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Saturday, November 23, 2024</div></section><div id="section-2" class="main-body"> <script src="/javascripts/pages/article.js"></script> <div id="breadcrumbs" class="breadcrumbs"><a class="" href="/">Home</a> » <a class="" href="/topics">Topics</a> » Conferences</div> <div class="box1 article-topic"> <div class="records"> <h1 class="page-title"> Conferences <div class="rss"> <a href="/rss/topic/154-conferences"> <img alt="Conferences RSS Feed" height="16" width="16" loading="lazy" src="/images/icons/rss.gif" /> RSS </a> </div> </h1> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Cancer</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714739-gsc-002639-shows-antitumor-efficacy-against-empik3ca-em-mutant-tumors">GSC-002639 shows antitumor efficacy against <em>PIK3CA</em>-mutant tumors</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 22, 2024</div> <div class="comment-count article-summary__comment-count"><a title="GSC-002639 shows antitumor efficacy against <em>PIK3CA</em>-mutant tumors" class="more" href="https://www.bioworld.com/articles/714739-gsc-002639-shows-antitumor-efficacy-against-empik3ca-em-mutant-tumors#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Mutations in the <em>PIK3CA</em> gene are present in about 4% to 36% of cancers such as breast, ovarian, endometrial and colorectal cancer, among others.<br /></div><a title="GSC-002639 shows antitumor efficacy against <em>PIK3CA</em>-mutant tumors" class="more" href="https://www.bioworld.com/articles/714739-gsc-002639-shows-antitumor-efficacy-against-empik3ca-em-mutant-tumors">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Immuno-oncology</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714738-bb-203-a-potentially-best-in-class-anti-pd-l1-anti-vegf-vhh-bispecific-antibody">BB-203, a potentially best-in-class anti-PD-L1/anti-VEGF VHH bispecific antibody</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 22, 2024</div> <div class="comment-count article-summary__comment-count"><a title="BB-203, a potentially best-in-class anti-PD-L1/anti-VEGF VHH bispecific antibody" class="more" href="https://www.bioworld.com/articles/714738-bb-203-a-potentially-best-in-class-anti-pd-l1-anti-vegf-vhh-bispecific-antibody#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Bright Biologics LLC reported the discovery and preclinical evaluation of BB-203, an anti-PD-L1/anti-VEGF bispecific antibody (Ab) being developed for the treatment of cancer.<br /></div><a title="BB-203, a potentially best-in-class anti-PD-L1/anti-VEGF VHH bispecific antibody" class="more" href="https://www.bioworld.com/articles/714738-bb-203-a-potentially-best-in-class-anti-pd-l1-anti-vegf-vhh-bispecific-antibody">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Endocrine/metabolic</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714736-hm-17321-a-crfr2-selective-ucn2-analogue-with-efficacy-in-models-of-obesity">HM-17321, a CRFR2-selective UCN2 analogue with efficacy in models of obesity</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 22, 2024</div> <div class="comment-count article-summary__comment-count"><a title="HM-17321, a CRFR2-selective UCN2 analogue with efficacy in models of obesity" class="more" href="https://www.bioworld.com/articles/714736-hm-17321-a-crfr2-selective-ucn2-analogue-with-efficacy-in-models-of-obesity#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Urocortin-2 (UCN2) is a selective corticotropin-releasing factor CRF2 receptor (CRFR2) agonist, which has been previously shown to reduce fat mass while promoting muscle hypertrophy. Hanmi Pharmaceutical Co. Ltd. presented the discovery and preclinical characterization of a novel CRFR2-selective UCN2 analogue, HM-17321, being developed for the treatment of obesity.<br /></div><a title="HM-17321, a CRFR2-selective UCN2 analogue with efficacy in models of obesity" class="more" href="https://www.bioworld.com/articles/714736-hm-17321-a-crfr2-selective-ucn2-analogue-with-efficacy-in-models-of-obesity">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Infection</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714727-edp-514-demonstrates-favorable-preclinical-pk-profile-excellent-target-tissue-penetration">EDP-514 demonstrates favorable preclinical PK profile, excellent target tissue penetration</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 22, 2024</div> <div class="comment-count article-summary__comment-count"><a title="EDP-514 demonstrates favorable preclinical PK profile, excellent target tissue penetration" class="more" href="https://www.bioworld.com/articles/714727-edp-514-demonstrates-favorable-preclinical-pk-profile-excellent-target-tissue-penetration#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Enanta Pharmaceuticals Inc. has released preclinical pharmacokinetics (PK) data for EDP-514, a potent and selective class II core assembly modulator in phase I development for the oral treatment of hepatitis B.<br /></div><a title="EDP-514 demonstrates favorable preclinical PK profile, excellent target tissue penetration" class="more" href="https://www.bioworld.com/articles/714727-edp-514-demonstrates-favorable-preclinical-pk-profile-excellent-target-tissue-penetration">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="ETX-258 improves cardiac function and structural remodeling post-MI" class="url" rel="" target="" href="https://www.bioworld.com/articles/714706-etx-258-improves-cardiac-function-and-structural-remodeling-post-mi"><img width="650" height="488" alt="Human heart within crosshairs" title="Human heart within crosshairs" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cardiovascular/heart-failure-attack-target.jpg?height=488&t=1715782430&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Cardiovascular</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714706-etx-258-improves-cardiac-function-and-structural-remodeling-post-mi">ETX-258 improves cardiac function and structural remodeling post-MI</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 21, 2024</div> <div class="comment-count article-summary__comment-count"><a title="ETX-258 improves cardiac function and structural remodeling post-MI" class="more" href="https://www.bioworld.com/articles/714706-etx-258-improves-cardiac-function-and-structural-remodeling-post-mi#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">At the American Heart Association’s Scientific Sessions, E-Therapeutics plc presented preclinical data for ETX-258, a Galomic siRNA being developed for the treatment of heart failure.<br /></div><a title="ETX-258 improves cardiac function and structural remodeling post-MI" class="more" href="https://www.bioworld.com/articles/714706-etx-258-improves-cardiac-function-and-structural-remodeling-post-mi">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="HOXB13 gene involved in metastatic omentum carcinoma, study shows" class="url" rel="" target="" href="https://www.bioworld.com/articles/714712-hoxb13-gene-involved-in-metastatic-omentum-carcinoma-study-shows"><img width="650" height="488" alt="DNA mutations or genetic disorder concept art" title="DNA mutations or genetic disorder concept art" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-library/DNA-gene-damage-mutation.jpg?height=488&t=1711552096&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Biomarkers</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714712-hoxb13-gene-involved-in-metastatic-omentum-carcinoma-study-shows">HOXB13 gene involved in metastatic omentum carcinoma, study shows</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 21, 2024</div> <div class="comment-count article-summary__comment-count"><a title="HOXB13 gene involved in metastatic omentum carcinoma, study shows" class="more" href="https://www.bioworld.com/articles/714712-hoxb13-gene-involved-in-metastatic-omentum-carcinoma-study-shows#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Primary tumors arising in the gastrointestinal system, ovary or pancreas may spread and lead to secondary cancers such as metastatic omentum cancer.<br /></div><a title="HOXB13 gene involved in metastatic omentum carcinoma, study shows" class="more" href="https://www.bioworld.com/articles/714712-hoxb13-gene-involved-in-metastatic-omentum-carcinoma-study-shows">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Cardiovascular</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714697-linoleic-acid-metabolite-reduces-atrial-arrhythmia-by-normalizing-camkii-levels">Linoleic acid metabolite reduces atrial arrhythmia by normalizing CaMKII levels</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 21, 2024</div> <div class="comment-count article-summary__comment-count"><a title="Linoleic acid metabolite reduces atrial arrhythmia by normalizing CaMKII levels" class="more" href="https://www.bioworld.com/articles/714697-linoleic-acid-metabolite-reduces-atrial-arrhythmia-by-normalizing-camkii-levels#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Researchers from Ohio State University hypothesized that 12,13-diHOME may act by inhibiting the proarrhythmic molecule Ca2+/calmodulin-dependent kinase II (CaMKII).<br /></div><a title="Linoleic acid metabolite reduces atrial arrhythmia by normalizing CaMKII levels" class="more" href="https://www.bioworld.com/articles/714697-linoleic-acid-metabolite-reduces-atrial-arrhythmia-by-normalizing-camkii-levels">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Gilead’s GS-6791 ameliorates arthritis symptoms in mice" class="url" rel="" target="" href="https://www.bioworld.com/articles/714696-gileads-gs-6791-ameliorates-arthritis-symptoms-in-mice"><img width="650" height="488" alt="Joint pain " title="Joint pain " border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Inflammatory/Joint-pain2.png?height=488&t=1642802876&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Musculoskeletal</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714696-gileads-gs-6791-ameliorates-arthritis-symptoms-in-mice">Gilead’s GS-6791 ameliorates arthritis symptoms in mice</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 21, 2024</div> <div class="comment-count article-summary__comment-count"><a title="Gilead’s GS-6791 ameliorates arthritis symptoms in mice" class="more" href="https://www.bioworld.com/articles/714696-gileads-gs-6791-ameliorates-arthritis-symptoms-in-mice#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Interleukin-1 receptor-associated kinase 4 is critical in the modulation of inflammatory responses through Toll-like receptor and IL-1R signaling.<br /></div><a title="Gilead’s GS-6791 ameliorates arthritis symptoms in mice" class="more" href="https://www.bioworld.com/articles/714696-gileads-gs-6791-ameliorates-arthritis-symptoms-in-mice">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Gastrointestinal</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714695-new-preclinical-data-on-cvi-2742-for-treating-mash">New preclinical data on CVI-2742 for treating MASH</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 21, 2024</div> <div class="comment-count article-summary__comment-count"><a title="New preclinical data on CVI-2742 for treating MASH" class="more" href="https://www.bioworld.com/articles/714695-new-preclinical-data-on-cvi-2742-for-treating-mash#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">The efficacy and capabilities of CVI Pharmaceuticals Inc.'s CVI-2742, a THR-β agonist, were tested in nonhuman primates.<br /></div><a title="New preclinical data on CVI-2742 for treating MASH" class="more" href="https://www.bioworld.com/articles/714695-new-preclinical-data-on-cvi-2742-for-treating-mash">Read More</a> </div> </article> <article class="record article-summary "> <div class="article-summary__details "> <div class="kicker article-summary__kicker">Gastrointestinal</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714684-rtx-001-an-engineered-macrophage-therapy-with-hepatic-regenerative-effects">RTX-001, an engineered macrophage therapy with hepatic regenerative effects </a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 21, 2024</div> <div class="comment-count article-summary__comment-count"><a title="RTX-001, an engineered macrophage therapy with hepatic regenerative effects " class="more" href="https://www.bioworld.com/articles/714684-rtx-001-an-engineered-macrophage-therapy-with-hepatic-regenerative-effects#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">As a consequence of chronic liver disease progression, severe cirrhosis, decompensation and fibrosis culminates in end-stage liver disease (ESLD). There are no treatment options approved for ESLD, but, among others, regenerative therapies with autologous, nonengineered, pro-regenerative macrophages have shown good tolerability and improved transplant-free survival in the clinical setting.<br /></div><a title="RTX-001, an engineered macrophage therapy with hepatic regenerative effects " class="more" href="https://www.bioworld.com/articles/714684-rtx-001-an-engineered-macrophage-therapy-with-hepatic-regenerative-effects">Read More</a> </div> </article> </div> <div class="pager"> <div role="navigation" aria-label="Pagination" class="pagination"><span class="previous_page disabled" aria-disabled="true">Previous</span> <em class="current" aria-label="Page 1" aria-current="page">1</em> <a rel="next" aria-label="Page 2" href="/articles/topic/154-conferences?page=2">2</a> <a aria-label="Page 3" href="/articles/topic/154-conferences?page=3">3</a> <a aria-label="Page 4" href="/articles/topic/154-conferences?page=4">4</a> <a aria-label="Page 5" href="/articles/topic/154-conferences?page=5">5</a> <a aria-label="Page 6" href="/articles/topic/154-conferences?page=6">6</a> <a aria-label="Page 7" href="/articles/topic/154-conferences?page=7">7</a> <a aria-label="Page 8" href="/articles/topic/154-conferences?page=8">8</a> <a aria-label="Page 9" href="/articles/topic/154-conferences?page=9">9</a> <span class="gap">…</span> <a aria-label="Page 3102" href="/articles/topic/154-conferences?page=3102">3102</a> <a aria-label="Page 3103" href="/articles/topic/154-conferences?page=3103">3103</a> <a class="next_page" rel="next" href="/articles/topic/154-conferences?page=2">Next</a></div> </div> </div> </div><aside class="main-interior-sidebar"><div class="main-interior-sidebar__column"><div id="article-recommendations"></div> </div><div class="main-interior-sidebar__column"><section class="popular-stories "> <h1 class="popular-stories__title">Popular Stories</h1><ul class="popular-stories__items"> <li class="popular-stories__item"> <article class="popular-stories__article popular-stories--article"><div class="popular-stories__details popular-stories__details-1"><h1 class="popular-stories__headline"><a class="popular-stories__article-title-link" href="https://www.bioworld.com/articles/432891-todays-news-in-brief">Today's news in brief</a></h1><div class="popular-stories__topics"><a class="popular-stories__topic-link" href="/topics/84-bioworld">BioWorld</a></div><div class="popular-stories__teaser"><em>BioWorld</em> briefs for Nov. 22, 2024.</div></div></article> </li> <li class="popular-stories__item"> <article class="popular-stories__article popular-stories--article"><div class="popular-stories__details popular-stories__details-1"><h1 class="popular-stories__headline"><a class="popular-stories__article-title-link" href="https://www.bioworld.com/articles/699574-todays-news-in-brief">Today's news in brief</a></h1><div class="popular-stories__topics"><a class="popular-stories__topic-link" href="/topics/85-bioworld-medtech">BioWorld MedTech</a></div><div class="popular-stories__teaser"><em>BioWorld MedTech</em> briefs for November 21, 2024.</div></div></article> </li> <li class="popular-stories__item"> <article class="popular-stories__article -has-image popular-stories--article"><figure class="popular-stories__image"><a class="popular-stories__thumbnail-link" data-eventname="popular-stories" data-eventcategory="click" data-eventaction="popular-stories-image" data-eventlabel="https://www.bioworld.com/articles/714048-j-and-js-ottava-robotic-system-approved-for-us-pivotal-trial" href="https://www.bioworld.com/articles/714048-j-and-js-ottava-robotic-system-approved-for-us-pivotal-trial"><img class="popular-stories__image-thumb" alt="Da Vinci Xi robot - Intuitive Surgical" title="Da Vinci Xi robot - Intuitive Surgical" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/BMT-source/2023/1-26--Da-Vinci-Xi-robot-Intuitive-Surgical.png?height=355&t=1699482891&width=640" /></a></figure><div class="popular-stories__details popular-stories__details-1"><h1 class="popular-stories__headline"><a class="popular-stories__article-title-link" href="https://www.bioworld.com/articles/714048-j-and-js-ottava-robotic-system-approved-for-us-pivotal-trial">J&J’s Ottava robotic system approved for US pivotal trial</a></h1><div class="popular-stories__topics"><a class="popular-stories__topic-link" href="/topics/85-bioworld-medtech">BioWorld MedTech</a></div><div class="popular-stories__teaser">Johnson & Johnson received U.S. FDA investigational device exemption to begin the pivotal clinical trial for the Ottava robotic surgical system. 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