvodnic</a>, kjer po vezavi na <a href="/w/index.php?title=Adrenoceptor&action=edit&redlink=1" class="new" title="Adrenoceptor (stran ne obstaja)">adrenergične receptorje</a> povzroči njihovo skrčenje ter posledično porast <a href="/wiki/Krvni_tlak" title="Krvni tlak">krvnega tlaka</a>. Sprošča se iz simpatičnih živčnih končičev. Vpliva tudi na <a href="/wiki/Osrednje_%C5%BEiv%C4%8Devje" title="Osrednje živčevje">osrednje živčevje</a>, in sicer na predele, odgovorne za zvečano pozornost in impulzivnost. Sprošča se zlasti v <a href="/wiki/Stres" title="Stres">stresnih</a> razmerah, zato spada med tako imenovane stresne hormone. Telo pripravi na »boj ali beg« (pospešijo se <a href="/w/index.php?title=Sr%C4%8Dni_utrip&action=edit&redlink=1" class="new" title="Srčni utrip (stran ne obstaja)">srčni utrip</a>, <a href="/w/index.php?title=Glikogenoliza&action=edit&redlink=1" class="new" title="Glikogenoliza (stran ne obstaja)">glikogenoliza</a>, <a href="/w/index.php?title=Glukoneogeneza&action=edit&redlink=1" class="new" title="Glukoneogeneza (stran ne obstaja)">glukoneogeneza</a>, poveča se mišična pripravljenost ...). V osrednjem živčevju se sprošča v predelu <a href="/w/index.php?title=Srednji_mo%C5%BEgani&action=edit&redlink=1" class="new" title="Srednji možgani (stran ne obstaja)">srednjih možganov</a>, ki se imenuje <a href="/w/index.php?title=Locus_coeruleus&action=edit&redlink=1" class="new" title="Locus coeruleus (stran ne obstaja)">locus coeruleus</a>. Noradrenalin se veže na adrenergične receptorje (adrenoceptorje), in sicer na obe podvrsti teh receptorjev: α in β. </p><p>Od adrenalina se strukturno razlikuje le po odsotni metilni skupini na <a href="/wiki/Amin" title="Amin">aminskem</a> dušiku, kar pove že njegovo ime (<i>nor</i> je okrajšava za <i>N ohne Radikal</i>, kar v <a href="/wiki/Nem%C5%A1%C4%8Dina" title="Nemščina">nemščini</a> pomeni N (dušik) brez radikala, torej v tem primeru brez metilne skupine). </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Biosinteza">Biosinteza</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Noradrenalin&veaction=edit&section=1" title="Uredi razdelek: Biosinteza" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Noradrenalin&action=edit&section=1" title="Urejanje izvorne kode razdelka: Biosinteza"><span>uredi kodo</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Noradrenalin se v telesu proizvaja v sredici nadledvičnice iz <a href="/wiki/Aminokislina" title="Aminokislina">aminokisline</a> <a href="/wiki/Tirozin" title="Tirozin">tirozin</a> z več <a href="/wiki/Encim" title="Encim">encimsko</a> vodenimi reakcijami. Najprej nastane z <a href="/wiki/Oksidacija" class="mw-redirect" title="Oksidacija">oksidacijo</a> iz tirozina <a href="/wiki/L-DOPA" class="mw-redirect" title="L-DOPA">dihidroksifenilalanin (L-DOPA)</a>, le-ta se nato <a href="/w/index.php?title=Dekarboksilacija&action=edit&redlink=1" class="new" title="Dekarboksilacija (stran ne obstaja)">dekarboksilira</a> do živčnega prenašalca <a href="/wiki/Dopamin" title="Dopamin">dopamina</a>. Dopamin se z β-oksidacijo pretvori v noradrenalin. Iz noradrenalina lahko z metiliranjem aminskega dušika nastane adrenalin, kar katalizira encim N-metiltransferaza. </p> <div class="mw-heading mw-heading2"><h2 id="Uporaba_v_terapiji">Uporaba v terapiji</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Noradrenalin&veaction=edit&section=2" title="Uredi razdelek: Uporaba v terapiji" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Noradrenalin&action=edit&section=2" title="Urejanje izvorne kode razdelka: Uporaba v terapiji"><span>uredi kodo</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Noradrenalin se kot <a href="/wiki/Zdravilo" title="Zdravilo">zdravilo</a> uporablja pri naslednjih obolenjih: </p> <ul><li><a href="/wiki/Septi%C4%8Dni_%C5%A1ok" title="Septični šok">septični šok</a>,</li> <li><a href="/wiki/Anafilakti%C4%8Dni_%C5%A1ok" title="Anafilaktični šok">anafilaktični šok</a>,</li> <li>zastrupitev z <a href="/wiki/Vazodilatator" title="Vazodilatator">vazodilatatorji</a>.</li></ul> <p>Pri tem se daje predvsem <a href="/wiki/Intravenska_aplikacija" class="mw-redirect" title="Intravenska aplikacija">intravensko</a>, in sicer v zelo nizkih <a href="/wiki/Odmerek" title="Odmerek">odmerkih</a>, da ne pride do okvare črpalne sposobnosti <a href="/wiki/Srce" title="Srce">srca</a>. <a href="/w/index.php?title=Lokalna_aplikacija&action=edit&redlink=1" class="new" title="Lokalna aplikacija (stran ne obstaja)">Lokalno</a> se daje za preprečevanje krvavitev med <a href="/wiki/Operacija_(medicina)" title="Operacija (medicina)">operacijami</a>. Često je kar v kombinaciji z <a href="/wiki/Lokalni_anestetik" title="Lokalni anestetik">lokalnim anestetikom</a>. Kot alternativna učinkovina se uporablja adrenalin. </p> <div class="mw-heading mw-heading3"><h3 id="Kontraindikacije">Kontraindikacije</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Noradrenalin&veaction=edit&section=3" title="Uredi razdelek: Kontraindikacije" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Noradrenalin&action=edit&section=3" title="Urejanje izvorne kode razdelka: Kontraindikacije"><span>uredi kodo</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Pri sledečih stanjih se noradrenalin ne sme dajati ali pa je pri dajanju potrebna posebna pazljivost: </p> <ul><li><a href="/wiki/Zvi%C5%A1an_krvni_tlak" class="mw-redirect" title="Zvišan krvni tlak">zvišan krvni tlak</a>,</li> <li><a href="/w/index.php?title=Hipertiroizem&action=edit&redlink=1" class="new" title="Hipertiroizem (stran ne obstaja)">hipertiroizem</a>,</li> <li><a href="/wiki/Glavkom" title="Glavkom">glavkom</a>,</li> <li>povečana <a href="/wiki/Obse%C4%8Dnica" class="mw-redirect" title="Obsečnica">obsečnica</a> z zastajanjem <a href="/wiki/Se%C4%8D" title="Seč">seča</a>,</li> <li><a href="/w/index.php?title=Supraventrikularna_tahikardija&action=edit&redlink=1" class="new" title="Supraventrikularna tahikardija (stran ne obstaja)">supraventrikularna tahikardija</a>,</li> <li><a href="/w/index.php?title=Tahiaritmija&action=edit&redlink=1" class="new" title="Tahiaritmija (stran ne obstaja)">tahiaritmija</a>,</li> <li>težja <a href="/wiki/Ledvi%C4%8Dna_odpoved" class="mw-redirect" title="Ledvična odpoved">ledvična odpoved</a>,</li> <li>težje <a href="/wiki/Sr%C4%8Dno_popu%C5%A1%C4%8Danje" title="Srčno popuščanje">srčno popuščanje</a>,</li> <li>težja <a href="/w/index.php?title=Arterioskleroza&action=edit&redlink=1" class="new" title="Arterioskleroza (stran ne obstaja)">arterioskleroza</a>,</li> <li><a href="/wiki/Cor_pulmonale" class="mw-redirect" title="Cor pulmonale">cor pulmonale</a>.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Sklici">Sklici</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Noradrenalin&veaction=edit&section=4" title="Uredi razdelek: Sklici" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Noradrenalin&action=edit&section=4" title="Urejanje izvorne kode razdelka: Sklici"><span>uredi kodo</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist" style="list-style-type: decimal;"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-51-41-2-1"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-51-41-2_1-0">1,0</a></sup> <sup><a href="#cite_ref-51-41-2_1-1">1,1</a></sup> <sup><a href="#cite_ref-51-41-2_1-2">1,2</a></sup> <sup><a href="#cite_ref-51-41-2_1-3">1,3</a></sup> <sup><a href="#cite_ref-51-41-2_1-4">1,4</a></sup></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r5980307">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"»""«""›""‹"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free a,.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited a,.mw-parser-output .id-lock-registration a,.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription a,.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:#d33}.mw-parser-output .cs1-visible-error{color:#d33}.mw-parser-output .cs1-maint{display:none;color:#3a3;margin-left:0.3em}.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://scifinder-cas-org.proxy.library.nd.edu:9443/scifinder/view/scifinder/scifinderExplore.jsf">»51-41-2«</a>. <i>SciFinder</i>. 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