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Лајнвивер—Берков дијаграм — Википедија

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class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Садржај" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Прикажи/сакриј садржај" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Прикажи/сакриј садржај</span> </label> <div class="vector-dropdown-content"> <div 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Доступан на: 22" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-22" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">22 језика</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Lineweaver%E2%80%93Burkov_dijagram" title="Lineweaver–Burkov dijagram — босански" lang="bs" hreflang="bs" data-title="Lineweaver–Burkov dijagram" data-language-autonym="Bosanski" data-language-local-name="босански" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Representaci%C3%B3_de_Lineweaver-Burk" title="Representació de Lineweaver-Burk — каталонски" lang="ca" hreflang="ca" data-title="Representació de Lineweaver-Burk" data-language-autonym="Català" data-language-local-name="каталонски" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Lineweaver-Burk-plot" title="Lineweaver-Burk-plot — дански" lang="da" hreflang="da" data-title="Lineweaver-Burk-plot" data-language-autonym="Dansk" data-language-local-name="дански" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Lineweaver%E2%80%93Burk_plot" title="Lineweaver–Burk plot — енглески" lang="en" hreflang="en" data-title="Lineweaver–Burk plot" data-language-autonym="English" data-language-local-name="енглески" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Diagrama_de_Lineweaver-Burk" title="Diagrama de Lineweaver-Burk — шпански" lang="es" hreflang="es" data-title="Diagrama de Lineweaver-Burk" data-language-autonym="Español" data-language-local-name="шпански" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%B7%D8%B1%D8%AD_%D9%84%D8%A7%DB%8C%D9%86%D9%88%DB%8C%D9%88%D8%B1_%D8%A8%D8%B1%DA%A9" title="طرح لاینویور برک — персијски" lang="fa" hreflang="fa" data-title="طرح لاینویور برک" data-language-autonym="فارسی" data-language-local-name="персијски" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Diagramme_de_Lineweaver%E2%80%93Burk" title="Diagramme de Lineweaver–Burk — француски" lang="fr" hreflang="fr" data-title="Diagramme de Lineweaver–Burk" data-language-autonym="Français" data-language-local-name="француски" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Gr%C3%A1fica_de_Lineweaver-Burk" title="Gráfica de Lineweaver-Burk — галицијски" lang="gl" hreflang="gl" data-title="Gráfica de Lineweaver-Burk" data-language-autonym="Galego" data-language-local-name="галицијски" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%92%D7%A8%D7%A3_%D7%9C%D7%99%D7%99%D7%A0%D7%95%D7%95%D7%99%D7%91%D7%A8-%D7%91%D7%95%D7%A8%D7%A7" title="גרף ליינוויבר-בורק — хебрејски" lang="he" hreflang="he" data-title="גרף ליינוויבר-בורק" data-language-autonym="עברית" data-language-local-name="хебрејски" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Lineweaver-Burkov_dijagram" title="Lineweaver-Burkov dijagram — хрватски" lang="hr" hreflang="hr" data-title="Lineweaver-Burkov dijagram" data-language-autonym="Hrvatski" data-language-local-name="хрватски" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%BC%D5%A1%D5%B5%D5%B6%D5%B8%D5%BE%D5%A5%D6%80-%D4%B2%D5%A5%D6%80%D5%A3%D5%AB_%D5%A4%D5%AB%D5%A1%D5%A3%D6%80%D5%A1%D5%B4" title="Լայնովեր-Բերգի դիագրամ — јерменски" lang="hy" hreflang="hy" data-title="Լայնովեր-Բերգի դիագրամ" data-language-autonym="Հայերեն" data-language-local-name="јерменски" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Diagramma_di_Lineweaver-Burk" title="Diagramma di Lineweaver-Burk — италијански" lang="it" hreflang="it" data-title="Diagramma di Lineweaver-Burk" data-language-autonym="Italiano" data-language-local-name="италијански" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%A9%E3%82%A4%E3%83%B3%E3%82%A6%E3%82%A3%E3%83%BC%E3%83%90%E3%83%BC%EF%BC%9D%E3%83%90%E3%83%BC%E3%82%AF%E3%83%97%E3%83%AD%E3%83%83%E3%83%88" title="ラインウィーバー=バークプロット — јапански" lang="ja" hreflang="ja" data-title="ラインウィーバー=バークプロット" data-language-autonym="日本語" data-language-local-name="јапански" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EB%9D%BC%EC%9D%B8%EC%9C%84%EB%B2%84-%EB%B2%84%ED%81%AC_%EB%B0%A9%EC%A0%95%EC%8B%9D" title="라인위버-버크 방정식 — корејски" lang="ko" hreflang="ko" data-title="라인위버-버크 방정식" data-language-autonym="한국어" data-language-local-name="корејски" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Lineweaver%E2%80%93Burk-plott" title="Lineweaver–Burk-plott — норвешки букмол" lang="nb" hreflang="nb" data-title="Lineweaver–Burk-plott" data-language-autonym="Norsk bokmål" data-language-local-name="норвешки букмол" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Diagrama_de_Lineweaver-Burke" title="Diagrama de Lineweaver-Burke — португалски" lang="pt" hreflang="pt" data-title="Diagrama de Lineweaver-Burke" data-language-autonym="Português" data-language-local-name="португалски" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%93%D1%80%D0%B0%D1%84%D0%B8%D0%BA_%D0%9B%D0%B0%D0%B9%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80%D0%B0_%E2%80%94_%D0%91%D0%B5%D1%80%D0%BA%D0%B0" title="График Лайнвивера — Берка — руски" lang="ru" hreflang="ru" data-title="График Лайнвивера — Берка" data-language-autonym="Русский" data-language-local-name="руски" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Lineweaver-Burkova_ena%C4%8Dba" title="Lineweaver-Burkova enačba — словеначки" lang="sl" hreflang="sl" data-title="Lineweaver-Burkova enačba" data-language-autonym="Slovenščina" data-language-local-name="словеначки" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Lineweaver-Burkov_dijagram" title="Lineweaver-Burkov dijagram — српскохрватски" lang="sh" hreflang="sh" data-title="Lineweaver-Burkov dijagram" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="српскохрватски" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Lineweaver%E2%80%93Burk-yht%C3%A4l%C3%B6" title="Lineweaver–Burk-yhtälö — фински" lang="fi" hreflang="fi" data-title="Lineweaver–Burk-yhtälö" data-language-autonym="Suomi" data-language-local-name="фински" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%93%D1%80%D0%B0%D1%84%D1%96%D0%BA_%D0%9B%D0%B0%D0%B9%D0%BD%D0%B2%D1%96%D0%B2%D0%B5%D1%80%D0%B0_%E2%80%94_%D0%91%D0%B5%D1%80%D0%BA%D0%B0" title="Графік Лайнвівера — Берка — украјински" lang="uk" hreflang="uk" data-title="Графік Лайнвівера — Берка" data-language-autonym="Українська" data-language-local-name="украјински" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%8F%8C%E5%80%92%E6%95%B0%E5%9B%BE" title="双倒数图 — кинески" lang="zh" hreflang="zh" data-title="双倒数图" data-language-autonym="中文" data-language-local-name="кинески" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q3434574#sitelinks-wikipedia" title="Уреди међујезичке везе" class="wbc-editpage">Уреди везе</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Именски простори"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div 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href="/w/index.php?title=%D0%9B%D0%B0%D1%98%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80%E2%80%94%D0%91%D0%B5%D1%80%D0%BA%D0%BE%D0%B2_%D0%B4%D0%B8%D1%98%D0%B0%D0%B3%D1%80%D0%B0%D0%BC&amp;action=edit" title="Уредите изворни код ове странице [e]" accesskey="e"><span>Уреди извор</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=%D0%9B%D0%B0%D1%98%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80%E2%80%94%D0%91%D0%B5%D1%80%D0%BA%D0%BE%D0%B2_%D0%B4%D0%B8%D1%98%D0%B0%D0%B3%D1%80%D0%B0%D0%BC&amp;action=history"><span>Историја</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Опште </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a 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class="mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:QrCode&amp;url=https%3A%2F%2Fsr.wikipedia.org%2Fwiki%2F%25D0%259B%25D0%25B0%25D1%2598%25D0%25BD%25D0%25B2%25D0%25B8%25D0%25B2%25D0%25B5%25D1%2580%25E2%2580%2594%25D0%2591%25D0%25B5%25D1%2580%25D0%25BA%25D0%25BE%25D0%25B2_%25D0%25B4%25D0%25B8%25D1%2598%25D0%25B0%25D0%25B3%25D1%2580%25D0%25B0%25D0%25BC"><span>Преузми QR код</span></a></li> </ul> </div> </div> <div id="p-electronpdfservice-sidebar-portlet-heading" class="vector-menu mw-portlet mw-portlet-electronpdfservice-sidebar-portlet-heading" > <div class="vector-menu-heading"> Штампање/извоз </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="electron-print_pdf" class="mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:DownloadAsPdf&amp;page=%D0%9B%D0%B0%D1%98%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80%E2%80%94%D0%91%D0%B5%D1%80%D0%BA%D0%BE%D0%B2_%D0%B4%D0%B8%D1%98%D0%B0%D0%B3%D1%80%D0%B0%D0%BC&amp;action=show-download-screen"><span>Преузми у PDF-у</span></a></li><li id="t-print" class="mw-list-item"><a href="javascript:print();" rel="alternate" title="Одштампајте ову страницу [p]" accesskey="p"><span>Одштампај</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> На другим пројектима </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Lineweaver%E2%80%93Burk_plots" hreflang="en"><span>Викиостава</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q3434574" title="Веза ка ставци на спремишту података [g]" accesskey="g"><span>Ставка на Википодацима</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Алатке странице"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Изглед"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Изглед</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">сакриј</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">С Википедије, слободне енциклопедије</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sr" dir="ltr"><figure class="mw-default-size mw-halign-right" typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:Lineweaver-Burke_plot.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Lineweaver-Burke_plot.svg/420px-Lineweaver-Burke_plot.svg.png" decoding="async" width="420" height="277" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Lineweaver-Burke_plot.svg/630px-Lineweaver-Burke_plot.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/Lineweaver-Burke_plot.svg/840px-Lineweaver-Burke_plot.svg.png 2x" data-file-width="420" data-file-height="277" /></a><figcaption></figcaption></figure> <p>У <a href="/wiki/%D0%91%D0%B8%D0%BE%D1%85%D0%B5%D0%BC%D0%B8%D1%98%D0%B0" title="Биохемија">биохемији</a>, <b>Лајнвивер—Берков дијаграм</b> (или дупли рецирпочни дијаграм) графички је приказ Лајнвивер—Беркове једначине за <a href="/wiki/%D0%A5%D0%B5%D0%BC%D0%B8%D1%98%D1%81%D0%BA%D0%B0_%D0%BA%D0%B8%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0" title="Хемијска кинетика">кинетику</a> <a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC" title="Ензим">ензима</a>, коју су извели амерички научници <a href="/w/index.php?title=%D0%A5%D0%B0%D0%BD%D1%81_%D0%9B%D0%B0%D1%98%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80&amp;action=edit&amp;redlink=1" class="new" title="Ханс Лајнвивер (страница не постоји)">Ханс Лајнвивер</a> и <a href="/w/index.php?title=%D0%94%D0%B8%D0%BD_%D0%91%D0%B5%D1%80%D0%BA&amp;action=edit&amp;redlink=1" class="new" title="Дин Берк (страница не постоји)">Дин Берк</a>. Овај дијаграм обезбеђује користан графички метод за анализу <a href="/wiki/%D0%9C%D0%B8%D1%85%D0%B0%D0%B5%D0%BB%D0%B8%D1%81%E2%80%94%D0%9C%D0%B5%D0%BD%D1%82%D0%B5%D0%BD%D0%B8%D0%BD%D0%B0_%D0%BA%D0%B8%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0" title="Михаелис—Ментенина кинетика">Михаелис—Ментенине</a> једначине: </p> <dl><dd><span class="mwe-math-element"><span class="mwe-math-mathml-inline mwe-math-mathml-a11y" style="display: none;"><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle V=V_{max}{\frac {[S]}{K_{m}+[S]}}}"> <semantics> <mrow class="MJX-TeXAtom-ORD"> <mstyle displaystyle="true" scriptlevel="0"> <mi>V</mi> <mo>=</mo> <msub> <mi>V</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>m</mi> <mi>a</mi> <mi>x</mi> </mrow> </msub> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mrow> <mo stretchy="false">[</mo> <mi>S</mi> <mo stretchy="false">]</mo> </mrow> <mrow> <msub> <mi>K</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>m</mi> </mrow> </msub> <mo>+</mo> <mo stretchy="false">[</mo> <mi>S</mi> <mo stretchy="false">]</mo> </mrow> </mfrac> </mrow> </mstyle> </mrow> <annotation encoding="application/x-tex">{\displaystyle V=V_{max}{\frac {[S]}{K_{m}+[S]}}}</annotation> </semantics> </math></span><img src="https://wikimedia.org/api/rest_v1/media/math/render/svg/16e858174569d133bc08e9c5ada05212d88a418f" class="mwe-math-fallback-image-inline mw-invert skin-invert" aria-hidden="true" style="vertical-align: -2.671ex; width:19.843ex; height:6.509ex;" alt="{\displaystyle V=V_{max}{\frac {[S]}{K_{m}+[S]}}}"></span></dd></dl> <p>Реципрочна једначина је: </p> <dl><dd><span class="mwe-math-element"><span class="mwe-math-mathml-inline mwe-math-mathml-a11y" style="display: none;"><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle {1 \over V}={(K_{m}+[S]) \over (V_{max}[S])}={K_{m} \over V_{max}}{1 \over [S]}+{1 \over V_{max}}}"> <semantics> <mrow class="MJX-TeXAtom-ORD"> <mstyle displaystyle="true" scriptlevel="0"> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mn>1</mn> <mi>V</mi> </mfrac> </mrow> <mo>=</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mrow> <mo stretchy="false">(</mo> <msub> <mi>K</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>m</mi> </mrow> </msub> <mo>+</mo> <mo stretchy="false">[</mo> <mi>S</mi> <mo stretchy="false">]</mo> <mo stretchy="false">)</mo> </mrow> <mrow> <mo stretchy="false">(</mo> <msub> <mi>V</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>m</mi> <mi>a</mi> <mi>x</mi> </mrow> </msub> <mo stretchy="false">[</mo> <mi>S</mi> <mo stretchy="false">]</mo> <mo stretchy="false">)</mo> </mrow> </mfrac> </mrow> <mo>=</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <msub> <mi>K</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>m</mi> </mrow> </msub> <msub> <mi>V</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>m</mi> <mi>a</mi> <mi>x</mi> </mrow> </msub> </mfrac> </mrow> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mn>1</mn> <mrow> <mo stretchy="false">[</mo> <mi>S</mi> <mo stretchy="false">]</mo> </mrow> </mfrac> </mrow> <mo>+</mo> <mrow class="MJX-TeXAtom-ORD"> <mfrac> <mn>1</mn> <msub> <mi>V</mi> <mrow class="MJX-TeXAtom-ORD"> <mi>m</mi> <mi>a</mi> <mi>x</mi> </mrow> </msub> </mfrac> </mrow> </mstyle> </mrow> <annotation encoding="application/x-tex">{\displaystyle {1 \over V}={(K_{m}+[S]) \over (V_{max}[S])}={K_{m} \over V_{max}}{1 \over [S]}+{1 \over V_{max}}}</annotation> </semantics> </math></span><img src="https://wikimedia.org/api/rest_v1/media/math/render/svg/696639019ef0572ec2042e7e259b3fa61900767d" class="mwe-math-fallback-image-inline mw-invert skin-invert" aria-hidden="true" style="vertical-align: -2.671ex; width:38.569ex; height:6.509ex;" alt="{\displaystyle {1 \over V}={(K_{m}+[S]) \over (V_{max}[S])}={K_{m} \over V_{max}}{1 \over [S]}+{1 \over V_{max}}}"></span></dd></dl> <p>где је <i>V</i> брзина реакције, <i>K</i><sub>m</sub> је <a href="/wiki/%D0%9C%D0%B8%D1%85%D0%B0%D0%B5%D0%BB%D0%B8%D1%81%E2%80%94%D0%9C%D0%B5%D0%BD%D1%82%D0%B5%D0%BD%D0%B8%D0%BD%D0%B0_%D0%BA%D0%B8%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0" title="Михаелис—Ментенина кинетика">Михаелис—Ментенина константа</a>, <i>V</i><sub>max</sub> је максимална брзина реакције, док је [<i>S</i>] <a href="/wiki/%D0%9A%D0%BE%D0%BD%D1%86%D0%B5%D0%BD%D1%82%D1%80%D0%B0%D1%86%D0%B8%D1%98%D0%B0" title="Концентрација">концентрација</a> супстрата. </p><p>Лајнвивер—Берков дијаграм је користан за брзо одређивање неопходних параметара у кинетици ензима, као што су <i>K</i><sub>m</sub> и V<sub>max</sub>. Примера ради, одесчак на <a href="/w/index.php?title=Y-%D0%BE%D1%81%D0%B0&amp;action=edit&amp;redlink=1" class="new" title="Y-оса (страница не постоји)">y-оси</a> је једнак <a href="/wiki/%D0%A0%D0%B5%D1%86%D0%B8%D0%BF%D1%80%D0%BE%D1%87%D0%BD%D0%B0_%D0%B2%D1%80%D0%B5%D0%B4%D0%BD%D0%BE%D1%81%D1%82" title="Реципрочна вредност">реципрочној вредности</a> <i>V</i><sub>max</sub>; док се одсечак на <a href="/wiki/%D0%9E%D1%81%D0%B0" class="mw-disambig" title="Оса">x-оси</a> изједначава са −1/K<sub>m</sub>. </p><p>С обзиром да је Лајнвивер—Берков дијаграм јако осетљив на експерименталне грешке, самим тим је и поприлично непоуздан. Тако да се у данашње време више користи или <a href="/wiki/Nelinearna_regresija" title="Nelinearna regresija">нелинеарна регресија</a> или алтернативна форма Михаелис—Ментенине једначине, као што је <a href="/wiki/%D0%95%D0%B4%D0%B8%E2%80%94%D0%A5%D0%BE%D1%84%D1%81%D1%82%D0%B8%D1%98%D0%B5%D0%B2_%D0%B4%D0%B8%D1%98%D0%B0%D0%B3%D1%80%D0%B0%D0%BC" title="Еди—Хофстијев дијаграм">Еди—Хофстијев дијаграм</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Спољашње_везе"><span id=".D0.A1.D0.BF.D0.BE.D1.99.D0.B0.D1.88.D1.9A.D0.B5_.D0.B2.D0.B5.D0.B7.D0.B5"></span>Спољашње везе</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%9B%D0%B0%D1%98%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80%E2%80%94%D0%91%D0%B5%D1%80%D0%BA%D0%BE%D0%B2_%D0%B4%D0%B8%D1%98%D0%B0%D0%B3%D1%80%D0%B0%D0%BC&amp;veaction=edit&amp;section=1" title="Уредите одељак „Спољашње везе”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%9B%D0%B0%D1%98%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80%E2%80%94%D0%91%D0%B5%D1%80%D0%BA%D0%BE%D0%B2_%D0%B4%D0%B8%D1%98%D0%B0%D0%B3%D1%80%D0%B0%D0%BC&amp;action=edit&amp;section=1" title="Уреди извор одељка: Спољашње везе"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20060505072624/http://www.graphpad.com/curvefit/lineweaver__burk_.htm">Кинетика ензима и Лајнвивер—Берков дијаграм</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r25469611">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline 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href="/wiki/Aktivno_mesto" title="Aktivno mesto">Активно место</a></li> <li><a href="/wiki/Alosterna_regulacija" title="Alosterna regulacija">Алостерна регулација</a></li> <li><a href="/wiki/Mesto_vezivanja" title="Mesto vezivanja">Место везивања</a></li> <li><a href="/wiki/Kataliti%C4%8Dki_perfektan_enzim" title="Katalitički perfektan enzim">Каталитички перфектан ензим</a></li> <li><a href="/wiki/Kofaktor_(biohemija)" title="Kofaktor (biohemija)">Коензим</a></li> <li><a href="/wiki/Kofaktor_(biohemija)" title="Kofaktor (biohemija)">Кофактор</a></li> <li><a href="/wiki/Kooperativnost_(biohemija)" title="Kooperativnost (biohemija)">Кооперативност</a></li> <li><a href="/wiki/Klasifikacija_enzima" title="Klasifikacija enzima">ЕЦ број</a></li> <li><a href="/wiki/Enzimska_kataliza" title="Enzimska kataliza">Ензимска катализа</a></li> <li><a href="/wiki/%D0%98%D0%BD%D0%B4%D1%83%D0%BA%D1%86%D0%B8%D1%98%D0%B0_%D0%B8_%D0%B8%D0%BD%D1%85%D0%B8%D0%B1%D0%B8%D1%86%D0%B8%D1%98%D0%B0_%D0%B5%D0%BD%D0%B7%D0%B8%D0%BC%D1%81%D0%BA%D0%B8%D1%85_%D1%80%D0%B5%D0%B0%D0%BA%D1%86%D0%B8%D1%98%D0%B0" title="Индукција и инхибиција ензимских реакција">Индукција и инхибиција ензима</a></li> <li><a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC%D1%81%D0%BA%D0%B0_%D0%BA%D0%B8%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0" title="Ензимска кинетика">Ензимска кинетика</a></li> <li><a class="mw-selflink selflink">Лајнвивер—Берков дијаграм</a></li> <li><a href="/wiki/%D0%9C%D0%B8%D1%85%D0%B0%D0%B5%D0%BB%D0%B8%D1%81%E2%80%94%D0%9C%D0%B5%D0%BD%D1%82%D0%B5%D0%BD%D0%B8%D0%BD%D0%B0_%D0%BA%D0%B8%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0" title="Михаелис—Ментенина кинетика">Михаелис—Ментенина кинетика</a></li> <li><a href="/wiki/Spisak_enzima" title="Spisak enzima">Списак ензима</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Типови</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>ЕЦ1 <a href="/wiki/Oksidoreduktaza" title="Oksidoreduktaza">Оксидоредуктазе</a></b>/<a href="/wiki/Spisak_EC_brojeva_(EC_1)" title="Spisak EC brojeva (EC 1)">списак</a></li> <li><b>ЕЦ2 <a href="/wiki/Transferaza" title="Transferaza">Трансферазе</a></b>/<a href="/wiki/Spisak_EC_brojeva_(EC_2)" title="Spisak EC brojeva (EC 2)">списак</a></li> <li><b>ЕЦ3 <a href="/wiki/Hidrolaza" title="Hidrolaza">Хидролазе</a></b>/<a href="/wiki/Spisak_EC_brojeva_(EC_3)" title="Spisak EC brojeva (EC 3)">списак</a></li> <li><b>ЕЦ4 <a href="/wiki/Lijaza" title="Lijaza">Лијазе</a></b>/<a href="/wiki/Spisak_EC_brojeva_(EC_4)" title="Spisak EC brojeva (EC 4)">списак</a></li> <li><b>ЕЦ5 <a href="/wiki/Izomeraza" title="Izomeraza">Изомеразе</a></b>/<a href="/wiki/Spisak_EC_brojeva_(EC_5)" title="Spisak EC brojeva (EC 5)">списак</a></li> <li><b>ЕЦ6 <a href="/wiki/Ligaza" title="Ligaza">Лигазе</a></b>/<a href="/wiki/Spisak_EC_brojeva_(EC_6)" title="Spisak EC brojeva (EC 6)">списак</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div> <ul><li><i><a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Biohemija_metanavs-lat" title="Шаблон:Biohemija metanavs-lat">Б</a> <a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC" title="Ензим">ензм</a>: <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Alkoholne_oksidoreduktaze-lat" title="Шаблон:Alkoholne oksidoreduktaze-lat">1.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Aldehid/Okso_oksidoreduktaze-lat" title="Шаблон:Aldehid/Okso oksidoreduktaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:CH-CH_oksidoreduktaze-lat" title="Шаблон:CH-CH oksidoreduktaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:CH-NH2_oksidoreduktaze-lat" title="Шаблон:CH-NH2 oksidoreduktaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:CH-NH_oksidoreduktaze-lat" title="Шаблон:CH-NH oksidoreduktaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:NADH_ili_NADPH_oksidoreduktaze-lat" title="Шаблон:NADH ili NADPH oksidoreduktaze-lat">6</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Azotni_donor_oksidoreduktaze-lat" title="Шаблон:Azotni donor oksidoreduktaze-lat">7</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Sumporne_oksidoreduktaze-lat" title="Шаблон:Sumporne oksidoreduktaze-lat">8</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Difenolna_familija_oksidoreduktaza-lat" title="Шаблон:Difenolna familija oksidoreduktaza-lat">10</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Peroksidaze-lat" title="Шаблон:Peroksidaze-lat">11</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Monooksigenaze-lat" title="Шаблон:Monooksigenaze-lat">13</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Dioksigenaze-lat" title="Шаблон:Dioksigenaze-lat">14</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Druge_oksidoreduktaze-lat" title="Шаблон:Druge oksidoreduktaze-lat">15-18</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Jedan_ugljenik_transferaze-lat" class="mw-redirect" title="Шаблон:Jedan ugljenik transferaze-lat">2.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Aldehid-keton_transferaze-lat" title="Шаблон:Aldehid-keton transferaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Aciltransferaze-lat" title="Шаблон:Aciltransferaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Glikoziltransferaze-lat" title="Шаблон:Glikoziltransferaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Alkil_i_aril_transferaze-lat" title="Шаблон:Alkil i aril transferaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Azotne_transferaze-lat" title="Шаблон:Azotne transferaze-lat">6</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Kinaze-lat" title="Шаблон:Kinaze-lat">7</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Sumpor-sadr%C5%BEavaju%C4%87e-grupe_transferaze-lat" class="mw-redirect" title="Шаблон:Sumpor-sadržavajuće-grupe transferaze-lat">8</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Tirozinske_kinaze-lat" title="Шаблон:Tirozinske kinaze-lat">2.7.10</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Serin/treonin_specifi%C4%8Dne_proteinske_kinaze-lat" class="mw-redirect" title="Шаблон:Serin/treonin specifične proteinske kinaze-lat">2.7.11-12</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Esteraze-lat" title="Шаблон:Esteraze-lat">3.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:%C5%A0e%C4%87erne_hidrolaze-lat" title="Шаблон:Šećerne hidrolaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Etarska_veza_hidrolaze-lat" title="Шаблон:Etarska veza hidrolaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Proteaze-lat" title="Шаблон:Proteaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-azot_ne-peptidne_hidrolaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-azot ne-peptidne hidrolaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Hidrolaze_kiselinskih_anhidrida-lat" title="Шаблон:Hidrolaze kiselinskih anhidrida-lat">6</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-ugljenik_hidrolaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-ugljenik hidrolaze-lat">7</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Proteinske_tirozinske_fosfataze-lat" title="Шаблон:Proteinske tirozinske fosfataze-lat">3.1.3.48</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Serinske_endopeptidaze-lat" title="Шаблон:Serinske endopeptidaze-lat">3.4.21</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Cisteinske_proteaze-lat" title="Шаблон:Cisteinske proteaze-lat">22</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Proteaze_asparaginske_kiseline-lat" class="mw-redirect" title="Шаблон:Proteaze asparaginske kiseline-lat">23</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Metaloendopeptidaze-lat" title="Шаблон:Metaloendopeptidaze-lat">24</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-ugljenik_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-ugljenik liaze-lat">4.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-kiseonik_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-kiseonik liaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-azot_liaze-lat" title="Шаблон:Ugljenik-azot liaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-sumpor_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-sumpor liaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-halid_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-halid liaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Fosfor-kiseonik_liaze-lat" title="Шаблон:Fosfor-kiseonik liaze-lat">6</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Racemaze_i_epimeraze-lat" title="Шаблон:Racemaze i epimeraze-lat">5.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Geometrijske_izomeraze-lat" title="Шаблон:Geometrijske izomeraze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Intramolekularne_oksidoreduktaze-lat" title="Шаблон:Intramolekularne oksidoreduktaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Mutaze-lat" title="Шаблон:Mutaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Topoizomeraze-lat" title="Шаблон:Topoizomeraze-lat">99</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ligaze_CO_CS_i_CN-lat" title="Шаблон:Ligaze CO CS i CN-lat">6.1-3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-ugljenik_ligaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-ugljenik ligaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Fosforni_estar_i_azot-metal_ligaze-lat" title="Шаблон:Fosforni estar i azot-metal ligaze-lat">5-6</a></i></li></ul> </div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐api‐int.codfw.main‐648bd44df8‐k4x47 Cached time: 20241116222347 Cache expiry: 2592000 Reduced expiry: false Complications: [] CPU time usage: 0.183 seconds Real time usage: 0.333 seconds Preprocessor visited node count: 93/1000000 Post‐expand include size: 18798/2097152 bytes Template argument size: 0/2097152 bytes Highest expansion depth: 5/100 Expensive parser function count: 0/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 7857/5000000 bytes Lua time usage: 0.113/10.000 seconds Lua memory usage: 1272515/52428800 bytes Number of Wikibase entities loaded: 1/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 100.00% 159.531 1 -total 73.42% 117.135 1 Шаблон:Ензими 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