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class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Applications"> <div class="vector-toc-text"> 4 Applications </div> </a> <button aria-controls="toc-Applications-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> Toggle Applications subsection </button> <ul id="toc-Applications-sublist" class="vector-toc-list"> <li id="toc-Medicine" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Medicine"> <div class="vector-toc-text"> 4.1 Medicine </div> </a> <ul id="toc-Medicine-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Research" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Research"> <div class="vector-toc-text"> 4.2 Research </div> </a> <ul id="toc-Research-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Industrial" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Industrial"> <div class="vector-toc-text"> 4.3 Industrial </div> </a> <ul id="toc-Industrial-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Agriculture" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Agriculture"> <div class="vector-toc-text"> 4.4 Agriculture </div> </a> <ul id="toc-Agriculture-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Other_applications" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Other_applications"> <div class="vector-toc-text"> 4.5 Other applications </div> </a> <ul id="toc-Other_applications-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Regulation" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Regulation"> <div class="vector-toc-text"> 5 Regulation </div> </a> <ul id="toc-Regulation-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Controversy" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Controversy"> <div class="vector-toc-text"> 6 Controversy </div> </a> <ul id="toc-Controversy-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-In_popular_culture" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#In_popular_culture"> <div class="vector-toc-text"> 7 In popular culture </div> </a> <ul id="toc-In_popular_culture-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> 8 See also </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> 9 References </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> 10 Further reading </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> 11 External links </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" > Toggle the table of contents </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading">Genetic engineering</h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 87 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-87" aria-hidden="true" > 87 languages </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-af mw-list-item"><a href="https://af.wikipedia.org/wiki/Genetiese_manipulasie" title="Genetiese manipulasie – Afrikaans" lang="af" hreflang="af" data-title="Genetiese manipulasie" data-language-autonym="Afrikaans" data-language-local-name="Afrikaans" class="interlanguage-link-target">Afrikaans</a></li><li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%87%D9%86%D8%AF%D8%B3%D8%A9_%D9%88%D8%B1%D8%A7%D8%AB%D9%8A%D8%A9" title="هندسة وراثية – Arabic" lang="ar" hreflang="ar" data-title="هندسة وراثية" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target">العربية</a></li><li class="interlanguage-link interwiki-ast mw-list-item"><a href="https://ast.wikipedia.org/wiki/Inxenier%C3%ADa_xen%C3%A9tica" title="Inxeniería xenética – Asturian" lang="ast" hreflang="ast" data-title="Inxeniería xenética" data-language-autonym="Asturianu" data-language-local-name="Asturian" class="interlanguage-link-target">Asturianu</a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/Genetik_m%C3%BCh%C9%99ndisliyi" title="Genetik mühəndisliyi – Azerbaijani" lang="az" hreflang="az" data-title="Genetik mühəndisliyi" data-language-autonym="Azərbaycanca" data-language-local-name="Azerbaijani" class="interlanguage-link-target">Azərbaycanca</a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%AC%E0%A6%82%E0%A6%B6%E0%A6%BE%E0%A6%A3%E0%A7%81_%E0%A6%AA%E0%A7%8D%E0%A6%B0%E0%A6%95%E0%A7%8C%E0%A6%B6%E0%A6%B2" title="বংশাণু প্রকৌশল – Bangla" lang="bn" hreflang="bn" data-title="বংশাণু প্রকৌশল" data-language-autonym="বাংলা" data-language-local-name="Bangla" class="interlanguage-link-target">বাংলা</a></li><li class="interlanguage-link interwiki-ba mw-list-item"><a href="https://ba.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D0%BA_%D0%B8%D0%BD%D0%B6%D0%B5%D0%BD%D0%B5%D1%80%D0%B8%D1%8F" title="Генетик инженерия – Bashkir" lang="ba" hreflang="ba" data-title="Генетик инженерия" data-language-autonym="Башҡортса" data-language-local-name="Bashkir" class="interlanguage-link-target">Башҡортса</a></li><li class="interlanguage-link interwiki-be mw-list-item"><a href="https://be.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D1%8B%D1%87%D0%BD%D0%B0%D1%8F_%D1%96%D0%BD%D0%B6%D1%8B%D0%BD%D0%B5%D1%80%D1%8B%D1%8F" title="Генетычная інжынерыя – Belarusian" lang="be" hreflang="be" data-title="Генетычная інжынерыя" data-language-autonym="Беларуская" data-language-local-name="Belarusian" class="interlanguage-link-target">Беларуская</a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%BD%D0%BE_%D0%B8%D0%BD%D0%B6%D0%B5%D0%BD%D0%B5%D1%80%D1%81%D1%82%D0%B2%D0%BE" title="Генно инженерство – Bulgarian" lang="bg" hreflang="bg" data-title="Генно инженерство" data-language-autonym="Български" data-language-local-name="Bulgarian" class="interlanguage-link-target">Български</a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Geneti%C4%8Dko_in%C5%BEenjerstvo" title="Genetičko inženjerstvo – Bosnian" lang="bs" hreflang="bs" data-title="Genetičko inženjerstvo" data-language-autonym="Bosanski" data-language-local-name="Bosnian" class="interlanguage-link-target">Bosanski</a></li><li class="interlanguage-link interwiki-br mw-list-item"><a href="https://br.wikipedia.org/wiki/Teknologiezh_c%27henetek" title="Teknologiezh c'henetek – Breton" lang="br" hreflang="br" data-title="Teknologiezh c'henetek" data-language-autonym="Brezhoneg" data-language-local-name="Breton" class="interlanguage-link-target">Brezhoneg</a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Enginyeria_gen%C3%A8tica" title="Enginyeria genètica – Catalan" lang="ca" hreflang="ca" data-title="Enginyeria genètica" data-language-autonym="Català" data-language-local-name="Catalan" class="interlanguage-link-target">Català</a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Genetick%C3%A9_in%C5%BEen%C3%BDrstv%C3%AD" title="Genetické inženýrství – Czech" lang="cs" hreflang="cs" data-title="Genetické inženýrství" data-language-autonym="Čeština" data-language-local-name="Czech" class="interlanguage-link-target">Čeština</a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Genteknologi" title="Genteknologi – Danish" lang="da" hreflang="da" data-title="Genteknologi" data-language-autonym="Dansk" data-language-local-name="Danish" class="interlanguage-link-target">Dansk</a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Gentechnik" title="Gentechnik – German" lang="de" hreflang="de" data-title="Gentechnik" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target">Deutsch</a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Geenitehnoloogia" title="Geenitehnoloogia – Estonian" lang="et" hreflang="et" data-title="Geenitehnoloogia" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target">Eesti</a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%93%CE%B5%CE%BD%CE%B5%CF%84%CE%B9%CE%BA%CE%AE_%CE%BC%CE%B7%CF%87%CE%B1%CE%BD%CE%B9%CE%BA%CE%AE" title="Γενετική μηχανική – Greek" lang="el" hreflang="el" data-title="Γενετική μηχανική" data-language-autonym="Ελληνικά" data-language-local-name="Greek" class="interlanguage-link-target">Ελληνικά</a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Ingenier%C3%ADa_gen%C3%A9tica" title="Ingeniería genética – Spanish" lang="es" hreflang="es" data-title="Ingeniería genética" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target">Español</a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Gentekniko" title="Gentekniko – Esperanto" lang="eo" hreflang="eo" data-title="Gentekniko" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target">Esperanto</a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Ingeniaritza_genetiko" title="Ingeniaritza genetiko – Basque" lang="eu" hreflang="eu" data-title="Ingeniaritza genetiko" data-language-autonym="Euskara" data-language-local-name="Basque" class="interlanguage-link-target">Euskara</a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%85%D9%87%D9%86%D8%AF%D8%B3%DB%8C_%DA%98%D9%86%D8%AA%DB%8C%DA%A9" title="مهندسی ژنتیک – Persian" lang="fa" hreflang="fa" data-title="مهندسی ژنتیک" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target">فارسی</a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/G%C3%A9nie_g%C3%A9n%C3%A9tique" title="Génie génétique – French" lang="fr" hreflang="fr" data-title="Génie génétique" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target">Français</a></li><li class="interlanguage-link interwiki-fy mw-list-item"><a href="https://fy.wikipedia.org/wiki/Genetyske_technology" title="Genetyske technology – Western Frisian" lang="fy" hreflang="fy" data-title="Genetyske technology" data-language-autonym="Frysk" data-language-local-name="Western Frisian" class="interlanguage-link-target">Frysk</a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Innealt%C3%B3ireacht_gh%C3%A9initeach" title="Innealtóireacht ghéiniteach – Irish" lang="ga" hreflang="ga" data-title="Innealtóireacht ghéiniteach" data-language-autonym="Gaeilge" data-language-local-name="Irish" class="interlanguage-link-target">Gaeilge</a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Enxe%C3%B1ar%C3%ADa_xen%C3%A9tica" title="Enxeñaría xenética – Galician" lang="gl" hreflang="gl" data-title="Enxeñaría xenética" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target">Galego</a></li><li class="interlanguage-link interwiki-gan mw-list-item"><a href="https://gan.wikipedia.org/wiki/%E5%9F%BA%E5%9B%A0%E5%B7%A5%E7%A8%8B" title="基因工程 – Gan" lang="gan" hreflang="gan" data-title="基因工程" data-language-autonym="贛語" data-language-local-name="Gan" class="interlanguage-link-target">贛語</a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%9C%A0%EC%A0%84%EA%B3%B5%ED%95%99" title="유전공학 – Korean" lang="ko" hreflang="ko" data-title="유전공학" data-language-autonym="한국어" data-language-local-name="Korean" class="interlanguage-link-target">한국어</a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%B3%D5%A5%D5%B6%D5%A5%D5%BF%D5%AB%D5%AF%D5%A1%D5%AF%D5%A1%D5%B6_%D5%B3%D5%A1%D6%80%D5%BF%D5%A1%D6%80%D5%A1%D5%A3%D5%AB%D5%BF%D5%B8%D6%82%D5%A9%D5%B5%D5%B8%D6%82%D5%B6" title="Գենետիկական ճարտարագիտություն – Armenian" lang="hy" hreflang="hy" data-title="Գենետիկական ճարտարագիտություն" data-language-autonym="Հայերեն" data-language-local-name="Armenian" class="interlanguage-link-target">Հայերեն</a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%85%E0%A4%A8%E0%A5%81%E0%A4%B5%E0%A4%82%E0%A4%B6%E0%A4%BF%E0%A4%95_%E0%A4%85%E0%A4%AD%E0%A4%BF%E0%A4%AF%E0%A4%BE%E0%A4%82%E0%A4%A4%E0%A5%8D%E0%A4%B0%E0%A4%BF%E0%A4%95%E0%A5%80" title="अनुवंशिक अभियांत्रिकी – Hindi" lang="hi" hreflang="hi" data-title="अनुवंशिक अभियांत्रिकी" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target">हिन्दी</a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Gensko_in%C5%BEenjerstvo" title="Gensko inženjerstvo – Croatian" lang="hr" hreflang="hr" data-title="Gensko inženjerstvo" data-language-autonym="Hrvatski" data-language-local-name="Croatian" class="interlanguage-link-target">Hrvatski</a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Rekayasa_genetik" title="Rekayasa genetik – Indonesian" lang="id" hreflang="id" data-title="Rekayasa genetik" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target">Bahasa Indonesia</a></li><li class="interlanguage-link interwiki-zu mw-list-item"><a href="https://zu.wikipedia.org/wiki/UmNgcikisho_wezifuzisi" title="UmNgcikisho wezifuzisi – Zulu" lang="zu" hreflang="zu" data-title="UmNgcikisho wezifuzisi" data-language-autonym="IsiZulu" data-language-local-name="Zulu" class="interlanguage-link-target">IsiZulu</a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Ingegneria_genetica" title="Ingegneria genetica – Italian" lang="it" hreflang="it" data-title="Ingegneria genetica" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target">Italiano</a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%94%D7%A0%D7%93%D7%A1%D7%94_%D7%92%D7%A0%D7%98%D7%99%D7%AA" title="הנדסה גנטית – Hebrew" lang="he" hreflang="he" data-title="הנדסה גנטית" data-language-autonym="עברית" data-language-local-name="Hebrew" class="interlanguage-link-target">עברית</a></li><li class="interlanguage-link interwiki-kn mw-list-item"><a href="https://kn.wikipedia.org/wiki/%E0%B2%A4%E0%B2%B3%E0%B3%80%E0%B2%AF_%E0%B2%8E%E0%B2%82%E0%B2%9C%E0%B2%BF%E0%B2%A8%E0%B2%BF%E0%B2%AF%E0%B2%B0%E0%B2%BF%E0%B2%82%E0%B2%97%E0%B3%8D" title="ತಳೀಯ ಎಂಜಿನಿಯರಿಂಗ್ – Kannada" lang="kn" hreflang="kn" data-title="ತಳೀಯ ಎಂಜಿನಿಯರಿಂಗ್" data-language-autonym="ಕನ್ನಡ" data-language-local-name="Kannada" class="interlanguage-link-target">ಕನ್ನಡ</a></li><li class="interlanguage-link interwiki-ka mw-list-item"><a href="https://ka.wikipedia.org/wiki/%E1%83%92%E1%83%94%E1%83%9C%E1%83%A3%E1%83%A0%E1%83%98_%E1%83%98%E1%83%9C%E1%83%9F%E1%83%98%E1%83%9C%E1%83%94%E1%83%A0%E1%83%98%E1%83%90" title="გენური ინჟინერია – Georgian" lang="ka" hreflang="ka" data-title="გენური ინჟინერია" data-language-autonym="ქართული" data-language-local-name="Georgian" class="interlanguage-link-target">ქართული</a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B4%D1%96%D0%BA_%D0%B8%D0%BD%D0%B6%D0%B5%D0%BD%D0%B5%D1%80%D0%B8%D1%8F" title="Гендік инженерия – Kazakh" lang="kk" hreflang="kk" data-title="Гендік инженерия" data-language-autonym="Қазақша" data-language-local-name="Kazakh" class="interlanguage-link-target">Қазақша</a></li><li class="interlanguage-link interwiki-ht mw-list-item"><a href="https://ht.wikipedia.org/wiki/Rekonbinezon_jenetik" title="Rekonbinezon jenetik – Haitian Creole" lang="ht" hreflang="ht" data-title="Rekonbinezon jenetik" data-language-autonym="Kreyòl ayisyen" data-language-local-name="Haitian Creole" class="interlanguage-link-target">Kreyòl ayisyen</a></li><li class="interlanguage-link interwiki-gcr mw-list-item"><a href="https://gcr.wikipedia.org/wiki/J%C3%A9ni_j%C3%A9n%C3%A9tik" title="Jéni jénétik – Guianan Creole" lang="gcr" hreflang="gcr" data-title="Jéni jénétik" data-language-autonym="Kriyòl gwiyannen" data-language-local-name="Guianan Creole" class="interlanguage-link-target">Kriyòl gwiyannen</a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/Endazyariya_b%C3%BBmay%C3%AEk" title="Endazyariya bûmayîk – Kurdish" lang="ku" hreflang="ku" data-title="Endazyariya bûmayîk" data-language-autonym="Kurdî" data-language-local-name="Kurdish" class="interlanguage-link-target">Kurdî</a></li><li class="interlanguage-link interwiki-ky mw-list-item"><a href="https://ky.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0_%D0%B8%D0%BD%D0%B6%D0%B5%D0%BD%D0%B5%D1%80%D0%B8%D1%8F%D1%81%D1%8B" title="Генетика инженериясы – Kyrgyz" lang="ky" hreflang="ky" data-title="Генетика инженериясы" data-language-autonym="Кыргызча" data-language-local-name="Kyrgyz" class="interlanguage-link-target">Кыргызча</a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Technologia_genetica" title="Technologia genetica – Latin" lang="la" hreflang="la" data-title="Technologia genetica" data-language-autonym="Latina" data-language-local-name="Latin" class="interlanguage-link-target">Latina</a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/G%C4%93nu_in%C5%BEenierija" title="Gēnu inženierija – Latvian" lang="lv" hreflang="lv" data-title="Gēnu inženierija" data-language-autonym="Latviešu" data-language-local-name="Latvian" class="interlanguage-link-target">Latviešu</a></li><li class="interlanguage-link interwiki-lb mw-list-item"><a href="https://lb.wikipedia.org/wiki/Geentechnik" title="Geentechnik – Luxembourgish" lang="lb" hreflang="lb" data-title="Geentechnik" data-language-autonym="Lëtzebuergesch" data-language-local-name="Luxembourgish" class="interlanguage-link-target">Lëtzebuergesch</a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Gen%C5%B3_in%C5%BEinerija" title="Genų inžinerija – Lithuanian" lang="lt" hreflang="lt" data-title="Genų inžinerija" data-language-autonym="Lietuvių" data-language-local-name="Lithuanian" class="interlanguage-link-target">Lietuvių</a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/G%C3%A9nseb%C3%A9szet" title="Génsebészet – Hungarian" lang="hu" hreflang="hu" data-title="Génsebészet" data-language-autonym="Magyar" data-language-local-name="Hungarian" class="interlanguage-link-target">Magyar</a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D1%81%D0%BA%D0%BE_%D0%B8%D0%BD%D0%B6%D0%B5%D0%BD%D0%B5%D1%80%D1%81%D1%82%D0%B2%D0%BE" title="Генетско инженерство – Macedonian" lang="mk" hreflang="mk" data-title="Генетско инженерство" data-language-autonym="Македонски" data-language-local-name="Macedonian" class="interlanguage-link-target">Македонски</a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%9C%E0%B4%A8%E0%B4%BF%E0%B4%A4%E0%B4%95_%E0%B4%8E%E0%B5%BB%E0%B4%9C%E0%B4%BF%E0%B4%A8%E0%B5%80%E0%B4%AF%E0%B4%B1%E0%B4%BF%E0%B4%99%E0%B5%8D%E0%B4%99%E0%B5%8D" title="ജനിതക എൻജിനീയറിങ്ങ് – Malayalam" lang="ml" hreflang="ml" data-title="ജനിതക എൻജിനീയറിങ്ങ്" data-language-autonym="മലയാളം" data-language-local-name="Malayalam" class="interlanguage-link-target">മലയാളം</a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Kejuruteraan_genetik" title="Kejuruteraan genetik – Malay" lang="ms" hreflang="ms" data-title="Kejuruteraan genetik" data-language-autonym="Bahasa Melayu" data-language-local-name="Malay" class="interlanguage-link-target">Bahasa Melayu</a></li><li class="interlanguage-link interwiki-mwl mw-list-item"><a href="https://mwl.wikipedia.org/wiki/Angenharie_gen%C3%A9tica" title="Angenharie genética – Mirandese" lang="mwl" hreflang="mwl" data-title="Angenharie genética" data-language-autonym="Mirandés" data-language-local-name="Mirandese" class="interlanguage-link-target">Mirandés</a></li><li class="interlanguage-link interwiki-mn mw-list-item"><a href="https://mn.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B8%D0%B9%D0%BD_%D0%B8%D0%BD%D0%B6%D0%B5%D0%BD%D0%B5%D1%80%D1%87%D0%BB%D1%8D%D0%BB" title="Генийн инженерчлэл – Mongolian" lang="mn" hreflang="mn" data-title="Генийн инженерчлэл" data-language-autonym="Монгол" data-language-local-name="Mongolian" class="interlanguage-link-target">Монгол</a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Genetische_technologie" title="Genetische technologie – Dutch" lang="nl" hreflang="nl" data-title="Genetische technologie" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target">Nederlands</a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E9%81%BA%E4%BC%9D%E5%AD%90%E5%B7%A5%E5%AD%A6" title="遺伝子工学 – Japanese" lang="ja" hreflang="ja" data-title="遺伝子工学" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target">日本語</a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Gensl%C3%B8yd" title="Gensløyd – Norwegian Bokmål" lang="nb" hreflang="nb" data-title="Gensløyd" data-language-autonym="Norsk bokmål" data-language-local-name="Norwegian Bokmål" class="interlanguage-link-target">Norsk bokmål</a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Gensl%C3%B8yd" title="Gensløyd – Norwegian Nynorsk" lang="nn" hreflang="nn" data-title="Gensløyd" data-language-autonym="Norsk nynorsk" data-language-local-name="Norwegian Nynorsk" class="interlanguage-link-target">Norsk nynorsk</a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Genetik_injeneriya" title="Genetik injeneriya – Uzbek" lang="uz" hreflang="uz" data-title="Genetik injeneriya" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="Uzbek" class="interlanguage-link-target">Oʻzbekcha / ўзбекча</a></li><li class="interlanguage-link interwiki-pa mw-list-item"><a href="https://pa.wikipedia.org/wiki/%E0%A8%9C%E0%A8%A3%E0%A8%A8_%E0%A8%87%E0%A9%B0%E0%A8%9C%E0%A9%80%E0%A8%A8%E0%A9%80%E0%A8%85%E0%A8%B0%E0%A9%80" title="ਜਣਨ ਇੰਜੀਨੀਅਰੀ – Punjabi" lang="pa" hreflang="pa" data-title="ਜਣਨ ਇੰਜੀਨੀਅਰੀ" data-language-autonym="ਪੰਜਾਬੀ" data-language-local-name="Punjabi" class="interlanguage-link-target">ਪੰਜਾਬੀ</a></li><li class="interlanguage-link interwiki-ps mw-list-item"><a href="https://ps.wikipedia.org/wiki/%D8%AF_%D8%AC%D9%86%D8%AA%DB%8C%DA%A9_%D8%A7%D9%86%D8%AC%D9%86%DB%8C%D8%B1%D9%8A" title="د جنتیک انجنیري – Pashto" lang="ps" hreflang="ps" data-title="د جنتیک انجنیري" data-language-autonym="پښتو" data-language-local-name="Pashto" class="interlanguage-link-target">پښتو</a></li><li class="interlanguage-link interwiki-jam mw-list-item"><a href="https://jam.wikipedia.org/wiki/Jinetik_injinierin" title="Jinetik injinierin – Jamaican Creole English" lang="jam" hreflang="jam" data-title="Jinetik injinierin" data-language-autonym="Patois" data-language-local-name="Jamaican Creole English" class="interlanguage-link-target">Patois</a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/In%C5%BCynieria_genetyczna" title="Inżynieria genetyczna – Polish" lang="pl" hreflang="pl" data-title="Inżynieria genetyczna" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target">Polski</a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Engenharia_gen%C3%A9tica" title="Engenharia genética – Portuguese" lang="pt" hreflang="pt" data-title="Engenharia genética" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target">Português</a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Inginerie_genetic%C4%83" title="Inginerie genetică – Romanian" lang="ro" hreflang="ro" data-title="Inginerie genetică" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target">Română</a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%B8%D0%BD%D0%B6%D0%B5%D0%BD%D0%B5%D1%80%D0%B8%D1%8F" title="Генетическая инженерия – Russian" lang="ru" hreflang="ru" data-title="Генетическая инженерия" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target">Русский</a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Inxhinieria_gjenetike" title="Inxhinieria gjenetike – Albanian" lang="sq" hreflang="sq" data-title="Inxhinieria gjenetike" data-language-autonym="Shqip" data-language-local-name="Albanian" class="interlanguage-link-target">Shqip</a></li><li class="interlanguage-link interwiki-scn mw-list-item"><a href="https://scn.wikipedia.org/wiki/Ncignir%C3%ACa_gin%C3%A8tica" title="Ncignirìa ginètica – Sicilian" lang="scn" hreflang="scn" data-title="Ncignirìa ginètica" data-language-autonym="Sicilianu" data-language-local-name="Sicilian" class="interlanguage-link-target">Sicilianu</a></li><li class="interlanguage-link interwiki-si mw-list-item"><a href="https://si.wikipedia.org/wiki/%E0%B6%A2%E0%B7%8F%E0%B6%B1_%E0%B6%89%E0%B6%82%E0%B6%A2%E0%B7%92%E0%B6%B1%E0%B7%9A%E0%B6%BB%E0%B7%94_%E0%B7%80%E0%B7%92%E0%B6%AF%E0%B7%8A%E2%80%8D%E0%B6%BA%E0%B7%8F%E0%B7%80" title="ජාන ඉංජිනේරු විද්‍යාව – Sinhala" lang="si" hreflang="si" data-title="ජාන ඉංජිනේරු විද්‍යාව" data-language-autonym="සිංහල" data-language-local-name="Sinhala" class="interlanguage-link-target">සිංහල</a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Genetic_engineering" title="Genetic engineering – Simple English" lang="en-simple" hreflang="en-simple" data-title="Genetic engineering" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target">Simple English</a></li><li class="interlanguage-link interwiki-sd mw-list-item"><a href="https://sd.wikipedia.org/wiki/%D8%AA%D8%B9%D8%AC%D9%8A%D9%84_%D9%88%D8%B1%D8%A7%D8%AB%D8%AA" title="تعجيل وراثت – Sindhi" lang="sd" hreflang="sd" data-title="تعجيل وراثت" data-language-autonym="سنڌي" data-language-local-name="Sindhi" class="interlanguage-link-target">سنڌي</a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Genetsko_in%C5%BEenirstvo" title="Genetsko inženirstvo – Slovenian" lang="sl" hreflang="sl" data-title="Genetsko inženirstvo" data-language-autonym="Slovenščina" data-language-local-name="Slovenian" class="interlanguage-link-target">Slovenščina</a></li><li class="interlanguage-link interwiki-ckb mw-list-item"><a href="https://ckb.wikipedia.org/wiki/%D8%A6%DB%95%D9%86%D8%AF%D8%A7%D8%B2%DB%95%DB%8C_%D8%A8%DB%86%D9%85%D8%A7%D9%88%DB%95%DB%8C%DB%8C" title="ئەندازەی بۆماوەیی – Central Kurdish" lang="ckb" hreflang="ckb" data-title="ئەندازەی بۆماوەیی" data-language-autonym="کوردی" data-language-local-name="Central Kurdish" class="interlanguage-link-target">کوردی</a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%93%D0%B5%D0%BD%D0%B5%D1%82%D0%B8%D1%87%D0%BA%D0%B8_%D0%B8%D0%BD%D0%B6%D0%B5%D1%9A%D0%B5%D1%80%D0%B8%D0%BD%D0%B3" title="Генетички инжењеринг – Serbian" lang="sr" hreflang="sr" data-title="Генетички инжењеринг" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target">Српски / srpski</a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Geneti%C4%8Dki_in%C5%BEenjering" title="Genetički inženjering – Serbo-Croatian" lang="sh" hreflang="sh" data-title="Genetički inženjering" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Serbo-Croatian" class="interlanguage-link-target">Srpskohrvatski / српскохрватски</a></li><li class="interlanguage-link interwiki-su mw-list-item"><a href="https://su.wikipedia.org/wiki/R%C3%A9kayasa_g%C3%A9n%C3%A9tik" title="Rékayasa génétik – Sundanese" lang="su" hreflang="su" data-title="Rékayasa génétik" data-language-autonym="Sunda" data-language-local-name="Sundanese" class="interlanguage-link-target">Sunda</a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Geenitekniikka" title="Geenitekniikka – Finnish" lang="fi" hreflang="fi" data-title="Geenitekniikka" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target">Suomi</a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Genteknik" title="Genteknik – Swedish" lang="sv" hreflang="sv" data-title="Genteknik" data-language-autonym="Svenska" data-language-local-name="Swedish" class="interlanguage-link-target">Svenska</a></li><li class="interlanguage-link interwiki-tl mw-list-item"><a href="https://tl.wikipedia.org/wiki/Inhenyeriyang_henetiko" title="Inhenyeriyang henetiko – Tagalog" lang="tl" hreflang="tl" data-title="Inhenyeriyang henetiko" data-language-autonym="Tagalog" data-language-local-name="Tagalog" class="interlanguage-link-target">Tagalog</a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%AE%E0%AE%B0%E0%AE%AA%E0%AE%A3%E0%AF%81%E0%AE%AA%E0%AF%8D_%E0%AE%AA%E0%AF%8A%E0%AE%B1%E0%AE%BF%E0%AE%AF%E0%AE%BF%E0%AE%AF%E0%AE%B2%E0%AF%8D" title="மரபணுப் பொறியியல் – Tamil" lang="ta" hreflang="ta" data-title="மரபணுப் பொறியியல்" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target">தமிழ்</a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%9E%E0%B8%B1%E0%B8%99%E0%B8%98%E0%B8%B8%E0%B8%A7%E0%B8%B4%E0%B8%A8%E0%B8%A7%E0%B8%81%E0%B8%A3%E0%B8%A3%E0%B8%A1" title="พันธุวิศวกรรม – Thai" lang="th" hreflang="th" data-title="พันธุวิศวกรรม" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target">ไทย</a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Genetik_m%C3%BChendisli%C4%9Fi" title="Genetik mühendisliği – Turkish" lang="tr" hreflang="tr" data-title="Genetik mühendisliği" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target">Türkçe</a></li><li class="interlanguage-link interwiki-tk mw-list-item"><a href="https://tk.wikipedia.org/wiki/Genetika_in%C5%BEenerligi" title="Genetika inženerligi – Turkmen" lang="tk" hreflang="tk" data-title="Genetika inženerligi" data-language-autonym="Türkmençe" data-language-local-name="Turkmen" class="interlanguage-link-target">Türkmençe</a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a 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.sidebar-content{padding:0 0.5em 0.4em}.mw-parser-output .sidebar-content-with-subgroup{padding:0.1em 0.4em 0.2em}.mw-parser-output .sidebar-above,.mw-parser-output .sidebar-below{padding:0.3em 0.8em;font-weight:bold}.mw-parser-output .sidebar-collapse .sidebar-above,.mw-parser-output .sidebar-collapse .sidebar-below{border-top:1px solid #aaa;border-bottom:1px solid #aaa}.mw-parser-output .sidebar-navbar{text-align:right;font-size:115%;padding:0 0.4em 0.4em}.mw-parser-output .sidebar-list-title{padding:0 0.4em;text-align:left;font-weight:bold;line-height:1.6em;font-size:105%}.mw-parser-output .sidebar-list-title-c{padding:0 0.4em;text-align:center;margin:0 3.3em}@media(max-width:640px){body.mediawiki .mw-parser-output .sidebar{width:100%!important;clear:both;float:none!important;margin-left:0!important;margin-right:0!important}}body.skin--responsive .mw-parser-output .sidebar a>img{max-width:none!important}@media screen{html.skin-theme-clientpref-night .mw-parser-output .sidebar:not(.notheme) .sidebar-list-title,html.skin-theme-clientpref-night .mw-parser-output .sidebar:not(.notheme) .sidebar-title-with-pretitle{background:transparent!important}html.skin-theme-clientpref-night .mw-parser-output .sidebar:not(.notheme) .sidebar-title-with-pretitle a{color:var(--color-progressive)!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .sidebar:not(.notheme) .sidebar-list-title,html.skin-theme-clientpref-os .mw-parser-output .sidebar:not(.notheme) .sidebar-title-with-pretitle{background:transparent!important}html.skin-theme-clientpref-os .mw-parser-output .sidebar:not(.notheme) .sidebar-title-with-pretitle a{color:var(--color-progressive)!important}}@media print{body.ns-0 .mw-parser-output .sidebar{display:none!important}}</style><table class="sidebar nomobile nowraplinks hlist"><tbody><tr><td class="sidebar-pretitle" style="padding-bottom:0.15em;">Part of <a href="/wiki/Category:Genetic_engineering" title="Category:Genetic engineering">a series</a> on</td></tr><tr><th class="sidebar-title-with-pretitle" style="font-size:175%;padding-top:0.2em;font-weight:normal;"><a class="mw-selflink selflink">Genetic engineering</a></th></tr><tr><td class="sidebar-image"><a href="/wiki/File:Genetic_engineering_logo.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a1/Genetic_engineering_logo.png/150px-Genetic_engineering_logo.png" decoding="async" width="150" height="141" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a1/Genetic_engineering_logo.png/225px-Genetic_engineering_logo.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a1/Genetic_engineering_logo.png/300px-Genetic_engineering_logo.png 2x" data-file-width="459" data-file-height="432" /></a></td></tr><tr><td class="sidebar-content" style="padding:0.2em 0.4em 0.4em;;background:none;font-size:40%;line-height:0.4em;">  </td> </tr><tr><th class="sidebar-heading"> <a href="/wiki/Genetically_modified_organism" title="Genetically modified organism">Genetically modified organisms</a></th></tr><tr><td class="sidebar-content" style="padding:0.2em 0.4em 0.4em;"> <ul><li><a href="/wiki/Genetically_modified_bacteria" title="Genetically modified bacteria">Bacteria</a></li> <li><a href="/wiki/Genetically_modified_virus" title="Genetically modified virus">Viruses</a></li></ul> <ul><li><a href="/wiki/Genetically_modified_animal" title="Genetically modified animal">Animals</a> <ul><li><a href="/wiki/Genetically_modified_mammal" title="Genetically modified mammal">Mammals</a></li> <li><a href="/wiki/Genetically_modified_fish" title="Genetically modified fish">Fish</a></li> <li><a href="/wiki/Genetically_modified_insect" title="Genetically modified insect">Insects</a></li></ul></li></ul> <ul><li><a href="/wiki/Genetically_modified_plant" title="Genetically modified plant">Plants</a> <ul><li><a href="/wiki/Genetically_modified_maize" title="Genetically modified maize">Maize/corn</a></li> <li><a href="/wiki/Genetically_modified_rice" title="Genetically modified rice">Rice</a></li> <li><a href="/wiki/Genetically_modified_soybean" title="Genetically modified soybean">Soybean</a></li> <li><a href="/wiki/Genetically_modified_potato" title="Genetically modified potato">Potato</a></li></ul></li></ul></td> </tr><tr><th class="sidebar-heading"> History and regulation</th></tr><tr><td class="sidebar-content" style="padding:0.2em 0.4em 0.4em;"> <ul><li><a href="/wiki/History_of_genetic_engineering" title="History of genetic engineering">History</a></li></ul> <ul><li><a href="/wiki/Regulation_of_genetic_engineering" title="Regulation of genetic engineering">Regulation</a> <ul><li><a href="/wiki/Substantial_equivalence" title="Substantial equivalence">Substantial equivalence</a></li> <li><a href="/wiki/Cartagena_Protocol_on_Biosafety" title="Cartagena Protocol on Biosafety">Cartagena Protocol on Biosafety</a></li></ul></li></ul></td> </tr><tr><th class="sidebar-heading"> Process</th></tr><tr><td class="sidebar-content" style="padding:0.2em 0.4em 0.4em;"> <ul><li><a href="/wiki/Genetic_engineering_techniques" title="Genetic engineering techniques">Techniques</a></li> <li><a href="/wiki/Molecular_cloning" title="Molecular cloning">Molecular cloning</a> <ul><li><a href="/wiki/Recombinant_DNA" title="Recombinant DNA">Recombinant DNA</a></li></ul></li> <li><a href="/wiki/Gene_delivery" title="Gene delivery">Gene delivery</a> <ul><li><a href="/wiki/Transformation_(genetics)" class="mw-redirect" title="Transformation (genetics)">Transformation</a></li> <li><a href="/wiki/Transfection" title="Transfection">Transfection</a></li> <li><a href="/wiki/Transduction_(genetics)" title="Transduction (genetics)">Transduction</a></li></ul></li> <li><a href="/wiki/Genome_editing" title="Genome editing">Genome editing</a> <ul><li><a href="/wiki/TALEN" class="mw-redirect" title="TALEN">TALEN</a></li> <li><a href="/wiki/CRISPR" title="CRISPR">CRISPR</a></li></ul></li></ul></td> </tr><tr><th class="sidebar-heading"> Applications</th></tr><tr><td class="sidebar-content" style="padding:0.2em 0.4em 0.4em;"> <ul><li><a href="/wiki/Genetically_modified_crops" title="Genetically modified crops">Genetically modified crops</a> <ul><li><a href="/wiki/Genetically_modified_food" title="Genetically modified food">food</a></li></ul></li> <li><a href="/wiki/Gene_therapy" title="Gene therapy">Gene therapy</a></li> <li><a href="/wiki/Designer_baby" title="Designer baby">Designer baby</a></li></ul></td> </tr><tr><th class="sidebar-heading"> Controversies</th></tr><tr><td class="sidebar-content" style="padding:0.2em 0.4em 0.4em;"> <ul><li><a href="/wiki/Genetically_modified_food_controversies" title="Genetically modified food controversies">Genetically modified food controversies</a></li> <li><a href="/wiki/GMO_conspiracy_theories" title="GMO conspiracy theories">GMO conspiracy theories</a></li> <li><a href="/wiki/Pusztai_affair" title="Pusztai affair">Pusztai affair</a></li> <li><a href="/wiki/S%C3%A9ralini_affair" title="Séralini affair">Séralini affair</a></li> <li><a href="/wiki/StarLink_corn_recall" title="StarLink corn recall">StarLink corn recall</a></li> <li><a href="/wiki/He_Jiankui_affair" title="He Jiankui affair">He Jiankui affair</a></li></ul></td> </tr><tr><td class="sidebar-navbar"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Genetic_engineering_sidebar" title="Template:Genetic engineering sidebar"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Genetic_engineering_sidebar" title="Template talk:Genetic engineering sidebar"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Genetic_engineering_sidebar" title="Special:EditPage/Template:Genetic engineering sidebar"><abbr title="Edit this template">e</abbr></a></li></ul></div></td></tr></tbody></table> Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's <a href="/wiki/Gene" title="Gene">genes</a> using <a href="/wiki/Technology" title="Technology">technology</a>. It is a set of <a href="/wiki/Genetic_engineering_techniques" title="Genetic engineering techniques">technologies</a> used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel <a href="/wiki/Organisms" class="mw-redirect" title="Organisms">organisms</a>. New <a href="/wiki/DNA" title="DNA">DNA</a> is obtained by either isolating and copying the genetic material of interest using <a href="/wiki/Recombinant_DNA" title="Recombinant DNA">recombinant DNA</a> methods or by <a href="/wiki/Artificial_gene_synthesis" title="Artificial gene synthesis">artificially synthesising</a> the DNA. A <a href="/wiki/Vector_(molecular_biology)" title="Vector (molecular biology)">construct</a> is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by <a href="/wiki/Paul_Berg" title="Paul Berg">Paul Berg</a> in 1972 by combining DNA from the monkey virus <a href="/wiki/SV40" title="SV40">SV40</a> with the <a href="/wiki/Lambda_phage" title="Lambda phage">lambda virus</a>. As well as inserting <a href="/wiki/Gene" title="Gene">genes</a>, the process can be used to remove, or "<a href="/wiki/Gene_knockout" title="Gene knockout">knock out</a>", genes. The new DNA can be inserted randomly, or <a href="/wiki/Gene_targeting" title="Gene targeting">targeted</a> to a specific part of the <a href="/wiki/Genome" title="Genome">genome</a>.<a href="#cite_note-1">[1]</a> An organism that is generated through genetic engineering is considered to be genetically modified (GM) and the resulting entity is a <a href="/wiki/Genetically_modified_organism" title="Genetically modified organism">genetically modified organism</a> (GMO). The first GMO was a <a href="/wiki/Genetically_modified_bacterium" class="mw-redirect" title="Genetically modified bacterium">bacterium</a> generated by <a href="/wiki/Herbert_Boyer" title="Herbert Boyer">Herbert Boyer</a> and <a href="/wiki/Stanley_Norman_Cohen" title="Stanley Norman Cohen">Stanley Cohen</a> in 1973. <a href="/wiki/Rudolf_Jaenisch" title="Rudolf Jaenisch">Rudolf Jaenisch</a> created the first GM animal when he inserted foreign DNA into a <a href="/wiki/Genetically_modified_mouse" title="Genetically modified mouse">mouse</a> in 1974. The first company to focus on genetic engineering, <a href="/wiki/Genentech" title="Genentech">Genentech</a>, was founded in 1976 and started the production of human proteins. Genetically engineered human <a href="/wiki/Insulin" title="Insulin">insulin</a> was produced in 1978 and insulin-producing bacteria were commercialised in 1982. <a href="/wiki/Genetically_modified_food" title="Genetically modified food">Genetically modified food</a> has been sold since 1994, with the release of the <a href="/wiki/Flavr_Savr" title="Flavr Savr">Flavr Savr</a> tomato. The Flavr Savr was engineered to have a longer shelf life, but most current GM crops are modified to increase resistance to insects and herbicides. <a href="/wiki/GloFish" title="GloFish">GloFish</a>, the first GMO designed as a pet, was sold in the <a href="/wiki/United_States" title="United States">United States</a> in December 2003. In 2016 <a href="/wiki/AquAdvantage_salmon" title="AquAdvantage salmon">salmon</a> modified with a growth hormone were sold. Genetic engineering has been applied in numerous fields including research, medicine, industrial biotechnology and agriculture. In research, GMOs are used to study gene function and expression through loss of function, gain of function, tracking and expression experiments. By knocking out genes responsible for certain conditions it is possible to create <a href="/wiki/Model_organism" title="Model organism">animal model organisms</a> of human diseases. As well as producing hormones, vaccines and other drugs, genetic engineering has the potential to cure genetic diseases through <a href="/wiki/Gene_therapy" title="Gene therapy">gene therapy</a>. <a href="/wiki/Chinese_hamster_ovary_cell" title="Chinese hamster ovary cell">Chinese hamster ovary (CHO) cells</a> are used in industrial genetic engineering. Additionally <a href="/wiki/MRNA_vaccine" title="MRNA vaccine">mRNA vaccines</a> are made through genetic engineering to treat viruses such as <a href="/wiki/COVID-19_vaccine" title="COVID-19 vaccine">COVID-19</a>. The same techniques that are used to produce drugs can also have industrial applications such as producing enzymes for laundry detergent, cheeses and other products. The rise of commercialised <a href="/wiki/Genetically_modified_crops" title="Genetically modified crops">genetically modified crops</a> has provided economic benefit to farmers in many different countries, but has also been the source of most of the <a href="/wiki/Genetically_modified_food_controversies" title="Genetically modified food controversies">controversy</a> surrounding the technology. This has been present since its early use; the first field trials were destroyed by anti-GM activists. Although there is a <a href="/wiki/Scientific_consensus" title="Scientific consensus">scientific consensus</a> that currently available food derived from GM crops poses no greater risk to human health than conventional food, critics consider GM food safety a leading concern. <a href="/wiki/Gene_flow" title="Gene flow">Gene flow</a>, impact on non-target organisms, control of the food supply and <a href="/wiki/Intellectual_property" title="Intellectual property">intellectual property</a> rights have also been raised as potential issues. These concerns have led to the development of a regulatory framework, which started in 1975. It has led to an international treaty, the <a href="/wiki/Cartagena_Protocol_on_Biosafety" title="Cartagena Protocol on Biosafety">Cartagena Protocol on Biosafety</a>, that was adopted in 2000. Individual countries have developed their own regulatory systems regarding GMOs, with the most marked differences occurring between the United States and <a href="/wiki/Europe" title="Europe">Europe</a>. <style data-mw-deduplicate="TemplateStyles:r1224211176">.mw-parser-output .quotebox{background-color:#F9F9F9;border:1px solid #aaa;box-sizing:border-box;padding:10px;font-size:88%;max-width:100%}.mw-parser-output .quotebox.floatleft{margin:.5em 1.4em .8em 0}.mw-parser-output .quotebox.floatright{margin:.5em 0 .8em 1.4em}.mw-parser-output .quotebox.centered{overflow:hidden;position:relative;margin:.5em auto .8em auto}.mw-parser-output .quotebox.floatleft span,.mw-parser-output .quotebox.floatright span{font-style:inherit}.mw-parser-output .quotebox>blockquote{margin:0;padding:0;border-left:0;font-family:inherit;font-size:inherit}.mw-parser-output .quotebox-title{text-align:center;font-size:110%;font-weight:bold}.mw-parser-output .quotebox-quote>:first-child{margin-top:0}.mw-parser-output .quotebox-quote:last-child>:last-child{margin-bottom:0}.mw-parser-output .quotebox-quote.quoted:before{font-family:"Times New Roman",serif;font-weight:bold;font-size:large;color:gray;content:" “ ";vertical-align:-45%;line-height:0}.mw-parser-output .quotebox-quote.quoted:after{font-family:"Times New Roman",serif;font-weight:bold;font-size:large;color:gray;content:" ” ";line-height:0}.mw-parser-output .quotebox .left-aligned{text-align:left}.mw-parser-output .quotebox .right-aligned{text-align:right}.mw-parser-output .quotebox .center-aligned{text-align:center}.mw-parser-output .quotebox .quote-title,.mw-parser-output .quotebox .quotebox-quote{display:block}.mw-parser-output .quotebox cite{display:block;font-style:normal}@media screen and (max-width:640px){.mw-parser-output .quotebox{width:100%!important;margin:0 0 .8em!important;float:none!important}}</style><div class="quotebox pullquote floatright" style="width:30%; ;"> <div class="quotebox-title" style=""><a href="/wiki/International_Union_of_Pure_and_Applied_Chemistry" title="International Union of Pure and Applied Chemistry">IUPAC</a> definition</div> <blockquote class="quotebox-quote left-aligned" style=""> Genetic engineering: Process of inserting new genetic information into existing cells in order to modify a specific organism for the purpose of changing its characteristics. Note: Adapted from ref.<a href="#cite_note-2">[2]</a><a href="#cite_note-3">[3]</a> </blockquote> </div> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Overview">Overview</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=1" title="Edit section: Overview">edit</a>]</div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Breeding_transgenesis_cisgenesis.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/80/Breeding_transgenesis_cisgenesis.svg/370px-Breeding_transgenesis_cisgenesis.svg.png" decoding="async" width="370" height="316" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/80/Breeding_transgenesis_cisgenesis.svg/555px-Breeding_transgenesis_cisgenesis.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/80/Breeding_transgenesis_cisgenesis.svg/740px-Breeding_transgenesis_cisgenesis.svg.png 2x" data-file-width="1077" data-file-height="921" /></a><figcaption>Comparison of conventional plant breeding with <a href="/wiki/Transgenic" class="mw-redirect" title="Transgenic">transgenic</a> and <a href="/wiki/Cisgenic" class="mw-redirect" title="Cisgenic">cisgenic</a> genetic modification</figcaption></figure> Genetic engineering is a process that alters the genetic structure of an organism by either removing or introducing <a href="/wiki/DNA" title="DNA">DNA</a>, or modifying existing genetic material in situ. Unlike traditional <a href="/wiki/Animal_breeding" title="Animal breeding">animal</a> and <a href="/wiki/Plant_breeding" title="Plant breeding">plant breeding</a>, which involves doing multiple crosses and then selecting for the organism with the desired <a href="/wiki/Phenotype" title="Phenotype">phenotype</a>, genetic engineering takes the <a href="/wiki/Gene" title="Gene">gene</a> directly from one organism and delivers it to the other. This is much faster, can be used to insert any genes from any organism (even ones from different <a href="/wiki/Domain_(biology)" title="Domain (biology)">domains</a>) and prevents other undesirable genes from also being added.<a href="#cite_note-4">[4]</a> Genetic engineering could potentially fix severe <a href="/wiki/Genetic_disorder" title="Genetic disorder">genetic disorders</a> in humans by replacing the defective gene with a functioning one.<a href="#cite_note-5">[5]</a> It is an important tool in research that allows the function of specific genes to be studied.<a href="#cite_note-6">[6]</a> Drugs, vaccines and other products have been harvested from organisms engineered to produce them.<a href="#cite_note-7">[7]</a> <a href="/wiki/List_of_genetically_modified_crops" title="List of genetically modified crops">Crops</a> have been developed that aid <a href="/wiki/Food_security" title="Food security">food security</a> by increasing yield, nutritional value and tolerance to environmental stresses.<a href="#cite_note-8">[8]</a> The DNA can be introduced directly into the <a href="/wiki/Host_organism" class="mw-redirect" title="Host organism">host organism</a> or into a cell that is then <a href="/wiki/Cell_fusion" title="Cell fusion">fused</a> or <a href="/wiki/Hybrid_(biology)" title="Hybrid (biology)">hybridised</a> with the host.<a href="#cite_note-EU17-9">[9]</a> This relies on <a href="/wiki/Recombinant_DNA" title="Recombinant DNA">recombinant nucleic acid</a> techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a <a href="/wiki/Vector_(molecular_biology)" title="Vector (molecular biology)">vector</a> system or directly through <a href="/wiki/Microinjection" title="Microinjection">micro-injection</a>, macro-injection or <a href="/wiki/Micro-encapsulation" title="Micro-encapsulation">micro-encapsulation</a>. Genetic engineering does not normally include traditional breeding, <a href="/wiki/In_vitro_fertilisation" title="In vitro fertilisation">in vitro fertilisation</a>, induction of <a href="/wiki/Polyploidy" title="Polyploidy">polyploidy</a>, <a href="/wiki/Mutagenesis" title="Mutagenesis">mutagenesis</a> and cell fusion techniques that do not use recombinant <a href="/wiki/Nucleic_acid" title="Nucleic acid">nucleic acids</a> or a <a href="/wiki/Genetically_modified_organism" title="Genetically modified organism">genetically modified organism</a> in the process.<a href="#cite_note-EU17-9">[9]</a> However, some broad definitions of genetic engineering include <a href="/wiki/Selective_breeding" title="Selective breeding">selective breeding</a>.<a href="#cite_note-:2-10">[10]</a> <a href="/wiki/Cloning" title="Cloning">Cloning</a> and <a href="/wiki/Stem_cell" title="Stem cell">stem cell</a> research, although not considered genetic engineering,<a href="#cite_note-11">[11]</a> are closely related and genetic engineering can be used within them.<a href="#cite_note-12">[12]</a> <a href="/wiki/Synthetic_biology" title="Synthetic biology">Synthetic biology</a> is an emerging discipline that takes genetic engineering a step further by introducing artificially synthesised material into an organism.<a href="#cite_note-13">[13]</a> Plants, animals or microorganisms that have been changed through genetic engineering are termed <a href="/wiki/Genetically_modified_organism" title="Genetically modified organism">genetically modified organisms</a> or GMOs.<a href="#cite_note-14">[14]</a> If genetic material from another species is added to the host, the resulting organism is called <a href="/wiki/Transgenic" class="mw-redirect" title="Transgenic">transgenic</a>. If genetic material from the same species or a species that can naturally breed with the host is used the resulting organism is called <a href="/wiki/Cisgenic" class="mw-redirect" title="Cisgenic">cisgenic</a>.<a href="#cite_note-15">[15]</a> If genetic engineering is used to remove genetic material from the target organism the resulting organism is termed a <a href="/wiki/Gene_knockout" title="Gene knockout">knockout</a> organism.<a href="#cite_note-16">[16]</a> In Europe genetic modification is <a href="/wiki/Synonymous" class="mw-redirect" title="Synonymous">synonymous</a> with genetic engineering while within the United States of America and Canada genetic modification can also be used to refer to more conventional breeding methods.<a href="#cite_note-17">[17]</a><a href="#cite_note-18">[18]</a><a href="#cite_note-19">[19]</a> <div class="mw-heading mw-heading2"><h2 id="History">History</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=2" title="Edit section: History">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/History_of_genetic_engineering" title="History of genetic engineering">History of genetic engineering</a></div> Humans have altered the genomes of species for thousands of years through <a href="/wiki/Selective_breeding" title="Selective breeding">selective breeding</a>, or artificial selection<a href="#cite_note-Root-20">[20]</a>: 1 <a href="#cite_note-Zohary-21">[21]</a>: 1  as contrasted with <a href="/wiki/Natural_selection" title="Natural selection">natural selection</a>. More recently, <a href="/wiki/Mutation_breeding" title="Mutation breeding">mutation breeding</a> has used exposure to chemicals or radiation to produce a high frequency of random mutations, for selective breeding purposes. Genetic engineering as the direct manipulation of DNA by humans outside breeding and mutations has only existed since the 1970s. The term "genetic engineering" was coined by the Russian-born geneticist <a href="/wiki/Nikolay_Timofeev-Ressovsky" title="Nikolay Timofeev-Ressovsky">Nikolay Timofeev-Ressovsky</a> in his 1934 paper "The Experimental Production of Mutations", published in the British journal Biological Reviews.<a href="#cite_note-22">[22]</a> <a href="/wiki/Jack_Williamson" title="Jack Williamson">Jack Williamson</a> used the term in his science fiction novel Dragon's Island, published in 1951<a href="#cite_note-23">[23]</a> – one year before DNA's role in <a href="/wiki/Heredity" title="Heredity">heredity</a> was confirmed by <a href="/wiki/Alfred_Hershey" title="Alfred Hershey">Alfred Hershey</a> and <a href="/wiki/Martha_Chase" title="Martha Chase">Martha Chase</a>,<a href="#cite_note-24">[24]</a> and two years before <a href="/wiki/James_D._Watson" class="mw-redirect" title="James D. Watson">James Watson</a> and <a href="/wiki/Francis_Crick" title="Francis Crick">Francis Crick</a> showed that the <a href="/wiki/DNA" title="DNA">DNA</a> molecule has a double-helix structure – though the general concept of direct genetic manipulation was explored in rudimentary form in <a href="/wiki/Stanley_G._Weinbaum" title="Stanley G. Weinbaum">Stanley G. Weinbaum</a>'s 1936 science fiction story Proteus Island.<a href="#cite_note-25">[25]</a><a href="#cite_note-26">[26]</a> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Jaenisch_2003_by_Sam_Ogden.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Jaenisch_2003_by_Sam_Ogden.jpg/170px-Jaenisch_2003_by_Sam_Ogden.jpg" decoding="async" width="170" height="170" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Jaenisch_2003_by_Sam_Ogden.jpg/255px-Jaenisch_2003_by_Sam_Ogden.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Jaenisch_2003_by_Sam_Ogden.jpg/340px-Jaenisch_2003_by_Sam_Ogden.jpg 2x" data-file-width="1800" data-file-height="1800" /></a><figcaption>In 1974 <a href="/wiki/Rudolf_Jaenisch" title="Rudolf Jaenisch">Rudolf Jaenisch</a> created a <a href="/wiki/Genetically_modified_mouse" title="Genetically modified mouse">genetically modified mouse</a>, the first GM animal.</figcaption></figure> In 1972, <a href="/wiki/Paul_Berg" title="Paul Berg">Paul Berg</a> created the first <a href="/wiki/Recombinant_DNA" title="Recombinant DNA">recombinant DNA</a> molecules by combining DNA from the monkey virus <a href="/wiki/SV40" title="SV40">SV40</a> with that of the <a href="/wiki/Lambda_phage" title="Lambda phage">lambda virus</a>.<a href="#cite_note-27">[27]</a> In 1973 <a href="/wiki/Herbert_Boyer" title="Herbert Boyer">Herbert Boyer</a> and <a href="/wiki/Stanley_Norman_Cohen" title="Stanley Norman Cohen">Stanley Cohen</a> created the first <a href="/wiki/Transgenic_organism" class="mw-redirect" title="Transgenic organism">transgenic organism</a> by inserting <a href="/wiki/Antibiotic_resistance#Applications" class="mw-redirect" title="Antibiotic resistance">antibiotic resistance genes</a> into the <a href="/wiki/Plasmid" title="Plasmid">plasmid</a> of an <a href="/wiki/Escherichia_coli" title="Escherichia coli">Escherichia coli</a> bacterium.<a href="#cite_note-28">[28]</a><a href="#cite_note-29">[29]</a> A year later <a href="/wiki/Rudolf_Jaenisch" title="Rudolf Jaenisch">Rudolf Jaenisch</a> created a <a href="/wiki/Transgenic_mouse" class="mw-redirect" title="Transgenic mouse">transgenic mouse</a> by introducing foreign DNA into its embryo, making it the world's first <a href="/wiki/Transgenic_animal" class="mw-redirect" title="Transgenic animal">transgenic animal</a><a href="#cite_note-pmid4364530-30">[30]</a> These achievements led to concerns in the scientific community about potential risks from genetic engineering, which were first discussed in depth at the <a href="/wiki/Asilomar_Conference_on_Recombinant_DNA" title="Asilomar Conference on Recombinant DNA">Asilomar Conference</a> in 1975. One of the main recommendations from this meeting was that government oversight of recombinant DNA research should be established until the technology was deemed safe.<a href="#cite_note-ReferenceA-31">[31]</a><a href="#cite_note-32">[32]</a> In 1976 Genentech, the first genetic engineering company, was founded by Herbert Boyer and <a href="/wiki/Robert_A._Swanson" title="Robert A. Swanson">Robert Swanson</a> and a year later the company produced a human protein (<a href="/wiki/Somatostatin" title="Somatostatin">somatostatin</a>) in E. coli. Genentech announced the production of genetically engineered human <a href="/wiki/Insulin" title="Insulin">insulin</a> in 1978.<a href="#cite_note-:0-33">[33]</a> In 1980, the <a href="/wiki/U.S._Supreme_Court" class="mw-redirect" title="U.S. Supreme Court">U.S. Supreme Court</a> in the <a href="/wiki/Diamond_v._Chakrabarty" title="Diamond v. Chakrabarty">Diamond v. Chakrabarty</a> case ruled that genetically altered life could be patented.<a href="#cite_note-34">[34]</a> The <a href="/wiki/Insulin_(medication)" title="Insulin (medication)">insulin</a> produced by bacteria was approved for release by the <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">Food and Drug Administration</a> (FDA) in 1982.<a href="#cite_note-35">[35]</a> In 1983, a biotech company, Advanced Genetic Sciences (AGS) applied for U.S. government authorisation to perform field tests with the <a href="/wiki/Ice-minus_bacteria" title="Ice-minus bacteria">ice-minus strain</a> of <a href="/wiki/Pseudomonas_syringae" title="Pseudomonas syringae">Pseudomonas syringae</a> to protect crops from frost, but environmental groups and protestors delayed the field tests for four years with legal challenges.<a href="#cite_note-36">[36]</a> In 1987, the ice-minus strain of P. syringae became the first <a href="/wiki/Genetically_modified_organism" title="Genetically modified organism">genetically modified organism</a> (GMO) to be released into the environment<a href="#cite_note-BBC2002-37">[37]</a> when a strawberry field and a potato field in California were sprayed with it.<a href="#cite_note-38">[38]</a> Both test fields were attacked by activist groups the night before the tests occurred: "The world's first trial site attracted the world's first field trasher".<a href="#cite_note-BBC2002-37">[37]</a> The first field trials of <a href="/wiki/Transgenic_plants" class="mw-redirect" title="Transgenic plants">genetically engineered plants</a> occurred in France and the US in 1986, tobacco plants were engineered to be resistant to <a href="/wiki/Herbicide" title="Herbicide">herbicides</a>.<a href="#cite_note-39">[39]</a> The People's Republic of China was the first country to commercialise transgenic plants, introducing a virus-resistant tobacco in 1992.<a href="#cite_note-James1997-40">[40]</a> In 1994 <a href="/wiki/Monsanto#Spin-offs_and_mergers" title="Monsanto">Calgene</a> attained approval to commercially release the first <a href="/wiki/Genetically_modified_food" title="Genetically modified food">genetically modified food</a>, the <a href="/wiki/Flavr_Savr" title="Flavr Savr">Flavr Savr</a>, a tomato engineered to have a longer shelf life.<a href="#cite_note-41">[41]</a> In 1994, the European Union approved tobacco engineered to be resistant to the herbicide <a href="/wiki/Bromoxynil" title="Bromoxynil">bromoxynil</a>, making it the first genetically engineered crop commercialised in Europe.<a href="#cite_note-42">[42]</a> In 1995, <a href="/wiki/Genetically_modified_potato#NewLeaf" title="Genetically modified potato">Bt potato</a> was approved safe by the <a href="/wiki/Environmental_Protection_Agency" class="mw-redirect" title="Environmental Protection Agency">Environmental Protection Agency</a>, after having been approved by the FDA, making it the first pesticide producing crop to be approved in the US.<a href="#cite_note-43">[43]</a> In 2009 11 transgenic crops were grown commercially in 25 countries, the largest of which by area grown were the US, Brazil, Argentina, India, Canada, China, Paraguay and South Africa.<a href="#cite_note-44">[44]</a> In 2010, scientists at the <a href="/wiki/J._Craig_Venter_Institute" title="J. Craig Venter Institute">J. Craig Venter Institute</a> created the first <a href="/wiki/Synthetic_genome" class="mw-redirect" title="Synthetic genome">synthetic genome</a> and inserted it into an empty bacterial cell. The resulting bacterium, named <a href="/wiki/Mycoplasma_laboratorium" title="Mycoplasma laboratorium">Mycoplasma laboratorium</a>, could <a href="/wiki/Replicate_(biology)" title="Replicate (biology)">replicate</a> and produce proteins.<a href="#cite_note-45">[45]</a><a href="#cite_note-46">[46]</a> Four years later this was taken a step further when a bacterium was developed that replicated a <a href="/wiki/Plasmid" title="Plasmid">plasmid</a> containing a unique <a href="/wiki/Base_pair" title="Base pair">base pair</a>, creating the first organism engineered to use an expanded genetic alphabet.<a href="#cite_note-47">[47]</a><a href="#cite_note-48">[48]</a> In 2012, <a href="/wiki/Jennifer_Doudna" title="Jennifer Doudna">Jennifer Doudna</a> and <a href="/wiki/Emmanuelle_Charpentier" title="Emmanuelle Charpentier">Emmanuelle Charpentier</a> collaborated to develop the <a href="/wiki/CRISPR" title="CRISPR">CRISPR/Cas9</a> system,<a href="#cite_note-49">[49]</a><a href="#cite_note-50">[50]</a> a technique which can be used to easily and specifically alter the genome of almost any organism.<a href="#cite_note-51">[51]</a> <div class="mw-heading mw-heading2"><h2 id="Process">Process</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=3" title="Edit section: Process">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Genetic_engineering_techniques" title="Genetic engineering techniques">Genetic engineering techniques</a></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Master_Mix_with_Primers_form_PCR.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Master_Mix_with_Primers_form_PCR.jpg/170px-Master_Mix_with_Primers_form_PCR.jpg" decoding="async" width="170" height="227" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Master_Mix_with_Primers_form_PCR.jpg/255px-Master_Mix_with_Primers_form_PCR.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Master_Mix_with_Primers_form_PCR.jpg/340px-Master_Mix_with_Primers_form_PCR.jpg 2x" data-file-width="1200" data-file-height="1600" /></a><figcaption><a href="/wiki/Polymerase_chain_reaction" title="Polymerase chain reaction">Polymerase chain reaction</a> is a powerful tool used in <a href="/wiki/Molecular_cloning" title="Molecular cloning">molecular cloning</a>.</figcaption></figure> Creating a GMO is a multi-step process. Genetic engineers must first choose what gene they wish to insert into the organism. This is driven by what the aim is for the resultant organism and is built on earlier research. <a href="/wiki/Genetic_screen" title="Genetic screen">Genetic screens</a> can be carried out to determine potential genes and further tests then used to identify the best candidates. The development of <a href="/wiki/DNA_microarray" title="DNA microarray">microarrays</a>, <a href="/wiki/Transcriptomics" class="mw-redirect" title="Transcriptomics">transcriptomics</a> and <a href="/wiki/Whole_genome_sequencing" title="Whole genome sequencing">genome sequencing</a> has made it much easier to find suitable genes.<a href="#cite_note-52">[52]</a> Luck also plays its part; the <a href="/wiki/Roundup_Ready" title="Roundup Ready">Roundup Ready</a> gene was discovered after scientists noticed a bacterium thriving in the presence of the herbicide.<a href="#cite_note-53">[53]</a> <div class="mw-heading mw-heading3"><h3 id="Gene_isolation_and_cloning">Gene isolation and cloning</h3>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=4" title="Edit section: Gene isolation and cloning">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Molecular_cloning" title="Molecular cloning">Molecular cloning</a></div> The next step is to isolate the candidate gene. The <a href="/wiki/Cell_(biology)" title="Cell (biology)">cell</a> containing the gene is opened and the DNA is purified.<a href="#cite_note-54">[54]</a> The gene is separated by using <a href="/wiki/Restriction_enzymes" class="mw-redirect" title="Restriction enzymes">restriction enzymes</a> to cut the DNA into fragments<a href="#cite_note-55">[55]</a> or <a href="/wiki/Polymerase_chain_reaction" title="Polymerase chain reaction">polymerase chain reaction</a> (PCR) to amplify up the gene segment.<a href="#cite_note-56">[56]</a> These segments can then be extracted through <a href="/wiki/Gel_electrophoresis" title="Gel electrophoresis">gel electrophoresis</a>. If the chosen gene or the donor organism's <a href="/wiki/Genome" title="Genome">genome</a> has been well studied it may already be accessible from a <a href="/wiki/Library_(biology)" title="Library (biology)">genetic library</a>. If the <a href="/wiki/DNA_sequence" class="mw-redirect" title="DNA sequence">DNA sequence</a> is known, but no copies of the gene are available, it can also be <a href="/wiki/Gene_synthesis" class="mw-redirect" title="Gene synthesis">artificially synthesised</a>.<a href="#cite_note-57">[57]</a> Once isolated the gene is <a href="/wiki/Ligation_(molecular_biology)" title="Ligation (molecular biology)">ligated</a> into a <a href="/wiki/Plasmid" title="Plasmid">plasmid</a> that is then inserted into a bacterium. The plasmid is replicated when the bacteria divide, ensuring unlimited copies of the gene are available.<a href="#cite_note-58">[58]</a> The <a href="/wiki/RK2_plasmid" title="RK2 plasmid">RK2 plasmid</a> is notable for its ability to replicate in a wide variety of <a href="/wiki/Single-celled_organism" class="mw-redirect" title="Single-celled organism">single-celled organisms</a>, which makes it suitable as a genetic engineering tool.<a href="#cite_note-59">[59]</a> Before the gene is inserted into the target organism it must be combined with other genetic elements. These include a <a href="/wiki/Promoter_(biology)" class="mw-redirect" title="Promoter (biology)">promoter</a> and <a href="/wiki/Terminator_(genetics)" title="Terminator (genetics)">terminator</a> region, which initiate and end <a href="/wiki/Transcription_(genetics)" class="mw-redirect" title="Transcription (genetics)">transcription</a>. A <a href="/wiki/Selectable_marker" title="Selectable marker">selectable marker</a> gene is added, which in most cases confers <a href="/wiki/Antibiotic_resistance" class="mw-redirect" title="Antibiotic resistance">antibiotic resistance</a>, so researchers can easily determine which cells have been successfully transformed. The gene can also be modified at this stage for better expression or effectiveness. These manipulations are carried out using <a href="/wiki/Recombinant_DNA" title="Recombinant DNA">recombinant DNA</a> techniques, such as <a href="/wiki/Restriction_digest" title="Restriction digest">restriction digests</a>, ligations and molecular cloning.<a href="#cite_note-60">[60]</a> <div class="mw-heading mw-heading3"><h3 id="Inserting_DNA_into_the_host_genome">Inserting DNA into the host genome</h3>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=5" title="Edit section: Inserting DNA into the host genome">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Gene_delivery" title="Gene delivery">Gene delivery</a></div> <figure class="mw-default-size mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/File:Genegun.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d3/Genegun.jpg/170px-Genegun.jpg" decoding="async" width="170" height="227" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d3/Genegun.jpg/255px-Genegun.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d3/Genegun.jpg/340px-Genegun.jpg 2x" data-file-width="614" data-file-height="819" /></a><figcaption>A gene gun uses <a href="/wiki/Biolistics" class="mw-redirect" title="Biolistics">biolistics</a> to insert DNA into plant tissue.</figcaption></figure> There are a number of techniques used to insert genetic material into the host genome. Some bacteria can naturally <a href="/wiki/Competence_(biology)" class="mw-redirect" title="Competence (biology)">take up foreign DNA</a>. This ability can be induced in other bacteria via stress (e.g. <a href="/wiki/Heat_shock" class="mw-redirect" title="Heat shock">thermal</a> or electric shock), which increases the cell membrane's permeability to DNA; up-taken DNA can either integrate with the genome or exist as <a href="/wiki/Extrachromosomal_DNA" title="Extrachromosomal DNA">extrachromosomal DNA</a>. DNA is generally inserted into animal cells using <a href="/wiki/Microinjection" title="Microinjection">microinjection</a>, where it can be injected through the cell's <a href="/wiki/Nuclear_envelope" title="Nuclear envelope">nuclear envelope</a> directly into the <a href="/wiki/Cell_nucleus" title="Cell nucleus">nucleus</a>, or through the use of <a href="/wiki/Viral_vectors" class="mw-redirect" title="Viral vectors">viral vectors</a>.<a href="#cite_note-61">[61]</a> Plant genomes can be engineered by physical methods or by use of <a href="/wiki/Agrobacterium" title="Agrobacterium">Agrobacterium</a> for the delivery of sequences hosted in <a href="/wiki/Transfer_DNA_binary_system" title="Transfer DNA binary system">T-DNA binary vectors</a>. In plants the DNA is often inserted using <a href="/wiki/Agrobacterium#Uses_in_biotechnology" title="Agrobacterium">Agrobacterium-mediated transformation</a>,<a href="#cite_note-62">[62]</a> taking advantage of the Agrobacteriums <a href="/wiki/Transfer_DNA" title="Transfer DNA">T-DNA</a> sequence that allows natural insertion of genetic material into plant cells.<a href="#cite_note-63">[63]</a> Other methods include <a href="/wiki/Biolistics" class="mw-redirect" title="Biolistics">biolistics</a>, where particles of gold or tungsten are coated with DNA and then shot into young plant cells,<a href="#cite_note-64">[64]</a> and <a href="/wiki/Electroporation" title="Electroporation">electroporation</a>, which involves using an electric shock to make the cell membrane permeable to plasmid DNA. As only a single cell is transformed with genetic material, the organism must be <a href="/wiki/Regeneration_(biology)" title="Regeneration (biology)">regenerated</a> from that single cell. In plants this is accomplished through the use of <a href="/wiki/Plant_tissue_culture" title="Plant tissue culture">tissue culture</a>.<a href="#cite_note-65">[65]</a><a href="#cite_note-66">[66]</a> In animals it is necessary to ensure that the inserted DNA is present in the <a href="/wiki/Embryonic_stem_cells" class="mw-redirect" title="Embryonic stem cells">embryonic stem cells</a>.<a href="#cite_note-67">[67]</a> Bacteria consist of a single cell and reproduce clonally so regeneration is not necessary. <a href="/wiki/Selectable_markers" class="mw-redirect" title="Selectable markers">Selectable markers</a> are used to easily differentiate transformed from untransformed cells. These markers are usually present in the transgenic organism, although a number of strategies have been developed that can remove the selectable marker from the mature transgenic plant.<a href="#cite_note-68">[68]</a> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Agrobacterium-tumefaciens.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/ae/Agrobacterium-tumefaciens.png/170px-Agrobacterium-tumefaciens.png" decoding="async" width="170" height="215" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/a/ae/Agrobacterium-tumefaciens.png 1.5x" data-file-width="187" data-file-height="237" /></a><figcaption><a href="/wiki/A._tumefaciens" class="mw-redirect" title="A. tumefaciens">A. tumefaciens</a> attaching itself to a carrot cell</figcaption></figure> Further testing using PCR, <a href="/wiki/Southern_hybridization" class="mw-redirect" title="Southern hybridization">Southern hybridization</a>, and <a href="/wiki/DNA_sequencing" title="DNA sequencing">DNA sequencing</a> is conducted to confirm that an organism contains the new gene.<a href="#cite_note-69">[69]</a> These tests can also confirm the chromosomal location and copy number of the inserted gene. The presence of the gene does not guarantee it will be <a href="/wiki/Gene_expression" title="Gene expression">expressed</a> at appropriate levels in the target tissue so methods that look for and measure the gene products (RNA and protein) are also used. These include <a href="/wiki/Northern_hybridization" class="mw-redirect" title="Northern hybridization">northern hybridisation</a>, quantitative <a href="/wiki/RT-PCR" class="mw-redirect" title="RT-PCR">RT-PCR</a>, <a href="/wiki/Western_blot" title="Western blot">Western blot</a>, <a href="/wiki/Immunofluorescence" title="Immunofluorescence">immunofluorescence</a>, <a href="/wiki/ELISA" title="ELISA">ELISA</a> and phenotypic analysis.<a href="#cite_note-70">[70]</a> The new genetic material can be inserted randomly within the host genome or targeted to a specific location. The technique of <a href="/wiki/Gene_targeting" title="Gene targeting">gene targeting</a> uses <a href="/wiki/Homologous_recombination" title="Homologous recombination">homologous recombination</a> to make desired changes to a specific <a href="/wiki/Endogenous" class="mw-redirect" title="Endogenous">endogenous</a> gene. This tends to occur at a relatively low frequency in plants and animals and generally requires the use of <a href="/wiki/Selectable_markers" class="mw-redirect" title="Selectable markers">selectable markers</a>. The frequency of gene targeting can be greatly enhanced through <a href="/wiki/Genome_editing" title="Genome editing">genome editing</a>. Genome editing uses artificially engineered <a href="/wiki/Nuclease" title="Nuclease">nucleases</a> that create specific <a href="/wiki/Double-strand_breaks" class="mw-redirect" title="Double-strand breaks">double-stranded breaks</a> at desired locations in the genome, and use the cell's endogenous mechanisms to repair the induced break by the natural processes of <a href="/wiki/Homologous_recombination" title="Homologous recombination">homologous recombination</a> and <a href="/wiki/Nonhomologous_end_joining" class="mw-redirect" title="Nonhomologous end joining">nonhomologous end-joining</a>. There are four families of engineered nucleases: <a href="/wiki/Meganuclease" title="Meganuclease">meganucleases</a>,<a href="#cite_note-71">[71]</a><a href="#cite_note-72">[72]</a> <a href="/wiki/Zinc_finger_nuclease" class="mw-redirect" title="Zinc finger nuclease">zinc finger nucleases</a>,<a href="#cite_note-73">[73]</a><a href="#cite_note-74">[74]</a> <a href="/wiki/Transcription_activator-like_effector_nuclease" title="Transcription activator-like effector nuclease">transcription activator-like effector nucleases</a> (TALENs),<a href="#cite_note-75">[75]</a><a href="#cite_note-76">[76]</a> and the Cas9-guideRNA system (adapted from <a href="/wiki/CRISPR_gene_editing" title="CRISPR gene editing">CRISPR</a>).<a href="#cite_note-77">[77]</a><a href="#cite_note-78">[78]</a> TALEN and CRISPR are the two most commonly used and each has its own advantages.<a href="#cite_note-:5-79">[79]</a> TALENs have greater target specificity, while CRISPR is easier to design and more efficient.<a href="#cite_note-:5-79">[79]</a> In addition to enhancing gene targeting, engineered nucleases can be used to introduce mutations at endogenous genes that generate a <a href="/wiki/Gene_knockout" title="Gene knockout">gene knockout</a>.<a href="#cite_note-80">[80]</a><a href="#cite_note-81">[81]</a> <div class="mw-heading mw-heading2"><h2 id="Applications">Applications</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=6" title="Edit section: Applications">edit</a>]</div> Genetic engineering has applications in medicine, research, industry and agriculture and can be used on a wide range of plants, animals and microorganisms. <a href="/wiki/Bacteria" title="Bacteria">Bacteria</a>, the first organisms to be genetically modified, can have plasmid DNA inserted containing new genes that code for medicines or enzymes that process food and other <a href="/wiki/Enzyme_substrate_(biology)" class="mw-redirect" title="Enzyme substrate (biology)">substrates</a>.<a href="#cite_note-82">[82]</a><a href="#cite_note-83">[83]</a> Plants have been modified for insect protection, <a href="/wiki/Herbicide_resistance" class="mw-redirect" title="Herbicide resistance">herbicide resistance</a>, virus resistance, enhanced nutrition, tolerance to environmental pressures and the production of <a href="/wiki/Edible_vaccines" class="mw-redirect" title="Edible vaccines">edible vaccines</a>.<a href="#cite_note-84">[84]</a> Most commercialised GMOs are insect resistant or herbicide tolerant crop plants.<a href="#cite_note-85">[85]</a> Genetically modified animals have been used for research, model animals and the production of agricultural or pharmaceutical products. The genetically modified animals include animals with <a href="/wiki/Knock-out_mice" class="mw-redirect" title="Knock-out mice">genes knocked out</a>, <a href="/wiki/Oncomouse" title="Oncomouse">increased susceptibility to disease</a>, hormones for extra growth and the ability to express proteins in their milk.<a href="#cite_note-86">[86]</a> <div class="mw-heading mw-heading3"><h3 id="Medicine">Medicine</h3>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=7" title="Edit section: Medicine">edit</a>]</div> Genetic engineering has many applications to medicine that include the manufacturing of drugs, creation of <a href="/wiki/Model_organism" title="Model organism">model animals</a> that mimic human conditions and <a href="/wiki/Gene_therapy" title="Gene therapy">gene therapy</a>. One of the earliest uses of genetic engineering was to mass-produce human insulin in bacteria.<a href="#cite_note-:0-33">[33]</a> This application has now been applied to human <a href="/wiki/Growth_hormone" title="Growth hormone">growth hormones</a>, <a href="/wiki/Follicle-stimulating_hormone" title="Follicle-stimulating hormone">follicle stimulating hormones</a> (for treating infertility), <a href="/wiki/Albumin_human" class="mw-redirect" title="Albumin human">human albumin</a>, <a href="/wiki/Monoclonal_antibodies" class="mw-redirect" title="Monoclonal antibodies">monoclonal antibodies</a>, <a href="/wiki/Antihemophilic_factor" class="mw-redirect" title="Antihemophilic factor">antihemophilic factors</a>, <a href="/wiki/Vaccine" title="Vaccine">vaccines</a> and many other drugs.<a href="#cite_note-87">[87]</a><a href="#cite_note-88">[88]</a> Mouse <a href="/wiki/Hybridoma_technology" title="Hybridoma technology">hybridomas</a>, cells fused together to create <a href="/wiki/Monoclonal_antibodies" class="mw-redirect" title="Monoclonal antibodies">monoclonal antibodies</a>, have been adapted through genetic engineering to create human monoclonal antibodies.<a href="#cite_note-89">[89]</a> <a href="/wiki/Genetically_engineered_virus" class="mw-redirect" title="Genetically engineered virus">Genetically engineered viruses</a> are being developed that can still confer immunity, but lack the <a href="/wiki/Infectious_Disease" class="mw-redirect" title="Infectious Disease">infectious</a> <a href="/wiki/DNA_sequence" class="mw-redirect" title="DNA sequence">sequences</a>.<a href="#cite_note-90">[90]</a> Genetic engineering is also used to create animal models of human diseases. <a href="/wiki/Genetically_modified_mouse" title="Genetically modified mouse">Genetically modified mice</a> are the most common genetically engineered animal model.<a href="#cite_note-91">[91]</a> They have been used to study and model cancer (the <a href="/wiki/Oncomouse" title="Oncomouse">oncomouse</a>), obesity, heart disease, diabetes, arthritis, substance abuse, anxiety, aging and Parkinson disease.<a href="#cite_note-92">[92]</a> Potential cures can be tested against these mouse models. Gene therapy is the <a href="/wiki/Human_genetic_engineering" class="mw-redirect" title="Human genetic engineering">genetic engineering of humans</a>, generally by replacing defective genes with effective ones. <a href="/wiki/Clinical_research" title="Clinical research">Clinical research</a> using <a href="/wiki/Somatic_(biology)" title="Somatic (biology)">somatic</a> gene therapy has been conducted with several diseases, including <a href="/wiki/X-linked_severe_combined_immunodeficiency" title="X-linked severe combined immunodeficiency">X-linked SCID</a>,<a href="#cite_note-93">[93]</a> <a href="/wiki/Chronic_lymphocytic_leukemia" title="Chronic lymphocytic leukemia">chronic lymphocytic leukemia</a> (CLL),<a href="#cite_note-Porter-94">[94]</a><a href="#cite_note-95">[95]</a> and <a href="/wiki/Parkinson%27s_disease" title="Parkinson's disease">Parkinson's disease</a>.<a href="#cite_note-96">[96]</a> In 2012, <a href="/wiki/Alipogene_tiparvovec" title="Alipogene tiparvovec">Alipogene tiparvovec</a> became the first gene therapy treatment to be approved for clinical use.<a href="#cite_note-Gallagher-97">[97]</a><a href="#cite_note-Richards2012-98">[98]</a> In 2015 a virus was used to insert a healthy gene into the skin cells of a boy suffering from a rare skin disease, <a href="/wiki/Epidermolysis_bullosa" title="Epidermolysis bullosa">epidermolysis bullosa</a>, in order to grow, and then graft healthy skin onto 80 percent of the boy's body which was affected by the illness.<a href="#cite_note-99">[99]</a> <a href="/wiki/Germline" title="Germline">Germline</a> gene therapy would result in any change being inheritable, which has raised concerns within the scientific community.<a href="#cite_note-100">[100]</a><a href="#cite_note-101">[101]</a> In 2015, CRISPR was used to edit the DNA of non-viable <a href="/wiki/Human_embryos" class="mw-redirect" title="Human embryos">human embryos</a>,<a href="#cite_note-NYT-20150423-102">[102]</a><a href="#cite_note-PC-20150418-103">[103]</a> leading scientists of major world academies to call for a moratorium on inheritable human genome edits.<a href="#cite_note-NYT-20151203-nw-104">[104]</a> There are also concerns that the technology could be used not just for treatment, but for enhancement, modification or alteration of a human beings' appearance, adaptability, intelligence, character or behavior.<a href="#cite_note-105">[105]</a> The distinction between cure and enhancement can also be difficult to establish.<a href="#cite_note-106">[106]</a> In November 2018, <a href="/wiki/He_Jiankui" title="He Jiankui">He Jiankui</a> announced that he had <a href="/wiki/Genome_editing" title="Genome editing">edited the genomes</a> of two human embryos, to attempt to disable the <a href="/wiki/CCR5" title="CCR5">CCR5</a> gene, which codes for a receptor that <a href="/wiki/HIV" title="HIV">HIV</a> uses to enter cells. The work was widely condemned as unethical, dangerous, and premature.<a href="#cite_note-107">[107]</a> Currently, germline modification is banned in 40 countries. Scientists that do this type of research will often let embryos grow for a few days without allowing it to develop into a baby.<a href="#cite_note-108">[108]</a> Researchers are altering the genome of pigs to induce the growth of human organs, with the aim of increasing the success of <a href="/wiki/Xenotransplantation" title="Xenotransplantation">pig to human organ transplantation</a>.<a href="#cite_note-Medical_News_Today-109">[109]</a> Scientists are creating "gene drives", changing the genomes of mosquitoes to make them immune to malaria, and then looking to spread the genetically altered mosquitoes throughout the mosquito population in the hopes of eliminating the disease.<a href="#cite_note-110">[110]</a> <div class="mw-heading mw-heading3"><h3 id="Research">Research</h3>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=8" title="Edit section: Research">edit</a>]</div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:PCWmice1.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/0/04/PCWmice1.jpg" decoding="async" width="200" height="97" class="mw-file-element" data-file-width="200" data-file-height="97" /></a><figcaption><a href="/wiki/Knockout_mouse" title="Knockout mouse">Knockout mice</a></figcaption></figure> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Expression_of_Human_Wild-Type_and_P239S_Mutant_Palladin.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/56/Expression_of_Human_Wild-Type_and_P239S_Mutant_Palladin.png/220px-Expression_of_Human_Wild-Type_and_P239S_Mutant_Palladin.png" decoding="async" width="220" height="293" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/56/Expression_of_Human_Wild-Type_and_P239S_Mutant_Palladin.png/330px-Expression_of_Human_Wild-Type_and_P239S_Mutant_Palladin.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/56/Expression_of_Human_Wild-Type_and_P239S_Mutant_Palladin.png/440px-Expression_of_Human_Wild-Type_and_P239S_Mutant_Palladin.png 2x" data-file-width="450" data-file-height="600" /></a><figcaption>Human cells in which some proteins are fused with <a href="/wiki/Green_fluorescent_protein" title="Green fluorescent protein">green fluorescent protein</a> to allow them to be visualised</figcaption></figure> Genetic engineering is an important tool for <a href="/wiki/Natural_scientists" class="mw-redirect" title="Natural scientists">natural scientists</a>, with the creation of transgenic organisms one of the most important tools for analysis of gene function.<a href="#cite_note-111">[111]</a> Genes and other genetic information from a wide range of organisms can be inserted into bacteria for storage and modification, creating <a href="/wiki/Genetically_modified_bacteria" title="Genetically modified bacteria">genetically modified bacteria</a> in the process. Bacteria are cheap, easy to grow, <a href="/wiki/Clone_(cell_biology)" title="Clone (cell biology)">clonal</a>, multiply quickly, relatively easy to transform and can be stored at -80 °C almost indefinitely. Once a gene is isolated it can be stored inside the bacteria providing an unlimited supply for research.<a href="#cite_note-112">[112]</a> Organisms are genetically engineered to discover the functions of certain genes. This could be the effect on the phenotype of the organism, where the gene is expressed or what other genes it interacts with. These experiments generally involve loss of function, gain of function, tracking and expression. <ul><li>Loss of function experiments, such as in a <a href="/wiki/Gene_knockout" title="Gene knockout">gene knockout</a> experiment, in which an organism is engineered to lack the activity of one or more genes. In a simple knockout a copy of the desired gene has been altered to make it non-functional. <a href="/wiki/Embryonic_stem_cells" class="mw-redirect" title="Embryonic stem cells">Embryonic stem cells</a> incorporate the altered gene, which replaces the already present functional copy. These stem cells are injected into <a href="/wiki/Blastocyst" title="Blastocyst">blastocysts</a>, which are implanted into surrogate mothers. This allows the experimenter to analyse the defects caused by this <a href="/wiki/Mutation" title="Mutation">mutation</a> and thereby determine the role of particular genes. It is used especially frequently in <a href="/wiki/Developmental_biology" title="Developmental biology">developmental biology</a>.<a href="#cite_note-:3-113">[113]</a> When this is done by creating a library of genes with point mutations at every position in the area of interest, or even every position in the whole gene, this is called "scanning mutagenesis". The simplest method, and the first to be used, is "alanine scanning", where every position in turn is mutated to the unreactive amino acid <a href="/wiki/Alanine" title="Alanine">alanine</a>.<a href="#cite_note-114">[114]</a></li> <li>Gain of function experiments, the logical counterpart of knockouts. These are sometimes performed in conjunction with knockout experiments to more finely establish the function of the desired gene. The process is much the same as that in knockout engineering, except that the construct is designed to increase the function of the gene, usually by providing extra copies of the gene or inducing synthesis of the protein more frequently. Gain of function is used to tell whether or not a protein is sufficient for a function, but does not always mean it is required, especially when dealing with genetic or functional redundancy.<a href="#cite_note-:3-113">[113]</a></li> <li>Tracking experiments, which seek to gain information about the localisation and interaction of the desired protein. One way to do this is to replace the wild-type gene with a 'fusion' gene, which is a juxtaposition of the wild-type gene with a reporting element such as <a href="/wiki/Green_fluorescent_protein" title="Green fluorescent protein">green fluorescent protein</a> (GFP) that will allow easy visualisation of the products of the genetic modification. While this is a useful technique, the manipulation can destroy the function of the gene, creating secondary effects and possibly calling into question the results of the experiment. More sophisticated techniques are now in development that can track protein products without mitigating their function, such as the addition of small sequences that will serve as binding motifs to monoclonal antibodies.<a href="#cite_note-:3-113">[113]</a></li> <li>Expression studies aim to discover where and when specific proteins are produced. In these experiments, the DNA sequence before the DNA that codes for a protein, known as a gene's <a href="/wiki/Promoter_(biology)" class="mw-redirect" title="Promoter (biology)">promoter</a>, is reintroduced into an organism with the protein coding region replaced by a reporter gene such as GFP or an enzyme that catalyses the production of a dye. Thus the time and place where a particular protein is produced can be observed. Expression studies can be taken a step further by altering the promoter to find which pieces are crucial for the proper expression of the gene and are actually bound by transcription factor proteins; this process is known as <a href="/wiki/Promoter_bashing" title="Promoter bashing">promoter bashing</a>.<a href="#cite_note-115">[115]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Industrial">Industrial</h3>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=9" title="Edit section: Industrial">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Industrial_microbiology" title="Industrial microbiology">Industrial microbiology</a></div>Organisms can have their cells transformed with a gene coding for a useful protein, such as an enzyme, so that they will <a href="/wiki/Protein_expression_(biotechnology)" class="mw-redirect" title="Protein expression (biotechnology)">overexpress</a> the desired protein. Mass quantities of the protein can then be manufactured by growing the transformed organism in <a href="/wiki/Bioreactor" title="Bioreactor">bioreactor</a> equipment using <a href="/wiki/Industrial_fermentation" title="Industrial fermentation">industrial fermentation</a>, and then <a href="/wiki/Protein_purification" title="Protein purification">purifying</a> the protein.<a href="#cite_note-116">[116]</a> Some genes do not work well in bacteria, so yeast, insect cells or mammalian cells can also be used.<a href="#cite_note-117">[117]</a> These techniques are used to produce medicines such as <a href="/wiki/Insulin" title="Insulin">insulin</a>, <a href="/wiki/Human_growth_hormone" class="mw-redirect" title="Human growth hormone">human growth hormone</a>, and <a href="/wiki/Vaccine" title="Vaccine">vaccines</a>, supplements such as <a href="/wiki/Tryptophan" title="Tryptophan">tryptophan</a>, aid in the production of food (<a href="/wiki/Chymosin" title="Chymosin">chymosin</a> in cheese making) and fuels.<a href="#cite_note-118">[118]</a> Other applications with genetically engineered bacteria could involve making them perform tasks outside their natural cycle, such as making <a href="/wiki/Biofuel" title="Biofuel">biofuels</a>,<a href="#cite_note-119">[119]</a> cleaning up oil spills, carbon and other toxic waste<a href="#cite_note-120">[120]</a> and detecting arsenic in drinking water.<a href="#cite_note-121">[121]</a> Certain genetically modified microbes can also be used in <a href="/wiki/Biomining" title="Biomining">biomining</a> and <a href="/wiki/Bioremediation" title="Bioremediation">bioremediation</a>, due to their ability to extract heavy metals from their environment and incorporate them into compounds that are more easily recoverable.<a href="#cite_note-122">[122]</a> In <a href="/wiki/Materials_science" title="Materials science">materials science</a>, a genetically modified virus has been used in a research laboratory as a scaffold for assembling a more environmentally friendly <a href="/wiki/Lithium-ion_battery" title="Lithium-ion battery">lithium-ion battery</a>.<a href="#cite_note-123">[123]</a><a href="#cite_note-124">[124]</a> Bacteria have also been engineered to function as sensors by expressing a fluorescent protein under certain environmental conditions.<a href="#cite_note-125">[125]</a> <div class="mw-heading mw-heading3"><h3 id="Agriculture">Agriculture</h3>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=10" title="Edit section: Agriculture">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main articles: <a href="/wiki/Genetically_modified_crops" title="Genetically modified crops">Genetically modified crops</a> and <a href="/wiki/Genetically_modified_food" title="Genetically modified food">Genetically modified food</a></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Bt_plants.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/1/1d/Bt_plants.png/170px-Bt_plants.png" decoding="async" width="170" height="310" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/1d/Bt_plants.png/255px-Bt_plants.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/1d/Bt_plants.png/340px-Bt_plants.png 2x" data-file-width="715" data-file-height="1302" /></a><figcaption>Bt-toxins present in <a href="/wiki/Peanut" title="Peanut">peanut</a> leaves (bottom image) protect it from extensive damage caused by <a href="/wiki/Lesser_cornstalk_borer" class="mw-redirect" title="Lesser cornstalk borer">lesser cornstalk borer</a> <a href="/wiki/Larva" title="Larva">larvae</a> (top image).<a href="#cite_note-126">[126]</a></figcaption></figure> One of the best-known and <a href="/wiki/Genetically_modified_food_controversies" title="Genetically modified food controversies">controversial</a> applications of genetic engineering is the creation and use of <a href="/wiki/Genetically_modified_crops" title="Genetically modified crops">genetically modified crops</a> or <a href="/wiki/Genetically_modified_livestock" class="mw-redirect" title="Genetically modified livestock">genetically modified livestock</a> to produce <a href="/wiki/Genetically_modified_food" title="Genetically modified food">genetically modified food</a>. Crops have been developed to increase production, increase tolerance to <a href="/wiki/Abiotic_stress" title="Abiotic stress">abiotic stresses</a>, alter the composition of the food, or to produce novel products.<a href="#cite_note-127">[127]</a> The first crops to be released commercially on a large scale provided protection from insect pests or tolerance to <a href="/wiki/Herbicides" class="mw-redirect" title="Herbicides">herbicides</a>. Fungal and virus resistant crops have also been developed or are in development.<a href="#cite_note-128">[128]</a><a href="#cite_note-129">[129]</a> This makes the insect and weed management of crops easier and can indirectly increase crop yield.<a href="#cite_note-130">[130]</a><a href="#cite_note-Biodiversity-131">[131]</a> GM crops that directly improve yield by accelerating growth or making the plant more hardy (by improving salt, cold or drought tolerance) are also under development.<a href="#cite_note-Deborah_B._Whitman_2000-132">[132]</a> In 2016 <a href="/wiki/AquAdvantage_salmon" title="AquAdvantage salmon">Salmon</a> have been genetically modified with growth hormones to reach normal adult size much faster.<a href="#cite_note-Genetically_Engineered_Salmon-133">[133]</a> GMOs have been developed that modify the quality of produce by increasing the nutritional value or providing more industrially useful qualities or quantities.<a href="#cite_note-Deborah_B._Whitman_2000-132">[132]</a> The <a href="/wiki/Amflora" title="Amflora">Amflora</a> potato produces a more industrially useful blend of starches. <a href="/wiki/Genetically_modified_soybean" title="Genetically modified soybean">Soybeans</a> and <a href="/wiki/Genetically_modified_canola" title="Genetically modified canola">canola</a> have been genetically modified to produce more healthy oils.<a href="#cite_note-134">[134]</a><a href="#cite_note-135">[135]</a> The first commercialised GM food was a <a href="/wiki/Flavr_Savr" title="Flavr Savr">tomato</a> that had delayed ripening, increasing its <a href="/wiki/Shelf_life" title="Shelf life">shelf life</a>.<a href="#cite_note-136">[136]</a> Plants and animals have been engineered to produce materials they do not normally make. <a href="/wiki/Pharming_(genetics)" title="Pharming (genetics)">Pharming</a> uses crops and animals as bioreactors to produce vaccines, drug intermediates, or the drugs themselves; the useful product is purified from the harvest and then used in the standard pharmaceutical production process.<a href="#cite_note-137">[137]</a> Cows and goats have been engineered to express drugs and other proteins in their milk, and in 2009 the FDA approved a drug produced in goat milk.<a href="#cite_note-138">[138]</a><a href="#cite_note-139">[139]</a> <div class="mw-heading mw-heading3"><h3 id="Other_applications">Other applications</h3>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=11" title="Edit section: Other applications">edit</a>]</div> Genetic engineering has potential applications in conservation and natural area management. Gene transfer through <a href="/wiki/Viral_vector" title="Viral vector">viral vectors</a> has been proposed as a means of controlling invasive species as well as vaccinating threatened fauna from disease.<a href="#cite_note-140">[140]</a> Transgenic trees have been suggested as a way to confer resistance to pathogens in wild populations.<a href="#cite_note-141">[141]</a> With the increasing risks of <a href="/wiki/Maladaptation" title="Maladaptation">maladaptation</a> in organisms as a result of <a href="/wiki/Climate_change" title="Climate change">climate change</a> and other perturbations, facilitated adaptation through gene tweaking could be one solution to reducing extinction risks.<a href="#cite_note-142">[142]</a> Applications of genetic engineering in conservation are thus far mostly theoretical and have yet to be put into practice. Genetic engineering is also being used to create <a href="/wiki/Microbial_art" title="Microbial art">microbial art</a>.<a href="#cite_note-143">[143]</a> Some bacteria have been genetically engineered to create black and white photographs.<a href="#cite_note-144">[144]</a> Novelty items such as lavender-colored <a href="/wiki/Dianthus_caryophyllus#Colors" title="Dianthus caryophyllus">carnations</a>,<a href="#cite_note-physorg-145">[145]</a> <a href="/wiki/Blue_rose" title="Blue rose">blue roses</a>,<a href="#cite_note-146">[146]</a> and <a href="/wiki/GloFish" title="GloFish">glowing fish</a>,<a href="#cite_note-147">[147]</a><a href="#cite_note-148">[148]</a> have also been produced through genetic engineering. <div class="mw-heading mw-heading2"><h2 id="Regulation">Regulation</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=12" title="Edit section: Regulation">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Regulation_of_genetic_engineering" title="Regulation of genetic engineering">Regulation of genetic engineering</a></div> The regulation of genetic engineering concerns the approaches taken by governments to assess and manage the risks associated with the development and release of GMOs. The development of a regulatory framework began in 1975, at <a href="/wiki/Asilomar_Conference_Grounds" title="Asilomar Conference Grounds">Asilomar</a>, California.<a href="#cite_note-149">[149]</a> The <a href="/wiki/Asilomar_conference_on_recombinant_DNA" class="mw-redirect" title="Asilomar conference on recombinant DNA">Asilomar meeting</a> recommended a set of voluntary guidelines regarding the use of recombinant technology.<a href="#cite_note-ReferenceA-31">[31]</a> As the technology improved the US established a committee at the <a href="/wiki/Office_of_Science_and_Technology_Policy" title="Office of Science and Technology Policy">Office of Science and Technology</a>,<a href="#cite_note-McHughen2007-150">[150]</a> which assigned regulatory approval of GM food to the USDA, FDA and EPA.<a href="#cite_note-:7-151">[151]</a> The <a href="/wiki/Cartagena_Protocol_on_Biosafety" title="Cartagena Protocol on Biosafety">Cartagena Protocol on Biosafety</a>, an international treaty that governs the transfer, handling, and use of GMOs,<a href="#cite_note-152">[152]</a> was adopted on 29 January 2000.<a href="#cite_note-153">[153]</a> One hundred and fifty-seven countries are members of the Protocol, and many use it as a reference point for their own regulations.<a href="#cite_note-Kimani-154">[154]</a> The legal and regulatory status of GM foods varies by country, with some nations banning or restricting them, and others permitting them with widely differing degrees of regulation.<a href="#cite_note-155">[155]</a><a href="#cite_note-156">[156]</a><a href="#cite_note-157">[157]</a><a href="#cite_note-158">[158]</a> Some countries allow the import of GM food with authorisation, but either do not allow its cultivation (Russia, Norway, Israel) or have provisions for cultivation even though no GM products are yet produced (Japan, South Korea). Most countries that do not allow GMO cultivation do permit research.<a href="#cite_note-159">[159]</a> Some of the most marked differences occur between the US and Europe. The US policy focuses on the product (not the process), only looks at verifiable scientific risks and uses the concept of <a href="/wiki/Substantial_equivalence" title="Substantial equivalence">substantial equivalence</a>.<a href="#cite_note-Marsen-160">[160]</a> The <a href="/wiki/European_Union" title="European Union">European Union</a> by contrast has possibly the most stringent GMO regulations in the world.<a href="#cite_note-Davison2010-161">[161]</a> All GMOs, along with <a href="/wiki/Irradiated_food" class="mw-redirect" title="Irradiated food">irradiated food</a>, are considered "new food" and subject to extensive, case-by-case, science-based food evaluation by the <a href="/wiki/European_Food_Safety_Authority" title="European Food Safety Authority">European Food Safety Authority</a>. The criteria for authorisation fall in four broad categories: "safety", "freedom of choice", "labelling", and "traceability".<a href="#cite_note-:8-162">[162]</a> The level of regulation in other countries that cultivate GMOs lie in between Europe and the United States. <table class="wikitable"> <caption>Regulatory agencies by geographical region </caption> <tbody><tr> <th>Region </th> <th>Regulators </th> <th>Notes </th></tr> <tr> <td>US </td> <td><a href="/wiki/United_States_Department_of_Agriculture" title="United States Department of Agriculture">USDA</a>, <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">FDA</a> and <a href="/wiki/United_States_Environmental_Protection_Agency" title="United States Environmental Protection Agency">EPA</a><a href="#cite_note-:7-151">[151]</a> </td> <td> </td></tr> <tr> <td>Europe </td> <td><a href="/wiki/European_Food_Safety_Authority" title="European Food Safety Authority">European Food Safety Authority</a><a href="#cite_note-:8-162">[162]</a> </td> <td> </td></tr> <tr> <td>Canada </td> <td><a href="/wiki/Health_Canada" title="Health Canada">Health Canada</a> and the <a href="/wiki/Canadian_Food_Inspection_Agency" title="Canadian Food Inspection Agency">Canadian Food Inspection Agency</a><a href="#cite_note-163">[163]</a><a href="#cite_note-164">[164]</a> </td> <td>Regulated products with novel features regardless of method of origin<a href="#cite_note-165">[165]</a><a href="#cite_note-166">[166]</a> </td></tr> <tr> <td>Africa </td> <td><a href="/wiki/Common_Market_for_Eastern_and_Southern_Africa" title="Common Market for Eastern and Southern Africa">Common Market for Eastern and Southern Africa</a><a href="#cite_note-:4-167">[167]</a> </td> <td>Final decision lies with each individual country.<a href="#cite_note-:4-167">[167]</a> </td></tr> <tr> <td>China </td> <td>Office of Agricultural Genetic Engineering Biosafety Administration<a href="#cite_note-168">[168]</a> </td> <td> </td></tr> <tr> <td>India </td> <td>Institutional Biosafety Committee, Review Committee on Genetic Manipulation and Genetic Engineering Approval Committee<a href="#cite_note-169">[169]</a> </td> <td> </td></tr> <tr> <td>Argentina </td> <td>National Agricultural Biotechnology Advisory Committee (environmental impact), the National Service of Health and Agrifood Quality (food safety) and the National Agribusiness Direction (effect on trade)<a href="#cite_note-BASFppt-170">[170]</a> </td> <td>Final decision made by the Secretariat of Agriculture, Livestock, Fishery and Food.<a href="#cite_note-BASFppt-170">[170]</a> </td></tr> <tr> <td>Brazil </td> <td>National Biosafety Technical Commission (environmental and food safety) and the Council of Ministers (commercial and economical issues)<a href="#cite_note-BASFppt-170">[170]</a> </td> <td> </td></tr> <tr> <td>Australia </td> <td><a href="/wiki/Office_of_the_Gene_Technology_Regulator" title="Office of the Gene Technology Regulator">Office of the Gene Technology Regulator</a> (oversees all GM products), <a href="/wiki/Therapeutic_Goods_Administration" title="Therapeutic Goods Administration">Therapeutic Goods Administration</a> (GM medicines) and <a href="/wiki/Food_Standards_Australia_New_Zealand" title="Food Standards Australia New Zealand">Food Standards Australia New Zealand</a> (GM food).<a href="#cite_note-VIC_ag-171">[171]</a><a href="#cite_note-OTRWebsite-172">[172]</a> </td> <td>The individual state governments can then assess the impact of release on markets and trade and apply further legislation to control approved genetically modified products.<a href="#cite_note-OTRWebsite-172">[172]</a> </td></tr></tbody></table> One of the key issues concerning regulators is whether GM products should be labeled. The <a href="/wiki/European_Commission" title="European Commission">European Commission</a> says that mandatory labeling and traceability are needed to allow for informed choice, avoid potential <a href="/wiki/False_advertising" title="False advertising">false advertising</a><a href="#cite_note-EC1-173">[173]</a> and facilitate the withdrawal of products if adverse effects on health or the environment are discovered.<a href="#cite_note-EC2-174">[174]</a> The <a href="/wiki/American_Medical_Association" title="American Medical Association">American Medical Association</a><a href="#cite_note-AMA-175">[175]</a> and the <a href="/wiki/American_Association_for_the_Advancement_of_Science" title="American Association for the Advancement of Science">American Association for the Advancement of Science</a><a href="#cite_note-AAAS-176">[176]</a> say that absent scientific evidence of harm even voluntary labeling is <a href="/wiki/Fear,_uncertainty_and_doubt" class="mw-redirect" title="Fear, uncertainty and doubt">misleading</a> and will falsely alarm consumers. Labeling of GMO products in the marketplace is required in 64 countries.<a href="#cite_note-Burlington-2014-177">[177]</a> Labeling can be mandatory up to a threshold GM content level (which varies between countries) or voluntary. In Canada and the US labeling of GM food is voluntary,<a href="#cite_note-RegGMFood-178">[178]</a> while in Europe all food (including <a href="/wiki/Processed_food" class="mw-redirect" title="Processed food">processed food</a>) or <a href="/wiki/Compound_feed" class="mw-redirect" title="Compound feed">feed</a> which contains greater than 0.9% of approved GMOs must be labelled.<a href="#cite_note-Davison2010-161">[161]</a> <div class="mw-heading mw-heading2"><h2 id="Controversy">Controversy</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=13" title="Edit section: Controversy">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Genetically_modified_food_controversies" title="Genetically modified food controversies">Genetically modified food controversies</a></div> Critics have objected to the use of genetic engineering on several grounds, including ethical, ecological and economic concerns. Many of these concerns involve GM crops and whether food produced from them is safe and what impact growing them will have on the environment. These controversies have led to litigation, international trade disputes, and protests, and to restrictive regulation of commercial products in some countries.<a href="#cite_note-179">[179]</a> Accusations that scientists are "<a href="/wiki/Playing_God_(ethics)" title="Playing God (ethics)">playing God</a>" and other <a href="/wiki/Religious_views_on_genetically_modified_foods" title="Religious views on genetically modified foods">religious issues</a> have been ascribed to the technology from the beginning.<a href="#cite_note-180">[180]</a> Other ethical issues raised include the <a href="/wiki/Biological_patent" title="Biological patent">patenting of life</a>,<a href="#cite_note-181">[181]</a> the use of <a href="/wiki/Intellectual_property" title="Intellectual property">intellectual property</a> rights,<a href="#cite_note-182">[182]</a> the level of labeling on products,<a href="#cite_note-183">[183]</a><a href="#cite_note-184">[184]</a> control of the food supply<a href="#cite_note-185">[185]</a> and the objectivity of the regulatory process.<a href="#cite_note-186">[186]</a> Although doubts have been raised,<a href="#cite_note-187">[187]</a> economically most studies have found growing GM crops to be beneficial to farmers.<a href="#cite_note-188">[188]</a><a href="#cite_note-189">[189]</a><a href="#cite_note-190">[190]</a> <a href="/wiki/Gene_flow" title="Gene flow">Gene flow</a> between GM crops and compatible plants, along with increased use of selective <a href="/wiki/Herbicide" title="Herbicide">herbicides</a>, can increase the risk of "<a href="/wiki/Superweeds" class="mw-redirect" title="Superweeds">superweeds</a>" developing.<a href="#cite_note-191">[191]</a> Other environmental concerns involve potential impacts on non-target organisms, including <a href="/wiki/Soil_microbes" class="mw-redirect" title="Soil microbes">soil microbes</a>,<a href="#cite_note-:1-192">[192]</a> and an increase in secondary and resistant insect pests.<a href="#cite_note-193">[193]</a><a href="#cite_note-194">[194]</a> Many of the environmental impacts regarding GM crops may take many years to be understood and are also evident in conventional agriculture practices.<a href="#cite_note-:1-192">[192]</a><a href="#cite_note-195">[195]</a> With the commercialisation of <a href="/wiki/Genetically_modified_fish" title="Genetically modified fish">genetically modified fish</a> there are concerns over what the environmental consequences will be if they escape.<a href="#cite_note-196">[196]</a> There are three main concerns over the safety of genetically modified food: whether they may provoke an <a href="/wiki/Allergic_reaction" class="mw-redirect" title="Allergic reaction">allergic reaction</a>; whether the genes could transfer from the food into human cells; and whether the genes not approved for human consumption could <a href="/wiki/Outcrossing" title="Outcrossing">outcross</a> to other crops.<a href="#cite_note-197">[197]</a> There is a <a href="/wiki/Scientific_consensus" title="Scientific consensus">scientific consensus</a><a href="#cite_note-198">[198]</a><a href="#cite_note-199">[199]</a><a href="#cite_note-200">[200]</a><a href="#cite_note-201">[201]</a> that currently available food derived from GM crops poses no greater risk to human health than conventional food,<a href="#cite_note-202">[202]</a><a href="#cite_note-203">[203]</a><a href="#cite_note-204">[204]</a><a href="#cite_note-205">[205]</a><a href="#cite_note-206">[206]</a> but that each GM food needs to be tested on a case-by-case basis before introduction.<a href="#cite_note-207">[207]</a><a href="#cite_note-208">[208]</a><a href="#cite_note-209">[209]</a> Nonetheless, members of the public are less likely than scientists to perceive GM foods as safe.<a href="#cite_note-210">[210]</a><a href="#cite_note-211">[211]</a><a href="#cite_note-212">[212]</a><a href="#cite_note-213">[213]</a> <div class="mw-heading mw-heading2"><h2 id="In_popular_culture">In popular culture</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=14" title="Edit section: In popular culture">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951"><div role="note" class="hatnote navigation-not-searchable">Main article: <a href="/wiki/Genetics_in_fiction#Genetic_engineering" title="Genetics in fiction">Genetics in fiction § Genetic engineering</a></div> Genetic engineering features in many <a href="/wiki/Science_fiction" title="Science fiction">science fiction</a> stories.<a href="#cite_note-SFE-214">[214]</a> <a href="/wiki/Frank_Herbert" title="Frank Herbert">Frank Herbert</a>'s novel <a href="/wiki/The_White_Plague" title="The White Plague">The White Plague</a> describes the deliberate use of genetic engineering to create a <a href="/wiki/Pathogen" title="Pathogen">pathogen</a> which specifically kills women.<a href="#cite_note-SFE-214">[214]</a> Another of Herbert's creations, the <a href="/wiki/Dune_(franchise)" title="Dune (franchise)">Dune</a> series of novels, uses genetic engineering to create the powerful <a href="/wiki/Tleilaxu" class="mw-redirect" title="Tleilaxu">Tleilaxu</a>.<a href="#cite_note-215">[215]</a> Few films have informed audiences about genetic engineering, with the exception of the 1978 <a href="/wiki/The_Boys_from_Brazil_(film)" title="The Boys from Brazil (film)">The Boys from Brazil</a> and the 1993 <a href="/wiki/Jurassic_Park_(film)" title="Jurassic Park (film)">Jurassic Park</a>, both of which make use of a lesson, a demonstration, and a clip of scientific film.<a href="#cite_note-Moraga2-216">[216]</a><a href="#cite_note-Wellcome-217">[217]</a> Genetic engineering methods are weakly represented in film; Michael Clark, writing for the <a href="/wiki/Wellcome_Trust" title="Wellcome Trust">Wellcome Trust</a>, calls the portrayal of genetic engineering and biotechnology "seriously distorted"<a href="#cite_note-Wellcome-217">[217]</a> in films such as <a href="/wiki/The_6th_Day" title="The 6th Day">The 6th Day</a>. In Clark's view, the biotechnology is typically "given fantastic but visually arresting forms" while the science is either relegated to the background or fictionalised to suit a young audience.<a href="#cite_note-Wellcome-217">[217]</a> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=15" title="Edit section: See also">edit</a>]</div> <ul><li><a href="/wiki/Biological_engineering" title="Biological engineering">Biological engineering</a></li> <li><a href="/wiki/Modifications_(genetics)" title="Modifications (genetics)">Modifications (genetics)</a></li> <li><a href="/wiki/Mutagenesis_(molecular_biology_technique)" title="Mutagenesis (molecular biology technique)">Mutagenesis (molecular biology technique)</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=16" title="Edit section: References">edit</a>]</div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><a href="#cite_ref-1">^</a> <style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.genome.gov/genetics-glossary/Genetic-Engineering">"Genetic Engineering"</a>. Genome.gov. Retrieved 20 February 2022.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Genome.gov&rft.atitle=Genetic+Engineering&rft_id=https%3A%2F%2Fwww.genome.gov%2Fgenetics-glossary%2FGenetic-Engineering&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-2"><a href="#cite_ref-2">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.epa.gov/OCEPAterms/gterms.html">"Terms and Acronyms"</a>. U.S. Environmental Protection Agency online. Retrieved 16 July 2015.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=U.S.+Environmental+Protection+Agency+online&rft.atitle=Terms+and+Acronyms&rft_id=http%3A%2F%2Fwww.epa.gov%2FOCEPAterms%2Fgterms.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-3"><a href="#cite_ref-3">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVertDoiHellwichHess2012" class="citation journal cs1">Vert M, Doi Y, Hellwich KH, Hess M, Hodge P, Kubisa P, Rinaudo M, Schué F (2012). <a rel="nofollow" class="external text" href="https://doi.org/10.1351%2FPAC-REC-10-12-04">"Terminology for biorelated polymers and applications (IUPAC Recommendations 2012)"</a>. <a href="/wiki/Pure_and_Applied_Chemistry" title="Pure and Applied Chemistry">Pure and Applied Chemistry</a>. 84 (2): 377–410. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1351%2FPAC-REC-10-12-04">10.1351/PAC-REC-10-12-04</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:98107080">98107080</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Pure+and+Applied+Chemistry&rft.atitle=Terminology+for+biorelated+polymers+and+applications+%28IUPAC+Recommendations+2012%29&rft.volume=84&rft.issue=2&rft.pages=377-410&rft.date=2012&rft_id=info%3Adoi%2F10.1351%2FPAC-REC-10-12-04&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A98107080%23id-name%3DS2CID&rft.aulast=Vert&rft.aufirst=M&rft.au=Doi%2C+Y&rft.au=Hellwich%2C+KH&rft.au=Hess%2C+M&rft.au=Hodge%2C+P&rft.au=Kubisa%2C+P&rft.au=Rinaudo%2C+M&rft.au=Schu%C3%A9%2C+F&rft_id=https%3A%2F%2Fdoi.org%2F10.1351%252FPAC-REC-10-12-04&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-4"><a href="#cite_ref-4">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://royalsociety.org/topics-policy/projects/gm-plants/how-does-gm-differ-from-conventional-plant-breeding/">"How does GM differ from conventional plant breeding?"</a>. royalsociety.org. Retrieved 14 November 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=royalsociety.org&rft.atitle=How+does+GM+differ+from+conventional+plant+breeding%3F&rft_id=https%3A%2F%2Froyalsociety.org%2Ftopics-policy%2Fprojects%2Fgm-plants%2Fhow-does-gm-differ-from-conventional-plant-breeding%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-5"><a href="#cite_ref-5">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFErwinGendinKleiman2015" class="citation book cs1">Erwin E, Gendin S, Kleiman L (22 December 2015). Ethical Issues in Scientific Research: An Anthology. Routledge. p. 338. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-134-81774-0" title="Special:BookSources/978-1-134-81774-0"><bdi>978-1-134-81774-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Ethical+Issues+in+Scientific+Research%3A+An+Anthology&rft.pages=338&rft.pub=Routledge&rft.date=2015-12-22&rft.isbn=978-1-134-81774-0&rft.aulast=Erwin&rft.aufirst=Edward&rft.au=Gendin%2C+Sidney&rft.au=Kleiman%2C+Lowell&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-6"><a href="#cite_ref-6">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAlexander2003" class="citation journal cs1">Alexander DR (May 2003). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1742694">"Uses and abuses of genetic engineering"</a>. Postgraduate Medical Journal. 79 (931): 249–51. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1136%2Fpmj.79.931.249">10.1136/pmj.79.931.249</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1742694">1742694</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12782769">12782769</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Postgraduate+Medical+Journal&rft.atitle=Uses+and+abuses+of+genetic+engineering&rft.volume=79&rft.issue=931&rft.pages=249-51&rft.date=2003-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1742694%23id-name%3DPMC&rft_id=info%3Apmid%2F12782769&rft_id=info%3Adoi%2F10.1136%2Fpmj.79.931.249&rft.aulast=Alexander&rft.aufirst=DR&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1742694&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-7"><a href="#cite_ref-7">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNielsen2013" class="citation journal cs1">Nielsen J (1 July 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728191">"Production of biopharmaceutical proteins by yeast: advances through metabolic engineering"</a>. Bioengineered. 4 (4): 207–11. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.4161%2Fbioe.22856">10.4161/bioe.22856</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728191">3728191</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23147168">23147168</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Bioengineered&rft.atitle=Production+of+biopharmaceutical+proteins+by+yeast%3A+advances+through+metabolic+engineering&rft.volume=4&rft.issue=4&rft.pages=207-11&rft.date=2013-07-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3728191%23id-name%3DPMC&rft_id=info%3Apmid%2F23147168&rft_id=info%3Adoi%2F10.4161%2Fbioe.22856&rft.aulast=Nielsen&rft.aufirst=J&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3728191&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-8"><a href="#cite_ref-8">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFQaimKouser2013" class="citation journal cs1">Qaim M, Kouser S (5 June 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674000">"Genetically modified crops and food security"</a>. PLOS ONE. 8 (6): e64879. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2013PLoSO...864879Q">2013PLoSO...864879Q</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.pone.0064879">10.1371/journal.pone.0064879</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674000">3674000</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23755155">23755155</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLOS+ONE&rft.atitle=Genetically+modified+crops+and+food+security&rft.volume=8&rft.issue=6&rft.pages=e64879&rft.date=2013-06-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3674000%23id-name%3DPMC&rft_id=info%3Apmid%2F23755155&rft_id=info%3Adoi%2F10.1371%2Fjournal.pone.0064879&rft_id=info%3Abibcode%2F2013PLoSO...864879Q&rft.aulast=Qaim&rft.aufirst=M&rft.au=Kouser%2C+S&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3674000&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-EU17-9">^ <a href="#cite_ref-EU17_9-0">a</a> <a href="#cite_ref-EU17_9-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFThe_European_Parliament_and_the_council_of_the_European_Union2001" class="citation magazine cs1">The European Parliament and the council of the European Union (12 March 2001). <a rel="nofollow" class="external text" href="https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A32001L0018">"Directive on the release of genetically modified organisms (GMOs) Directive 2001/18/EC ANNEX I A"</a>. Official Journal of the European Communities.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Official+Journal+of+the+European+Communities&rft.atitle=Directive+on+the+release+of+genetically+modified+organisms+%28GMOs%29+Directive+2001%2F18%2FEC+ANNEX+I+A&rft.date=2001-03-12&rft.au=The+European+Parliament+and+the+council+of+the+European+Union&rft_id=https%3A%2F%2Feur-lex.europa.eu%2Flegal-content%2FEN%2FTXT%2F%3Furi%3Dcelex%253A32001L0018&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:2-10"><a href="#cite_ref-:2_10-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20130514202621/http://ec.europa.eu/agriculture/publi/gmo/gmo.pdf">"Economic Impacts of Genetically Modified Crops on the Agri-Food Sector; p. 42 Glossary – Term and Definitions"</a> (PDF). The European Commission Directorate-General for Agriculture. Archived from <a rel="nofollow" class="external text" href="http://ec.europa.eu/agriculture/publi/gmo/gmo.pdf">the original</a> (PDF) on 14 May 2013. <q>Genetic engineering: The manipulation of an organism's genetic endowment by introducing or eliminating specific genes through modern molecular biology techniques. A broad definition of genetic engineering also includes selective breeding and other means of artificial selection</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=The+European+Commission+Directorate-General+for+Agriculture&rft.atitle=Economic+Impacts+of+Genetically+Modified+Crops+on+the+Agri-Food+Sector%3B+p.+42+Glossary+%E2%80%93+Term+and+Definitions&rft_id=http%3A%2F%2Fec.europa.eu%2Fagriculture%2Fpubli%2Fgmo%2Fgmo.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-11"><a href="#cite_ref-11">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVan_Eenennaam" class="citation web cs1">Van Eenennaam A. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110511121055/http://agribiotech.info/details/Alison%20-%20cloning%20March%208%20-%2003.pdf">"Is Livestock Cloning Another Form of Genetic Engineering?"</a> (PDF). agbiotech. Archived from <a rel="nofollow" class="external text" href="http://agribiotech.info/details/Alison%20-%20cloning%20March%208%20-%2003.pdf">the original</a> (PDF) on 11 May 2011.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Is+Livestock+Cloning+Another+Form+of+Genetic+Engineering%3F&rft.pub=agbiotech&rft.aulast=Van+Eenennaam&rft.aufirst=Alison&rft_id=http%3A%2F%2Fagribiotech.info%2Fdetails%2FAlison%2520-%2520cloning%2520March%25208%2520-%252003.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-12"><a href="#cite_ref-12">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSuterDubois-DauphinKrause2006" class="citation journal cs1">Suter DM, Dubois-Dauphin M, Krause KH (July 2006). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110707003215/http://www.smw.ch/docs/pdf200x/2006/27/smw-11406.PDF">"Genetic engineering of embryonic stem cells"</a> (PDF). <a href="/wiki/Swiss_Medical_Weekly" title="Swiss Medical Weekly">Swiss Medical Weekly</a>. 136 (27–28): 413–5. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.4414%2Fsmw.2006.11406">10.4414/smw.2006.11406</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16897894">16897894</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:4945176">4945176</a>. Archived from <a rel="nofollow" class="external text" href="http://www.smw.ch/docs/pdf200x/2006/27/smw-11406.PDF">the original</a> (PDF) on 7 July 2011.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Swiss+Medical+Weekly&rft.atitle=Genetic+engineering+of+embryonic+stem+cells&rft.volume=136&rft.issue=27%E2%80%9328&rft.pages=413-5&rft.date=2006-07&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A4945176%23id-name%3DS2CID&rft_id=info%3Apmid%2F16897894&rft_id=info%3Adoi%2F10.4414%2Fsmw.2006.11406&rft.aulast=Suter&rft.aufirst=DM&rft.au=Dubois-Dauphin%2C+M&rft.au=Krause%2C+KH&rft_id=http%3A%2F%2Fwww.smw.ch%2Fdocs%2Fpdf200x%2F2006%2F27%2Fsmw-11406.PDF&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-13"><a href="#cite_ref-13">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAndrianantoandroBasuKarigWeiss2006" class="citation journal cs1">Andrianantoandro E, Basu S, Karig DK, Weiss R (16 May 2006). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681505">"Synthetic biology: new engineering rules for an emerging discipline"</a>. Molecular Systems Biology. 2 (2006.0028): 2006.0028. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fmsb4100073">10.1038/msb4100073</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1681505">1681505</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16738572">16738572</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Molecular+Systems+Biology&rft.atitle=Synthetic+biology%3A+new+engineering+rules+for+an+emerging+discipline&rft.volume=2&rft.issue=2006.0028&rft.pages=2006.0028&rft.date=2006-05-16&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1681505%23id-name%3DPMC&rft_id=info%3Apmid%2F16738572&rft_id=info%3Adoi%2F10.1038%2Fmsb4100073&rft.aulast=Andrianantoandro&rft.aufirst=E&rft.au=Basu%2C+S&rft.au=Karig%2C+DK&rft.au=Weiss%2C+R&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1681505&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-14"><a href="#cite_ref-14">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.csiro.au/Outcomes/Food-and-Agriculture/WhatIsGM.aspx">"What is genetic modification (GM)?"</a>. <a href="/wiki/CSIRO" title="CSIRO">CSIRO</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=What+is+genetic+modification+%28GM%29%3F&rft.pub=CSIRO&rft_id=http%3A%2F%2Fwww.csiro.au%2FOutcomes%2FFood-and-Agriculture%2FWhatIsGM.aspx&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-15"><a href="#cite_ref-15">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJacobsenSchouten2008" class="citation journal cs1">Jacobsen E, Schouten HJ (2008). <a rel="nofollow" class="external text" href="http://library.wur.nl/WebQuery/wurpubs/fulltext/44813">"Cisgenesis, a New Tool for Traditional Plant Breeding, Should be Exempted from the Regulation on Genetically Modified Organisms in a Step by Step Approach"</a>. Potato Research. 51: 75–88. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs11540-008-9097-y">10.1007/s11540-008-9097-y</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:38742532">38742532</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Potato+Research&rft.atitle=Cisgenesis%2C+a+New+Tool+for+Traditional+Plant+Breeding%2C+Should+be+Exempted+from+the+Regulation+on+Genetically+Modified+Organisms+in+a+Step+by+Step+Approach&rft.volume=51&rft.pages=75-88&rft.date=2008&rft_id=info%3Adoi%2F10.1007%2Fs11540-008-9097-y&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A38742532%23id-name%3DS2CID&rft.aulast=Jacobsen&rft.aufirst=E&rft.au=Schouten%2C+HJ&rft_id=http%3A%2F%2Flibrary.wur.nl%2FWebQuery%2Fwurpubs%2Ffulltext%2F44813&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-16"><a href="#cite_ref-16">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCapecchi2001" class="citation journal cs1">Capecchi MR (October 2001). "Generating mice with targeted mutations". Nature Medicine. 7 (10): 1086–90. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnm1001-1086">10.1038/nm1001-1086</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11590420">11590420</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:14710881">14710881</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+Medicine&rft.atitle=Generating+mice+with+targeted+mutations&rft.volume=7&rft.issue=10&rft.pages=1086-90&rft.date=2001-10&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A14710881%23id-name%3DS2CID&rft_id=info%3Apmid%2F11590420&rft_id=info%3Adoi%2F10.1038%2Fnm1001-1086&rft.aulast=Capecchi&rft.aufirst=MR&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-17"><a href="#cite_ref-17">^</a> Staff <a rel="nofollow" class="external text" href="https://www.usda.gov/wps/portal/usda/usdahome?contentid=BiotechnologyGlosary.xml&navid=">Biotechnology – Glossary of Agricultural Biotechnology Terms</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20140830102928/http://www.usda.gov/wps/portal/usda/usdahome?contentid=BiotechnologyGlosary.xml&navid=">Archived</a> 30 August 2014 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> United States Department of Agriculture, "Genetic modification: The production of heritable improvements in plants or animals for specific uses, via either genetic engineering or other more traditional methods. Some countries other than the United States use this term to refer specifically to genetic engineering.", Retrieved 5 November 2012 </li> <li id="cite_note-18"><a href="#cite_ref-18">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMaryanski1999" class="citation web cs1">Maryanski JH (19 October 1999). <a rel="nofollow" class="external text" href="https://www.fda.gov/NewsEvents/Testimony/ucm115032.htm">"Genetically Engineered Foods"</a>. Center for Food Safety and Applied Nutrition at the <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">Food and Drug Administration</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Genetically+Engineered+Foods&rft.pub=Center+for+Food+Safety+and+Applied+Nutrition+at+the+Food+and+Drug+Administration&rft.date=1999-10-19&rft.aulast=Maryanski&rft.aufirst=James+H.&rft_id=https%3A%2F%2Fwww.fda.gov%2FNewsEvents%2FTestimony%2Fucm115032.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-19"><a href="#cite_ref-19">^</a> Staff (28 November 2005) <a rel="nofollow" class="external text" href="http://www.hc-sc.gc.ca/sr-sr/pubs/biotech/reg_gen_mod-eng.php">Health Canada – The Regulation of Genetically Modified Food</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20170610170104/http://www.hc-sc.gc.ca/sr-sr/pubs/biotech/reg_gen_mod-eng.php">Archived</a> 10 June 2017 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> Glossary definition of Genetically Modified: "An organism, such as a plant, animal or bacterium, is considered genetically modified if its genetic material has been altered through any method, including conventional breeding. A 'GMO' is a genetically modified organism.", Retrieved 5 November 2012 </li> <li id="cite_note-Root-20"><a href="#cite_ref-Root_20-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRoot2007" class="citation book cs1">Root C (2007). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=WGDYHvOHwmwC">Domestication</a>. Greenwood Publishing Groups.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Domestication&rft.pub=Greenwood+Publishing+Groups&rft.date=2007&rft.aulast=Root&rft.aufirst=Clive&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DWGDYHvOHwmwC&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Zohary-21"><a href="#cite_ref-Zohary_21-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFZoharyHopfWeiss2012" class="citation book cs1">Zohary D, Hopf M, Weiss E (2012). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=tc6vr0qzk_4C">Domestication of Plants in the Old World: The origin and spread of plants in the old world</a>. Oxford University Press.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Domestication+of+Plants+in+the+Old+World%3A+The+origin+and+spread+of+plants+in+the+old+world&rft.pub=Oxford+University+Press&rft.date=2012&rft.aulast=Zohary&rft.aufirst=Daniel&rft.au=Hopf%2C+Maria&rft.au=Weiss%2C+Ehud&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Dtc6vr0qzk_4C&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-22"><a href="#cite_ref-22">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTimofeev-Ressovsky1934" class="citation journal cs1">Timofeev-Ressovsky NW (October 1934). <a rel="nofollow" class="external text" href="https://archive.org/details/in.ernet.dli.2015.26044/page/n449">"The Experimental Production of Mutations"</a>. Biological Reviews. 9 (4): 411–457. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1469-185X.1934.tb01255.x">10.1111/j.1469-185X.1934.tb01255.x</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:86396986">86396986</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biological+Reviews&rft.atitle=The+Experimental+Production+of+Mutations&rft.volume=9&rft.issue=4&rft.pages=411-457&rft.date=1934-10&rft_id=info%3Adoi%2F10.1111%2Fj.1469-185X.1934.tb01255.x&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A86396986%23id-name%3DS2CID&rft.aulast=Timofeev-Ressovsky&rft.aufirst=NW&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fin.ernet.dli.2015.26044%2Fpage%2Fn449&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-23"><a href="#cite_ref-23">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFStableford2004" class="citation book cs1">Stableford BM (2004). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=nzmIPZg5xicC&pg=PA9">Historical dictionary of science fiction literature</a>. Scarecrow Press. p. 133. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-8108-4938-9" title="Special:BookSources/978-0-8108-4938-9"><bdi>978-0-8108-4938-9</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Historical+dictionary+of+science+fiction+literature&rft.pages=133&rft.pub=Scarecrow+Press&rft.date=2004&rft.isbn=978-0-8108-4938-9&rft.aulast=Stableford&rft.aufirst=Brian+M.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DnzmIPZg5xicC%26pg%3DPA9&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-24"><a href="#cite_ref-24">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHersheyChase1952" class="citation journal cs1">Hershey AD, Chase M (May 1952). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147348">"Independent functions of viral protein and nucleic acid in growth of bacteriophage"</a>. The Journal of General Physiology. 36 (1): 39–56. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1085%2Fjgp.36.1.39">10.1085/jgp.36.1.39</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147348">2147348</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12981234">12981234</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+General+Physiology&rft.atitle=Independent+functions+of+viral+protein+and+nucleic+acid+in+growth+of+bacteriophage&rft.volume=36&rft.issue=1&rft.pages=39-56&rft.date=1952-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2147348%23id-name%3DPMC&rft_id=info%3Apmid%2F12981234&rft_id=info%3Adoi%2F10.1085%2Fjgp.36.1.39&rft.aulast=Hershey&rft.aufirst=AD&rft.au=Chase%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2147348&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-25"><a href="#cite_ref-25">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation encyclopaedia cs1"><a rel="nofollow" class="external text" href="http://www.sf-encyclopedia.com/entry/genetic_engineering">"Genetic Engineering"</a>. Encyclopedia of Science Fiction. 2 April 2015.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Genetic+Engineering&rft.btitle=Encyclopedia+of+Science+Fiction&rft.date=2015-04-02&rft_id=http%3A%2F%2Fwww.sf-encyclopedia.com%2Fentry%2Fgenetic_engineering&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-26"><a href="#cite_ref-26">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFShiv_Kant_PrasadAjay_Dash2008" class="citation book cs1">Shiv Kant Prasad; Ajay Dash (2008). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=WJrvj0pOJx0C&pg=PA164">Modern Concepts in Nanotechnology, Volume 5</a>. Discovery Publishing House. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-81-8356-296-6" title="Special:BookSources/978-81-8356-296-6"><bdi>978-81-8356-296-6</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Modern+Concepts+in+Nanotechnology%2C+Volume+5&rft.pub=Discovery+Publishing+House&rft.date=2008&rft.isbn=978-81-8356-296-6&rft.au=Shiv+Kant+Prasad&rft.au=Ajay+Dash&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DWJrvj0pOJx0C%26pg%3DPA164&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-27"><a href="#cite_ref-27">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJacksonSymonsBerg1972" class="citation journal cs1">Jackson DA, Symons RH, Berg P (October 1972). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC389671">"Biochemical method for inserting new genetic information into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli"</a>. Proceedings of the National Academy of Sciences of the United States of America. 69 (10): 2904–9. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1972PNAS...69.2904J">1972PNAS...69.2904J</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.69.10.2904">10.1073/pnas.69.10.2904</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC389671">389671</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/4342968">4342968</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Biochemical+method+for+inserting+new+genetic+information+into+DNA+of+Simian+Virus+40%3A+circular+SV40+DNA+molecules+containing+lambda+phage+genes+and+the+galactose+operon+of+Escherichia+coli&rft.volume=69&rft.issue=10&rft.pages=2904-9&rft.date=1972-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC389671%23id-name%3DPMC&rft_id=info%3Apmid%2F4342968&rft_id=info%3Adoi%2F10.1073%2Fpnas.69.10.2904&rft_id=info%3Abibcode%2F1972PNAS...69.2904J&rft.aulast=Jackson&rft.aufirst=DA&rft.au=Symons%2C+RH&rft.au=Berg%2C+P&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC389671&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-28"><a href="#cite_ref-28">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFArnold2009" class="citation web cs1">Arnold P (2009). <a rel="nofollow" class="external text" href="http://www.brighthub.com/science/genetics/articles/21983.aspx">"History of Genetics: Genetic Engineering Timeline"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=History+of+Genetics%3A+Genetic+Engineering+Timeline&rft.date=2009&rft.aulast=Arnold&rft.aufirst=Paul&rft_id=http%3A%2F%2Fwww.brighthub.com%2Fscience%2Fgenetics%2Farticles%2F21983.aspx&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-29"><a href="#cite_ref-29">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGutschiHermannStenzlTscheliessnigg1973" class="citation journal cs1">Gutschi S, Hermann W, Stenzl W, Tscheliessnigg KH (1 May 1973). "[Displacement of electrodes in pacemaker patients (author's transl)]". Zentralblatt für Chirurgie. 104 (2): 100–4. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/433482">433482</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Zentralblatt+f%C3%BCr+Chirurgie&rft.atitle=%5BDisplacement+of+electrodes+in+pacemaker+patients+%28author%27s+transl%29%5D&rft.volume=104&rft.issue=2&rft.pages=100-4&rft.date=1973-05-01&rft_id=info%3Apmid%2F433482&rft.aulast=Gutschi&rft.aufirst=S&rft.au=Hermann%2C+W&rft.au=Stenzl%2C+W&rft.au=Tscheliessnigg%2C+KH&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-pmid4364530-30"><a href="#cite_ref-pmid4364530_30-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJaenischMintz1974" class="citation journal cs1">Jaenisch R, Mintz B (April 1974). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC388203">"Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA"</a>. Proceedings of the National Academy of Sciences of the United States of America. 71 (4): 1250–4. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1974PNAS...71.1250J">1974PNAS...71.1250J</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.71.4.1250">10.1073/pnas.71.4.1250</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC388203">388203</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/4364530">4364530</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Simian+virus+40+DNA+sequences+in+DNA+of+healthy+adult+mice+derived+from+preimplantation+blastocysts+injected+with+viral+DNA&rft.volume=71&rft.issue=4&rft.pages=1250-4&rft.date=1974-04&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC388203%23id-name%3DPMC&rft_id=info%3Apmid%2F4364530&rft_id=info%3Adoi%2F10.1073%2Fpnas.71.4.1250&rft_id=info%3Abibcode%2F1974PNAS...71.1250J&rft.aulast=Jaenisch&rft.aufirst=R&rft.au=Mintz%2C+B&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC388203&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-ReferenceA-31">^ <a href="#cite_ref-ReferenceA_31-0">a</a> <a href="#cite_ref-ReferenceA_31-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBergBaltimoreBrennerRoblin1975" class="citation journal cs1">Berg P, Baltimore D, Brenner S, Roblin RO, Singer MF (June 1975). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC432675">"Summary statement of the Asilomar conference on recombinant DNA molecules"</a>. Proceedings of the National Academy of Sciences of the United States of America. 72 (6): 1981–4. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1975PNAS...72.1981B">1975PNAS...72.1981B</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.72.6.1981">10.1073/pnas.72.6.1981</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC432675">432675</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/806076">806076</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Summary+statement+of+the+Asilomar+conference+on+recombinant+DNA+molecules&rft.volume=72&rft.issue=6&rft.pages=1981-4&rft.date=1975-06&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC432675%23id-name%3DPMC&rft_id=info%3Apmid%2F806076&rft_id=info%3Adoi%2F10.1073%2Fpnas.72.6.1981&rft_id=info%3Abibcode%2F1975PNAS...72.1981B&rft.aulast=Berg&rft.aufirst=P&rft.au=Baltimore%2C+D&rft.au=Brenner%2C+S&rft.au=Roblin%2C+RO&rft.au=Singer%2C+MF&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC432675&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-32"><a href="#cite_ref-32">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20120910070047/http://oba.od.nih.gov/rdna/nih_guidelines_oba.html">"NIH Guidelines for research involving recombinant DNA molecules"</a>. Office of Biotechnology Activities. U.S. Department of Health and Human Services. Archived from <a rel="nofollow" class="external text" href="http://oba.od.nih.gov/rdna/nih_guidelines_oba.html">the original</a> on 10 September 2012.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Office+of+Biotechnology+Activities&rft.atitle=NIH+Guidelines+for+research+involving+recombinant+DNA+molecules&rft_id=http%3A%2F%2Foba.od.nih.gov%2Frdna%2Fnih_guidelines_oba.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:0-33">^ <a href="#cite_ref-:0_33-0">a</a> <a href="#cite_ref-:0_33-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGoeddelKleidBolivarHeyneker1979" class="citation journal cs1">Goeddel DV, Kleid DG, Bolivar F, Heyneker HL, Yansura DG, Crea R, Hirose T, Kraszewski A, Itakura K, Riggs AD (January 1979). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC382885">"Expression in Escherichia coli of chemically synthesized genes for human insulin"</a>. Proceedings of the National Academy of Sciences of the United States of America. 76 (1): 106–10. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1979PNAS...76..106G">1979PNAS...76..106G</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.76.1.106">10.1073/pnas.76.1.106</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC382885">382885</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/85300">85300</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Expression+in+Escherichia+coli+of+chemically+synthesized+genes+for+human+insulin&rft.volume=76&rft.issue=1&rft.pages=106-10&rft.date=1979-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC382885%23id-name%3DPMC&rft_id=info%3Apmid%2F85300&rft_id=info%3Adoi%2F10.1073%2Fpnas.76.1.106&rft_id=info%3Abibcode%2F1979PNAS...76..106G&rft.aulast=Goeddel&rft.aufirst=DV&rft.au=Kleid%2C+DG&rft.au=Bolivar%2C+F&rft.au=Heyneker%2C+HL&rft.au=Yansura%2C+DG&rft.au=Crea%2C+R&rft.au=Hirose%2C+T&rft.au=Kraszewski%2C+A&rft.au=Itakura%2C+K&rft.au=Riggs%2C+AD&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC382885&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-34"><a href="#cite_ref-34">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFUS_Supreme_Court_Cases_from_Justia_&_Oyez1980" class="citation web cs1">US Supreme Court Cases from Justia & Oyez (16 June 1980). <a rel="nofollow" class="external text" href="http://supreme.justia.com/us/447/303/case.html">"Diamond V Chakrabarty"</a>. Justia. Retrieved 17 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Justia&rft.atitle=Diamond+V+Chakrabarty&rft.date=1980-06-16&rft.au=US+Supreme+Court+Cases+from+Justia+%26+Oyez&rft_id=http%3A%2F%2Fsupreme.justia.com%2Fus%2F447%2F303%2Fcase.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-35"><a href="#cite_ref-35">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation magazine cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20111027011602/http://www.time.com/time/magazine/article/0,9171,949646-1,00.html">"Artificial Genes"</a>. <a href="/wiki/Time_(magazine)" title="Time (magazine)">Time</a>. 15 November 1982. Archived from <a rel="nofollow" class="external text" href="http://www.time.com/time/magazine/article/0,9171,949646-1,00.html">the original</a> on 27 October 2011. Retrieved 17 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Time&rft.atitle=Artificial+Genes&rft.date=1982-11-15&rft_id=http%3A%2F%2Fwww.time.com%2Ftime%2Fmagazine%2Farticle%2F0%2C9171%2C949646-1%2C00.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-36"><a href="#cite_ref-36">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBratspies2007" class="citation journal cs1">Bratspies R (2007). "Some Thoughts on the American Approach to Regulating Genetically Modified Organisms". Kansas Journal of Law & Public Policy. 16 (3): 101–31. <a href="/wiki/SSRN_(identifier)" class="mw-redirect" title="SSRN (identifier)">SSRN</a> <a rel="nofollow" class="external text" href="https://papers.ssrn.com/sol3/papers.cfm?abstract_id=1017832">1017832</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Kansas+Journal+of+Law+%26+Public+Policy&rft.atitle=Some+Thoughts+on+the+American+Approach+to+Regulating+Genetically+Modified+Organisms&rft.volume=16&rft.issue=3&rft.pages=101-31&rft.date=2007&rft_id=https%3A%2F%2Fpapers.ssrn.com%2Fsol3%2Fpapers.cfm%3Fabstract_id%3D1017832%23id-name%3DSSRN&rft.aulast=Bratspies&rft.aufirst=Rebecca&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-BBC2002-37">^ <a href="#cite_ref-BBC2002_37-0">a</a> <a href="#cite_ref-BBC2002_37-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="http://news.bbc.co.uk/2/hi/science/nature/2045286.stm">"GM crops: A bitter harvest?"</a>. 14 June 2002. Retrieved 30 March 2023.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=GM+crops%3A+A+bitter+harvest%3F&rft.date=2002-06-14&rft_id=http%3A%2F%2Fnews.bbc.co.uk%2F2%2Fhi%2Fscience%2Fnature%2F2045286.stm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-38"><a href="#cite_ref-38">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMaugh1987" class="citation news cs1">Maugh, Thomas H. II (9 June 1987). <a rel="nofollow" class="external text" href="https://www.latimes.com/archives/la-xpm-1987-06-09-mn-6024-story.html">"Altered Bacterium Does Its Job: Frost Failed to Damage Sprayed Test Crop, Company Says"</a>. <a href="/wiki/Los_Angeles_Times" title="Los Angeles Times">Los Angeles Times</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Los+Angeles+Times&rft.atitle=Altered+Bacterium+Does+Its+Job%3A+Frost+Failed+to+Damage+Sprayed+Test+Crop%2C+Company+Says&rft.date=1987-06-09&rft.aulast=Maugh&rft.aufirst=Thomas+H.+II&rft_id=https%3A%2F%2Fwww.latimes.com%2Farchives%2Fla-xpm-1987-06-09-mn-6024-story.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-39"><a href="#cite_ref-39">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJames1996" class="citation web cs1">James C (1996). <a rel="nofollow" class="external text" href="http://www.isaaa.org/kc/Publications/pdfs/isaaabriefs/Briefs%201.pdf">"Global Review of the Field Testing and Commercialization of Transgenic Plants: 1986 to 1995"</a> (PDF). The International Service for the Acquisition of Agri-biotech Applications. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20100616175626/http://isaaa.org/kc/Publications/pdfs/isaaabriefs/Briefs%201.pdf">Archived</a> (PDF) from the original on 16 June 2010. Retrieved 17 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Global+Review+of+the+Field+Testing+and+Commercialization+of+Transgenic+Plants%3A+1986+to+1995&rft.pub=The+International+Service+for+the+Acquisition+of+Agri-biotech+Applications&rft.date=1996&rft.aulast=James&rft.aufirst=Clive&rft_id=http%3A%2F%2Fwww.isaaa.org%2Fkc%2FPublications%2Fpdfs%2Fisaaabriefs%2FBriefs%25201.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-James1997-40"><a href="#cite_ref-James1997_40-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJames1997" class="citation journal cs1">James C (1997). <a rel="nofollow" class="external text" href="http://www.isaaa.org/resources/publications/briefs/05/download/isaaa-brief-05-1997.pdf">"Global Status of Transgenic Crops in 1997"</a> (PDF). ISAAA Briefs No. 5.: 31. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20090116155014/http://www.isaaa.org/Resources/Publications/briefs/05/download/isaaa-brief-05-1997.pdf">Archived</a> (PDF) from the original on 16 January 2009.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=ISAAA+Briefs+No.+5.&rft.atitle=Global+Status+of+Transgenic+Crops+in+1997&rft.pages=31&rft.date=1997&rft.aulast=James&rft.aufirst=Clive&rft_id=http%3A%2F%2Fwww.isaaa.org%2Fresources%2Fpublications%2Fbriefs%2F05%2Fdownload%2Fisaaa-brief-05-1997.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-41"><a href="#cite_ref-41">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBrueningLyons2000" class="citation journal cs1">Bruening G, Lyons JM (2000). "The case of the FLAVR SAVR tomato". California Agriculture. 54 (4): 6–7. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3733%2Fca.v054n04p6">10.3733/ca.v054n04p6</a> (inactive 1 November 2024).</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=California+Agriculture&rft.atitle=The+case+of+the+FLAVR+SAVR+tomato&rft.volume=54&rft.issue=4&rft.pages=6-7&rft.date=2000&rft_id=info%3Adoi%2F10.3733%2Fca.v054n04p6&rft.aulast=Bruening&rft.aufirst=G&rft.au=Lyons%2C+JM&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: DOI inactive as of November 2024 (<a href="/wiki/Category:CS1_maint:_DOI_inactive_as_of_November_2024" title="Category:CS1 maint: DOI inactive as of November 2024">link</a>) </li> <li id="cite_note-42"><a href="#cite_ref-42">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMacKenzie1994" class="citation magazine cs1">MacKenzie D (18 June 1994). <a rel="nofollow" class="external text" href="https://www.newscientist.com/article/mg14219301.100-transgenic-tobacco-is-european-first.html">"Transgenic tobacco is European first"</a>. <a href="/wiki/New_Scientist" title="New Scientist">New Scientist</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=New+Scientist&rft.atitle=Transgenic+tobacco+is+European+first&rft.date=1994-06-18&rft.aulast=MacKenzie&rft.aufirst=Debora&rft_id=https%3A%2F%2Fwww.newscientist.com%2Farticle%2Fmg14219301.100-transgenic-tobacco-is-european-first.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-43"><a href="#cite_ref-43">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://news.google.com/newspapers?nid=2199&dat=19950506&id=A0YyAAAAIBAJ&sjid=jOYFAAAAIBAJ&pg=4631,1776980&hl=en">"Lawrence Journal-World - Google News Archive Search"</a>. news.google.com. Retrieved 30 March 2023.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=news.google.com&rft.atitle=Lawrence+Journal-World+-+Google+News+Archive+Search&rft_id=https%3A%2F%2Fnews.google.com%2Fnewspapers%3Fnid%3D2199%26dat%3D19950506%26id%3DA0YyAAAAIBAJ%26sjid%3DjOYFAAAAIBAJ%26pg%3D4631%2C1776980%26hl%3Den&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-44"><a href="#cite_ref-44">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.isaaa.org/resources/publications/briefs/41/executivesummary/default.asp">"Executive Summary: Global Status of Commercialized Biotech/GM Crops: 2009 - ISAAA Brief 41-2009 | ISAAA.org"</a>. www.isaaa.org. Retrieved 30 March 2023.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.isaaa.org&rft.atitle=Executive+Summary%3A+Global+Status+of+Commercialized+Biotech%2FGM+Crops%3A+2009+-+ISAAA+Brief+41-2009+%26%23124%3B+ISAAA.org&rft_id=https%3A%2F%2Fwww.isaaa.org%2Fresources%2Fpublications%2Fbriefs%2F41%2Fexecutivesummary%2Fdefault.asp&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-45"><a href="#cite_ref-45">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPennisi2010" class="citation journal cs1"><a href="/wiki/Elizabeth_Pennisi" title="Elizabeth Pennisi">Pennisi E</a> (May 2010). <a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.328.5981.958">"Genomics. Synthetic genome brings new life to bacterium"</a>. Science. 328 (5981): 958–9. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.328.5981.958">10.1126/science.328.5981.958</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20488994">20488994</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science&rft.atitle=Genomics.+Synthetic+genome+brings+new+life+to+bacterium&rft.volume=328&rft.issue=5981&rft.pages=958-9&rft.date=2010-05&rft_id=info%3Adoi%2F10.1126%2Fscience.328.5981.958&rft_id=info%3Apmid%2F20488994&rft.aulast=Pennisi&rft.aufirst=E&rft_id=https%3A%2F%2Fdoi.org%2F10.1126%252Fscience.328.5981.958&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-46"><a href="#cite_ref-46">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGibsonGlassLartigueNoskov2010" class="citation journal cs1">Gibson DG, Glass JI, Lartigue C, Noskov VN, Chuang RY, Algire MA, et al. (July 2010). "Creation of a bacterial cell controlled by a chemically synthesized genome". Science. 329 (5987): 52–6. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2010Sci...329...52G">2010Sci...329...52G</a>. <a href="/wiki/CiteSeerX_(identifier)" class="mw-redirect" title="CiteSeerX (identifier)">CiteSeerX</a> <a rel="nofollow" class="external text" href="https://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.167.1455">10.1.1.167.1455</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.1190719">10.1126/science.1190719</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20488990">20488990</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:7320517">7320517</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science&rft.atitle=Creation+of+a+bacterial+cell+controlled+by+a+chemically+synthesized+genome&rft.volume=329&rft.issue=5987&rft.pages=52-6&rft.date=2010-07&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A7320517%23id-name%3DS2CID&rft_id=info%3Abibcode%2F2010Sci...329...52G&rft_id=https%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fsummary%3Fdoi%3D10.1.1.167.1455%23id-name%3DCiteSeerX&rft_id=info%3Apmid%2F20488990&rft_id=info%3Adoi%2F10.1126%2Fscience.1190719&rft.aulast=Gibson&rft.aufirst=DG&rft.au=Glass%2C+JI&rft.au=Lartigue%2C+C&rft.au=Noskov%2C+VN&rft.au=Chuang%2C+RY&rft.au=Algire%2C+MA&rft.au=Benders%2C+GA&rft.au=Montague%2C+MG&rft.au=Ma%2C+L&rft.au=Moodie%2C+MM&rft.au=Merryman%2C+C&rft.au=Vashee%2C+S&rft.au=Krishnakumar%2C+R&rft.au=Assad-Garcia%2C+N&rft.au=Andrews-Pfannkoch%2C+C&rft.au=Denisova%2C+EA&rft.au=Young%2C+L&rft.au=Qi%2C+ZQ&rft.au=Segall-Shapiro%2C+TH&rft.au=Calvey%2C+CH&rft.au=Parmar%2C+PP&rft.au=Hutchison%2C+CA&rft.au=Smith%2C+HO&rft.au=Venter%2C+JC&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-47"><a href="#cite_ref-47">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMalyshevDhamiLavergneChen2014" class="citation journal cs1">Malyshev DA, Dhami K, Lavergne T, Chen T, Dai N, Foster JM, Corrêa IR, Romesberg FE (May 2014). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058825">"A semi-synthetic organism with an expanded genetic alphabet"</a>. Nature. 509 (7500): 385–8. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2014Natur.509..385M">2014Natur.509..385M</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnature13314">10.1038/nature13314</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058825">4058825</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24805238">24805238</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=A+semi-synthetic+organism+with+an+expanded+genetic+alphabet&rft.volume=509&rft.issue=7500&rft.pages=385-8&rft.date=2014-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4058825%23id-name%3DPMC&rft_id=info%3Apmid%2F24805238&rft_id=info%3Adoi%2F10.1038%2Fnature13314&rft_id=info%3Abibcode%2F2014Natur.509..385M&rft.aulast=Malyshev&rft.aufirst=DA&rft.au=Dhami%2C+K&rft.au=Lavergne%2C+T&rft.au=Chen%2C+T&rft.au=Dai%2C+N&rft.au=Foster%2C+JM&rft.au=Corr%C3%AAa%2C+IR&rft.au=Romesberg%2C+FE&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4058825&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-48"><a href="#cite_ref-48">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFThyerEllefson2014" class="citation journal cs1">Thyer R, Ellefson J (May 2014). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnature13335">"Synthetic biology: New letters for life's alphabet"</a>. Nature. 509 (7500): 291–2. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2014Natur.509..291T">2014Natur.509..291T</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnature13335">10.1038/nature13335</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24805244">24805244</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:4399670">4399670</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Synthetic+biology%3A+New+letters+for+life%27s+alphabet&rft.volume=509&rft.issue=7500&rft.pages=291-2&rft.date=2014-05&rft_id=info%3Adoi%2F10.1038%2Fnature13335&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A4399670%23id-name%3DS2CID&rft_id=info%3Apmid%2F24805244&rft_id=info%3Abibcode%2F2014Natur.509..291T&rft.aulast=Thyer&rft.aufirst=R&rft.au=Ellefson%2C+J&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252Fnature13335&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-49"><a href="#cite_ref-49">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPollack2015" class="citation news cs1">Pollack A (11 May 2015). <a rel="nofollow" class="external text" href="https://www.nytimes.com/2015/05/12/science/jennifer-doudna-crispr-cas9-genetic-engineering.html">"Jennifer Doudna, a Pioneer Who Helped Simplify Genome Editing"</a>. <a href="/wiki/The_New_York_Times" title="The New York Times">The New York Times</a>. <a rel="nofollow" class="external text" href="https://ghostarchive.org/archive/20220102/https://www.nytimes.com/2015/05/12/science/jennifer-doudna-crispr-cas9-genetic-engineering.html">Archived</a> from the original on 2 January 2022. Retrieved 15 November 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+York+Times&rft.atitle=Jennifer+Doudna%2C+a+Pioneer+Who+Helped+Simplify+Genome+Editing&rft.date=2015-05-11&rft.aulast=Pollack&rft.aufirst=Andrew&rft_id=https%3A%2F%2Fwww.nytimes.com%2F2015%2F05%2F12%2Fscience%2Fjennifer-doudna-crispr-cas9-genetic-engineering.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-50"><a href="#cite_ref-50">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJinekChylinskiFonfaraHauer2012" class="citation journal cs1">Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E (August 2012). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286148">"A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity"</a>. Science. 337 (6096): 816–21. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2012Sci...337..816J">2012Sci...337..816J</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.1225829">10.1126/science.1225829</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286148">6286148</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/22745249">22745249</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science&rft.atitle=A+programmable+dual-RNA-guided+DNA+endonuclease+in+adaptive+bacterial+immunity&rft.volume=337&rft.issue=6096&rft.pages=816-21&rft.date=2012-08&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6286148%23id-name%3DPMC&rft_id=info%3Apmid%2F22745249&rft_id=info%3Adoi%2F10.1126%2Fscience.1225829&rft_id=info%3Abibcode%2F2012Sci...337..816J&rft.aulast=Jinek&rft.aufirst=M&rft.au=Chylinski%2C+K&rft.au=Fonfara%2C+I&rft.au=Hauer%2C+M&rft.au=Doudna%2C+JA&rft.au=Charpentier%2C+E&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6286148&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-51"><a href="#cite_ref-51">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLedford2016" class="citation journal cs1">Ledford H (March 2016). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F531156a">"CRISPR: gene editing is just the beginning"</a>. Nature. 531 (7593): 156–9. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2016Natur.531..156L">2016Natur.531..156L</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F531156a">10.1038/531156a</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26961639">26961639</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=CRISPR%3A+gene+editing+is+just+the+beginning&rft.volume=531&rft.issue=7593&rft.pages=156-9&rft.date=2016-03&rft_id=info%3Apmid%2F26961639&rft_id=info%3Adoi%2F10.1038%2F531156a&rft_id=info%3Abibcode%2F2016Natur.531..156L&rft.aulast=Ledford&rft.aufirst=H&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252F531156a&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-52"><a href="#cite_ref-52">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKohKwonThomson2015" class="citation book cs1">Koh HJ, Kwon SY, Thomson M (26 August 2015). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=jWJ1CgAAQBAJ&pg=PA242">Current Technologies in Plant Molecular Breeding: A Guide Book of Plant Molecular Breeding for Researchers</a>. Springer. p. 242. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-94-017-9996-6" title="Special:BookSources/978-94-017-9996-6"><bdi>978-94-017-9996-6</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Current+Technologies+in+Plant+Molecular+Breeding%3A+A+Guide+Book+of+Plant+Molecular+Breeding+for+Researchers&rft.pages=242&rft.pub=Springer&rft.date=2015-08-26&rft.isbn=978-94-017-9996-6&rft.aulast=Koh&rft.aufirst=Hee-Jong&rft.au=Kwon%2C+Suk-Yoon&rft.au=Thomson%2C+Michael&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DjWJ1CgAAQBAJ%26pg%3DPA242&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-53"><a href="#cite_ref-53">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="http://sitn.hms.harvard.edu/flash/2015/how-to-make-a-gmo/">"How to Make a GMO"</a>. Science in the News. 9 August 2015. Retrieved 29 April 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science+in+the+News&rft.atitle=How+to+Make+a+GMO&rft.date=2015-08-09&rft_id=http%3A%2F%2Fsitn.hms.harvard.edu%2Fflash%2F2015%2Fhow-to-make-a-gmo%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-54"><a href="#cite_ref-54">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNicholl2008" class="citation book cs1">Nicholl, Desmond S.T. (29 May 2008). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=g1v6WMHVkTgC">An Introduction to Genetic Engineering</a>. Cambridge University Press. p. 34. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-139-47178-7" title="Special:BookSources/978-1-139-47178-7"><bdi>978-1-139-47178-7</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=An+Introduction+to+Genetic+Engineering&rft.pages=34&rft.pub=Cambridge+University+Press&rft.date=2008-05-29&rft.isbn=978-1-139-47178-7&rft.aulast=Nicholl&rft.aufirst=Desmond+S.T.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Dg1v6WMHVkTgC&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-55"><a href="#cite_ref-55">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAlbertsJohnsonLewis2002" class="citation book cs1">Alberts B, Johnson A, Lewis J, et al. (2002). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/books/NBK26837/">"Isolating, Cloning, and Sequencing DNA"</a>. Molecular Biology of the Cell (4th ed.). New York: Garland Science. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-8153-3218-1" title="Special:BookSources/0-8153-3218-1"><bdi>0-8153-3218-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Isolating%2C+Cloning%2C+and+Sequencing+DNA&rft.btitle=Molecular+Biology+of+the+Cell&rft.place=New+York&rft.edition=4th&rft.pub=Garland+Science&rft.date=2002&rft.isbn=0-8153-3218-1&rft.aulast=Alberts&rft.aufirst=B&rft.au=Johnson%2C+A&rft.au=Lewis%2C+J&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fbooks%2FNBK26837%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-56"><a href="#cite_ref-56">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKaufmanNixon1996" class="citation journal cs1">Kaufman RI, Nixon BT (July 1996). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC232662">"Use of PCR to isolate genes encoding sigma54-dependent activators from diverse bacteria"</a>. Journal of Bacteriology. 178 (13): 3967–70. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2Fjb.178.13.3967-3970.1996">10.1128/jb.178.13.3967-3970.1996</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC232662">232662</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8682806">8682806</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Bacteriology&rft.atitle=Use+of+PCR+to+isolate+genes+encoding+sigma54-dependent+activators+from+diverse+bacteria&rft.volume=178&rft.issue=13&rft.pages=3967-70&rft.date=1996-07&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC232662%23id-name%3DPMC&rft_id=info%3Apmid%2F8682806&rft_id=info%3Adoi%2F10.1128%2Fjb.178.13.3967-3970.1996&rft.aulast=Kaufman&rft.aufirst=RI&rft.au=Nixon%2C+BT&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC232662&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-57"><a href="#cite_ref-57">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLiangLuoZhao2011" class="citation journal cs1">Liang J, Luo Y, Zhao H (2011). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057768">"Synthetic biology: putting synthesis into biology"</a>. Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 3 (1): 7–20. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fwsbm.104">10.1002/wsbm.104</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057768">3057768</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21064036">21064036</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Wiley+Interdisciplinary+Reviews%3A+Systems+Biology+and+Medicine&rft.atitle=Synthetic+biology%3A+putting+synthesis+into+biology&rft.volume=3&rft.issue=1&rft.pages=7-20&rft.date=2011&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3057768%23id-name%3DPMC&rft_id=info%3Apmid%2F21064036&rft_id=info%3Adoi%2F10.1002%2Fwsbm.104&rft.aulast=Liang&rft.aufirst=J&rft.au=Luo%2C+Y&rft.au=Zhao%2C+H&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3057768&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-58"><a href="#cite_ref-58">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.fao.org/docrep/006/y4955e/y4955e06.htm">"5. The Process of Genetic Modification"</a>. www.fao.org. Retrieved 29 April 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.fao.org&rft.atitle=5.+The+Process+of+Genetic+Modification&rft_id=http%3A%2F%2Fwww.fao.org%2Fdocrep%2F006%2Fy4955e%2Fy4955e06.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-59"><a href="#cite_ref-59">^</a> J M Blatny, T Brautaset, C H Winther-Larsen, K Haugan and S Valla: "Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon", Appl. Environ. Microbiol. 1997, Volume 63, Issue 2, p. 370 </li> <li id="cite_note-60"><a href="#cite_ref-60">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBergMertz2010" class="citation journal cs1">Berg P, Mertz JE (January 2010). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815933">"Personal reflections on the origins and emergence of recombinant DNA technology"</a>. Genetics. 184 (1): 9–17. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1534%2Fgenetics.109.112144">10.1534/genetics.109.112144</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815933">2815933</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20061565">20061565</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genetics&rft.atitle=Personal+reflections+on+the+origins+and+emergence+of+recombinant+DNA+technology&rft.volume=184&rft.issue=1&rft.pages=9-17&rft.date=2010-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2815933%23id-name%3DPMC&rft_id=info%3Apmid%2F20061565&rft_id=info%3Adoi%2F10.1534%2Fgenetics.109.112144&rft.aulast=Berg&rft.aufirst=P&rft.au=Mertz%2C+JE&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2815933&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-61"><a href="#cite_ref-61">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChenDubnau2004" class="citation journal cs1">Chen I, Dubnau D (March 2004). "DNA uptake during bacterial transformation". Nature Reviews. Microbiology. 2 (3): 241–9. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnrmicro844">10.1038/nrmicro844</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15083159">15083159</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:205499369">205499369</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+Reviews.+Microbiology&rft.atitle=DNA+uptake+during+bacterial+transformation&rft.volume=2&rft.issue=3&rft.pages=241-9&rft.date=2004-03&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A205499369%23id-name%3DS2CID&rft_id=info%3Apmid%2F15083159&rft_id=info%3Adoi%2F10.1038%2Fnrmicro844&rft.aulast=Chen&rft.aufirst=I&rft.au=Dubnau%2C+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-62"><a href="#cite_ref-62">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNational_Research_Council_(US)_Committee_on_Identifying_and_Assessing_Unintended_Effects_of_Genetically_Engineered_Foods_on_Human_Health2004" class="citation book cs1">National Research Council (US) Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health (1 January 2004). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/books/NBK215771/">Methods and Mechanisms for Genetic Manipulation of Plants, Animals, and Microorganisms</a>. National Academies Press (US).</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Methods+and+Mechanisms+for+Genetic+Manipulation+of+Plants%2C+Animals%2C+and+Microorganisms&rft.pub=National+Academies+Press+%28US%29&rft.date=2004-01-01&rft.au=National+Research+Council+%28US%29+Committee+on+Identifying+and+Assessing+Unintended+Effects+of+Genetically+Engineered+Foods+on+Human+Health&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fbooks%2FNBK215771%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-63"><a href="#cite_ref-63">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGelvin2003" class="citation journal cs1">Gelvin SB (March 2003). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150518">"Agrobacterium-mediated plant transformation: the biology behind the "gene-jockeying" tool"</a>. Microbiology and Molecular Biology Reviews. 67 (1): 16–37, table of contents. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FMMBR.67.1.16-37.2003">10.1128/MMBR.67.1.16-37.2003</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150518">150518</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12626681">12626681</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Microbiology+and+Molecular+Biology+Reviews&rft.atitle=Agrobacterium-mediated+plant+transformation%3A+the+biology+behind+the+%22gene-jockeying%22+tool&rft.volume=67&rft.issue=1&rft.pages=16-37%2C+table+of+contents&rft.date=2003-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC150518%23id-name%3DPMC&rft_id=info%3Apmid%2F12626681&rft_id=info%3Adoi%2F10.1128%2FMMBR.67.1.16-37.2003&rft.aulast=Gelvin&rft.aufirst=SB&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC150518&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-64"><a href="#cite_ref-64">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHeadHullTzotzos2009" class="citation book cs1">Head G, Hull RH, Tzotzos GT (2009). <a rel="nofollow" class="external text" href="https://archive.org/details/geneticallymodif00hull">Genetically Modified Plants: Assessing Safety and Managing Risk</a>. London: Academic Pr. p. <a rel="nofollow" class="external text" href="https://archive.org/details/geneticallymodif00hull/page/n254">244</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-12-374106-6" title="Special:BookSources/978-0-12-374106-6"><bdi>978-0-12-374106-6</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Genetically+Modified+Plants%3A+Assessing+Safety+and+Managing+Risk&rft.place=London&rft.pages=244&rft.pub=Academic+Pr&rft.date=2009&rft.isbn=978-0-12-374106-6&rft.aulast=Head&rft.aufirst=Graham&rft.au=Hull%2C+Roger+H&rft.au=Tzotzos%2C+George+T.&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fgeneticallymodif00hull&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-65"><a href="#cite_ref-65">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTuomelaStanescuKrohn2005" class="citation journal cs1 cs1-prop-long-vol">Tuomela M, Stanescu I, Krohn K (October 2005). "Validation overview of bio-analytical methods". Gene Therapy. 12 Suppl 1 (S1): S131-8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.gt.3302627">10.1038/sj.gt.3302627</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16231045">16231045</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:23000818">23000818</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Gene+Therapy&rft.atitle=Validation+overview+of+bio-analytical+methods&rft.volume=12+Suppl+1&rft.issue=S1&rft.pages=S131-8&rft.date=2005-10&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A23000818%23id-name%3DS2CID&rft_id=info%3Apmid%2F16231045&rft_id=info%3Adoi%2F10.1038%2Fsj.gt.3302627&rft.aulast=Tuomela&rft.aufirst=M&rft.au=Stanescu%2C+I&rft.au=Krohn%2C+K&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-66"><a href="#cite_ref-66">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNarayanaswamy1994" class="citation book cs1">Narayanaswamy, S. (1994). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=-M4lR-pxqJMC">Plant Cell and Tissue Culture</a>. Tata McGraw-Hill Education. p. vi. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-07-460277-5" title="Special:BookSources/978-0-07-460277-5"><bdi>978-0-07-460277-5</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Plant+Cell+and+Tissue+Culture&rft.pages=vi&rft.pub=Tata+McGraw-Hill+Education&rft.date=1994&rft.isbn=978-0-07-460277-5&rft.aulast=Narayanaswamy&rft.aufirst=S.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D-M4lR-pxqJMC&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-67"><a href="#cite_ref-67">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNational_Research_Council_(US)_Committee_on_Identifying_and_Assessing_Unintended_Effects_of_Genetically_Engineered_Foods_on_Human_Health2004" class="citation book cs1">National Research Council (US) Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health (2004). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/books/NBK215771/">Methods and Mechanisms for Genetic Manipulation of Plants, Animals, and Microorganisms</a>. National Academies Press (US).</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Methods+and+Mechanisms+for+Genetic+Manipulation+of+Plants%2C+Animals%2C+and+Microorganisms&rft.pub=National+Academies+Press+%28US%29&rft.date=2004&rft.au=National+Research+Council+%28US%29+Committee+on+Identifying+and+Assessing+Unintended+Effects+of+Genetically+Engineered+Foods+on+Human+Health&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fbooks%2FNBK215771%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-68"><a href="#cite_ref-68">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHohnLevyPuchta2001" class="citation journal cs1">Hohn B, Levy AA, Puchta H (April 2001). "Elimination of selection markers from transgenic plants". Current Opinion in Biotechnology. 12 (2): 139–43. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0958-1669%2800%2900188-9">10.1016/S0958-1669(00)00188-9</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11287227">11287227</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Current+Opinion+in+Biotechnology&rft.atitle=Elimination+of+selection+markers+from+transgenic+plants&rft.volume=12&rft.issue=2&rft.pages=139-43&rft.date=2001-04&rft_id=info%3Adoi%2F10.1016%2FS0958-1669%2800%2900188-9&rft_id=info%3Apmid%2F11287227&rft.aulast=Hohn&rft.aufirst=B&rft.au=Levy%2C+AA&rft.au=Puchta%2C+H&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-69"><a href="#cite_ref-69">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSetlow2002" class="citation book cs1">Setlow JK (31 October 2002). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=aGkXFmqOcyIC">Genetic Engineering: Principles and Methods</a>. Springer Science & Business Media. p. 109. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-306-47280-0" title="Special:BookSources/978-0-306-47280-0"><bdi>978-0-306-47280-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Genetic+Engineering%3A+Principles+and+Methods&rft.pages=109&rft.pub=Springer+Science+%26+Business+Media&rft.date=2002-10-31&rft.isbn=978-0-306-47280-0&rft.aulast=Setlow&rft.aufirst=Jane+K.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DaGkXFmqOcyIC&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-70"><a href="#cite_ref-70">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDeepakKottapalliRakwalOros2007" class="citation journal cs1">Deepak S, Kottapalli K, Rakwal R, Oros G, Rangappa K, Iwahashi H, Masuo Y, Agrawal G (June 2007). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430684">"Real-Time PCR: Revolutionizing Detection and Expression Analysis of Genes"</a>. Current Genomics. 8 (4): 234–51. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2174%2F138920207781386960">10.2174/138920207781386960</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430684">2430684</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18645596">18645596</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Current+Genomics&rft.atitle=Real-Time+PCR%3A+Revolutionizing+Detection+and+Expression+Analysis+of+Genes&rft.volume=8&rft.issue=4&rft.pages=234-51&rft.date=2007-06&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2430684%23id-name%3DPMC&rft_id=info%3Apmid%2F18645596&rft_id=info%3Adoi%2F10.2174%2F138920207781386960&rft.aulast=Deepak&rft.aufirst=S&rft.au=Kottapalli%2C+K&rft.au=Rakwal%2C+R&rft.au=Oros%2C+G&rft.au=Rangappa%2C+K&rft.au=Iwahashi%2C+H&rft.au=Masuo%2C+Y&rft.au=Agrawal%2C+G&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2430684&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-71"><a href="#cite_ref-71">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGrizotSmithDaboussiPrieto2009" class="citation journal cs1">Grizot S, Smith J, Daboussi F, Prieto J, Redondo P, Merino N, Villate M, Thomas S, Lemaire L, Montoya G, Blanco FJ, Pâques F, Duchateau P (September 2009). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760784">"Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease"</a>. Nucleic Acids Research. 37 (16): 5405–19. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkp548">10.1093/nar/gkp548</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760784">2760784</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19584299">19584299</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nucleic+Acids+Research&rft.atitle=Efficient+targeting+of+a+SCID+gene+by+an+engineered+single-chain+homing+endonuclease&rft.volume=37&rft.issue=16&rft.pages=5405-19&rft.date=2009-09&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2760784%23id-name%3DPMC&rft_id=info%3Apmid%2F19584299&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkp548&rft.aulast=Grizot&rft.aufirst=S&rft.au=Smith%2C+J&rft.au=Daboussi%2C+F&rft.au=Prieto%2C+J&rft.au=Redondo%2C+P&rft.au=Merino%2C+N&rft.au=Villate%2C+M&rft.au=Thomas%2C+S&rft.au=Lemaire%2C+L&rft.au=Montoya%2C+G&rft.au=Blanco%2C+FJ&rft.au=P%C3%A2ques%2C+F&rft.au=Duchateau%2C+P&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2760784&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-72"><a href="#cite_ref-72">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGaoSmithYangJones2010" class="citation journal cs1">Gao H, Smith J, Yang M, Jones S, Djukanovic V, Nicholson MG, West A, Bidney D, Falco SC, Jantz D, Lyznik LA (January 2010). "Heritable targeted mutagenesis in maize using a designed endonuclease". The Plant Journal. 61 (1): 176–87. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1365-313X.2009.04041.x">10.1111/j.1365-313X.2009.04041.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19811621">19811621</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Plant+Journal&rft.atitle=Heritable+targeted+mutagenesis+in+maize+using+a+designed+endonuclease&rft.volume=61&rft.issue=1&rft.pages=176-87&rft.date=2010-01&rft_id=info%3Adoi%2F10.1111%2Fj.1365-313X.2009.04041.x&rft_id=info%3Apmid%2F19811621&rft.aulast=Gao&rft.aufirst=H&rft.au=Smith%2C+J&rft.au=Yang%2C+M&rft.au=Jones%2C+S&rft.au=Djukanovic%2C+V&rft.au=Nicholson%2C+MG&rft.au=West%2C+A&rft.au=Bidney%2C+D&rft.au=Falco%2C+SC&rft.au=Jantz%2C+D&rft.au=Lyznik%2C+LA&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-73"><a href="#cite_ref-73">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTownsendWrightWinfreyFu2009" class="citation journal cs1">Townsend JA, Wright DA, Winfrey RJ, Fu F, Maeder ML, Joung JK, Voytas DF (May 2009). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743854">"High-frequency modification of plant genes using engineered zinc-finger nucleases"</a>. Nature. 459 (7245): 442–5. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2009Natur.459..442T">2009Natur.459..442T</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnature07845">10.1038/nature07845</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743854">2743854</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19404258">19404258</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=High-frequency+modification+of+plant+genes+using+engineered+zinc-finger+nucleases&rft.volume=459&rft.issue=7245&rft.pages=442-5&rft.date=2009-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2743854%23id-name%3DPMC&rft_id=info%3Apmid%2F19404258&rft_id=info%3Adoi%2F10.1038%2Fnature07845&rft_id=info%3Abibcode%2F2009Natur.459..442T&rft.aulast=Townsend&rft.aufirst=JA&rft.au=Wright%2C+DA&rft.au=Winfrey%2C+RJ&rft.au=Fu%2C+F&rft.au=Maeder%2C+ML&rft.au=Joung%2C+JK&rft.au=Voytas%2C+DF&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2743854&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-74"><a href="#cite_ref-74">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFShuklaDoyonMillerDeKelver2009" class="citation journal cs1">Shukla VK, Doyon Y, Miller JC, DeKelver RC, Moehle EA, Worden SE, Mitchell JC, Arnold NL, Gopalan S, Meng X, Choi VM, Rock JM, Wu YY, Katibah GE, Zhifang G, McCaskill D, Simpson MA, Blakeslee B, Greenwalt SA, Butler HJ, Hinkley SJ, Zhang L, Rebar EJ, Gregory PD, Urnov FD (May 2009). "Precise genome modification in the crop species Zea mays using zinc-finger nucleases". Nature. 459 (7245): 437–41. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2009Natur.459..437S">2009Natur.459..437S</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnature07992">10.1038/nature07992</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19404259">19404259</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:4323298">4323298</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Precise+genome+modification+in+the+crop+species+Zea+mays+using+zinc-finger+nucleases&rft.volume=459&rft.issue=7245&rft.pages=437-41&rft.date=2009-05&rft_id=info%3Adoi%2F10.1038%2Fnature07992&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A4323298%23id-name%3DS2CID&rft_id=info%3Apmid%2F19404259&rft_id=info%3Abibcode%2F2009Natur.459..437S&rft.aulast=Shukla&rft.aufirst=VK&rft.au=Doyon%2C+Y&rft.au=Miller%2C+JC&rft.au=DeKelver%2C+RC&rft.au=Moehle%2C+EA&rft.au=Worden%2C+SE&rft.au=Mitchell%2C+JC&rft.au=Arnold%2C+NL&rft.au=Gopalan%2C+S&rft.au=Meng%2C+X&rft.au=Choi%2C+VM&rft.au=Rock%2C+JM&rft.au=Wu%2C+YY&rft.au=Katibah%2C+GE&rft.au=Zhifang%2C+G&rft.au=McCaskill%2C+D&rft.au=Simpson%2C+MA&rft.au=Blakeslee%2C+B&rft.au=Greenwalt%2C+SA&rft.au=Butler%2C+HJ&rft.au=Hinkley%2C+SJ&rft.au=Zhang%2C+L&rft.au=Rebar%2C+EJ&rft.au=Gregory%2C+PD&rft.au=Urnov%2C+FD&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-75"><a href="#cite_ref-75">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChristianCermakDoyleSchmidt2010" class="citation journal cs1">Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, Hummel A, Bogdanove AJ, Voytas DF (October 2010). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942870">"Targeting DNA double-strand breaks with TAL effector nucleases"</a>. Genetics. 186 (2): 757–61. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1534%2Fgenetics.110.120717">10.1534/genetics.110.120717</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942870">2942870</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20660643">20660643</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genetics&rft.atitle=Targeting+DNA+double-strand+breaks+with+TAL+effector+nucleases&rft.volume=186&rft.issue=2&rft.pages=757-61&rft.date=2010-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2942870%23id-name%3DPMC&rft_id=info%3Apmid%2F20660643&rft_id=info%3Adoi%2F10.1534%2Fgenetics.110.120717&rft.aulast=Christian&rft.aufirst=M&rft.au=Cermak%2C+T&rft.au=Doyle%2C+EL&rft.au=Schmidt%2C+C&rft.au=Zhang%2C+F&rft.au=Hummel%2C+A&rft.au=Bogdanove%2C+AJ&rft.au=Voytas%2C+DF&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2942870&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-76"><a href="#cite_ref-76">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLiHuangJiangWright2011" class="citation journal cs1">Li T, Huang S, Jiang WZ, Wright D, Spalding MH, Weeks DP, Yang B (January 2011). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017587">"TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain"</a>. Nucleic Acids Research. 39 (1): 359–72. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkq704">10.1093/nar/gkq704</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017587">3017587</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20699274">20699274</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nucleic+Acids+Research&rft.atitle=TAL+nucleases+%28TALNs%29%3A+hybrid+proteins+composed+of+TAL+effectors+and+FokI+DNA-cleavage+domain&rft.volume=39&rft.issue=1&rft.pages=359-72&rft.date=2011-01&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3017587%23id-name%3DPMC&rft_id=info%3Apmid%2F20699274&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkq704&rft.aulast=Li&rft.aufirst=T&rft.au=Huang%2C+S&rft.au=Jiang%2C+WZ&rft.au=Wright%2C+D&rft.au=Spalding%2C+MH&rft.au=Weeks%2C+DP&rft.au=Yang%2C+B&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3017587&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-77"><a href="#cite_ref-77">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFEsveltWang2013" class="citation journal cs1">Esvelt KM, Wang HH (2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564264">"Genome-scale engineering for systems and synthetic biology"</a>. Molecular Systems Biology. 9: 641. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fmsb.2012.66">10.1038/msb.2012.66</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564264">3564264</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23340847">23340847</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Molecular+Systems+Biology&rft.atitle=Genome-scale+engineering+for+systems+and+synthetic+biology&rft.volume=9&rft.pages=641&rft.date=2013&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3564264%23id-name%3DPMC&rft_id=info%3Apmid%2F23340847&rft_id=info%3Adoi%2F10.1038%2Fmsb.2012.66&rft.aulast=Esvelt&rft.aufirst=KM&rft.au=Wang%2C+HH&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3564264&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-78"><a href="#cite_ref-78">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTanCarlsonWaltonFahrenkrug2012" class="citation book cs1">Tan WS, Carlson DF, Walton MW, Fahrenkrug SC, Hackett PB (2012). "Precision editing of large animal genomes". Advances in Genetics Volume 80. Vol. 80. pp. 37–97. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FB978-0-12-404742-6.00002-8">10.1016/B978-0-12-404742-6.00002-8</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-12-404742-6" title="Special:BookSources/978-0-12-404742-6"><bdi>978-0-12-404742-6</bdi></a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683964">3683964</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23084873">23084873</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Precision+editing+of+large+animal+genomes&rft.btitle=Advances+in+Genetics+Volume+80&rft.pages=37-97&rft.date=2012&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3683964%23id-name%3DPMC&rft_id=info%3Apmid%2F23084873&rft_id=info%3Adoi%2F10.1016%2FB978-0-12-404742-6.00002-8&rft.isbn=978-0-12-404742-6&rft.aulast=Tan&rft.aufirst=WS&rft.au=Carlson%2C+DF&rft.au=Walton%2C+MW&rft.au=Fahrenkrug%2C+SC&rft.au=Hackett%2C+PB&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:5-79">^ <a href="#cite_ref-:5_79-0">a</a> <a href="#cite_ref-:5_79-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMalzahnLowderQi2017" class="citation journal cs1">Malzahn A, Lowder L, Qi Y (24 April 2017). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404292">"Plant genome editing with TALEN and CRISPR"</a>. Cell & Bioscience. 7: 21. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1186%2Fs13578-017-0148-4">10.1186/s13578-017-0148-4</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404292">5404292</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/28451378">28451378</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cell+%26+Bioscience&rft.atitle=Plant+genome+editing+with+TALEN+and+CRISPR&rft.volume=7&rft.pages=21&rft.date=2017-04-24&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5404292%23id-name%3DPMC&rft_id=info%3Apmid%2F28451378&rft_id=info%3Adoi%2F10.1186%2Fs13578-017-0148-4&rft.aulast=Malzahn&rft.aufirst=A&rft.au=Lowder%2C+L&rft.au=Qi%2C+Y&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5404292&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-80"><a href="#cite_ref-80">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFEkker2008" class="citation journal cs1">Ekker SC (2008). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849655">"Zinc finger-based knockout punches for zebrafish genes"</a>. Zebrafish. 5 (2): 121–3. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1089%2Fzeb.2008.9988">10.1089/zeb.2008.9988</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849655">2849655</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18554175">18554175</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Zebrafish&rft.atitle=Zinc+finger-based+knockout+punches+for+zebrafish+genes&rft.volume=5&rft.issue=2&rft.pages=121-3&rft.date=2008&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2849655%23id-name%3DPMC&rft_id=info%3Apmid%2F18554175&rft_id=info%3Adoi%2F10.1089%2Fzeb.2008.9988&rft.aulast=Ekker&rft.aufirst=SC&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2849655&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-81"><a href="#cite_ref-81">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGeurtsCostFreyvertZeitler2009" class="citation journal cs1">Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, Kalloway S, Weiler H, Ménoret S, Anegon I, Davis GD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jacob HJ, Buelow R (July 2009). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831805">"Knockout rats via embryo microinjection of zinc-finger nucleases"</a>. Science. 325 (5939): 433. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2009Sci...325..433G">2009Sci...325..433G</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.1172447">10.1126/science.1172447</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831805">2831805</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19628861">19628861</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science&rft.atitle=Knockout+rats+via+embryo+microinjection+of+zinc-finger+nucleases&rft.volume=325&rft.issue=5939&rft.pages=433&rft.date=2009-07&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2831805%23id-name%3DPMC&rft_id=info%3Apmid%2F19628861&rft_id=info%3Adoi%2F10.1126%2Fscience.1172447&rft_id=info%3Abibcode%2F2009Sci...325..433G&rft.aulast=Geurts&rft.aufirst=AM&rft.au=Cost%2C+GJ&rft.au=Freyvert%2C+Y&rft.au=Zeitler%2C+B&rft.au=Miller%2C+JC&rft.au=Choi%2C+VM&rft.au=Jenkins%2C+SS&rft.au=Wood%2C+A&rft.au=Cui%2C+X&rft.au=Meng%2C+X&rft.au=Vincent%2C+A&rft.au=Lam%2C+S&rft.au=Michalkiewicz%2C+M&rft.au=Schilling%2C+R&rft.au=Foeckler%2C+J&rft.au=Kalloway%2C+S&rft.au=Weiler%2C+H&rft.au=M%C3%A9noret%2C+S&rft.au=Anegon%2C+I&rft.au=Davis%2C+GD&rft.au=Zhang%2C+L&rft.au=Rebar%2C+EJ&rft.au=Gregory%2C+PD&rft.au=Urnov%2C+FD&rft.au=Jacob%2C+HJ&rft.au=Buelow%2C+R&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2831805&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-82"><a href="#cite_ref-82">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20131224110848/http://www.learner.org/courses/biology/textbook/gmo/gmo_2.html">"Genetic Modification of Bacteria"</a>. <a href="/wiki/Annenberg_Foundation" title="Annenberg Foundation">Annenberg Foundation</a>. Archived from <a rel="nofollow" class="external text" href="http://www.learner.org/courses/biology/textbook/gmo/gmo_2.html">the original</a> on 24 December 2013. Retrieved 4 October 2012.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Genetic+Modification+of+Bacteria&rft.pub=Annenberg+Foundation&rft_id=http%3A%2F%2Fwww.learner.org%2Fcourses%2Fbiology%2Ftextbook%2Fgmo%2Fgmo_2.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-83"><a href="#cite_ref-83">^</a> Panesar, Pamit et al. (2010) "Enzymes in Food Processing: Fundamentals and Potential Applications", Chapter 10, I K International Publishing House, <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-93-80026-33-6" title="Special:BookSources/978-93-80026-33-6">978-93-80026-33-6</a> </li> <li id="cite_note-84"><a href="#cite_ref-84">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.isaaa.org/gmapprovaldatabase/gmtraitslist/default.asp">"GM traits list"</a>. International Service for the Acquisition of Agri-Biotech Applications.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=GM+traits+list&rft.pub=International+Service+for+the+Acquisition+of+Agri-Biotech+Applications&rft_id=http%3A%2F%2Fwww.isaaa.org%2Fgmapprovaldatabase%2Fgmtraitslist%2Fdefault.asp&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-85"><a href="#cite_ref-85">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.isaaa.org/resources/publications/briefs/43/executivesummary/default.asp">"ISAAA Brief 43-2011: Executive Summary"</a>. International Service for the Acquisition of Agri-Biotech Applications.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=ISAAA+Brief+43-2011%3A+Executive+Summary&rft.pub=International+Service+for+the+Acquisition+of+Agri-Biotech+Applications&rft_id=http%3A%2F%2Fwww.isaaa.org%2Fresources%2Fpublications%2Fbriefs%2F43%2Fexecutivesummary%2Fdefault.asp&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-86"><a href="#cite_ref-86">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFConnor2007" class="citation news cs1">Connor S (2 November 2007). <a rel="nofollow" class="external text" href="https://www.independent.co.uk/news/science/the-mouse-that-shook-the-world-744870.html">"The mouse that shook the world"</a>. The Independent.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Independent&rft.atitle=The+mouse+that+shook+the+world&rft.date=2007-11-02&rft.aulast=Connor&rft.aufirst=Steve&rft_id=https%3A%2F%2Fwww.independent.co.uk%2Fnews%2Fscience%2Fthe-mouse-that-shook-the-world-744870.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-87"><a href="#cite_ref-87">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAvise2004" class="citation book cs1">Avise JC (2004). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=gR8cWf2-UY4C">The hope, hype & reality of genetic engineering: remarkable stories from agriculture, industry, medicine, and the environment</a>. Oxford University Press US. p. 22. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-19-516950-8" title="Special:BookSources/978-0-19-516950-8"><bdi>978-0-19-516950-8</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+hope%2C+hype+%26+reality+of+genetic+engineering%3A+remarkable+stories+from+agriculture%2C+industry%2C+medicine%2C+and+the+environment&rft.pages=22&rft.pub=Oxford+University+Press+US&rft.date=2004&rft.isbn=978-0-19-516950-8&rft.aulast=Avise&rft.aufirst=John+C.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DgR8cWf2-UY4C&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-88"><a href="#cite_ref-88">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="http://phys.org/news/2012-12-algae-complex-anti-cancer-drug.html">"Engineering algae to make complex anti-cancer 'designer' drug"</a>. PhysOrg. 10 December 2012. Retrieved 15 April 2013.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PhysOrg&rft.atitle=Engineering+algae+to+make+complex+anti-cancer+%27designer%27+drug&rft.date=2012-12-10&rft_id=http%3A%2F%2Fphys.org%2Fnews%2F2012-12-algae-complex-anti-cancer-drug.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-89"><a href="#cite_ref-89">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRoqueLoweTaipa2004" class="citation journal cs1">Roque AC, Lowe CR, Taipa MA (2004). "Antibodies and genetically engineered related molecules: production and purification". Biotechnology Progress. 20 (3): 639–54. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1021%2Fbp030070k">10.1021/bp030070k</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15176864">15176864</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:23142893">23142893</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biotechnology+Progress&rft.atitle=Antibodies+and+genetically+engineered+related+molecules%3A+production+and+purification&rft.volume=20&rft.issue=3&rft.pages=639-54&rft.date=2004&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A23142893%23id-name%3DS2CID&rft_id=info%3Apmid%2F15176864&rft_id=info%3Adoi%2F10.1021%2Fbp030070k&rft.aulast=Roque&rft.aufirst=AC&rft.au=Lowe%2C+CR&rft.au=Taipa%2C+MA&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-90"><a href="#cite_ref-90">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRodriguezGrubman2009" class="citation journal cs1">Rodriguez LL, Grubman MJ (November 2009). "Foot and mouth disease virus vaccines". Vaccine. 27 (Suppl 4): D90-4. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.vaccine.2009.08.039">10.1016/j.vaccine.2009.08.039</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19837296">19837296</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Foot+and+mouth+disease+virus+vaccines&rft.volume=27&rft.issue=Suppl+4&rft.pages=D90-4&rft.date=2009-11&rft_id=info%3Adoi%2F10.1016%2Fj.vaccine.2009.08.039&rft_id=info%3Apmid%2F19837296&rft.aulast=Rodriguez&rft.aufirst=LL&rft.au=Grubman%2C+MJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-91"><a href="#cite_ref-91">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20161123110939/http://geneticsandsociety.org/article.php?id=386">"Background: Cloned and Genetically Modified Animals"</a>. Center for Genetics and Society. 14 April 2005. Archived from <a rel="nofollow" class="external text" href="http://www.geneticsandsociety.org/article.php?id=386">the original</a> on 23 November 2016. Retrieved 9 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Background%3A+Cloned+and+Genetically+Modified+Animals&rft.pub=Center+for+Genetics+and+Society&rft.date=2005-04-14&rft_id=http%3A%2F%2Fwww.geneticsandsociety.org%2Farticle.php%3Fid%3D386&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-92"><a href="#cite_ref-92">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.genome.gov/12514551">"Knockout Mice"</a>. Nation Human Genome Research Institute. 2009.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Knockout+Mice&rft.pub=Nation+Human+Genome+Research+Institute&rft.date=2009&rft_id=http%3A%2F%2Fwww.genome.gov%2F12514551&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-93"><a href="#cite_ref-93">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFischerHacein-Bey-AbinaCavazzana-Calvo2010" class="citation journal cs1">Fischer A, Hacein-Bey-Abina S, Cavazzana-Calvo M (June 2010). "20 years of gene therapy for SCID". Nature Immunology. 11 (6): 457–60. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fni0610-457">10.1038/ni0610-457</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20485269">20485269</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:11300348">11300348</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+Immunology&rft.atitle=20+years+of+gene+therapy+for+SCID&rft.volume=11&rft.issue=6&rft.pages=457-60&rft.date=2010-06&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A11300348%23id-name%3DS2CID&rft_id=info%3Apmid%2F20485269&rft_id=info%3Adoi%2F10.1038%2Fni0610-457&rft.aulast=Fischer&rft.aufirst=A&rft.au=Hacein-Bey-Abina%2C+S&rft.au=Cavazzana-Calvo%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Porter-94"><a href="#cite_ref-Porter_94-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLedford2011" class="citation journal cs1">Ledford H (2011). "Cell therapy fights leukaemia". Nature. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnews.2011.472">10.1038/news.2011.472</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Cell+therapy+fights+leukaemia&rft.date=2011&rft_id=info%3Adoi%2F10.1038%2Fnews.2011.472&rft.aulast=Ledford&rft.aufirst=Heidi&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-95"><a href="#cite_ref-95">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBrentjensDavilaRivierePark2013" class="citation journal cs1">Brentjens RJ, Davila ML, Riviere I, Park J, Wang X, Cowell LG, et al. (March 2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742551">"CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia"</a>. Science Translational Medicine. 5 (177): 177ra38. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscitranslmed.3005930">10.1126/scitranslmed.3005930</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742551">3742551</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23515080">23515080</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science+Translational+Medicine&rft.atitle=CD19-targeted+T+cells+rapidly+induce+molecular+remissions+in+adults+with+chemotherapy-refractory+acute+lymphoblastic+leukemia&rft.volume=5&rft.issue=177&rft.pages=177ra38&rft.date=2013-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3742551%23id-name%3DPMC&rft_id=info%3Apmid%2F23515080&rft_id=info%3Adoi%2F10.1126%2Fscitranslmed.3005930&rft.aulast=Brentjens&rft.aufirst=RJ&rft.au=Davila%2C+ML&rft.au=Riviere%2C+I&rft.au=Park%2C+J&rft.au=Wang%2C+X&rft.au=Cowell%2C+LG&rft.au=Bartido%2C+S&rft.au=Stefanski%2C+J&rft.au=Taylor%2C+C&rft.au=Olszewska%2C+M&rft.au=Borquez-Ojeda%2C+O&rft.au=Qu%2C+J&rft.au=Wasielewska%2C+T&rft.au=He%2C+Q&rft.au=Bernal%2C+Y&rft.au=Rijo%2C+IV&rft.au=Hedvat%2C+C&rft.au=Kobos%2C+R&rft.au=Curran%2C+K&rft.au=Steinherz%2C+P&rft.au=Jurcic%2C+J&rft.au=Rosenblat%2C+T&rft.au=Maslak%2C+P&rft.au=Frattini%2C+M&rft.au=Sadelain%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3742551&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-96"><a href="#cite_ref-96">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLeWittRezaiLeeheyOjemann2011" class="citation journal cs1">LeWitt PA, Rezai AR, Leehey MA, Ojemann SG, Flaherty AW, Eskandar EN, et al. (April 2011). "AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial". The Lancet. Neurology. 10 (4): 309–19. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS1474-4422%2811%2970039-4">10.1016/S1474-4422(11)70039-4</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21419704">21419704</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:37154043">37154043</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Lancet.+Neurology&rft.atitle=AAV2-GAD+gene+therapy+for+advanced+Parkinson%27s+disease%3A+a+double-blind%2C+sham-surgery+controlled%2C+randomised+trial&rft.volume=10&rft.issue=4&rft.pages=309-19&rft.date=2011-04&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A37154043%23id-name%3DS2CID&rft_id=info%3Apmid%2F21419704&rft_id=info%3Adoi%2F10.1016%2FS1474-4422%2811%2970039-4&rft.aulast=LeWitt&rft.aufirst=PA&rft.au=Rezai%2C+AR&rft.au=Leehey%2C+MA&rft.au=Ojemann%2C+SG&rft.au=Flaherty%2C+AW&rft.au=Eskandar%2C+EN&rft.au=Kostyk%2C+SK&rft.au=Thomas%2C+K&rft.au=Sarkar%2C+A&rft.au=Siddiqui%2C+MS&rft.au=Tatter%2C+SB&rft.au=Schwalb%2C+JM&rft.au=Poston%2C+KL&rft.au=Henderson%2C+JM&rft.au=Kurlan%2C+RM&rft.au=Richard%2C+IH&rft.au=Van+Meter%2C+L&rft.au=Sapan%2C+CV&rft.au=During%2C+MJ&rft.au=Kaplitt%2C+MG&rft.au=Feigin%2C+A&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Gallagher-97"><a href="#cite_ref-Gallagher_97-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="https://www.bbc.com/news/health-20179561">"Gene therapy: Glybera approved by European Commission"</a>. BBC News. 2 November 2012. Retrieved 30 March 2023.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=BBC+News&rft.atitle=Gene+therapy%3A+Glybera+approved+by+European+Commission&rft.date=2012-11-02&rft_id=https%3A%2F%2Fwww.bbc.com%2Fnews%2Fhealth-20179561&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Richards2012-98"><a href="#cite_ref-Richards2012_98-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRichards" class="citation web cs1">Richards S. <a rel="nofollow" class="external text" href="http://www.the-scientist.com/?articles.view/articleNo/33166/title/Gene-Therapy-Arrives-in-Europe/">"Gene Therapy Arrives in Europe"</a>. The Scientist. Retrieved 16 November 2012.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Gene+Therapy+Arrives+in+Europe&rft.pub=The+Scientist&rft.aulast=Richards&rft.aufirst=Sabrina&rft_id=http%3A%2F%2Fwww.the-scientist.com%2F%3Farticles.view%2FarticleNo%2F33166%2Ftitle%2FGene-Therapy-Arrives-in-Europe%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-99"><a href="#cite_ref-99">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="https://www.npr.org/2017/11/08/562647401/genetically-altered-skin-saves-a-boy-dying-of-a-rare-disease?sc=tw">"Genetically Altered Skin Saves A Boy Dying of a Rare Disease"</a>. NPR.org. Retrieved 15 November 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=NPR.org&rft.atitle=Genetically+Altered+Skin+Saves+A+Boy+Dying+of+a+Rare+Disease&rft_id=https%3A%2F%2Fwww.npr.org%2F2017%2F11%2F08%2F562647401%2Fgenetically-altered-skin-saves-a-boy-dying-of-a-rare-disease%3Fsc%3Dtw&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-100"><a href="#cite_ref-100">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20010805085535/http://www.cioms.ch/frame_1990_texts_of_guidelines.htm">"1990 The Declaration of Inuyama"</a>. 5 August 2001. Archived from the original on 5 August 2001.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=1990+The+Declaration+of+Inuyama&rft.date=2001-08-05&rft_id=http%3A%2F%2Fwww.cioms.ch%2Fframe_1990_texts_of_guidelines.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"><code class="cs1-code">{{<a href="/wiki/Template:Cite_web" title="Template:Cite web">cite web</a>}}</code>: CS1 maint: bot: original URL status unknown (<a href="/wiki/Category:CS1_maint:_bot:_original_URL_status_unknown" title="Category:CS1 maint: bot: original URL status unknown">link</a>) </li> <li id="cite_note-101"><a href="#cite_ref-101">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSmithChanHarris2012" class="citation journal cs1">Smith KR, Chan S, Harris J (October 2012). "Human germline genetic modification: scientific and bioethical perspectives". Archives of Medical Research. 43 (7): 491–513. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.arcmed.2012.09.003">10.1016/j.arcmed.2012.09.003</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23072719">23072719</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Archives+of+Medical+Research&rft.atitle=Human+germline+genetic+modification%3A+scientific+and+bioethical+perspectives&rft.volume=43&rft.issue=7&rft.pages=491-513&rft.date=2012-10&rft_id=info%3Adoi%2F10.1016%2Fj.arcmed.2012.09.003&rft_id=info%3Apmid%2F23072719&rft.aulast=Smith&rft.aufirst=KR&rft.au=Chan%2C+S&rft.au=Harris%2C+J&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-NYT-20150423-102"><a href="#cite_ref-NYT-20150423_102-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKolata2015" class="citation news cs1">Kolata G (23 April 2015). <a rel="nofollow" class="external text" href="https://www.nytimes.com/2015/04/24/health/chinese-scientists-edit-genes-of-human-embryos-raising-concerns.html">"Chinese Scientists Edit Genes of Human Embryos, Raising Concerns"</a>. The New York Times. <a rel="nofollow" class="external text" href="https://ghostarchive.org/archive/20220102/https://www.nytimes.com/2015/04/24/health/chinese-scientists-edit-genes-of-human-embryos-raising-concerns.html">Archived</a> from the original on 2 January 2022. Retrieved 24 April 2015.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+York+Times&rft.atitle=Chinese+Scientists+Edit+Genes+of+Human+Embryos%2C+Raising+Concerns&rft.date=2015-04-23&rft.aulast=Kolata&rft.aufirst=Gina&rft_id=https%3A%2F%2Fwww.nytimes.com%2F2015%2F04%2F24%2Fhealth%2Fchinese-scientists-edit-genes-of-human-embryos-raising-concerns.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-PC-20150418-103"><a href="#cite_ref-PC-20150418_103-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLiangXuZhangDing2015" class="citation journal cs1">Liang P, Xu Y, Zhang X, Ding C, Huang R, Zhang Z, et al. (May 2015). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417674">"CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes"</a>. Protein & Cell. 6 (5): 363–372. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs13238-015-0153-5">10.1007/s13238-015-0153-5</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417674">4417674</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25894090">25894090</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Protein+%26+Cell&rft.atitle=CRISPR%2FCas9-mediated+gene+editing+in+human+tripronuclear+zygotes&rft.volume=6&rft.issue=5&rft.pages=363-372&rft.date=2015-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4417674%23id-name%3DPMC&rft_id=info%3Apmid%2F25894090&rft_id=info%3Adoi%2F10.1007%2Fs13238-015-0153-5&rft.aulast=Liang&rft.aufirst=P&rft.au=Xu%2C+Y&rft.au=Zhang%2C+X&rft.au=Ding%2C+C&rft.au=Huang%2C+R&rft.au=Zhang%2C+Z&rft.au=Lv%2C+J&rft.au=Xie%2C+X&rft.au=Chen%2C+Y&rft.au=Li%2C+Y&rft.au=Sun%2C+Y&rft.au=Bai%2C+Y&rft.au=Songyang%2C+Z&rft.au=Ma%2C+W&rft.au=Zhou%2C+C&rft.au=Huang%2C+J&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4417674&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-NYT-20151203-nw-104"><a href="#cite_ref-NYT-20151203-nw_104-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWade2015" class="citation news cs1"><a href="/wiki/Nicholas_Wade" title="Nicholas Wade">Wade N</a> (3 December 2015). <a rel="nofollow" class="external text" href="https://www.nytimes.com/2015/12/04/science/crispr-cas9-human-genome-editing-moratorium.html">"Scientists Place Moratorium on Edits to Human Genome That Could Be Inherited"</a>. The New York Times. <a rel="nofollow" class="external text" href="https://ghostarchive.org/archive/20220102/https://www.nytimes.com/2015/12/04/science/crispr-cas9-human-genome-editing-moratorium.html">Archived</a> from the original on 2 January 2022. Retrieved 3 December 2015.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+York+Times&rft.atitle=Scientists+Place+Moratorium+on+Edits+to+Human+Genome+That+Could+Be+Inherited&rft.date=2015-12-03&rft.aulast=Wade&rft.aufirst=Nicholas&rft_id=https%3A%2F%2Fwww.nytimes.com%2F2015%2F12%2F04%2Fscience%2Fcrispr-cas9-human-genome-editing-moratorium.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-105"><a href="#cite_ref-105">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBergeson1997" class="citation web cs1">Bergeson ER (1997). <a rel="nofollow" class="external text" href="http://www.ndsu.edu/pubweb/~mcclean/plsc431/students/bergeson.htm">"The Ethics of Gene Therapy"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=The+Ethics+of+Gene+Therapy&rft.date=1997&rft.aulast=Bergeson&rft.aufirst=Emilie+R.&rft_id=http%3A%2F%2Fwww.ndsu.edu%2Fpubweb%2F~mcclean%2Fplsc431%2Fstudents%2Fbergeson.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-106"><a href="#cite_ref-106">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHanna" class="citation web cs1">Hanna KE. <a rel="nofollow" class="external text" href="http://www.genome.gov/10004767">"Genetic Enhancement"</a>. National Human Genome Research Institute.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Genetic+Enhancement&rft.pub=National+Human+Genome+Research+Institute&rft.aulast=Hanna&rft.aufirst=Kathi+E.&rft_id=http%3A%2F%2Fwww.genome.gov%2F10004767&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-107"><a href="#cite_ref-107">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBegley2018" class="citation news cs1">Begley S (28 November 2018). <a rel="nofollow" class="external text" href="https://www.statnews.com/2018/11/28/chinese-scientist-defends-creating-gene-edited-babies/">"Amid uproar, Chinese scientist defends creating gene-edited babies – STAT"</a>. STAT.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=STAT&rft.atitle=Amid+uproar%2C+Chinese+scientist+defends+creating+gene-edited+babies+%E2%80%93+STAT&rft.date=2018-11-28&rft.aulast=Begley&rft.aufirst=Sharon&rft_id=https%3A%2F%2Fwww.statnews.com%2F2018%2F11%2F28%2Fchinese-scientist-defends-creating-gene-edited-babies%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-108"><a href="#cite_ref-108">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLi2020" class="citation journal cs1">Li, Emily (31 July 2020). <a rel="nofollow" class="external text" href="http://scholar.googleusercontent.com/scholar?q=cache:h6ILNa11QgIJ:scholar.google.com/+%E2%80%8BLi,+E.+(2020).+Risks+of+CRISPR+Gene+Editing+and+An+Answer+to+Them.+%E2%80%8BJournal+of+Clinical+and+Nursing+Research,%E2%80%8B+%E2%80%8B4(%E2%80%8B+4).&hl=en&as_sdt=0,21">"Diagnostic Value of Spiral CT Chest Enhanced Scan"</a>. Journal of Clinical and Nursing Research.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+and+Nursing+Research&rft.atitle=Diagnostic+Value+of+Spiral+CT+Chest+Enhanced+Scan&rft.date=2020-07-31&rft.aulast=Li&rft.aufirst=Emily&rft_id=http%3A%2F%2Fscholar.googleusercontent.com%2Fscholar%3Fq%3Dcache%3Ah6ILNa11QgIJ%3Ascholar.google.com%2F%2B%25E2%2580%258BLi%2C%2BE.%2B%282020%29.%2BRisks%2Bof%2BCRISPR%2BGene%2BEditing%2Band%2BAn%2BAnswer%2Bto%2BThem.%2B%25E2%2580%258BJournal%2Bof%2BClinical%2Band%2BNursing%2BResearch%2C%25E2%2580%258B%2B%25E2%2580%258B4%28%25E2%2580%258B%2B4%29.%26hl%3Den%26as_sdt%3D0%2C21&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Medical_News_Today-109"><a href="#cite_ref-Medical_News_Today_109-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20110510121726/http://www.medicalnewstoday.com/articles/4344.php">"GM pigs best bet for organ transplant"</a>. Medical News Today. 21 September 2003. Archived from <a rel="nofollow" class="external text" href="http://www.medicalnewstoday.com/articles/4344.php">the original</a> on 10 May 2011. Retrieved 9 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Medical+News+Today&rft.atitle=GM+pigs+best+bet+for+organ+transplant&rft.date=2003-09-21&rft_id=http%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2F4344.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-110"><a href="#cite_ref-110">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHarmon2015" class="citation news cs1">Harmon A (26 November 2015). <a rel="nofollow" class="external text" href="https://www.nytimes.com/2015/11/27/us/2015-11-27-us-animal-gene-editing.html">"Open Season Is Seen in Gene Editing of Animals"</a>. The New York Times. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0362-4331">0362-4331</a>. <a rel="nofollow" class="external text" href="https://ghostarchive.org/archive/20220102/https://www.nytimes.com/2015/11/27/us/2015-11-27-us-animal-gene-editing.html">Archived</a> from the original on 2 January 2022. Retrieved 27 September 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+York+Times&rft.atitle=Open+Season+Is+Seen+in+Gene+Editing+of+Animals&rft.date=2015-11-26&rft.issn=0362-4331&rft.aulast=Harmon&rft.aufirst=Amy&rft_id=https%3A%2F%2Fwww.nytimes.com%2F2015%2F11%2F27%2Fus%2F2015-11-27-us-animal-gene-editing.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-111"><a href="#cite_ref-111">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPraitisMaduro2011" class="citation book cs1">Praitis V, Maduro MF (2011). "Transgenesis in C. elegans". Caenorhabditis elegans: Molecular Genetics and Development. Methods in Cell Biology. Vol. 106. pp. 161–85. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FB978-0-12-544172-8.00006-2">10.1016/B978-0-12-544172-8.00006-2</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-12-544172-8" title="Special:BookSources/978-0-12-544172-8"><bdi>978-0-12-544172-8</bdi></a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/22118277">22118277</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Transgenesis+in+C.+elegans&rft.btitle=Caenorhabditis+elegans%3A+Molecular+Genetics+and+Development&rft.series=Methods+in+Cell+Biology&rft.pages=161-85&rft.date=2011&rft_id=info%3Apmid%2F22118277&rft_id=info%3Adoi%2F10.1016%2FB978-0-12-544172-8.00006-2&rft.isbn=978-0-12-544172-8&rft.aulast=Praitis&rft.aufirst=V&rft.au=Maduro%2C+MF&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-112"><a href="#cite_ref-112">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20191203123559/http://www.learner.org/courses/biology/textbook/gmo/gmo_2.html">"Rediscovering Biology – Online Textbook: Unit 13 Genetically Modified Organisms"</a>. www.learner.org. Archived from <a rel="nofollow" class="external text" href="https://www.learner.org/courses/biology/textbook/gmo/gmo_2.html">the original</a> on 3 December 2019. Retrieved 18 August 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.learner.org&rft.atitle=Rediscovering+Biology+%E2%80%93+Online+Textbook%3A+Unit+13+Genetically+Modified+Organisms&rft_id=https%3A%2F%2Fwww.learner.org%2Fcourses%2Fbiology%2Ftextbook%2Fgmo%2Fgmo_2.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:3-113">^ <a href="#cite_ref-:3_113-0">a</a> <a href="#cite_ref-:3_113-1">b</a> <a href="#cite_ref-:3_113-2">c</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAlbertsJohnsonLewisRaff2002" class="citation book cs1">Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2002). "Studying Gene Expression and Function". <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/books/NBK26818/">Molecular Biology of the Cell</a> (4th ed.). New York: Garland Science. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-8153-3218-1" title="Special:BookSources/0-8153-3218-1"><bdi>0-8153-3218-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Studying+Gene+Expression+and+Function&rft.btitle=Molecular+Biology+of+the+Cell&rft.place=New+York&rft.edition=4th&rft.pub=Garland+Science&rft.date=2002&rft.isbn=0-8153-3218-1&rft.aulast=Alberts&rft.aufirst=Bruce&rft.au=Johnson%2C+Alexander&rft.au=Lewis%2C+Julian&rft.au=Raff%2C+Martin&rft.au=Roberts%2C+Keith&rft.au=Walter%2C+Peter&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fbooks%2FNBK26818%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-114"><a href="#cite_ref-114">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFParkCochran2009" class="citation book cs1">Park SJ, Cochran JR (25 September 2009). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=ycVoWFqDTmAC&pg=PA94">Protein Engineering and Design</a>. CRC Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4200-7659-2" title="Special:BookSources/978-1-4200-7659-2"><bdi>978-1-4200-7659-2</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Protein+Engineering+and+Design&rft.pub=CRC+Press&rft.date=2009-09-25&rft.isbn=978-1-4200-7659-2&rft.aulast=Park&rft.aufirst=Sheldon+J.&rft.au=Cochran%2C+Jennifer+R.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DycVoWFqDTmAC%26pg%3DPA94&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-115"><a href="#cite_ref-115">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKurnaz2015" class="citation book cs1">Kurnaz IA (8 May 2015). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=ed4_CQAAQBAJ&pg=PA114">Techniques in Genetic Engineering</a>. CRC Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4822-6090-8" title="Special:BookSources/978-1-4822-6090-8"><bdi>978-1-4822-6090-8</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Techniques+in+Genetic+Engineering&rft.pub=CRC+Press&rft.date=2015-05-08&rft.isbn=978-1-4822-6090-8&rft.aulast=Kurnaz&rft.aufirst=Isil+Aksan&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3Ded4_CQAAQBAJ%26pg%3DPA114&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-116"><a href="#cite_ref-116">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20110714085807/http://www.microbiologyprocedure.com/microbial-genetics/applications-of-genetic-engineering.htm">"Applications of Genetic Engineering"</a>. Microbiologyprocedure. Archived from <a rel="nofollow" class="external text" href="http://www.microbiologyprocedure.com/microbial-genetics/applications-of-genetic-engineering.htm">the original</a> on 14 July 2011. Retrieved 9 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Applications+of+Genetic+Engineering&rft.pub=Microbiologyprocedure&rft_id=http%3A%2F%2Fwww.microbiologyprocedure.com%2Fmicrobial-genetics%2Fapplications-of-genetic-engineering.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-117"><a href="#cite_ref-117">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20100527060202/http://www.easyscience.co.nz/ubbiology/biotech/lesson4.htm">"Biotech: What are transgenic organisms?"</a>. Easyscience. 2002. Archived from <a rel="nofollow" class="external text" href="http://www.easyscience.co.nz/ubbiology/biotech/lesson4.htm">the original</a> on 27 May 2010. Retrieved 9 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Biotech%3A+What+are+transgenic+organisms%3F&rft.pub=Easyscience&rft.date=2002&rft_id=http%3A%2F%2Fwww.easyscience.co.nz%2Fubbiology%2Fbiotech%2Flesson4.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-118"><a href="#cite_ref-118">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSavage2007" class="citation magazine cs1">Savage N (1 August 2007). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20200409015344/https://www.technologyreview.com/biztech/19128/">"Making Gasoline from Bacteria: A biotech startup wants to coax fuels from engineered microbes"</a>. <a href="/wiki/MIT_Technology_Review" title="MIT Technology Review">MIT Technology Review</a>. Archived from <a rel="nofollow" class="external text" href="http://www.technologyreview.com/biztech/19128/">the original</a> on 9 April 2020. Retrieved 16 July 2015.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=MIT+Technology+Review&rft.atitle=Making+Gasoline+from+Bacteria%3A+A+biotech+startup+wants+to+coax+fuels+from+engineered+microbes&rft.date=2007-08-01&rft.aulast=Savage&rft.aufirst=Neil&rft_id=http%3A%2F%2Fwww.technologyreview.com%2Fbiztech%2F19128%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-119"><a href="#cite_ref-119">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSummers2013" class="citation web cs1">Summers R (24 April 2013). <a rel="nofollow" class="external text" href="https://www.newscientist.com/article/dn23431-bacteria-churn-out-first-ever-petrollike-biofuel.html">"Bacteria churn out first ever petrol-like biofuel"</a>. New Scientist. Retrieved 27 April 2013.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=New+Scientist&rft.atitle=Bacteria+churn+out+first+ever+petrol-like+biofuel&rft.date=2013-04-24&rft.aulast=Summers&rft.aufirst=Rebecca&rft_id=https%3A%2F%2Fwww.newscientist.com%2Farticle%2Fdn23431-bacteria-churn-out-first-ever-petrollike-biofuel.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-120"><a href="#cite_ref-120">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20101127053814/http://molecular-plant-biotechnology.info/use-of-microbes-in-industry-and-agriculture/applications-of-genetically-engineered-bacteria.htm">"Applications of Some Genetically Engineered Bacteria"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.molecular-plant-biotechnology.info/use-of-microbes-in-industry-and-agriculture/applications-of-genetically-engineered-bacteria.htm">the original</a> on 27 November 2010. Retrieved 9 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Applications+of+Some+Genetically+Engineered+Bacteria&rft_id=http%3A%2F%2Fwww.molecular-plant-biotechnology.info%2Fuse-of-microbes-in-industry-and-agriculture%2Fapplications-of-genetically-engineered-bacteria.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-121"><a href="#cite_ref-121">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSanderson2012" class="citation web cs1">Sanderson K (24 February 2012). <a rel="nofollow" class="external text" href="http://cen.acs.org/articles/90/web/2012/02/New-Portable-Kit-Detects-Arsenic.html">"New Portable Kit Detects Arsenic in Wells"</a>. Chemical and Engineering News. Retrieved 23 January 2013.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Chemical+and+Engineering+News&rft.atitle=New+Portable+Kit+Detects+Arsenic+in+Wells&rft.date=2012-02-24&rft.aulast=Sanderson&rft.aufirst=Katherine&rft_id=http%3A%2F%2Fcen.acs.org%2Farticles%2F90%2Fweb%2F2012%2F02%2FNew-Portable-Kit-Detects-Arsenic.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-122"><a href="#cite_ref-122">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFReeceUrryCainWasserman2011" class="citation book cs1">Reece JB, Urry LA, Cain ML, Wasserman SA, Minorsky PV, Jackson RB (2011). <a rel="nofollow" class="external text" href="https://archive.org/details/campbellbiologyj00reec/page/421">Campbell Biology Ninth Edition</a>. San Francisco: Pearson Benjamin Cummings. p. <a rel="nofollow" class="external text" href="https://archive.org/details/campbellbiologyj00reec/page/421">421</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-321-55823-7" title="Special:BookSources/978-0-321-55823-7"><bdi>978-0-321-55823-7</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Campbell+Biology+Ninth+Edition&rft.place=San+Francisco&rft.pages=421&rft.pub=Pearson+Benjamin+Cummings&rft.date=2011&rft.isbn=978-0-321-55823-7&rft.aulast=Reece&rft.aufirst=Jane+B.&rft.au=Urry%2C+Lisa+A.&rft.au=Cain%2C+Michael+L.&rft.au=Wasserman%2C+Steven+A.&rft.au=Minorsky%2C+Peter+V.&rft.au=Jackson%2C+Robert+B.&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fcampbellbiologyj00reec%2Fpage%2F421&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-123"><a href="#cite_ref-123">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://web.mit.edu/newsoffice/2009/virus-battery-0402.html">"New virus-built battery could power cars, electronic devices"</a>. Web.mit.edu. 2 April 2009. Retrieved 17 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=New+virus-built+battery+could+power+cars%2C+electronic+devices&rft.pub=Web.mit.edu&rft.date=2009-04-02&rft_id=http%3A%2F%2Fweb.mit.edu%2Fnewsoffice%2F2009%2Fvirus-battery-0402.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-124"><a href="#cite_ref-124">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation news cs1"><a rel="nofollow" class="external text" href="https://www.npr.org/templates/story/story.php?storyId=102647672">"Hidden Ingredient in New, Greener Battery: A Virus"</a>. Npr.org. Retrieved 17 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Npr.org&rft.atitle=Hidden+Ingredient+in+New%2C+Greener+Battery%3A+A+Virus&rft_id=https%3A%2F%2Fwww.npr.org%2Ftemplates%2Fstory%2Fstory.php%3FstoryId%3D102647672&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-125"><a href="#cite_ref-125">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.sciencedaily.com/releases/2010/01/100120131157.htm">"Researchers Synchronize Blinking 'Genetic Clocks' – Genetically Engineered Bacteria That Keep Track of Time"</a>. ScienceDaily. 24 January 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=ScienceDaily&rft.atitle=Researchers+Synchronize+Blinking+%27Genetic+Clocks%27+%E2%80%93+Genetically+Engineered+Bacteria+That+Keep+Track+of+Time&rft.date=2010-01-24&rft_id=https%3A%2F%2Fwww.sciencedaily.com%2Freleases%2F2010%2F01%2F100120131157.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-126"><a href="#cite_ref-126">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSuszkiw1999" class="citation web cs1">Suszkiw J (November 1999). <a rel="nofollow" class="external text" href="https://ars.usda.gov/is/ar/archive/nov99/pest1199.htm">"Tifton, Georgia: A Peanut Pest Showdown"</a>. <a href="/wiki/Agricultural_Research_Service" title="Agricultural Research Service">Agricultural Research</a>. Retrieved 23 November 2008.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Agricultural+Research&rft.atitle=Tifton%2C+Georgia%3A+A+Peanut+Pest+Showdown&rft.date=1999-11&rft.aulast=Suszkiw&rft.aufirst=Jan&rft_id=http%3A%2F%2Fars.usda.gov%2Fis%2Far%2Farchive%2Fnov99%2Fpest1199.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-127"><a href="#cite_ref-127">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMagaña-Gómezde_la_Barca2009" class="citation journal cs1">Magaña-Gómez JA, de la Barca AM (January 2009). <a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1753-4887.2008.00130.x">"Risk assessment of genetically modified crops for nutrition and health"</a>. Nutrition Reviews. 67 (1): 1–16. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1753-4887.2008.00130.x">10.1111/j.1753-4887.2008.00130.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19146501">19146501</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nutrition+Reviews&rft.atitle=Risk+assessment+of+genetically+modified+crops+for+nutrition+and+health&rft.volume=67&rft.issue=1&rft.pages=1-16&rft.date=2009-01&rft_id=info%3Adoi%2F10.1111%2Fj.1753-4887.2008.00130.x&rft_id=info%3Apmid%2F19146501&rft.aulast=Maga%C3%B1a-G%C3%B3mez&rft.aufirst=JA&rft.au=de+la+Barca%2C+AM&rft_id=https%3A%2F%2Fdoi.org%2F10.1111%252Fj.1753-4887.2008.00130.x&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-128"><a href="#cite_ref-128">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFIslam2008" class="citation journal cs1">Islam A (2008). <a rel="nofollow" class="external text" href="https://doi.org/10.3329%2Fptcb.v16i2.1113">"Fungus Resistant Transgenic Plants: Strategies, Progress and Lessons Learnt"</a>. Plant Tissue Culture and Biotechnology. 16 (2): 117–38. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3329%2Fptcb.v16i2.1113">10.3329/ptcb.v16i2.1113</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Plant+Tissue+Culture+and+Biotechnology&rft.atitle=Fungus+Resistant+Transgenic+Plants%3A+Strategies%2C+Progress+and+Lessons+Learnt&rft.volume=16&rft.issue=2&rft.pages=117-38&rft.date=2008&rft_id=info%3Adoi%2F10.3329%2Fptcb.v16i2.1113&rft.aulast=Islam&rft.aufirst=Aparna&rft_id=https%3A%2F%2Fdoi.org%2F10.3329%252Fptcb.v16i2.1113&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-129"><a href="#cite_ref-129">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20100603215011/http://www.gmo-compass.org/eng/agri_biotechnology/breeding_aims/148.disease_resistant_crops.html">"Disease resistant crops"</a>. GMO Compass. Archived from <a rel="nofollow" class="external text" href="http://www.gmo-compass.org/eng/agri_biotechnology/breeding_aims/148.disease_resistant_crops.html">the original</a> on 3 June 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Disease+resistant+crops&rft.pub=GMO+Compass&rft_id=http%3A%2F%2Fwww.gmo-compass.org%2Feng%2Fagri_biotechnology%2Fbreeding_aims%2F148.disease_resistant_crops.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-130"><a href="#cite_ref-130">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDemontTollens2004" class="citation journal cs1">Demont M, Tollens E (2004). "First impact of biotechnology in the EU: Bt maize adoption in Spain". Annals of Applied Biology. 145 (2): 197–207. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1744-7348.2004.tb00376.x">10.1111/j.1744-7348.2004.tb00376.x</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Annals+of+Applied+Biology&rft.atitle=First+impact+of+biotechnology+in+the+EU%3A+Bt+maize+adoption+in+Spain&rft.volume=145&rft.issue=2&rft.pages=197-207&rft.date=2004&rft_id=info%3Adoi%2F10.1111%2Fj.1744-7348.2004.tb00376.x&rft.aulast=Demont&rft.aufirst=M&rft.au=Tollens%2C+E&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Biodiversity-131"><a href="#cite_ref-Biodiversity_131-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChivianBernstein2008" class="citation book cs1">Chivian E, Bernstein A (2008). <a rel="nofollow" class="external text" href="https://archive.org/details/sustaininglifeho00eric">Sustaining Life</a>. Oxford University Press, Inc. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-19-517509-7" title="Special:BookSources/978-0-19-517509-7"><bdi>978-0-19-517509-7</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Sustaining+Life&rft.pub=Oxford+University+Press%2C+Inc&rft.date=2008&rft.isbn=978-0-19-517509-7&rft.aulast=Chivian&rft.aufirst=Eric&rft.au=Bernstein%2C+Aaron&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsustaininglifeho00eric&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Deborah_B._Whitman_2000-132">^ <a href="#cite_ref-Deborah_B._Whitman_2000_132-0">a</a> <a href="#cite_ref-Deborah_B._Whitman_2000_132-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWhitman2000" class="citation web cs1">Whitman DB (2000). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20150216145707/http://www.csa.com/discoveryguides/gmfood/overview.php">"Genetically Modified Foods: Harmful or Helpful?"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.csa.com/discoveryguides/gmfood/overview.php">the original</a> on 16 February 2015. Retrieved 9 July 2010.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Genetically+Modified+Foods%3A+Harmful+or+Helpful%3F&rft.date=2000&rft.aulast=Whitman&rft.aufirst=Deborah+B.&rft_id=http%3A%2F%2Fwww.csa.com%2Fdiscoveryguides%2Fgmfood%2Foverview.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Genetically_Engineered_Salmon-133"><a href="#cite_ref-Genetically_Engineered_Salmon_133-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPollack2015" class="citation news cs1">Pollack A (19 November 2015). <a rel="nofollow" class="external text" href="https://www.nytimes.com/2015/11/20/business/genetically-engineered-salmon-approved-for-consumption.html?_r=0">"Genetically Engineered Salmon Approved for Consumption"</a>. The New York Times. Retrieved 21 April 2016.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+York+Times&rft.atitle=Genetically+Engineered+Salmon+Approved+for+Consumption&rft.date=2015-11-19&rft.aulast=Pollack&rft.aufirst=Andrew&rft_id=https%3A%2F%2Fwww.nytimes.com%2F2015%2F11%2F20%2Fbusiness%2Fgenetically-engineered-salmon-approved-for-consumption.html%3F_r%3D0&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-134"><a href="#cite_ref-134">^</a> Rapeseed (canola) has been genetically engineered to modify its oil content with a gene encoding a "12:0 thioesterase" (TE) enzyme from the California bay plant (<a href="/wiki/Umbellularia_californica" class="mw-redirect" title="Umbellularia californica">Umbellularia californica</a>) to increase medium length fatty acids, see: <a rel="nofollow" class="external text" href="http://www.geo-pie.cornell.edu/traits/altoil.html">Geo-pie.cornell.edu</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20090705230132/http://www.geo-pie.cornell.edu/traits/altoil.html">Archived</a> 5 July 2009 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> </li> <li id="cite_note-135"><a href="#cite_ref-135">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBomgardner2012" class="citation journal cs1">Bomgardner MM (2012). <a rel="nofollow" class="external text" href="http://cen.acs.org/articles/90/i11/Replacing-Trans-Fat.html">"Replacing Trans Fat: New crops from Dow Chemical and DuPont target food makers looking for stable, heart-healthy oils"</a>. Chemical and Engineering News. 90 (11): 30–32. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1021%2Fcen-09011-bus1">10.1021/cen-09011-bus1</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Chemical+and+Engineering+News&rft.atitle=Replacing+Trans+Fat%3A+New+crops+from+Dow+Chemical+and+DuPont+target+food+makers+looking+for+stable%2C+heart-healthy+oils&rft.volume=90&rft.issue=11&rft.pages=30-32&rft.date=2012&rft_id=info%3Adoi%2F10.1021%2Fcen-09011-bus1&rft.aulast=Bomgardner&rft.aufirst=MM&rft_id=http%3A%2F%2Fcen.acs.org%2Farticles%2F90%2Fi11%2FReplacing-Trans-Fat.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-136"><a href="#cite_ref-136">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKramerRedenbaugh1994" class="citation journal cs1">Kramer MG, Redenbaugh K (1 January 1994). "Commercialization of a tomato with an antisense polygalacturonase gene: The FLAVR SAVR™ tomato story". Euphytica. 79 (3): 293–97. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2FBF00022530">10.1007/BF00022530</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0014-2336">0014-2336</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:45071333">45071333</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Euphytica&rft.atitle=Commercialization+of+a+tomato+with+an+antisense+polygalacturonase+gene%3A+The+FLAVR+SAVR%E2%84%A2+tomato+story&rft.volume=79&rft.issue=3&rft.pages=293-97&rft.date=1994-01-01&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A45071333%23id-name%3DS2CID&rft.issn=0014-2336&rft_id=info%3Adoi%2F10.1007%2FBF00022530&rft.aulast=Kramer&rft.aufirst=Matthew+G.&rft.au=Redenbaugh%2C+Keith&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-137"><a href="#cite_ref-137">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMarvier2008" class="citation journal cs1">Marvier M (2008). <a rel="nofollow" class="external text" href="https://hal.archives-ouvertes.fr/hal-00886450/file/hal-00886450.pdf">"Pharmaceutical crops in California, benefits and risks. A review"</a> (PDF). Agronomy for Sustainable Development. 28 (1): 1–9. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2008AgSD...28....1M">2008AgSD...28....1M</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1051%2Fagro%3A2007050">10.1051/agro:2007050</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:29538486">29538486</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20180719040330/https://hal.archives-ouvertes.fr/hal-00886450/file/hal-00886450.pdf">Archived</a> (PDF) from the original on 19 July 2018.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Agronomy+for+Sustainable+Development&rft.atitle=Pharmaceutical+crops+in+California%2C+benefits+and+risks.+A+review&rft.volume=28&rft.issue=1&rft.pages=1-9&rft.date=2008&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A29538486%23id-name%3DS2CID&rft_id=info%3Adoi%2F10.1051%2Fagro%3A2007050&rft_id=info%3Abibcode%2F2008AgSD...28....1M&rft.aulast=Marvier&rft.aufirst=Michelle&rft_id=https%3A%2F%2Fhal.archives-ouvertes.fr%2Fhal-00886450%2Ffile%2Fhal-00886450.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-138"><a href="#cite_ref-138">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.fda.gov/AnimalVeterinary/NewsEvents/FDAVeterinarianNewsletter/ucm190728.htm">"FDA Approves First Human Biologic Produced by GE Animals"</a>. US Food and Drug Administration.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=FDA+Approves+First+Human+Biologic+Produced+by+GE+Animals&rft.pub=US+Food+and+Drug+Administration&rft_id=https%3A%2F%2Fwww.fda.gov%2FAnimalVeterinary%2FNewsEvents%2FFDAVeterinarianNewsletter%2Fucm190728.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-139"><a href="#cite_ref-139">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRebêlo2004" class="citation web cs1">Rebêlo P (15 July 2004). <a rel="nofollow" class="external text" href="http://www.scidev.net/en/news/gm-cow-milk-could-provide-treatment-for-blood-dis.html">"GM cow milk 'could provide treatment for blood disease'"</a>. SciDev.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=GM+cow+milk+%27could+provide+treatment+for+blood+disease%27&rft.pub=SciDev&rft.date=2004-07-15&rft.aulast=Reb%C3%AAlo&rft.aufirst=Paulo&rft_id=http%3A%2F%2Fwww.scidev.net%2Fen%2Fnews%2Fgm-cow-milk-could-provide-treatment-for-blood-dis.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-140"><a href="#cite_ref-140">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAnguloCooke2002" class="citation journal cs1">Angulo E, Cooke B (December 2002). "First synthesize new viruses then regulate their release? The case of the wild rabbit". Molecular Ecology. 11 (12): 2703–9. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2002MolEc..11.2703A">2002MolEc..11.2703A</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1046%2Fj.1365-294X.2002.01635.x">10.1046/j.1365-294X.2002.01635.x</a>. <a href="/wiki/Hdl_(identifier)" class="mw-redirect" title="Hdl (identifier)">hdl</a>:<a rel="nofollow" class="external text" href="https://hdl.handle.net/10261%2F45541">10261/45541</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12453252">12453252</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:23916432">23916432</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Molecular+Ecology&rft.atitle=First+synthesize+new+viruses+then+regulate+their+release%3F+The+case+of+the+wild+rabbit&rft.volume=11&rft.issue=12&rft.pages=2703-9&rft.date=2002-12&rft_id=info%3Ahdl%2F10261%2F45541&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A23916432%23id-name%3DS2CID&rft_id=info%3Abibcode%2F2002MolEc..11.2703A&rft_id=info%3Apmid%2F12453252&rft_id=info%3Adoi%2F10.1046%2Fj.1365-294X.2002.01635.x&rft.aulast=Angulo&rft.aufirst=E&rft.au=Cooke%2C+B&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-141"><a href="#cite_ref-141">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAdamsPiovesanStraussBrown2002" class="citation journal cs1">Adams JM, Piovesan G, Strauss S, Brown S (2 August 2002). "The Case for Genetic Engineering of Native and Landscape Trees against Introduced Pests and Diseases". Conservation Biology. 16 (4): 874–79. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2002ConBi..16..874A">2002ConBi..16..874A</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1046%2Fj.1523-1739.2002.00523.x">10.1046/j.1523-1739.2002.00523.x</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:86697592">86697592</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Conservation+Biology&rft.atitle=The+Case+for+Genetic+Engineering+of+Native+and+Landscape+Trees+against+Introduced+Pests+and+Diseases&rft.volume=16&rft.issue=4&rft.pages=874-79&rft.date=2002-08-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A86697592%23id-name%3DS2CID&rft_id=info%3Adoi%2F10.1046%2Fj.1523-1739.2002.00523.x&rft_id=info%3Abibcode%2F2002ConBi..16..874A&rft.aulast=Adams&rft.aufirst=JM&rft.au=Piovesan%2C+G&rft.au=Strauss%2C+S&rft.au=Brown%2C+S&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-142"><a href="#cite_ref-142">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFThomasRoemerDonlanDickson2013" class="citation journal cs1">Thomas MA, Roemer GW, Donlan CJ, Dickson BG, Matocq M, Malaney J (September 2013). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F501485a">"Ecology: Gene tweaking for conservation"</a>. Nature. 501 (7468): 485–6. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F501485a">10.1038/501485a</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24073449">24073449</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Ecology%3A+Gene+tweaking+for+conservation&rft.volume=501&rft.issue=7468&rft.pages=485-6&rft.date=2013-09&rft_id=info%3Adoi%2F10.1038%2F501485a&rft_id=info%3Apmid%2F24073449&rft.aulast=Thomas&rft.aufirst=MA&rft.au=Roemer%2C+GW&rft.au=Donlan%2C+CJ&rft.au=Dickson%2C+BG&rft.au=Matocq%2C+M&rft.au=Malaney%2C+J&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252F501485a&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-143"><a href="#cite_ref-143">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPasko2007" class="citation web cs1">Pasko JM (4 March 2007). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20131004234217/http://www.nbcnews.com/id/17387568/">"Bio-artists bridge gap between arts, sciences: Use of living organisms is attracting attention and controversy"</a>. msnbc. Archived from <a rel="nofollow" class="external text" href="http://www.nbcnews.com/id/17387568">the original</a> on 4 October 2013.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Bio-artists+bridge+gap+between+arts%2C+sciences%3A+Use+of+living+organisms+is+attracting+attention+and+controversy&rft.pub=msnbc&rft.date=2007-03-04&rft.aulast=Pasko&rft.aufirst=Jessica+M.&rft_id=http%3A%2F%2Fwww.nbcnews.com%2Fid%2F17387568&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-144"><a href="#cite_ref-144">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJackson2005" class="citation web cs1">Jackson J (6 December 2005). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20051216101532/http://news.nationalgeographic.com/news/2005/12/1206_051206_bacteria_photos.html">"Genetically Modified Bacteria Produce Living Photographs"</a>. National Geographic News. Archived from <a rel="nofollow" class="external text" href="http://news.nationalgeographic.com/news/2005/12/1206_051206_bacteria_photos.html">the original</a> on 16 December 2005.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Genetically+Modified+Bacteria+Produce+Living+Photographs&rft.pub=National+Geographic+News&rft.date=2005-12-06&rft.aulast=Jackson&rft.aufirst=Joab&rft_id=http%3A%2F%2Fnews.nationalgeographic.com%2Fnews%2F2005%2F12%2F1206_051206_bacteria_photos.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-physorg-145"><a href="#cite_ref-physorg_145-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://phys.org/news/2005-04-gene-results-world-blue-rose.html">"Plant gene replacement results in the world's only blue rose"</a>. phys.org. Retrieved 30 March 2023.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=phys.org&rft.atitle=Plant+gene+replacement+results+in+the+world%27s+only+blue+rose&rft_id=https%3A%2F%2Fphys.org%2Fnews%2F2005-04-gene-results-world-blue-rose.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-146"><a href="#cite_ref-146">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKatsumotoFukuchi-MizutaniFukuiBrugliera2007" class="citation journal cs1">Katsumoto Y, Fukuchi-Mizutani M, Fukui Y, Brugliera F, Holton TA, Karan M, Nakamura N, Yonekura-Sakakibara K, Togami J, Pigeaire A, Tao GQ, Nehra NS, Lu CY, Dyson BK, Tsuda S, Ashikari T, Kusumi T, Mason JG, Tanaka Y (November 2007). "Engineering of the rose flavonoid biosynthetic pathway successfully generated blue-hued flowers accumulating delphinidin". Plant & Cell Physiology. 48 (11): 1589–600. <a href="/wiki/CiteSeerX_(identifier)" class="mw-redirect" title="CiteSeerX (identifier)">CiteSeerX</a> <a rel="nofollow" class="external text" href="https://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.319.8365">10.1.1.319.8365</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fpcp%2Fpcm131">10.1093/pcp/pcm131</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17925311">17925311</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Plant+%26+Cell+Physiology&rft.atitle=Engineering+of+the+rose+flavonoid+biosynthetic+pathway+successfully+generated+blue-hued+flowers+accumulating+delphinidin&rft.volume=48&rft.issue=11&rft.pages=1589-600&rft.date=2007-11&rft_id=https%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fsummary%3Fdoi%3D10.1.1.319.8365%23id-name%3DCiteSeerX&rft_id=info%3Apmid%2F17925311&rft_id=info%3Adoi%2F10.1093%2Fpcp%2Fpcm131&rft.aulast=Katsumoto&rft.aufirst=Y&rft.au=Fukuchi-Mizutani%2C+M&rft.au=Fukui%2C+Y&rft.au=Brugliera%2C+F&rft.au=Holton%2C+TA&rft.au=Karan%2C+M&rft.au=Nakamura%2C+N&rft.au=Yonekura-Sakakibara%2C+K&rft.au=Togami%2C+J&rft.au=Pigeaire%2C+A&rft.au=Tao%2C+GQ&rft.au=Nehra%2C+NS&rft.au=Lu%2C+CY&rft.au=Dyson%2C+BK&rft.au=Tsuda%2C+S&rft.au=Ashikari%2C+T&rft.au=Kusumi%2C+T&rft.au=Mason%2C+JG&rft.au=Tanaka%2C+Y&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-147"><a href="#cite_ref-147">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2000049150">"WIPO - Search International and National Patent Collections"</a>. patentscope.wipo.int. Retrieved 30 March 2023.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=patentscope.wipo.int&rft.atitle=WIPO+-+Search+International+and+National+Patent+Collections&rft_id=https%3A%2F%2Fpatentscope.wipo.int%2Fsearch%2Fen%2Fdetail.jsf%3FdocId%3DWO2000049150&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-148"><a href="#cite_ref-148">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFStewart2006" class="citation journal cs1">Stewart CN (April 2006). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20100703194009/http://plantsciences.utk.edu/pdf/stewart-TIBTECH-FPs-2006.pdf">"Go with the glow: fluorescent proteins to light transgenic organisms"</a> (PDF). Trends in Biotechnology. 24 (4): 155–62. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.tibtech.2006.02.002">10.1016/j.tibtech.2006.02.002</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16488034">16488034</a>. Archived from <a rel="nofollow" class="external text" href="http://plantsciences.utk.edu/pdf/stewart-TIBTECH-FPs-2006.pdf">the original</a> (PDF) on 3 July 2010. Retrieved 25 October 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Trends+in+Biotechnology&rft.atitle=Go+with+the+glow%3A+fluorescent+proteins+to+light+transgenic+organisms&rft.volume=24&rft.issue=4&rft.pages=155-62&rft.date=2006-04&rft_id=info%3Adoi%2F10.1016%2Fj.tibtech.2006.02.002&rft_id=info%3Apmid%2F16488034&rft.aulast=Stewart&rft.aufirst=CN&rft_id=http%3A%2F%2Fplantsciences.utk.edu%2Fpdf%2Fstewart-TIBTECH-FPs-2006.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-149"><a href="#cite_ref-149">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBergBaltimoreBoyerCohen1974" class="citation journal cs1">Berg P, Baltimore D, Boyer HW, Cohen SN, Davis RW, Hogness DS, Nathans D, Roblin R, Watson JD, Weissman S, Zinder ND (July 1974). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110812073943/http://beck2.med.harvard.edu/week13/The%20Science%20Letter.pdf">"Letter: Potential biohazards of recombinant DNA molecules"</a> (PDF). Science. 185 (4148): 303. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1974Sci...185..303B">1974Sci...185..303B</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1126%2Fscience.185.4148.303">10.1126/science.185.4148.303</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC388511">388511</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/4600381">4600381</a>. Archived from <a rel="nofollow" class="external text" href="http://beck2.med.harvard.edu/week13/The%20Science%20Letter.pdf">the original</a> (PDF) on 12 August 2011. Retrieved 3 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science&rft.atitle=Letter%3A+Potential+biohazards+of+recombinant+DNA+molecules&rft.volume=185&rft.issue=4148&rft.pages=303&rft.date=1974-07&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC388511%23id-name%3DPMC&rft_id=info%3Apmid%2F4600381&rft_id=info%3Adoi%2F10.1126%2Fscience.185.4148.303&rft_id=info%3Abibcode%2F1974Sci...185..303B&rft.aulast=Berg&rft.aufirst=P&rft.au=Baltimore%2C+D&rft.au=Boyer%2C+HW&rft.au=Cohen%2C+SN&rft.au=Davis%2C+RW&rft.au=Hogness%2C+DS&rft.au=Nathans%2C+D&rft.au=Roblin%2C+R&rft.au=Watson%2C+JD&rft.au=Weissman%2C+S&rft.au=Zinder%2C+ND&rft_id=http%3A%2F%2Fbeck2.med.harvard.edu%2Fweek13%2FThe%2520Science%2520Letter.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-McHughen2007-150"><a href="#cite_ref-McHughen2007_150-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMcHughenSmyth2008" class="citation journal cs1">McHughen A, Smyth S (January 2008). <a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1467-7652.2007.00300.x">"US regulatory system for genetically modified [genetically modified organism (GMO), rDNA or transgenic] crop cultivars"</a>. Plant Biotechnology Journal. 6 (1): 2–12. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1467-7652.2007.00300.x">10.1111/j.1467-7652.2007.00300.x</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17956539">17956539</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Plant+Biotechnology+Journal&rft.atitle=US+regulatory+system+for+genetically+modified+%5Bgenetically+modified+organism+%28GMO%29%2C+rDNA+or+transgenic%5D+crop+cultivars&rft.volume=6&rft.issue=1&rft.pages=2-12&rft.date=2008-01&rft_id=info%3Adoi%2F10.1111%2Fj.1467-7652.2007.00300.x&rft_id=info%3Apmid%2F17956539&rft.aulast=McHughen&rft.aufirst=A&rft.au=Smyth%2C+S&rft_id=https%3A%2F%2Fdoi.org%2F10.1111%252Fj.1467-7652.2007.00300.x&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:7-151">^ <a href="#cite_ref-:7_151-0">a</a> <a href="#cite_ref-:7_151-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFU.S._Office_of_Science_and_Technology_Policy1986" class="citation journal cs1">U.S. Office of Science and Technology Policy (June 1986). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110516173328/http://usbiotechreg.nbii.gov/CoordinatedFrameworkForRegulationOfBiotechnology1986.pdf">"Coordinated framework for regulation of biotechnology; announcement of policy; notice for public comment"</a> (PDF). Federal Register. 51 (123): 23302–23350. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11655807">11655807</a>. Archived from <a rel="nofollow" class="external text" href="http://usbiotechreg.nbii.gov/CoordinatedFrameworkForRegulationOfBiotechnology1986.pdf">the original</a> (PDF) on 16 May 2011.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Federal+Register&rft.atitle=Coordinated+framework+for+regulation+of+biotechnology%3B+announcement+of+policy%3B+notice+for+public+comment&rft.volume=51&rft.issue=123&rft.pages=23302-23350&rft.date=1986-06&rft_id=info%3Apmid%2F11655807&rft.au=U.S.+Office+of+Science+and+Technology+Policy&rft_id=http%3A%2F%2Fusbiotechreg.nbii.gov%2FCoordinatedFrameworkForRegulationOfBiotechnology1986.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> <code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: <code class="cs1-code">|author1=</code> has generic name (<a href="/wiki/Help:CS1_errors#generic_name" title="Help:CS1 errors">help</a>) </li> <li id="cite_note-152"><a href="#cite_ref-152">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRedick,_T.P.2007" class="citation journal cs1">Redick, T.P. (2007). "The Cartagena Protocol on biosafety: Precautionary priority in biotech crop approvals and containment of commodities shipments, 2007". Colorado Journal of International Environmental Law and Policy. 18: 51–116.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Colorado+Journal+of+International+Environmental+Law+and+Policy&rft.atitle=The+Cartagena+Protocol+on+biosafety%3A+Precautionary+priority+in+biotech+crop+approvals+and+containment+of+commodities+shipments%2C+2007&rft.volume=18&rft.pages=51-116&rft.date=2007&rft.au=Redick%2C+T.P.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-153"><a href="#cite_ref-153">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://bch.cbd.int/protocol/background/">"About the Protocol"</a>. The Biosafety Clearing-House (BCH). 29 May 2012.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=The+Biosafety+Clearing-House+%28BCH%29&rft.atitle=About+the+Protocol&rft.date=2012-05-29&rft_id=http%3A%2F%2Fbch.cbd.int%2Fprotocol%2Fbackground%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Kimani-154"><a href="#cite_ref-Kimani_154-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20160304190534/http://www.agbioforum.org/v13n3/v13n3a02-gruere.htm#R13">"AgBioForum 13(3): Implications of Import Regulations and Information Requirements under the Cartagena Protocol on Biosafety for GM Commodities in Kenya"</a>. 28 October 2010. Archived from <a rel="nofollow" class="external text" href="http://www.agbioforum.org/v13n3/v13n3a02-gruere.htm#R13">the original</a> on 4 March 2016. Retrieved 3 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=AgBioForum+13%283%29%3A+Implications+of+Import+Regulations+and+Information+Requirements+under+the+Cartagena+Protocol+on+Biosafety+for+GM+Commodities+in+Kenya&rft.date=2010-10-28&rft_id=http%3A%2F%2Fwww.agbioforum.org%2Fv13n3%2Fv13n3a02-gruere.htm%23R13&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-155"><a href="#cite_ref-155">^</a> <a rel="nofollow" class="external text" href="https://tile.loc.gov/storage-services/service/ll/llglrd/2014427358/2014427358.pdf">Restrictions on Genetically Modified Organisms.</a> Library of Congress, March 2014 (LL File No. 2013-009894). Summary about a number of countries. <a rel="nofollow" class="external text" href="https://www.loc.gov/item/2014427358/">via</a> </li> <li id="cite_note-156"><a href="#cite_ref-156">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBashshur2013" class="citation web cs1">Bashshur R (February 2013). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20160929163558/http://www.americanbar.org/content/newsletter/publications/aba_health_esource_home/aba_health_law_esource_1302_bashshur.html">"FDA and Regulation of GMOs"</a>. American Bar Association. Archived from <a rel="nofollow" class="external text" href="http://www.americanbar.org/content/newsletter/publications/aba_health_esource_home/aba_health_law_esource_1302_bashshur.html">the original</a> on 29 September 2016. Retrieved 24 February 2016.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=FDA+and+Regulation+of+GMOs&rft.pub=American+Bar+Association&rft.date=2013-02&rft.aulast=Bashshur&rft.aufirst=Ramona&rft_id=http%3A%2F%2Fwww.americanbar.org%2Fcontent%2Fnewsletter%2Fpublications%2Faba_health_esource_home%2Faba_health_law_esource_1302_bashshur.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-157"><a href="#cite_ref-157">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSifferlin2015" class="citation magazine cs1">Sifferlin A (3 October 2015). <a rel="nofollow" class="external text" href="https://time.com/4060476/eu-gmo-crops-european-union-opt-out/">"Over Half of E.U. Countries Are Opting Out of GMOs"</a>. Time.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Time&rft.atitle=Over+Half+of+E.U.+Countries+Are+Opting+Out+of+GMOs&rft.date=2015-10-03&rft.aulast=Sifferlin&rft.aufirst=Alexandra&rft_id=https%3A%2F%2Ftime.com%2F4060476%2Feu-gmo-crops-european-union-opt-out%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-158"><a href="#cite_ref-158">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLynchVogel2001" class="citation web cs1">Lynch D, Vogel D (5 April 2001). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20160929200540/http://www.cfr.org/agricultural-policy/regulation-gmos-europe-united-states-case-study-contemporary-european-regulatory-politics/p8688">"The Regulation of GMOs in Europe and the United States: A Case-Study of Contemporary European Regulatory Politics"</a>. Council on Foreign Relations. Archived from <a rel="nofollow" class="external text" href="http://www.cfr.org/agricultural-policy/regulation-gmos-europe-united-states-case-study-contemporary-european-regulatory-politics/p8688">the original</a> on 29 September 2016. Retrieved 24 February 2016.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=The+Regulation+of+GMOs+in+Europe+and+the+United+States%3A+A+Case-Study+of+Contemporary+European+Regulatory+Politics&rft.pub=Council+on+Foreign+Relations&rft.date=2001-04-05&rft.aulast=Lynch&rft.aufirst=Diahanna&rft.au=Vogel%2C+David&rft_id=http%3A%2F%2Fwww.cfr.org%2Fagricultural-policy%2Fregulation-gmos-europe-united-states-case-study-contemporary-european-regulatory-politics%2Fp8688&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-159"><a href="#cite_ref-159">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.loc.gov/law/help/restrictions-on-gmos/">"Restrictions on Genetically Modified Organisms - Law Library of Congress"</a>. <a href="/wiki/Library_of_Congress" title="Library of Congress">Library of Congress</a>. 22 January 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Library+of+Congress&rft.atitle=Restrictions+on+Genetically+Modified+Organisms+-+Law+Library+of+Congress&rft.date=2017-01-22&rft_id=https%3A%2F%2Fwww.loc.gov%2Flaw%2Fhelp%2Frestrictions-on-gmos%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Marsen-160"><a href="#cite_ref-Marsen_160-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMarden2003" class="citation journal cs1">Marden, Emily (1 May 2003). <a rel="nofollow" class="external text" href="https://lira.bc.edu/work/ns/d6fc0184-cdee-497d-add0-56ab2c374b25">"Risk and Regulation: U.S. Regulatory Policy on Genetically Modified Food and Agriculture"</a>. Boston College Law Review. 44 (3): 733.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Boston+College+Law+Review&rft.atitle=Risk+and+Regulation%3A+U.S.+Regulatory+Policy+on+Genetically+Modified+Food+and+Agriculture&rft.volume=44&rft.issue=3&rft.pages=733&rft.date=2003-05-01&rft.aulast=Marden&rft.aufirst=Emily&rft_id=https%3A%2F%2Flira.bc.edu%2Fwork%2Fns%2Fd6fc0184-cdee-497d-add0-56ab2c374b25&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Davison2010-161">^ <a href="#cite_ref-Davison2010_161-0">a</a> <a href="#cite_ref-Davison2010_161-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDavison2010" class="citation journal cs1">Davison J (2010). "GM plants: Science, politics and EC regulations". Plant Science. 178 (2): 94–98. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2010PlnSc.178...94D">2010PlnSc.178...94D</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.plantsci.2009.12.005">10.1016/j.plantsci.2009.12.005</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Plant+Science&rft.atitle=GM+plants%3A+Science%2C+politics+and+EC+regulations&rft.volume=178&rft.issue=2&rft.pages=94-98&rft.date=2010&rft_id=info%3Adoi%2F10.1016%2Fj.plantsci.2009.12.005&rft_id=info%3Abibcode%2F2010PlnSc.178...94D&rft.aulast=Davison&rft.aufirst=John&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:8-162">^ <a href="#cite_ref-:8_162-0">a</a> <a href="#cite_ref-:8_162-1">b</a> <a rel="nofollow" class="external text" href="http://www.gmo-compass.org/eng/regulation/regulatory_process/156.european_regulatory_system_genetic_engineering.html">GMO Compass: The European Regulatory System.</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20120814025652/http://www.gmo-compass.org/eng/regulation/regulatory_process/156.european_regulatory_system_genetic_engineering.html">Archived</a> 14 August 2012 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> Retrieved 28 July 2012. </li> <li id="cite_note-163"><a href="#cite_ref-163">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGovernment_of_Canada,_Canadian_Food_Inspection_Agency2015" class="citation web cs1">Government of Canada, Canadian Food Inspection Agency (20 March 2015). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110422171028/http://www.inspection.gc.ca/english/sci/biotech/bioteche.shtml">"Information for the general public"</a>. www.inspection.gc.ca. Archived from <a rel="nofollow" class="external text" href="http://www.inspection.gc.ca/english/sci/biotech/bioteche.shtml">the original</a> on 22 April 2011. Retrieved 3 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.inspection.gc.ca&rft.atitle=Information+for+the+general+public&rft.date=2015-03-20&rft.au=Government+of+Canada%2C+Canadian+Food+Inspection+Agency&rft_id=http%3A%2F%2Fwww.inspection.gc.ca%2Fenglish%2Fsci%2Fbiotech%2Fbioteche.shtml&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-164"><a href="#cite_ref-164">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFForsberg2013" class="citation encyclopaedia cs1">Forsberg, Cecil W. (23 April 2013). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20130918203331/http://www.thecanadianencyclopedia.com/articles/genetically-modified-foods">"Genetically Modified Foods"</a>. The Canadian Encyclopedia. Archived from <a rel="nofollow" class="external text" href="http://www.thecanadianencyclopedia.com/articles/genetically-modified-foods">the original</a> on 18 September 2013. Retrieved 4 October 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Genetically+Modified+Foods&rft.btitle=The+Canadian+Encyclopedia&rft.date=2013-04-23&rft.aulast=Forsberg&rft.aufirst=Cecil+W.&rft_id=http%3A%2F%2Fwww.thecanadianencyclopedia.com%2Farticles%2Fgenetically-modified-foods&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-165"><a href="#cite_ref-165">^</a> Evans, Brent and Lupescu, Mihai (15 July 2012) <a rel="nofollow" class="external text" href="https://gain.fas.usda.gov/Recent%20GAIN%20Publications/Agricultural%20Biotechnology%20Annual_Ottawa_Canada_07-20-2012.pdf">Canada – Agricultural Biotechnology Annual – 2012</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20131215160309/http://gain.fas.usda.gov/Recent%20GAIN%20Publications/Agricultural%20Biotechnology%20Annual_Ottawa_Canada_07-20-2012.pdf">Archived</a> 15 December 2013 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> GAIN (Global Agricultural Information Network) report CA12029, United States Department of Agriculture, Foreifn Agricultural Service, Retrieved 5 November 2012 </li> <li id="cite_note-166"><a href="#cite_ref-166">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMcHugen2000" class="citation book cs1">McHugen A (14 September 2000). <a rel="nofollow" class="external text" href="https://archive.org/details/pandoraspicnicba00mchu">"Chapter 1: Hors-d'oeuvres and entrees/What is genetic modification? What are GMOs?"</a>. Pandora's Picnic Basket. Oxford University Press. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-19-850674-4" title="Special:BookSources/978-0-19-850674-4"><bdi>978-0-19-850674-4</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Chapter+1%3A+Hors-d%27oeuvres+and+entrees%2FWhat+is+genetic+modification%3F+What+are+GMOs%3F&rft.btitle=Pandora%27s+Picnic+Basket&rft.pub=Oxford+University+Press&rft.date=2000-09-14&rft.isbn=978-0-19-850674-4&rft.aulast=McHugen&rft.aufirst=Alan&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fpandoraspicnicba00mchu&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:4-167">^ <a href="#cite_ref-:4_167-0">a</a> <a href="#cite_ref-:4_167-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation journal cs1"><a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F467633b">"Editorial: Transgenic harvest"</a>. Nature. 467 (7316): 633–634. 2010. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2010Natur.467R.633.">2010Natur.467R.633.</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F467633b">10.1038/467633b</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20930796">20930796</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Editorial%3A+Transgenic+harvest&rft.volume=467&rft.issue=7316&rft.pages=633-634&rft.date=2010&rft_id=info%3Apmid%2F20930796&rft_id=info%3Adoi%2F10.1038%2F467633b&rft_id=info%3Abibcode%2F2010Natur.467R.633.&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252F467633b&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-168"><a href="#cite_ref-168">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20160725141840/http://www.agbioforum.org/v5n4/v5n4a01-huang.htm">"AgBioForum 5(4): Agricultural Biotechnology Development and Policy in China"</a>. 5 September 2003. Archived from <a rel="nofollow" class="external text" href="http://www.agbioforum.org/v5n4/v5n4a01-huang.htm">the original</a> on 25 July 2016. Retrieved 3 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=AgBioForum+5%284%29%3A+Agricultural+Biotechnology+Development+and+Policy+in+China&rft.date=2003-09-05&rft_id=http%3A%2F%2Fwww.agbioforum.org%2Fv5n4%2Fv5n4a01-huang.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-169"><a href="#cite_ref-169">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://agritech.tnau.ac.in/bio-tech/biotech_gmcrop_gmregulation.html">"TNAU Agritech Portal :: Bio Technology"</a>. agritech.tnau.ac.in.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=agritech.tnau.ac.in&rft.atitle=TNAU+Agritech+Portal+%3A%3A+Bio+Technology&rft_id=https%3A%2F%2Fagritech.tnau.ac.in%2Fbio-tech%2Fbiotech_gmcrop_gmregulation.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-BASFppt-170">^ <a href="#cite_ref-BASFppt_170-0">a</a> <a href="#cite_ref-BASFppt_170-1">b</a> <a href="#cite_ref-BASFppt_170-2">c</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20110928104527/http://www.eurofins.com/media/11753/dcontri.pdf">"BASF presentation"</a> (PDF). Archived from <a rel="nofollow" class="external text" href="http://www.eurofins.com/media/11753/dcontri.pdf">the original</a> (PDF) on 28 September 2011.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=BASF+presentation&rft_id=http%3A%2F%2Fwww.eurofins.com%2Fmedia%2F11753%2Fdcontri.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-VIC_ag-171"><a href="#cite_ref-VIC_ag_171-0">^</a> <a rel="nofollow" class="external text" href="http://www.new.dpi.vic.gov.au/agriculture/science-and-research/biotechnology/genetically-modified-crops/federal-and-state-responsibilities">Agriculture – Department of Primary Industries</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20110329120907/http://new.dpi.vic.gov.au/agriculture/science-and-research/biotechnology/genetically-modified-crops/federal-and-state-responsibilities">Archived</a> 29 March 2011 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> </li> <li id="cite_note-OTRWebsite-172">^ <a href="#cite_ref-OTRWebsite_172-0">a</a> <a href="#cite_ref-OTRWebsite_172-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.ogtr.gov.au/">"Welcome to the Office of the Gene Technology Regulator Website"</a>. Office of the Gene Technology Regulator. Retrieved 25 March 2011.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Welcome+to+the+Office+of+the+Gene+Technology+Regulator+Website&rft.pub=Office+of+the+Gene+Technology+Regulator&rft_id=http%3A%2F%2Fwww.ogtr.gov.au%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-EC1-173"><a href="#cite_ref-EC1_173-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20140120113714/http://ec.europa.eu/food/food/animalnutrition/labelling/Reg_1829_2003_en.pdf">"Regulation (EC) No 1829/2003 of the European Parliament and of the Council of 22 September 2003 On Genetically Modified Food And Feed"</a> (PDF). Official Journal of the European Union. The European Parliament and the Council of the European Union. 2003. Archived from <a rel="nofollow" class="external text" href="http://ec.europa.eu/food/food/animalnutrition/labelling/Reg_1829_2003_en.pdf">the original</a> (PDF) on 20 January 2014. <q>The labeling should include objective information to the effect that a food or feed consists of, contains or is produced from GMOs. Clear labeling, irrespective of the detectability of DNA or protein resulting from the genetic modification in the final product, meets the demands expressed in numerous surveys by a large majority of consumers, facilitates informed choice and precludes potential misleading of consumers as regards methods of manufacture or production.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Official+Journal+of+the+European+Union&rft.atitle=Regulation+%28EC%29+No+1829%2F2003+of+the+European+Parliament+and+of+the+Council+of+22+September+2003+On+Genetically+Modified+Food+And+Feed&rft.date=2003&rft_id=http%3A%2F%2Fec.europa.eu%2Ffood%2Ffood%2Fanimalnutrition%2Flabelling%2FReg_1829_2003_en.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-EC2-174"><a href="#cite_ref-EC2_174-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX:32003R1830">"Regulation (EC) No 1830/2003 of the European Parliament and of the Council of 22 September 2003 concerning the traceability and labeling of genetically modified organisms and the traceability of food and feed products produced from genetically modified organisms and amending Directive 2001/18/EC"</a>. Official Journal L 268. The European Parliament and the Council of the European Union. 2003. pp. 24–28. <q>(3) Traceability requirements for GMOs should facilitate both the withdrawal of products where unforeseen adverse effects on human health, animal health or the environment, including ecosystems, are established, and the targeting of monitoring to examine potential effects on, in particular, the environment. Traceability should also facilitate the implementation of risk management measures in accordance with the precautionary principle. (4) Traceability requirements for food and feed produced from GMOs should be established to facilitate accurate labeling of such products.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Official+Journal+L+268&rft.atitle=Regulation+%28EC%29+No+1830%2F2003+of+the+European+Parliament+and+of+the+Council+of+22+September+2003+concerning+the+traceability+and+labeling+of+genetically+modified+organisms+and+the+traceability+of+food+and+feed+products+produced+from+genetically+modified+organisms+and+amending+Directive+2001%2F18%2FEC&rft.pages=24-28&rft.date=2003&rft_id=http%3A%2F%2Feur-lex.europa.eu%2Flegal-content%2FEN%2FALL%2F%3Furi%3DCELEX%3A32003R1830&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-AMA-175"><a href="#cite_ref-AMA_175-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20120907023039/http://www.ama-assn.org/resources/doc/csaph/a12-csaph2-bioengineeredfoods.pdf">"Report 2 of the Council on Science and Public Health: Labeling of Bioengineered Foods"</a> (PDF). American Medical Association. 2012. Archived from <a rel="nofollow" class="external text" href="http://www.ama-assn.org/resources/doc/csaph/a12-csaph2-bioengineeredfoods.pdf">the original</a> (PDF) on 7 September 2012.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Report+2+of+the+Council+on+Science+and+Public+Health%3A+Labeling+of+Bioengineered+Foods&rft.pub=American+Medical+Association&rft.date=2012&rft_id=http%3A%2F%2Fwww.ama-assn.org%2Fresources%2Fdoc%2Fcsaph%2Fa12-csaph2-bioengineeredfoods.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-AAAS-176"><a href="#cite_ref-AAAS_176-0">^</a> American Association for the Advancement of Science (AAAS), Board of Directors (2012). <a rel="nofollow" class="external text" href="http://www.aaas.org/sites/default/files/AAAS_GM_statement.pdf">Statement by the AAAS Board of Directors On Labeling of Genetically Modified Foods</a>, and associated <a rel="nofollow" class="external text" href="http://www.aaas.org/news/releases/2012/1025gm_statement.shtml">Press release: Legally Mandating GM Food Labels Could Mislead and Falsely Alarm Consumers</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20131104063411/http://www.aaas.org/news/releases/2012/1025gm_statement.shtml">Archived</a> 4 November 2013 at the <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a> </li> <li id="cite_note-Burlington-2014-177"><a href="#cite_ref-Burlington-2014_177-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHallenbeck2014" class="citation news cs1">Hallenbeck T (27 April 2014). <a rel="nofollow" class="external text" href="http://www.burlingtonfreepress.com/story/news/politics/2014/04/27/gmo-labeling-came-pass-vermont/8166519/">"How GMO labeling came to pass in Vermont"</a>. Burlington Free Press. Retrieved 28 May 2014.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Burlington+Free+Press&rft.atitle=How+GMO+labeling+came+to+pass+in+Vermont&rft.date=2014-04-27&rft.aulast=Hallenbeck&rft.aufirst=Terri&rft_id=http%3A%2F%2Fwww.burlingtonfreepress.com%2Fstory%2Fnews%2Fpolitics%2F2014%2F04%2F27%2Fgmo-labeling-came-pass-vermont%2F8166519%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-RegGMFood-178"><a href="#cite_ref-RegGMFood_178-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20170610170104/http://www.hc-sc.gc.ca/sr-sr/pubs/biotech/reg_gen_mod-eng.php">"The Regulation of Genetically Modified Foods"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.hc-sc.gc.ca/sr-sr/pubs/biotech/reg_gen_mod-eng.php">the original</a> on 10 June 2017. Retrieved 5 November 2012.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=The+Regulation+of+Genetically+Modified+Foods&rft_id=http%3A%2F%2Fwww.hc-sc.gc.ca%2Fsr-sr%2Fpubs%2Fbiotech%2Freg_gen_mod-eng.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-179"><a href="#cite_ref-179">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSheldon2002" class="citation journal cs1">Sheldon IM (1 March 2002). "Regulation of biotechnology: will we ever 'freely' trade GMOs?". European Review of Agricultural Economics. 29 (1): 155–76. <a href="/wiki/CiteSeerX_(identifier)" class="mw-redirect" title="CiteSeerX (identifier)">CiteSeerX</a> <a rel="nofollow" class="external text" href="https://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.596.7670">10.1.1.596.7670</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Ferae%2F29.1.155">10.1093/erae/29.1.155</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0165-1587">0165-1587</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=European+Review+of+Agricultural+Economics&rft.atitle=Regulation+of+biotechnology%3A+will+we+ever+%27freely%27+trade+GMOs%3F&rft.volume=29&rft.issue=1&rft.pages=155-76&rft.date=2002-03-01&rft_id=https%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fsummary%3Fdoi%3D10.1.1.596.7670%23id-name%3DCiteSeerX&rft.issn=0165-1587&rft_id=info%3Adoi%2F10.1093%2Ferae%2F29.1.155&rft.aulast=Sheldon&rft.aufirst=Ian+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-180"><a href="#cite_ref-180">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDabrock2009" class="citation journal cs1">Dabrock P (December 2009). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759421">"Playing God? Synthetic biology as a theological and ethical challenge"</a>. Systems and Synthetic Biology. 3 (1–4): 47–54. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs11693-009-9028-5">10.1007/s11693-009-9028-5</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759421">2759421</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19816799">19816799</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Systems+and+Synthetic+Biology&rft.atitle=Playing+God%3F+Synthetic+biology+as+a+theological+and+ethical+challenge&rft.volume=3&rft.issue=1%E2%80%934&rft.pages=47-54&rft.date=2009-12&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2759421%23id-name%3DPMC&rft_id=info%3Apmid%2F19816799&rft_id=info%3Adoi%2F10.1007%2Fs11693-009-9028-5&rft.aulast=Dabrock&rft.aufirst=P&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2759421&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-181"><a href="#cite_ref-181">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBrown2000" class="citation journal cs1">Brown C (October 2000). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC80518">"Patenting life: genetically altered mice an invention, court declares"</a>. CMAJ. 163 (7): 867–8. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC80518">80518</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11033718">11033718</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=CMAJ&rft.atitle=Patenting+life%3A+genetically+altered+mice+an+invention%2C+court+declares&rft.volume=163&rft.issue=7&rft.pages=867-8&rft.date=2000-10&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC80518%23id-name%3DPMC&rft_id=info%3Apmid%2F11033718&rft.aulast=Brown&rft.aufirst=C&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC80518&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-182"><a href="#cite_ref-182">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFZhou2015" class="citation news cs1">Zhou W (10 August 2015). <a rel="nofollow" class="external text" href="http://sitn.hms.harvard.edu/flash/2015/the-patent-landscape-of-genetically-modified-organisms/">"The Patent Landscape of Genetically Modified Organisms"</a>. Science in the News. Retrieved 5 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science+in+the+News&rft.atitle=The+Patent+Landscape+of+Genetically+Modified+Organisms&rft.date=2015-08-10&rft.aulast=Zhou&rft.aufirst=Wen&rft_id=http%3A%2F%2Fsitn.hms.harvard.edu%2Fflash%2F2015%2Fthe-patent-landscape-of-genetically-modified-organisms%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-183"><a href="#cite_ref-183">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPuckett2016" class="citation web cs1">Puckett L (20 April 2016). <a rel="nofollow" class="external text" href="http://www.huffingtonpost.com/teen-vogue/why-the-new-gmo-foodlabel_b_9738698.html">"Why The New GMO Food-Labeling Law Is So Controversial"</a>. Huffington Post. Retrieved 5 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Huffington+Post&rft.atitle=Why+The+New+GMO+Food-Labeling+Law+Is+So+Controversial&rft.date=2016-04-20&rft.aulast=Puckett&rft.aufirst=Lily&rft_id=http%3A%2F%2Fwww.huffingtonpost.com%2Fteen-vogue%2Fwhy-the-new-gmo-foodlabel_b_9738698.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-184"><a href="#cite_ref-184">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMiller2016" class="citation news cs1">Miller H (12 April 2016). <a rel="nofollow" class="external text" href="http://www.latimes.com/opinion/op-ed/la-oe-0412-miller-gmo-labels-unscientific-20160412-story.html">"GMO food labels are meaningless"</a>. Los Angeles Times. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0458-3035">0458-3035</a>. Retrieved 5 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Los+Angeles+Times&rft.atitle=GMO+food+labels+are+meaningless&rft.date=2016-04-12&rft.issn=0458-3035&rft.aulast=Miller&rft.aufirst=Henry&rft_id=http%3A%2F%2Fwww.latimes.com%2Fopinion%2Fop-ed%2Fla-oe-0412-miller-gmo-labels-unscientific-20160412-story.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-185"><a href="#cite_ref-185">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSavage" class="citation news cs1">Savage S. <a rel="nofollow" class="external text" href="https://www.forbes.com/sites/stevensavage/2015/06/26/who-controls-the-food-supply/#449914fe2f9d">"Who Controls The Food Supply?"</a>. Forbes. Retrieved 5 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Forbes&rft.atitle=Who+Controls+The+Food+Supply%3F&rft.aulast=Savage&rft.aufirst=Steven&rft_id=https%3A%2F%2Fwww.forbes.com%2Fsites%2Fstevensavage%2F2015%2F06%2F26%2Fwho-controls-the-food-supply%2F%23449914fe2f9d&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-186"><a href="#cite_ref-186">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKnight2016" class="citation book cs1">Knight AJ (14 April 2016). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=jGD7CwAAQBAJ&pg=PA156">Science, Risk, and Policy</a>. Routledge. p. 156. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-317-28081-1" title="Special:BookSources/978-1-317-28081-1"><bdi>978-1-317-28081-1</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Science%2C+Risk%2C+and+Policy&rft.pages=156&rft.pub=Routledge&rft.date=2016-04-14&rft.isbn=978-1-317-28081-1&rft.aulast=Knight&rft.aufirst=Andrew+J.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3DjGD7CwAAQBAJ%26pg%3DPA156&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-187"><a href="#cite_ref-187">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHakim2016" class="citation news cs1">Hakim D (29 October 2016). <a rel="nofollow" class="external text" href="https://www.nytimes.com/2016/10/30/business/gmo-promise-falls-short.html">"Doubts About the Promised Bounty of Genetically Modified Crops"</a>. The New York Times. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/0362-4331">0362-4331</a>. <a rel="nofollow" class="external text" href="https://ghostarchive.org/archive/20220102/https://www.nytimes.com/2016/10/30/business/gmo-promise-falls-short.html">Archived</a> from the original on 2 January 2022. Retrieved 5 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+York+Times&rft.atitle=Doubts+About+the+Promised+Bounty+of+Genetically+Modified+Crops&rft.date=2016-10-29&rft.issn=0362-4331&rft.aulast=Hakim&rft.aufirst=Danny&rft_id=https%3A%2F%2Fwww.nytimes.com%2F2016%2F10%2F30%2Fbusiness%2Fgmo-promise-falls-short.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-188"><a href="#cite_ref-188">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFArealRiesgoRodríguez-Cerezo2013" class="citation journal cs1">Areal FJ, Riesgo L, Rodríguez-Cerezo E (1 February 2013). "Economic and agronomic impact of commercialized GM crops: a meta-analysis". The Journal of Agricultural Science. 151 (1): 7–33. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1017%2FS0021859612000111">10.1017/S0021859612000111</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:85891950">85891950</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Agricultural+Science&rft.atitle=Economic+and+agronomic+impact+of+commercialized+GM+crops%3A+a+meta-analysis&rft.volume=151&rft.issue=1&rft.pages=7-33&rft.date=2013-02-01&rft_id=info%3Adoi%2F10.1017%2FS0021859612000111&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A85891950%23id-name%3DS2CID&rft.aulast=Areal&rft.aufirst=FJ&rft.au=Riesgo%2C+L&rft.au=Rodr%C3%ADguez-Cerezo%2C+E&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-189"><a href="#cite_ref-189">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFingerEl_BenniKaphengstEvans2011" class="citation journal cs1">Finger R, El Benni N, Kaphengst T, Evans C, Herbert S, Lehmann B, Morse S, Stupak N (10 May 2011). <a rel="nofollow" class="external text" href="https://www.research-collection.ethz.ch/bitstream/20.500.11850/42242/1/sustainability-03-00743.pdf">"A Meta Analysis on Farm-Level Costs and Benefits of GM Crops"</a> (PDF). Sustainability. 3 (5): 743–62. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3390%2Fsu3050743">10.3390/su3050743</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20180719124037/https://www.research-collection.ethz.ch/bitstream/20.500.11850/42242/1/sustainability-03-00743.pdf">Archived</a> (PDF) from the original on 19 July 2018.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Sustainability&rft.atitle=A+Meta+Analysis+on+Farm-Level+Costs+and+Benefits+of+GM+Crops&rft.volume=3&rft.issue=5&rft.pages=743-62&rft.date=2011-05-10&rft_id=info%3Adoi%2F10.3390%2Fsu3050743&rft.aulast=Finger&rft.aufirst=Robert&rft.au=El+Benni%2C+Nadja&rft.au=Kaphengst%2C+Timo&rft.au=Evans%2C+Clive&rft.au=Herbert%2C+Sophie&rft.au=Lehmann%2C+Bernard&rft.au=Morse%2C+Stephen&rft.au=Stupak%2C+Nataliya&rft_id=https%3A%2F%2Fwww.research-collection.ethz.ch%2Fbitstream%2F20.500.11850%2F42242%2F1%2Fsustainability-03-00743.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-190"><a href="#cite_ref-190">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKlümperQaim2014" class="citation journal cs1">Klümper W, Qaim M (3 November 2014). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218791">"A meta-analysis of the impacts of genetically modified crops"</a>. PLOS ONE. 9 (11): e111629. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2014PLoSO...9k1629K">2014PLoSO...9k1629K</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.pone.0111629">10.1371/journal.pone.0111629</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218791">4218791</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25365303">25365303</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLOS+ONE&rft.atitle=A+meta-analysis+of+the+impacts+of+genetically+modified+crops&rft.volume=9&rft.issue=11&rft.pages=e111629&rft.date=2014-11-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4218791%23id-name%3DPMC&rft_id=info%3Apmid%2F25365303&rft_id=info%3Adoi%2F10.1371%2Fjournal.pone.0111629&rft_id=info%3Abibcode%2F2014PLoSO...9k1629K&rft.aulast=Kl%C3%BCmper&rft.aufirst=W&rft.au=Qaim%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4218791&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-191"><a href="#cite_ref-191">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFQiu2013" class="citation journal cs1"><a href="/wiki/Jane_Qiu" title="Jane Qiu">Qiu J</a> (2013). <a rel="nofollow" class="external text" href="http://www.nature.com/news/genetically-modified-crops-pass-benefits-to-weeds-1.13517">"Genetically modified crops pass benefits to weeds"</a>. Nature. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnature.2013.13517">10.1038/nature.2013.13517</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:87415065">87415065</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Genetically+modified+crops+pass+benefits+to+weeds&rft.date=2013&rft_id=info%3Adoi%2F10.1038%2Fnature.2013.13517&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A87415065%23id-name%3DS2CID&rft.aulast=Qiu&rft.aufirst=Jane&rft_id=http%3A%2F%2Fwww.nature.com%2Fnews%2Fgenetically-modified-crops-pass-benefits-to-weeds-1.13517&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-:1-192">^ <a href="#cite_ref-:1_192-0">a</a> <a href="#cite_ref-:1_192-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.fao.org/docrep/003/X9602E/x9602e07.htm">"GMOs and the environment"</a>. www.fao.org. Retrieved 7 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.fao.org&rft.atitle=GMOs+and+the+environment&rft_id=http%3A%2F%2Fwww.fao.org%2Fdocrep%2F003%2FX9602E%2Fx9602e07.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-193"><a href="#cite_ref-193">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDivelyVenugopalFinkenbinder2016" class="citation journal cs1">Dively GP, Venugopal PD, Finkenbinder C (30 December 2016). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201267">"Field-Evolved Resistance in Corn Earworm to Cry Proteins Expressed by Transgenic Sweet Corn"</a>. PLOS ONE. 11 (12): e0169115. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2016PLoSO..1169115D">2016PLoSO..1169115D</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1371%2Fjournal.pone.0169115">10.1371/journal.pone.0169115</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5201267">5201267</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/28036388">28036388</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLOS+ONE&rft.atitle=Field-Evolved+Resistance+in+Corn+Earworm+to+Cry+Proteins+Expressed+by+Transgenic+Sweet+Corn&rft.volume=11&rft.issue=12&rft.pages=e0169115&rft.date=2016-12-30&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5201267%23id-name%3DPMC&rft_id=info%3Apmid%2F28036388&rft_id=info%3Adoi%2F10.1371%2Fjournal.pone.0169115&rft_id=info%3Abibcode%2F2016PLoSO..1169115D&rft.aulast=Dively&rft.aufirst=GP&rft.au=Venugopal%2C+PD&rft.au=Finkenbinder%2C+C&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5201267&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-194"><a href="#cite_ref-194">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFQiu2010" class="citation journal cs1">Qiu, Jane (13 May 2010). "GM crop use makes minor pests major problem". Nature News. <a href="/wiki/CiteSeerX_(identifier)" class="mw-redirect" title="CiteSeerX (identifier)">CiteSeerX</a> <a rel="nofollow" class="external text" href="https://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.464.7885">10.1.1.464.7885</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnews.2010.242">10.1038/news.2010.242</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+News&rft.atitle=GM+crop+use+makes+minor+pests+major+problem&rft.date=2010-05-13&rft_id=https%3A%2F%2Fciteseerx.ist.psu.edu%2Fviewdoc%2Fsummary%3Fdoi%3D10.1.1.464.7885%23id-name%3DCiteSeerX&rft_id=info%3Adoi%2F10.1038%2Fnews.2010.242&rft.aulast=Qiu&rft.aufirst=Jane&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-195"><a href="#cite_ref-195">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGilbert2013" class="citation journal cs1">Gilbert N (May 2013). "Case studies: A hard look at GM crops". Nature. 497 (7447): 24–6. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2013Natur.497...24G">2013Natur.497...24G</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F497024a">10.1038/497024a</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23636378">23636378</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:4417399">4417399</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Case+studies%3A+A+hard+look+at+GM+crops&rft.volume=497&rft.issue=7447&rft.pages=24-6&rft.date=2013-05&rft_id=info%3Adoi%2F10.1038%2F497024a&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A4417399%23id-name%3DS2CID&rft_id=info%3Apmid%2F23636378&rft_id=info%3Abibcode%2F2013Natur.497...24G&rft.aulast=Gilbert&rft.aufirst=N&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-196"><a href="#cite_ref-196">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.nature.com/scitable/blog/accumulating-glitches/are_gmo_fish_safe_for">"Are GMO Fish Safe for the Environment? | Accumulating Glitches | Learn Science at Scitable"</a>. www.nature.com. Retrieved 7 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.nature.com&rft.atitle=Are+GMO+Fish+Safe+for+the+Environment%3F+%7C+Accumulating+Glitches+%7C+Learn+Science+at+Scitable&rft_id=https%3A%2F%2Fwww.nature.com%2Fscitable%2Fblog%2Faccumulating-glitches%2Fare_gmo_fish_safe_for&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-197"><a href="#cite_ref-197">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.who.int/foodsafety/areas_work/food-technology/faq-genetically-modified-food/en/">"Q&A: genetically modified food"</a>. World Health Organization. Retrieved 7 May 2017.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=World+Health+Organization&rft.atitle=Q%26A%3A+genetically+modified+food&rft_id=https%3A%2F%2Fwww.who.int%2Ffoodsafety%2Fareas_work%2Ffood-technology%2Ffaq-genetically-modified-food%2Fen%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-198"><a href="#cite_ref-198">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNicoliaManzoVeronesiRosellini2014" class="citation journal cs1">Nicolia A, Manzo A, Veronesi F, Rosellini D (March 2014). "An overview of the last 10 years of genetically engineered crop safety research". Critical Reviews in Biotechnology. 34 (1): 77–88. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3109%2F07388551.2013.823595">10.3109/07388551.2013.823595</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24041244">24041244</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:9836802">9836802</a>. <q>We have reviewed the scientific literature on GE crop safety for the last 10 years that catches the scientific consensus matured since GE plants became widely cultivated worldwide, and we can conclude that the scientific research conducted so far has not detected any significant hazard directly connected with the use of GM crops. The literature about Biodiversity and the GE food/feed consumption has sometimes resulted in animated debate regarding the suitability of the experimental designs, the choice of the statistical methods or the public accessibility of data. Such debate, even if positive and part of the natural process of review by the scientific community, has frequently been distorted by the media and often used politically and inappropriately in anti-GE crops campaigns.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Critical+Reviews+in+Biotechnology&rft.atitle=An+overview+of+the+last+10+years+of+genetically+engineered+crop+safety+research&rft.volume=34&rft.issue=1&rft.pages=77-88&rft.date=2014-03&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A9836802%23id-name%3DS2CID&rft_id=info%3Apmid%2F24041244&rft_id=info%3Adoi%2F10.3109%2F07388551.2013.823595&rft.aulast=Nicolia&rft.aufirst=A&rft.au=Manzo%2C+A&rft.au=Veronesi%2C+F&rft.au=Rosellini%2C+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-199"><a href="#cite_ref-199">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.fao.org/docrep/006/Y5160E/y5160e10.htm#P3_1651The">"State of Food and Agriculture 2003–2004. Agricultural Biotechnology: Meeting the Needs of the Poor. Health and environmental impacts of transgenic crops"</a>. Food and Agriculture Organization of the United Nations. Retrieved 8 February 2016. <q>Currently available transgenic crops and foods derived from them have been judged safe to eat and the methods used to test their safety have been deemed appropriate. These conclusions represent the consensus of the scientific evidence surveyed by the ICSU (2003) and they are consistent with the views of the World Health Organization (WHO, 2002). These foods have been assessed for increased risks to human health by several national regulatory authorities (inter alia, Argentina, Brazil, Canada, China, the United Kingdom and the United States) using their national food safety procedures (ICSU). To date no verifiable untoward toxic or nutritionally deleterious effects resulting from the consumption of foods derived from genetically modified crops have been discovered anywhere in the world (GM Science Review Panel). Many millions of people have consumed foods derived from GM plants – mainly maize, soybean and oilseed rape – without any observed adverse effects (ICSU).</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=State+of+Food+and+Agriculture+2003%E2%80%932004.+Agricultural+Biotechnology%3A+Meeting+the+Needs+of+the+Poor.+Health+and+environmental+impacts+of+transgenic+crops&rft.pub=Food+and+Agriculture+Organization+of+the+United+Nations&rft_id=http%3A%2F%2Fwww.fao.org%2Fdocrep%2F006%2FY5160E%2Fy5160e10.htm%23P3_1651The&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-200"><a href="#cite_ref-200">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRonald2011" class="citation journal cs1">Ronald P (May 2011). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120150">"Plant genetics, sustainable agriculture and global food security"</a>. Genetics. 188 (1): 11–20. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1534%2Fgenetics.111.128553">10.1534/genetics.111.128553</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120150">3120150</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21546547">21546547</a>. <q>There is broad scientific consensus that genetically engineered crops currently on the market are safe to eat. After 14 years of cultivation and a cumulative total of 2 billion acres planted, no adverse health or environmental effects have resulted from commercialization of genetically engineered crops (Board on Agriculture and Natural Resources, Committee on Environmental Impacts Associated with Commercialization of Transgenic Plants, National Research Council and Division on Earth and Life Studies 2002). Both the U.S. National Research Council and the Joint Research Centre (the European Union's scientific and technical research laboratory and an integral part of the European Commission) have concluded that there is a comprehensive body of knowledge that adequately addresses the food safety issue of genetically engineered crops (Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health and National Research Council 2004; European Commission Joint Research Centre 2008). These and other recent reports conclude that the processes of genetic engineering and conventional breeding are no different in terms of unintended consequences to human health and the environment (European Commission Directorate-General for Research and Innovation 2010).</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genetics&rft.atitle=Plant+genetics%2C+sustainable+agriculture+and+global+food+security&rft.volume=188&rft.issue=1&rft.pages=11-20&rft.date=2011-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3120150%23id-name%3DPMC&rft_id=info%3Apmid%2F21546547&rft_id=info%3Adoi%2F10.1534%2Fgenetics.111.128553&rft.aulast=Ronald&rft.aufirst=P&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3120150&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-201"><a href="#cite_ref-201">^</a> But see also: <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDomingoGiné_Bordonaba2011" class="citation journal cs1">Domingo JL, Giné Bordonaba J (May 2011). "A literature review on the safety assessment of genetically modified plants". Environment International. 37 (4): 734–42. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2011EnInt..37..734D">2011EnInt..37..734D</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.envint.2011.01.003">10.1016/j.envint.2011.01.003</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21296423">21296423</a>. <q>In spite of this, the number of studies specifically focused on safety assessment of GM plants is still limited. However, it is important to remark that for the first time, a certain equilibrium in the number of research groups suggesting, on the basis of their studies, that a number of varieties of GM products (mainly maize and soybeans) are as safe and nutritious as the respective conventional non-GM plant, and those raising still serious concerns, was observed. Moreover, it is worth mentioning that most of the studies demonstrating that GM foods are as nutritional and safe as those obtained by conventional breeding, have been performed by biotechnology companies or associates, which are also responsible of commercializing these GM plants. Anyhow, this represents a notable advance in comparison with the lack of studies published in recent years in scientific journals by those companies.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Environment+International&rft.atitle=A+literature+review+on+the+safety+assessment+of+genetically+modified+plants&rft.volume=37&rft.issue=4&rft.pages=734-42&rft.date=2011-05&rft_id=info%3Apmid%2F21296423&rft_id=info%3Adoi%2F10.1016%2Fj.envint.2011.01.003&rft_id=info%3Abibcode%2F2011EnInt..37..734D&rft.aulast=Domingo&rft.aufirst=JL&rft.au=Gin%C3%A9+Bordonaba%2C+J&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKrimsky2015" class="citation journal cs1">Krimsky S (2015). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20160207171524/http://www.tufts.edu/~skrimsky/PDF/Illusory%20Consensus%20GMOs.PDF">"An Illusory Consensus behind GMO Health Assessment"</a> (PDF). Science, Technology, & Human Values. 40 (6): 883–914. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1177%2F0162243915598381">10.1177/0162243915598381</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:40855100">40855100</a>. Archived from <a rel="nofollow" class="external text" href="http://www.tufts.edu/~skrimsky/PDF/Illusory%20Consensus%20GMOs.PDF">the original</a> (PDF) on 7 February 2016. Retrieved 30 October 2016. <q>I began this article with the testimonials from respected scientists that there is literally no scientific controversy over the health effects of GMOs. My investigation into the scientific literature tells another story.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science%2C+Technology%2C+%26+Human+Values&rft.atitle=An+Illusory+Consensus+behind+GMO+Health+Assessment&rft.volume=40&rft.issue=6&rft.pages=883-914&rft.date=2015&rft_id=info%3Adoi%2F10.1177%2F0162243915598381&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A40855100%23id-name%3DS2CID&rft.aulast=Krimsky&rft.aufirst=Sheldon&rft_id=http%3A%2F%2Fwww.tufts.edu%2F~skrimsky%2FPDF%2FIllusory%2520Consensus%2520GMOs.PDF&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> And contrast: <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPanchinTuzhikov2017" class="citation journal cs1">Panchin AY, Tuzhikov AI (March 2017). "Published GMO studies find no evidence of harm when corrected for multiple comparisons". Critical Reviews in Biotechnology. 37 (2): 213–217. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3109%2F07388551.2015.1130684">10.3109/07388551.2015.1130684</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26767435">26767435</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:11786594">11786594</a>. <q>Here, we show that a number of articles some of which have strongly and negatively influenced the public opinion on GM crops and even provoked political actions, such as GMO embargo, share common flaws in the statistical evaluation of the data. Having accounted for these flaws, we conclude that the data presented in these articles does not provide any substantial evidence of GMO harm. The presented articles suggesting possible harm of GMOs received high public attention. However, despite their claims, they actually weaken the evidence for the harm and lack of substantial equivalency of studied GMOs. We emphasize that with over 1783 published articles on GMOs over the last 10 years it is expected that some of them should have reported undesired differences between GMOs and conventional crops even if no such differences exist in reality.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Critical+Reviews+in+Biotechnology&rft.atitle=Published+GMO+studies+find+no+evidence+of+harm+when+corrected+for+multiple+comparisons&rft.volume=37&rft.issue=2&rft.pages=213-217&rft.date=2017-03&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A11786594%23id-name%3DS2CID&rft_id=info%3Apmid%2F26767435&rft_id=info%3Adoi%2F10.3109%2F07388551.2015.1130684&rft.aulast=Panchin&rft.aufirst=AY&rft.au=Tuzhikov%2C+AI&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> and <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFYangChen2016" class="citation journal cs1">Yang YT, Chen B (April 2016). "Governing GMOs in the USA: science, law and public health". Journal of the Science of Food and Agriculture. 96 (6): 1851–5. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2016JSFA...96.1851Y">2016JSFA...96.1851Y</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fjsfa.7523">10.1002/jsfa.7523</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26536836">26536836</a>. <q>It is therefore not surprising that efforts to require labeling and to ban GMOs have been a growing political issue in the USA (citing Domingo and Bordonaba, 2011). Overall, a broad scientific consensus holds that currently marketed GM food poses no greater risk than conventional food... Major national and international science and medical associations have stated that no adverse human health effects related to GMO food have been reported or substantiated in peer-reviewed literature to date. Despite various concerns, today, the American Association for the Advancement of Science, the World Health Organization, and many independent international science organizations agree that GMOs are just as safe as other foods. Compared with conventional breeding techniques, genetic engineering is far more precise and, in most cases, less likely to create an unexpected outcome.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+the+Science+of+Food+and+Agriculture&rft.atitle=Governing+GMOs+in+the+USA%3A+science%2C+law+and+public+health&rft.volume=96&rft.issue=6&rft.pages=1851-5&rft.date=2016-04&rft_id=info%3Apmid%2F26536836&rft_id=info%3Adoi%2F10.1002%2Fjsfa.7523&rft_id=info%3Abibcode%2F2016JSFA...96.1851Y&rft.aulast=Yang&rft.aufirst=YT&rft.au=Chen%2C+B&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-202"><a href="#cite_ref-202">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.aaas.org/sites/default/files/AAAS_GM_statement.pdf">"Statement by the AAAS Board of Directors on Labeling of Genetically Modified Foods"</a> (PDF). American Association for the Advancement of Science. 20 October 2012. Retrieved 8 February 2016. <q>The EU, for example, has invested more than €300 million in research on the biosafety of GMOs. Its recent report states: "The main conclusion to be drawn from the efforts of more than 130 research projects, covering a period of more than 25 years of research and involving more than 500 independent research groups, is that biotechnology, and in particular GMOs, are not per se more risky than e.g. conventional plant breeding technologies." The World Health Organization, the American Medical Association, the U.S. National Academy of Sciences, the British Royal Society, and every other respected organization that has examined the evidence has come to the same conclusion: consuming foods containing ingredients derived from GM crops is no riskier than consuming the same foods containing ingredients from crop plants modified by conventional plant improvement techniques.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Statement+by+the+AAAS+Board+of+Directors+on+Labeling+of+Genetically+Modified+Foods&rft.pub=American+Association+for+the+Advancement+of+Science&rft.date=2012-10-20&rft_id=http%3A%2F%2Fwww.aaas.org%2Fsites%2Fdefault%2Ffiles%2FAAAS_GM_statement.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPinholster2012" class="citation web cs1">Pinholster G (25 October 2012). <a rel="nofollow" class="external text" href="http://www.aaas.org/news/aaas-board-directors-legally-mandating-gm-food-labels-could-%E2%80%9Cmislead-and-falsely-alarm">"AAAS Board of Directors: Legally Mandating GM Food Labels Could "Mislead and Falsely Alarm Consumers""</a>. American Association for the Advancement of Science. Retrieved 8 February 2016.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=AAAS+Board+of+Directors%3A+Legally+Mandating+GM+Food+Labels+Could+%22Mislead+and+Falsely+Alarm+Consumers%22&rft.pub=American+Association+for+the+Advancement+of+Science&rft.date=2012-10-25&rft.aulast=Pinholster&rft.aufirst=Ginger&rft_id=http%3A%2F%2Fwww.aaas.org%2Fnews%2Faaas-board-directors-legally-mandating-gm-food-labels-could-%25E2%2580%259Cmislead-and-falsely-alarm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-203"><a href="#cite_ref-203">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFEuropean_Commission._Directorate-General_for_Research2010" class="citation book cs1">European Commission. Directorate-General for Research (2010). <a rel="nofollow" class="external text" href="http://ec.europa.eu/research/biosociety/pdf/a_decade_of_eu-funded_gmo_research.pdf">A decade of EU-funded GMO research (2001–2010)</a> (PDF). Directorate-General for Research and Innovation. Biotechnologies, Agriculture, Food. European Commission, European Union. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2777%2F97784">10.2777/97784</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-92-79-16344-9" title="Special:BookSources/978-92-79-16344-9"><bdi>978-92-79-16344-9</bdi></a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20101224152216/http://ec.europa.eu/research/biosociety/pdf/a_decade_of_eu-funded_gmo_research.pdf">Archived</a> (PDF) from the original on 24 December 2010. Retrieved 8 February 2016.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=A+decade+of+EU-funded+GMO+research+%282001%E2%80%932010%29&rft.pub=Directorate-General+for+Research+and+Innovation.+Biotechnologies%2C+Agriculture%2C+Food.+European+Commission%2C+European+Union.&rft.date=2010&rft_id=info%3Adoi%2F10.2777%2F97784&rft.isbn=978-92-79-16344-9&rft.au=European+Commission.+Directorate-General+for+Research&rft_id=http%3A%2F%2Fec.europa.eu%2Fresearch%2Fbiosociety%2Fpdf%2Fa_decade_of_eu-funded_gmo_research.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-204"><a href="#cite_ref-204">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.isaaa.org/kc/Publications/htm/articles/Position/ama.htm">"AMA Report on Genetically Modified Crops and Foods (online summary)"</a>. American Medical Association. January 2001. Retrieved 19 March 2016. <q>A report issued by the scientific council of the American Medical Association (AMA) says that no long-term health effects have been detected from the use of transgenic crops and genetically modified foods, and that these foods are substantially equivalent to their conventional counterparts. (from online summary prepared by <a href="/wiki/International_Service_for_the_Acquisition_of_Agri-biotech_Applications" title="International Service for the Acquisition of Agri-biotech Applications">ISAAA</a>)" "Crops and foods produced using recombinant DNA techniques have been available for fewer than 10 years and no long-term effects have been detected to date. These foods are substantially equivalent to their conventional counterparts.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=AMA+Report+on+Genetically+Modified+Crops+and+Foods+%28online+summary%29&rft.pub=American+Medical+Association&rft.date=2001-01&rft_id=https%3A%2F%2Fwww.isaaa.org%2Fkc%2FPublications%2Fhtm%2Farticles%2FPosition%2Fama.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20120907023039/http://www.ama-assn.org/resources/doc/csaph/a12-csaph2-bioengineeredfoods.pdf">"Report 2 of the Council on Science and Public Health (A-12): Labeling of Bioengineered Foods"</a> (PDF). American Medical Association. 2012. Archived from the original on 7 September 2012. Retrieved 19 March 2016. <q>Bioengineered foods have been consumed for close to 20 years, and during that time, no overt consequences on human health have been reported and/or substantiated in the peer-reviewed literature.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Report+2+of+the+Council+on+Science+and+Public+Health+%28A-12%29%3A+Labeling+of+Bioengineered+Foods&rft.pub=American+Medical+Association&rft.date=2012&rft_id=http%3A%2F%2Fwww.ama-assn.org%2Fresources%2Fdoc%2Fcsaph%2Fa12-csaph2-bioengineeredfoods.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"><code class="cs1-code">{{<a href="/wiki/Template:Cite_web" title="Template:Cite web">cite web</a>}}</code>: CS1 maint: bot: original URL status unknown (<a href="/wiki/Category:CS1_maint:_bot:_original_URL_status_unknown" title="Category:CS1 maint: bot: original URL status unknown">link</a>) </li> <li id="cite_note-205"><a href="#cite_ref-205">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.loc.gov/law/help/restrictions-on-gmos/usa.php#Opinion">"Restrictions on Genetically Modified Organisms: United States. Public and Scholarly Opinion"</a>. Library of Congress. 9 June 2015. Retrieved 8 February 2016. <q>Several scientific organizations in the US have issued studies or statements regarding the safety of GMOs indicating that there is no evidence that GMOs present unique safety risks compared to conventionally bred products. These include the National Research Council, the American Association for the Advancement of Science, and the American Medical Association. Groups in the US opposed to GMOs include some environmental organizations, organic farming organizations, and consumer organizations. A substantial number of legal academics have criticized the US's approach to regulating GMOs.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Restrictions+on+Genetically+Modified+Organisms%3A+United+States.+Public+and+Scholarly+Opinion&rft.pub=Library+of+Congress&rft.date=2015-06-09&rft_id=https%3A%2F%2Fwww.loc.gov%2Flaw%2Fhelp%2Frestrictions-on-gmos%2Fusa.php%23Opinion&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-206"><a href="#cite_ref-206">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFNational_Academies_of_SciencesDivision_on_Earth_Life_StudiesBoard_on_Agriculture_Natural_ResourcesCommittee_on_Genetically_Engineered_Crops:_Past_Experience_Future_Prospects2016" class="citation book cs1">National Academies of Sciences, Engineering; Division on Earth Life Studies; Board on Agriculture Natural Resources; Committee on Genetically Engineered Crops: Past Experience Future Prospects (2016). <a rel="nofollow" class="external text" href="http://www.nap.edu/read/23395/chapter/7#149">Genetically Engineered Crops: Experiences and Prospects</a>. The National Academies of Sciences, Engineering, and Medicine (US). p. 149. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.17226%2F23395">10.17226/23395</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-309-43738-7" title="Special:BookSources/978-0-309-43738-7"><bdi>978-0-309-43738-7</bdi></a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/28230933">28230933</a>. Retrieved 19 May 2016. <q>Overall finding on purported adverse effects on human health of foods derived from GE crops: On the basis of detailed examination of comparisons of currently commercialized GE with non-GE foods in compositional analysis, acute and chronic animal toxicity tests, long-term data on health of livestock fed GE foods, and human epidemiological data, the committee found no differences that implicate a higher risk to human health from GE foods than from their non-GE counterparts.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Genetically+Engineered+Crops%3A+Experiences+and+Prospects&rft.pages=149&rft.pub=The+National+Academies+of+Sciences%2C+Engineering%2C+and+Medicine+%28US%29&rft.date=2016&rft_id=info%3Apmid%2F28230933&rft_id=info%3Adoi%2F10.17226%2F23395&rft.isbn=978-0-309-43738-7&rft.aulast=National+Academies+of+Sciences&rft.aufirst=Engineering&rft.au=Division+on+Earth+Life+Studies&rft.au=Board+on+Agriculture+Natural+Resources&rft.au=Committee+on+Genetically+Engineered+Crops%3A+Past+Experience+Future+Prospects&rft_id=http%3A%2F%2Fwww.nap.edu%2Fread%2F23395%2Fchapter%2F7%23149&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-207"><a href="#cite_ref-207">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.who.int/foodsafety/areas_work/food-technology/faq-genetically-modified-food/en/">"Frequently asked questions on genetically modified foods"</a>. World Health Organization. Retrieved 8 February 2016. <q>Different GM organisms include different genes inserted in different ways. This means that individual GM foods and their safety should be assessed on a case-by-case basis and that it is not possible to make general statements on the safety of all GM foods. GM foods currently available on the international market have passed safety assessments and are not likely to present risks for human health. In addition, no effects on human health have been shown as a result of the consumption of such foods by the general population in the countries where they have been approved. Continuous application of safety assessments based on the Codex Alimentarius principles and, where appropriate, adequate post market monitoring, should form the basis for ensuring the safety of GM foods.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Frequently+asked+questions+on+genetically+modified+foods&rft.pub=World+Health+Organization&rft_id=https%3A%2F%2Fwww.who.int%2Ffoodsafety%2Fareas_work%2Ffood-technology%2Ffaq-genetically-modified-food%2Fen%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-208"><a href="#cite_ref-208">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHaslberger2003" class="citation journal cs1">Haslberger AG (July 2003). "Codex guidelines for GM foods include the analysis of unintended effects". Nature Biotechnology. 21 (7): 739–41. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnbt0703-739">10.1038/nbt0703-739</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12833088">12833088</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:2533628">2533628</a>. <q>These principles dictate a case-by-case premarket assessment that includes an evaluation of both direct and unintended effects.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+Biotechnology&rft.atitle=Codex+guidelines+for+GM+foods+include+the+analysis+of+unintended+effects&rft.volume=21&rft.issue=7&rft.pages=739-41&rft.date=2003-07&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A2533628%23id-name%3DS2CID&rft_id=info%3Apmid%2F12833088&rft_id=info%3Adoi%2F10.1038%2Fnbt0703-739&rft.aulast=Haslberger&rft.aufirst=AG&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-209"><a href="#cite_ref-209">^</a> Some medical organizations, including the <a href="/wiki/British_Medical_Association" title="British Medical Association">British Medical Association</a>, advocate further caution based upon the <a href="/wiki/Precautionary_principle" title="Precautionary principle">precautionary principle</a>:<link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.argenbio.org/adc/uploads/pdf/bma.pdf">"Genetically modified foods and health: a second interim statement"</a> (PDF). British Medical Association. March 2004. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20140322224425/http://www.argenbio.org/adc/uploads/pdf/bma.pdf">Archived</a> (PDF) from the original on 22 March 2014. Retrieved 21 March 2016. <q>In our view, the potential for GM foods to cause harmful health effects is very small and many of the concerns expressed apply with equal vigour to conventionally derived foods. However, safety concerns cannot, as yet, be dismissed completely on the basis of information currently available. When seeking to optimise the balance between benefits and risks, it is prudent to err on the side of caution and, above all, learn from accumulating knowledge and experience. Any new technology such as genetic modification must be examined for possible benefits and risks to human health and the environment. As with all novel foods, safety assessments in relation to GM foods must be made on a case-by-case basis. Members of the GM jury project were briefed on various aspects of genetic modification by a diverse group of acknowledged experts in the relevant subjects. The GM jury reached the conclusion that the sale of GM foods currently available should be halted and the moratorium on commercial growth of GM crops should be continued. These conclusions were based on the precautionary principle and lack of evidence of any benefit. The Jury expressed concern over the impact of GM crops on farming, the environment, food safety and other potential health effects. The Royal Society review (2002) concluded that the risks to human health associated with the use of specific viral DNA sequences in GM plants are negligible, and while calling for caution in the introduction of potential allergens into food crops, stressed the absence of evidence that commercially available GM foods cause clinical allergic manifestations. The BMA shares the view that there is no robust evidence to prove that GM foods are unsafe but we endorse the call for further research and surveillance to provide convincing evidence of safety and benefit.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Genetically+modified+foods+and+health%3A+a+second+interim+statement&rft.pub=British+Medical+Association&rft.date=2004-03&rft_id=http%3A%2F%2Fwww.argenbio.org%2Fadc%2Fuploads%2Fpdf%2Fbma.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-210"><a href="#cite_ref-210">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFunkRainie2015" class="citation web cs1">Funk C, Rainie L (29 January 2015). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20190109232405/http://www.pewinternet.org/2015/01/29/public-and-scientists-views-on-science-and-society/">"Public and Scientists' Views on Science and Society"</a>. Pew Research Center. Archived from <a rel="nofollow" class="external text" href="http://www.pewinternet.org/2015/01/29/public-and-scientists-views-on-science-and-society/">the original</a> on 9 January 2019. Retrieved 24 February 2016. <q>The largest differences between the public and the AAAS scientists are found in beliefs about the safety of eating genetically modified (GM) foods. Nearly nine-in-ten (88%) scientists say it is generally safe to eat GM foods compared with 37% of the general public, a difference of 51 percentage points.</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Public+and+Scientists%27+Views+on+Science+and+Society&rft.pub=Pew+Research+Center&rft.date=2015-01-29&rft.aulast=Funk&rft.aufirst=Cary&rft.au=Rainie%2C+Lee&rft_id=http%3A%2F%2Fwww.pewinternet.org%2F2015%2F01%2F29%2Fpublic-and-scientists-views-on-science-and-society%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-211"><a href="#cite_ref-211">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMarris2001" class="citation journal cs1">Marris C (July 2001). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1083956">"Public views on GMOs: deconstructing the myths. Stakeholders in the GMO debate often describe public opinion as irrational. But do they really understand the public?"</a>. EMBO Reports. 2 (7): 545–8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fembo-reports%2Fkve142">10.1093/embo-reports/kve142</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1083956">1083956</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11463731">11463731</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=EMBO+Reports&rft.atitle=Public+views+on+GMOs%3A+deconstructing+the+myths.+Stakeholders+in+the+GMO+debate+often+describe+public+opinion+as+irrational.+But+do+they+really+understand+the+public%3F&rft.volume=2&rft.issue=7&rft.pages=545-8&rft.date=2001-07&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1083956%23id-name%3DPMC&rft_id=info%3Apmid%2F11463731&rft_id=info%3Adoi%2F10.1093%2Fembo-reports%2Fkve142&rft.aulast=Marris&rft.aufirst=C&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1083956&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-212"><a href="#cite_ref-212">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFinal_Report_of_the_PABE_research_project2001" class="citation web cs1">Final Report of the PABE research project (December 2001). <a rel="nofollow" class="external text" href="http://csec.lancs.ac.uk/archive/pabe/docs/pabe_finalreport.doc">"Public Perceptions of Agricultural Biotechnologies in Europe"</a>. Commission of European Communities. Retrieved 24 February 2016.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Public+Perceptions+of+Agricultural+Biotechnologies+in+Europe&rft.pub=Commission+of+European+Communities&rft.date=2001-12&rft.au=Final+Report+of+the+PABE+research+project&rft_id=http%3A%2F%2Fcsec.lancs.ac.uk%2Farchive%2Fpabe%2Fdocs%2Fpabe_finalreport.doc&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-213"><a href="#cite_ref-213">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFScottInbarRozin2016" class="citation journal cs1">Scott SE, Inbar Y, Rozin P (May 2016). "Evidence for Absolute Moral Opposition to Genetically Modified Food in the United States". Perspectives on Psychological Science. 11 (3): 315–324. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1177%2F1745691615621275">10.1177/1745691615621275</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/27217243">27217243</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:261060">261060</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Perspectives+on+Psychological+Science&rft.atitle=Evidence+for+Absolute+Moral+Opposition+to+Genetically+Modified+Food+in+the+United+States&rft.volume=11&rft.issue=3&rft.pages=315-324&rft.date=2016-05&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A261060%23id-name%3DS2CID&rft_id=info%3Apmid%2F27217243&rft_id=info%3Adoi%2F10.1177%2F1745691615621275&rft.aulast=Scott&rft.aufirst=SE&rft.au=Inbar%2C+Y&rft.au=Rozin%2C+P&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-SFE-214">^ <a href="#cite_ref-SFE_214-0">a</a> <a href="#cite_ref-SFE_214-1">b</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.sf-encyclopedia.com/entry/genetic_engineering">"Genetic Engineering"</a>. The Encyclopedia of Science Fiction. 15 May 2017. Retrieved 19 July 2018.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=The+Encyclopedia+of+Science+Fiction&rft.atitle=Genetic+Engineering&rft.date=2017-05-15&rft_id=http%3A%2F%2Fwww.sf-encyclopedia.com%2Fentry%2Fgenetic_engineering&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-215"><a href="#cite_ref-215">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKoboldt2017" class="citation web cs1">Koboldt D (29 August 2017). <a rel="nofollow" class="external text" href="https://www.outerplaces.com/science/item/16677-genetics-science-fiction-future">"The Science of Sci-Fi: How Science Fiction Predicted the Future of Genetics"</a>. Outer Places. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20180719233445/https://www.outerplaces.com/science/item/16677-genetics-science-fiction-future">Archived</a> from the original on 19 July 2018. Retrieved 19 July 2018.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Outer+Places&rft.atitle=The+Science+of+Sci-Fi%3A+How+Science+Fiction+Predicted+the+Future+of+Genetics&rft.date=2017-08-29&rft.aulast=Koboldt&rft.aufirst=Daniel&rft_id=https%3A%2F%2Fwww.outerplaces.com%2Fscience%2Fitem%2F16677-genetics-science-fiction-future&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Moraga2-216"><a href="#cite_ref-Moraga2_216-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMoraga2009" class="citation journal cs1">Moraga R (November 2009). <a rel="nofollow" class="external text" href="http://clarkesworldmagazine.com/moraga_11_09/">"Modern Genetics in the World of Fiction"</a>. <a href="/wiki/Clarkesworld_Magazine" title="Clarkesworld Magazine">Clarkesworld Magazine</a> (38). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20180719114128/http://clarkesworldmagazine.com/moraga_11_09/">Archived</a> from the original on 19 July 2018.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clarkesworld+Magazine&rft.atitle=Modern+Genetics+in+the+World+of+Fiction&rft.issue=38&rft.date=2009-11&rft.aulast=Moraga&rft.aufirst=Roger&rft_id=http%3A%2F%2Fclarkesworldmagazine.com%2Fmoraga_11_09%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> <li id="cite_note-Wellcome-217">^ <a href="#cite_ref-Wellcome_217-0">a</a> <a href="#cite_ref-Wellcome_217-1">b</a> <a href="#cite_ref-Wellcome_217-2">c</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFClark" class="citation web cs1">Clark M. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20120518055848/http://genome.wellcome.ac.uk/doc_WTD023539.html">"Genetic themes in fiction films: Genetics meets Hollywood"</a>. <a href="/wiki/The_Wellcome_Trust" class="mw-redirect" title="The Wellcome Trust">The Wellcome Trust</a>. Archived from <a rel="nofollow" class="external text" href="http://genome.wellcome.ac.uk/doc_WTD023539.html">the original</a> on 18 May 2012. Retrieved 19 July 2018.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Genetic+themes+in+fiction+films%3A+Genetics+meets+Hollywood&rft.pub=The+Wellcome+Trust&rft.aulast=Clark&rft.aufirst=Michael&rft_id=http%3A%2F%2Fgenome.wellcome.ac.uk%2Fdoc_WTD023539.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=17" title="Edit section: Further reading">edit</a>]</div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin" style=""> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBritish_Medical_Association1999" class="citation book cs1"><a href="/wiki/British_Medical_Association" title="British Medical Association">British Medical Association</a> (1999). The Impact of Genetic Modification on Agriculture, Food and Health. BMJ Books. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/0-7279-1431-6" title="Special:BookSources/0-7279-1431-6"><bdi>0-7279-1431-6</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Impact+of+Genetic+Modification+on+Agriculture%2C+Food+and+Health&rft.pub=BMJ+Books&rft.date=1999&rft.isbn=0-7279-1431-6&rft.au=British+Medical+Association&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDonnellan,_Craig2004" class="citation book cs1">Donnellan, Craig (2004). Genetic Modification (Issues). Independence Educational Publishers. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/1-86168-288-3" title="Special:BookSources/1-86168-288-3"><bdi>1-86168-288-3</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Genetic+Modification+%28Issues%29&rft.pub=Independence+Educational+Publishers&rft.date=2004&rft.isbn=1-86168-288-3&rft.au=Donnellan%2C+Craig&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMorgan2009" class="citation book cs1">Morgan S (1 January 2009). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=48QpTA2P6O0C">Superfoods: Genetic Modification of Foods</a>. Heinemann Library. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-1-4329-2455-3" title="Special:BookSources/978-1-4329-2455-3"><bdi>978-1-4329-2455-3</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Superfoods%3A+Genetic+Modification+of+Foods&rft.pub=Heinemann+Library&rft.date=2009-01-01&rft.isbn=978-1-4329-2455-3&rft.aulast=Morgan&rft.aufirst=Sally&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D48QpTA2P6O0C&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFSmiley,_Sophie2005" class="citation book cs1">Smiley, Sophie (2005). Genetic Modification: Study Guide (Exploring the Issues). Independence Educational Publishers. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/1-86168-307-3" title="Special:BookSources/1-86168-307-3"><bdi>1-86168-307-3</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Genetic+Modification%3A+Study+Guide+%28Exploring+the+Issues%29&rft.pub=Independence+Educational+Publishers&rft.date=2005&rft.isbn=1-86168-307-3&rft.au=Smiley%2C+Sophie&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWatson2007" class="citation book cs1"><a href="/wiki/James_D._Watson" class="mw-redirect" title="James D. Watson">Watson JD</a> (2007). Recombinant DNA: Genes and Genomes: A Short Course. San Francisco: W.H. Freeman. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-7167-2866-5" title="Special:BookSources/978-0-7167-2866-5"><bdi>978-0-7167-2866-5</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Recombinant+DNA%3A+Genes+and+Genomes%3A+A+Short+Course&rft.place=San+Francisco&rft.pub=W.H.+Freeman&rft.date=2007&rft.isbn=978-0-7167-2866-5&rft.aulast=Watson&rft.aufirst=James+D.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWeaverMichael2003" class="citation report cs1">Weaver S, Michael M (2003). <a rel="nofollow" class="external text" href="http://researcharchive.vuw.ac.nz/handle/10063/3">An Annotated Bibliography of Scientific Publications on the Risks Associated with Genetic Modification</a> (Report). Wellington, NZ: Victoria University.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=report&rft.btitle=An+Annotated+Bibliography+of+Scientific+Publications+on+the+Risks+Associated+with+Genetic+Modification&rft.place=Wellington%2C+NZ&rft.pub=Victoria+University&rft.date=2003&rft.aulast=Weaver&rft.aufirst=Sean&rft.au=Michael%2C+Morris&rft_id=http%3A%2F%2Fresearcharchive.vuw.ac.nz%2Fhandle%2F10063%2F3&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFZaidHughesPorcedduNicholas2001" class="citation book cs1">Zaid A, Hughes HG, Porceddu E, Nicholas F (2001). <a rel="nofollow" class="external text" href="http://www.fao.org/docrep/004/y2775e/y2775e00.htm">Glossary of Biotechnology for Food and Agriculture – A Revised and Augmented Edition of the Glossary of Biotechnology and Genetic Engineering</a>. Rome, Italy: <a href="/wiki/FAO" class="mw-redirect" title="FAO">FAO</a>. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/92-5-104683-2" title="Special:BookSources/92-5-104683-2"><bdi>92-5-104683-2</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Glossary+of+Biotechnology+for+Food+and+Agriculture+%E2%80%93+A+Revised+and+Augmented+Edition+of+the+Glossary+of+Biotechnology+and+Genetic+Engineering&rft.place=Rome%2C+Italy&rft.pub=FAO&rft.date=2001&rft.isbn=92-5-104683-2&rft.aulast=Zaid&rft.aufirst=A&rft.au=Hughes%2C+HG&rft.au=Porceddu%2C+E&rft.au=Nicholas%2C+F&rft_id=http%3A%2F%2Fwww.fao.org%2Fdocrep%2F004%2Fy2775e%2Fy2775e00.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AGenetic+engineering" class="Z3988"></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2>[<a href="/w/index.php?title=Genetic_engineering&action=edit&section=18" title="Edit section: External links">edit</a>]</div> <style data-mw-deduplicate="TemplateStyles:r1235681985">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:var(--background-color-interactive-subtle,#f8f9fa);display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output .side-box-text{flex:1;min-width:0}}@media(min-width:720px){.mw-parser-output .side-box{width:238px}.mw-parser-output .side-box-right{clear:right;float:right;margin-left:1em}.mw-parser-output .side-box-left{margin-right:1em}}</style><div class="side-box metadata side-box-right"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style> <div class="side-box-abovebelow"> <a href="/wiki/Wikipedia:The_Wikipedia_Library" title="Wikipedia:The Wikipedia Library">Library resources</a> about Genetic engineering <hr /></div> <div class="side-box-flex"> <div class="side-box-text plainlist"><ul><li><a class="external text" href="https://ftl.toolforge.org/cgi-bin/ftl?st=&su=Genetic+engineering">Resources in your library</a></li> <li><a class="external text" href="https://ftl.toolforge.org/cgi-bin/ftl?st=&su=Genetic+engineering&library=0CHOOSE0">Resources in other libraries</a></li> </ul></div></div> </div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1235681985"><style data-mw-deduplicate="TemplateStyles:r1237033735">@media 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href="/wiki/Special:EditPage/Template:Engineering_fields" title="Special:EditPage/Template:Engineering fields"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Engineering" style="font-size:114%;margin:0 4em"><a href="/wiki/Engineering" title="Engineering">Engineering</a></div></th></tr><tr><td class="navbox-abovebelow" colspan="3"><div> <ul><li><a href="/wiki/History_of_engineering" title="History of engineering">History</a></li> <li><a href="/wiki/Outline_of_engineering" title="Outline of engineering">Outline</a></li> <li><a href="/wiki/List_of_engineering_branches" title="List of engineering branches">List of engineering branches</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Specialties and <a href="/wiki/Interdisciplinarity" title="Interdisciplinarity">Interdisciplinarity</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Civil_engineering" title="Civil engineering">Civil</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Architectural_engineering" title="Architectural engineering">Architectural</a></li> <li><a href="/wiki/Coastal_engineering" title="Coastal engineering">Coastal</a></li> <li><a href="/wiki/Construction_engineering" title="Construction engineering">Construction</a></li> <li><a href="/wiki/Earthquake_engineering" title="Earthquake engineering">Earthquake</a></li> <li><a href="/wiki/Ecological_engineering" title="Ecological engineering">Ecological</a></li> <li><a href="/wiki/Environmental_engineering" title="Environmental engineering">Environmental</a> <ul><li><a href="/wiki/Sanitary_engineering" title="Sanitary engineering">Sanitary</a></li></ul></li> <li><a href="/wiki/Geological_engineering" title="Geological engineering">Geological</a></li> <li><a href="/wiki/Geotechnical_engineering" title="Geotechnical engineering">Geotechnical</a></li> <li><a href="/wiki/Hydraulic_engineering" title="Hydraulic engineering">Hydraulic</a></li> <li><a href="/wiki/Mining_engineering" title="Mining engineering">Mining</a></li> <li><a href="/wiki/Municipal_or_urban_engineering" title="Municipal or urban engineering">Municipal/Urban</a></li> <li><a href="/wiki/Offshore_engineering" class="mw-redirect" title="Offshore engineering">Offshore</a></li> <li><a href="/wiki/River_engineering" title="River engineering">River</a></li> <li><a href="/wiki/Structural_engineering" title="Structural engineering">Structural</a></li> <li><a href="/wiki/Transportation_engineering" title="Transportation engineering">Transportation</a> <ul><li><a href="/wiki/Traffic_engineering_(transportation)" title="Traffic engineering (transportation)">Traffic</a></li> <li><a href="/wiki/Railway_engineering" title="Railway engineering">Railway</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Mechanical_engineering" title="Mechanical engineering">Mechanical</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Acoustical_engineering" title="Acoustical engineering">Acoustic</a></li> <li><a href="/wiki/Aerospace_engineering" title="Aerospace engineering">Aerospace</a></li> <li><a href="/wiki/Automotive_engineering" title="Automotive engineering">Automotive</a></li> <li><a href="/wiki/Biomechanical_engineering" title="Biomechanical engineering">Biomechanical</a></li> <li><a href="/wiki/Energy_engineering" title="Energy engineering">Energy</a></li> <li><a href="/wiki/Manufacturing_engineering" title="Manufacturing engineering">Manufacturing</a></li> <li><a href="/wiki/Marine_engineering" title="Marine engineering">Marine</a></li> <li><a href="/wiki/Naval_architecture" title="Naval architecture">Naval architecture</a></li> <li><a href="/wiki/Railway_engineering" title="Railway engineering">Railway</a></li> <li><a href="/wiki/Sports_engineering" title="Sports engineering">Sports</a></li> <li><a href="/wiki/Thermal_engineering" title="Thermal engineering">Thermal</a></li> <li><a href="/wiki/Tribology" title="Tribology">Tribology</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Electrical_engineering" title="Electrical engineering">Electrical</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Broadcast_engineering" title="Broadcast engineering">Broadcast</a> <ul><li><a href="/wiki/Outline_of_computer_engineering" title="Outline of computer engineering">outline</a></li></ul></li> <li><a href="/wiki/Control_engineering" title="Control engineering">Control</a></li> <li><a href="/wiki/Electromechanics" title="Electromechanics">Electromechanics</a></li> <li><a href="/wiki/Electronic_engineering" title="Electronic engineering">Electronics</a></li> <li><a href="/wiki/Microwave_engineering" title="Microwave engineering">Microwaves</a></li> <li><a href="/wiki/Optical_engineering" title="Optical engineering">Optical</a></li> <li><a href="/wiki/Power_engineering" title="Power engineering">Power</a></li> <li><a href="/wiki/Radio-frequency_engineering" title="Radio-frequency engineering">Radio frequency</a></li> <li><a href="/wiki/Signal_processing" title="Signal processing">Signal processing</a></li> <li><a href="/wiki/Telecommunications_engineering" title="Telecommunications engineering">Telecommunications</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Chemical_engineering" title="Chemical engineering">Chemical</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Biochemical_engineering" title="Biochemical engineering">Biochemical/Bioprocess</a></li> <li><a href="/wiki/Biological_engineering" title="Biological engineering">Biological</a> <ul><li><a href="/wiki/Bioresource_engineering" title="Bioresource engineering">Bioresource</a></li> <li><a class="mw-selflink selflink">Genetic</a></li> <li><a href="/wiki/Tissue_engineering" title="Tissue engineering">Tissue</a></li></ul></li> <li><a href="/wiki/Chemical_reaction_engineering" title="Chemical reaction engineering">Chemical reaction</a></li> <li><a href="/wiki/Electrochemical_engineering" title="Electrochemical engineering">Electrochemical</a></li> <li><a href="/wiki/Food_engineering" title="Food engineering">Food</a></li> <li><a href="/wiki/Molecular_engineering" title="Molecular engineering">Molecular</a></li> <li><a href="/wiki/Paper_engineering" title="Paper engineering">Paper</a></li> <li><a href="/wiki/Petroleum_engineering" title="Petroleum engineering">Petroleum</a></li> <li><a href="/wiki/Process_engineering" title="Process engineering">Process</a></li> <li><a href="/wiki/Chemical_reaction_engineering" title="Chemical reaction engineering">Reaction</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Materials_science" title="Materials science">Materials</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Biomaterial" title="Biomaterial">Biomaterial</a></li> <li><a href="/wiki/Ceramic_engineering" title="Ceramic engineering">Ceramics</a></li> <li><a href="/wiki/Corrosion_engineering" title="Corrosion engineering">Corrosion</a></li> <li><a href="/wiki/Metallurgy" title="Metallurgy">Metallurgy</a></li> <li><a href="/wiki/Molecular_engineering" title="Molecular engineering">Molecular</a></li> <li><a href="/wiki/Nanotechnology" title="Nanotechnology">Nanotechnology</a></li> <li><a href="/wiki/Polymer_engineering" title="Polymer engineering">Polymers</a></li> <li><a href="/wiki/Semiconductor_device" title="Semiconductor device">Semiconductors</a></li> <li><a href="/wiki/Surface_engineering" title="Surface engineering">Surfaces</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Computer_engineering" title="Computer engineering">Computer</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Artificial_intelligence_engineering" title="Artificial intelligence engineering">AI</a></li> <li><a href="/wiki/Computer_engineering" title="Computer engineering">Computer</a></li> <li><a href="/wiki/Cybersecurity_engineering" title="Cybersecurity engineering">Cybersecurity</a></li> <li><a href="/wiki/Data_engineering" title="Data engineering">Data</a></li> <li><a href="/wiki/Computer_network_engineering" title="Computer network engineering">Networks</a></li> <li><a href="/wiki/Robotics_engineering" title="Robotics engineering">Robotics</a></li> <li><a href="/wiki/Software_engineering" title="Software engineering">Software</a></li></ul> </div></td></tr></tbody></table><div></div></td><td class="noviewer navbox-image" rowspan="5" style="width:1px;padding:0 0 0 2px"><div><a href="/wiki/File:Nuvola_apps_kcmsystem.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/3/35/Nuvola_apps_kcmsystem.png/50px-Nuvola_apps_kcmsystem.png" decoding="async" width="50" height="50" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/35/Nuvola_apps_kcmsystem.png/75px-Nuvola_apps_kcmsystem.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/35/Nuvola_apps_kcmsystem.png/100px-Nuvola_apps_kcmsystem.png 2x" data-file-width="128" data-file-height="128" /></a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Engineering_education" title="Engineering education">Engineering education</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bachelor_of_Engineering" title="Bachelor of Engineering">Bachelor of Engineering</a></li> <li><a href="/wiki/Bachelor_of_Science" title="Bachelor of Science">Bachelor of Science</a></li> <li><a href="/wiki/Master%27s_degree" title="Master's degree">Master's degree</a></li> <li><a href="/wiki/Doctorate" title="Doctorate">Doctorate</a></li> <li><a href="/wiki/Graduate_certificate" title="Graduate certificate">Graduate certificate</a></li> <li><a href="/wiki/Engineer%27s_degree" title="Engineer's degree">Engineer's degree</a></li> <li><a href="/wiki/Regulation_and_licensure_in_engineering" title="Regulation and licensure in engineering">Licensed engineer</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Related topics</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Engineer" title="Engineer">Engineer</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Glossary" title="Glossary">Glossaries</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li>Engineering <ul><li><a href="/wiki/Glossary_of_engineering:_A%E2%80%93L" title="Glossary of engineering: A–L">A–L</a></li> <li><a href="/wiki/Glossary_of_engineering:_M%E2%80%93Z" title="Glossary of engineering: M–Z">M–Z</a></li></ul></li> <li><a href="/wiki/Glossary_of_aerospace_engineering" title="Glossary of aerospace engineering">Aerospace engineering</a></li> <li><a href="/wiki/Glossary_of_civil_engineering" title="Glossary of civil engineering">Civil engineering</a></li> <li><a href="/wiki/Glossary_of_electrical_and_electronics_engineering" title="Glossary of electrical and electronics engineering">Electrical and electronics engineering</a></li> <li><a href="/wiki/Glossary_of_mechanical_engineering" title="Glossary of mechanical engineering">Mechanical engineering</a></li> <li><a href="/wiki/Glossary_of_structural_engineering" title="Glossary of structural engineering">Structural engineering</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Agricultural_engineering" title="Agricultural engineering">Agricultural</a></li> <li><a href="/wiki/Audio_engineer" title="Audio engineer">Audio</a></li> <li><a href="/wiki/Automation_engineering" title="Automation engineering">Automation</a></li> <li><a href="/wiki/Biomedical_engineering" title="Biomedical engineering">Biomedical</a> <ul><li><a href="/wiki/Bioinformatics" title="Bioinformatics">Bioinformatics</a></li> <li><a href="/wiki/Clinical_engineering" title="Clinical engineering">Clinical</a></li> <li><a href="/wiki/Health_technology" title="Health technology">Health technology</a></li> <li><a href="/wiki/Pharmaceutical_engineering" title="Pharmaceutical engineering">Pharmaceutical</a></li> <li><a href="/wiki/Rehabilitation_engineering" title="Rehabilitation engineering">Rehabilitation</a></li></ul></li> <li><a href="/wiki/Building_services_engineering" title="Building services engineering">Building services</a> <ul><li><a href="/wiki/Mechanical,_electrical,_and_plumbing" title="Mechanical, electrical, and plumbing">MEP</a></li></ul></li> <li><a href="/wiki/Design_engineer" title="Design engineer">Design</a></li> <li><a href="/wiki/Explosives_engineering" title="Explosives engineering">Explosives</a></li> <li><a href="/wiki/Facilities_engineering" title="Facilities engineering">Facilities</a></li> <li><a href="/wiki/Fire_protection_engineering" title="Fire protection engineering">Fire</a></li> <li><a href="/wiki/Forensic_engineering" title="Forensic engineering">Forensic</a></li> <li><a href="/wiki/Climate_engineering" title="Climate engineering">Climate</a></li> <li><a href="/wiki/Geomatics_engineering" class="mw-redirect" title="Geomatics engineering">Geomatics</a></li> <li><a href="/wiki/Engineering_drawing" title="Engineering drawing">Graphics</a></li> <li><a href="/wiki/Industrial_engineering" title="Industrial engineering">Industrial</a></li> <li><a href="/wiki/Information_engineering" title="Information engineering">Information</a></li> <li><a href="/wiki/Instrumentation_engineering" class="mw-redirect" title="Instrumentation engineering">Instrumentation</a> <ul><li><a href="/wiki/Instrumentation_and_control_engineering" title="Instrumentation and control engineering">and Control</a></li></ul></li> <li><a href="/wiki/Logistics_engineering" title="Logistics engineering">Logistics</a></li> <li><a href="/wiki/Engineering_management" title="Engineering management">Management</a></li> <li><a href="/wiki/Engineering_mathematics" title="Engineering mathematics">Mathematics</a></li> <li><a href="/wiki/Mechatronics" title="Mechatronics">Mechatronics</a></li> <li><a href="/wiki/Military_engineering" title="Military engineering">Military</a></li> <li><a href="/wiki/Nuclear_engineering" title="Nuclear engineering">Nuclear</a></li> <li><a href="/wiki/Ontology_engineering" title="Ontology engineering">Ontology</a></li> <li><a href="/wiki/Packaging_engineering" title="Packaging engineering">Packaging</a></li> <li><a href="/wiki/Engineering_physics" title="Engineering physics">Physics</a></li> <li><a href="/wiki/Privacy_engineering" title="Privacy engineering">Privacy</a></li> <li><a href="/wiki/Safety_engineering" title="Safety engineering">Safety</a></li> <li><a href="/wiki/Security_engineering" title="Security engineering">Security</a></li> <li><a href="/wiki/Survey_engineering" class="mw-redirect" title="Survey engineering">Survey</a></li> <li><a href="/wiki/Sustainable_engineering" title="Sustainable engineering">Sustainability</a></li> <li><a href="/wiki/Systems_engineering" title="Systems engineering">Systems</a></li> <li><a href="/wiki/Textile_engineering" class="mw-redirect" title="Textile engineering">Textile</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="3" style="font-weight:bold;"><div> <ul><li><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /> <a href="/wiki/Category:Engineering" title="Category:Engineering">Category</a></li> <li><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/12px-Commons-logo.svg.png" decoding="async" width="12" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/18px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/24px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /> <a href="https://commons.wikimedia.org/wiki/Engineering" class="extiw" title="commons:Engineering">Commons</a></li> <li><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/16px-People_icon.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/24px-People_icon.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/37/People_icon.svg/32px-People_icon.svg.png 2x" data-file-width="100" data-file-height="100" /> <a href="/wiki/Wikipedia:WikiProject_Engineering" title="Wikipedia:WikiProject Engineering">Wikiproject</a></li> <li><a href="/wiki/File:Symbol_portal_class.svg" class="mw-file-description" title="Portal"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/e/e2/Symbol_portal_class.svg/16px-Symbol_portal_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/e/e2/Symbol_portal_class.svg/23px-Symbol_portal_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/e/e2/Symbol_portal_class.svg/31px-Symbol_portal_class.svg.png 2x" data-file-width="180" data-file-height="185" /></a> <a href="/wiki/Portal:Engineering" title="Portal:Engineering">Portal</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Genetics" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Genetics" title="Template:Genetics"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Genetics" title="Template talk:Genetics"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Genetics" title="Special:EditPage/Template:Genetics"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Genetics" style="font-size:114%;margin:0 4em"><a href="/wiki/Genetics" title="Genetics">Genetics</a></div></th></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><a href="/wiki/Introduction_to_genetics" title="Introduction to genetics">Introduction</a></li> <li><a href="/wiki/Outline_of_genetics" title="Outline of genetics">Outline</a></li> <li><a href="/wiki/History_of_genetics" title="History of genetics">History</a></li> <li><a href="/wiki/Timeline_of_the_history_of_genetics" title="Timeline of the history of genetics">Timeline</a></li> <li><a href="/wiki/Index_of_genetics_articles" title="Index of genetics articles">Index</a></li> <li><a href="/wiki/Glossary_of_genetics" class="mw-redirect" title="Glossary of genetics">Glossary</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Key components</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Chromosome" title="Chromosome">Chromosome</a></li> <li><a href="/wiki/DNA" title="DNA">DNA</a></li> <li><a href="/wiki/RNA" title="RNA">RNA</a></li> <li><a href="/wiki/Genome" title="Genome">Genome</a></li> <li><a href="/wiki/Heredity" title="Heredity">Heredity</a></li> <li><a href="/wiki/Nucleotide" title="Nucleotide">Nucleotide</a></li> <li><a href="/wiki/Mutation" title="Mutation">Mutation</a></li> <li><a href="/wiki/Genetic_variation" title="Genetic variation">Genetic variation</a></li> <li><a href="/wiki/Allele" title="Allele">Allele</a></li> <li><a href="/wiki/Amino_acid" title="Amino acid">Amino acid</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Fields</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Classical_genetics" title="Classical genetics">Classical</a></li> <li><a href="/wiki/Conservation_genetics" title="Conservation genetics">Conservation</a></li> <li><a href="/wiki/Cytogenetics" title="Cytogenetics">Cytogenetics</a></li> <li><a href="/wiki/Ecological_genetics" title="Ecological genetics">Ecological</a></li> <li><a href="/wiki/Immunogenetics" title="Immunogenetics">Immunogenetics</a></li> <li><a href="/wiki/Microbial_genetics" title="Microbial genetics">Microbial</a></li> <li><a href="/wiki/Molecular_genetics" title="Molecular genetics">Molecular</a></li> <li><a href="/wiki/Population_genetics" title="Population genetics">Population</a></li> <li><a href="/wiki/Quantitative_genetics" title="Quantitative genetics">Quantitative</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Archaeogenetics" title="Archaeogenetics">Archaeogenetics</a> of</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Genetic_history_of_Africa" title="Genetic history of Africa">Africa</a></li> <li><a href="/wiki/Genetic_history_of_indigenous_peoples_of_the_Americas" class="mw-redirect" title="Genetic history of indigenous peoples of the Americas">the Americas</a></li> <li><a href="/wiki/Genetic_history_of_the_British_Isles" title="Genetic history of the British Isles">the British Isles</a></li> <li><a href="/wiki/Genetic_history_of_Europe" title="Genetic history of Europe">Europe</a></li> <li><a href="/wiki/Genetic_history_of_Italy" title="Genetic history of Italy">Italy</a></li> <li><a href="/wiki/Genetic_history_of_the_Middle_East" title="Genetic history of the Middle East">the Middle East</a></li> <li><a href="/wiki/Genetics_and_archaeogenetics_of_South_Asia" title="Genetics and archaeogenetics of South Asia">South Asia</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Related topics</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Behavioural_genetics" title="Behavioural genetics">Behavioural genetics</a></li> <li><a href="/wiki/Epigenetics" title="Epigenetics">Epigenetics</a></li> <li><a href="/wiki/Geneticist" title="Geneticist">Geneticist</a></li> <li><a href="/wiki/Genome_editing" title="Genome editing">Genome editing</a></li> <li><a href="/wiki/Genomics" title="Genomics">Genomics</a></li> <li><a href="/wiki/Genetic_code" title="Genetic code">Genetic code</a></li> <li><a class="mw-selflink selflink">Genetic engineering</a></li> <li><a href="/wiki/Genetic_diversity" title="Genetic diversity">Genetic diversity</a></li> <li><a href="/wiki/Genetic_monitoring" title="Genetic monitoring">Genetic monitoring</a></li> <li><a href="/wiki/Genetic_genealogy" title="Genetic genealogy">Genetic genealogy</a></li> <li><a href="/wiki/Heredity" title="Heredity">Heredity</a></li> <li><a href="/wiki/He_Jiankui_affair" title="He Jiankui affair">He Jiankui affair</a></li> <li><a href="/wiki/Medical_genetics" title="Medical genetics">Medical genetics</a></li> <li><a href="/wiki/Missing_heritability_problem" title="Missing heritability problem">Missing heritability problem</a></li> <li><a href="/wiki/Molecular_evolution" title="Molecular evolution">Molecular evolution</a></li> <li><a href="/wiki/Plant_genetics" title="Plant genetics">Plant genetics</a></li> <li><a href="/wiki/Population_genomics" title="Population genomics">Population genomics</a></li> <li><a href="/wiki/Reverse_genetics" title="Reverse genetics">Reverse genetics</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Lists</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/List_of_genetic_codes" title="List of genetic codes">List of genetic codes</a></li> <li><a href="/wiki/List_of_genetics_research_organizations" title="List of genetics research organizations">List of genetics research organizations</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /> <a href="/wiki/Category:Genetics" title="Category:Genetics">Category</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Bioethics" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Medical_ethics" title="Template:Medical ethics"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Medical_ethics" title="Template talk:Medical ethics"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Medical_ethics" title="Special:EditPage/Template:Medical ethics"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Bioethics" style="font-size:114%;margin:0 4em"><a href="/wiki/Bioethics" title="Bioethics">Bioethics</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Classic principles</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Autonomy" title="Autonomy">Autonomy</a></li> <li><a href="/wiki/Beneficence_(ethics)" title="Beneficence (ethics)">Beneficence</a></li> <li><a href="/wiki/Primum_non_nocere" title="Primum non nocere">Non-maleficence</a></li> <li><a href="/wiki/Justice" title="Justice">Justice</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other principles</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Authority" title="Authority">Authority</a></li> <li><a href="/wiki/Confidentiality" title="Confidentiality">Confidentiality</a></li> <li><a href="/wiki/Conscience" title="Conscience">Conscience</a></li> <li><a href="/wiki/Principle_of_double_effect" title="Principle of double effect">Doctrine of double effect</a></li> <li><a href="/wiki/Egalitarianism" title="Egalitarianism">Equality</a></li> <li><a href="/wiki/Health_equity" title="Health equity">Equity</a></li> <li><a href="/wiki/Guilt_(emotion)" title="Guilt (emotion)">Guilt</a></li> <li><a href="/wiki/Mercy" title="Mercy">Mercy</a></li> <li><a href="/wiki/Oath" title="Oath">Oath</a></li> <li><a href="/wiki/Ownership" title="Ownership">Ownership</a></li> <li><a href="/wiki/Privacy" title="Privacy">Privacy</a></li> <li><a href="/wiki/Persuasion" title="Persuasion">Persuasion</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Theory" title="Theory">Theories</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Consequentialism" title="Consequentialism">Consequentialism</a></li> <li><a href="/wiki/Deontological_ethics" class="mw-redirect" title="Deontological ethics">Deontology</a></li> <li><a href="/wiki/Virtue_ethics" title="Virtue ethics">Virtue ethics</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Reproduction" title="Reproduction">Reproduction</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abortion" title="Abortion">Abortion</a></li> <li><a href="/wiki/Reproductive_technology" title="Reproductive technology">Reproductive technology</a></li> <li><a href="/wiki/Sex_assignment" title="Sex assignment">Gender assignment</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Genetics" title="Genetics">Genetics</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Gender" title="Gender">Gender</a></li> <li><a href="/wiki/Gene_therapy" title="Gene therapy">Gene therapy</a></li> <li><a href="/wiki/Genetic_testing" title="Genetic testing">Genetic testing</a></li> <li><a class="mw-selflink selflink">Genetic modification</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Death, dying, and emergent situations</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arbitration" title="Arbitration">Arbitration</a></li> <li><a href="/wiki/Brain_death" title="Brain death">Brain death</a></li> <li><a href="/wiki/Cardiac_death" class="mw-redirect" title="Cardiac death">Cardiac death</a></li> <li><a href="/wiki/Consensus_decision-making" title="Consensus decision-making">Consensus</a></li> <li><a href="/w/index.php?title=Court_intervention&action=edit&redlink=1" class="new" title="Court intervention (page does not exist)">Court intervention</a></li> <li><a href="/wiki/Death" title="Death">Death</a></li> <li><a href="/wiki/Ethics_committee_(disambiguation)" class="mw-disambig" title="Ethics committee (disambiguation)">Ethics committee</a></li> <li><a href="/wiki/Euthanasia" title="Euthanasia">Euthanasia</a></li> <li><a href="/wiki/Executor" title="Executor">Executor</a></li> <li><a href="/w/index.php?title=Family_meeting&action=edit&redlink=1" class="new" title="Family meeting (page does not exist)">Family meeting</a></li> <li><a href="/wiki/Mediation" title="Mediation">Mediation</a></li> <li><a href="/wiki/Next_of_kin" title="Next of kin">Next of kin</a></li> <li><a href="/wiki/Healthcare_proxy" title="Healthcare proxy">Health care proxy</a></li> <li><a href="/wiki/Suicide" title="Suicide">Suicide</a></li> <li><a href="/w/index.php?title=Transplant_ethics&action=edit&redlink=1" class="new" title="Transplant ethics (page does not exist)">Transplant ethics</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Cultural differences</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Dignity" title="Dignity">Dignity</a></li> <li><a href="/wiki/Etiquette" title="Etiquette">Etiquette</a></li> <li><a href="/wiki/Jewish_medical_ethics" title="Jewish medical ethics">Jewish medical ethics</a></li> <li><a href="/wiki/Pain" title="Pain">Pain</a></li> <li><a href="/wiki/Suffering" title="Suffering">Suffering</a></li> <li><a href="/wiki/Religion" title="Religion">Religion</a></li> <li><a href="/wiki/Respect" title="Respect">Respect</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Personal conduct</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Position_of_trust" title="Position of trust">Abuse of trust</a></li> <li><a href="/wiki/Continuity_of_care" class="mw-redirect" title="Continuity of care">Continuity of care</a></li> <li><a href="/wiki/Duty" title="Duty">Duty</a></li> <li><a href="/wiki/Gift" title="Gift">Gifts</a></li> <li><a href="/wiki/Legal_liability" title="Legal liability">Liability</a></li> <li><a href="/wiki/Lie" title="Lie">Lying</a></li> <li><a href="/wiki/Misconduct" title="Misconduct">Misconduct</a></li> <li><a href="/wiki/Scientific_misconduct" title="Scientific misconduct">Scientific misconduct</a></li> <li><a href="/w/index.php?title=Medical_misconduct&action=edit&redlink=1" class="new" title="Medical misconduct (page does not exist)">Medical misconduct</a></li> <li><a href="/wiki/Competence_(law)" title="Competence (law)">Competence (law)</a></li> <li><a href="/wiki/Competence_(human_resources)" title="Competence (human resources)">Competency</a></li> <li><a href="/wiki/Incompetency" class="mw-redirect" title="Incompetency">Incompetency</a></li> <li><a href="/w/index.php?title=Termination_of_the_patient-physician_relationship&action=edit&redlink=1" class="new" title="Termination of the patient-physician relationship (page does not exist)">Termination of the patient-physician relationship</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Research ethics</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Informed_consent" title="Informed consent">Informed consent</a></li> <li><a href="/wiki/Informed_assent" title="Informed assent">Informed assent</a></li> <li><a href="/wiki/Human_rights" title="Human rights">Human rights</a></li> <li><a href="/wiki/Institutional_review_board" title="Institutional review board">Institutional review board</a></li> <li><a href="/wiki/Human_challenge_study" title="Human challenge study">Human challenge study</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Biotechnology" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Biotechnology" title="Template:Biotechnology"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Biotechnology" title="Template talk:Biotechnology"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Biotechnology" title="Special:EditPage/Template:Biotechnology"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Biotechnology" style="font-size:114%;margin:0 4em"><a href="/wiki/Biotechnology" title="Biotechnology">Biotechnology</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">History</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/History_of_biotechnology" title="History of biotechnology">History of biotechnology</a></li> <li><a href="/wiki/Timeline_of_biotechnology" title="Timeline of biotechnology">Timeline of biotechnology</a></li> <li><a href="/wiki/Competitions_and_prizes_in_biotechnology" title="Competitions and prizes in biotechnology">Competitions and prizes in biotechnology</a></li></ul> </div></td><td class="noviewer navbox-image" rowspan="8" style="width:1px;padding:0 0 0 2px"><div><a href="/wiki/File:DNA_replication_split.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/DNA_replication_split.svg/50px-DNA_replication_split.svg.png" decoding="async" width="50" height="101" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/70/DNA_replication_split.svg/75px-DNA_replication_split.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/70/DNA_replication_split.svg/100px-DNA_replication_split.svg.png 2x" data-file-width="315" data-file-height="635" /></a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Branches</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Colors_of_biotechnology" class="mw-redirect" title="Colors of biotechnology">Colors of biotechnology</a></li> <li><a href="/wiki/Industrial_biotechnology" class="mw-redirect" title="Industrial biotechnology">Industrial biotechnology</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Biological concepts</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Allele" title="Allele">Allele</a></li> <li><a href="/wiki/Cell_(biology)" title="Cell (biology)">Cell</a></li> <li><a href="/wiki/DNA" title="DNA">DNA</a>/<a href="/wiki/RNA" title="RNA">RNA</a></li> <li><a href="/wiki/Fermentation" title="Fermentation">Fermentation</a></li> <li><a href="/wiki/Gene" title="Gene">Gene</a></li> <li><a href="/wiki/Plasmid" title="Plasmid">Plasmid</a></li> <li><a href="/wiki/Protein" title="Protein">Protein</a></li> <li><a href="/wiki/Selective_breeding" title="Selective breeding">Selective breeding</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">General concepts</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Biotechnology_industrial_park" class="mw-redirect" title="Biotechnology industrial park">Biotechnology industrial park</a></li> <li><a href="/wiki/Biotechnology_products" class="mw-redirect" title="Biotechnology products">Biotechnology products</a></li> <li><a href="/wiki/Biotechnology_law" class="mw-redirect" title="Biotechnology law">Biotechnology law</a></li> <li><a href="/wiki/Green_Revolution" title="Green Revolution">Green Revolution</a></li> <li><a href="/wiki/Human_Genome_Project" title="Human Genome Project">Human Genome Project</a></li> <li><a href="/wiki/Pharmaceutical_company" class="mw-redirect" title="Pharmaceutical company">Pharmaceutical company</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Basic techniques and tools</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Biology field</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bioreactor" title="Bioreactor">Bioreactor</a></li> <li><a href="/wiki/Cell_culture" title="Cell culture">Cell culture</a></li> <li><a href="/wiki/Cultured_meat" title="Cultured meat">Cultured meat</a></li> <li><a href="/wiki/Flow_cytometry" title="Flow cytometry">Flow cytometry</a></li> <li><a href="/wiki/Hybridoma_technology" title="Hybridoma technology">Hybridoma technology</a></li> <li><a href="/wiki/High-performance_liquid_chromatography" title="High-performance liquid chromatography">HPLC</a></li> <li><a href="/wiki/Nuclear_magnetic_resonance" title="Nuclear magnetic resonance">NMR</a></li> <li><a href="/wiki/Spectroscopy" title="Spectroscopy">Spectroscopy</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Chemical field</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Centrifugation" title="Centrifugation">Centrifugation</a></li> <li><a href="/wiki/Continuous_stirred-tank_reactor" title="Continuous stirred-tank reactor">CSTR</a></li> <li><a href="/wiki/Crystallization" title="Crystallization">Crystallization</a></li> <li><a href="/wiki/Chromatography" title="Chromatography">Chromatography</a></li> <li><a href="/wiki/Kidney_dialysis" title="Kidney dialysis">Kidney dialysis</a></li> <li><a href="/wiki/Electrophoresis" title="Electrophoresis">Electrophoresis</a></li> <li><a href="/wiki/Extraction_(chemistry)" title="Extraction (chemistry)">Extraction</a></li> <li><a href="/wiki/Fed-batch_culture" title="Fed-batch culture">Fed Batch</a></li> <li><a href="/wiki/Filtration" title="Filtration">Filtration</a></li> <li><a href="/wiki/Plug_flow_reactor_model" title="Plug flow reactor model">PFR</a></li> <li><a href="/wiki/Sedimentation" title="Sedimentation">Sedimentation</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Applications</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Animal_cell_culture" class="mw-redirect" title="Animal cell culture">Animal cell culture</a></li> <li><a href="/wiki/Biofabrication" title="Biofabrication">Biofabrication</a></li> <li><a href="/wiki/Bioinformatics" title="Bioinformatics">Bioinformatics</a></li> <li><a href="/wiki/Biosynthesis" title="Biosynthesis">Biosynthesis</a></li> <li><a href="/wiki/Bionic_architecture" title="Bionic architecture">Bionic architecture</a></li> <li><a href="/wiki/Cell_immunity" class="mw-redirect" title="Cell immunity">Cell immunity</a></li> <li><a href="/wiki/Cloning" title="Cloning">Cloning</a> <ul><li><a href="/wiki/Reproductive_cloning" class="mw-redirect" title="Reproductive cloning">Reproductive cloning</a></li> <li><a href="/wiki/Therapeutic_cloning" class="mw-redirect" title="Therapeutic cloning">Therapeutic cloning</a></li></ul></li> <li><a href="/wiki/Embryology" title="Embryology">Embryology</a></li> <li><a href="/wiki/Environmental_biotechnology" title="Environmental biotechnology">Environmental biotechnology</a></li> <li><a class="mw-selflink selflink">Genetic engineering</a> <ul><li><a href="/wiki/Genetically_modified_organism" title="Genetically modified organism">Genetically modified organism</a></li> <li><a href="/wiki/Molecular_genetics" title="Molecular genetics">Molecular genetics</a></li></ul></li> <li><a href="/wiki/Gene_therapy" title="Gene therapy">Gene therapy</a></li> <li><a href="/wiki/Microbial_biodegradation" title="Microbial biodegradation">Microbial biodegradation</a></li> <li><a href="/wiki/Omics" title="Omics">Omics</a></li> <li><a href="/wiki/Pharmacogenomics" title="Pharmacogenomics">Pharmacogenomics</a></li> <li><a href="/wiki/Stem_cells" class="mw-redirect" title="Stem cells">Stem cells</a></li> <li><a href="/wiki/Telomere" title="Telomere">Telomere</a></li> <li><a href="/wiki/Tissue_culture" title="Tissue culture">Tissue culture</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Interdisciplinary fields</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Biobased_economy" class="mw-redirect" title="Biobased economy">Bioeconomy</a></li> <li><a href="/wiki/Bioelectronics" title="Bioelectronics">Bioelectronics</a></li> <li><a href="/wiki/Biological_engineering" title="Biological engineering">Bioengineering</a></li> <li><a href="/wiki/Biology" title="Biology">Biology</a></li> <li><a href="/wiki/Biopharmaceutical" title="Biopharmaceutical">Biopharmacology</a></li> <li><a href="/wiki/Biomedical_engineering" title="Biomedical engineering">Biomedical engineering</a></li> <li><a href="/wiki/Biomedicine" title="Biomedicine">Biomedicine</a></li> <li><a href="/wiki/Biomimetics" title="Biomimetics">Biomimetics</a></li> <li><a href="/wiki/Biochemistry" title="Biochemistry">Biochemicals</a></li> <li><a href="/wiki/Biorobotics" title="Biorobotics">Biorobotics</a></li> <li><a href="/wiki/Chemical_engineering" title="Chemical engineering">Chemical engineering</a></li> <li><a href="/wiki/Microbiology" title="Microbiology">Microbiology</a></li> <li><a href="/wiki/Mining" title="Mining">Mining</a></li> <li><a href="/wiki/Molecular_biology" title="Molecular biology">Molecular biology</a></li> <li><a href="/wiki/Nanobiotechnology" title="Nanobiotechnology">Nanobiotechnology</a></li> <li><a href="/wiki/Virology" title="Virology">Virology</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Lists</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Index_of_biotechnology_articles" title="Index of biotechnology articles">Index of biotechnology articles</a></li> <li><a href="/wiki/List_of_biotechnology_articles" class="mw-redirect" title="List of biotechnology articles">List of biotechnology articles</a></li> <li><a href="/wiki/List_of_largest_biomedical_companies_by_market_capitalization" title="List of largest biomedical companies by market capitalization">List of largest biomedical companies by market capitalization</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="3"><div> <ul><li><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /> <a href="/wiki/Category:Biotechnology" title="Category:Biotechnology">Category</a></li> <li><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/12px-Commons-logo.svg.png" decoding="async" width="12" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/18px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/24px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /> <a href="https://commons.wikimedia.org/wiki/Category:Biotechnology" class="extiw" title="commons:Category:Biotechnology">Commons</a></li></ul> </div></td></tr></tbody></table></div> 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style="padding:0 0.25em"> <ul><li><a href="/wiki/3D_bioprinting" title="3D bioprinting">3D bioprinting</a> <ul><li><a href="/wiki/Microgravity_bioprinting" title="Microgravity bioprinting">Microgravity bioprinting</a></li></ul></li> <li><a href="/wiki/Aldehyde-stabilized_cryopreservation" title="Aldehyde-stabilized cryopreservation">Aldehyde-stabilized cryopreservation</a></li> <li><a href="/wiki/Ampakine" title="Ampakine">Ampakine</a></li> <li><a href="/wiki/Artificial_organ" title="Artificial organ">Artificial organs</a> <ul><li><a href="/wiki/Organ_printing" title="Organ printing">Organ printing</a></li> <li><a href="/wiki/Artificial_womb" title="Artificial womb">Womb</a></li></ul></li> <li><a href="/wiki/Biofabrication" title="Biofabrication">Biofabrication</a></li> <li><a href="/wiki/Brain_transplant" title="Brain transplant">Brain transplant</a></li> <li><a href="/wiki/De-extinction" title="De-extinction">De-extinction</a></li> <li><a href="/wiki/Generative_biology" class="mw-redirect" title="Generative biology">Generative biology</a></li> <li><a class="mw-selflink selflink">Genetic engineering</a> <ul><li><a href="/wiki/Gene_therapy" title="Gene therapy">Gene therapy</a></li></ul></li> <li><a href="/wiki/Head_transplant" title="Head transplant">Head transplant</a></li> <li><a href="/wiki/Isolated_brain" title="Isolated brain">Isolated brain</a></li> <li><a href="/wiki/Life_extension" title="Life extension">Life extension</a> <ul><li><a href="/wiki/Strategies_for_engineered_negligible_senescence" title="Strategies for engineered negligible senescence">Strategies for engineered negligible senescence</a></li></ul></li> <li><a href="/wiki/Nanomedicine" title="Nanomedicine">Nanomedicine</a></li> <li><a href="/wiki/Nanosensor" title="Nanosensor">Nanosensors</a></li> <li><a href="/wiki/Organ_culture" title="Organ culture">Organ culture</a> <ul><li><a href="/wiki/Engineered_uterus" title="Engineered uterus">engineered uterus</a></li></ul></li> <li><a href="/wiki/Personalized_medicine" title="Personalized medicine">Personalized medicine</a></li> <li><a href="/wiki/Regenerative_medicine" title="Regenerative medicine">Regenerative medicine</a> <ul><li><a href="/wiki/Stem-cell_therapy" title="Stem-cell therapy">Stem-cell therapy</a></li> <li><a href="/wiki/Tissue_engineering" title="Tissue engineering">Tissue engineering</a></li></ul></li> <li><a href="/wiki/Robot-assisted_surgery" title="Robot-assisted surgery">Robot-assisted surgery</a></li> <li><a href="/wiki/Relational_biology" class="mw-redirect" title="Relational biology">Relational biology</a></li> <li><a href="/wiki/Synthetic_biology" title="Synthetic biology">Synthetic biology</a> <ul><li><a href="/wiki/Synthetic_genomics" title="Synthetic genomics">Synthetic genomics</a></li></ul></li> <li><a href="/wiki/Medical_tricorder" title="Medical tricorder">Tricorder</a></li> <li><a href="/wiki/Virotherapy" title="Virotherapy">Virotherapy</a> <ul><li><a href="/wiki/Oncolytic_virus" title="Oncolytic virus">Oncolytic virus</a></li></ul></li> <li><a href="/wiki/Whole_genome_sequencing" title="Whole genome sequencing">Whole genome sequencing</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="text-align: center;;width:1%">Topics</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Automation" title="Automation">Automation</a></li> <li><a href="/wiki/Collingridge_dilemma" title="Collingridge dilemma">Collingridge dilemma</a></li> <li><a href="/wiki/Differential_technological_development" title="Differential technological development">Differential technological development</a></li> <li><a href="/wiki/Disruptive_innovation" title="Disruptive innovation">Disruptive innovation</a></li> <li><a href="/wiki/Ephemeralization" title="Ephemeralization">Ephemeralization</a></li> <li><a href="/wiki/Ethics_of_technology" title="Ethics of technology">Ethics</a> <ul><li><a href="/wiki/Bioethics" title="Bioethics">Bioethics</a></li> <li><a href="/wiki/Cyberethics" title="Cyberethics">Cyberethics</a></li> <li><a href="/wiki/Neuroethics" title="Neuroethics">Neuroethics</a></li> <li><a href="/wiki/Robot_ethics" title="Robot ethics">Robot ethics</a></li></ul></li> <li><a href="/wiki/Exploratory_engineering" title="Exploratory engineering">Exploratory engineering</a></li> <li><a href="/wiki/Proactionary_principle" title="Proactionary principle">Proactionary principle</a></li> <li><a href="/wiki/Technological_change" title="Technological change">Technological change</a> <ul><li><a href="/wiki/Technological_unemployment" title="Technological unemployment">Technological unemployment</a></li></ul></li> <li><a href="/wiki/Technological_convergence" title="Technological convergence">Technological convergence</a></li> <li><a href="/wiki/Technological_evolution" title="Technological evolution">Technological evolution</a></li> <li><a href="/wiki/Technological_paradigm" title="Technological paradigm">Technological paradigm</a></li> <li><a href="/wiki/Technology_forecasting" title="Technology forecasting">Technology forecasting</a> <ul><li><a href="/wiki/Accelerating_change" title="Accelerating change">Accelerating change</a></li> <li><a href="/wiki/Future-oriented_technology_analysis" title="Future-oriented technology analysis">Future-oriented technology analysis</a></li> <li><a href="/wiki/Horizon_scanning" title="Horizon scanning">Horizon scanning</a></li> <li><a href="/wiki/Moore%27s_law" title="Moore's law">Moore's law</a></li> <li><a href="/wiki/Technological_singularity" title="Technological singularity">Technological singularity</a></li> <li><a href="/wiki/Technology_scouting" title="Technology scouting">Technology scouting</a></li></ul></li> <li><a href="/wiki/Technology_in_science_fiction" title="Technology in science fiction">Technology in science fiction</a></li> <li><a href="/wiki/Technology_readiness_level" title="Technology readiness level">Technology readiness level</a></li> <li><a href="/wiki/Technology_roadmap" title="Technology roadmap">Technology roadmap</a></li> <li><a href="/wiki/Transhumanism" title="Transhumanism">Transhumanism</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="text-align: center;"><div> <ul><li><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/d/db/Symbol_list_class.svg/16px-Symbol_list_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/d/db/Symbol_list_class.svg/23px-Symbol_list_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/d/db/Symbol_list_class.svg/31px-Symbol_list_class.svg.png 2x" data-file-width="180" data-file-height="185" /> <a href="/wiki/List_of_emerging_technologies" title="List of emerging technologies">List</a></li></ul> </div></td></tr></tbody></table></div> <style 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