Cancer Science & Therapy | Volume 4, Issue 1

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class="col-sm"> <h3 class="text-primary font-size-6 my-3 border-bottom-2 border-yellow-900 pb-2">Volume 4, Issue 1 (2012)</h2> <div class="border-bottom-1 py-2"> <div class="d-flex w-100 justify-content-between mb-1"> <span class="align-self-center"> Editorial </span> <span class="w-25 ml-4 text-right"> Pages: 1 - 2 </span> </div> <h3 class="mb-2 font-size-4"><a href="https://www.hilarispublisher.com/open-access/cancer-nanotechnology-1948-5956.1000e104.pdf" title="Cancer Nanotechnology">Cancer Nanotechnology</a></h3> <p class="mb-2 font-size-3 text-muted"> <i class="fas fa-user"></i> <a href='https://www.hilarispublisher.com/author-profile/jagat-r-kanwar-434489' style='color:#555; border-bottom:1px dotted #CCC;' title='Jagat R. Kanwar'>Jagat R. Kanwar</a> </p> <p class="mb-1 font-size-3 text-muted">DOI: <a href="https://doi.org/10.4172/1948-5956.1000e104" title="Click here">10.4172/1948-5956.1000e104</a></p> <div class="row justify-content-between align-items-center"> <div class="col-sm-auto"> <nav class="nav a-mx-2"> <a href="https://www.hilarispublisher.com/open-access/cancer-nanotechnology-1948-5956.1000e104.pdf" title="PDF" class="card-link border-bottom-2 border-blue-900"><i class="fas fa-file-pdf fa-lg"></i> PDF</a> </nav> </div> <div class="col-sm-auto"> <div class="d-flex align-items-center"> Share this article <nav class="nav a-px-2 a-share-icons ml-3"> <a href="https://www.facebook.com/sharer.php?u=https://www.hilarispublisher.com/open-access/cancer-nanotechnology-1948-5956.1000e104.pdf" class="nav-link" target="_blank"><i class="fab fa-facebook-f facebook"></i></a> <a href="https://twitter.com/share?url=https://www.hilarispublisher.com/open-access/cancer-nanotechnology-1948-5956.1000e104.pdf" class="nav-link" target="_blank"><i class="fab fa-twitter twitter"></i></a> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.hilarispublisher.com/open-access/cancer-nanotechnology-1948-5956.1000e104.pdf" class="nav-link" target="_blank"><i class="fab fa-linkedin-in linkedin"></i></a> <a href="https://pinterest.com/pin/create/button/?url=https://www.hilarispublisher.com/open-access/cancer-nanotechnology-1948-5956.1000e104.pdf" class="nav-link" target="_blank"><i class="fab fa-pinterest-p pinterest"></i></a> <a href="https://www.blogger.com/blog-this.g?u=https://www.hilarispublisher.com/open-access/cancer-nanotechnology-1948-5956.1000e104.pdf" class="nav-link" target="_blank"><i class="fab fa-blogger-b blogger"></i></a> </nav> </div> </div> </div> <div class="collapse" id="collapseAbstract38721"> <div class="card card-body p-2 bg-light"></div> </div> </div> <div class="border-bottom-1 py-2"> <div class="d-flex w-100 justify-content-between mb-1"> <span class="align-self-center"> Editorial </span> <span class="w-25 ml-4 text-right"> Pages: 1 - 1 </span> </div> <h3 class="mb-2 font-size-4"><a href="https://www.hilarispublisher.com/open-access/enabling-oral-cancer-translational-research-in-india-1948-5956.1000e103.pdf" title="Enabling Oral Cancer Translational Research in India">Enabling Oral Cancer Translational Research in India</a></h3> <p class="mb-2 font-size-3 text-muted"> <i class="fas fa-user"></i> <a href='https://www.hilarispublisher.com/author-profile/prakash-s-bisen-434487' style='color:#555; border-bottom:1px dotted #CCC;' title='Prakash S Bisen'>Prakash S Bisen</a> </p> <p class="mb-1 font-size-3 text-muted">DOI: <a href="https://doi.org/10.4172/1948-5956.1000e103" title="Click here">10.4172/1948-5956.1000e103</a></p> <div class="row justify-content-between align-items-center"> <div class="col-sm-auto"> <nav class="nav a-mx-2"> <a href="https://www.hilarispublisher.com/open-access/enabling-oral-cancer-translational-research-in-india-1948-5956.1000e103.pdf" title="PDF" class="card-link border-bottom-2 border-blue-900"><i class="fas fa-file-pdf fa-lg"></i> PDF</a> </nav> </div> <div class="col-sm-auto"> <div class="d-flex align-items-center"> Share this article <nav class="nav a-px-2 a-share-icons ml-3"> <a href="https://www.facebook.com/sharer.php?u=https://www.hilarispublisher.com/open-access/enabling-oral-cancer-translational-research-in-india-1948-5956.1000e103.pdf" class="nav-link" target="_blank"><i class="fab fa-facebook-f facebook"></i></a> <a href="https://twitter.com/share?url=https://www.hilarispublisher.com/open-access/enabling-oral-cancer-translational-research-in-india-1948-5956.1000e103.pdf" class="nav-link" target="_blank"><i class="fab fa-twitter twitter"></i></a> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.hilarispublisher.com/open-access/enabling-oral-cancer-translational-research-in-india-1948-5956.1000e103.pdf" class="nav-link" target="_blank"><i class="fab fa-linkedin-in linkedin"></i></a> <a href="https://pinterest.com/pin/create/button/?url=https://www.hilarispublisher.com/open-access/enabling-oral-cancer-translational-research-in-india-1948-5956.1000e103.pdf" class="nav-link" target="_blank"><i class="fab fa-pinterest-p pinterest"></i></a> <a href="https://www.blogger.com/blog-this.g?u=https://www.hilarispublisher.com/open-access/enabling-oral-cancer-translational-research-in-india-1948-5956.1000e103.pdf" class="nav-link" target="_blank"><i class="fab fa-blogger-b blogger"></i></a> </nav> </div> </div> </div> <div class="collapse" id="collapseAbstract38706"> <div class="card card-body p-2 bg-light"></div> </div> </div> <div class="border-bottom-1 py-2"> <div class="d-flex w-100 justify-content-between mb-1"> <span class="align-self-center"> Research Article </span> <span class="w-25 ml-4 text-right"> Pages: 1 - 3 </span> </div> <h3 class="mb-2 font-size-4"><a href="https://www.hilarispublisher.com/open-access/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-1948-5956.1000100.pdf" title="Appling Genetic Algorithm to Optimize Locations and Activities of the Seeds in Brachytherapy to Deliver Dose to the Defined Border">Appling Genetic Algorithm to Optimize Locations and Activities of the Seeds in Brachytherapy to Deliver Dose to the Defined Border</a></h3> <p class="mb-2 font-size-3 text-muted"> <i class="fas fa-user"></i> <a href='https://www.hilarispublisher.com/author-profile/mowlavi-aa-434490' style='color:#555; border-bottom:1px dotted #CCC;' title='Mowlavi AA '>Mowlavi AA</a>, <a href='https://www.hilarispublisher.com/author-profile/zibandehgorji-m-434491' style='color:#555; border-bottom:1px dotted #CCC;' title='Zibandeh-Gorji M '>Zibandeh-Gorji M</a> and <a href='https://www.hilarispublisher.com/author-profile/mohammadi-s-434492' style='color:#555; border-bottom:1px dotted #CCC;' title='Mohammadi S '>Mohammadi S</a> </p> <p class="mb-1 font-size-3 text-muted">DOI: <a href="https://doi.org/10.4172/1948-5956.1000100" title="Click here">10.4172/1948-5956.1000100</a></p> <div class="row justify-content-between align-items-center"> <div class="col pl-0"> <a class="btn btn-link" data-toggle="collapse" href="#collapseAbstract38704" role="button" aria-expanded="false" aria-controls="collapseAbstract"> Preview Abstract </a> </div> <div class="col-sm-auto"> <nav class="nav a-mx-2"> <a href="https://www.hilarispublisher.com/abstract/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-to-deliver-dose-to-the-defi-38704.html" title="Abstract" class="card-link border-bottom-2 yellow-900 border-yellow-900"><i class="fas fa-file-alt fa-lg"></i> Abstract</a> <a href="https://www.hilarispublisher.com/open-access/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-1948-5956.1000100.pdf" title="PDF" class="card-link border-bottom-2 border-blue-900"><i class="fas fa-file-pdf fa-lg"></i> PDF</a> </nav> </div> <div class="col-sm-auto"> <div class="d-flex align-items-center"> Share this article <nav class="nav a-px-2 a-share-icons ml-3"> <a href="https://www.facebook.com/sharer.php?u=https://www.hilarispublisher.com/open-access/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-1948-5956.1000100.pdf" class="nav-link" target="_blank"><i class="fab fa-facebook-f facebook"></i></a> <a href="https://twitter.com/share?url=https://www.hilarispublisher.com/open-access/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-1948-5956.1000100.pdf" class="nav-link" target="_blank"><i class="fab fa-twitter twitter"></i></a> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.hilarispublisher.com/open-access/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-1948-5956.1000100.pdf" class="nav-link" target="_blank"><i class="fab fa-linkedin-in linkedin"></i></a> <a href="https://pinterest.com/pin/create/button/?url=https://www.hilarispublisher.com/open-access/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-1948-5956.1000100.pdf" class="nav-link" target="_blank"><i class="fab fa-pinterest-p pinterest"></i></a> <a href="https://www.blogger.com/blog-this.g?u=https://www.hilarispublisher.com/open-access/appling-genetic-algorithm-to-optimize-locations-and-activities-of-the-seeds-in-brachytherapy-1948-5956.1000100.pdf" class="nav-link" target="_blank"><i class="fab fa-blogger-b blogger"></i></a> </nav> </div> </div> </div> <div class="collapse" id="collapseAbstract38704"> <div class="card card-body p-2 bg-light"><p>As it is well known, improving in treatment planning of brachytherapy is very important. In this research, we have introduced a method for this purpose. We have applied the genetic algorithm to find the proper locations and activities of a 125I brachytherapy seeds to deliver a desired dose to the border of the tumor in two dimensional surfaces. The initial positions of the seeds have been identified, and then by using a MATLAB code based on the genetic algorithm, we obtained the best locations and the activities of the seeds. This optimization method has been applied for some shape of the tumors. The results show that the desired dose to the border of a square, ellipsoid and general form of tumors is matched very well.</p> <p>According to the results this technique can be used to optimize treatment plan of brachytherapy usefully. We plan to extend this method for three dimensional situations.</p> <p> </p></div> </div> </div> <div class="border-bottom-1 py-2"> <div class="d-flex w-100 justify-content-between mb-1"> <span class="align-self-center"> Case Report </span> <span class="w-25 ml-4 text-right"> Pages: 1 - 2 </span> </div> <h3 class="mb-2 font-size-4"><a href="https://www.hilarispublisher.com/open-access/symptomatic-renal-metastasis-of-osteosarcoma-occurring-after-7-years-of-complete-remission-a-case-report-1948-5956.1000101.pdf" title="Symptomatic Renal Metastasis of Osteosarcoma Occurring after 7 Years of Complete Remission: A Case Report">Symptomatic Renal Metastasis of Osteosarcoma Occurring after 7 Years of Complete Remission: A Case Report</a></h3> <p class="mb-2 font-size-3 text-muted"> <i class="fas fa-user"></i> <a href='https://www.hilarispublisher.com/author-profile/bennani-anas-434592' style='color:#555; border-bottom:1px dotted #CCC;' title='Bennani Anas '>Bennani Anas</a>, <a href='https://www.hilarispublisher.com/author-profile/oualla-k-434593' style='color:#555; border-bottom:1px dotted #CCC;' title='Oualla K '>Oualla K</a>, <a href='https://www.hilarispublisher.com/author-profile/badioui-i-434594' style='color:#555; border-bottom:1px dotted #CCC;' title='Badioui I '>Badioui I</a>, <a href='https://www.hilarispublisher.com/author-profile/lahrach-k-434595' style='color:#555; border-bottom:1px dotted #CCC;' title='Lahrach K '>Lahrach K</a>, <a href='https://www.hilarispublisher.com/author-profile/hamdi-o-434597' style='color:#555; border-bottom:1px dotted #CCC;' title='Hamdi O '>Hamdi O</a>, <a href='https://www.hilarispublisher.com/author-profile/almoubaker-s-434598' style='color:#555; border-bottom:1px dotted #CCC;' title='Almoubaker S '>Almoubaker S</a>, <a href='https://www.hilarispublisher.com/author-profile/marzouki-a-434599' style='color:#555; border-bottom:1px dotted #CCC;' title='Marzouki A '>Marzouki A</a>, <a href='https://www.hilarispublisher.com/author-profile/el-mesbahi-o-434600' style='color:#555; border-bottom:1px dotted #CCC;' title='El Mesbahi O '>El Mesbahi O</a>, <a href='https://www.hilarispublisher.com/author-profile/rifi-amarti-a-434601' style='color:#555; border-bottom:1px dotted #CCC;' title='Rifi Amarti A '>Rifi Amarti A</a> and <a href='https://www.hilarispublisher.com/author-profile/boutayeb-f-434602' style='color:#555; border-bottom:1px dotted #CCC;' title='Boutayeb F '>Boutayeb F</a> </p> <p class="mb-1 font-size-3 text-muted">DOI: <a href="https://doi.org/10.4172/1948-5956.1000101" title="Click here">10.4172/1948-5956.1000101</a></p> <div class="row justify-content-between align-items-center"> <div class="col-sm-auto"> <nav class="nav a-mx-2"> <a href="https://www.hilarispublisher.com/open-access/symptomatic-renal-metastasis-of-osteosarcoma-occurring-after-7-years-of-complete-remission-a-case-report-1948-5956.1000101.pdf" title="PDF" class="card-link border-bottom-2 border-blue-900"><i class="fas fa-file-pdf fa-lg"></i> PDF</a> </nav> </div> <div class="col-sm-auto"> <div class="d-flex align-items-center"> Share this article <nav class="nav a-px-2 a-share-icons ml-3"> <a href="https://www.facebook.com/sharer.php?u=https://www.hilarispublisher.com/open-access/symptomatic-renal-metastasis-of-osteosarcoma-occurring-after-7-years-of-complete-remission-a-case-report-1948-5956.1000101.pdf" class="nav-link" target="_blank"><i class="fab fa-facebook-f facebook"></i></a> <a href="https://twitter.com/share?url=https://www.hilarispublisher.com/open-access/symptomatic-renal-metastasis-of-osteosarcoma-occurring-after-7-years-of-complete-remission-a-case-report-1948-5956.1000101.pdf" class="nav-link" target="_blank"><i class="fab fa-twitter twitter"></i></a> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.hilarispublisher.com/open-access/symptomatic-renal-metastasis-of-osteosarcoma-occurring-after-7-years-of-complete-remission-a-case-report-1948-5956.1000101.pdf" class="nav-link" target="_blank"><i class="fab fa-linkedin-in linkedin"></i></a> <a href="https://pinterest.com/pin/create/button/?url=https://www.hilarispublisher.com/open-access/symptomatic-renal-metastasis-of-osteosarcoma-occurring-after-7-years-of-complete-remission-a-case-report-1948-5956.1000101.pdf" class="nav-link" target="_blank"><i class="fab fa-pinterest-p pinterest"></i></a> <a href="https://www.blogger.com/blog-this.g?u=https://www.hilarispublisher.com/open-access/symptomatic-renal-metastasis-of-osteosarcoma-occurring-after-7-years-of-complete-remission-a-case-report-1948-5956.1000101.pdf" class="nav-link" target="_blank"><i class="fab fa-blogger-b blogger"></i></a> </nav> </div> </div> </div> <div class="collapse" id="collapseAbstract38705"> <div class="card card-body p-2 bg-light"></div> </div> </div> <div class="border-bottom-1 py-2"> <div class="d-flex w-100 justify-content-between mb-1"> <span class="align-self-center"> Research Article </span> <span class="w-25 ml-4 text-right"> Pages: 1 - 4 </span> </div> <h3 class="mb-2 font-size-4"><a href="https://www.hilarispublisher.com/open-access/effects-of-quercetin-induced-cell-death-on-a-novel-gene-urgurgcp-expression-in-leukemia-cells-1948-5956.1000102.pdf" title="Effects of Quercetin Induced Cell Death on a Novel Gene "<em>URG4/URGCP</em>" Expression in Leukemia Cells">Effects of Quercetin Induced Cell Death on a Novel Gene "<em>URG4/URGCP</em>" Expression in Leukemia Cells</a></h3> <p class="mb-2 font-size-3 text-muted"> <i class="fas fa-user"></i> <a href='https://www.hilarispublisher.com/author-profile/yavuz-dodurga-434609' style='color:#555; border-bottom:1px dotted #CCC;' title='Yavuz Dodurga '>Yavuz Dodurga</a>, <a href='https://www.hilarispublisher.com/author-profile/cigir-biray-avci-434610' style='color:#555; border-bottom:1px dotted #CCC;' title='Cigir Biray Avci '>Cigir Biray Avci</a>, <a href='https://www.hilarispublisher.com/author-profile/lale-satiroglutufan-n-434611' style='color:#555; border-bottom:1px dotted #CCC;' title='Lale Satiroglu-Tufan N '>Lale Satiroglu-Tufan N</a>, <a href='https://www.hilarispublisher.com/author-profile/sunde-yilmaz-susluer-434612' style='color:#555; border-bottom:1px dotted #CCC;' title='Sunde Yilmaz Susluer '>Sunde Yilmaz Susluer</a>, <a href='https://www.hilarispublisher.com/author-profile/ozlem-dogan-sigva-z-434613' style='color:#555; border-bottom:1px dotted #CCC;' title='Ozlem Dogan Sigva Z '>Ozlem Dogan Sigva Z</a>, <a href='https://www.hilarispublisher.com/author-profile/guray-saydam-434614' style='color:#555; border-bottom:1px dotted #CCC;' title='Guray Saydam '>Guray Saydam</a> and <a href='https://www.hilarispublisher.com/author-profile/cumhur-gunduz-434615' style='color:#555; border-bottom:1px dotted #CCC;' title='Cumhur Gunduz '>Cumhur Gunduz</a> </p> <p class="mb-1 font-size-3 text-muted">DOI: <a href="https://doi.org/10.4172/1948-5956.1000102" title="Click here">10.4172/1948-5956.1000102</a></p> <div class="row justify-content-between align-items-center"> <div class="col pl-0"> <a class="btn btn-link" data-toggle="collapse" href="#collapseAbstract38707" role="button" aria-expanded="false" aria-controls="collapseAbstract"> Preview Abstract </a> </div> <div class="col-sm-auto"> <nav class="nav a-mx-2"> <a href="https://www.hilarispublisher.com/abstract/effects-of-quercetin-induced-cell-death-on-a-novel-gene-quotemurg4urgcpemquot-expression-in-leukemia-cells-38707.html" title="Abstract" class="card-link border-bottom-2 yellow-900 border-yellow-900"><i class="fas fa-file-alt fa-lg"></i> Abstract</a> <a href="https://www.hilarispublisher.com/open-access/effects-of-quercetin-induced-cell-death-on-a-novel-gene-urgurgcp-expression-in-leukemia-cells-1948-5956.1000102.pdf" title="PDF" class="card-link border-bottom-2 border-blue-900"><i class="fas fa-file-pdf fa-lg"></i> PDF</a> </nav> </div> <div class="col-sm-auto"> <div class="d-flex align-items-center"> Share this article <nav class="nav a-px-2 a-share-icons ml-3"> <a href="https://www.facebook.com/sharer.php?u=https://www.hilarispublisher.com/open-access/effects-of-quercetin-induced-cell-death-on-a-novel-gene-urgurgcp-expression-in-leukemia-cells-1948-5956.1000102.pdf" class="nav-link" target="_blank"><i class="fab fa-facebook-f facebook"></i></a> <a href="https://twitter.com/share?url=https://www.hilarispublisher.com/open-access/effects-of-quercetin-induced-cell-death-on-a-novel-gene-urgurgcp-expression-in-leukemia-cells-1948-5956.1000102.pdf" class="nav-link" target="_blank"><i class="fab fa-twitter twitter"></i></a> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.hilarispublisher.com/open-access/effects-of-quercetin-induced-cell-death-on-a-novel-gene-urgurgcp-expression-in-leukemia-cells-1948-5956.1000102.pdf" class="nav-link" target="_blank"><i class="fab fa-linkedin-in linkedin"></i></a> <a href="https://pinterest.com/pin/create/button/?url=https://www.hilarispublisher.com/open-access/effects-of-quercetin-induced-cell-death-on-a-novel-gene-urgurgcp-expression-in-leukemia-cells-1948-5956.1000102.pdf" class="nav-link" target="_blank"><i class="fab fa-pinterest-p pinterest"></i></a> <a href="https://www.blogger.com/blog-this.g?u=https://www.hilarispublisher.com/open-access/effects-of-quercetin-induced-cell-death-on-a-novel-gene-urgurgcp-expression-in-leukemia-cells-1948-5956.1000102.pdf" class="nav-link" target="_blank"><i class="fab fa-blogger-b blogger"></i></a> </nav> </div> </div> </div> <div class="collapse" id="collapseAbstract38707"> <div class="card card-body p-2 bg-light"><p>The present study aimed to investigate anti-proliferative and apoptotic effects of quercetin on human leukemia cells and effects of quercetin-induced cell death on a novel gene Up-regulated gene 4/upregulator of cell proliferation ( URG4/URGCP ), in leukemia cells. URG4/URGCP expression is determined by using RT-PCR. IC 50 of quercetin was determined as 25 microM in CCRF-CEM, HL–60 and K562 cells. In IC 50 dose group, URG4/URGCP expression was decreased 99% in HL-60 cells, 90% in CCRF-CEM cells, and 52% (24 hour) - 99% (72 hour) in K-562 cells. URG4/URGCP may play important roles in the development of leukemia, and might be a useful molecular marker for predicting the prognosis of leukemia via quercetin treatment.</p> <p> </p></div> </div> </div> </div> <div class="col-12 col-sm-3">    <div class="mb-3"> <h4><a href="https://www.hilarispublisher.com/cancer-science-therapy/awards-nomination.html" class="btn btn-danger btn-block mb-3 font-size-4">Awards & Nominations</a></h4> <h4><a href="https://www.hilarispublisher.com/cancer-science-therapy-online-visitors-readers-89.html" class="btn btn-danger btn-block mb-3 font-size-4"><i class="fas fa-book-reader"></i> 50+ Million Readerbase</a></h4> <h4>Journal Highlights</h4> <nav class="nav flex-column scrollbar a-pl-0" style="max-height:50vh;"> <a href="https://www.hilarispublisher.com/scholarly/advances-in-alternative-lung-cancer-treatment-journals-articles-ppts-list-2298.html" class="nav-link" title="Advances in Alternative Lung Cancer Treatment"><i class="far 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Cancer Science & Therapy | Volume 4, Issue 1 | 2012