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cubic-bezier(.37,.74,.15,1);width:auto;z-index:2000}.TooltipD:after{bottom:-10px;color:var(--black);content:"";font-family:Frontiers-Iconography-Next!important;font-size:16px;height:16px;position:absolute;right:calc(50% - 8px);width:16px}.TooltipD--bottom:after{bottom:auto;top:-10px;transform:rotate(180deg)}.TooltipD--right:after{right:12px}.TooltipD--left:after{left:12px;right:auto}.TooltipD--side.TooltipD--left:after{bottom:calc(50% - 8px);left:auto;right:-10px;transform:rotate(-90deg)}.TooltipD--side.TooltipD--right:after{bottom:calc(50% - 8px);left:-10px;right:auto;transform:rotate(90deg)}.FloatingDirectiveElement{--floating-element-margin:40px;bottom:0;margin:0;opacity:0;position:fixed;right:var(--floating-element-margin);transition:opacity .48s cubic-bezier(.37,.74,.15,1),visibility .48s cubic-bezier(.37,.74,.15,1),bottom .48s cubic-bezier(.37,.74,.15,1);visibility:hidden;z-index:30}@media only screen and 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body a.Link.Link--maincolor:hover{background:initial}html body a.Link.Link--maincolor:hover span:before{content:none}html body .Spinner{display:flex;justify-content:center;width:var(--layout-col-12)}@media only screen and (max-width:1280px){html body .Spinner{width:var(--layout-col-14)}}@media only screen and (max-width:1024px){html body .Spinner{width:var(--layout-col-20)}}@media only screen and (max-width:768px){html body .Spinner{width:var(--layout-col-21)}}@media only screen and (max-width:563px){html body .Spinner{width:var(--layout-col-24)}}html body .Spinner__icon{fill:var(--maincolor80)}html body .Section__title{font-size:2rem;font-weight:500;line-height:2.75rem;margin-bottom:24px}@media only screen and (max-width:1280px){html body .Section__title{font-size:1.75rem;font-weight:500;line-height:2.4375rem}}@media only screen and (max-width:1024px){html body .Section__title{font-size:1.5rem;font-weight:500;line-height:2.0625rem}}@media only screen and (max-width:563px){html body .Section__title{font-size:1.25rem;font-weight:500;line-height:1.75rem}}</style> <style>:where(:not(html,iframe,canvas,img,svg,video,audio,svg *,symbol *)){all:unset;display:revert}*,:after,:before{box-sizing:border-box}html{-moz-text-size-adjust:none;-webkit-text-size-adjust:none;text-size-adjust:none}a,button{cursor:revert}menu,ol,summary,ul{list-style:none}img{max-block-size:100%;max-inline-size:100%}table{border-collapse:collapse}input,textarea{-webkit-user-select:auto}textarea{white-space:revert}meter{-webkit-appearance:revert;-moz-appearance:revert;appearance:revert}:where(pre){all:revert;box-sizing:border-box}::-moz-placeholder{color:unset}::placeholder{color:unset}:where([hidden]){display:none}:where([contenteditable]:not([contenteditable=false])){-moz-user-modify:read-write;-webkit-user-modify:read-write;-webkit-line-break:after-white-space;overflow-wrap:break-word;-webkit-user-select:auto}:where([draggable=true]){-webkit-user-drag:element}:where(dialog:modal){all:revert;box-sizing:border-box}::-webkit-details-marker{display:none}</style> <style>.ValidationMessage{display:flex;font-size:.875rem;font-weight:300;gap:4px;line-height:1.25rem;margin-top:4px}</style> <style>.DropDown{--color-value:#6b6b6b;--color-label:#6b6b6b;--color-background:#fff;--color-border:var(--grey40);list-style:none;margin-bottom:8px;position:relative}.DropDown.is-filter-error{text-align:left}.DropDown.is-filter-error .DropDown__titleContainer{--color-background:var(--red0);--color-border:var(--red40)}.DropDown.is-filter-error .DropDown__titleContainer .DropDown__title,.DropDown.is-filter-error .DropDown__titleContainer:after{--color-value:var(--red40)}.DropDown.is-disabled{opacity:1}.DropDown.is-disabled .DropDown__titleContainer{--color-value:var(--grey40);--color-border:var(--grey30)}.DropDown.is-disabled .DropDown__titleContainer:focus{box-shadow:none}.DropDown.is-disabled .DropDown__titleContainer:after{--color-value:var(--grey40);transform:none}.DropDown.is-readonly .DropDown__option{--color-value:var(--grey70);pointer-events:none}.DropDown__wrapper{line-height:30px;position:relative}.DropDown__titleContainer{background-color:var(--color-background);border:1px solid var(--color-border);border-radius:8px;box-sizing:border-box;cursor:pointer;font-size:1rem;font-weight:300;line-height:1.375rem;min-height:48px;padding:6px 16px;position:relative;text-align:left;transition:box-shadow .24s cubic-bezier(.37,.74,.15,1);width:100%}.DropDown__titleContainer--active:after{transform:rotate(180deg)}.DropDown__titleContainer--active,.DropDown__titleContainer:hover{border-color:var(--color-border);color:var(--color-value)}.DropDown__titleContainer--active:after,.DropDown__titleContainer:hover:after{color:#6b6b6b}.DropDown__titleContainer--active,.DropDown__titleContainer:focus{box-shadow:0 2px 4px #28282829,0 1px 10px #28282814;z-index:11}.DropDown__titleContainer--active .DropDown__title,.DropDown__titleContainer--hasValue 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var(--color-border);border-radius:8px;box-shadow:0 12px 17px #2828281f,0 5px 22px #28282814,0 7px 8px #2828280a;box-sizing:border-box;display:flex;display:none;flex-direction:column;left:0;overflow:hidden;pointer-events:none;position:absolute;top:calc(100% + 8px);width:100%;z-index:10}.DropDown__menuWrapper--open{display:block;opacity:1;pointer-events:all}.DropDown__menuWrapper--no-items{background-color:var(--white);border-bottom-style:none}@media only screen and (max-width:563px){.DropDown__menuWrapper{background-color:transparent;border:none;box-shadow:none;left:0!important;overflow:visible;position:fixed;top:0!important;z-index:1020}}.DropDown__menu{background-color:#fff;margin:0;max-height:190px;overflow-x:hidden;overflow-y:auto;padding:5px 0;z-index:1}.DropDown__menu::-webkit-scrollbar{-webkit-appearance:none;background:transparent;height:10px;width:10px}.DropDown__menu::-webkit-scrollbar-thumb{background-color:var(--grey40);border:3px solid 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24px;text-align:left}.DropDown+.Messaging{--color:#282828;color:var(--color);font-size:.625rem;font-weight:500;line-height:.875rem;margin-top:4px;padding-left:16px;position:relative;text-align:initial}.DropDown+.Messaging__error:before{color:var(--red50);content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;font-size:10px;font-weight:300;height:12px;left:0;line-height:10px;position:absolute;top:2px;width:12px}</style> <style>.Card{background-color:#fff;border-radius:8px;box-sizing:border-box;color:#282828;display:flex;overflow:hidden;transition:box-shadow .48s cubic-bezier(.37,.74,.15,1);width:100%}.Card:hover{box-shadow:0 0 17px #2828281f,0 0 22px #28282814,0 0 8px #2828280a}.Card__link{display:flex;flex-direction:column;width:100%}.Card__img{aspect-ratio:16/9;flex-shrink:0;margin:0;overflow:hidden;position:relative}.Card__body{box-sizing:border-box;display:flex;flex:1;flex-flow:column;padding:24px 32px}@media only screen and 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var(--size-icon)*.5);-webkit-font-smoothing:antialiased}.Button--disabled{opacity:.5;pointer-events:none}.Button--sky40{--color-button:var(--sky50);--color-button-hover:var(--sky70);--color-button-textFlat:var(--white);--color-button-textOutline:var(--sky50)}.Button--blue40,.Button--blue50{--color-button:var(--blue50);--color-button-hover:var(--blue70);--color-button-textFlat:var(--white);--color-button-textOutline:var(--blue50)}.Button--blue70{--color-button:var(--blue70);--color-button-hover:var(--blue80);--color-button-textFlat:var(--white);--color-button-textOutline:var(--blue70)}.Button--blue80{--color-button:var(--blue80);--color-button-hover:var(--blue90);--color-button-textFlat:var(--white);--color-button-textOutline:var(--blue80)}.Button--grey{--color-button:#6b6b6b;--color-button-hover:#545454;--color-button-textFlat:var(--white);--color-button-textOutline:#6b6b6b}.Button--grey70{--color-button:#545454;--color-button-hover:#282828;--color-button-textFlat:var(--white);--color-button-textOutline:#282828;border-color:#6b6b6b}.Button--grey80{--color-button:#545454;--color-button-hover:#282828;--color-button-textFlat:var(--white);--color-button-textOutline:#545454}.Button--maincolor{--color-button:var(--maincolor50);--color-button-hover:var(--maincolor70);--color-button-textFlat:var(--white);--color-button-textOutline:var(--maincolor50)}.Button--white{--color-button:var(--white);--color-button-hover:var(--grey10);--color-button-textFlat:#282828;--color-button-textOutline:var(--white)}.Button--small{--button-padding-horizontal:16px;--button-padding-vertical:5px;--padding-iconButton:24px;--size-icon:12px;font-size:.875rem;font-weight:700;line-height:1.25rem}.Button--medium{--button-padding-horizontal:24px;--button-padding-vertical:8px;--padding-iconButton:36px;font-size:1rem;font-weight:700;line-height:1.375rem}.Button--large{--button-padding-horizontal:32px;--button-padding-vertical:9px;--padding-iconButton:40px;font-size:1.125rem;font-weight:700;line-height:1.75rem}</style> <style>.RadioInputList{--color-value:#282828;--color-label:#545454;--color-background:transparent;--color-border:var(--grey40);--color-hover-border:var(--grey40);position:relative;text-align:left}.RadioInputList>span{display:flex;flex-flow:row wrap;transition:all 1s ease}@media only screen and (max-width:563px){.RadioInputList>span{flex-flow:column}}.RadioInputList__wrapper+.Messaging{--color:#282828;color:var(--color);font-size:.625rem;font-weight:500;line-height:.875rem;margin-top:0;padding-left:16px;position:relative;text-align:initial}.RadioInputList__wrapper+.Messaging__error:before{color:var(--red50);content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;font-size:10px;font-weight:300;height:12px;left:0;line-height:10px;position:absolute;top:2px;width:12px}.RadioInputList__wrapper .Button{font-size:1rem;font-weight:500;line-height:1.375rem;margin-top:16px}.RadioInputList__wrapper .Button--icon:after{transform:rotate(90deg)}.RadioInputList__item{width:50%}@media only screen and (max-width:563px){.RadioInputList__item{width:100%}}.RadioInputList__label,.RadioInputList__subLabel{color:#6b6b6b;font-size:.875rem;font-weight:300;line-height:1.25rem}.RadioInputList__subLabel{display:block}.RadioInputList__checkmark{border:1px solid var(--color-border);border-radius:50%;box-sizing:border-box;display:grid;height:24px;place-items:center;transition:border-color .25s cubic-bezier(.37,.74,.15,1),background-color .25s cubic-bezier(.37,.74,.15,1),box-shadow .25s cubic-bezier(.37,.74,.15,1);width:24px}.RadioInputList__checkmark:after{background:#fff;border-radius:50%;content:"";display:none;height:12px;width:12px}.RadioInputList__container{align-items:center;color:var(--color-label);cursor:pointer;display:flex;font-size:1rem;font-weight:300;gap:16px;line-height:1.375rem;margin-bottom:16px;position:relative;-webkit-user-select:none;-moz-user-select:none;user-select:none}.RadioInputList__container input{opacity:0;position:absolute}.RadioInputList__container input:checked~.RadioInputList__checkmark{--color-background:#282828;--color-border:#282828;border-width:6px}.RadioInputList__container input:checked~.RadioInputList__checkmark:after{display:block}.RadioInputList__container input:checked~.RadioInputList__label{color:#282828}.RadioInputList__container:hover .RadioInputList__checkmark{--color-border:var(--color-value);--color-background:var(--color-hover-border);box-shadow:0 0 1px 12px var(--color-hover-border)}.RadioInputList--disabled .RadioInputList__checkmark{background-color:var(--grey40)}.RadioInputList--disabled .RadioInputList__container{--color-label:var(--grey40);cursor:not-allowed}.RadioInputList--disabled .RadioInputList__container input{opacity:0;position:absolute}.RadioInputList--disabled .RadioInputList__container input~.RadioInputList__checkmark{--color-value:var(--grey40);--color-background:var(--grey40);--color-border:var(--grey40);box-shadow:none}.RadioInputList--disabled .RadioInputList__container input:checked~.RadioInputList__checkmark:after{background-color:var(--grey60);display:block}.RadioInputList__item.has-error .RadioInputList__checkmark,.RadioInputList__item.has-error input:checked~.RadioInputList__checkmark{--color-background:var(--red0);--color-border:var(--red50);box-shadow:none}.RadioInputList__item.has-error .RadioInputList__checkmark:after,.RadioInputList__item.has-error input:checked~.RadioInputList__checkmark:after{background-color:transparent}.RadioInputList__item.has-error .RadioInputList__container{--color-label:var(--red40)}.RadioInputList .fade-enter{opacity:0}.RadioInputList .fade-enter .fade-leave-active,.RadioInputList .fade-enter-active{transition:opacity .48s cubic-bezier(.37,.74,.15,1)}.FormContainer--blue .RadioInputList__item.has-error .RadioInputList__container:hover .RadioInputList__checkmark,.FormContainer--blue .RadioInputList__item.has-error input:checked~.RadioInputList__checkmark{box-shadow:none}.FormContainer--blue .RadioInputList__label{color:var(--white)!important}</style> <style>.SearchBar{align-items:center;background-color:#fff;border:1px solid var(--grey40);border-radius:8px;box-sizing:border-box;display:flex;height:80px;padding:0 16px;transition:box-shadow .48s cubic-bezier(.37,.74,.15,1);width:100%}@media only screen and (max-width:1280px){.SearchBar{height:56px}}@media only screen and (max-width:1024px){.SearchBar{height:48px}}.SearchBar--focused{box-shadow:0 1px 2px #2828281f,0 2px 1px #28282814,0 1px 3px #2828280a}.SearchBar__input{background-color:transparent;border:none;color:#282828;font-size:1rem;font-weight:300;height:100%;line-height:1.375rem;margin:0 16px;width:100%}.SearchBar__input::-webkit-input-placeholder{color:#6b6b6b;font-size:16px}.SearchBar__input:-moz-placeholder{color:#6b6b6b;font-size:16px}.SearchBar__input :-ms-input-placeholder{color:#6b6b6b;font-size:16px}@media only screen and (max-width:1024px){.SearchBar__input{font-size:.875rem;line-height:1.25rem;margin:0 8px}.SearchBar__input::-webkit-input-placeholder{color:#6b6b6b;font-size:14px}.SearchBar__input:-moz-placeholder{color:#6b6b6b;font-size:14px}.SearchBar__input :-ms-input-placeholder{color:#6b6b6b;font-size:14px}}.SearchBar i{--icon-size:32px;display:inline-flex;font-family:Frontiers-Iconography-Next!important;font-style:normal;-webkit-font-smoothing:antialiased;color:#545454;font-size:var(--icon-size);font-weight:300;height:var(--icon-size);line-height:var(--icon-size);width:var(--icon-size)}@media only screen and (max-width:1280px){.SearchBar i{--icon-size:24px}}.SearchBar__prependIcon:after{content:""}.SearchBar__prependIcon--loading:after{animation:rotate 2s linear infinite;content:""}.SearchBar__appendIcon{cursor:pointer}.SearchBar__appendIcon:after{content:"";font-size:16px}.SearchBar__hint{color:#6b6b6b;font-size:.875rem;font-weight:300;line-height:1.25rem;margin-left:24px;margin-top:8px;opacity:0;position:absolute;transition:opacity .4s cubic-bezier(.37,.74,.15,1);z-index:-1}@media only screen and (max-width:1024px){.SearchBar__hint{font-size:.75rem;line-height:1.0625rem;margin-top:6px}}.SearchBar__hint--show{opacity:1;z-index:1}</style> <style>.AlphabetDropDown.DropDown{display:inline-flex;height:40px;margin:0;width:auto}.AlphabetDropDown.DropDown.is-disabled .DropDown__titleContainer{color:var(--grey40)}.AlphabetDropDown .DropDown__title{display:none}.AlphabetDropDown .DropDown__selectedValue{display:inline-block!important;position:unset;width:unset}.AlphabetDropDown .DropDown__titleContainer{align-items:center;border-radius:96px;display:flex;height:100%;justify-content:space-between;min-height:unset;min-width:80px;width:auto}.AlphabetDropDown .DropDown__titleContainer:after{display:inline-block;position:unset}.AlphabetDropDown .DropDown__titleContainer--active,.AlphabetDropDown .DropDown__titleContainer:hover{color:#282828}.AlphabetDropDown .DropDown__titleContainer--active,.AlphabetDropDown .DropDown__titleContainer:focus{box-shadow:none}.AlphabetDropDown .DropDown__menuWrapper{min-width:280px;width:auto}@media only screen and (max-width:563px){.AlphabetDropDown .DropDown__menuWrapper{height:100%;width:100%}}.AlphabetDropDown .DropDown__menu{display:grid;grid-template-columns:repeat(5,1fr);grid-template-rows:repeat(6,1fr);grid-column-gap:16px;grid-row-gap:16px;height:auto;justify-items:center;max-height:-moz-fit-content;max-height:fit-content;padding:24px}.AlphabetDropDown .DropDown__option{border-radius:50%}.AlphabetDropDown .DropDown__option__button{align-items:center;border-radius:50%;color:#6b6b6b;display:flex;font-size:1rem;font-weight:500;height:48px;justify-content:center;line-height:1.375rem;padding:0;width:48px}.AlphabetDropDown .DropDown__option__button:hover{background-color:#f7f7f7}.AlphabetDropDown .DropDown__option--arrow-active.is-disabled{background-color:#f0f0f0}.AlphabetDropDown .DropDown__option--active .DropDown__option__button,.AlphabetDropDown .DropDown__option--active .DropDown__option__button:hover{background-color:#282828;color:var(--white)}.AlphabetDropDown .DropDown__option--active .DropDown__option__button:before{content:""}.AlphabetDropDown--selected .DropDown__titleContainer{background-color:#282828;border:none;color:var(--white)}.AlphabetDropDown--selected .DropDown__titleContainer:after,.AlphabetDropDown--selected .DropDown__titleContainer:hover,.AlphabetDropDown--selected .DropDown__titleContainer:hover:after{color:var(--white)}</style> <style>.Accordion__item{background:#fff;border-top:1px solid var(--grey10);box-shadow:0 2px 5px #0000001a}.Accordion__item,.Accordion__item--open{transition:margin .48s cubic-bezier(.37,.74,.15,1)}.Accordion__item--open{border-top:none;margin:16px 0}.Accordion__item--open .Accordion__headline{border-bottom:1px solid var(--grey10)}.Accordion__item--open+.Accordion__item,.Accordion__item:first-child{border-top:none}.Accordion__item:first-child.Accordion__item--open{margin-top:0}.Accordion__headline{align-items:center;border-color:transparent;cursor:pointer;display:flex;height:64px;justify-content:space-between;transition:border .48s cubic-bezier(.37,.74,.15,1);width:100%}.Accordion__title{color:#282828;font-size:1rem;font-weight:500;line-height:1.375rem;margin-top:2px;padding-left:24px}.Accordion__space{flex:1 0 auto}.Accordion__number{color:var(--grey50);font-size:1.25rem;font-weight:300;line-height:1.75rem;margin-top:-2px;padding-left:24px;width:64px}.Accordion__number sup{font-size:13px}.Accordion__arrow{height:16px;margin:0 16px;position:relative;width:16px}.Accordion__arrow:after{color:#6b6b6b;content:"";font-family:Frontiers-Iconography-Next!important;font-size:16px;font-weight:300!important;line-height:16px;-webkit-font-smoothing:antialiased;left:0;position:absolute;top:0;transition:transform .48s cubic-bezier(.37,.74,.15,1)}.Accordion__arrow--open:after{transform:rotate(180deg)}.Accordion__content{overflow:hidden}.Accordion__content>*{padding:24px}</style> <style>.Input{--color-value:#282828;--color-label:#6b6b6b;--color-background:#fff;--color-border:var(--grey40);position:relative;text-align:left}.Input__field{background-color:var(--color-background);border:1px solid var(--color-border);border-radius:8px;box-sizing:border-box;color:var(--color-value);font-size:1rem;font-weight:300;line-height:1.375rem;padding:18px 16px 6px;width:100%}.Input__field:focus{box-shadow:0 1px 2px #2828281f,0 2px 1px #28282814,0 1px 3px #2828280a}.Input__field--WithShowClearIcon{padding-right:36px}.Input__labelWrapper{box-sizing:content-box;height:100%;left:16px;overflow:hidden;pointer-events:none;position:absolute;width:100%}.Input__label{color:var(--color-label);display:inline-block;font-size:1rem;font-weight:300;line-height:1.375rem;position:absolute;top:13px;transform-origin:0 0;transition:transform .4s cubic-bezier(.25,.8,.25,1);z-index:5}.Input--enabled .Input__label{transform:translateY(-8px) scale(.75)}.Input--disabled{--color-value:var(--grey40);--color-border:var(--grey30);--color-label:var(--grey40)}.Input.has-error .Input__field{--color-background:var(--red0);--color-border:var(--red50)}.Input.has-error .Input__label{--color-label:var(--red40)}.Input+.Messaging{--color:#282828;color:var(--color);font-size:.625rem;font-weight:500;line-height:.875rem;margin-top:4px;padding-left:16px;position:relative;text-align:initial}.Input+.Messaging__error:before{color:var(--red50);content:"";font-size:10px;font-weight:300;height:12px;left:0;line-height:10px;top:2px;width:12px}.Input+.Messaging__error:before,.Input__appendIcon{font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;position:absolute}.Input__appendIcon{color:#545454;cursor:pointer;display:inline-flex;right:16px;top:21px}.Input__appendIcon:after{content:"";font-size:16px}@media only screen and (max-width:1280px){.Input__appendIcon:after{font-size:20px}}</style> <style>.DatePicker{margin-bottom:6px;position:relative;width:240px}.DatePicker.is-filter-error .DatePicker__titleContainer{border-color:var(--red50);color:var(--red50)}.DatePicker.is-filter-error .DatePicker__titleContainer:after{color:var(--red50)}.DatePicker.is-disabled{opacity:1}.DatePicker.is-disabled .DatePicker__titleContainer{background:var(--grey5);border-color:var(--grey40);color:var(--grey50)}.DatePicker.is-disabled .DatePicker__titleContainer:after{color:var(--grey50)}.DatePicker__titleContainer{background:var(--white);border:1px solid var(--grey40);box-sizing:border-box;color:var(--grey80);cursor:pointer;display:flex;font-size:13px;font-weight:500;height:36px;line-height:36px;padding:0 28px 0 8px;position:relative;text-align:left;transition:box-shadow .24s cubic-bezier(.37,.74,.15,1);width:100%}.DatePicker__titleContainer--active,.DatePicker__titleContainer:hover{border-color:var(--grey50);color:var(--grey50)}.DatePicker__titleContainer--active:after,.DatePicker__titleContainer:hover:after{color:var(--grey70)}.DatePicker__titleContainer--active{z-index:11}.DatePicker__titleContainer--active:after{transform:rotate(180deg)}.DatePicker__titleContainer .DatePicker__selectedValue{display:none}.DatePicker__titleContainer.is-filtered{color:var(--grey50)}.DatePicker__titleContainer.is-filtered .DatePicker__emptyValue{display:none}.DatePicker__titleContainer.is-filtered .DatePicker__selectedValue{display:inline-block}.DatePicker__titleContainer:after{color:var(--grey80);content:"";font-family:Frontiers-Iconography-Next!important;font-size:12px;font-weight:300!important;line-height:12px;-webkit-font-smoothing:antialiased;position:absolute;right:8px;top:11px}.DatePicker__title{padding-right:5px;position:relative;white-space:nowrap}.DatePicker__title:after{content:":"}.DatePicker__title:empty{display:none}.DatePicker__emptyValue,.DatePicker__selectedValue{overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.DatePicker__header{align-items:center;border-bottom:1px solid var(--grey40);display:flex;justify-content:space-between}.DatePicker__header__nextMonth,.DatePicker__header__prevMonth{cursor:pointer}.DatePicker__header__nextMonth:before,.DatePicker__header__prevMonth:before{color:var(--grey80);font-family:Frontiers-Iconography-Next!important;font-size:16px;font-weight:300!important;line-height:16px;-webkit-font-smoothing:antialiased;display:block;text-align:center}.DatePicker__header__prevMonth:before{content:""}.DatePicker__header__prevMonth--responsive{display:none}@media only screen and (max-width:563px){.DatePicker__header__prevMonth--responsive{display:block}}.DatePicker__header__nextMonth:before{content:""}.DatePicker__header__inputs{display:flex;flex:1 0 auto}.DatePicker__header__inputs input[type=number]::-webkit-inner-spin-button,.DatePicker__header__inputs input[type=number]::-webkit-outer-spin-button{-webkit-appearance:button}.DatePicker__header__inputs input[type=number]{-moz-appearance:button}.DatePicker__header__inputs__year{border:0;border-style:solid;box-sizing:border-box;padding-left:5px;width:76px}.DatePicker__header__inputs__year:hover{border-color:var(--grey20)}.DatePicker__header__inputs__year::-webkit-textfield-decoration-container{height:100%}.DatePicker__header__inputs .DropDown{border-right:1px solid var(--grey40);margin-bottom:0;width:94px}.DatePicker__header__inputs .DropDown__menu{max-height:176px}.DatePicker__header__inputs .DropDown__titleContainer{border:none;height:32px;line-height:32px}.DatePicker__header__inputs .DropDown__titleContainer:hover{border-color:var(--grey20)}.DatePicker__header__inputs .DropDown__titleContainer:after{top:10px}.DatePicker__header__inputs .DropDown__menuWrapper{left:-1px;top:calc(100% + 1px);width:calc(100% + 2px)}@media only screen and (max-width:1024px){.DatePicker__header__inputs .DropDown__menuWrapper{border:1px solid var(--grey40);box-shadow:0 2px 5px #0003,0 12px 50px #0003;left:0!important;max-height:200px;position:absolute;top:calc(100% + 1px);transform:none;width:100%}.DatePicker__header__inputs .DropDown__overlay,.DatePicker__header__inputs .DropDown__titleMobile{display:none}}.DatePicker__month{display:flex;flex-wrap:wrap;justify-content:center;padding-top:8px;text-align:center;width:224px}@media only screen and (max-width:1024px){.DatePicker__month{width:252px}}@media only screen and (max-width:563px){.DatePicker__month{width:100%}}.DatePicker__month__date,.DatePicker__month__day{align-self:center;border:1px solid transparent;box-sizing:border-box;height:32px;width:32px}@media only screen and (max-width:1024px){.DatePicker__month__date,.DatePicker__month__day{height:36px;width:36px}}@media only screen and (max-width:563px){.DatePicker__month__date,.DatePicker__month__day{height:46px;width:46px}}.DatePicker__month__day{color:var(--black);cursor:default;font-size:11px;font-weight:500;line-height:24px}.DatePicker__month__date{border-radius:50%;color:var(--grey40);cursor:pointer;font-size:.875rem;font-weight:500;line-height:1.25rem;opacity:0;pointer-events:none;position:relative}@media only screen and (max-width:1024px){.DatePicker__month__date{font-size:.75rem;font-weight:500;line-height:1.0625rem}}.DatePicker__month__date--current-date,.DatePicker__month__date--current-month{color:var(--grey70);opacity:1;pointer-events:all}.DatePicker__month__date:hover{background-color:var(--grey10);border:1px solid var(--grey10);transition-duration:.2s;transition-property:background-color,border-color;transition-timing-function:ease-in-out}.DatePicker__month__date--selected-date{background-color:var(--grey80);color:#fff;cursor:default}.DatePicker__month__date--selected-date:hover{background-color:var(--grey80);border-color:var(--grey80)}.DatePicker__month__date--notAllowed{color:var(--grey40);cursor:not-allowed}.DatePicker__month__date--notAllowed:hover{background-color:transparent;border-color:transparent;cursor:not-allowed}.DatePicker__menuWrapper{background-color:var(--white);border:1px solid var(--grey50);box-sizing:border-box;display:flex;flex-direction:column;width:240px}.DatePicker__menu{background-color:var(--white);margin:0;padding:0;position:relative;z-index:1}@media only screen and (max-width:563px){.DatePicker__menu:first-child{display:none}}.DatePicker__menuWrapper{display:none;left:0;pointer-events:none;position:absolute;top:calc(100% - 1px);z-index:10}.DatePicker__menuWrapper--open{display:block;opacity:1;pointer-events:all}@media only screen and (max-width:1024px){.DatePicker__menuWrapper{background-color:transparent;border:none;box-shadow:none;left:50%!important;max-height:90vh;max-width:none;overflow:visible;position:fixed;right:auto!important;top:50%;transform:translate(-50%,-50%);width:240px;z-index:1020}}.DatePicker__overlay{display:none;pointer-events:none}@media only screen and (max-width:1024px){.DatePicker__overlay{background-color:#000000b3;display:block;height:100%;left:0;pointer-events:all;position:fixed;top:0;width:100%;z-index:1000}}.DatePicker__titleMobile{background:transparent;color:#fff;display:none;margin:0 0 5px;padding:10px 10px 10px 0;text-align:left}@media only screen and (max-width:1024px){.DatePicker__titleMobile{display:block}}.DatePicker__monthName{color:var(--black);font-size:1rem;font-weight:500;line-height:1.375rem;text-align:center;width:100%}.DatePicker__month__header{display:flex}.is-hidden{display:none}.DateRangePicker{position:relative}@media only screen and (max-width:563px){.DateRangePicker{padding:0}}.DateRangePicker__wrapper{background-color:var(--white);border:1px solid var(--grey40);border-radius:8px;box-shadow:0 12px 17px #2828281f,0 5px 22px #28282814,0 7px 8px #2828280a;margin-top:4px;max-width:890px;padding:24px;position:absolute;z-index:1}@media only screen and (max-width:563px){.DateRangePicker__wrapper{border:none;box-shadow:none;height:auto;left:0;margin:0;max-width:100%;padding:0;position:fixed;top:0;width:100%;z-index:99}}.DateRangePicker__scrollWrapper{-moz-column-gap:56px;column-gap:56px;display:flex;flex-flow:row wrap}@media only screen and (max-width:1024px){.DateRangePicker__scrollWrapper{flex-flow:column}}@media only 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(max-width:1441px){.Footer__sections{flex-wrap:wrap;padding-bottom:0}}@media only screen and (max-width:1024px){.Footer__sections{padding:0 16px}}.Footer__socialLinks{color:#282828;font-size:1rem;font-weight:300;line-height:1.375rem;min-width:192px}@media only screen and (max-width:1441px){.Footer__socialLinks{border-top:1px solid var(--grey30);padding:56px 0;width:100%}}@media only screen and (max-width:1024px){.Footer__socialLinks{border-top:none;padding-bottom:48px;text-align:center}}.Footer__socialLinks__title{margin-bottom:16px}.Footer__socialLinks .Link__wrapper:not(:last-of-type){margin-right:32px}.Footer__socialLinks .Link__wrapper .Link--icon{--size-icon:24px}.Footer__socialLinks .Link__wrapper .Link--icon:after{margin-left:0;margin-right:0}.Footer__copyright{border-top:1px solid var(--grey30);display:flex;flex-direction:row;font-size:1rem;font-weight:300;line-height:1.375rem;padding:56px 0;width:100%}@media only screen and (max-width:1441px){.Footer__copyright{margin-left:0}}@media only screen and (max-width:1024px){.Footer__copyright{border-top:1px solid var(--grey20);flex-direction:column;margin:0 auto;padding:48px 0 64px;text-align:center;width:400px}.Footer__copyright div:first-child{margin-bottom:13px}.Footer__copyright div:first-child+div{display:flex;justify-content:center}.Footer__copyright div:first-child+div span{color:var(--grey40);margin:0 8px}}@media only screen and (max-width:740px){.Footer__copyright{width:311px}.Footer__copyright div:first-child{align-self:center;width:215px}}.Footer__copyright span:first-child{margin:0 32px 0 0}@media only screen and (max-width:740px){.Footer__copyright span:first-child{margin:0}}.Footer .Accordion__arrow:after{color:#282828}.Footer .Accordion__content{background-color:var(--grey5)}.Footer .Accordion__content li{margin-bottom:16px}.Footer .Accordion__content li:last-child{margin-bottom:0}.Footer .Accordion__content a{color:#6b6b6b;font-size:1rem;font-weight:300;line-height:1.375rem}@media only screen and (max-width:1024px){.Footer .Accordion__item{border-bottom:1px solid var(--grey30);border-top:none;box-shadow:none}.Footer .Accordion__item .Accordion__headline{border-color:var(--grey30);box-sizing:content-box;height:22px;padding:32px 0;transition:padding .48s cubic-bezier(.37,.74,.15,1)}.Footer .Accordion__item:first-child .Accordion__headline{padding-top:32px}}.Footer .Accordion__item--open{margin:0}.Footer .Accordion__item--open .Accordion__headline{height:22px}@media only screen and (min-width:1025px){.Footer .Accordion{display:flex;width:100%}.Footer .Accordion__item{background:none;border-top:none;box-shadow:none;flex:1;width:100%}.Footer .Accordion__item:first-child .Accordion__content>ul,.Footer .Accordion__item:first-child .Accordion__title{padding-left:0}.Footer .Accordion__item .Accordion__content>ul{padding-bottom:56px}.Footer .Accordion__item--open{margin:0}.Footer .Accordion__item--open .Accordion__headline{border-bottom:none}.Footer .Accordion__headline{height:auto;pointer-events:none}.Footer .Accordion__headline:focus-visible{outline:none}.Footer .Accordion__arrow{display:none}.Footer .Accordion__content{background-color:#fff;height:auto!important;overflow:visible}.Footer .Accordion__content--fadeOut{opacity:1!important}}@media only screen and (max-width:1441px){.Footer .Accordion{width:100%}}</style> <style>.FrontiersVideo__container{aspect-ratio:var(--7b3d0757);position:relative;width:100%}.FrontiersVideo__container--contentful{aspect-ratio:auto}.FrontiersVideo__video{height:100%;left:0;position:absolute;top:0;width:100%}.FrontiersVideo__video--contentful{height:auto;position:relative}.FrontiersVideo__caption{margin-top:8px}</style> <style>.QuickFilters{box-sizing:border-box;display:flex;position:relative;width:100%}@media only screen and (max-width:1024px){.QuickFilters{overflow-x:auto;overflow-y:hidden}.QuickFilters::-webkit-scrollbar{display:none}@-moz-document url-prefix(){.QuickFilters{scrollbar-width:none}}}.QuickFilters__item{color:#6b6b6b;cursor:pointer;flex:0 0 auto;font-size:1rem;font-weight:300;line-height:1.375rem;margin:0 12px;padding:16px 0 8px;position:relative;text-align:left}.QuickFilters__item:first-child{margin-left:0}.QuickFilters__item span{font-weight:700;margin-right:2px}.QuickFilters__item--active{color:#282828;font-weight:500}.QuickFilters__item--active:after{background-color:#282828;bottom:1px;content:"";height:2px;left:0;position:absolute;width:100%}.QuickFilters__item--active.QuickFilters__more:after{display:none}.QuickFilters__item--active.QuickFilters__more .QuickFilters__more__trigger__text{font-weight:500}.QuickFilters__item--active.QuickFilters__more .QuickFilters__more__trigger__text:after{background-color:#282828;bottom:0;content:"";height:2px;left:0;position:absolute;width:100%}@media only screen and (max-width:1024px){.QuickFilters__item{font-size:.875rem;line-height:1.25rem}}.QuickFilters__more{padding-bottom:0;position:relative;width:210px}.QuickFilters__more__trigger{color:inherit;display:flex;font-weight:300;line-height:inherit;padding:0;position:relative;width:auto}.QuickFilters__more__trigger__text{max-width:200px;overflow:hidden;padding-bottom:8px;position:relative;text-overflow:ellipsis;white-space:nowrap}.QuickFilters__more__trigger__icon{margin-left:6px;position:relative;top:2px}.QuickFilters__more__trigger__icon:before{color:#6b6b6b;content:"";font-family:Frontiers-Iconography-Next!important;font-size:14px;font-weight:300!important;line-height:14px;-webkit-font-smoothing:antialiased}.QuickFilters__more__list{background-color:#fff;border:1px solid var(--grey60);border-radius:8px;box-shadow:0 4px 5px #2828281f,0 1px 10px #28282814,0 2px 4px #28282829;max-height:540px;max-width:360px;overflow:hidden;overflow-y:auto;position:absolute;top:calc(100% + 4px);z-index:102}.QuickFilters__more__list::-webkit-scrollbar{-webkit-appearance:none;background:transparent;height:10px;width:10px}.QuickFilters__more__list::-webkit-scrollbar-thumb{background-color:#2828283d;border:3px solid var(--white);border-radius:8px;-webkit-box-shadow:0 0 1px hsla(0,0%,100%,.5)}@-moz-document url-prefix(){.QuickFilters__more__list{scrollbar-width:thin}}.QuickFilters__more__list .QuickFilters__item{color:#6b6b6b;margin:0;overflow:hidden;padding:16px 28px 16px 40px;text-overflow:ellipsis;white-space:nowrap;width:100%}.QuickFilters__more__list .QuickFilters__item:hover{background-color:#f7f7f7;color:#282828;cursor:pointer}.QuickFilters__more__list .QuickFilters__item--active{position:relative}.QuickFilters__more__list .QuickFilters__item--active:after{display:none}.QuickFilters__more__list .QuickFilters__item--active:before{color:var(--black);content:"";font-family:Frontiers-Iconography-Next!important;font-size:14px;font-weight:300!important;line-height:14px;-webkit-font-smoothing:antialiased;left:16px;position:absolute;top:50%;transform:translateY(-50%)}</style> <style>.TagCloud{align-items:top;display:flex;flex-wrap:wrap;justify-content:left;margin:0 -4px;overflow:hidden}.TagCloud__tag{background:var(--white);border:1px solid var(--grey40);border-radius:96px;color:#545454;display:inline-block;font-size:.875rem;font-weight:300;line-height:1.25rem;margin:4px;max-width:100%;overflow:hidden;padding:4px 12px;text-align:center;text-overflow:ellipsis;white-space:nowrap}@media only screen and (max-width:1024px){.TagCloud__tag{font-size:.875rem;line-height:1.25rem;padding:4px 16px}}.TagCloud__tag:hover{background:var(--grey20);border:1px solid var(--grey60);color:#282828}</style> <style>.Pagination{margin:20px auto;width:100%}.Pagination--disabled{opacity:.5;pointer-events:none}.Pagination__wrapper{align-items:center;display:flex;gap:12px;justify-content:center}@media only screen and (max-width:563px){.Pagination__wrapper{gap:4px}}.Pagination__btnPage{border-radius:50%;color:var(--grey70);display:grid;flex-shrink:0;font-size:.875rem;font-weight:500;height:40px;line-height:1.25rem;place-items:center;text-align:center;width:40px}@media only screen and (max-width:1024px){.Pagination__btnPage{font-size:.75rem;font-weight:500;height:32px;line-height:1.0625rem;width:32px}}.Pagination__btnPage--isActive{background:var(--grey30)}.Pagination__btn{align-items:center;color:var(--grey80);display:flex;font-size:.875rem;font-weight:500;height:40px;line-height:1.25rem;position:relative;width:auto}.Pagination__btn--prev span{margin-right:12px}.Pagination__btn--next span{margin-left:12px}.Pagination__btn:disabled{color:var(--grey40);pointer-events:none}.Pagination__btn:disabled 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<style>.Ibar__dropdown{margin-left:var(--ibar-margin-between)}.Ibar__dropdown--aboutUs .Ibar__dropdown__trigger--open:before{bottom:-20px}.Ibar__dropdown__trigger{color:var(--ibar-color);font-size:.875rem;font-weight:500;line-height:1.25rem;position:relative;text-align:right;white-space:nowrap}.Ibar__dropdown__trigger:after{content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;display:inline-block;font-size:12px;font-weight:300;margin-left:8px;transition:transform .3s cubic-bezier(.37,.74,.15,1)}.Ibar__dropdown__trigger:before{background:var(--ibar-color-hover);bottom:-16px;content:"";height:2px;left:0;position:absolute;transform:scale(0);transition:transform .3s cubic-bezier(.37,.74,.15,1);width:100%}@media only screen and (max-width:1024px){.Ibar__dropdown__trigger:before{display:none}}.Ibar__dropdown__trigger--open,.Ibar__dropdown__trigger:hover,.Ibar__dropdown__trigger:hover:after{color:var(--ibar-color-hover)}@media only screen and 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cubic-bezier(.37,.74,.15,1);width:100%;z-index:-1}.Ibar__dropdown__menu::-webkit-scrollbar{-webkit-appearance:none;background:transparent;height:8px;width:8px}.Ibar__dropdown__menu::-webkit-scrollbar-thumb{background-color:var(--grey30);border:2px solid var(--white);border-radius:6px;-webkit-box-shadow:0 0 1px hsla(0,0%,100%,.5)}@-moz-document url-prefix(){.Ibar__dropdown__menu{scrollbar-width:thin}}@media only screen and (min-width:1921px){.Ibar__dropdown__menu{padding-left:calc(50vw - var(--layout-col-12) - var(--layout-gap)*1);padding-right:calc(50vw - var(--layout-col-12) - var(--layout-gap)*1)}}@media only screen and (max-width:1441px){.Ibar__dropdown__menu{padding:48px 128px 72px}}@media only screen and (max-width:1280px){.Ibar__dropdown__menu{padding:48px 128px 72px 96px}}@media only screen and (max-width:1024px){.Ibar__dropdown__menu{overflow:hidden}}.Ibar__dropdown__menu--visible{opacity:1;pointer-events:all;top:100%;transition:opacity .28s cubic-bezier(.37,.74,.15,1) .1s,top 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(max-width:563px){.Ibar__dropdown__sections{padding-top:40px}}.Ibar__dropdown__sections__item{color:#6b6b6b;font-size:.875rem;font-weight:500;line-height:1.25rem;margin-bottom:24px}.Ibar__dropdown__sections__item--active,.Ibar__dropdown__sections__item:hover{color:#282828}.Ibar__dropdown__about{display:flex}@media only screen and (max-width:563px){.Ibar__dropdown__about{padding-top:40px}}.Ibar__dropdown__about__block{box-sizing:border-box;flex-grow:1;max-width:33%}.Ibar__dropdown__about__block:last-child{padding-right:0}@media only screen and (max-width:1441px){.Ibar__dropdown__about__block{max-width:50%}}@media only screen and (max-width:1280px){.Ibar__dropdown__about__block{flex-grow:0;padding-right:80px}}@media only screen and 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cubic-bezier(.37,.74,.15,1),padding .3s cubic-bezier(.37,.74,.15,1),box-shadow .3s cubic-bezier(.37,.74,.15,1);width:0}.Ibar__menu .IbarOffice__dropdown>*{opacity:0}@media only screen and (max-width:768px){.Ibar__menu .IbarOffice__dropdown{left:calc(var(--layout-col-7) - 2px + var(--layout-gap)*2)}}@media only screen and (max-width:563px){.Ibar__menu .IbarOffice__dropdown{left:-100%;transition:none}}.Ibar__menu .IbarOffice__dropdown--visible{box-shadow:30px 0 32px #2828281f,12px 0 46px #28282814,11px 0 15px #28282829;padding:40px 32px;transition:width .3s cubic-bezier(.37,.74,.15,1),padding .3s cubic-bezier(.37,.74,.15,1),box-shadow .3s cubic-bezier(.37,.74,.15,1);width:calc(var(--layout-col-8) + var(--layout-gap))}.Ibar__menu .IbarOffice__dropdown--visible>*{opacity:1;transition:opacity .2s ease-in-out .15s}@media only screen and (max-width:563px){.Ibar__menu .IbarOffice__dropdown--visible>*{transition:none}}@media only screen and (max-width:768px){.Ibar__menu .IbarOffice__dropdown--visible{width:calc(var(--layout-col-7) + var(--layout-gap))}}@media only screen and (max-width:563px){.Ibar__menu .IbarOffice__dropdown--visible{box-shadow:none;left:0;padding:0 16px 16px;transition:none;width:100%;z-index:40}}.Ibar__menu .IbarOffice__dropdown::-webkit-scrollbar{-webkit-appearance:none;background:transparent;height:10px;width:10px}.Ibar__menu .IbarOffice__dropdown::-webkit-scrollbar-thumb{background-color:#28282829;border:3px solid var(--grey20);border-radius:5px;-webkit-box-shadow:0 0 1px hsla(0,0%,100%,.5)}@-moz-document url-prefix(){.Ibar__menu .IbarOffice__dropdown{scrollbar-width:thin}}.Ibar__menu .IbarOffice__dropdown__trigger{display:block;font-size:1rem;line-height:1.375rem;margin-left:0;padding:24px 0 24px 16px}.Ibar__menu .IbarOffice__dropdown__trigger:after{content:"";margin-left:16px}.Ibar__menu .IbarOffice__dropdown__trigger:before{line-height:20px;margin-right:8px}.Ibar__menu .IbarOffice__dropdown__trigger--open{color:#282828;font-weight:700}.Ibar__menu .IbarOffice__dropdown__trigger--open:after{transform:none}.Ibar__menu .IbarOffice__dropdown__item button{color:#282828;font-size:1rem;font-weight:700;line-height:1.375rem;margin-bottom:24px;padding:0 8px 8px 0;position:relative}.Ibar__menu .IbarOffice__dropdown__item button:after{background:var(--grey80);border-radius:2px;bottom:0;content:"";height:2px;left:0;position:absolute;width:48px}.Ibar__menu .IbarOffice__dropdown__item:last-child .IbarOffice__dropdown__subitemsList{border-bottom:none}.Ibar__menu .IbarOffice__dropdown__subitemsList{border-bottom:1px solid var(--grey40);margin-bottom:40px;max-height:none;padding-bottom:24px;position:inherit}.Ibar__menu .IbarOffice__dropdown__subitemsList button{display:none}.Ibar__menu .IbarOffice__dropdown__subitem a{padding:16px 0}.Ibar__userArea{height:var(--avatar-size);width:var(--avatar-size);--avatar-size:32px;margin-left:var(--ibar-margin-between)}@media only screen and (max-width:1280px){.Ibar__userArea{--avatar-size:32px}}@media only screen and (max-width:768px){.Ibar__userArea{--avatar-size:24px}}.Ibar__userLogged{display:grid;margin-left:var(--ibar-margin-between);place-items:center;position:relative}@media only screen and (max-width:563px){.Ibar__userLogged{position:unset}}.Ibar__userLogged>button{display:flex}.Ibar__userLogged__image{overflow:hidden}@media only screen and (max-width:1280px){.Ibar__userLogged__image .Avatar{--avatar-size:32px;--avatar-font-size:16px;--avatar-border-size:1px}}@media only screen and (max-width:768px){.Ibar__userLogged__image .Avatar{--avatar-size:24px;--avatar-font-size:14px;--avatar-border-size:1px}}.Ibar__user{background-color:#fff;border-radius:8px;box-shadow:0 12px 17px #2828281f,0 5px 22px #28282814,0 7px 8px #2828280a;color:var(--ibar-color-2);font-size:.875rem;font-weight:300;line-height:1.25rem;margin-top:4px;min-width:358px;overflow:auto;position:absolute;right:0;top:100%}@media only screen and (max-width:1024px){.Ibar__user{min-width:236px}}@media only screen and (max-width:563px){.Ibar__user{border:none;border-radius:0;height:100%;left:0;margin:0;position:fixed;top:0;width:100vw;z-index:3}}.Ibar__user__dropdown{padding:32px;text-align:center}@media only screen and (max-width:1024px){.Ibar__user__dropdown{padding:24px}}.Ibar__user__avatar{align-items:center;display:flex;justify-content:center;margin-bottom:12px}.Ibar__user__avatar .Avatar{--avatar-size:80px;--avatar-font-size:32px;--avatar-border-size:1px}.Ibar__user__list{color:#545454;padding:16px 0}.Ibar__user__list li{color:#6b6b6b;display:flex;font-size:.875rem;font-weight:500;line-height:1.25rem;width:100%}.Ibar__user__list li a{padding:16px 32px;width:100%}@media only screen and (max-width:1024px){.Ibar__user__list li a{padding:16px 24px}}@media only screen and (max-width:563px){.Ibar__user__list li a{text-align:center;width:100%}}.Ibar__user__list li:hover{background-color:#f7f7f7;color:#282828;cursor:pointer}.Ibar__user__separator{background-color:var(--grey30);height:1px;margin:0 32px}@media only screen and (max-width:1024px){.Ibar__user__separator{margin:0 24px}}.Ibar__user__name{color:#282828;font-size:1.125rem;font-weight:500;line-height:1.75rem;word-break:break-word}.Ibar__user__email{color:#6b6b6b;word-break:break-word}.Ibar__user__close{background-color:#f7f7f7;border-radius:50%;bottom:32px;box-shadow:0 0 11.3994px #0000001a;cursor:pointer;display:none;height:48px;left:calc(50% - 24px);position:absolute;width:48px}@media only screen and (max-width:563px){.Ibar__user__close{display:block}}.Ibar__user__close:before{content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;align-items:center;color:#282828;display:flex;font-size:16px;height:48px;justify-content:center;line-height:16px}.IbarOffice__dropdown{background:#fff;border-radius:8px;box-shadow:0 24px 38px #2828281f,0 9px 46px #28282814,0 11px 15px #2828280a;color:#6b6b6b;display:none;max-height:calc(100vh - 64px);opacity:0;overflow:hidden;pointer-events:none;position:absolute;right:calc(72px + var(--ibar-margin-between));top:56px;width:var(--layout-col-5)}.IbarOffice__dropdown::-webkit-scrollbar{-webkit-appearance:none;background:transparent;height:10px;width:10px}.IbarOffice__dropdown::-webkit-scrollbar-thumb{background-color:#28282829;border:3px solid var(--white);border-radius:5px;-webkit-box-shadow:0 0 1px hsla(0,0%,100%,.5)}@-moz-document url-prefix(){.IbarOffice__dropdown{scrollbar-width:thin}}@media only screen and (max-width:1024px){.IbarOffice__dropdown{display:block}}.IbarOffice__dropdown--showScrollbar{overflow-x:hidden;overflow-y:auto}@media only screen and (min-width:1921px){.IbarOffice__dropdown{right:calc(50vw - var(--layout-max-width-px)*.5px + var(--layout-gap) + 32px + var(--ibar-margin-between))}}@media only screen and (max-width:1024px){.IbarOffice__dropdown{opacity:1}}.IbarOffice__dropdown__trigger{color:var(--ibar-color);font-size:.875rem;font-weight:500;line-height:1.25rem;margin-left:var(--ibar-margin-between);position:relative;text-align:right;white-space:nowrap}@media only screen and (max-width:1280px){.IbarOffice__dropdown__trigger{margin-left:24px}}.IbarOffice__dropdown__trigger span{margin-left:8px}.IbarOffice__dropdown__trigger:before{content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;font-size:16px;font-weight:300;height:16px;line-height:16px;vertical-align:text-top;width:16px}@media only screen and (max-width:1280px){.IbarOffice__dropdown__trigger:before{margin-right:0}}@media only screen and (max-width:1024px){.IbarOffice__dropdown__trigger:before{height:24px;width:24px}}.IbarOffice__dropdown__trigger:after{content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;display:inline-block;font-size:12px;font-weight:300;margin-left:8px;transition:transform .3s cubic-bezier(.37,.74,.15,1)}.IbarOffice__dropdown__trigger--open,.IbarOffice__dropdown__trigger:hover,.IbarOffice__dropdown__trigger:hover:after{color:var(--ibar-color-hover)}@media only screen and (max-width:1024px){.IbarOffice__dropdown__trigger--open{font-weight:700}}.IbarOffice__dropdown__trigger--open:after{transform:rotate(-180deg)}.IbarOffice__dropdown__trigger--open:before{transform:scale(1)}.IbarOffice__dropdown__list{max-height:calc(100vh - 64px);padding:8px 0;position:relative}@media only screen and (max-width:1024px){.IbarOffice__dropdown__list{padding:0}}@media only screen and (max-width:563px){.IbarOffice__dropdown__list{padding-top:40px}}.IbarOffice__dropdown__item a,.IbarOffice__dropdown__item button,.IbarOffice__dropdown__subitemsList a,.IbarOffice__dropdown__subitemsList button{align-items:center;box-sizing:border-box;color:#6b6b6b;display:flex;font-size:.875rem;font-weight:500;justify-content:space-between;line-height:1.25rem;padding:16px 16px 16px 32px;text-align:left;width:100%}@media only screen and (min-width:1024px){.IbarOffice__dropdown__item a:hover,.IbarOffice__dropdown__item button:hover,.IbarOffice__dropdown__subitemsList a:hover,.IbarOffice__dropdown__subitemsList button:hover{background-color:#f7f7f7;color:#282828}.IbarOffice__dropdown__item a:hover:after,.IbarOffice__dropdown__item button:hover:after,.IbarOffice__dropdown__subitemsList a:hover:after,.IbarOffice__dropdown__subitemsList button:hover:after{color:#282828}}.IbarOffice__dropdown__item button.pointerEventsDisabled,.IbarOffice__dropdown__subitemsList button.pointerEventsDisabled{pointer-events:none}.IbarOffice__dropdown__item button:after,.IbarOffice__dropdown__subitemsList button:after{color:var(--grey70);content:"";font-family:Frontiers-Iconography-Next!important;font-size:14px;font-weight:300!important;line-height:14px;-webkit-font-smoothing:antialiased}.IbarOffice__dropdown__subitemsList{display:none;overflow:hidden;padding:8px 0;position:absolute;right:-200%;top:0;width:100%}@media only screen and (max-width:1024px){.IbarOffice__dropdown__subitemsList{display:block}}.IbarOffice__dropdown__subitemsList button{justify-content:flex-start;line-height:inherit}.IbarOffice__dropdown__subitemsList button:after{display:none}.IbarOffice__dropdown__subitemsList button:before{color:var(--grey70);content:"";font-family:Frontiers-Iconography-Next!important;font-size:16px;font-weight:300!important;line-height:16px;-webkit-font-smoothing:antialiased;padding-right:16px}.IbarOffice__dropdown__subitem a{box-sizing:border-box;display:block;font-size:.875rem;font-weight:500;height:100%;line-height:1.25rem;padding:16px 16px 16px 32px;text-align:left;width:100%}@media only screen and (min-width:1024px){.IbarOffice__dropdown__subitem a:hover{background-color:#f7f7f7;color:#282828}}.Ibar__dropdown__list--hidden{left:-360px}.Ibar{--ibar-bg:var(--white);--ibar-border-color:var(--grey20);--ibar-color:var(--grey80);--ibar-color-hover:var(--black);color:var(--ibar-color);--ibar-margin-between:40px}@media only screen and (max-width:1024px){.Ibar{--ibar-margin-between:24px;padding:0}}.Ibar__wrapper{align-items:center;box-sizing:border-box;color:var(--white);display:flex;height:64px;margin:0 auto;max-width:calc(var(--layout-max-width-px)*1px);padding:0 40px;width:100%;z-index:31}@media only screen and (max-width:1024px){.Ibar__wrapper{height:48px;padding:0 var(--layout-gap)}}@media only screen and (max-width:768px){.Ibar__wrapper{max-width:none}}.Ibar__wrapper--journal{height:56px}.Ibar__wrapper--journal .Ibar__dropdown,.Ibar__wrapper--journal .Ibar__link{margin-left:36px}@media only screen and (max-width:1280px){.Ibar__wrapper--journal .Ibar__dropdown,.Ibar__wrapper--journal .Ibar__link{margin-left:24px}}.Ibar__main{background:var(--ibar-bg);border:1px solid var(--ibar-border-color);left:0;position:fixed;top:0;width:100%;z-index:33}@media only screen and (max-width:1024px){.Ibar__main .IbarOffice,.Ibar__main .Ibar__button,.Ibar__main .Ibar__dropdown,.Ibar__main .Ibar__icon--list,.Ibar__main .Ibar__icon--productHub,.Ibar__main .Ibar__link{display:none}.Ibar__main .Ibar__icon{margin-left:24px}.Ibar__main .Ibar__icon:before{color:var(--ibar-color);font-size:24px}}.Ibar__main .Ibar__journalName{border-left:1px solid var(--ibar-color);display:none;font-size:.875rem;line-height:1.25rem;margin-left:16px;margin-top:0;overflow:hidden;padding-left:16px;text-overflow:ellipsis;white-space:nowrap}@media only screen and (max-width:1024px){.Ibar__main .Ibar__journalName{display:block}}@media only screen and (max-width:563px){.Ibar__main .Ibar__journalName{display:none}}@media only screen and (max-width:1024px){.Ibar__main .Ibar__journalName__container{display:none}}.Ibar__link{color:var(--ibar-color);font-size:.875rem;font-weight:500;line-height:1.25rem;margin-left:var(--ibar-margin-between);margin-top:1px;white-space:nowrap}.Ibar__link--active,.Ibar__link:hover{color:var(--ibar-color-hover)}.Ibar__button{align-items:center;border:1px solid var(--ibar-color);border-radius:16px;box-sizing:border-box;color:var(--ibar-color);display:flex;font-size:.875rem;font-weight:700;height:32px;justify-content:center;line-height:1.25rem;margin-left:var(--ibar-margin-between);margin-top:1px;padding:5px 16px;text-align:center;white-space:nowrap}@media only screen and (max-width:1280px){.Ibar__button{font-size:.75rem;line-height:1.0625rem}}.Ibar__button:hover{border-color:var(--ibar-color-hover);color:var(--ibar-color-hover)}.Ibar__spacer{flex:1}.Ibar__journal{background:#f7f7f7;box-shadow:0 1px 2px #2828281f,0 2px 1px #28282814,0 1px 3px #2828280a;left:0;position:fixed;top:64px;width:100%;z-index:32}.Ibar__journal--mix{display:block;top:0;visibility:hidden;z-index:31}.Ibar__journal--mix .Ibar__logo--tenant{display:none}.Ibar__journal--mix .Ibar__logo:not(.Ibar__logo--tenant)+.Ibar__journalName{border-left:1px solid var(--ibar-color);margin-left:16px;margin-right:12px;padding-left:16px}.Ibar__journal--mix .Ibar__journal__maskLogo{height:20px;max-width:80px}.Ibar__journal--mix .Ibar__journalName{font-size:.875rem;line-height:1.25rem;margin-top:0}@media only screen and (max-width:1441px){.Ibar__journal--mix .Ibar__journalName{margin-right:0}}@media only screen and (max-width:1280px){.Ibar__journal--mix .Ibar__journalName{overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.Ibar__journal--mix .Ibar__journalName span:first-child{display:none}}@media only screen and (max-width:1441px){.Ibar__journal--mix .Ibar__button,.Ibar__journal--mix .Ibar__dropdown,.Ibar__journal--mix .Ibar__link{margin-left:32px}}@media only screen and (max-width:1280px){.Ibar__journal--mix .Ibar__button,.Ibar__journal--mix .Ibar__dropdown,.Ibar__journal--mix .Ibar__link{margin-left:24px}.Ibar__journal--mix .Ibar__button span:last-child{display:none}}.Ibar__journal--mix .Ibar__button:nth-last-child(4) span:last-child,.Ibar__journal--mix .Ibar__button:nth-last-child(5) span:last-child{display:none}@media only screen and (max-width:1441px){.Ibar__journal--mix .Ibar__icon,.Ibar__journal--mix .Ibar__userLogged{margin-left:24px}.Ibar__journal--mix .Ibar__wrapper--journal{padding:0 32px}}.Ibar__journal--mix .Ibar__logo{margin-top:-2px;width:auto}.Ibar__journal--mix .Ibar__logo__link--text{margin-top:2px}.Ibar__journal--mix .Ibar__logo__link--logo{margin-top:3px}@media only screen and (max-width:1441px){.Ibar__journal--mix .Ibar__icon span{display:none}}.Ibar__journal--mix .IbarOffice__dropdown{right:86px;top:50px}@media only screen and (max-width:1441px){.Ibar__journal--mix .IbarOffice__dropdown__trigger{margin-left:32px}.Ibar__journal--mix .IbarOffice__dropdown__trigger span,.Ibar__journal--mix .IbarOffice__dropdown__trigger:after{display:none}}@media only screen and (max-width:1280px){.Ibar__journal--mix .IbarOffice__dropdown__trigger{margin-left:24px}}@media only screen and (max-width:1024px){.Ibar__journal{display:none}}.Ibar__journal__maskLogo{border-right:1px solid #6b6b6b;flex-shrink:0;height:24px;margin-right:16px;max-width:96px;padding-right:16px}.Ibar__journal__logo{height:100%;-o-object-fit:contain;object-fit:contain;width:100%}.Ibar__customList{display:flex;margin-left:47px}@media only screen and (max-width:1024px){.Ibar__customList{flex-direction:column;margin-left:0}}.Ibar__customList__li{color:#6b6b6b;font-size:.875rem;font-weight:500;line-height:1.25rem;margin-right:37px}@media only screen and (max-width:1024px){.Ibar__customList__li{padding:24px 0 24px 16px}}.Ibar__customList__li--active{color:#282828}.Ibar__logo{height:24px}.Ibar__logo--tenant{height:auto;min-width:-moz-fit-content;min-width:fit-content;width:auto}.Ibar__logo--tenant span{color:var(--ibar-color);display:inline-block;font-size:.875rem;font-weight:500;line-height:1.25rem;white-space:nowrap}.Ibar__logo--tenant .Ibar__logo__link{height:auto}.Ibar__logo__link{align-content:center;display:flex;height:24px;justify-content:left}.Ibar__logo__link__tenantLogo{display:inline-block;height:24px;max-width:220px}.Ibar__logo__productName{align-items:center;border-left:1px solid var(--grey40);color:#545454;display:flex;font-size:1.125rem;font-weight:500;justify-content:center;line-height:1.75rem;margin-left:16px;padding-left:16px}.Ibar__logo__svg{height:100%;width:auto}.Ibar__logo__text{fill:var(--ibar-color)}.Ibar__burger{display:none}@media only screen and (max-width:1024px){.Ibar__burger{display:block;height:24px;margin-right:24px;width:24px}.Ibar__burger:after{content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;color:var(--ibar-color-hover);font-size:24px;line-height:24px}}.Ibar__journalName{color:var(--ibar-color);font-size:1.125rem;font-weight:500;line-height:1.75rem;margin-right:4px;margin-top:-1px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.Ibar__journalName__container{align-items:center;display:flex}.Ibar__journalName:active{color:var(--ibar-color)}@media only screen and (max-width:1441px){.Ibar__journalName{margin-right:0}}.Ibar__icon{color:var(--ibar-color);cursor:pointer;font-size:.875rem;font-weight:500;line-height:1.25rem;margin-left:var(--ibar-margin-between);max-height:24px;max-width:96px;white-space:nowrap}@media only screen and (max-width:1280px){.Ibar__icon{margin-left:24px}}.Ibar__icon:active{color:var(--ibar-color)}.Ibar__icon:before{content:"";font-family:Frontiers-Iconography-Next!important;-webkit-font-smoothing:antialiased;font-size:16px;font-weight:300;height:16px;line-height:16px;vertical-align:text-top;width:16px}@media only screen and (max-width:1280px){.Ibar__icon:before{margin-right:0}}@media only screen and (max-width:1024px){.Ibar__icon:before{align-items:center;display:flex;height:24px;width:24px}}.Ibar__icon span{margin-left:8px}@media only screen and (max-width:1024px){.Ibar__icon 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<style>.CardSubject{background-color:var(--white);border-radius:8px;display:flex;flex-direction:column;padding:24px 24px 16px;transition:box-shadow .48s cubic-bezier(.37,.74,.15,1);width:100%}.CardSubject:hover{box-shadow:0 0 17px #2828281f,0 0 22px #28282814,0 0 8px #2828280a}.CardSubject__wrapper,.CardSubject__wrapper__link{display:flex;width:100%}.CardSubject__title{font-size:1rem;font-weight:500;line-height:1.375rem;margin-bottom:16px}@media only screen and (max-width:1024px){.CardSubject__title{font-size:.875rem;font-weight:500;line-height:1.25rem}}.CardSubject__icon:after{color:var(--maincolor50);content:"";font-family:Frontiers-Iconography-Next!important;font-size:24px;font-weight:300!important;line-height:24px;-webkit-font-smoothing:antialiased;vertical-align:middle}@media only screen and 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.FeedbackIcon{height:16px;width:16px}}.Alert__main{align-items:center;display:flex;display:inline-flex;grid-column:2/3;grid-row:1/2;justify-content:space-between;width:100%}.Alert__main:before{--icon-color:var(--green50);--border-color:var(--green20);align-self:flex-start;background:radial-gradient(circle at center,var(--black) 35%,transparent,transparent 100%);font-family:Frontiers-Iconography-Next!important;font-size:14px;margin-right:8px;margin-top:4px}@media only screen and (max-width:1024px){.Alert__main:before{margin-top:2px}}.Alert__main__message{color:var(--black);font-size:1rem;font-weight:500;line-height:1.375rem;line-height:22px;margin-bottom:0;margin-top:0;width:100%}@media only screen and (max-width:1024px){.Alert__main__message{font-size:.875rem;font-weight:500;line-height:1.25rem}}@media only screen and (max-width:563px){.Alert__main{align-items:flex-start;flex-direction:column;gap:15px}.Alert__main button:not(.Alert__message__close){align-self:flex-end;width:calc(100% - 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<style>.UgaritInput{max-width:100%;min-width:100px;position:relative}.UgaritInput__wrapper{max-width:100%;min-height:48px;position:relative}.UgaritInput.is-filter-error .UgaritInput__input{border-color:#d51a2c;color:#d51a2c}.UgaritInput__createForm{background:var(--white);border:1px solid var(--grey40);border-radius:8px;box-shadow:0 4px 5px #2828281f,0 1px 10px #28282814,0 2px 4px #2828280a;padding:24px;z-index:11}.UgaritInput__createForm,.UgaritInput__hint{box-sizing:border-box;position:absolute;width:100%}.UgaritInput__hint{color:#6b6b6b;font-size:.625rem;font-weight:300;left:0;line-height:.875rem;top:calc(100% + 4px);z-index:1}.UgaritInput__icon{cursor:pointer;height:36px;position:absolute;right:2px;top:5px;width:36px;z-index:2}.UgaritInput__icon:after{color:var(--grey70);font-family:Frontiers-Iconography-Next!important;font-size:16px;height:16px;left:calc(50% - 8px);position:absolute;top:calc(50% - 8px);width:16px}.UgaritInput__icon--reset:after{content:""}.UgaritInput__suggestionsWrapper{background:var(--white);border:1px solid var(--grey60);border-radius:8px;box-sizing:border-box;opacity:0;overflow:hidden;pointer-events:none;position:absolute;top:calc(100% + 6px);transition:box-shadow .24s cubic-bezier(.37,.74,.15,1);width:100%;z-index:10}.UgaritInput__suggestionsWrapper--show{box-shadow:0 12px 17px #2828281f,0 5px 22px #28282814,0 7px 8px #2828280a;opacity:1;pointer-events:all;position:absolute;z-index:220}.UgaritInput__suggestionsWrapper--spinner{min-height:112px}.UgaritInput__suggestionsWrapper--spinner:after{background:#ffffffb3;border-radius:8px;content:"";height:100%;left:0;position:absolute;top:0;width:100%}.UgaritInput__suggestionsWrapper--noItems{border-top:0}.UgaritInput__spinner{height:32px;left:calc(50% - 16px);position:absolute;top:calc(50% - 16px);width:32px;z-index:1}.UgaritInput__spinner:after{animation:rotate 1.5s linear infinite 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<style>.Banner{align-items:flex-start;display:flex;flex-direction:row}@media only screen and (max-width:1024px){.Banner{flex-direction:column}}.Banner__info{display:flex;flex:1;flex-direction:column;padding-right:calc(var(--layout-col-1) + var(--layout-gap)*2);text-align:left}@media only screen and (max-width:1024px){.Banner__info{padding:0;text-align:center}}.Banner__pretitle{color:#282828;font-size:.75rem;font-weight:700;line-height:1.0625rem;margin-bottom:16px}.Banner__title{color:#282828;font-size:1.75rem;font-weight:500;line-height:2.4375rem;margin-bottom:24px}@media only screen and (max-width:1441px){.Banner__title{font-size:1.5rem;line-height:2.0625rem}}.Banner__text{color:#545454;font-size:1rem;font-weight:300;line-height:1.375rem;margin-bottom:24px}.Banner__text p:not([class]):last-of-type{margin-bottom:0}@media only screen and (max-width:1441px){.Banner__text{font-size:1.5rem;line-height:2.0625rem}}@media only screen and 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(max-width:1441px){.CardB__text{font-size:.875rem;font-weight:300;line-height:1.25rem}}.CardB__img{flex-shrink:0;height:202px;margin:0;overflow:hidden;position:relative}@media only screen and (max-width:1441px){.CardB__img{height:156px}}@media only screen and (max-width:1280px){.CardB__img{height:138px}}@media only screen and (max-width:1024px){.CardB__img{height:150px;width:var(--layout-col-8)}}@media only screen and (max-width:768px){.CardB__img{height:156px;width:var(--layout-col-6)}}@media only screen and (max-width:563px){.CardB__img{height:198px;width:100%}}.CardB__img .is-inside-mask{position:absolute}</style> <style>.FilterCardB__list{-moz-column-gap:32px;column-gap:32px;display:grid;grid-template-columns:repeat(4,1fr);row-gap:32px}@media only screen and (max-width:1024px){.FilterCardB__list{grid-template-columns:repeat(1,1fr);row-gap:24px}}.FilterCardB--layoutOddCards .CardB:first-child{grid-column:span 4}@media only screen and (max-width:1024px){.FilterCardB--layoutOddCards 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(max-width:1024px){.FilterCardB--layoutOddCards .CardB:first-child .CardB__title{display:block;font-size:1.5rem;font-weight:500;line-height:2.0625rem;max-width:100%;-webkit-line-clamp:none;-moz-line-clamp:none;line-clamp:none}}.FilterCardB--layoutOddCards .CardB:first-child .CardB__text{display:-webkit-box;max-width:100%;-webkit-line-clamp:10;-webkit-box-orient:vertical;-moz-line-clamp:10;overflow:hidden;text-overflow:ellipsis}@media only screen and (max-width:1441px){.FilterCardB--layoutOddCards .CardB:first-child .CardB__text{display:-webkit-box;max-width:100%;-webkit-line-clamp:5;-webkit-box-orient:vertical;-moz-line-clamp:5;overflow:hidden;text-overflow:ellipsis}}@media only screen and (max-width:1280px){.FilterCardB--layoutOddCards .CardB:first-child .CardB__text{display:-webkit-box;max-width:100%;-webkit-line-clamp:3;-webkit-box-orient:vertical;-moz-line-clamp:3;overflow:hidden;text-overflow:ellipsis}}@media only screen and (max-width:1024px){.FilterCardB--layoutOddCards 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auto}}.MessagesCarousel__item__title{flex-shrink:0;font-size:2rem;font-weight:500;line-height:2.75rem;width:var(--layout-col-10)}.MessagesCarousel__item__title em,.MessagesCarousel__item__title strong{color:var(--maincolor40);font-style:normal;font-weight:500}@media only screen and (max-width:1280px){.MessagesCarousel__item__title{font-size:1.75rem;line-height:2.4375rem}}@media only screen and (max-width:1024px){.MessagesCarousel__item__title{font-size:1.5rem;line-height:2.0625rem;margin-bottom:24px;text-align:center;width:100%}}@media only screen and (max-width:563px){.MessagesCarousel__item__title{font-size:1.25rem;line-height:1.75rem;margin-bottom:16px}}.MessagesCarousel__item__content{flex-shrink:0;width:var(--layout-col-8)}@media only screen and (max-width:1024px){.MessagesCarousel__item__content{text-align:center;width:100%}}.MessagesCarousel__item__text{color:#6b6b6b;font-size:1.125rem;font-weight:300;line-height:1.75rem;margin-bottom:32px}.MessagesCarousel__item__text 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class="Ibar__journalName__container" logoclass="Ibar__logo--mixed"><div class="Ibar__journal__maskLogo" style="display:none;"><img class="Ibar__journal__logo" src></div><div class="Ibar__journalName"><span>Frontiers in</span><span> Neuroscience</span></div></div></a><div class="Ibar__spacer"></div><div parent-data-event="iBarJournal"><div class="Ibar__dropdown"><button class="Ibar__dropdown__trigger"> Sections</button><div class="Ibar__dropdown__menu"><div class="Ibar__dropdown__menu__header"><button class="Ibar__dropdown__menu__header__title" aria-label="Close Dropdown">Sections</button><button class="Ibar__close" aria-label="Close Dropdown"></button></div><ul class="Ibar__dropdown__sections"><li class="Ibar__dropdown__sections__item"><a href="/journals/neuroscience/sections/auditory-cognitive-neuroscience" data-event="iBarJournal-sections-a_id_65">Auditory Cognitive Neuroscience</a></li><li class="Ibar__dropdown__sections__item"><a 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class="Ibar__button Ibar__submit" href="https://www.frontiersin.org/submission/submit?domainid=1&fieldid=55&specialtyid=0&entitytype=2&entityid=1" data-event="iBarJournal-a-submit"><span>Submit</span><span> your research</span></a><a class="Ibar__icon Ibar__icon--search" href="//www.frontiersin.org/search" aria-label="Search" target="_self" data-event="iBar-a-search"><span>Search</span></a><div class="Ibar__userArea"></div></div></div></nav><header class="MainHeader"><div class="MainHeader__ibar"></div><div class="MainHeader__body"><ul class="Breadcrumbs"><li class="Breadcrumbs__item"><div class="Breadcrumbs__separator"></div><a href="/" aria-label="Home" target="_self" data-event="breadcrumbs-item-a_home" class="Breadcrumbs__item__text"><span class="Breadcrumbs__home"></span></a></li><li class="Breadcrumbs__item"><div class="Breadcrumbs__separator"></div><a href="https://www.frontiersin.org/journals/neuroscience" aria-label="Frontiers in Neuroscience" target="_self" 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class="MainHeader__title">Biological Drivers, Effects, and Mechanisms of Psychedelic-Induced Behavioral Change</h3></div><div class="MainHeader__actions"><div class="MainHeader__actionsWrapper"><ul class="Metrics"><li class="Metrics__numbers__item"><div><div class="Metrics__numbers__line"></div><div class="Metrics__numbers__mask"><p class="Metrics__numbers__main"><span class="Metrics__numbers__number">382</span></p><p class="Metrics__numbers__text">Total views and downloads</p></div></div></li></ul><div class="MainHeader__buttons"><a href="https://www.frontiersin.org/research-topics/66462/biological-drivers-effects-and-mechanisms-of-psychedelic-induced-behavioral-change/participate-in-open-access-research-topic" rel="noopener noreferrer" class="HeaderImpactLink MainHeader__link HeaderImpactLink--closedButton" data-v-553a0f4c><span data-v-553a0f4c>Participate in this topic</span></a><button class="MainHeader__link HeaderImpactLink--withArrowRight HeaderImpactLink--closedButton 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aria-selected="false" tabindex="-1"><div class="Tabs__title"><span class="Tabs__label Tabs__label--md">Articles</span></div></button><button id="Authors-2" class="Tabs__tab Tabs__tab--md" role="tab" aria-label="Authors" aria-selected="false" tabindex="-1"><div class="Tabs__title"><span class="Tabs__label Tabs__label--md">Authors</span></div></button><button id="Impact-3" class="Tabs__tab Tabs__tab--md" role="tab" aria-label="Impact" aria-selected="false" tabindex="-1"><div class="Tabs__title"><span class="Tabs__label Tabs__label--md">Impact</span></div></button></div></div></div></div><section aria-labelledby="Overview-0" role="tabpanel" tabindex="0" class="content content-Overview"><section class="content__main"><div class="RTOverview"><section><h2 class="Section__title"> About this Research Topic</h2><article class="Alert Alert--info"><div class="Alert__icon"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 48 48" width="24px" class="FeedbackIcon"><path fill="#fff" d="M10 10h28v28H10z"></path><path fill="var(--blue50)" d="M24 2.88a21.12 21.12 0 1 0 0 42.24 21.12 21.12 0 0 0 0-42.24ZM22.08 13.4a.96.96 0 0 1 .96-.96h1.92a.96.96 0 0 1 .96.96v1.92a.96.96 0 0 1-.96.96h-1.92a.96.96 0 0 1-.96-.96V13.4Zm5.76 21.2a.96.96 0 0 1-.96.97h-5.76a.96.96 0 0 1-.96-.96v-1.92a.96.96 0 0 1 .96-.96h.96v-7.68h-.96a.96.96 0 0 1-.96-.96v-1.92a.96.96 0 0 1 .96-.96h3.84a.96.96 0 0 1 .96.96v10.56h.96a.96.96 0 0 1 .96.96v1.92Z"></path></svg></div><div class="Alert__main"><p class="Alert__message">Submission deadlines</p></div><ol class="Alert__info"><li class="Alert__infoItem"><p class="Alert__infoItem__text">Manuscript Summary Submission Deadline 28 March 2025 | Manuscript Submission Deadline 18 July 2025</p></li><li class="Alert__infoItem"><p class="Alert__infoItem__text">This Research Topic is still accepting articles.</p><ol class="Alert__infoItem__links"><li><span class="Link__wrapper"><a class="Link Link--linkType Link--grey Link--small Link--icon Link--chevronRight Link--right" aria-label="Check author guidelines" href="https://www.frontiersin.org/about/author-guidelines"><span>Check author guidelines</span></a></span></li></ol></li></ol></article><div class="RTOverviewBackground"><h4 class="RTOverviewBackground__title">Background</h4><div class="RTOverviewBackground__expandable"><p>We are pleased to announce this Research Topic in Frontiers in Neuroscience, dedicated to exploring the biological underpinnings, effects, and mechanisms of psychedelic-induced behavioral change, in both pre-clinical and clinical studies. Psychedelics have garnered significant interest for their potential to induce profound and lasting changes in behavior, and understanding how these substances interact with biological systems is crucial for harnessing their therapeutic potential<br><br>The primary aim of this Research Topic is to provide a multidisciplinary examination of how psychedelics influence biological systems to produce immediate and/or lasting changes in behavior. By addressing this topic, we hope to advance our understanding of the complex interplay between psychedelics and biological processes, and how these interactions translate into behavioral outcomes. Insights gained from this research could pave the way for novel therapeutic approaches for mental health conditions such as PTSD, depression, and anxiety. We encourage contributions that explore various aspects of these interactions, from genetic and epigenetic influences to neurobiological mechanisms and physiological responses.<br><br>This Research Topic will focus on the latest research findings that elucidate the interplay between psychedelics and biological processes, and how these translated into behavioral outcomes. We welcome submissions that address, but are not limited to, the following topics:<br><br>• Genetic and Epigenetic Influences:<br><br>o Studies investigating how genetic variations affect individual responses to psychedelic compounds.<br><br>o Research on epigenetic modifications induced by psychedelics and their long-term implications for behavior.<br><br>• Neurobiological Mechanisms:<br><br>o Insights into the neural circuits and neurotransmitter systems modulated by psychedelics.<br><br>o Mechanistic studies on the role of psychedelics in neuroplasticity and synaptogenesis.<br><br>• Physiological and Psychological Responses:<br><br>o Examination of the physiological pathways activated by psychedelics and their correlation with psychological experiences.<br><br>o Investigations into the acute and chronic biological effects mediating the psychological impact on mental health conditions such as PTSD, depression, and anxiety.<br><br>• Molecular and Cellular Studies:<br><br>o Research on the impact of psychedelics at the molecular and cellular levels, including receptor binding and intracellular signaling.<br><br>o Studies on the role of immune and inflammatory pathways in mediating the effects of psychedelics.<br><br>• Behavioral Change and Integration:<br><br>o Longitudinal studies tracking behavioral changes post-psychedelic treatment and their integration into daily life.<br><br>o Comparative studies on the efficacy of different psychedelic compounds, focusing on their varying pharmacological actions.<br><br>• Novel Methods of Acute Effects:<br><br>o Studies in animals or humans measuring the acute effects of psychedelics with metrics other than self-report.<br><br>We are interested in a variety of manuscript types, including Original Research articles, Review articles, and Brief Research Reports. We look forward to your valuable contributions to this exciting and rapidly evolving field.</p><div class="RTOverviewBackground__expandable__secondary"><section id="ArticleTypesSection"><h4>Article types and fees</h4><p> This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description: </p><ul><li>Brief Research Report</li><li>Case Report</li><li>Clinical Trial</li><li>Community Case Study</li><li>Data Report</li><li>Editorial</li><li>General Commentary</li><li>Hypothesis and Theory</li><li>Methods</li><li><button type="button" class="Button Button--linkButton Button--maincolor Button--medium ArticleTypesSection__Modal--viewAll" data-event="btn-action"><span>... View all formats</span></button></li></ul><p>Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders. </p></section><div class="Modal Modal--noFooter"><button aria-label="Close modal" class="Modal__overlay" data-event="modal-overlay-close"></button><div class="Modal__container"><div class="Modal__header"><h3 class="Modal__title">Article types</h3><button aria-label="Close modal" class="Modal__close" data-event="modal-button-close"></button></div><div class="Modal__body"><p> This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description: </p><ul><li>Brief Research Report</li><li>Case Report</li><li>Clinical Trial</li><li>Community Case Study</li><li>Data Report</li><li>Editorial</li><li>General Commentary</li><li>Hypothesis and Theory</li><li>Methods</li><li>Mini Review</li><li>Opinion</li><li>Original Research</li><li>Perspective</li><li>Review</li><li>Study Protocol</li><li>Systematic Review</li><li>Technology and Code</li></ul></div></div></div><div class="RTOverviewBackground__keywords"><p><strong>Keywords: </strong>Psychedelics, Behavioral Change, Neurobiological Mechanisms, Epigenetic Modifications, Mental Health Conditions</p><p><strong>Important note: </strong> All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review. </p></div></div></div></div><button type="button" class="Button Button--linkButton Button--maincolor Button--medium Button--icon Button--chevronDown Button--right" data-event="btn-action"><span>Show more</span></button></section><div id="topic-editors" class="Overview__Authors"><h2>Topic editors</h2><ul class="Overview__Authors__Cards"><li><article class="CardEditor CardEditor--noMoreInfo"><a class="CardEditor__wrapper" href="https://loop.frontiersin.org/people/180731" target="_blank" data-event="cardEditor-a-180731"><div class="CardEditor__info"><figure class="CardEditor__mask"><figure class="Avatar Avatar--size-96"><img class="Avatar__img is-inside-mask" src="https://loop.frontiersin.org/images/profile/180731/55" alt="Sarah E Mennenga"></figure></figure><div class="CardEditor__detail notranslate"><h3 class="CardEditor__name">sarah e mennenga</h3><p class="CardEditor__affiliation__name">Arizona State University</p><p class="CardEditor__affiliation__location"><span>Tempe</span>, <span>United States</span></p></div></div></a></article></li><li><article class="CardEditor CardEditor--noMoreInfo"><a class="CardEditor__wrapper" href="https://loop.frontiersin.org/people/79697" target="_blank" data-event="cardEditor-a-79697"><div class="CardEditor__info"><figure class="CardEditor__mask"><figure class="Avatar Avatar--size-96"><img class="Avatar__img is-inside-mask" src="https://loop.frontiersin.org/images/profile/79697/55" alt="Candace R. Lewis"></figure></figure><div class="CardEditor__detail notranslate"><h3 class="CardEditor__name">candace r. lewis</h3><p class="CardEditor__affiliation__name">Arizona State University</p><p class="CardEditor__affiliation__location"><span>Tempe</span>, <span>United States</span></p></div></div></a></article></li><li><article class="CardEditor CardEditor--noMoreInfo"><a class="CardEditor__wrapper" href="https://loop.frontiersin.org/people/47889" target="_blank" data-event="cardEditor-a-47889"><div class="CardEditor__info"><figure class="CardEditor__mask"><figure class="Avatar Avatar--size-96"><img class="Avatar__img is-inside-mask" src="https://loop.frontiersin.org/images/profile/47889/55" alt="Daniela Kaufer"></figure></figure><div class="CardEditor__detail notranslate"><h3 class="CardEditor__name">daniela kaufer</h3><p class="CardEditor__affiliation__name">University of California, Berkeley</p><p class="CardEditor__affiliation__location"><span>Berkeley</span>, <span>United States</span></p></div></div></a></article></li></ul></div><section id="FAQs"><h2>Frequently asked questions</h2><ul class="Accordion"><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">What is a Research Topic? </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Frontiers' Research Topics are collaborative hubs built around an emerging theme.Defined, managed, and led by renowned researchers, they bring communities together around a shared area of interest to stimulate collaboration and innovation.</p><p>Unlike section journals, which serve established specialty communities, Research Topics are pioneer hubs, responding to the evolving scientific landscape and catering to new communities.</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">Why does Frontiers publish Research Topics?  </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>The goal of Frontiers' publishing program is to empower research communities to actively steer the course of scientific publishing. Our program was implemented as a three-part unit with fixed field journals, flexible specialty sections, and dynamically emerging Research Topics, connecting communities of different sizes and maturity.</p><p>Research Topics originate from the scientific community. Many of our Research Topics are suggested by existing editorial board members who have identified critical challenges or areas of interest in their field. </p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">Why are Research Topics important for journals?</div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>As an editor, Research Topics will help you build your journal, as well as your community, around emerging, cutting-edge research. As research trailblazers, Research Topics attract high-quality submissions from leading experts all over the world.</p><p>A thriving Research Topic can potentially evolve into a new specialty section if there is sustained interest and a growing community around it.</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">How do we ensure the quality of articles within Research Topics?</div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Each Research Topic must be approved by the specialty chief editor, and it falls under the editorial oversight of our editorial boards, supported by our in-house research integrity team. The same standards and rigorous peer review processes apply to articles published as part of a Research Topic as for any other article we publish.</p><p>In 2023, 80% of the Research Topics we published were edited or co-edited by our editorial board members, who are already familiar with their journal's scope, ethos, and publishing model. All other topics are guest edited by leaders in their field, each vetted and formally approved by the specialty chief editor.</p> </div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">What are the benefits of publishing my article in a Research Topic?</div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Publishing your article within a Research Topic with other related articles increases its discoverability and visibility, which can lead to more views, downloads, and citations. Research Topics grow dynamically as more published articles are added, causing frequent revisiting, and further visibility.</p><p>As Research Topics are multidisciplinary, they are cross-listed in several fields and section journals – increasing your reach even more and giving you the chance to expand your network and collaborate with researchers in different fields, all focusing on expanding knowledge around the same important topic.</p><p>Our larger Research Topics are also converted into ebooks and receive social media promotion from our digital marketing team.</p> </div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">What types of articles can be published in a Research Topic? </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Frontiers offers multiple article types, but it will depend on the field and section journals in which the Research Topic will be featured. The available article types for a Research Topic will appear in the drop-down menu during the submission process.</p><p><a href="https://www.frontiersin.org/journals/neuroscience/for-authors/article-types">Check available article types here </a></p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">Can I suggest a new Research Topic?  </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Yes, we would love to hear your ideas for a topic. Most of our Research Topics are community-led and suggested by researchers in the field. Our in-house editorial team will contact you to talk about your idea and whether you’d like to edit the topic. If you’re an early-stage researcher, we will offer you the opportunity to coordinate your topic, with the support of a senior researcher as the topic editor. </p> <p><a href="https://researchtopics.frontiersin.org/submit">Suggest your topic here </a></p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">Who leads a Research Topic?  </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>A team of guest editors (called topic editors) lead their Research Topic. This editorial team oversees the entire process, from the initial topic proposal to calls for participation, the peer review, and final publications.</p><p>The team may also include topic coordinators, who help the topic editors send calls for participation, liaise with topic editors on abstracts, and support contributing authors. In some cases, they can also be assigned as reviewers.</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">What is the role of a topic editor?</div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>As a topic editor (TE), you will take the lead on all editorial decisions for the Research Topic, starting with defining its scope. This allows you to curate research around a topic that interests you, bring together different perspectives from leading researchers across different fields and shape the future of your field. </p>  <p>You will choose your team of co-editors, curate a list of potential authors, send calls for participation and oversee the peer review process, accepting or recommending rejection for each manuscript submitted.</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">What support will I receive when editing a new Research Topic?  </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>As a topic editor, you're supported at every stage by our in-house team. You will be assigned a single point of contact to help you on both editorial and technical matters. Your topic is managed through our user-friendly online platform, and the peer review process is supported by our industry-first AI review assistant (AIRA).</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">As a junior researcher, can I be involved in editing a Research Topic? </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>If you’re an early-stage researcher, we will offer you the opportunity to coordinate your topic, with the support of a senior researcher as the topic editor. This provides you with valuable editorial experience, improving your ability to critically evaluate research articles and enhancing your understanding of the quality standards and requirements for scientific publishing, as well as the opportunity to discover new research in your field, and expand your professional network.</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">Can I get a certificate for editing a Research Topic?</div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Yes, certificates can be issued on request. We are happy to provide a certificate for your contribution to editing a successful Research Topic.</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">Who will I collaborate with?</div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Research Topics thrive on collaboration and their multi-disciplinary approach around emerging, cutting-edge themes, attract leading researchers from all over the world.</p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">How long does it take to publish a Research Topic?</div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>As a topic editor, you can set the timeline for your Research Topic, and we will work with you at your pace. Typically, Research Topics are online and open for submissions within a few weeks and remain open for participation for 6 – 12 months. Individual articles within a Research Topic are published as soon as they are ready.</p><p>Find out more <a href="https://www.frontiersin.org/about/research-topics">about our Research Topics</a></p></div></div></li><li class="Accordion__item"><button class="Accordion__headline"><div class="Accordion__title">What fee support is available to authors publishing in a Research Topic? </div><div class="Accordion__space"></div><div class="Accordion__arrow"></div></button><div class="Accordion__content Accordion__content--fadeOut" style="height:0px;"><div><p>Our fee support program ensures that all articles that pass peer review, including those published in Research Topics, can benefit from open access – regardless of the author's field or funding situation.</p><p>Authors and institutions with insufficient funding can apply for a discount on their publishing fees. 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Participating Journals </h4><ul class="RtSidePanel__Section__OtherParticipatingJournals"><li><a href="/journals/pharmacology"><p class="journalTitle">Frontiers in Pharmacology</p></a><ul class="RtSidePanel__Section__SectionList"><li><a href="/journals/pharmacology/sections/neuropharmacology"><span>Neuropharmacology</span></a></li></ul><ul class="journalMetricsList"><li><span>4.4</span> impact factor </li><li><span>7.8</span> citescore </li></ul></li></ul></section><section id="SubmitSection" class="RtSidePanel__Section" data-v-b5c83da8><p data-v-b5c83da8> Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal. </p><button type="button" class="Button Button--maincolor Button--medium" data-event="btn-action" data-v-b5c83da8><span>Submit</span></button></section><div class="Modal SubmitIdeaDialog" data-v-b5c83da8><button aria-label="Close modal" class="Modal__overlay" data-event="modal-overlay-close"></button><div 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All rights reserved","https://www.frontiersin.org/legal/terms-and-conditions","https://www.frontiersin.org/legal/privacy-policy",{"overviewArticles":341},[],["Reactive",343],{"$ssite-config":344},{"description":345,"env":346,"name":347,"url":348},"This project hosts the landing page of a selected Research Topic with all of it information.","production","research-topics-detail","https://rt-details-2023.frontiersin.org/",["Set"],["ShallowReactive",351],{"ibar-footer":15,"overview":15},"/research-topics/66462/biological-drivers-effects-and-mechanisms-of-psychedelic-induced-behavioral-change",["Reactive",354],{"main":355,"environmentConfig":594,"terminology":598,"authStore":1618},{"currentResearchTopic":356,"primaryJournal":532,"totalArticles":358,"totalAuthors":358,"rtSponsorship":582,"breadCrumbItems":583},{"abstractSubmissionDeadline":357,"authorsCount":358,"onlineSince":359,"closedOn":-1,"createdDate":360,"description":361,"id":362,"impactV5":363,"imageUrl":-1,"availableEbooks":365,"isOpenForManuscriptSubmission":102,"isOpenForSubmission":102,"keywords":366,"journals":382,"manuscriptSubmissionExtendedDeadline":483,"manuscriptSubmissionDeadline":484,"slug":485,"stageId":104,"title":486,"topicCoordinators":487,"topicEditors":488},["Date","2025-03-28T00:00:00.000Z"],0,"Mon Nov 18 2024 16:00:16 GMT+0000 (Coordinated Universal Time)",["Date","2024-07-24T12:16:51.000Z"],"We are pleased to announce this Research Topic in Frontiers in Neuroscience, dedicated to exploring the biological underpinnings, effects, and mechanisms of psychedelic-induced behavioral change, in both pre-clinical and clinical studies. Psychedelics have garnered significant interest for their potential to induce profound and lasting changes in behavior, and understanding how these substances interact with biological systems is crucial for harnessing their therapeutic potential\u003Cbr/>\u003Cbr/>The primary aim of this Research Topic is to provide a multidisciplinary examination of how psychedelics influence biological systems to produce immediate and/or lasting changes in behavior. By addressing this topic, we hope to advance our understanding of the complex interplay between psychedelics and biological processes, and how these interactions translate into behavioral outcomes. Insights gained from this research could pave the way for novel therapeutic approaches for mental health conditions such as PTSD, depression, and anxiety. We encourage contributions that explore various aspects of these interactions, from genetic and epigenetic influences to neurobiological mechanisms and physiological responses.\u003Cbr/>\u003Cbr/>This Research Topic will focus on the latest research findings that elucidate the interplay between psychedelics and biological processes, and how these translated into behavioral outcomes. We welcome submissions that address, but are not limited to, the following topics:\u003Cbr/>\u003Cbr/>•\tGenetic and Epigenetic Influences:\u003Cbr/>\u003Cbr/>o\tStudies investigating how genetic variations affect individual responses to psychedelic compounds.\u003Cbr/>\u003Cbr/>o\tResearch on epigenetic modifications induced by psychedelics and their long-term implications for behavior.\u003Cbr/>\u003Cbr/>•\tNeurobiological Mechanisms:\u003Cbr/>\u003Cbr/>o\tInsights into the neural circuits and neurotransmitter systems modulated by psychedelics.\u003Cbr/>\u003Cbr/>o\tMechanistic studies on the role of psychedelics in neuroplasticity and synaptogenesis.\u003Cbr/>\u003Cbr/>•\tPhysiological and Psychological Responses:\u003Cbr/>\u003Cbr/>o\tExamination of the physiological pathways activated by psychedelics and their correlation with psychological experiences.\u003Cbr/>\u003Cbr/>o\tInvestigations into the acute and chronic biological effects mediating the psychological impact on mental health conditions such as PTSD, depression, and anxiety.\u003Cbr/>\u003Cbr/>•\tMolecular and Cellular Studies:\u003Cbr/>\u003Cbr/>o\tResearch on the impact of psychedelics at the molecular and cellular levels, including receptor binding and intracellular signaling.\u003Cbr/>\u003Cbr/>o\tStudies on the role of immune and inflammatory pathways in mediating the effects of psychedelics.\u003Cbr/>\u003Cbr/>•\tBehavioral Change and Integration:\u003Cbr/>\u003Cbr/>o\tLongitudinal studies tracking behavioral changes post-psychedelic treatment and their integration into daily life.\u003Cbr/>\u003Cbr/>o\tComparative studies on the efficacy of different psychedelic compounds, focusing on their varying pharmacological actions.\u003Cbr/>\u003Cbr/>•\tNovel Methods of Acute Effects:\u003Cbr/>\u003Cbr/>o\tStudies in animals or humans measuring the acute effects of psychedelics with metrics other than self-report.\u003Cbr/>\u003Cbr/>We are interested in a variety of manuscript types, including Original Research articles, Review articles, and Brief Research Reports. 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