Nature - Not Found

<!DOCTYPE html> <html lang="en">  <head> <title>Nature - Not Found</title> <meta http-equiv="X-UA-Compatible" content="IE=edge"/> <meta name="viewport" content="width=device-width,initial-scale=1.0,maximum-scale=2.5,user-scalable=yes"/> <script> (function (e) { var t = e.documentElement, n = e.implementation; t.className = 'js'; if (n && n.hasFeature('http://www.w3.org/TR/SVG11/feature#Image', '1.1')) { t.className += ' svg' } })(document) </script> <meta name="theme-color" content="#940720"> <style> html { font-family: sans-serif; line-height: 1.15; -ms-text-size-adjust: 100%; -webkit-text-size-adjust: 100% } body { margin: 0 } article, aside, footer, header, nav, section { display: block } h1 { font-size: 2em; margin: .67em 0 } figcaption, figure, main { display: block } figure { margin: 1em 40px } hr { box-sizing: content-box; height: 0; overflow: visible } pre { font-family: monospace, monospace; font-size: 1em } a { background-color: transparent; -webkit-text-decoration-skip: objects } a:active, a:hover { outline-width: 0 } abbr[title] { border-bottom: none; text-decoration: underline; text-decoration: underline dotted } b, strong { font-weight: inherit } b, strong { font-weight: bolder } code, kbd, samp { font-family: monospace, monospace; font-size: 1em } dfn { font-style: italic } mark { background-color: #ff0; color: #000 } small { font-size: 80% } sub, sup { font-size: 75%; line-height: 0; position: relative; vertical-align: baseline } sub { bottom: -.25em } sup { top: -.5em } audio, video { display: inline-block } audio:not([controls]) { display: none; height: 0 } img { border-style: none } svg:not(:root) { overflow: hidden } button, input, optgroup, select, textarea { font-family: sans-serif; font-size: 100%; line-height: 1.15; margin: 0 } button, input { overflow: visible } button, select { text-transform: none } button, html [type=button], [type=reset], [type=submit] { -webkit-appearance: button } button::-moz-focus-inner, [type=button]::-moz-focus-inner, [type=reset]::-moz-focus-inner, [type=submit]::-moz-focus-inner { border-style: none; padding: 0 } button:-moz-focusring, [type=button]:-moz-focusring, [type=reset]:-moz-focusring, [type=submit]:-moz-focusring { outline: 1px dotted ButtonText } fieldset { border: 1px solid silver; margin: 0 2px; padding: .35em .625em .75em } legend { box-sizing: border-box; color: inherit; display: table; max-width: 100%; padding: 0; white-space: normal } progress { display: inline-block; vertical-align: baseline } textarea { overflow: auto } [type=checkbox], [type=radio] { box-sizing: border-box; padding: 0 } [type=number]::-webkit-inner-spin-button, [type=number]::-webkit-outer-spin-button { height: auto } [type=search] { -webkit-appearance: textfield; outline-offset: -2px } [type=search]::-webkit-search-cancel-button, [type=search]::-webkit-search-decoration { -webkit-appearance: none } ::-webkit-file-upload-button { -webkit-appearance: button; font: inherit } details, menu { display: block } summary { display: list-item } canvas { display: inline-block } template { display: none } [hidden] { display: none } body { font-size: 13px; line-height: 1.5 } .container { max-width: 728px; margin: 0 auto } a { text-decoration: none; color: #069 } a:hover, a:focus { text-decoration: underline } button { cursor: pointer } .small-header-icons { padding-right: .5em } .small-space-below { margin-bottom: .5em } img.block { display: block } h1, .h1 { font-size: 30px; font-size: 3rem } h2, .h2 { font-size: 24px; font-size: 2.4rem } h3, .h3 { font-size: 17px; font-size: 1.7rem } h4, .h4 { font-size: 14px; font-size: 1.4rem } .text-orange { color: #cc4b14 } .upper { text-transform: uppercase } .no-underline { text-decoration: none } cite { font-style: normal } ins { text-decoration: none } .hide { display: none; visibility: hidden } .show { display: block; visibility: visible } .show-inline { display: inline; visibility: visible } .clean-list { padding: 0; list-style: none } .number { list-style-type: decimal } .bullet { list-style-type: disc } .none { list-style-type: none } .ucletter { list-style-type: upper-alpha } .lcletter { list-style-type: lower-alpha } .ucroman { list-style-type: upper-roman } .lcroman { list-style-type: lower-roman } .inside { list-style-position: inside } .tighten-line-height { line-height: 1.25 } .credit { font-size: 10px } .inline-list > li, .inline-list > dt, .inline-list > dd { display: inline } .inline-group-item { display: inline-block; vertical-align: bottom } img { border: 0; max-width: 100%; height: auto; vertical-align: middle } .header-logo-container h1 { color: #fff; padding: 10px; background: #333 } .menu-button { border: 1px solid #ccc; padding: 10px 20px; float: right; margin: 5px 10px } button { font-family: Source Sans Pro, arial, helvetica, sans-serif } #menu { display: block; visibility: visible } .content { max-width: 728px; margin: 0 auto } .grade-c-hide { display: none } .grade-c-show { display: block; visibility: visible } .grade-c-invisible { visibility: hidden } .js .js-hide { display: none } #content { position: relative } .js-readcube-pdf { position: absolute; top: 0; right: 50% } .box-sizing { -webkit-box-sizing: border-box; -moz-box-sizing: border-box; box-sizing: border-box } .top-20 { top: 20px } .bottom-negative-20 { bottom: -20px } .flex-box { display: inline-block; display: -webkit-flex; display: flex } .flex-box-item { flex-grow: 1 } .flex-box-column { -webkit-flex-direction: column; flex-direction: column } .flex-box-column-item { flex: 1 1 auto } .flex-vertical-center { align-items: center; justify-content: center } .flex-space-between { justify-content: space-between } @media only screen and (max-width: 75em) { .mq1200-flex-box { display: inline-block; display: flex } .mq1200-flex-box-item { flex-grow: 1 } } @media only screen and (max-width: 54.688em) { .mq875-flex-box { display: inline-block; display: flex } .mq875-flex-box-item { flex-grow: 1 } .mq875-kill-flex-space-between { justify-content: flex-start } } @media only screen and (max-width: 40em) { .mq640-flex-box { display: inline-block; display: flex } .mq640-flex-box-item { flex-grow: 1 } } @media only screen and (max-width: 30em) { .mq480-flex-box { display: inline-block; display: flex } .mq480-flex-box-item { flex-grow: 1 } } .grid, .grid-ng { float: left; padding-left: 0 !important; padding-right: 0 !important } .grid-inline-wrapper { width: 100%; margin: 0; padding: 0; letter-spacing: -.31em } .grid-inline, .grid-inline-ng { display: inline-block; letter-spacing: .01em; vertical-align: top; padding-left: 0 !important; padding-right: 0 !important } .container { max-width: none; margin: 0; padding: 0 } .pin-right { float: right } .pin-left { float: left } .clear-float { float: none } .position-absolute { position: absolute } .position-relative { position: relative } .position-right { right: 0 } .block { display: block } .inline-block { display: inline-block } .inline { display: inline } .cover { width: 100%; height: 100%; margin: 0 !important; padding: 0 !important } .max-width { max-width: 100% } .full-width { width: 100% } .inline-group { font-size: 0 } .inline-group-item { display: inline-block; vertical-align: bottom } .inline-group-middle { vertical-align: middle } .inline-group-top { vertical-align: top } .parent-10 { z-index: 10 } .parent-9 { z-index: 9 } .parent-8 { z-index: 8 } .parent-7 { z-index: 7 } .parent-6 { z-index: 6 } .parent-5 { z-index: 5 } .parent-4 { z-index: 4 } .parent-3 { z-index: 3 } .parent-2 { z-index: 2 } .parent-1 { z-index: 1 } .cleared { zoom: 1 } .cleared:before, .cleared:after { content: ' '; display: table } .cleared:after { clear: both } .clear { clear: both } .clear-left { clear: left } .clear-right { clear: right } .hide, .grade-a-hide, .js .js-hide, .svg .js-svg-hide { display: none; visibility: hidden } .show, .js .js-show { display: block; visibility: visible } .show-inline, .js .js-show-inline { display: inline; visibility: visible } .visually-hidden, .js .js-visually-hidden { width: 1px; height: 1px; position: absolute !important; clip: rect(1px, 1px, 1px, 1px) } .invisible { visibility: hidden } .hide-text, .js .js-hide-text { display: block; text-indent: -9999em; direction: ltr; overflow: hidden } .hide-overflow { overflow: hidden } .text-left { text-align: left } .text-center { text-align: center } .text-right { text-align: right } .upper { text-transform: uppercase } .lower { text-transform: lowercase } .capitalize { text-transform: capitalize } .underline { text-decoration: underline; -webkit-text-decoration-skip: skip; text-decoration-skip-ink: auto } .double-underline { text-decoration: underline; -webkit-text-decoration-skip: skip; text-decoration-skip-ink: auto; border-bottom: 1px solid } .monospace { font-family: monospace } .nowrap { white-space: nowrap } .prewrap { word-wrap: break-word; white-space: pre-wrap } .overflow-ellipsis { -o-text-overflow: ellipsis; -ms-text-overflow: ellipsis; text-overflow: ellipsis } .unstyled { font-weight: 400; font-style: normal } .small-caps { font-size: .8em; text-transform: uppercase } .alert-wrapper { position: fixed; bottom: 0; left: 0; width: 100%; -webkit-transition: opacity .5s ease-out, bottom .5s ease-out; -moz-transition: opacity .5s ease-out, bottom .5s ease-out; transition: opacity .5s ease-out, bottom .5s ease-out } .alert-suppressed { bottom: -100px; opacity: 0 } .alert { position: relative; background-color: #999; border: 1px solid #666 } .alert-icon { background-size: 16px auto; background-position: top left } .alert-close-button, .alert-close-button:hover { position: absolute; top: 0; right: 0; width: 12px; height: 12px; border: none; background-color: transparent; background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxMiIgaGVpZ2h0PSIxMiIgdmlld0JveD0iMCAwIDEyIDEyIj48cGF0aCBmaWxsPSIjMDY5IiBkPSJNMS44IDEyTC4xIDEwLjMgMTAuMyAwIDEyIDEuNyAxLjggMTJ6bTEwLjEtMS43TDEwLjIgMTIgMCAxLjcgMS43IDBsMTAuMiAxMC4zeiIvPjwvc3ZnPg==), none } .alert-type-success { background-color: #e0f1d9; border-color: #090 } .alert-icon-success { background-image: url(data:image/svg+xml;base64,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), none } .alert-type-info { background-color: #daedf8; border-color: #215f90 } .alert-icon-info { background-image: url(data:image/svg+xml;base64,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), none } .alert-type-warning { background-color: #fcf1ba; border-color: #ab5306 } .alert-icon-warning { background-image: url(data:image/svg+xml;base64,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), none } .alert-type-error { background-color: #fcecec; border-color: #930721 } .alert-icon-error { background-image: url(data:image/svg+xml;base64,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), none } .search-btn { width: 4rem; min-width: 40px; height: 4rem; min-height: 40px; font-size: 1.2rem; background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxNiIgaGVpZ2h0PSIxNiIgdmlld0JveD0iMCAwIDE2IDE2Ij48cGF0aCBmaWxsPSIjZmZmIiBkPSJNMTAuNiAxLjNjMi4zIDAgNC4yIDEuOSA0LjIgNC4ycy0xLjkgNC4yLTQuMiA0LjItNC4yLTItNC4yLTQuMyAxLjktNC4xIDQuMi00LjFtMC0xLjNjLTMgMC01LjQgMi40LTUuNCA1LjRzMi40IDUuNCA1LjQgNS40IDUuNC0yLjQgNS40LTUuNC0yLjQtNS40LTUuNC01LjR6bS0zLjUgMTEuMWwtNC45IDQuOS0yLjItMi4yIDQuOS00LjggMi4yIDIuMXoiLz48L3N2Zz4=), none; background-size: 40% auto; background-color: #069; border: 1px solid #069; color: transparent } .search-btn:hover, .search-btn:focus { background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxNiIgaGVpZ2h0PSIxNiIgdmlld0JveD0iMCAwIDE2IDE2Ij48cGF0aCBmaWxsPSIjMDY5IiBkPSJNMTAuNiAxLjNjMi4zIDAgNC4yIDEuOSA0LjIgNC4ycy0xLjkgNC4yLTQuMiA0LjItNC4yLTItNC4yLTQuMyAxLjktNC4xIDQuMi00LjFtMC0xLjNjLTMgMC01LjQgMi40LTUuNCA1LjRzMi40IDUuNCA1LjQgNS40IDUuNC0yLjQgNS40LTUuNC0yLjQtNS40LTUuNC01LjR6bS0zLjUgMTEuMWwtNC45IDQuOS0yLjItMi4yIDQuOS00LjggMi4yIDIuMXoiLz48L3N2Zz4=), none; background-color: #fff } .search-input-box { margin-bottom: .4rem } .search-input-field input, .search-input-field input[type=search] { border: 1px solid transparent; outline: 0; padding: 0; width: 100%; background: none; font-size: 2.8rem; line-height: 1.25 } .search-input-btn { top: 0; right: 0; width: 4rem; min-width: 40px; height: 4rem; min-height: 40px; padding-left: 1rem; padding-bottom: 1px; background: #fff } .search-input-layout { margin-right: -12rem } .search-input-field { margin-right: 12rem } .search-input-suffix { width: 7rem; min-width: 70px } .search-input-suffix-inner { padding: .5rem 1px .5rem 5px; border-left: 1px solid #069 } .search-input-suffix select { width: 100% } .extend-suffix .search-input-layout { margin-right: -17rem } .extend-suffix .search-input-field { margin-right: 17rem } .extend-suffix .search-input-suffix { width: 12rem; min-width: 120px } @media only screen and (max-width: 40em) { .search-input-layout, .extend-suffix .search-input-layout { margin-right: 0 } .search-input-field, .extend-suffix .search-input-field { margin-right: 5rem } .search-input-suffix, .extend-suffix .search-input-suffix { position: absolute; right: 0; top: 5rem } .search-input-suffix-inner { border: 0 } .search-input-field input, .search-input-field input[type=search] { font-size: 2rem; line-height: 1.75 } } .ie9 .search-btn { background-size: 16px auto } @media screen and (-ms-high-contrast: active),(-ms-high-contrast: none) { .search-btn { background-size: 16px auto } } .search-input-field input::-webkit-input-placeholder { color: #999 } .search-input-field input:-moz-placeholder { color: #999; opacity: 1 } .search-input-field input::-moz-placeholder { color: #999; opacity: 1 } .search-input-field input:-ms-input-placeholder { color: #999 } html { height: 100%; overflow-y: scroll; font-size: 62.5% } body { min-height: 100%; font-family: Source Sans Pro, arial, helvetica, sans-serif; line-height: 1.76; color: #222; background: #eee; font-size: 1.7em; letter-spacing: .01em } figure { margin: 0 } body, div, dl, dt, dd, pre, code, form, fieldset, legend, input, button, textarea, p, blockquote, th, td { margin: 0; padding: 0 } h1, h2, h3, h4, h5, h6, small { margin: 0; padding: 0 } abbr[title] { text-decoration: none } .content { max-width: 1000px; margin: 0 auto } .article-page { background: #fff } .main-column { width: 60.2%; margin-right: 8.6% } .reading-companion { width: 31.2% } @media only screen and (max-width: 40em) { .main-column { width: 100%; margin-right: 0 } .reading-companion { display: none } } .z-index-100 { z-index: 100 } .z-index-50 { z-index: 50 } .z-index-2 { z-index: 2 } .z-index-1 { z-index: 1 } .top-20 { top: 20px } .top-negative-20 { top: -20px } .bottom-negative-20 { bottom: -20px } .max-width-160 { max-width: 160px } .min-width-0 { min-width: 0 } .min-width-0 { min-width: 0 } @media only screen and (min-width: 75.06em) { .full-size-width-160 { width: 160px } } @media only screen and (max-width: 30em) { .mq480-max-width-100 { max-width: 100px } } .separator { margin-top: 0; position: relative; border: none; border-top: 1px solid #999 } .separator-light { border-color: #eee } .composite-layer { -webkit-transform: translateZ(0); -moz-transform: translateZ(0); transform: translateZ(0) } @media only screen and (max-width: 75em) { .mq1200-kill-flex { display: block } } @media only screen and (max-width: 54.688em) { .mq875-kill-flex { display: block } } @media only screen and (max-width: 40em) { .mq640-kill-flex { display: block } } @media only screen and (max-width: 30em) { .mq480-kill-flex { display: block } } .grid-inline, .grid { margin-right: 3.2% } .last { margin-right: 0 } .grid-1 { width: 5.4% } .grid-2 { width: 14% } .grid-3 { width: 22.6% } .grid-4 { width: 31.2% } .grid-5 { width: 39.8% } .grid-6 { width: 48.4% } .grid-7 { width: 57% } .grid-8 { width: 65.6% } .grid-9 { width: 74.2% } .grid-10 { width: 82.8% } .grid-11 { width: 91.4% } .grid-12 { width: 100% } .grid-left-1 { margin-left: 8.6% } .grid-right-1 { margin-right: 8.6% } .grid-left-2 { margin-left: 17.2% } .grid-right-2 { margin-right: 17.2% } .grid-left-3 { margin-left: 25.8% } .grid-right-3 { margin-right: 25.8% } .grid-left-4 { margin-left: 34.4% } .grid-right-4 { margin-right: 34.4% } .grid-left-5 { margin-left: 43% } .grid-right-5 { margin-right: 43% } .grid-left-6 { margin-left: 51.6% } .grid-right-6 { margin-right: 51.6% } .grid-left-7 { margin-left: 60.2% } .grid-right-7 { margin-right: 60.2% } .grid-left-8 { margin-left: 68.8% } .grid-right-8 { margin-right: 68.8% } .grid-left-9 { margin-left: 77.4% } .grid-right-9 { margin-right: 77.4% } .grid-left-10 { margin-left: 86% } .grid-right-10 { margin-right: 86% } .grid-left-11 { margin-left: 94.6% } .grid-right-11 { margin-right: 94.6% } .grid-1of4 { width: 25% } .grid-1of3 { width: 33.3334%; width: calc(100% / 3) } .grid-1of2 { width: 50% } .grid-3of4 { width: 75% } .grid-1of5 { width: 20% } .grid-2of5 { width: 40% } .grid-3of5 { width: 60% } .grid-4of5 { width: 80% } .grid-split-margin-left { margin-left: 1.6%; padding-left: 1.6% !important } .grid-split-margin-right { margin-right: 1.6%; padding-right: 1.6% !important } p, ul, ol { margin-top: 0; margin-bottom: 28px } .standard-space-below { margin-bottom: 28px } .small-space-below { margin-bottom: 14px } .tiny-space-below { margin-bottom: 7px } .standard-space-above { margin-top: 28px } .small-space-above { margin-top: 14px } .tiny-space-above { margin-top: 7px } .standard-space-around { margin: 28px } .suppress-bottom-margin > * { margin-bottom: 0 } .add-top-margin > * + * { margin-top: 28px } .add-top-margin-small > * + * { margin-top: 14px } .h4 { color: #666; font-family: Source Sans Pro, arial, helvetica, sans-serif; font-weight: 700; text-transform: uppercase; -webkit-font-smoothing: antialiased; -moz-osx-font-smoothing: grayscale } h5, .h5 { font-size: 1.2rem } h1, .h1, h2, .h2, h3, .h3, h5, .h5 { font-family: Lora, Palatino, Times, Times New Roman, serif; font-weight: 400 } .serif { font-family: Lora, Palatino, Times, Times New Roman, serif } .wf-loading h1, .wf-loading .h1, .wf-loading h2, .wf-loading .h2, .wf-loading h3, .wf-loading .h3, .wf-loading h5, .wf-loading .h5, .wf-loading .serif { font-family: Palatino, Times, Times New Roman, serif } .wf-active .serif, .wf-active h1, .wf-active .h1, .wf-active h2, .wf-active .h2, .wf-active h3, .wf-active .h3, .wf-active h5, .wf-active .h5 { font-family: Lora, Palatino, Times, Times New Roman, serif } .sans-serif, .wf-active .sans-serif, .wf-active .h4 { font-family: Source Sans Pro, arial, helvetica, sans-serif } .sans-ultra-light, .wf-active .sans-ultra-light { font-family: Helvetica Neue, Helvetica, Arial, sans-serif; color: #666; font-weight: 100; -webkit-font-smoothing: antialiased; -moz-osx-font-smoothing: grayscale } .strong { font-weight: 700; -webkit-font-smoothing: antialiased; -moz-osx-font-smoothing: grayscale } .emphasis { font-style: italic } .contrast-text, .contrast-text a { color: #fff } .text-blue { color: #069 } .text-gray { color: #222 } .text-gray-light { color: #666 } .highlight { background-color: #ff9 } .equalize-line-height { line-height: 1em } .extra-tight-line-height { line-height: 1.3 } .tighten-line-height { line-height: 1.4 } .doctype-line-height { line-height: 24px } .text11 { font-size: 1.1rem } .text13 { font-size: 1.3rem } .text14 { font-size: 1.4rem } .text15 { font-size: 1.5rem } .text17 { font-size: 1.7rem } .text18 { font-size: 1.8rem } .text24 { font-size: 2.4rem } .text30 { font-size: 3rem } .text48 { font-size: 4.8rem } .v-middle { vertical-align: middle } .v-top { vertical-align: top } @font-face { font-family: npg-stix-regular; src: url(/static/fonts/npg-stix-regular.eot); src: url(/static/fonts/npg-stix-regular.eot?#iefix) format("embedded-opentype"), url(/static/fonts/npg-stix-regular.woff) format("woff"), url(/static/fonts/npg-stix-regular.ttf) format("truetype"), url(/static/fonts/npg-stix-regular.svg#npg-stix-regular) format("svg") } .stix { font-family: npg-stix-regular } fieldset { border: 0 } .txt, input[type=search].txt { border: 1px solid #999; background: #fff; color: #222; padding: 10px; line-height: 1.25; box-sizing: border-box; -webkit-transition: background-color .3s ease-in; -moz-transition: background-color .3s ease-in; transition: background-color .3s ease-in } input[type=search].txt { outline-offset: -2px } .txt:focus, input[type=search].txt:focus { outline: 1px solid #dadada } .txt:disabled { background: #eee } .input-placeholder { color: #aaa } .error-message { background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxOCIgaGVpZ2h0PSIxNiIgdmlld0JveD0iMCAwIDE2IDE2Ij48cGF0aCBmaWxsPSIjOTMwNzIxIiBkPSJNMTUuNSAxNC4xbC03LTEyLjNjLS4zLS41LS43LS41LTEgMGwtNyAxMi4zYy0uMy41IDAgLjkuNS45aDE0Yy41IDAgLjgtLjQuNS0uOXpNNy4zIDVoMS40Yy4yIDAgLjMuMS4zLjNsLS4yIDUuNWMwIC4yLS4xLjMtLjMuM2gtMWMtLjIgMC0uMy0uMS0uMy0uM0w3IDUuM2MwLS4yLjEtLjMuMy0uM3ptLjcgOWMtMSAwLTEuMS0uNS0xLjEtMSAwLS42LjItMSAxLjEtMSAuOSAwIDEuMS40IDEuMSAxIDAgLjUtLjIgMS0xLjEgMXoiLz48L3N2Zz4=), none; background-size: 18px 16px; background-position: 0 50%; background-repeat: no-repeat; color: #b12206; display: block; font-size: 1.3rem; padding-left: 25px; margin-top: 10px } .error-message a { color: inherit; text-decoration: underline; -webkit-text-decoration-skip: skip; text-decoration-skip-ink: auto } input + label { padding-left: .5em } .background-white { background-color: #fff } .background-gray-dark { background-color: #333 } .background-gray-medium { background-color: #dadada } .background-bluegray { background-color: #5a5a62 } .background-bluegray-translucent { background-color: #5a5a62; background-color: rgba(90, 90, 98, .8) } [data-hellip] { max-height: 12.5rem; overflow: hidden } @media only screen and (max-width: 54.688em) { [data-hellip] { max-height: 15rem; overflow: hidden } } .ma0 { margin: 0 } .ma1 { margin: 1px } .ma2 { margin: 2px } .ma4 { margin: 4px } .ma6 { margin: 6px } .ma10 { margin: 10px } .ma15 { margin: 15px } .ma20 { margin: 20px } .ma30 { margin: 30px } .ma40 { margin: 40px } .ma50 { margin: 50px } .ma70 { margin: 70px } .mt0 { margin-top: 0 } .mt1 { margin-top: 1px } .mt2 { margin-top: 2px } .mt4 { margin-top: 4px } .mt6 { margin-top: 6px } .mt10 { margin-top: 10px } .mt15 { margin-top: 15px } .mt20 { margin-top: 20px } .mt30 { margin-top: 30px } .mt40 { margin-top: 40px } .mt50 { margin-top: 50px } .mt70 { margin-top: 70px } .mr0 { margin-right: 0 } .mr1 { margin-right: 1px } .mr2 { margin-right: 2px } .mr4 { margin-right: 4px } .mr6 { margin-right: 6px } .mr10 { margin-right: 10px } .mr15 { margin-right: 15px } .mr20 { margin-right: 20px } .mr30 { margin-right: 30px } .mr40 { margin-right: 40px } .mr50 { margin-right: 50px } .mr70 { margin-right: 70px } .mb0 { margin-bottom: 0 } .mb1 { margin-bottom: 1px } .mb2 { margin-bottom: 2px } .mb4 { margin-bottom: 4px } .mb6 { margin-bottom: 6px } .mb10 { margin-bottom: 10px } .mb15 { margin-bottom: 15px } .mb20 { margin-bottom: 20px } .mb30 { margin-bottom: 30px } .mb40 { margin-bottom: 40px } .mb50 { margin-bottom: 50px } .mb70 { margin-bottom: 70px } .mb120 { margin-bottom: 120px } .ml0 { margin-left: 0 } .ml1 { margin-left: 1px } .ml2 { margin-left: 2px } .ml4 { margin-left: 4px } .ml6 { margin-left: 6px } .ml10 { margin-left: 10px } .ml15 { margin-left: 15px } .ml20 { margin-left: 20px } .ml30 { margin-left: 30px } .ml40 { margin-left: 40px } .ml70 { margin-left: 70px } .mli { margin-left: .5em } .mri { margin-right: .5em } .mt-grid-match { margin-top: 3.2% } .mr-grid-match { margin-right: 3.2% } .mb-grid-match { margin-bottom: 3.2% } .ml-grid-match { margin-left: 3.2% } .ma-grid-match { margin: 3.2% } .mt-negative-20 { margin-top: -20px } .mt-negative-30 { margin-top: -30px } .pa0 { padding: 0 } .pa1 { padding: 1px } .pa2 { padding: 2px } .pa4 { padding: 4px } .pa6 { padding: 6px } .pa10 { padding: 10px } .pa15 { padding: 15px } .pa20 { padding: 20px } .pa30 { padding: 30px } .pa40 { padding: 40px } .pa70 { padding: 70px } .pt0 { padding-top: 0 } .pt1 { padding-top: 1px } .pt2 { padding-top: 2px } .pt4 { padding-top: 4px } .pt6 { padding-top: 6px } .pt10 { padding-top: 10px } .pt15 { padding-top: 15px } .pt20 { padding-top: 20px } .pt30 { padding-top: 30px } .pt40 { padding-top: 40px } .pt70 { padding-top: 70px } .pr0 { padding-right: 0 } .pr1 { padding-right: 1px } .pr2 { padding-right: 2px } .pr4 { padding-right: 4px } .pr6 { padding-right: 6px } .pr10 { padding-right: 10px } .pr15 { padding-right: 15px } .pr20 { padding-right: 20px } .pr30 { padding-right: 30px } .pr40 { padding-right: 40px } .pr70 { padding-right: 70px } .pb0 { padding-bottom: 0 } .pb1 { padding-bottom: 1px } .pb2 { padding-bottom: 2px } .pb4 { padding-bottom: 4px } .pb6 { padding-bottom: 6px } .pb10 { padding-bottom: 10px } .pb15 { padding-bottom: 15px } .pb20 { padding-bottom: 20px } .pb30 { padding-bottom: 30px } .pb40 { padding-bottom: 40px } .pb70 { padding-bottom: 70px } .pl0 { padding-left: 0 } .pl1 { padding-left: 1px } .pl2 { padding-left: 2px } .pl4 { padding-left: 4px } .pl6 { padding-left: 6px } .pl10 { padding-left: 10px } .pl15 { padding-left: 15px } .pl20 { padding-left: 20px } .pl30 { padding-left: 30px } .pl40 { padding-left: 40px } .pl70 { padding-left: 70px } @media only screen and (max-width: 75em) { .mq1200-padded { padding-left: 20px; padding-right: 20px } } @media only screen and (max-width: 75em) { .mq1200-pl0 { padding-left: 0 } .mq1200-pl20 { padding-left: 20px } } @media only screen and (max-width: 54.688em) { .mq875-ml0 { margin-left: 0 } .mq875-mb20 { margin-bottom: 20px } .mq875-mt30 { margin-top: 30px } .mq875-pa0 { padding: 0 } .mq875-pl0 { padding-left: 0 } .mq875-pl20 { padding-left: 20px } .mq875-pr20 { padding-right: 20px } } @media only screen and (max-width: 40em) { .mq640-pa4 { padding: 4px } .mq640-pt10 { padding-top: 10px } .mq640-pb10 { padding-bottom: 10px } .mq640-pt20 { padding-top: 20px } .mq640-pl20 { padding-left: 20px } .mq640-pl0 { padding-left: 0 } .mq640-pr5 { padding-right: 5px } .mq640-pr20 { padding-right: 20px } .mq640-pb30 { padding-bottom: 30px } .mq640-mt0 { margin-top: 0 } .mq640-ml0 { margin-left: 0 } .mq640-mb0 { margin-bottom: 0 } .mq640-mb5 { margin-bottom: 5px } .mq640-mt20 { margin-top: 20px } .mq640-mb20 { margin-bottom: 20px } .mq640-mb30 { margin-bottom: 30px } } @media only screen and (max-width: 30em) { .mq480-mr0 { margin-right: 0 } .mq480-mb10 { margin-bottom: 10px } .mq480-pt10 { padding-top: 10px } } .table { display: table } .table-row { display: table-row } .table-cell { display: table-cell } @media only screen and (max-width: 75em) { .mq1200-block { display: block } } @media only screen and (max-width: 54.688em) { .mq875-block { display: block } } @media only screen and (max-width: 40em) { .mq640-block { display: block } } @media only screen and (max-width: 30em) { .mq480-block { display: block } } .js .js-author-etal { display: none; visibility: hidden } .js .js-authors-expanded .js-author-etal { display: inline; visibility: visible } @media only screen and (max-width: 75em) { .mq1200-hide, .js .js-mq1200-hide { display: none; visibility: hidden } .mq1200-show, .js .js-mq1200-show { display: block; visibility: visible } .mq1200-show-inline, .js .js-mq1200-show-inline { display: inline; visibility: visible } .mq1200-visually-show { clip: auto; height: auto; position: static !important; width: auto } } @media only screen and (max-width: 54.688em) { .mq875-hide, .js .js-mq875-hide { display: none; visibility: hidden } .mq875-show, .js .js-mq875-show { display: block; visibility: visible } .mq875-show-inline, .js .js-mq875-show-inline { display: inline; visibility: visible } .mq875-visually-show { clip: auto; height: auto; position: static !important; width: auto } } @media only screen and (max-width: 40em) { .mq640-hide, .js .js-mq640-hide { display: none; visibility: hidden } .mq640-show, .js .js-mq640-show { display: block; visibility: visible } .mq640-show-inline, .js .js-mq640-show-inline { display: inline; visibility: visible } .mq640-visually-show { clip: auto; height: auto; position: static !important; width: auto } } @media only screen and (max-width: 30em) { .mq480-hide, .js .js-mq480-hide { display: none; visibility: hidden } .mq480-show, .js .js-mq480-show { display: block; visibility: visible } .mq480-show-inline, .js .js-mq480-show-inline { display: inline; visibility: visible } .mq480-visually-show { clip: auto; height: auto; position: static !important; width: auto } .js .js-smaller-author-etal { display: none; visibility: hidden } .js .js-authors-expanded .js-smaller-author-etal { display: inline; visibility: visible } } .container-type-hero:first-child .hero { top: -100px; margin-bottom: -100px; position: relative } .container-type-hero + .container-type-article-grid, .container-type-hero + .container-type-mixed-grid { margin-top: -30px } .container-type-hero + .container-type-article-grid .article-grid-heading, .container-type-hero + .container-type-mixed-grid .mixed-grid-heading { width: 1px; height: 1px; position: absolute !important; clip: rect(1px, 1px, 1px, 1px) } .hero { display: block; overflow: hidden; position: relative; background-color: #333; text-decoration: none } .hero-spacer { margin-bottom: 30px } .hero-image-wrapper { width: 5000px; margin-left: -2500px; left: 50%; height: 100%; position: absolute; text-align: center } .hero-image { height: 100% } .hero-content { position: relative; padding-top: 130px; min-height: 200px } .hero-image-credit { position: absolute; bottom: 0; right: 10px } .hero-text-wrapper { padding-top: 30px; padding-bottom: 30px } .hero-title { font-size: 3rem; line-height: 1.2; font-weight: 400; -webkit-font-smoothing: antialiased } a.hero:hover .hero-title-inner { box-shadow: inset 0 -1px 0 0 #fff } .hero-summary { font-size: 1.4rem; -webkit-font-smoothing: antialiased } .hero-article-meta { margin-bottom: 10px; font-size: 1.3rem } @media only screen and (max-width: 54.688em) { .hero-image-credit { right: 0 } .hero-content { position: relative; padding-top: 10px; min-height: 120px } .hero-text-wrapper { padding-top: 20px; padding-bottom: 20px } .hero-title { font-size: 2.4rem } .hero-title, .hero-summary { -webkit-font-smoothing: auto } .hero-image { height: 130% } } @media only screen and (max-width: 40em) { .hero-content { position: relative; padding-top: 10px; min-height: 90px } .hero-text-wrapper { padding-top: 15px; padding-bottom: 15px } .hero-title { font-size: 1.6rem } .hero-summary { font-size: 1.2rem } .hero-article-meta { margin-bottom: 5px; font-size: 1.1rem } .hero-image { height: 150% } } .advert img, .advert object, .advert embed { max-width: 100% } .leaderboard-container { background-color: #44444e; text-align: center } @media only screen and (min-width: 728px) { .leaderboard-container { height: 90px } } @media only screen and (max-width: 728px) { .billboard-container { max-height: 60px } } @media only screen and (min-width: 950px) { .billboard-container { max-height: 250px } } .billboard-container { max-width: 970px; max-height: 250px; margin: 0 auto; overflow: hidden } @media only screen and (max-width: 960px) { .billboard-container { max-width: 728px; max-height: 90px } } .leaderboard-inner { max-width: 728px; max-height: 90px; margin: 0 auto; overflow: hidden; padding: 0 14px; position: relative } .leaderboard-inner:before, .leaderboard-inner:after { content: 'Advertisement'; color: #fff; background: #999; font-size: 9px; width: 90px; line-height: 10px; font-family: arial, sans-serif; text-transform: uppercase; position: absolute; top: 90px; -webkit-transform: rotate(90deg); -ms-transform: rotate(90deg); transform: rotate(90deg); -webkit-transform-origin: top right; -ms-transform-origin: top right; transform-origin: top right } .leaderboard-inner:before { padding: 1px 0 2px; border-top: 1px solid #fff; left: -76px } .leaderboard-inner:after { padding: 2px 0 1px; border-bottom: 1px solid #fff; right: 0 } @media only screen and (max-width: 756px) { .leaderboard-inner { padding: 0 } .leaderboard-inner:before, .leaderboard-inner:after { display: none } } .billboard-container img, .billboard-container object, .billboard-container embed, .billboard-inner iframe { max-height: 250px } .leaderboard-container img, .leaderboard-container object, .leaderboard-container embed, .leaderboard-container iframe { max-height: 90px } .medium-rectangle object, .medium-rectangle embed, .medium-rectangle iframe { max-height: 250px } .skyscraper img, .skyscraper object, .skyscraper embed, .skyscraper iframe, .skyscraper a { display: block; margin: 0 auto } @media only screen and (max-width: 45.75em) { .leaderboard-container object, .leaderboard-container embed { display: none } .billboard-container object, .leaderboard-container embed { display: none } } .icon { background-repeat: no-repeat } .icon-left { background-position: 0 50% } .icon-right { background-position: 100% 50% } .icon-right-top { background-position: 100% 0 } .icon-above { background-position: 50% 0; padding-top: 25px; min-width: 25px } .icon-center { background-position: 50% 50% } .icon-rotate:after { content: ''; position: absolute; background-repeat: no-repeat; background-position: 0 0; top: 50%; right: 0; -webkit-transform: translateY(-50%); -ms-transform: translateY(-50%); transform: translateY(-50%); -webkit-transition-duration: .2s; transition-duration: .2s } .js-icon-toggle.icon-rotate:after { -webkit-transform: rotate(180deg) translateY(50%); -ms-transform: rotate(180deg) translateY(50%); transform: rotate(180deg) translateY(50%) } a.small-header-icons.tray-button-active, a.small-header-icons:hover { background-color: #fff } .icon-login-25x25-white { background-image: url(data:image/svg+xml;base64,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), none; background-size: 25px auto } a.small-header-icons:hover .icon-login-25x25-gray { background-image: url(data:image/svg+xml;base64,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), none; color: #5a5a62 } .icon-search-25x25-white { background-image: url(data:image/svg+xml;base64,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), none; background-size: 25px auto } a.small-header-icons.tray-button-active .icon-search-25x25-gray, a.small-header-icons:hover .icon-search-25x25-gray { background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIyNSIgaGVpZ2h0PSIyNSIgdmlld0JveD0iMCAwIDI1IDI1Ij48cGF0aCBmaWxsPSIjNUE1QTYyIiBkPSJNMTYuNTgzIDJjMy41ODMgMCA2LjU4MyAzIDYuNTgzIDYuNTgzcy0zIDYuNTgzLTYuNTgzIDYuNTgzUzEwIDEyLjE2NiAxMCA4LjU4MyAxMyAyIDE2LjU4MyAybTAtMmMtNC42NjcgMC04LjQxNyAzLjc1LTguNDE3IDguNDE3czMuNzUgOC40MTcgOC40MTcgOC40MTdTMjUgMTMuMTY3IDI1IDguNDE3IDIxLjI1IDAgMTYuNTgzIDB6bS01LjUgMTcuMzMzTDMuNDE3IDI1IDAgMjEuNTgzbDcuNjY3LTcuNjY2IDMuNDE2IDMuNDE2eiIvPjwvc3ZnPg==), none; color: #5a5a62 } .icon-submit-25x25-white { background-image: url(data:image/svg+xml;base64,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), none; background-size: 25px auto } a.small-header-icons:hover .icon-submit-25x25-gray { background-image: url(data:image/svg+xml;base64,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), none; color: #5a5a62 } .icon-ealert-25x25-white { background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIyNSIgaGVpZ2h0PSIyNSIgdmlld0JveD0iMCAwIDI1IDI1Ij48cGF0aCBmaWxsPSIjZmZmIiBkPSJNMjUgMy4xaC0yNXYxOC44aDI1di0xOC44em0tMTcuOCAxMi44bC0zLjkgNC40Yy0uMi4yLS41LjMtLjYuMy0uMiAwLS41LS4yLS42LS4zLS4zLS4zLS4zLS45IDAtMS40bDMuOS00LjRjLjMtLjMuOS0uMyAxLjMgMCAuMi41LjIgMS4xLS4xIDEuNHptNS4zLS45Yy0uMiAwLS4zIDAtLjUtLjJsLTkuOC04LjljLS41LS4zLS41LS43LS4yLTEuMS4zLS41LjgtLjUgMS4xLS4ybDkuNCA4LjQgOS40LTguNGMuMy0uMy44LS4zIDEuMS4yLjMuMy4zLjktLjIgMS4xbC05LjcgOC45Yy0uMS4yLS40LjItLjYuMnptMTAuNSA1LjNjLS4yLjItLjUuMy0uNi4zcy0uNS0uMi0uNi0uM2wtNC4xLTQuNGMtLjMtLjMtLjMtLjkgMC0xLjQuMy0uMy45LS4zIDEuMyAwbDQuMSA0LjRjLjIuNS4yIDEuMS0uMSAxLjR6Ii8+PC9zdmc+), none; background-size: 25px auto } a.small-header-icons:hover .icon-ealert-25x25-gray { background-image: url(data:image/svg+xml;base64,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), none; color: #5a5a62 } .icon-arrow-down-12x7-gray, .icon-rotate.icon-arrow-down-12x7-gray:after, .tools-menu-button-icon, .icon-rotate.tools-menu-button-icon:after { background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxMiIgaGVpZ2h0PSI3IiB2aWV3Qm94PSIwIDAgMTIgNyI+PHBhdGggZmlsbD0iIzY4Njk2OSIgZD0iTTkuNyAwbC0zLjcgNC4zLTMuNy00LjNoLTIuM2w2IDcgNi03aC0yLjN6Ii8+PC9zdmc+), none; background-size: 12px auto } .icon-rotate.icon-arrow-down-12x7-gray, .icon-rotate.icon-arrow-up-12x7-gray, .icon-rotate.icon-arrow-down-12x7-white, .icon-rotate.icon-arrow-up-12x7-white, .icon-rotate.icon-arrow-down-12x7-blue, .icon-rotate.icon-arrow-up-12x7-blue, .icon-rotate.tools-menu-button-icon { background-image: none } .icon-rotate.icon-arrow-down-12x7-gray:after, .icon-rotate.icon-arrow-up-12x7-gray:after, .icon-rotate.icon-arrow-down-12x7-white:after, .icon-rotate.icon-arrow-up-12x7-white:after, .icon-rotate.icon-arrow-down-12x7-blue:after, .icon-rotate.icon-arrow-up-12x7-blue:after, .icon-rotate.tools-menu-button-icon:after { width: 12px; height: 7px } a { text-decoration: none; vertical-align: baseline; color: #069 } a:hover, a:focus { text-decoration: underline; -webkit-text-decoration-skip: skip; text-decoration-skip-ink: auto } .block-link:hover > span, .block-link:focus > span { text-decoration: underline; -webkit-text-decoration-skip: skip; text-decoration-skip-ink: auto } .header-tools-link { height: 29px } .banner .active-tools-link { background-color: #fff; color: #222 } .background-brand-secondary .tools-popup a { color: #069 } .small-header-icons, .general-button, .horizontal-nav-button, .pill-button, .search-btn { -webkit-transition: background-color .2s ease-out, color .2s ease-out; -moz-transition: background-color .2s ease-out, color .2s ease-out; -o-transition: background-color .2s ease-out, color .2s ease-out; transition: background-color .2s ease-out, color .2s ease-out } .pill-button > span { padding-right: 20px; background-repeat: no-repeat; background-position: 100% 50%; background-size: 10px auto; background-image: url(data:image/svg+xml;base64,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), none } .pill-button:hover > span { background-image: url(data:image/svg+xml;base64,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), none } .pill-button-expand > span:after { width: 12px; height: 7px; background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxMiIgaGVpZ2h0PSI3IiB2aWV3Qm94PSIwIDAgMTIgNyI+PHBhdGggZmlsbD0iIzA2OSIgZD0iTTkuNiAwbC0zLjYgNC4zLTMuNi00LjNoLTIuNGw2IDcgNi03aC0yLjR6Ii8+PC9zdmc+), none } .pill-button-expand:hover > span:after { background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxMiIgaGVpZ2h0PSI3IiB2aWV3Qm94PSIwIDAgMTIgNyI+PHBhdGggZmlsbD0iI2ZmZiIgZD0iTTkuNiAwbC0zLjYgNC4zLTMuNi00LjNoLTIuNGw2IDcgNi03aC0yLjR6Ii8+PC9zdmc+), none } .horizontal-nav-button > span { background-repeat: no-repeat; background-size: 40px 35px; display: inline-block; vertical-align: middle } .horizontal-nav-button.left > span { background-image: url(data:image/svg+xml;base64,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), none; background-position: left; padding-left: 55px } .horizontal-nav-button.right > span { background-image: url(data:image/svg+xml;base64,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), none; background-position: right; padding-right: 55px } .horizontal-nav-button.left:hover > span { background-image: url(data:image/svg+xml;base64,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), none } .horizontal-nav-button.right:hover > span { background-image: url(data:image/svg+xml;base64,PD94bWwgdmVyc2lvbj0iMS4wIiBlbmNvZGluZz0idXRmLTgiPz48IS0tIEdlbmVyYXRvcjogQWRvYmUgSWxsdXN0cmF0b3IgMTguMC4wLCBTVkcgRXhwb3J0IFBsdWctSW4gLiBTVkcgVmVyc2lvbjogNi4wMCBCdWlsZCAwKS0tPjwhRE9DVFlQRSBzdmcgUFVCTElDICItLy9XM0MvL0RURCBTVkcgMS4xLy9FTiIgImh0dHA6Ly93d3cudzMub3JnL0dyYXBoaWNzL1NWRy8xLjEvRFREL3N2ZzExLmR0ZCI+PHN2ZyB2ZXJzaW9uPSIxLjEiIGlkPSJMYXllcl8yIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHhtbG5zOnhsaW5rPSJodHRwOi8vd3d3LnczLm9yZy8xOTk5L3hsaW5rIiB4PSIwcHgiIHk9IjBweCIgdmlld0JveD0iMjg2LjEgMTA3LjQgMzkxLjkgMzM1IiBlbmFibGUtYmFja2dyb3VuZD0ibmV3IDI4Ni4xIDEwNy40IDM5MS45IDMzNSIgeG1sOnNwYWNlPSJwcmVzZXJ2ZSI+PHBvbHlnb24gZmlsbD0iIzAwNjY5OSIgcG9pbnRzPSIyODYuMSwzNjUuMyAyODYuMSw0NDIuNSA1MTUuNiwyNzQuOSAyODYuMSwxMDcuNCAyODYuMSwxODQuNiA0MDkuOSwyNzQuOSIvPjxwb2x5Z29uIGZpbGw9IiMwMDY2OTkiIHBvaW50cz0iNDQ4LjUsMzY1LjMgNDQ4LjUsNDQyLjUgNjc4LDI3NC45IDQ0OC41LDEwNy40IDQ0OC41LDE4NC42IDU3Mi40LDI3NC45Ii8+PC9zdmc+Cg==), none } @media only screen and (max-width: 40em) { .horizontal-nav-button { min-width: 0 } .horizontal-nav-button > span { height: 40px; overflow: hidden; width: 0 } .horizontal-nav-button.left > span { padding-left: 40px } .horizontal-nav-button.right > span { padding-left: 40px; padding-right: 0 } } .button-match-form { padding: 10px 25px; min-width: 0 } .tab-like button { color: #069; border: solid #069; border-width: 1px 1px 1px 0; background-color: #dae5ea; position: relative; width: 100% } .tab-like:first-child button { border-left: 1px solid #069 } .tab-like button:focus { text-decoration: none; outline: thin dotted } .tab-like button.selected { color: #222; background-color: #fff; border-bottom: 1px solid #fff; font-weight: 700; -webkit-font-smoothing: antialiased; -moz-osx-font-smoothing: grayscale } .tab-like:first-child button:before, .tab-like button.selected:after { content: ''; width: 1px; height: 1px; background-color: #069; position: absolute; bottom: -1px; right: -1px } .tab-like:first-child button:before { left: -1px } .number { list-style-type: decimal } .bullet { list-style-type: disc } .none { list-style-type: none } .ucletter { list-style-type: upper-alpha } .lcletter { list-style-type: lower-alpha } .ucroman { list-style-type: upper-roman } .lcroman { list-style-type: lower-roman } .inside { list-style-position: inside } .clean-list { padding: 0; list-style: none } nav ul, nav ol { list-style: none; list-style-image: none } .ie11-list-hack { list-style-image: url(data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7) } .horizontal-list > li { float: left } .inline-list > li, .inline-list > dt, .inline-list > dd { display: inline } .piped-list > li { padding: 0 8px; border-left: 1px solid #dadada } .piped-list > li:first-child { border: 0; padding-left: 0 } .indented-list p, .indented-list ul, .indented-list h1, .indented-list h3 { margin-left: 50px } table { width: 100%; margin-bottom: 0; border-collapse: collapse; border-spacing: 0 } .table-group > table { border-bottom: 1px solid #dadada } .table-group > .last-table { border-bottom: 0 } .table-group > table + table { margin-top: 24px; border-top: 1px solid #dadada } th, td { padding: 5px 10px; border-right: 1px solid #dadada; text-align: left } .match-spacing { padding: 5px 10px } th { vertical-align: bottom } th[valign=top], .row-scope { vertical-align: top } th[valign=middle] { vertical-align: middle } td { vertical-align: top } .table-highlight tr:hover, .table-highlight tr:hover th, .table-highlight tr:hover td { background-color: #ff9 } .last-cell { border-right: 0 } thead tr { border-bottom: 1px solid #dadada } tbody tr { border-top: 1px solid #dadada } tbody tr:first-child { border-top: 0 } th, tr { background: #eee } .odd { background: #fff } tfoot tr { border-top: 2px solid #dadada } tfoot td { font-weight: 700; -webkit-font-smoothing: antialiased; -moz-osx-font-smoothing: grayscale } .js .tab-single + .tab-content > div { border: 0; padding: 0 } .image-constraint-stretch img { max-width: none; max-height: none; width: 25% } @media only screen and (min-width: 75.06em) { .full-size-last { margin-right: 0 } .full-size-clear { clear: both } .full-size-kill-left { margin-left: 0 } } @media only screen and (max-width: 75em) and (min-width: 54.74em) { .just-mq1200-last { margin-right: 0 } .just-mq1200-clear { clear: both } .just-mq1200-kill-left { margin-left: 0 } } @media only screen and (max-width: 54.688em) and (min-width: 40.06em) { .just-mq875-last { margin-right: 0 } .just-mq875-clear { clear: both } .just-mq875-kill-left { margin-left: 0 } } @media only screen and (max-width: 40em) and (min-width: 30.06em) { .just-mq640-last { margin-right: 0 } .just-mq640-clear { clear: both } .just-mq640-kill-left { margin-left: 0 } } @media only screen and (max-width: 30em) { .just-mq480-last { margin-right: 0 } .just-mq480-clear { clear: both } .just-mq480-kill-left { margin-left: 0 } } @media only screen and (max-width: 75em) { .mq1200-grid-12 { width: 100% } .mq1200-grid-4 { width: 31.2% } } @media only screen and (max-width: 54.688em) { .mq875-grid-12 { width: 100% } .mq875-grid-10 { width: 82.8% } .mq875-grid-8 { width: 65.6% } .mq875-grid-7 { width: 57% } .mq875-grid-6 { width: 48.4% } .mq875-grid-4 { width: 31.2% } .mq875-grid-3 { width: 22.6% } .mq875-grid-1 { width: 5.4% } .mq875-kill-left { margin-left: 0 } } @media only screen and (max-width: 40em) { .mq640-last { margin-right: 0 } .mq640-clear { clear: both } .mq640-grid-12 { width: 100% } .mq640-grid-9 { width: 74.2% } .mq640-grid-6 { width: 48.4% } .mq640-grid-4 { width: 31.2% } .mq640-kill-left { margin-left: 0 } } @media only screen and (max-width: 30em) { .mq480-grid-12 { width: 100% } } body:before { content: 'full'; position: absolute; top: -1px; left: -1px; height: 0; width: 0; overflow: hidden } @media only screen and (max-width: 75em) { body:before { content: 'mq1200' } } @media only screen and (max-width: 54.688em) { body:before { content: 'mq875' } } @media only screen and (max-width: 40em) { body:before { content: 'mq640' } } @media only screen and (max-width: 30em) { body:before { content: 'mq480' } } .skiplink { width: 0; height: 0; display: block; overflow: hidden } .skiplink:focus { width: auto; height: auto; overflow: visible; margin: 2px 0 1px; padding: 2px } .breadcrumbs { padding: 10px 20px } .breadcrumbs ol { overflow: hidden; line-height: 1.1em; white-space: nowrap; text-overflow: ellipsis } .small-header-icons { padding-left: 7px; padding-right: 7px; margin-top: 14px; width: 60px } .small-header-icons:hover { text-decoration: none } @media only screen and (max-width: 75em) { .breadcrumbs { padding: 10px 20px 10px 0 } } .sticky-header { width: 100%; height: 39px; position: fixed; top: 0 } .sticky-header .menu-button { top: 0; margin: 7px 0 } .header-logo-container { padding: 15px 20px } .sticky-header .header-logo-container { padding: 7px 0 7px 20px; height: 25px } .sticky-header .header-logo { height: 25px } .sticky-header .header-logo img { max-height: 25px } .sticky-header .small-header-icons { border-left: 1px solid #8d8d78; padding: 7px 16px; background-color: #5a5a62; margin-top: 0; margin-right: 0; width: auto } .sticky-header .small-header-icons:first-of-type { border-left: 0 } .sticky-header .small-header-main { width: auto; margin: 0 } .nature-research-logo { width: 299px; background-position: 50% 50%; background-repeat: no-repeat } .small-header-side { right: 0 } .sticky-header .small-header-side { width: auto; float: right; margin: 0; position: static } .sticky-header .small-header-hide { display: none; visibility: hidden } .sticky-header .small-header-show { display: inline; visibility: visible } .banner .header-tools-show { display: block; visibility: visible } .header-logo-container, .header-logo { height: 50px; overflow: hidden } .header-logo img { max-height: 50px; margin: 0; padding: 0 } .header-logo-primary, .sticky-header .header-logo-secondary { display: inline; visibility: visible } .header-logo-secondary, .sticky-header .header-logo-primary { display: none; visibility: hidden } .menu-button, .menu-button-clone { position: absolute; top: 15px; right: 100%; padding: 6px 10px; border: 1px solid #222; border: 1px solid rgba(34, 34, 34, .75); text-transform: uppercase; font-size: 1.4rem; color: #222 } .menu-button:hover, .menu-button:focus, .menu-button-clone:hover, .menu-button-clone:focus { text-decoration: none } .menu-button-icon { display: block; position: relative; padding-right: 15px; line-height: 1em; text-align: right; background-repeat: no-repeat; background-position: 100% 50% } .menu-button-icon:after { width: 12px; height: 7px; background-image: url(data:image/svg+xml;base64,PHN2ZyB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciIHdpZHRoPSIxMiIgaGVpZ2h0PSI3IiB2aWV3Qm94PSIwIDAgMTIgNyI+PHBhdGggZmlsbD0iIzIyMiIgZD0iTTkuNyAwTDYgNC4zIDIuMyAwSDBsNiA3IDYtN0g5Ljd6Ii8+PC9zdmc+), none; background-size: 12px auto } .menu-button-label { padding-right: 4px } .menu-button-icon, .menu-button-label { height: 11px; line-height: 11px } .menu-button-icon { min-width: 45px } @media only screen and (max-width: 75em) { .small-header-side { right: 20px } .sticky-header .menu-button, .menu-button { display: inline-block; float: none; vertical-align: top; position: static; margin: 1px 20px 1px 0 } .up-next { display: none } .menu-button-icon { min-width: 0 } .menu-button-label { display: none } .menu-button-icon { padding-right: 12px } .sticky-header .header-logo-container, .header-logo-container { padding-left: 0 } .banner { padding-left: 20px; padding-right: 0 } } @media only screen and (max-width: 54.688em) { .menu-button { margin: 1px 20px 1px 0 } .header-logo-container { padding: 7px 20px 7px 0; height: 25px } .header-logo { height: 25px } .header-logo img { max-height: 25px } .header-logo-primary { display: none; visibility: hidden } .header-logo-secondary { display: inline; visibility: visible } .small-header-icons { border-left: 1px solid #8d8d78; margin-top: 0; margin-right: 0; padding: 7px 16px; width: auto; background-color: #5a5a62 } .small-header-icons:first-of-type { border-left: 0 } .small-header-main { width: auto; margin: 0 } .small-header-side { width: auto; float: right; margin: 0; position: static } .nature-research-logo { width: 231px; margin-right: -20px } .menu .menu-row { padding: 0 } .menu .menu-cell ul { margin: 0 } .menu .menu-cell li { display: block; padding: 20px; float: none; border-bottom: 1px solid #dadada } .menu .background-gradient-brand-gray { background-image: none } .menu h2 { margin: 0; padding: 20px } } @media only screen and (max-width: 40em) { .menu-button, .sticky-header .menu-button { margin-right: 4px } .sticky-header .header-logo-primary, .header-logo-primary { display: inline; visibility: visible } .header-logo-secondary, .sticky-header .header-logo-secondary { display: none; visibility: hidden } } .js .menu { position: absolute; overflow-y: auto; left: 0; right: 0; top: -500px; opacity: 0; margin: 0 } .js .sticky-header ~ .menu { position: fixed } .js .menu-open { opacity: 1 } .beta-switch { display: block; background-color: #069; color: #fff } .beta-switch a, .beta-switch a:visited { color: #fff; text-decoration: underline; -webkit-text-decoration-skip: skip; text-decoration-skip-ink: auto } @media only screen and (max-width: 75em) and (min-width: 54.74em) { .banner { padding-right: 20px } } .cookie-banner { background-color: #303030 } .cookie-banner .icon { background-image: url(data:image/svg+xml;base64,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), none; background-size: 16px 16px; padding-left: 21px } .accept-btn { background-color: #303030; border: none; cursor: pointer; text-decoration: none } .accept-btn:hover { text-decoration: underline; -webkit-text-decoration-skip: skip; text-decoration-skip-ink: auto; cursor: pointer } .animate-opacity-top { -webkit-transition: opacity .5s ease-out, top .5s ease-out; -moz-transition: opacity .5s ease-out, top .5s ease-out; transition: opacity .5s ease-out, top .5s ease-out } .notransition { -webkit-transition: none !important; -moz-transition: none !important; -o-transition: none !important; -ms-transition: none !important; transition: none !important } .wysiwyg .box { border: 1px solid #e7e7e7; background-color: #fff } .wysiwyg h1, .wysiwyg h2, .wysiwyg h3, .wysiwyg h4, .wysiwyg h5, .wysiwyg h6 { color: #222; font-family: Lora, Palatino, Times, Times New Roman, serif } .wysiwyg .content-image { margin: 6px 20px; max-width: 50%; display: block } .wysiwyg .content-image-left { float: left; margin-left: 0 } .wysiwyg .content-image-right { float: right; margin-right: 0 } @media only screen and (max-width: 40em) { .wysiwyg .content-image { margin: 0 0 28px; max-width: 100%; float: none } } .js-image { width: 33% } .content-image-left { margin: 7px 28px 14px 0; float: left } .content-image-right { margin: 7px 0 14px 28px; float: right } .content-image-center { margin: 0 auto 28px } .content-image-half { margin: 7px 28px 14px 0; float: left; width: auto; max-width: 50% } .max-width-content-image { max-width: 50% } .max-width-third { max-width: 33% } .credit { font-size: 1rem; margin: 6px 10px; color: #fff; position: absolute; display: inline-block; text-shadow: 0 0 1px #222, 0 1px 1px #222, 1px 0 1px #222, 1px 1px 1px #222, -1px 0 1px #222, 0 -1px 1px #222, -1px -1px 1px #222 } .ie9 .credit { background: #222; padding: 2px 4px; margin: 6px } @media only screen and (max-width: 54.688em) and (min-width: 40.06em) { .just-mq875-content-image-center { margin: 0 auto 28px; float: none; max-width: 100% } } @media only screen and (max-width: 30em) { .just-mq480-content-image-center { margin: 0 auto 28px; 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