CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,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);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="390"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "pubs.acs.org",cType: 'managed',cRay: '92ac497fbf90fd00',cH: '6x8S9emWxbibMsS7sOyi0MiUP0MjEKza0pW_G2q8bhI-1743722327-1.2.1.1-Yg6dOjeUm80R1EyHtDhNN4DRr5gvfKBugMJwmJ9MD6W8nN3TtQY3AEDUlExRJSLJ',cUPMDTk: "\/doi\/abs\/10.1021\/ja01478a033?__cf_chl_tk=Ut4GOjy1TaVOK8_nHNnazTT73ykp8Iy_z9vPgZL3bl4-1743722327-1.0.1.1-WnIq5.ZC5p.Hhz28_ugDG0M9oBKaMY8qULdwmy.auQU",cFPWv: 'g',cITimeS: '1743722327',cTTimeMs: '1000',cMTimeMs: '390000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/doi\/abs\/10.1021\/ja01478a033?__cf_chl_f_tk=Ut4GOjy1TaVOK8_nHNnazTT73ykp8Iy_z9vPgZL3bl4-1743722327-1.0.1.1-WnIq5.ZC5p.Hhz28_ugDG0M9oBKaMY8qULdwmy.auQU",md: "UbOyFYUBDqde_DU9qsmoD38pgjUhX1vGfVn9CTjLV4k-1743722327-1.2.1.1-MiTp.Q107wm5PDFKFDPjs8kcCAgG8w7WVONoTviToE5nyNdmqcqt1taY7CftwsCydzfHC1fsm9TuVhUFKgOi9BD2hAhReLQhh1uAkkQo0Gomq.kzbUfyFCGSXbevhV2VnzgRg6rxxMjXlmRcRzrj4JivBROxkWJ9fWy0G7cSqn9tbji.hwp80UAVxA5nleBfkUHJ46B1llWnxe_NKpjIIbJha9dqAuySw67PFplu4T.QVsQow_1PcF3sc_XBUPJILI3ko0y8408rEwcsoc39Pp9otdJDZds9MOYDLQyESODFzlzZpFTT4bT0wK7q4NLrbU8EiD5kYBTt1yBXnLgSzdz3BRjVrnzDP9ZHGoIjLUNIfcbEYL6_o1kZQJYphB9eNYNVufWV8U4V..H53pLEmwH50F.XStEz2UgbBtZl8JLesEWKIYrLY9J7kcIRSLeRn8h_WFkC10GRxjK65dQlsijEAHcI2En6GxcNibn9tfTEdvKStVxKTDxSE2qaJPBS9LvJ0lj7a_Qep0qg2qs6qBYrBu792i0RIH0hRVvIhu1U02AfuNwfgXeLxlXU8fVF8PMba6dT7RYNJ8C29zPrcqykKRYSoYgHLc3vs2zMCtQwq25olmeAcNUybvvXpImnQshkxsKPL9RoXiWtJ.VoVz16qSICd7Zp.A4CqzBredN1SbX4vwdezC41SOXJCDLsNh2JmgcLg5oVIEDMrwEnRYfqts6aK5TODWr662aYo2LnXFqALQR19euajwHMNwFcab6EQ8b0XVtUXDRoa5s1YK1kGbKpncwh8GiIRM9APq2M9FFtjILDiatC9JXG6DfMnw8hxjwJ.w805vKjiMtr2rTKmIDzvAwOMrVg5cFRXfwOlWUZwZj.oE_EcMPiBLlMO6UoySLiloPVHEfY6X6EiU0gyfOT.KJNy1ba.QmLQlAfIRdriR5VsTSoK2AeuO_.Dw7v7tU2Q69G50rZcfxku2CiSFOqlIqNC70E58h.oCM4gXdco8mw5C6OjxR4rOoObtlEuVJYwml9DbUjQfWQprX06twDDmjrfDcgicaI_OeGuws67qdq.pA8Wgm6owFEPxjsxapfw1nsyJR4rduG8W8b5SmIPHwfAT6jktFJv6Mo_UniJby1v2LkxoDduf21JJUW50iRth94Ne4WAffAyj__s_v4cesA5dnAanqTexxH6MrY9nKDOirKHd0qceIXqTUG6RWE6lwwYJX4InuNC3fVfqv86qC6Dy2MPgKapzFj.VVX77I2d0auetaI4V_5eSC0S22O0J.rnm_E9ZjOUw",mdrd: "oSmPY6p2k.tdtR1lDq36ai3XI2wqLJ.SbauD5b4EIsw-1743722327-1.2.1.1-GJR5QR1wwW3mPHJvSbGAYNqICmRgy5bLP.yM1Eayhi7MRM94cDqNfJm0Juf3bI4YBJWMPW_CqyUrOXNUayvb4r1m.qPo.I.3cZx2fEF4ByAo4oBVqXoXpK_glLjm.hSwLMukpNvSfzqfdnMMYsVScq_bKx3DmtyBf7iJfVxyHfQs6_l0OnoIOzMiJOFsZp0jRLgkSXf0wqekOkMvV6woUm27PeIfpr6ZpQdhUTuTqqyYvBd85Va9WGJ4tVACflB2cGcQ0JsD7hVd1cxa0_P2LprHCCNs9OrRf2dw.tpcIFOMwRcZLZ6PrciMxJRQMepcY68gakJwdx1cmzJ8grV9GJGO8mcRAhGdI7_ZmfYZ3UtDPuiqcxuUam.qwTSxiFKR9apJbGVvO2dmVjrOyxPZuPuDMNhVg1J7_NPBLoG3QlvaycLR1xiG7oUk9cZrybmKveOl4FHzdZNfo1ox6OmdGJZ.fCyqD0dIqSMvNngVMB2TpWVWSXYd.Q2S8oi.pMBSaPJBg.Vy354Q1zQ7RwueTupi4yCNSu97w2AoaYgcUBMR8x0PCzwI7C.4oEQWy9GkHA3UWGWI3RU1sQdTDt.wW05OUKPZW4f3YrXnKpBToBBy4StXqSX5L9.nS_5l6aHRekNiq1S_tdl0KFlzRBK7jasgH.ByvZM8pVUF2BKmzihNkjh79fWBJXGIr_A2pidrupEZOFwydwh4iIjdBa4xKscreLEHO1CiEdIkHcCfXtw4uNMUt6NQ1fhuAYPuiWmrxEu0lM93X4tPHbQ6lZL2gJUNzvS9gYDReUDw4ypMkipvmaWO59jvn73wGJawT8QiTzOtT.rfFBNgrNf.DIv_Yx7FUB2ebnh16fBvHQVLDRnHk8lWXG3cpym8ABAHsG7QuHuGVDpv.FWJXQdU.uLwY5c7YJjczih0VK5M73wjk87mt9.Ci.k2ddDhK5OV1rqvukvp5XZRUenjDfa.rPAMMqGEOBGeOLQB7qAqax50FWLHr6VnkNbNr3TLkxBv97EcwRENcS_9ZqeLQkKBl8VB93Pr1bsyynrzSHCPcqwQVGWswgfDyoZ0vFedpUBoBrc3X3h_bLXRoQb0g1Av1zvtZbOZUVP5H90PBH0THRSrABSwrN2m7bAii3R_ji5xB.EqTAWbLBQ2hWw9v6v3Xzk7Xu5SBouUdaIcTKcazFVjsFxi4M6mWZfS8wnaveuKScbBrHdzp.XHWcoXBHRDFpBIbPdseZwKDCLHW3s3T5Seecf_Jiz9xoriGsKDkmp2GLeKa5qUw_sLp2JFj9FS4HfpZ9g4nZrzJskZxJTQr4BfWDjLcFXnUiqBnOvJI6Wab0EIpwOpwYsX8K9L9BR.I_zOn.hY8R_IwVCecBRT3Q_wFBRphMDPMae9kz.aWuofwKkoI0nxT3_gXY3KziAqNE.xabdThacZimdkFmFVJvdk9wn3KH.PVTngCSXrkKs1BUAvooZW8gTMNX3BGAJjABleYZSPiFV.ybtdxOgEy3UYAhPey9eLDFcxa4_t.0o4NqWLqM8LCqo4m0g.I4IrqSOjoUKrswI5hlLfWd_OxDQN4SO51x.2vvsL6npzaF3ZuVI3DymXgVkXlf7IfqjGRk.h5D8YE0kVKDMn7cblZvJF5MjV4ZBD4fIBZuvRPlJ3rYxzs_GokUWrsaLXflY.RZlglo741AvP87J9duxu8P_R77eMeD9Wj22unUZokbKqGxvKfZxsV1tbhSZKY958LCUpgIEBB2avA8g.bxnMIgPnIIv5QEkxc6RXatEICCswN9GU_3sBiObi.MlZA4szYXQQmJjLND3goqXtp0jNf5RJiGNE38.QYtFWus1BKihslILbz79pydLQt.nTjvZbf8cA6N2ya1_XumIHbhfFhk76X5gHmAxPQMdgtA8bZAZlXR.e5kAtpqAt.ln9jdBS9IIWgI0qDmV8hgoHaO6zvVYdtuH7wUnumevJNhANo2RfBwkYE72jNpeyrVtYZUIHi9Cy_UCgpZnVpx.CWHGIrqfSceV0jjOiY1qG2.qj8I3HrPbE"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/g/orchestrate/chl_page/v1?ray=92ac497fbf90fd00';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/doi\/abs\/10.1021\/ja01478a033?__cf_chl_rt_tk=Ut4GOjy1TaVOK8_nHNnazTT73ykp8Iy_z9vPgZL3bl4-1743722327-1.0.1.1-WnIq5.ZC5p.Hhz28_ugDG0M9oBKaMY8qULdwmy.auQU" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>