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Lasinavir - Wikipedia
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Available in 2 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-2" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">2 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Lasinavir" title="Lasinavir – Vietnamese" lang="vi" hreflang="vi" data-title="Lasinavir" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E6%8B%89%E8%A5%BF%E9%82%A3%E9%9F%A6" title="拉西那韦 – Chinese" lang="zh" hreflang="zh" data-title="拉西那韦" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q24975733#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Lasinavir" title="View the content 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data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">hide</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r1084375498">.mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}</style> <table class="infobox ib-chembox"> <caption>Lasinavir </caption> <tbody><tr> <td colspan="2" style="text-align:center; padding:2px;"><span typeof="mw:File"><a href="/wiki/File:Lasinavir.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3d/Lasinavir.svg/200px-Lasinavir.svg.png" decoding="async" width="200" height="182" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3d/Lasinavir.svg/300px-Lasinavir.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3d/Lasinavir.svg/400px-Lasinavir.svg.png 2x" data-file-width="512" data-file-height="467" /></a></span> </td></tr> <tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Names </th></tr> <tr> <td colspan="2" style="text-align:left;"><a href="/wiki/Chemical_nomenclature#Systematic_name" title="Chemical nomenclature">Systematic IUPAC name</a> <div style="max-width:22em; word-wrap:break-word; padding-left:1.7em;"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0; max-width:22em;"><i>tert</i>-Butyl (3<i>S</i>,4<i>S</i>,6<i>R</i>,9<i>S</i>)-13-benzyl-12-hydroxy-6,9-dioxo-7-(propan-2-yl)-10-[(2,3,4-trimethoxyphenyl)methyl]-2-oxa-5,8,14-triazapentadecan-15-oate</div></div> </td></tr> <tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Identifiers </th></tr> <tr> <td><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Number</a></div> </td> <td><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li><span title="commonchemistry.cas.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=175385-62-3">175385-62-3</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div> </td></tr> <tr> <td><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;">3D model (<a href="/wiki/JSmol" class="mw-redirect" title="JSmol">JSmol</a>)</div> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="chemapps.stolaf.edu (3D interactive model)"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=CC%28C%29%5BC%40%40H%5D%28C%28%3DO%29NCCOC%29NC%28%3DO%29%5BC%40H%5D%28CC1%3DC%28C%28%3DC%28C%3DC1%29OC%29OC%29OC%29C%5BC%40%40H%5D%28%5BC%40H%5D%28CC2%3DCC%3DCC%3DC2%29NC%28%3DO%29OC%28C%29%28C%29C%29O">Interactive image</a></span></li></ul></div> </td></tr> <tr> <td><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.408297.html">408297</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div> </td></tr> <tr> <td><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/PubChem" title="PubChem">PubChem</a> <abbr title="Compound ID">CID</abbr></div> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/464372">464372</a></span></li></ul></div> </td></tr> <tr> <td><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a> </td> <td><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1126788409"><div class="plainlist"><ul><li><span title="precision.fda.gov"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/0QGV8237I3">0QGV8237I3</a></span><sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup></li></ul></div> </td></tr> <tr> <td colspan="2"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold; text-align:left; font-weight:normal; background:transparent;"><div><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.2em 0 0.2em 1.5em; text-align:left;"><div style="word-wrap:break-word; text-indent:-1.5em; font-size:97%; line-height:120%;">InChI=1S/C35H53N3O9/c1-22(2)29(33(41)36-17-18-43-6)38-32(40)25(20-24-15-16-28(44-7)31(46-9)30(24)45-8)21-27(39)26(19-23-13-11-10-12-14-23)37-34(42)47-35(3,4)5/h10-16,22,25-27,29,39H,17-21H2,1-9H3,(H,36,41)(H,37,42)(H,38,40)/t25-,26+,27+,29+/m1/s1</div><div style="word-wrap:break-word; text-indent:-1.5em; font-size:97%; line-height:120%;">Key: BEUUJDAEPJZWHM-COROXYKFSA-N</div></div></li></ul> </div> </td></tr> <tr> <td colspan="2"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold; text-align:left; font-weight:normal; background:transparent;"><div><a href="/wiki/Simplified_molecular-input_line-entry_system" class="mw-redirect" title="Simplified molecular-input line-entry system">SMILES</a></div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0; word-break:break-all;"><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.2em 0 0.2em 1.6em; word-wrap:break-word; text-indent:-1.5em; text-align:left; font-size:97%; line-height:120%;">CC(C)[C@@H](C(=O)NCCOC)NC(=O)[C@H](CC1=C(C(=C(C=C1)OC)OC)OC)C[C@@H]([C@H](CC2=CC=CC=C2)NC(=O)OC(C)(C)C)O</div></li></ul> </div> </td></tr> <tr> <th colspan="2" style="background: #f8eaba; text-align: center;">Properties </th></tr> <tr> <td><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/Chemical_formula" title="Chemical formula">Chemical formula</a></div> </td> <td>C<sub>35</sub>H<sub>53</sub>N<sub>3</sub>O<sub>9</sub>  </td></tr> <tr> <td><a href="/wiki/Molar_mass" title="Molar mass">Molar mass</a> </td> <td>659.81 g/mol    </td></tr> <tr> <td colspan="2" style="text-align:left; background:#f8eaba; border:1px solid #a2a9b1;"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;">Except where otherwise noted, data are given for materials in their <a href="/wiki/Standard_state" title="Standard state">standard state</a> (at 25 °C [77 °F], 100 kPa).</div> <div style="margin-top: 0.3em;"><div style="text-align:center;"><span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/12px-X_mark.svg.png" decoding="async" width="12" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/18px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/24px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span> (<a href="/wiki/Wikipedia:WikiProject_Chemicals/Chembox_validation" title="Wikipedia:WikiProject Chemicals/Chembox validation">what is</a> <sup><span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span><span typeof="mw:File"><span><img alt="☒" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png" decoding="async" width="7" height="8" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/11px-X_mark.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/14px-X_mark.svg.png 2x" data-file-width="525" data-file-height="600" /></span></span><span style="display:none">N</span></sup> ?) </div></div> <div style="margin-top: 0.3em; text-align: center;"><a href="/wiki/Wikipedia:Chemical_infobox#References" title="Wikipedia:Chemical infobox">Infobox references</a></div> </td></tr> </tbody></table><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Chemical compound</div> <p><b>Lasinavir</b> (<a href="/wiki/International_Nonproprietary_Name" class="mw-redirect" title="International Nonproprietary Name">INN</a>,<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> previously known as <b>BMS-234475</b> and <b>CGP-61755</b>) is an experimental <a href="/wiki/Peptidomimetic" title="Peptidomimetic">peptidomimetic</a> <a href="/wiki/Protease_inhibitor_(pharmacology)" title="Protease inhibitor (pharmacology)">protease inhibitor</a> researched by <a href="/wiki/Novartis" title="Novartis">Novartis</a> and <a href="/wiki/Bristol-Myers_Squibb" class="mw-redirect" title="Bristol-Myers Squibb">Bristol-Myers Squibb</a> as a treatment for <a href="/wiki/HIV/AIDS" title="HIV/AIDS">HIV infection</a>. It was originally discovered by Novartis at <a href="/wiki/Basel" title="Basel">Basel</a> (Switzerland).<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Its investigation was terminated after <a href="/wiki/Phases_of_clinical_research" title="Phases of clinical research">Phase I</a> on October 09, 2002.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lasinavir&action=edit&section=1" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation journal cs1"><a rel="nofollow" class="external text" href="https://www.who.int/medicines/publications/druginformation/innlists/RL38.pdf?ua=1">"International Nonproprietary Names for Pharmaceutical Substances (INN). RECOMMENDED International Nonproprietary Names (Rec. INN): List 38"</a> <span class="cs1-format">(PDF)</span>. <i>WHO Drug Information</i>. <b>11</b> (3). World Health Organization: 170. 1997<span class="reference-accessdate">. Retrieved <span class="nowrap">25 November</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=WHO+Drug+Information&rft.atitle=International+Nonproprietary+Names+for+Pharmaceutical+Substances+%28INN%29.+RECOMMENDED+International+Nonproprietary+Names+%28Rec.+INN%29%3A+List+38&rft.volume=11&rft.issue=3&rft.pages=170&rft.date=1997&rft_id=https%3A%2F%2Fwww.who.int%2Fmedicines%2Fpublications%2Fdruginformation%2Finnlists%2FRL38.pdf%3Fua%3D1&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALasinavir" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"> <style data-mw-deduplicate="TemplateStyles:r1041539562">.mw-parser-output .citation{word-wrap:break-word}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}</style><span class="citation patent" id="harv"><a rel="nofollow" class="external text" href="https://worldwide.espacenet.com/textdoc?DB=EPODOC&IDX=US7348345">B2 US patent 7348345 B2</a>, James Patrick Dunn, Steven Swallow, Zachary Kevin Sweeney, "Nonnucleoside reverse transcriptase inhibitors", issued 2008-08-02</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.number=7348345 B2&rft.cc=US&rft.title=Nonnucleoside+reverse+transcriptase+inhibitors&rft.inventor=James+Patrick+Dunn%2C+Steven+Swallow%2C+Zachary+Kevin+Sweeney&rft.date=2008-08-02"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://adisinsight.springer.com/drugs/800006772">"Drug Profile: Lasinavir"</a>. <i>AdisInsight</i>. Adis International Ltd, part of Springer Science+Business Media<span class="reference-accessdate">. Retrieved <span class="nowrap">25 November</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=AdisInsight&rft.atitle=Drug+Profile%3A+Lasinavir&rft_id=http%3A%2F%2Fadisinsight.springer.com%2Fdrugs%2F800006772&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALasinavir" class="Z3988"></span></span> </li> </ol></div></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol 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style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Lenacapavir" title="Lenacapavir">Lenacapavir (LEN)</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Entry_inhibitor" title="Entry inhibitor">Entry/fusion inhibitors</a> <br /> <i>(<a href="/wiki/Discovery_and_development_of_CCR5_receptor_antagonists" class="mw-redirect" title="Discovery and development of CCR5 receptor antagonists">Discovery and development</a>)</i></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Gp41" title="Gp41">gp41</a></i> (<a href="/wiki/Enfuvirtide" title="Enfuvirtide">Enfuvirtide (ENF, T-20)</a>)<sup>◊</sup></li> <li><i><a href="/wiki/CCR5" title="CCR5">CCR5</a></i> (<a href="/wiki/Maraviroc" title="Maraviroc">Maraviroc (MVC)</a></li> <li><a href="/wiki/Vicriviroc" title="Vicriviroc">Vicriviroc</a><sup>†</sup>, <a href="/wiki/Cenicriviroc" title="Cenicriviroc">Cenicriviroc</a><sup>†</sup>, <a href="/wiki/Leronlimab" title="Leronlimab">Leronlimab</a><sup>†</sup>)</li> <li><i><a href="/wiki/CD4" title="CD4">CD4</a></i> (<a href="/wiki/Ibalizumab" title="Ibalizumab">Ibalizumab (IBA)</a>, <a href="/wiki/Semzuvolimab" title="Semzuvolimab">Semzuvolimab</a><sup>§</sup>)</li> <li><i><a href="/wiki/Gp120" class="mw-redirect" title="Gp120">gp120</a></i> (<a href="/wiki/Fostemsavir" title="Fostemsavir">Fostemsavir (FTR)</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Integrase_inhibitor" title="Integrase inhibitor">Integrase inhibitors</a><br />(Integrase strand transfer inhibitors (INSTI))</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bictegravir" title="Bictegravir">Bictegravir (BIC)</a></li> <li><a href="/wiki/Cabotegravir" title="Cabotegravir">Cabotegravir (CAB)</a></li> <li><a href="/wiki/Dolutegravir" title="Dolutegravir">Dolutegravir (DTG)</a><sup>#</sup></li> <li><a href="/wiki/Elvitegravir" title="Elvitegravir">Elvitegravir (EVG)</a></li> <li><a href="/wiki/Raltegravir" title="Raltegravir">Raltegravir (RAL)</a><sup>#</sup></li> <li><a href="/wiki/BI_224436" title="BI 224436">BI 224436</a><sup>†</sup></li> <li><a href="/wiki/MK-2048" title="MK-2048">MK-2048</a><sup>†</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Maturation_inhibitor" title="Maturation inhibitor">Maturation inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bevirimat" title="Bevirimat">Bevirimat</a><sup>†</sup></li> <li><a href="/wiki/BMS-955176" title="BMS-955176">BMS-955176</a><sup>§</sup></li> <li><a href="/wiki/Fipravirimat" title="Fipravirimat">Fipravirimat</a><sup>§</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Protease_inhibitor_(pharmacology)" title="Protease inhibitor (pharmacology)">Protease Inhibitors (PI)</a><br /><i>(<a href="/wiki/Discovery_and_development_of_HIV_protease_inhibitors" class="mw-redirect" title="Discovery and development of HIV protease inhibitors">Discovery and development</a>)</i></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">1<sup>st</sup> generation</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Amprenavir" title="Amprenavir">Amprenavir (APV)</a><sup>‡</sup></li> <li><a href="/wiki/Fosamprenavir" title="Fosamprenavir">Fosamprenavir (FPV)</a></li> <li><a href="/wiki/Indinavir" title="Indinavir">Indinavir (IDV)</a><sup>◊</sup></li> <li><a href="/wiki/Lopinavir" title="Lopinavir">Lopinavir (LPV)</a></li> <li><a href="/wiki/Nelfinavir" title="Nelfinavir">Nelfinavir (NFV)</a><sup>◊</sup></li> <li><a href="/wiki/Ritonavir" title="Ritonavir">Ritonavir (RTV)</a><sup>#</sup></li> <li><a href="/wiki/Saquinavir" title="Saquinavir">Saquinavir (SQV)</a><sup>◊</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">2<sup>nd</sup> generation</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Atazanavir" title="Atazanavir">Atazanavir (ATV)</a>°<sup>#</sup></li> <li><a href="/wiki/Darunavir" title="Darunavir">Darunavir (DRV)</a>°<sup>#</sup></li> <li><a href="/wiki/Tipranavir" title="Tipranavir">Tipranavir (TPV)</a><sup>◊</sup></li> <li><a href="/wiki/TMC-310911" title="TMC-310911">TMC-310911</a><sup>§</sup></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Reverse-transcriptase_inhibitor" title="Reverse-transcriptase inhibitor">Reverse-transcriptase<br /> inhibitors</a> (RTIs)</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Reverse-transcriptase_inhibitor" title="Reverse-transcriptase inhibitor">Nucleoside and<br /> nucleotide (NRTI)</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Nucleoside_analogue" title="Nucleoside analogue">Nucleoside analogues</a>/<a href="/wiki/Reverse-transcriptase_inhibitor#Nucleoside_analog_reverse-transcriptase_inhibitors_.28NARTIs_or_NRTIs.29" title="Reverse-transcriptase inhibitor">NRTIs</a>:</i> <a href="/wiki/Abacavir" title="Abacavir">Abacavir (ABC)</a><sup>#</sup></li> <li><a href="/wiki/Didanosine" title="Didanosine">Didanosine (ddI)</a><sup>◊</sup></li> <li><a href="/wiki/Emtricitabine" title="Emtricitabine">Emtricitabine (FTC)</a></li> <li><a href="/wiki/Lamivudine" title="Lamivudine">Lamivudine (3TC)</a><sup>#</sup></li> <li><a href="/wiki/Stavudine" title="Stavudine">Stavudine (d4T)</a><sup>◊</sup></li> <li><a href="/wiki/Zalcitabine" title="Zalcitabine">Zalcitabine (ddC)</a><sup>‡</sup></li> <li><a href="/wiki/Zidovudine" title="Zidovudine">Zidovudine (AZT, ZDV)</a><sup>#</sup></li> <li><a href="/wiki/Amdoxovir" title="Amdoxovir">Amdoxovir</a><sup>†</sup></li> <li><a href="/wiki/Apricitabine" title="Apricitabine">Apricitabine</a><sup>†</sup></li> <li><a href="/wiki/Censavudine" title="Censavudine">Censavudine</a><sup>†</sup></li> <li><a href="/wiki/Elvucitabine" title="Elvucitabine">Elvucitabine</a><sup>†</sup></li> <li><a href="/wiki/Islatravir" title="Islatravir">Islatravir (EFdA, ISL)</a><sup>§</sup></li> <li><a href="/wiki/Racivir" title="Racivir">Racivir</a><sup>†</sup></li> <li><a href="/wiki/Stampidine" title="Stampidine">Stampidine</a><sup>†</sup></li></ul> <ul><li><i><a href="/wiki/Nucleotide_analogue" class="mw-redirect" title="Nucleotide analogue">Nucleotide analogues</a>/<a href="/wiki/Reverse-transcriptase_inhibitor#Nucleotide_analog_reverse-transcriptase_inhibitors_.28NtARTIs_or_NtRTIs.29" title="Reverse-transcriptase inhibitor">NtRTIs</a>:</i> <a href="/wiki/Tenofovir_disoproxil" title="Tenofovir disoproxil">Tenofovir disoproxil (TDF)</a><sup>#</sup></li> <li><a href="/wiki/Tenofovir_alafenamide" title="Tenofovir alafenamide">Tenofovir alafenamide (TAF)</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Reverse-transcriptase_inhibitor#Non-nucleoside_reverse-transcriptase_inhibitors_(NNRTIs)" title="Reverse-transcriptase inhibitor">Non-nucleoside (NNRTI)</a><br /><i>(<a href="/wiki/Discovery_and_development_of_non-nucleoside_reverse-transcriptase_inhibitors" title="Discovery and development of non-nucleoside reverse-transcriptase inhibitors">Discovery and development</a>)</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">1<sup>st</sup> generation</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Efavirenz" title="Efavirenz">Efavirenz (EFV)</a><sup>#</sup></li> <li><a href="/wiki/Nevirapine" title="Nevirapine">Nevirapine (NVP)</a><sup>#</sup></li> <li><a href="/wiki/Delavirdine" title="Delavirdine">Delavirdine (DLV)</a><sup>‡</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">2<sup>nd</sup> generation</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Diarylpyrimidines" title="Diarylpyrimidines">diarylpyrimidines</a></i> <ul><li><a href="/wiki/Dapivirine" title="Dapivirine">Dapivirine (DPV)</a></li> <li><a href="/wiki/Etravirine" title="Etravirine">Etravirine (ETR)</a></li> <li><a href="/wiki/Rilpivirine" title="Rilpivirine">Rilpivirine (RPV)</a></li></ul></li> <li><a href="/wiki/Doravirine" title="Doravirine">Doravirine (DOR)</a></li> <li><a href="/wiki/Elsulfavirine" title="Elsulfavirine">Elsulfavirine (ESV)</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fixed-dose_combination_(antiretroviral)" class="mw-redirect" title="Fixed-dose combination (antiretroviral)">Combined formulations</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abacavir/lamivudine" title="Abacavir/lamivudine">Abacavir/lamivudine</a><sup>#</sup></li> <li><a href="/wiki/Abacavir/dolutegravir/lamivudine" title="Abacavir/dolutegravir/lamivudine">Abacavir/dolutegravir/lamivudine</a>°</li> <li><a href="/wiki/Abacavir/lamivudine/zidovudine" title="Abacavir/lamivudine/zidovudine">Abacavir/lamivudine/zidovudine</a></li> <li><a href="/wiki/Atazanavir/cobicistat" title="Atazanavir/cobicistat">Atazanavir/cobicistat</a></li> <li><a href="/wiki/Bictegravir/emtricitabine/tenofovir_alafenamide" title="Bictegravir/emtricitabine/tenofovir alafenamide">Bictegravir/emtricitabine/tenofovir alafenamide</a>°</li> <li><a href="/wiki/Cabotegravir/rilpivirine" title="Cabotegravir/rilpivirine">Cabotegravir/rilpivirine</a></li> <li><a href="/wiki/Darunavir/cobicistat" title="Darunavir/cobicistat">Darunavir/cobicistat</a></li> <li><a href="/wiki/Darunavir/cobicistat/emtricitabine/tenofovir_alafenamide" class="mw-redirect" title="Darunavir/cobicistat/emtricitabine/tenofovir alafenamide">Darunavir/cobicistat/emtricitabine/tenofovir alafenamide</a>°</li> <li><a href="/wiki/Dolutegravir/emtricitabine/tenofovir_alafenamide" class="mw-redirect" title="Dolutegravir/emtricitabine/tenofovir alafenamide">Dolutegravir/emtricitabine/tenofovir alafenamide</a></li> <li><a href="/wiki/Dolutegravir/lamivudine" title="Dolutegravir/lamivudine">Dolutegravir/lamivudine</a>°</li> <li><a href="/wiki/Dolutegravir/lamivudine/tenofovir_alafenamide" class="mw-redirect" title="Dolutegravir/lamivudine/tenofovir alafenamide">Dolutegravir/lamivudine/tenofovir alafenamide</a>°</li> <li><a href="/wiki/Dolutegravir/lamivudine/tenofovir_disoproxil" class="mw-redirect" title="Dolutegravir/lamivudine/tenofovir disoproxil">Dolutegravir/lamivudine/tenofovir disoproxil</a>°<sup>#</sup></li> <li><a href="/wiki/Dolutegravir/rilpivirine" title="Dolutegravir/rilpivirine">Dolutegravir/rilpivirine</a></li> <li><a href="/wiki/Doravirine/lamivudine/tenofovir_disoproxil" class="mw-redirect" title="Doravirine/lamivudine/tenofovir disoproxil">Doravirine/lamivudine/tenofovir disoproxil</a></li> <li><a href="/wiki/Efavirenz/emtricitabine/tenofovir_disoproxil" class="mw-redirect" title="Efavirenz/emtricitabine/tenofovir disoproxil">Efavirenz/emtricitabine/tenofovir disoproxil</a><sup>#</sup></li> <li><a href="/wiki/Efavirenz/lamivudine/tenofovir_disoproxil" class="mw-redirect" title="Efavirenz/lamivudine/tenofovir disoproxil">Efavirenz/lamivudine/tenofovir disoproxil</a><sup>#</sup></li> <li><a href="/wiki/Elvitegravir/cobicistat/emtricitabine/tenofovir_alafenamide" class="mw-redirect" title="Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide">Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide</a></li> <li><a href="/wiki/Elvitegravir/cobicistat/emtricitabine/tenofovir_disoproxil" class="mw-redirect" title="Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil">Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil</a></li> <li><a href="/wiki/Emtricitabine/tenofovir_alafenamide" class="mw-redirect" title="Emtricitabine/tenofovir alafenamide">Emtricitabine/tenofovir alafenamide</a></li> <li><a href="/wiki/Emtricitabine/rilpivirine/tenofovir_alafenamide" class="mw-redirect" title="Emtricitabine/rilpivirine/tenofovir alafenamide">Emtricitabine/rilpivirine/tenofovir alafenamide</a></li> <li><a href="/wiki/Emtricitabine/rilpivirine/tenofovir_disoproxil" class="mw-redirect" title="Emtricitabine/rilpivirine/tenofovir disoproxil">Emtricitabine/rilpivirine/tenofovir disoproxil</a></li> <li><a href="/wiki/Emtricitabine/tenofovir_disoproxil" class="mw-redirect" title="Emtricitabine/tenofovir disoproxil">Emtricitabine/tenofovir disoproxil</a><sup>#</sup></li> <li><a href="/wiki/Lamivudine/nevirapine/stavudine" title="Lamivudine/nevirapine/stavudine">Lamivudine/nevirapine/stavudine</a></li> <li><a href="/wiki/Lamivudine/nevirapine/zidovudine" title="Lamivudine/nevirapine/zidovudine">Lamivudine/nevirapine/zidovudine</a></li> <li><a href="/wiki/Lamivudine/raltegravir" title="Lamivudine/raltegravir">Lamivudine/raltegravir</a></li> <li><a href="/wiki/Lamivudine/tenofovir_disoproxil" class="mw-redirect" title="Lamivudine/tenofovir disoproxil">Lamivudine/tenofovir disoproxil</a><sup>#</sup></li> <li><a href="/wiki/Lamivudine/zidovudine" title="Lamivudine/zidovudine">Lamivudine/zidovudine</a><sup>#</sup></li> <li><a href="/wiki/Lopinavir/ritonavir" title="Lopinavir/ritonavir">Lopinavir/ritonavir</a><sup>#</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Pharmacokinetic boosters</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cobicistat" title="Cobicistat">Cobicistat (c)</a></li> <li><a href="/wiki/Ritonavir" title="Ritonavir">Ritonavir (r)</a><sup>#</sup></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Experimental agents</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Antiviral_drug#Uncoating_inhibitor" title="Antiviral drug">Uncoating inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/TRIM5alpha" title="TRIM5alpha">TRIM5alpha</a> (gene)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Transcription_(genetics)" class="mw-redirect" title="Transcription (genetics)">Transcription inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Tat_(HIV)#Clinical_significance" title="Tat (HIV)">Tat antagonists</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Antiviral_drug#Translation_.2F_ribozymes" title="Antiviral drug">Translation inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Trichosanthin" title="Trichosanthin">Trichosanthin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Antiviral_drug#BNAbs.2F_BNAbs" title="Antiviral drug"> BNAbs</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Elipovimab" title="Elipovimab">Elipovimab</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abzyme" title="Abzyme">Abzyme</a></li> <li><a href="/wiki/BIT225" title="BIT225">BIT225</a><sup>†</sup></li> <li><a href="/wiki/Calanolide_A" title="Calanolide A">Calanolide A</a></li> <li><a href="/wiki/Ceragenin" title="Ceragenin">Ceragenin</a></li> <li><a href="/wiki/Cyanovirin-N" title="Cyanovirin-N">Cyanovirin-N</a></li> <li><a href="/wiki/Diarylpyrimidines" title="Diarylpyrimidines">Diarylpyrimidines</a></li> <li><a href="/wiki/Epigallocatechin_gallate" title="Epigallocatechin gallate">Epigallocatechin gallate (EGCG)</a></li> <li><a href="/wiki/Foscarnet" title="Foscarnet">Foscarnet</a></li> <li><a href="/wiki/Fosdevirine" title="Fosdevirine">Fosdevirine</a><sup>†</sup></li> <li><a href="/wiki/Griffithsin" title="Griffithsin">Griffithsin</a></li> <li><a href="/wiki/Hydroxycarbamide" title="Hydroxycarbamide">Hydroxycarbamide</a></li> <li><a href="/wiki/KP-1461" title="KP-1461">KP-1461</a><sup>†</sup></li> <li><a href="/wiki/Miltefosine" title="Miltefosine">Miltefosine</a></li> <li><a href="/wiki/Portmanteau_inhibitor" title="Portmanteau inhibitor">Portmanteau inhibitors</a></li> <li><a href="/wiki/Scytovirin" title="Scytovirin">Scytovirin</a></li> <li><a href="/wiki/Seliciclib" title="Seliciclib">Seliciclib</a><sup>†</sup></li> <li><a href="/wiki/Synergistic_enhancer_(antiretroviral)" title="Synergistic enhancer (antiretroviral)">Synergistic enhancers</a></li> <li><a href="/wiki/Tre_recombinase" title="Tre recombinase">Tre recombinase</a></li> <li><a href="/wiki/Zinc_finger_protein_transcription_factor" class="mw-redirect" title="Zinc finger protein transcription factor">Zinc finger protein transcription factor</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Failed agents</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aplaviroc" title="Aplaviroc">Aplaviroc</a></li> <li><a href="/wiki/Atevirdine" title="Atevirdine">Atevirdine</a></li> <li><a href="/wiki/Brecanavir" title="Brecanavir">Brecanavir</a></li> <li><a href="/wiki/Capravirine" title="Capravirine">Capravirine</a></li> <li><a href="/wiki/Dexelvucitabine" title="Dexelvucitabine">Dexelvucitabine</a></li> <li><a href="/wiki/Droxinavir" title="Droxinavir">Droxinavir</a></li> <li><a class="mw-selflink selflink">Lasinavir</a></li> <li><a href="/wiki/Emivirine" title="Emivirine">Emivirine</a></li> <li><a href="/wiki/Lersivirine" class="mw-redirect" title="Lersivirine">Lersivirine</a></li> <li><a href="/wiki/Lodenosine" title="Lodenosine">Lodenosine</a></li> <li><a href="/wiki/Loviride" title="Loviride">Loviride</a></li> <li><a href="/wiki/Mozenavir" title="Mozenavir">Mozenavir</a></li> <li><a href="/w/index.php?title=Palinavir&action=edit&redlink=1" class="new" title="Palinavir (page does not exist)">Palinavir</a></li> <li><a href="/w/index.php?title=Telinavir&action=edit&redlink=1" class="new" title="Telinavir (page does not exist)">Telinavir</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><div class="hlist"> <ul><li><sup>#</sup><a href="/wiki/WHO_Model_List_of_Essential_Medicines" title="WHO Model List of Essential Medicines">WHO-EM</a></li> <li><sup>‡</sup><a href="/wiki/List_of_withdrawn_drugs" title="List of withdrawn drugs">Withdrawn</a> from market</li> <li><a href="/wiki/Clinical_trial" title="Clinical trial">Clinical trials</a>: <ul><li><sup>†</sup><a href="/wiki/Phases_of_clinical_research#Phase_III" title="Phases of clinical research">Phase III</a></li> <li><sup>§</sup>Never to phase III</li></ul></li></ul> </div> °<a href="/wiki/United_States_Department_of_Health_and_Human_Services" title="United States Department of Health and Human Services">DHHS</a> <i>recommended</i> <a href="/wiki/Therapy#Lines_of_therapy" title="Therapy">initial regimen options</a>. <sup>◊</sup>Formerly or rarely used agent.<br /></div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r1012311289">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a 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