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id="content" class="wrapper main"> <div class="wrap"> <div class="publications-filter filters"> <h2 class="filter-header">Filter By:</h2> <div class="select-container"> <div class="select-wrap"> <select id="companies" name="company" class="select-area"> <option value="all">All Companies</option> <option value="20">Comparative Biosciences, Inc.</option> <option value="32">Institute of Metabolic Disorders</option> <option value="18">Invivotek</option> <option value="26">Medical Diagnostic Laboratories</option> <option value="14">New England Discovery Partners</option> <option value="19">NexusPharma</option> <option value="31">Oncoveda</option> <option value="17">PharmOptima</option> <option value="13">VENENUM Biodesign</option> </select> </div> <div class="select-wrap"> <select id="year" name="year" class="select-area"> <option value="all">Every Year</option> <option value="2024">2024</option> <option value="2023">2023</option> <option value="2022">2022</option> <option 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class="tab-line"></div> </div> <ul id="research" class="tab-articles long-article display-tab text-normal pub_list"> <li class="tab-container inline-block" data-company="20" data-year="2024" data-type="Original Research Papers"> Selitrennikoff CP, Sylvia C, Sanchez M, Lawrence P, Trosch K, Carenza A, Meschter C. 2024. Evaluate the safety of a novel photohydrolysis technology used to clean and disinfect indoor air: A murine study. PLoS One. 19(10):e0307031. <a href="https://pubmed.ncbi.nlm.nih.gov/39383125/" target="_blank" class="tab_link">PMID: 39383125</a> </li><li class="tab-container inline-block" data-company="17" data-year="2023" data-type="Original Research Papers"> Somasundaram P, Farley MM, Rudy MA, Stefanoff DG, Shah M, Goli P, Heo J, Wang S, Tran NM, Watkins TA. 2023. Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by Atf4 following optic nerve injury. eLife [Preprint].:2023.03.29.534798. doi: 10.1101/2023.03.29.534798 <a href="https://pubmed.ncbi.nlm.nih.gov/37034690/" target="_blank" class="tab_link">PMID: 37034690</a> </li><li class="tab-container inline-block" data-company="18" data-year="2022" data-type="Original Research Papers"> Donthireddy L, Vonteddu P, Murthy T, Kwak T, Eraslan R, Podojil JR, Elhofy A, Boyne MT, Puisis JJ, Veglia F, Singh SS, Dotiwala F, Montaner LJ, Gabrilovich DI. 2022. ONP-302 Nanoparticles Inhibit Tumor Growth By Altering Tumor-Associated Macrophages And Cancer-Associated Fibroblasts. J Cancer 28;13(6):1933-1944 (2022) <a href="https://pubmed.ncbi.nlm.nih.gov/35399717/" target="_blank" class="tab_link">PMID: 35399717</a> </li><li class="tab-container inline-block" data-company="17" data-year="2022" data-type="Original Research Papers"> Zaworski PG, Schwartz R, Burr J, Skutnik D, Mollin A, Kumar B, Ngumah Q, Welch E, Johnson B, Narasimhan J, Weetall M. 2022. Quantitation of Pax-6 protein in ocular impression cytology samples using an electrochemiluminescence immunoassay. Anal Biochem 1;656:114876. Epub 2022 Sep 2. <a href="https://pubmed.ncbi.nlm.nih.gov/36058293/" target="_blank" class="tab_link">PMID: 36058293</a> </li><li class="tab-container inline-block" data-company="18" data-year="2022" data-type="Original Research Papers"> Karla K. Frietze, Alyssa M. Brown, Dividutta Das, Raymond G. Franks, Jessie Lee Cunningham, Michael Hayward, Joseph T. Nickels. 2022. Lipotoxicity reduces Rig-1 expression and activity leading to impaired autophagy and cell death. Autophagy, 2022, VOL. 18, NO. 1, 142–160 https://doi.org/10.1080/15548627.2021.1920818 </li><li class="tab-container inline-block" data-company="17" data-year="2021" data-type="Original Research Papers"> Maillet E, Skutnik D, Jamison JA, Bailey D, Bacellar-Galdino M, & Garlick D. 2021. 2021. Anti-Inflammatory and Protective Effects of Topical Opthlamic (R)-DOI 0.01% in Allergic Conjunctivitis and Recurrent Intermediate Uveitis Disease Models in Rabbits. IOVS June 2021. 62, 232. </li><li class="tab-container inline-block" data-company="18" data-year="2021" data-type="Original Research Papers"> Gupta, A., Gullapalli, S., Pan, H. Ramos-Ortolaza, D. L., Hayward, M.D., Low, M.J. Pintar, J.E. Devi, L.A. I. 2021. Gomes Regulation of Opioid Receptors by Their Endogenous Opioid Peptides. Cell Mol Neurobiol 2021 July ; 41(5): 1103–1118. https://doi.org/10.1007%2Fs10571-020-01015-w </li><li class="tab-container inline-block" data-company="17" data-year="2020" data-type="Original Research Papers"> Christiano R. R. Alves PhD1, Ren Zhang MPH1, Alec J. Johnstone BS1, Reid Garner BS1, Eric J. Eichelberger BS1, Salomé Da Silva Duarte Lepez BA1, Vivian Yi BS1, Victoria Stevens B.S.1, Rebekah Poxson BA2, Rachel Schwartz BA2, Phillip Zaworski MS2, Kathryn J. Swoboda. 2020. MD1 Whole blood survival motor neuron protein levels correlate with severity of denervation in spinal muscular atrophy Muscle and Nerve DOI: 10.1002/mus.26995 2020 In Press </li><li class="tab-container inline-block" data-company="19" data-year="2020" data-type="Original Research Papers"> Gabitova-Cornell L, Surumbayeva A, Peri S, Franco-Barraza J, Restifo D, Weitz N, Ogier C, Goldman AR, Hartman TR, Francescone R, Tan Y, Nicolas E, Shah N, Handorf EA, Cai KQ, O'Reilly AM, Sloma I, Chiaverelli R, Moffitt RA, Khazak V, Fang CY, Golemis EA, Cukierman E, Astsaturov I. 2020. Cholesterol Pathway Inhibition Induces TGF-? Signaling to Promote Basal Differentiation in Pancreatic Cancer. Cancer Cell 38(4):567-583. e11. doi: 10.1016/j.ccell.2020.08.015. Epub 2020 Sep 24 <a href="https://pubmed.ncbi.nlm.nih.gov/32976774/" target="_blank" class="tab_link">PMID: 32976774</a> </li><li class="tab-container inline-block" data-company="19" data-year="2020" data-type="Original Research Papers"> Makhov P, Sohn JA, Serebriiskii IG, Fazliyeva R, Khazak V, Boumber Y, Uzzo RG, Kolenko VM. 2020. CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma. Br J Cancer Sep 24. doi: 10.1038/s41416-020-01087-x. Online ahead of print. </li><li class="tab-container inline-block" data-company="18" data-year="2020" data-type="Original Research Papers"> Muhua Yang, Christina Gallo-Ebert, Michael Hayward, Weidong Liu, Virginia McDonough and Joseph T. Nickels, Jr. 2020. Human insulin growth factor 2 mRNA binding protein 2 increases miR-33a/b inhibition of liver ABCA1 expression and alters low-density apolipoprotein levels in mice Mol and Cell Biol. 2020 Aug; 40(16): e00058-20. DIO: https://doi.org/10.1128%2FMCB.00058-20 </li><li class="tab-container inline-block" data-company="17" data-year="2019" data-type="Original Research Papers"> Ramos DM, d'Ydewalle C, Gabbeta V, Dakka A, Klein SK, Norris DA, Matson J, Taylor SJ, Zaworski PG, Prior TW, Snyder PJ, Valdivia D, Hatem CL, Waters I, Gupte N, Swoboda KJ, Rigo F, Bennett CF, Naryshkin N, Paushkin S, Crawford TO, Sumner CJ. 2019. Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. Clin Invest https://doi.org/10.1172/JCI124120. [Epub ahead of print] <a href="https://pubmed.ncbi.nlm.nih.gov/31589162/" target="_blank" class="tab_link">PMID: 31589162</a> </li><li class="tab-container inline-block" data-company="14" data-year="2019" data-type="Original Research Papers"> Michael C. Van Zandt, G. Erik Jagdmann, Darren L. Whitehouse, Minkoo Ji, Jennifer Savoy, Olga Potapova, Alexandra Cousido-Siah, Andre Mitschler, Eduardo I. Howard, Anna Marie Pyle, and Alberto D. Podjarny. 2019. Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II </li><li class="tab-container inline-block" data-company="18" data-year="2018" data-type="Original Research Papers"> Gallo-Ebert C, Francisco J, Liu HY, Draper R, Modi K, Hayward MD, Jones BK, Buiakova O, McDonough V, Nickels, JT Jr. 2018. Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease. J Biol Chem 296(16): 5956-5974 2018 </li><li class="tab-container inline-block" data-company="13" data-year="2018" data-type="Original Research Papers"> Stroke, IL, Letourneau, JJ, Miller, TE, Xu, Y, Pechik, I, Savoly, DR, Ma, L, Sturzenbecker, LJ, Sabalski, J, Stein, PD, Webb, ML, Hilbert, DW. 2018. Treatment of Clostridium difficile infection with a small molecule inhibitor of toxin UDP-glucose hydrolysis activity. Antimicrob. Agents Chemother. (2018), 62, e00107-18 </li><li class="tab-container inline-block" data-company="13" data-year="2018" data-type="Original Research Papers"> Letourneau, JJ, Stroke, IL, Hilbert, DW, Sturzenbecker, LJ, Marinelli, BA, Quintero, JG, Sabalski, J, Ma, L, Diller, DJ, Stein, PD, Webb, ML. 2018. Identification and initial optimization of inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB). Bioorganic & Medicinal Chemistry Letters (2018), 28(4), 756-7 </li><li class="tab-container inline-block" data-company="17" data-year="2018" data-type="Original Research Papers"> Strathmann EA, Peters M, Hosseinibarkooie S, Rigo FW, Bennett CF, Zaworski PG, Chen KS, Nothnagel M. 2018. Wirth B. Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice. PLoS One. 2018 Sep 6;13(9):e0203398. doi: 10.1371/journal.pone.0203398. eCollection </li><li class="tab-container inline-block" data-company="17" data-year="2018" data-type="Original Research Papers"> Iyer CC, Corlett KM, Massoni-Laporte A, Duque SI, Madabusi N, Tisdale S, McGovern VL, Le TT, Zaworski PG, Arnold WD, Pellizzoni L, Burghes. 2018. Mild SMN missense alleles are only functional in the presence of SMN2 in mammals. AHM.Hum Mol Genet. 2018 Oct 1;27(19):3404-3416. doi: 10.1093/hmg/ddy251 <a href="https://pubmed.ncbi.nlm.nih.gov/29982416/" target="_blank" class="tab_link">PMID: 29982416</a> </li><li class="tab-container inline-block" data-company="17" data-year="2018" data-type="Original Research Papers"> Decker DE, Skutnik D, Burr J, Pattison C, Cooley-Themm C, Linn DM, & Linn CL. 2018. 2018. GDF-15 Levels increase in Aqueous Humor Following Hypertonic Saline Injection into the Episcleral Vein in a Rat Claucoma Model. IOVS July 2018. 59, 3504. </li><li class="tab-container inline-block" data-company="18" data-year="2018" data-type="Original Research Papers"> Lisa D Berman-Booty , Rukiye Eraslan, Umesh Hanumegowda, Glenn H Cantor , Denise I Bounous , Evan B Janovitz, Beverly K Jones , Olesia Buiakova, Michael Hayward, Susan Wee. 2018. Systemic Loss of C-terminal Src Kinase (CSK) Expression Elicits Spontaneous Suppurative Inflammation in Conditional Knockout Mice. Vet Pathol 2018 Mar;55(2):331-340 </li><li class="tab-container inline-block" data-company="14" data-year="2018" data-type="Original Research Papers"> Fedorova, Olga; Jagdmann, G. Erik; Adams, Rebecca L.; Yuan, Lin; Van Zandt, Michael; Pyle, Anna Marie . 2018. Small molecules that target group II introns are potent antifungal agents, Nature Chemical Biology (2018), 14 (12), 1073-1078 <a href="https://pubmed.ncbi.nlm.nih.gov/30323219/" target="_blank" class="tab_link">PMID: 30323219</a> </li><li class="tab-container inline-block" data-company="14" data-year="2018" data-type="Original Research Papers"> Van Zandt, Michael C.; Savoy, Jennifer L.. 2018. Method of preparing (3r,4s)-3-acetamido-4-allyl-n-(tert-butyl) pyrrolidine-3-carboxamide, WO 2018209290 A1, 60 pp (2018) </li><li class="tab-container inline-block" data-company="14" data-year="2018" data-type="Original Research Papers"> Dworak, Jessica; Jagdmann, G. Erik; Van Zandt, Michael. 2018. Total synthesis of protectin DX, a potent proresolving lipid mediator, Abstracts of Papers, 256th ACS National Meeting & Exposition, Boston, MA, United States, August 19-23, 2018 (2018), ORGN-648 </li><li class="tab-container inline-block" data-company="14" data-year="2018" data-type="Original Research Papers"> Rinis, Natalia; Golden, Jennifer E.; Marceau, Caleb D.; Carette, Jan E.; Van Zandt, Michael C.; Gilmore, Reid; Contessa, Joseph N. 2018. Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors, Cell Chemical Biology (2018), 25(10), 1231-1241.e4 <a href="https://pubmed.ncbi.nlm.nih.gov/30078634/" target="_blank" class="tab_link">PMID: 30078634</a> </li><li class="tab-container inline-block" data-company="14" data-year="2018" data-type="Original Research Papers"> Sjogren, Eric B.; Li, Jim; Chen, Lijing; Billedeau, Roland J.; Stanton, Timothy F.; Van Zandt, Michael; Whitehouse, Darren; Jagdmann, Gunnar E., Jr.; Petersen, Lene Raunkjaer; Parlati, Francesco; et al. 2018. Preparation of boron compounds and using compositions and methods for inhibiting arginase activity, WO 2018119440 A1, 220 pp (2018) </li><li class="tab-container inline-block" data-company="14" data-year="2018" data-type="Original Research Papers"> Sciavolino, Frank C.; Mathias, Gary; Van Zandt, Michael; Jagdmann, G. Erik; Dworak, Jessica. 2018. Compositions and methods relating to salts of specialized pro-resolving mediators of inflammation, WO 2017210604 A1, 109 pp (2018) </li><li class="tab-container inline-block" data-company="14" data-year="2018" data-type="Original Research Papers"> Gopinath, Smita; Kim, Myoungjoo V.; Rakib, Tasfia; Wong, Patrick W.; van Zandt, Michael; Barry, Natasha A.; Kaisho, Tsuneyasu; Goodman, Andrew L.; Iwasaki, Akiko. 2018. Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner, Nature Microbiology (2018), 3(5), 611-621 <a href="https://pubmed.ncbi.nlm.nih.gov/29632368/" target="_blank" class="tab_link">PMID: 29632368</a> </li><li class="tab-container inline-block" data-company="18" data-year="2017" data-type="Original Research Papers"> He S, Gleason J, Fik-Rymarkiewicz E, DiFiglia A, Bharathan M, Morschauser A, Djuretic I, Xu Y, Krakovsky M, Jankovic V, Buensuceso C, Edinger J, Herzberg U, Hofgartner W, Hariri R. 2017. Human Placenta-Derived Mesenchymal Stromal-Like Cells Enhance Angiogenesis via T Cell-Dependent Reprogramming of Macrophage Differentiation. Stem Cells 35(6): 1603-1613 <a href="https://pubmed.ncbi.nlm.nih.gov/28233380/" target="_blank" class="tab_link">PMID: 28233380</a> </li><li class="tab-container inline-block" data-company="17" data-year="2017" data-type="Original Research Papers"> Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Iannaccone ST, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AHM, Bartlett A, Kissel JT. 2017. NeuroNEXT Clinical Trial Network on behalf of the NN101 SMA Biomarker Investigators. Natural history of infantile-onset spinal muscular atrophy. Ann Neurol. 2017 Dec;82(6):883-891. doi: 10.1002/ana.25101. Epub 2017 Dec 8. Free PMC article. Clinical Trial. </li><li class="tab-container inline-block" data-company="14" data-year="2017" data-type="Original Research Papers"> Sjogren, Eric B.; Li, Jim; Van Zandt, Michael; Whitehouse, Darren. . 2017. Compositions and methods for inhibiting arginase activity, WO 2017075363 A1, 54 pp (2017) </li><li class="tab-container inline-block" data-company="17" data-year="2016" data-type="Original Research Papers"> Zaworski P, von Herrmann KM, Taylor S, Sunshine SS, McCarthy K, Risher N, Newcomb T, Weetall M, Prior TW, Swoboda KJ, Chen KS, Paushkin S. 2016. SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials PLoS ONE 11(3): e0150640. <a href="https://pubmed.ncbi.nlm.nih.gov/26953792/" target="_blank" class="tab_link">PMID: 26953792</a> </li><li class="tab-container inline-block" data-company="17" data-year="2016" data-type="Original Research Papers"> Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Iannaccone ST, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AHM, Bartlett A, Kissel JT, and the NeuroNEXT Clinical Trial Network and on behalf of the NN101 SMA Biomarker Investigators. 2016. Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study. Ann Clin Transl Neurol 3(2): 132-145. <a href="https://pubmed.ncbi.nlm.nih.gov/26900585/" target="_blank" class="tab_link">PMID: 26900585</a> </li><li class="tab-container inline-block" data-company="19" data-year="2016" data-type="Original Research Papers"> Gaponova AV, Nikonova AS, Deneka A, Kopp MC, Kudinov AE, Skobeleva N, Khazak V, Ogawa LS, Cai KQ, Duncan KE, Duncan JS, Egleston BL, Proia DA, Boumber Y, Golemis EA. 2016. A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer. Clin Cancer Res. 2016 Oct 15;22(20):5120-5129. doi: 10.1158/1078-0432.CCR-15-3068. </li><li class="tab-container inline-block" data-company="17" data-year="2016" data-type="Original Research Papers"> Kolb, SJ, Coffey, CS, Yankey, JW et al. 2016. Baseline results of the NeuroNext spinal muscular atrophy infant biomarker study. Annals of Clinical and Translational Neurology, 21 January 2016;1-14 </li><li class="tab-container inline-block" data-company="17" data-year="2016" data-type="Original Research Papers"> Arnold WD, Duque S, Iyer CC, Zaworski P, McGovern VL, Taylor SJ, von Herrmann KM, Kobayashi DT, Chen KS, Kolb SJ, Paushkin SV, Burghes AH. 2016. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration. PLoS One. 2016 Dec 1;11(12):e0167077. doi: 10.1371/journal.pone.0167077. eCollection 2016. <a href="https://pubmed.ncbi.nlm.nih.gov/27907033/" target="_blank" class="tab_link">PMID: 27907033</a> </li><li class="tab-container inline-block" data-company="32" data-year="2016" data-type="Original Research Papers"> Villasmil, M. L., J. Francisco, C. Gallo-Ebert, M. Donigan, H. Y. Liu, M. Brower, and J. T. Nickels, Jr. 2016. Ceramide signals for initiation of yeast mating-specific cell cycle arrest. 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Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo [2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications, Bioorganic & Medicinal Chemistry Letters (2009), 19(7), 2006-2008 </li><li class="tab-container inline-block" data-company="19" data-year="2008" data-type="Original Research Papers"> Campbell PM, Lee KM, Ouellette MM, Kim HJ, Groehler AL, Khazak V, Der CJ. 2008. Ras-driven transformation of human nestin-positive pancreatic epithelial cells. Methods Enzymol;439:451-65. doi: 10.1016/S0076-6879(07)00431-4. </li><li class="tab-container inline-block" data-company="19" data-year="2008" data-type="Original Research Papers"> Rothweiler U, Czarna A, Krajewski M, Ciombor J, Kalinski C, Khazak V, Ross G, Skobeleva N, Weber L, Holak TA. 2008. Isoquinolin-1-one inhibitors of the MDM2-p53 interaction. ChemMedChem. 2008 Jul;3(7):1118-28. doi: 10.1002/cmdc.200800025. </li><li class="tab-container inline-block" data-company="26" data-year="2008" data-type="Original Research Papers"> Gygax SE, Vermitsky JP, Self MJ, Mordechai E, Adelson ME, Trama JP. 2008. Antifungal resistance in vaginal Candida clinical isolates. Antimicrob Agents Chemother, manuscript under review <a href="https://pubmed.ncbi.nlm.nih.gov/18591262/" target="_blank" class="tab_link">PMID: 18591262</a> </li><li class="tab-container inline-block" data-company="26" data-year="2008" data-type="Original Research Papers"> Hilbert DW, Paulish TE, Mordechai E, Adelson ME, and Trama JP. 2008. O serogroups, phylogeny, and virulence factors of cervicovaginal and rectal Escherichia coli isolates. Eur J Clin Microb Infect Dis. 27(12): 1265-8 <a href="https://pubmed.ncbi.nlm.nih.gov/18584221/" target="_blank" class="tab_link">PMID: 18584221</a> </li><li class="tab-container inline-block" data-company="26" data-year="2008" data-type="Original Research Papers"> Libby EK, Pascal KE, Mordechai E, Adelson ME, Trama JP. 2008. Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis. Microb Infect, 10(4):439-446 <a href="https://pubmed.ncbi.nlm.nih.gov/18403235/" target="_blank" class="tab_link">PMID: 18403235</a> </li><li class="tab-container inline-block" data-company="26" data-year="2008" data-type="Original Research Papers"> Hilbert DW, Pascal KE, Libby EK, Mordechai E, Adelson ME, Trama JP. 2008. Uropathogenic Escherichia coli dominantly suppresses the innate immune response of bladder epithelial cells by a lipopolysaccharide- and Toll-like receptor 4-independent pathway. Microb Infect, 10(2):114-21 <a href="https://pubmed.ncbi.nlm.nih.gov/18248759/" target="_blank" class="tab_link">PMID: 18248759</a> </li><li class="tab-container inline-block" data-company="26" data-year="2008" data-type="Original Research Papers"> Trama JP, Pascal KE, Zimmerman JA, Self MJ, Mordechai E, Adelson ME. 2008. Rapid detection of Atopobium vaginae and association with organisms implicated in bacterial vaginosis. Mol Cell Probes, 22(2):96-102 <a href="https://pubmed.ncbi.nlm.nih.gov/17913456/" target="_blank" class="tab_link">PMID: 17913456</a> </li><li class="tab-container inline-block" data-company="26" data-year="2008" data-type="Original Research Papers"> McCool TL, Hoey JG, Montileone F, Goldenberg HB, Mordechai E, Adelson ME. 2008. Discovery and analysis of Bartonella henselae antigens for use in clinical serological assays. Diagn Microbiol Infect Dis, 60(1):17-23 <a href="https://pubmed.ncbi.nlm.nih.gov/17889484/" target="_blank" class="tab_link">PMID: 17889484</a> </li><li class="tab-container inline-block" data-company="19" data-year="2007" data-type="Original Research Papers"> Khazak V, Astsaturov I, Serebriiskii IG, Golemis EA. 2007. Selective Raf inhibition in cancer therapy. Expert Opin Ther Targets;11(12):1587-609. Review. Erratum in: Expert Opin Ther Targets. 2009 Sep;13(9):1135. </li><li class="tab-container inline-block" data-company="19" data-year="2007" data-type="Original Research Papers"> Hao H, Muniz-Medina VM, Mehta H, Thomas NE, Khazak V, Der CJ, Shields JM. 2007. Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth. Mol Cancer Ther;6(8):2220-9. </li><li class="tab-container inline-block" data-company="19" data-year="2007" data-type="Original Research Papers"> Popowicz GM, Czarna A, Rothweiler U, Szwagierczak A, Krajewski M, Weber L, Holak TA. 2007. Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle;6(19):2386-92. </li><li class="tab-container inline-block" data-company="19" data-year="2007" data-type="Original Research Papers"> Skobeleva N, Menon S, Weber L, Golemis EA, Khazak V. 2007. In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway- and microtubule-targeting inhibitors. Mol Cancer Ther;6(3):898-906. </li><li class="tab-container inline-block" data-company="19" data-year="2007" data-type="Original Research Papers"> Campbell PM, Groehler AL, Lee KM, Ouellette MM, Khazak V, Der CJ. 2007. K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling. Cancer Res;67(5):2098-106. </li><li class="tab-container inline-block" data-company="31" data-year="2007" data-type="Original Research Papers"> Huang LP, Lyu SC, Clayberger C, Krensky AM. 2007. Granulysin-mediated tumor rejection in transgenic mice. J Immunol. 2007 Jan 1; 178(1):77-84 <a href="https://pubmed.ncbi.nlm.nih.gov/17182542/" target="_blank" class="tab_link">PMID: 17182542</a> </li><li class="tab-container inline-block" data-company="26" data-year="2007" data-type="Original Research Papers"> Vermitsky JP, Self MJ, Chadwick SG, Trama JP, Mordechai E, Adelson ME. 2007. A survey of vaginal flora Candida species isolates from women of different age groups by use of species-specific PCR detection. J Clin Microbiol, 46(4):1501-1503 <a href="https://pubmed.ncbi.nlm.nih.gov/18305136/" target="_blank" class="tab_link">PMID: 18305136</a> </li><li class="tab-container inline-block" data-company="26" data-year="2007" data-type="Original Research Papers"> Gygax SE, Schuyler JA, Trama JP, Mordechai E, Adelson ME. 2007. The detection of erythromycin and clindamycin resistance genes in both Group B Streptococcal clinical isolates and cervicovaginal/rectal swabs. Microb Drug Resist, 13(2):119-123 <a href="https://pubmed.ncbi.nlm.nih.gov/17650964/" target="_blank" class="tab_link">PMID: 17650964</a> </li><li class="tab-container inline-block" data-company="26" data-year="2007" data-type="Original Research Papers"> Trama JP, Pascal KE, Zimmerman JA, Self MJ, Mordechai E, Adelson ME. 2007. Identification and genotyping of Molluscum Contagiosum virus from genital swab samples by Real-Time PCR and Pyrosequencing. J Clin Virol, 40(4):325-329 <a href="https://pubmed.ncbi.nlm.nih.gov/17997134/" target="_blank" class="tab_link">PMID: 17997134</a> </li><li class="tab-container inline-block" data-company="26" data-year="2006" data-type="Original Research Papers"> Gygax SE, Schuyler JA, Kimmel LE, Trama JP, Mordechai E, Adelson, ME. 2006. Erythromycin and clindamycin resistance in Group B Streptococcal clinical isolates. Antimicrob Agents Chemother, 50(5):1875-7 <a href="https://pubmed.ncbi.nlm.nih.gov/16641466/" target="_blank" class="tab_link">PMID: 16641466</a> </li><li class="tab-container inline-block" data-company="26" data-year="2006" data-type="Original Research Papers"> Loa CC, Mordechai E, Tilton RC, Adelson ME. 2006. Production of recombinant Bartonella henselae 17 kDa protein for antibody-capture enzyme-linked immunosorbent assay. Diagn Microbiol Infect Dis, 55(1):1-7 <a href="https://pubmed.ncbi.nlm.nih.gov/16490335/" target="_blank" class="tab_link">PMID: 16490335</a> </li><li class="tab-container inline-block" data-company="26" data-year="2006" data-type="Original Research Papers"> Meer-Scherrer L, Adelson ME, Mordechai E, Tilton RC. 2006. Neuroborreliosis associated with Alzheimer’s disease. Curr Microbiol, 52(4):330-2 <a href="https://pubmed.ncbi.nlm.nih.gov/16528463/" target="_blank" class="tab_link">PMID: 16528463</a> </li><li class="tab-container inline-block" data-company="19" data-year="2005" data-type="Original Research Papers"> Khazak V, Golemis EA, Weber L. 2005. Development of a yeast two-hybrid screen for selection of human Ras-Raf protein interaction inhibitors. Methods Mol Biol. 310:253-71. </li><li class="tab-container inline-block" data-company="19" data-year="2005" data-type="Original Research Papers"> Weber L. 2005. Chemistry for chemical genomics. Methods Mol Biol. 2005;310:11-24. </li><li class="tab-container inline-block" data-company="26" data-year="2005" data-type="Original Research Papers"> Trama JP, Adelson ME, Raphaelli I, Mordechai E. 2005. Detection of Candida species in vaginal samples in a clinical laboratory setting. Infect Dis Obstet Gynecol, 13(2):63-7 <a href="https://pubmed.ncbi.nlm.nih.gov/16011995/" target="_blank" class="tab_link">PMID: 16011995</a> </li><li class="tab-container inline-block" data-company="26" data-year="2005" data-type="Original Research Papers"> Trama JP, Mordechai E, Adelson ME. 2005. Detection and identification of Candida species associated with candida vaginitis by Real- Time PCR and Pyrosequencing. Mol Cell Probes, 19(2):145-52 <a href="https://pubmed.ncbi.nlm.nih.gov/15680216/" target="_blank" class="tab_link">PMID: 15680216</a> </li><li class="tab-container inline-block" data-company="26" data-year="2005" data-type="Original Research Papers"> Trama JP, Mordechai E, Adelson ME. 2005. Detection of Aspergillus fumigatus and a mutation that confers reduced susceptibility to itraconazole and posaconazole by Real-Time PCR and Pyrosequencing. J Clin Microbiol. 43(2):906-8 <a href="https://pubmed.ncbi.nlm.nih.gov/15695702/" target="_blank" class="tab_link">PMID: 15695702</a> </li><li class="tab-container inline-block" data-company="26" data-year="2005" data-type="Original Research Papers"> Drisko J, Bischoff B, Giles C, Adelson ME, Rao RV, McCallum R. 2005. Evaluation of 5 probiotic products for bacteria by DNA extraction and PCR analysis. Dig Dis Sci, 50(6):1113-7 <a href="https://pubmed.ncbi.nlm.nih.gov/15986864/" target="_blank" class="tab_link">PMID: 15986864</a> </li><li class="tab-container inline-block" data-company="26" data-year="2005" data-type="Original Research Papers"> Adelson ME, Feola M, Trama JP, Tilton RC, Mordechai E. 2005. Simultaneous detection of herpes simplex virus types 1 and 2 by Real-Time PCR and Pyrosequencing. J Clin Virol, 33(1):25-34 <a href="https://pubmed.ncbi.nlm.nih.gov/15797362/" target="_blank" class="tab_link">PMID: 15797362</a> </li><li class="tab-container inline-block" data-company="14" data-year="2005" data-type="Original Research Papers"> Van Zandt, Michael C.; Jones, Michael L.; Gunn, David E.; Geraci, Leo S.; Jones, J. Howard; Sawicki, Diane R.; Sredy, Janet; Jacot, Jorge L.; DiCioccio, A. Thomas; Petrova, Tatiana; et al. 2005. Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole- N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications, Journal of Medicinal Chemistry (2005), 48(9), 3141-3152 <a href="https://pubmed.ncbi.nlm.nih.gov/15857120/" target="_blank" class="tab_link">PMID: 15857120</a> </li><li class="tab-container inline-block" data-company="19" data-year="2004" data-type="Original Research Papers"> Lu Y, Sakamuri S, Chen QZ, Keng YF, Khazak V, Illgen K, Schabbert S, Weber L, Menon SR. 2004. Solution phase parallel synthesis and evaluation of MAPK inhibitory activities of close structural analogues of a Ras pathway modulator. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3957-62. </li><li class="tab-container inline-block" data-company="26" data-year="2004" data-type="Original Research Papers"> Adelson ME, Rao RV, Tilton RC, Cabets K, Eskow E, Fein L, Occi JL, Mordechai E. 2004. Prevalence of Borrelia burgdorferi, Bartonella species, Babesia microti, and Anaplasma phagocytophila in Ixodes scapularis collected in northern New Jersey. J Clin Microbiol, 42:2799-2801 <a href="https://pubmed.ncbi.nlm.nih.gov/15184475/" target="_blank" class="tab_link">PMID: 15184475</a> </li><li class="tab-container inline-block" data-company="26" data-year="2004" data-type="Original Research Papers"> Meer-Scherrer L, Adelson ME, Mordechai E, Lottaz B, Tilton RC. 2004. Babesia microti infection in Europe. Curr Microbiol, 48(6):435-7 <a href="https://pubmed.ncbi.nlm.nih.gov/15170239/" target="_blank" class="tab_link">PMID: 15170239</a> </li><li class="tab-container inline-block" data-company="26" data-year="2004" data-type="Original Research Papers"> Mogilyansky E, Loa CC, Adelson ME, Mordechai E, Tilton RC. 2004. Comparison of western immunoblots and the C6 Lyme antibody test for the laboratory detection of Lyme disease. Clin Diagn Lab Immunol, 11(5):924-929 <a href="https://pubmed.ncbi.nlm.nih.gov/15358654/" target="_blank" class="tab_link">PMID: 15358654</a> </li><li class="tab-container inline-block" data-company="26" data-year="2004" data-type="Original Research Papers"> Loa CC, Adelson ME, Mordechai E, Raphaelli I, Tilton RC. 2004. Serological diagnosis of human babesiosis by IgG enzyme-linked immunoabsorbent assay. Curr Microbiol, 49:385-389 <a href="https://pubmed.ncbi.nlm.nih.gov/15696612/" target="_blank" class="tab_link">PMID: 15696612</a> </li><li class="tab-container inline-block" data-company="14" data-year="2004" data-type="Original Research Papers"> Van Zandt, Michael C.; Sibley, Evelyn O.; McCann, Erin E.; Combs, Kerry J.; Flam, Brenda; Sawicki, Diane R.; Sabetta, Al; Carrington, Anne; Sredy, Janet; Howard, Eduardo; et al. 2004. Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications, Bioorganic & Medicinal Chemistry Letters (2004), 12(21), 5661-5675 <a href="https://pubmed.ncbi.nlm.nih.gov/15465344/" target="_blank" class="tab_link">PMID: 15465344</a> </li><li class="tab-container inline-block" data-company="26" data-year="2003" data-type="Original Research Papers"> Eskow E, Adelson ME, Rao RV, Mordechai E. 2003. Evidence for disseminated Mycoplasma fermentans in New Jersey residents with antecedent tick attachment and subsequent musculoskeletal symptoms. J Clin Rheumatol, 9:77-87 <a href="https://pubmed.ncbi.nlm.nih.gov/17041434/" target="_blank" class="tab_link">PMID: 17041434</a> </li><li class="tab-container inline-block" data-company="26" data-year="2003" data-type="Original Research Papers"> Tilton RC. 2003. New tests for Lyme disease. Clin Microbiol Newsl, 25(19):145-149 </li><li class="tab-container inline-block" data-company="19" data-year="2002" data-type="Original Research Papers"> Kato-Stankiewicz J, Hakimi I, Zhi G, Zhang J, Serebriiskii I, Guo L, Edamatsu H, Koide H, Menon S, Eckl R, Sakamuri S, Lu Y, Chen QZ, Agarwal S, Baumbach WR, Golemis EA, Tamanoi F, Khazak V. 2002. Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14398-403. </li><li class="tab-container inline-block" data-company="26" data-year="2001" data-type="Original Research Papers"> Eskow E, Rao RV, Mordechai E. 2001. Concurrent infection of the central nervous system by Borrelia burgdorferi and Bartonella henselae: Evidence for a novel tick-borne disease complex. Arch Neurol, 58:1357-1363 <a href="https://pubmed.ncbi.nlm.nih.gov/11559306/" target="_blank" class="tab_link">PMID: 11559306</a> </li> </ul> <ul id="abstract" class="tab-articles long-article text-normal pub_list"> <li class="tab-container inline-block" data-company="19" data-year="2020" data-type="Meeting Abstracts"> Tarpinian S, Rowe J, Husanov R, Saha U, Banerjee P, Eraslan R, Jones B, Festin S, Khazak V. 2020. Invivotek, Hamilton, NJ. NexusPharma, Philadelphia, PA. Charles River Laboratories Research Models and Services (RMS), Wilmington, MA. Assessment of sensitivity to a PD-1 check point inhibitor and cisplatin in bladder cancer patient-derived xenografts with various levels of PD-L1 expression in HuCD34NCG mice. Society for Immunotherapy of Cancer 35th Anniversary Annual Meeting & Pre-Conference Programs (SITC 2020); November 9-14, 2020; Virtual. </li><li class="tab-container inline-block" data-company="19" data-year="2019" data-type="Meeting Abstracts"> Krais J, Clausen E, Khazak V, Astsaturov I, Scott CL, Johnson N. 2019. Assessment of PARPi and cisplatin resistance in BRCA1 exon 11 mutant patient-derived xenografts. American Association for Cancer Research (AACR) Special Conference on Advances in Ovarian Cancer Research; September 13-16, 2019; Atlanta, GA. </li><li class="tab-container inline-block" data-company="13" data-year="2015" data-type="Meeting Abstracts"> Stroke, IL, Ma, L, Letourneau, JJ, Cole, AG, Li, Y, Marinelli, BA, Malone, J, Paulish-Miller, T, Pechik, I, Quintero, JG, Sabalski, JE, Savoly, DR, Wang, A, Hilbert, DW, Gygax, S, Miller, DK, Stein, P, Webb, M. 2015. Miniaturized assays for RhoA inactivation through glucosylation by Clostridium difficile toxin. Society for Laboratory Automation and Screening 4th Annual Conference and Exhibition (Washington, D.C.) 7-11 February, 2015 </li><li class="tab-container inline-block" data-company="13" data-year="2013" data-type="Meeting Abstracts"> Beasley, JR, Huang, C-Y, Gallo-Ebert, C, Bata, A, Donigan, M, Giordano, C, Kanneganti, N, Malone, J, Sieber-McMaster, E, Nawoschik, S, O'Brien, L, Pham, Q, Severinova, E, Shi, D, Swanson, R, Tovar, K, Xu, X, Zalamea, P, Nickels, J, Stein, P., Webb, MW. 2013. Discovery and Optimization of GPBAR1 (TGR5) Agonists. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January 2013 </li><li class="tab-container inline-block" data-company="13" data-year="2013" data-type="Meeting Abstracts"> Uveges, A, Severinova, E, Gallagher, D, Kanneganti, N, McQueney, M, Swanson, R . 2013. A Robust Ultra-High-Throughput Screening Assay for DEK Binding to DNA. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013 </li><li class="tab-container inline-block" data-company="13" data-year="2013" data-type="Meeting Abstracts"> Stroke, IL, Sturzenbecker, LJ, Letourneau, JJ, Quintero, JG, Sabalski, Joan E, Marinelli, B, Pechik, I, Diller, D, Paulish-Miller, T, Hilbert, DW., Gygax, S, Stein, P, Webb, M. 2013. High throughput screening of combinatorial libraries for inhibitors of Clostridium difficile toxins. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013 </li><li class="tab-container inline-block" data-company="13" data-year="2013" data-type="Meeting Abstracts"> Stein, P. 2013. Simple and Complex Science and Technology. Rutgers University, November 21, 2013 </li><li class="tab-container inline-block" data-company="13" data-year="2012" data-type="Meeting Abstracts"> McQueney, MS, Uveges, A, Malone, J, O’Brien, L, Cole, A, Webb, M. 2012. An Ultra High Throughput Screen of the Venenum Discovery Library for PARP-1 Inhibitors for The 17th International Inflammation Research Association Conference (Lake George, New York) 9-13 September, 2012 </li><li class="tab-container inline-block" data-company="13" data-year="2012" data-type="Meeting Abstracts"> Stroke, IL, Hilbert, DW, Letourneau, JJ, Paulish-Miller, T, Quintero, JG, Sabalski, JE. 2012. Identification and Characterization of Small Molecules Targeting Clostridium difficile. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012 </li><li class="tab-container inline-block" data-company="13" data-year="2012" data-type="Meeting Abstracts"> Beasley, JR, Malone, J, O’Brien, L, Huang, C, Sieber-McMaster, E, Shi, D, Xu, X, Nawoschik, S, Pham, Q, Webb, M. 2012. Discovery of GPBAR1 (TGR5) Agonists from a 1536-well UHTS of the ECLiPS Compound Collection. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012 </li><li class="tab-container inline-block" data-company="13" data-year="2012" data-type="Meeting Abstracts"> Stroke IL, Hilbert DW, Letourneau JJ, Paulish-Miller T, Quintero JG, Sabalski JE. 2012. Identification and Characterization of Small Molecules Targeting Clostridium difficile. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012 </li><li class="tab-container inline-block" data-company="13" data-year="2012" data-type="Meeting Abstracts"> Webb, M. 2012. How to Mine Novel Biology Space with Technology Picks and Shovels. Kean University, March 12, 2012 </li><li class="tab-container inline-block" data-company="13" data-year="2012" data-type="Meeting Abstracts"> Webb, M. 2012. The Pivitol Role of Vertical Integration in Biotechnology. Rutgers University, November 5, 2012 </li><li class="tab-container inline-block" data-company="13" data-year="2011" data-type="Meeting Abstracts"> Huang C, Zhao J, Simhadri S, Webb M, Ohlmeyer M, Zhi L. 2011. Discovery of a Novel Series of mGluR5 Antagonists. Gordon Research Conference, Medicinal Chemistry, Colby- Sawyer College, New London, NH, August 7-12, 2011 </li><li class="tab-container inline-block" data-company="13" data-year="2011" data-type="Meeting Abstracts"> Swanson, RN, Stroke, IL, Manners, MT, Gallo-Ebert, C, Nickels, J. 2011. Engineering Transcription Factors for Use in Ultra-High Throughput DNA Binding Assays. 7th Annual Protein Engineering Summit (Boston, Massachusetts) 9-13 May, 2011 </li><li class="tab-container inline-block" data-company="13" data-year="2011" data-type="Meeting Abstracts"> Stroke, IL, Manners, MT, Swanson, RN, Dimitrov, D, Gallo-Ebert, C, Nickels, J. 2011. Targeting the Transcription Factor Upc2 for Antifungal Drug Discovery. Society for Biomolecular Sciences Annual Meeting (Orlando, Florida) 16-31 March, 2011 </li> </ul> </div> </main> <div class="main_button-container"> <a href="https://www.genesisglobalgrp.com/careers/" class="content-aboutus-button"> Careers </a> </div> <footer class="footer"> <svg height="0"> <clipPath id="footer-brown-topsvg" clipPathUnits="objectBoundingBox"> <path d="M0,1 L0,0.009 C0,0.009,0.2,0.909,0.5,0.909 C0.8,0.909,1,0.009,1,0.009 L1,1 L0,1"/> </clipPath> </svg> <div class="footer_top-container"> <div class="footer_logo-effects"> <svg class="footer_logo-radials" viewBox="0 0 1504 149" version="1.1" id="svg73"> <path fill-rule="evenodd" opacity="0.4" fill="rgb(250, 250, 250)" d="M1412.698,30.247 C1251.961,79.742 1087.290,118.432 919.941,137.341 C881.287,141.550 842.243,144.534 803.251,146.18 C808.953,145.422 814.647,144.752 820.330,144.20 C865.529,138.141 910.377,128.127 954.355,116.343 C1064.399,86.375 1171.528,46.215 1275.660,0.4 C1171.398,45.840 1064.153,85.621 954.46,115.195 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