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.gt-menu > li:hover > a, .gt-sticky-header .gt-navbar .gt-menu > li:hover > a:visited .gt-sticky-header .gt-navbar .gt-menu > li:focus > a, .gt-sticky-header .gt-navbar .gt-menu > li:focus > a:visited{color:#6600ff;}.gt-header.gt-style-1 .gt-elements .gt-user-box, .gt-header.gt-style-3 .gt-elements .gt-user-box, .gt-header.gt-style-5 .gt-elements .gt-user-box, .gt-sticky-header .gt-elements .gt-user-box, .gt-countdown-slider.gt-style-1 > .gt-counter:before{background:#6600ff;}.gt-header.gt-style-1 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-3 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-5 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-sticky-header .gt-navbar .gt-menu li .gt-dropdown-menu{border-top-color:#6600ff;}.gt-footer.gt-style-1{background-image: url(http://www.uventia.com/wp-content/uploads/2020/11/Futer-1-scaled.jpg);}.gt-footer.gt-style-2{background-image: 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.gt-list ul li a:focus, .gt-event-schedule.gt-style-4 > .gt-item > ul > li .gt-content .gt-schedule-speakers .gt-list ul a:hover, .gt-event-schedule.gt-style-4 > .gt-item > ul > li .gt-content .gt-schedule-speakers .gt-list ul li a:focus, .gt-event-schedule.gt-style-5 > .gt-item > ul > li .gt-content .gt-schedule-speakers .gt-list ul a:hover, .gt-event-schedule.gt-style-5 > .gt-item > ul > li .gt-content .gt-schedule-speakers .gt-list ul li a:focus, .gt-event-schedule.gt-style-6 > .gt-item > ul > li .gt-content .gt-schedule-speakers .gt-list ul a:hover, .gt-event-schedule.gt-style-6 > .gt-item > ul > li .gt-content .gt-schedule-speakers .gt-list ul li a:focus, .gt-organizers.gt-style-1 ul li a:hover, .gt-organizers.gt-style-1 ul li a:focus, .gt-organizers.gt-style-2 ul li a:hover, .gt-organizers.gt-style-2 ul li a:focus, .gt-tags.gt-style-1 ul li a:hover, .gt-tags.gt-style-1 ul li a:focus, .gt-tags.gt-style-2 ul li a:hover, .gt-tags.gt-style-2 ul li a:focus, .gt-categories.gt-style-1 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content="WordPress 6.7.1" /> <link rel='shortlink' href='https://www.uventia.com/?p=5684' /> <link rel="alternate" title="oEmbed (JSON)" type="application/json+oembed" href="https://www.uventia.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.uventia.com%2Fevent%2F3rd-annual-genotoxic-impurities-summit-nitrosamines-beyond-2023%2F" /> <link rel="alternate" title="oEmbed (XML)" type="text/xml+oembed" href="https://www.uventia.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.uventia.com%2Fevent%2F3rd-annual-genotoxic-impurities-summit-nitrosamines-beyond-2023%2F&format=xml" /> <script>var cf7windowWidth = 500;var cf7simplePopupAutoClose = 4000;</script> <link rel="preconnect" href="https://fonts.googleapis.com"> <link rel="preconnect" href="https://fonts.gstatic.com">  <script type="application/ld+json">{"@context": "https://schema.org","@type": "Event","name": "3rd Annual Genotoxic Impurities Summit: Nitrosamines & Beyond 2023","description": "Learn the best techniques and cutting-edge methods for reducing genotoxic and elemental impurities. Recording of 2 days event sessions [17 video sessions].","about": "[vc_row][vc_column width="2/3"][vc_single_image image="8293" img_size="full" alignment="center" style="vc_box_rounded"][/vc_column][vc_column width="1/3" offset="vc_col-lg-offset-0" css=".vc_custom_1605300510210{margin-top: 2px !important;margin-bottom: 2px !important;}"][vc_empty_space height="75px"][eventchamp_modal_button style="2" align="center" inline="false" margin="false" buttontitle="REQUEST BROCHURE" icon="" svg-icon="" text="" shortcode="" iframe=""][contact-form-7 id="2928" title="request brochure form"][/eventchamp_modal_button][vc_empty_space height="25px"][eventchamp_button style="2" align="center" inline="false" margin="false" buttonlink="url:https%3A%2F%2Fwww.uventia.com%2Fregister-now-for-3rd-annual-genotoxic-impurities-summit-nitrosamines-beyond-2023|title:BUY%20RECORDINGS" icon="" svg-icon="JTNDaSUyMGNsYXNzJTNEJTIyZmEtc29saWQlMjBmYS12aWRlbyUyMiUzRSUzQyUyRmklM0U="][/vc_column][/vc_row][vc_row disable_element="yes"][vc_column][vc_column_text] CONFERENCE OVERVIEW The safety, quality and clinical results of drug substances and drug products may be disrupted by the formation of nitrosamines along with other mutagenic impurities. The comprehensive development and production of innovative medicines now inevitably involves estimating impurity profiles as well as managing and monitoring them. To meet the demands of ever-increasing regulatory standards and avoid expensive recalls, proactive detection of genotoxic contaminants should be adopted at every stage of pharmaceutical development. We plan an online meeting with subject-matter experts to evaluate multiple perspectives on how to handle the concerns of mutagenic impurities. We will cover regulatory-compliant drug impurity profiling practices; helpful hints for adhering to recent ICH M7 and Q3D updates; nitrosamine impurity identification and quantification; risk evaluation of genotoxic impurities; analytical challenges and genotoxicity prediction; establishment of acceptance criteria; and the most recent developments in the analysis of elemental impurities. Save a seat at our webinar to find out about most effective methods for genotoxic and other mutagenic impurity management.[/vc_column_text][/vc_column][vc_column][vc_column_text] WE WILL TALK ABOUT Revisiting the landscape of complex nitrosamines. The EDQM response to nitrosamines. Management of N-nitrosamines and their risk assessment within GSK R&D. Setting limits for NDSRIs. Using genetic toxicity data to support risk assessment of nitrosamines. Nitrosamines, industry perspective. Setting acceptable intakes (AIS) for complex nitrosamines. Toxicological assessment of nitrosamines. Nitrosamine drug substance - related impurities management at SEQENS. In silico evaluations to assess mutagenicity of impurities. ICH M7 approaches in peptides that are developed as NCEs. Genotoxic impurities in medical devices. Extractables and leachables - potential genotoxic impurities? Expert analysis and in-silico QSAR methodologies to assess the mutagenicity potential of impurities. Toxicological risk assessment, ISO certification, compliance, art and sciences of chemical characterization of nitrosamines. Are we doing the right thing? An update on the ongoing efforts to optimize the ames assay by the hesigttc mechanism-based genotoxicity risk assessment (MGRA) nitrosamine subgroup. Challenges encountered during the attempted quantification of nitrosodimethylamine (NDMA) in rubber using traditional extraction techniques. [/vc_column_text][/vc_column][vc_column][vc_column_text] WHO IS IT FOR? CxO, VPs, Directors, Heads, Managers of Genotoxic Impurities/ GTIs/ Genotoxins/ Elemental Impurities Genotoxicity/ Mutagenicity Carcinogenicity/ Carcinogens Genetic Toxicology/ Chemical Toxicology/ Computational Toxicology Analytical Chemistry/ Analytical Development/ Analytical Science Drug Discovery/ Drug Development/ Drug Substance Drug Safety/ Compound Safety Process Chemistry/ Process Development Product Characterisation/ Risk Assessment Pharmacokinetics/ Metabolism Extractables & Leachables API Development/ Degradation Products LC-MS/ Mass Spectrometry Good Laboratory Practice (GLP)/ Good Manufacturing Practice (GMP) Regulatory Affairs & Compliance [/vc_column_text][vc_empty_space][/vc_column][/vc_row][vc_row disable_element="yes"][vc_column width="1/4"][vc_single_image image="8294" img_size="medium" alignment="center"][/vc_column][vc_column width="3/4"][vc_column_text] [Agenda] 3rd Annual Genotoxic Impurities Summit: Nitrosamines & Beyond 2023 Download the full summit program to 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include-tags=""][/vc_column][vc_column][vc_empty_space][/vc_column][/vc_row][vc_row disable_element="yes"][vc_column][vc_tta_tabs style="modern" active_section="1"][vc_tta_section i_type="openiconic" i_icon_openiconic="vc-oi vc-oi-calendar" add_icon="true" title="ATTENDEES IN 2023" tab_id="3-gti-6"][vc_column_text]● A&M STABTEST GmbH ● Abbott ● ACG Europe d.o.o. ● Adamed Pharma S.A. ● Advanz Pharma ● AGES-MEA ● ALK-Abelló S.A. ● American Regent ● AMSlab ● Angelini Pharma S.p.A. ● APIs & NCE Manufacturing LeadAC Immune SA ● Aptuit an Evotec Company ● ARLANXEO Netherlands B.V ● Arrotex Pharmaceuticals Pty Ltd ● Astellas Pharma Europe BV ● Astellas Pharma Inc. ● AstraZeneca ● BD Technologies ● Boehringer Ingelheim Pharma GmbH & Co. KG ● Charles River Laboratories ● Chugai Pharmaceutical Co., Ltd. ● Croma-Pharma GmbH ● CSL Behring ● Dottikon Exclusive Synthesis AG ● EDQM, Council of Europe ● Excella GmbH & Co. KG ● FARMAK, a.s. ● Fermion Oy ● Fresenius Kabi ● Fresenius Kabi Deutschland GmbH ● FUJIFILM Toyama Chemical ● Gentronix Ltd ● Grunenthal Ecuatoriana Cia. Ltda. ● GSK ● Haleon ● Health and Environmental Sciences Institute (HESI) ● Hemofarm AD ● Hemomont d.o.o. ● Idorsia ● Insight Exposure and Risk Sciences ● Intertek ● Intertek Melbourn ● Intox Private Limited ● Intuitive Fluorescence Imaging, LLC ● Johnson&Johnson ● Konya Food and Agriculture University ● Krka d. d., Novo mesto ● L.Molteni & C. dei F.lli Alitti SpA ● LabAnalysis S.r.l. ● Laboratoires MAYOLY SPINDLER ● Labtim ADRIA d.o.o. ● LangAllan CMC Regulatory Solutions Ltd ● Lek Pharmaceuticals d.d. ● Lhasa Limited ● Lundbeck ● Luye Pharma AG ● Merck Healthcare KGaA ● Midas Pharma GmbH ● MultiCASE Inc ● National Institute of Health Sciences ● Norwich Pharmaceuticals ● Novartis ● Olon S.p.A. ● Orion Pharma ● Pfizer ● Pharmaceutical firm Darnitsa ● Polpharma ● Preclintox Services, LLC ● ProBioGen AG ● Rontis Hellas ● S-IN Soluzioni Informatiche ● Safetree Consulting e.U. ● Sanofi ● SEQENS ● Solvias AG ● State Agency of Medicines ● Swansea University ● Swissmedic ● Takeda ● Takeda Pharmaceuticals ● Tallinn University of Technology ● Teva Pharmaceutical Industries Ltd. ● TEVA Pharmaceutical Works Ltd ● Teva Pharmaceuticals ● ToxMinds BVBA ● UCB ● Vertex Pharmaceuticals ● Viatris ● Waters ● Waters Corporation ● Zakłady Farmaceutyczne Polpharma ● Zentiva Group, a.s.[/vc_column_text][/vc_tta_section][vc_tta_section i_type="openiconic" i_icon_openiconic="vc-oi vc-oi-calendar" add_icon="true" title="ATTENDEES IN 2022" tab_id="3-gti-4"][vc_column_text] ● Adamed Pharma ● Lundbeck ● Astellas Pharma Europe B.V. ● Sanofi ● Dr. Reddy's Laboratories Limited ● Airnov Healthcare Packaging ● Egis Pharmaceuticals Plc. ● Waters Corporation ● Teva Pharmaceutical ● Synthon ● Synthon B.V. ● Polpharma ● Silence Therapeutics ● Menarini Ricerche ● Polpharma SA ● Krka ● Teva Pharmaceutical Industries Ltd ● Teva Active Pharmaceutical Ingredients ● Neurocrine Biosciences ● JSC Olainfarm ● Bibra toxicology advice & consulting Ltd ● Berlin-Chemie AG ● Janssen Pharmaceutica ● Jazz Pharmaceuticals ● Pliva Hrvatska d.o.o. ● Dr. Anika Schroeter e.U. ● Eurofins PSS ● Angelini Pharma S.p.A. ● Food and Drug Administration ● Astellas Pharma Europe ● Saneca Pharmaceuticals ● Teva Israel Ltd ● Arrotex Pty Ltd ● Merck Healthcare KGaA ● Boehringer Ingelheim Pharma GmbH & Co. KG ● Bracco Imaging SpA ● Perrigo ● Chiesi Farmaceutici SpA ● Advanz Pharma ● Midas Pharma GmbH ● Aptuit an Evotec Company ● Hikma Pharmaceuticals ● Aptuit (Verona) S.r.L., An Evotec Company ● Adamed Pharma S.A. ● fagg-afmps ● World Health Organization (WHO) ● Curia Spain S.A.U. ● Swissmedic ● Albhades ● Finnish Medicines Agency ● Selvita S.A. ● Fresenius Medical Care Deutschland GmbH ● Fresenius Kabi ● IFF ● Teva Ni Ltd ● Bayer AG ● FUJIFILM Toyama Chemical Co., Ltd. ● INEOS Oxide ● Affygility Solutions ● Laboratorium Zdrochem sp. z o.o. ● Zentiva, k.s. ● Janssen ● Bachem AG ● BD ● Jagiellonian Center of Innovation ● Sanofi Chimie ● Venn Life Sciences ● Merck KGaA, Darmstadt, Germany ● Teva Gyogyszergyar Zrt. ● Drug Development Solutions ● Senior Consultant ● Lonza AG ● Alliance Pharmaceuticals Ltd ● Minakem ● B. 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c0.023,0.008,0.045,0.017,0.068,0.025c0.345,0.118,0.685,0.253,1.022,0.406C54.347,37.729,57,41.557,57,46 C57,52.065,52.065,57,46,57z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Start Date</div><div class="gt-inner">November 30, 2023 9:30 am</div></div></li><li class="gt-end-date"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59 59" xml:space="preserve"> <g> <path d="M50.95,41.13c-0.391-0.391-1.023-0.391-1.414,0L46,44.666l-3.536-3.536c-0.391-0.391-1.023-0.391-1.414,0 s-0.391,1.023,0,1.414l3.536,3.536l-3.536,3.536c-0.391,0.391-0.391,1.023,0,1.414c0.195,0.195,0.451,0.293,0.707,0.293 s0.512-0.098,0.707-0.293L46,47.494l3.536,3.536c0.195,0.195,0.451,0.293,0.707,0.293s0.512-0.098,0.707-0.293 c0.391-0.391,0.391-1.023,0-1.414l-3.536-3.536l3.536-3.536C51.34,42.153,51.34,41.521,50.95,41.13z"/> <path d="M52,34.479V15V5c0-0.553-0.448-1-1-1h-5V1c0-0.553-0.448-1-1-1h-7c-0.552,0-1,0.447-1,1v3H15V1c0-0.553-0.448-1-1-1H7 C6.448,0,6,0.447,6,1v3H1C0.448,4,0,4.447,0,5v10v41c0,0.553,0.448,1,1,1h38.104c2.002,1.26,4.362,2,6.896,2 c7.168,0,13-5.832,13-13C59,40.997,56.154,36.651,52,34.479z M39,2h5v3v3h-5V5V2z M8,2h5v3v3H8V5V2z M2,6h4v3c0,0.553,0.448,1,1,1 h7c0.552,0,1-0.447,1-1V6h22v3c0,0.553,0.448,1,1,1h7c0.552,0,1-0.447,1-1V6h4v8H2V6z M2,55V16h48v17.636 c-0.196-0.063-0.396-0.114-0.596-0.169c-0.185-0.051-0.37-0.101-0.557-0.144c-0.169-0.038-0.34-0.071-0.511-0.102 c-0.244-0.045-0.489-0.082-0.735-0.113c-0.137-0.017-0.273-0.036-0.411-0.049C46.796,33.024,46.399,33,46,33 c-0.338,0-0.669,0.025-1,0.051V32v-2v-9h-9h-2h-7h-2h-7h-2H7v9v2v7v2v9h9h2h7h2h6.636c0.029,0.088,0.065,0.173,0.095,0.26 c0.084,0.243,0.167,0.487,0.266,0.724c0.055,0.133,0.12,0.26,0.18,0.39c0.115,0.254,0.232,0.507,0.363,0.753 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<g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">End Date</div><div class="gt-inner">December 1, 2023 5:20 pm</div></div></li><li class="gt-status"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 52 52" xml:space="preserve"> <g> <path d="M26,0C11.664,0,0,11.663,0,26s11.664,26,26,26s26-11.663,26-26S40.336,0,26,0z M26,50C12.767,50,2,39.233,2,26 S12.767,2,26,2s24,10.767,24,24S39.233,50,26,50z"/> <path d="M38.252,15.336l-15.369,17.29l-9.259-7.407c-0.43-0.345-1.061-0.274-1.405,0.156c-0.345,0.432-0.275,1.061,0.156,1.406 l10,8C22.559,34.928,22.78,35,23,35c0.276,0,0.551-0.114,0.748-0.336l16-18c0.367-0.412,0.33-1.045-0.083-1.411 C39.251,14.885,38.62,14.922,38.252,15.336z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Status</div><div class="gt-inner"><div class="gt-event-status">Expired</div></div></div></li><li class="gt-locations"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 54.757 54.757" xml:space="preserve"> <g> <path d="M27.557,12c-3.859,0-7,3.141-7,7s3.141,7,7,7s7-3.141,7-7S31.416,12,27.557,12z M27.557,24c-2.757,0-5-2.243-5-5 s2.243-5,5-5s5,2.243,5,5S30.314,24,27.557,24z"/> <path d="M40.94,5.617C37.318,1.995,32.502,0,27.38,0c-5.123,0-9.938,1.995-13.56,5.617c-6.703,6.702-7.536,19.312-1.804,26.952 L27.38,54.757L42.721,32.6C48.476,24.929,47.643,12.319,40.94,5.617z M41.099,31.431L27.38,51.243L13.639,31.4 C8.44,24.468,9.185,13.08,15.235,7.031C18.479,3.787,22.792,2,27.38,2s8.901,1.787,12.146,5.031 C45.576,13.08,46.321,24.468,41.099,31.431z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Location</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/location/online/?post_type=event">Online</a></li></ul></div></div></li><li class="gt-ticket-price"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59.997 59.997" style="enable-background:new 0 0 59.997 59.997;" xml:space="preserve"> <g> <path d="M19.519,21.05c-0.39,0.4-0.38,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.391,0.39-1.021,0-1.41C20.539,20.66,19.908,20.66,19.519,21.05z"/> <path d="M16.668,46.56c-0.39,0.391-0.39,1.03,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.29 c0.39-0.39,0.39-1.029,0-1.42C17.688,46.17,17.059,46.17,16.668,46.56z"/> <path d="M16.708,23.89c-0.39,0.391-0.39,1.03,0,1.42c0.2,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.72-0.3 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d="M8.178,38.08c-0.39,0.39-0.39,1.02,0,1.41c0.2,0.199,0.45,0.3,0.71,0.3c0.26,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.39-1.021,0-1.41C9.208,37.689,8.568,37.689,8.178,38.08z"/> <path d="M8.258,32.41c-0.39,0.399-0.39,1.029,0,1.42c0.2,0.189,0.45,0.29,0.71,0.29c0.25,0,0.51-0.101,0.7-0.301 c0.39-0.39,0.39-1.02,0-1.409C9.278,32.02,8.638,32.02,8.258,32.41z"/> <path d="M5.438,35.25c-0.39,0.399-0.39,1.03,0,1.42c0.2,0.189,0.45,0.29,0.71,0.29c0.25,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.38-1.021-0.01-1.41C6.458,34.859,5.828,34.859,5.438,35.25z"/> <path d="M25.158,15.37c-0.39,0.399-0.39,1.029,0,1.42c0.2,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.72-0.3 c0.38-0.391,0.38-1.021-0.01-1.41C26.178,14.979,25.539,14.979,25.158,15.37z"/> <path d="M11.008,40.91c-0.39,0.39-0.39,1.02,0,1.409c0.2,0.2,0.45,0.29,0.71,0.29c0.25,0,0.51-0.09,0.71-0.29 c0.39-0.39,0.39-1.02,0-1.409C12.028,40.52,11.398,40.52,11.008,40.91z"/> <path 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d="M41.868,35.09c-0.39,0.39-0.38,1.02,0.02,1.41c0.19,0.189,0.44,0.28,0.69,0.28c0.27,0,0.53-0.101,0.72-0.301 c0.39-0.399,0.38-1.029-0.02-1.41C42.888,34.68,42.249,34.689,41.868,35.09z"/> <path d="M47.448,29.35c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.7,0.28c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C48.468,28.95,47.828,28.96,47.448,29.35z"/> <circle cx="50.499" cy="19" r="1"/> <path d="M27.918,49.41c-0.39,0.399-0.38,1.029,0.02,1.42c0.19,0.189,0.44,0.279,0.69,0.279c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.399,0.38-1.029-0.02-1.41C28.928,49.01,28.298,49.02,27.918,49.41z"/> <circle cx="50.499" cy="27" r="1"/> <circle cx="50.499" cy="23" r="1"/> <path d="M33.499,43.68c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C34.508,43.28,33.878,43.29,33.499,43.68z"/> <path d="M39.918,9c0-0.55-0.45-1-1-1c-0.56,0-1,0.45-1,1s0.44,1,1,1C39.468,10,39.918,9.55,39.918,9z"/> <path d="M27.968,12.53c-0.39,0.39-0.38,1.029,0.01,1.42c0.19,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.301 c0.39-0.39,0.39-1.02,0-1.409C28.988,12.14,28.358,12.14,27.968,12.53z"/> <path d="M30.789,9.689c-0.39,0.4-0.39,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.3 c0.39-0.39,0.39-1.02-0.01-1.41C31.809,9.3,31.178,9.3,30.789,9.689z"/> <path d="M34.918,8c-0.56,0-1,0.45-1,1s0.44,1,1,1c0.55,0,1-0.45,1-1S35.468,8,34.918,8z"/> <path d="M36.289,40.819c-0.39,0.391-0.38,1.03,0.02,1.41c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.391,0.38-1.03-0.02-1.41C37.309,40.41,36.668,40.42,36.289,40.819z"/> <path d="M59.206,0.293c-0.391-0.391-1.023-0.391-1.414,0L54.084,4H30.802L1.532,33.511c-0.667,0.666-1.034,1.553-1.034,2.495 s0.367,1.829,1.034,2.495l20.466,20.466c0.687,0.687,1.588,1.03,2.491,1.03c0.906,0,1.814-0.346,2.508-1.04l28.501-29.271V5.414 l3.707-3.707C59.596,1.316,59.596,0.684,59.206,0.293z M53.499,28.874L25.574,57.553c-0.595,0.596-1.565,0.596-2.162,0 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<path d="M48.014,42.889l-9.553-4.776C37.56,37.662,37,36.756,37,35.748v-3.381c0.229-0.28,0.47-0.599,0.719-0.951 c1.239-1.75,2.232-3.698,2.954-5.799C42.084,24.97,43,23.575,43,22v-4c0-0.963-0.36-1.896-1-2.625v-5.319 c0.056-0.55,0.276-3.824-2.092-6.525C37.854,1.188,34.521,0,30,0s-7.854,1.188-9.908,3.53C17.724,6.231,17.944,9.506,18,10.056 v5.319c-0.64,0.729-1,1.662-1,2.625v4c0,1.217,0.553,2.352,1.497,3.109c0.916,3.627,2.833,6.36,3.503,7.237v3.309 c0,0.968-0.528,1.856-1.377,2.32l-8.921,4.866C8.801,44.424,7,47.458,7,50.762V54c0,4.746,15.045,6,23,6s23-1.254,23-6v-3.043 C53,47.519,51.089,44.427,48.014,42.889z M51,54c0,1.357-7.412,4-21,4S9,55.357,9,54v-3.238c0-2.571,1.402-4.934,3.659-6.164 l8.921-4.866C23.073,38.917,24,37.354,24,35.655v-4.019l-0.233-0.278c-0.024-0.029-2.475-2.994-3.41-7.065l-0.091-0.396l-0.341-0.22 C19.346,23.303,19,22.676,19,22v-4c0-0.561,0.238-1.084,0.67-1.475L20,16.228V10l-0.009-0.131c-0.003-0.027-0.343-2.799,1.605-5.021 C23.253,2.958,26.081,2,30,2c3.905,0,6.727,0.951,8.386,2.828c1.947,2.201,1.625,5.017,1.623,5.041L40,16.228l0.33,0.298 C40.762,16.916,41,17.439,41,18v4c0,0.873-0.572,1.637-1.422,1.899l-0.498,0.153l-0.16,0.495c-0.669,2.081-1.622,4.003-2.834,5.713 c-0.297,0.421-0.586,0.794-0.837,1.079L35,31.623v4.125c0,1.77,0.983,3.361,2.566,4.153l9.553,4.776 C49.513,45.874,51,48.28,51,50.957V54z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Organizer</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/event-organizer/uventia/?post_type=event">Uventia</a></li></ul></div></div></li><li class="gt-categories"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 60 60" xml:space="preserve"> <path d="M57.49,21.5H54v-6.268c0-1.507-1.226-2.732-2.732-2.732H26.515l-5-7H2.732C1.226,5.5,0,6.726,0,8.232v43.687l0.006,0 c-0.005,0.563,0.17,1.114,0.522,1.575C1.018,54.134,1.76,54.5,2.565,54.5h44.759c1.156,0,2.174-0.779,2.45-1.813L60,24.649v-0.177 C60,22.75,58.944,21.5,57.49,21.5z M2,8.232C2,7.828,2.329,7.5,2.732,7.5h17.753l5,7h25.782c0.404,0,0.732,0.328,0.732,0.732V21.5 H12.731c-0.144,0-0.287,0.012-0.426,0.036c-0.973,0.163-1.782,0.873-2.023,1.776L2,45.899V8.232z M47.869,52.083 c-0.066,0.245-0.291,0.417-0.545,0.417H2.565c-0.243,0-0.385-0.139-0.448-0.222c-0.063-0.082-0.16-0.256-0.123-0.408l10.191-27.953 c0.066-0.245,0.291-0.417,0.545-0.417H54h3.49c0.38,0,0.477,0.546,0.502,0.819L47.869,52.083z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Category</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/event-category/pharma/?post_type=event">Pharma</a></li></ul></div></div></li><li class="gt-email"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 512 512" xml:space="preserve"> <g> <g> <g> <path d="M486.4,59.733H25.6c-14.138,0-25.6,11.461-25.6,25.6v341.333c0,14.138,11.461,25.6,25.6,25.6h460.8 c14.138,0,25.6-11.461,25.6-25.6V85.333C512,71.195,500.539,59.733,486.4,59.733z M494.933,426.667 c0,4.713-3.82,8.533-8.533,8.533H25.6c-4.713,0-8.533-3.82-8.533-8.533V85.333c0-4.713,3.82-8.533,8.533-8.533h460.8 c4.713,0,8.533,3.82,8.533,8.533V426.667z"/> <path d="M470.076,93.898c-2.255-0.197-4.496,0.51-6.229,1.966L266.982,261.239c-6.349,5.337-15.616,5.337-21.965,0L48.154,95.863 c-2.335-1.96-5.539-2.526-8.404-1.484c-2.865,1.042-4.957,3.534-5.487,6.537s0.582,6.06,2.917,8.02l196.864,165.367 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aria-controls="gt-event-tab-2" aria-selected="true">SPEAKERS</a></li><li><a data-toggle="tab" href="#gt-event-tab-3" data-gt-type="content" role="tab" aria-controls="gt-event-tab-3" aria-selected="true">AGENDA</a></li></ul><div class="tab-content"><div class="tab-pane fade active show" id="gt-event-tab-1" data-gt-type="content" role="tabpanel" aria-labelledby="nav-gt-event-tab-1-tab"><div class="gt-content"><p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p style="text-align: left;padding-left: 40px"><strong>CONFERENCE <span class="has-inline-color has-luminous-vivid-amber-color"><span style="color: #ffbb00">OVERVIEW</span><br /> </span></strong></p> <p>The safety, quality and clinical results of drug substances and drug products may be disrupted by the formation of nitrosamines along with other mutagenic impurities. The comprehensive development and production of innovative medicines now inevitably involves estimating impurity profiles as well as managing and monitoring them. To meet the demands of ever-increasing regulatory standards and avoid expensive recalls, proactive detection of genotoxic contaminants should be adopted at every stage of pharmaceutical development.</p> <p>We plan an online meeting with subject-matter experts to evaluate multiple perspectives on how to handle the concerns of mutagenic impurities. We will cover regulatory-compliant drug impurity profiling practices; helpful hints for adhering to recent ICH M7 and Q3D updates; nitrosamine impurity identification and quantification; risk evaluation of genotoxic impurities; analytical challenges and genotoxicity prediction; establishment of acceptance criteria; and the most recent developments in the analysis of elemental impurities.</p> <p>Save a seat at our webinar to find out about most effective methods for genotoxic and other mutagenic impurity management.</p> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p style="text-align: left;padding-left: 40px"><strong>WE WILL <span style="color: #ffbb00">TALK ABOUT</span></strong></p> <ul> <li>Revisiting the landscape of complex nitrosamines.</li> <li>The EDQM response to nitrosamines.</li> <li>Management of N-nitrosamines and their risk assessment within GSK R&D.</li> <li>Setting limits for NDSRIs.</li> <li>Using genetic toxicity data to support risk assessment of nitrosamines.</li> <li>Nitrosamines, industry perspective.</li> <li>Setting acceptable intakes (AIS) for complex nitrosamines.</li> <li>Toxicological assessment of nitrosamines.</li> <li>Nitrosamine drug substance - related impurities management at SEQENS.</li> <li>In silico evaluations to assess mutagenicity of impurities.</li> <li>ICH M7 approaches in peptides that are developed as NCEs.</li> <li>Genotoxic impurities in medical devices.</li> <li>Extractables and leachables - potential genotoxic impurities?</li> <li>Expert analysis and in-silico QSAR methodologies to assess the mutagenicity potential of impurities.</li> <li>Toxicological risk assessment, ISO certification, compliance, art and sciences of chemical characterization of nitrosamines. Are we doing the right thing?</li> <li>An update on the ongoing efforts to optimize the ames assay by the hesigttc mechanism-based genotoxicity risk assessment (MGRA) nitrosamine subgroup.</li> <li>Challenges encountered during the attempted quantification of nitrosodimethylamine (NDMA) in rubber using traditional extraction techniques.</li> </ul> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p style="text-align: left;padding-left: 40px"><strong>WHO IS <span style="color: #ffbb00">IT FOR?</span></strong></p> <p><strong>CxO, VPs, Directors, Heads, Managers of</strong></p> <ul> <li>Genotoxic Impurities/ GTIs/ Genotoxins/ Elemental Impurities</li> <li>Genotoxicity/ Mutagenicity</li> <li>Carcinogenicity/ Carcinogens</li> <li>Genetic Toxicology/ Chemical Toxicology/ Computational Toxicology</li> <li>Analytical Chemistry/ Analytical Development/ Analytical Science</li> <li>Drug Discovery/ Drug Development/ Drug Substance</li> <li>Drug Safety/ Compound Safety</li> <li>Process Chemistry/ Process Development</li> <li>Product Characterisation/ Risk Assessment</li> <li>Pharmacokinetics/ Metabolism</li> <li>Extractables & Leachables</li> <li>API Development/ Degradation Products</li> <li>LC-MS/ Mass Spectrometry</li> <li>Good Laboratory Practice (GLP)/ Good Manufacturing Practice (GMP)</li> <li>Regulatory Affairs & Compliance</li> </ul> </div> </div> <div class="vc_empty_space" style="height: 32px"><span class="vc_empty_space_inner"></span></div></div></div></div></div><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_single_image wpb_content_element vc_align_center wpb_content_element"> <figure class="wpb_wrapper vc_figure"> <div class="vc_single_image-wrapper vc_box_border_grey"><img width="300" height="300" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="vc_single_image-img attachment-medium gt-lazy-load" alt="" title="" decoding="async" data-src="https://www.uventia.com/wp-content/uploads/2023/12/Agenda-3GTI-300x300.png?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/12/Agenda-3GTI-300x300.png 300w, https://www.uventia.com/wp-content/uploads/2023/12/Agenda-3GTI-150x150.png 150w, https://www.uventia.com/wp-content/uploads/2023/12/Agenda-3GTI-350x350.png 350w, https://www.uventia.com/wp-content/uploads/2023/12/Agenda-3GTI-85x85.png 85w, https://www.uventia.com/wp-content/uploads/2023/12/Agenda-3GTI-100x100.png 100w, https://www.uventia.com/wp-content/uploads/2023/12/Agenda-3GTI.png 500w" data-sizes="(max-width: 300px) 100vw, 300px" /></div> </figure> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h3>[<span style="color: #ffbb00">Agenda</span>] 3rd Annual Genotoxic Impurities Summit: Nitrosamines & Beyond 2023</h3> <p>Download the full summit program to find speaker biographies, case studies, key takeaways, the day's schedule, and details of each session.</p> </div> </div> <div class="gt-button gt-style-1 gt-align-right gt-inline-false gt-margin-false"><a data-toggle="modal" data-target="#modal-7698"><span>REQUEST BROCHURE</span></a></div><div class="modal fade gt-modal gt-large-modal gt-modal-button-modal" id="modal-7698" tabindex="-6" role="dialog" aria-labelledby="modal-7698-label"><div class="modal-dialog gt-modal-dialog modal-dialog-centered" role="document"><div class="modal-content gt-modal-content"><div class="modal-header gt-modal-header"><div 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/></a><div class="gt-event-status">Expired</div><div class="gt-price"><span></span>[•REC] - €295</div></div><div class="gt-title"><a href="https://www.uventia.com/event/2nd-annual-genotoxic-impurities-summit-nitrosamines-beyond-2022/">2nd Annual Genotoxic Impurities Summit: Nitrosamines & Beyond 2022</a></div><div class="gt-details"><div class="gt-category"><ul><li class="gt-category-30"><a href="https://www.uventia.com/event-category/pharma/?post_type=event">Pharma</a></li></ul></div><div class="gt-date gt-start-date"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><rect x="3" y="4" width="18" height="18" rx="2" ry="2"></rect><line x1="16" y1="2" x2="16" y2="6"></line><line x1="8" y1="2" x2="8" y2="6"></line><line x1="3" y1="10" x2="21" y2="10"></line></svg><span>December 1, 2022</span></div><div class="gt-location"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" 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Adamed Pharma S.A. ● Advanz Pharma ● AGES-MEA ● ALK-Abelló S.A. ● American Regent ● AMSlab ● Angelini Pharma S.p.A. ● APIs & NCE Manufacturing LeadAC Immune SA ● Aptuit an Evotec Company ● ARLANXEO Netherlands B.V ● Arrotex Pharmaceuticals Pty Ltd ● Astellas Pharma Europe BV ● Astellas Pharma Inc. ● AstraZeneca ● BD Technologies ● Boehringer Ingelheim Pharma GmbH & Co. KG ● Charles River Laboratories ● Chugai Pharmaceutical Co., Ltd. ● Croma-Pharma GmbH ● CSL Behring ● Dottikon Exclusive Synthesis AG ● EDQM, Council of Europe ● Excella GmbH & Co. KG ● FARMAK, a.s. ● Fermion Oy ● Fresenius Kabi ● Fresenius Kabi Deutschland GmbH ● FUJIFILM Toyama Chemical ● Gentronix Ltd ● Grunenthal Ecuatoriana Cia. Ltda. ● GSK ● Haleon ● Health and Environmental Sciences Institute (HESI) ● Hemofarm AD ● Hemomont d.o.o. ● Idorsia ● Insight Exposure and Risk Sciences ● Intertek ● Intertek Melbourn ● Intox Private Limited ● Intuitive Fluorescence Imaging, LLC ● Johnson&Johnson ● Konya Food and Agriculture University ● Krka d. d., Novo mesto ● L.Molteni & C. dei F.lli Alitti SpA ● LabAnalysis S.r.l. ● Laboratoires MAYOLY SPINDLER ● Labtim ADRIA d.o.o. ● LangAllan CMC Regulatory Solutions Ltd ● Lek Pharmaceuticals d.d. ● Lhasa Limited ● Lundbeck ● Luye Pharma AG ● Merck Healthcare KGaA ● Midas Pharma GmbH ● MultiCASE Inc ● National Institute of Health Sciences ● Norwich Pharmaceuticals ● Novartis ● Olon S.p.A. ● Orion Pharma ● Pfizer ● Pharmaceutical firm Darnitsa ● Polpharma ● Preclintox Services, LLC ● ProBioGen AG ● Rontis Hellas ● S-IN Soluzioni Informatiche ● Safetree Consulting e.U. ● Sanofi ● SEQENS ● Solvias AG ● State Agency of Medicines ● Swansea University ● Swissmedic ● Takeda ● Takeda Pharmaceuticals ● Tallinn University of Technology ● Teva Pharmaceutical Industries Ltd. ● TEVA Pharmaceutical Works Ltd ● Teva Pharmaceuticals ● ToxMinds BVBA ● UCB ● Vertex Pharmaceuticals ● Viatris ● Waters ● Waters Corporation ● Zakłady Farmaceutyczne Polpharma ● Zentiva Group, a.s.</p> </div> </div> </div></div><div class="vc_tta-panel" id="3-gti-4" data-vc-content=".vc_tta-panel-body"><div class="vc_tta-panel-heading"><h4 class="vc_tta-panel-title"><a href="#3-gti-4" data-vc-accordion data-vc-container=".vc_tta-container"><i class="vc_tta-icon vc-oi vc-oi-calendar"></i><span class="vc_tta-title-text">ATTENDEES IN 2022</span></a></h4></div><div class="vc_tta-panel-body"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p>● Adamed Pharma ● Lundbeck ● Astellas Pharma Europe B.V. ● Sanofi ● Dr. Reddy's Laboratories Limited ● Airnov Healthcare Packaging ● Egis Pharmaceuticals Plc. ● Waters Corporation ● Teva Pharmaceutical ● Synthon ● Synthon B.V. ● Polpharma ● Silence Therapeutics ● Menarini Ricerche ● Polpharma SA ● Krka ● Teva Pharmaceutical Industries Ltd ● Teva Active Pharmaceutical Ingredients ● Neurocrine Biosciences ● JSC Olainfarm ● Bibra toxicology advice & consulting Ltd ● Berlin-Chemie AG ● Janssen Pharmaceutica ● Jazz Pharmaceuticals ● Pliva Hrvatska d.o.o. ● Dr. Anika Schroeter e.U. ● Eurofins PSS ● Angelini Pharma S.p.A. ● Food and Drug Administration ● Astellas Pharma Europe ● Saneca Pharmaceuticals ● Teva Israel Ltd ● Arrotex Pty Ltd ● Merck Healthcare KGaA ● Boehringer Ingelheim Pharma GmbH & Co. KG ● Bracco Imaging SpA ● Perrigo ● Chiesi Farmaceutici SpA ● Advanz Pharma ● Midas Pharma GmbH ● Aptuit an Evotec Company ● Hikma Pharmaceuticals ● Aptuit (Verona) S.r.L., An Evotec Company ● Adamed Pharma S.A. ● fagg-afmps ● World Health Organization (WHO) ● Curia Spain S.A.U. ● Swissmedic ● Albhades ● Finnish Medicines Agency ● Selvita S.A. ● Fresenius Medical Care Deutschland GmbH ● Fresenius Kabi ● IFF ● Teva Ni Ltd ● Bayer AG ● FUJIFILM Toyama Chemical Co., Ltd. ● INEOS Oxide ● Affygility Solutions ● Laboratorium Zdrochem sp. z o.o. ● Zentiva, k.s. ● Janssen ● Bachem AG ● BD ● Jagiellonian Center of Innovation ● Sanofi Chimie ● Venn Life Sciences ● Merck KGaA, Darmstadt, Germany ● Teva Gyogyszergyar Zrt. ● Drug Development Solutions ● Senior Consultant ● Lonza AG ● Alliance Pharmaceuticals Ltd ● Minakem ● B. Braun Medical, S.A.U. ● Smith + Nephew ● Haleon ● LabExperts Sp. z o.o. ● Technologie Servier ● Ipca Laboratories Ltd. ● Recipharm Pharmaservices Pvt Ltd ● ANTIBIOTICE SA ● Pharmaceutical Firm Darnitsa ● Bausch Health ● Idorsia ● Pfizer ● Avivia ● Altox ● West Pharmaceutical Services ● GSK ● Novartis ● Teva Pharmaceuticals ● Lhasa Limited ● Gilead Sciences Inc. ● Amgen Inc. ● Sandoz ● Instem, Inc. ● Generapharm ● Pfizer Global R&D ● United States Pharmacopeia</p> </div> </div> </div></div><div class="vc_tta-panel" id="3-gti-5" data-vc-content=".vc_tta-panel-body"><div class="vc_tta-panel-heading"><h4 class="vc_tta-panel-title"><a href="#3-gti-5" data-vc-accordion data-vc-container=".vc_tta-container"><i class="vc_tta-icon vc-oi vc-oi-calendar"></i><span class="vc_tta-title-text">ATTENDEES IN 2021</span></a></h4></div><div class="vc_tta-panel-body"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p>● AB Sciex Pte. Ltd. ● Adamed Pharma S.A. ● Alkaloid Skopje ● Almirall S.A. ● Angelini Pharma ● AstraZeneca ● Bausch Health ● Bayer AG ● Becton Dickinson ● Bilim Pharmaceuticals ● Cambrex Profarmaco Milano sr ● Cehtra ● Chemsafe Srl ● Chiesi Farmaceutici SpA ● CPAM du Cher (Assurance Maladie) ● Croma-Pharma GmbH ● Curia Italy s.r.l. ● Dechra Pharmaceuticals Manufacturing ● Dexcel LTD ● Dottikon Exclusive Synthesis AG ● EDQM, Council of Europe ● ERBC srl ● Ever Valinject GmbH ● FUJIFILM Toyama Chemical Co., Ltd. ● Gilead Sciences Inc. ● Givaudan International SA ● GlaxoSmithKline Consumer Healthcare ● Halmed ● Health Care Solution ● Helsinn Advanced Synthesis SA ● Hemofarm AD ● Janssen ● Janssen R&D (J&J) ● JAZMP ● Johnson & Johnson ● L’Oreal ● Lek Pharmaceuticals d.d. ● LGCGroup ● Lhasa Limited ● Liverpool John Moores University ● Malta Medicines Authority ● Merck Healthcare KGaA ● Merck/Sigma Aldrich ● Moehs Iberica, SL ● Novartis ● Orion Corporation ● Pfizer HealthCare ● Pfizer LIMITED ● Polpharma ● PRO.MED. 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height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Gautier Decock" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/gautier-decock/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/gautier-decock/">Gautier Decock</a></div><div class="gt-profession">Managing Director of Seqens CRDO Business</div><div class="gt-company">SEQENS</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/gautierdecock-managingdirector/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/samuel-conway/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Samuel Conway" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/samuel-conway/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/samuel-conway/">Samuel Conway</a></div><div class="gt-profession">Staff Scientist II</div><div class="gt-company">BD Technologies</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/samuel-conway-phd/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/george-johnson/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="George Johnson" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/george-johnson/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/george-johnson/">George Johnson</a></div><div class="gt-profession">Associate Professor</div><div class="gt-company">Swansea University</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.swansea.ac.uk/staff/g.johnson/%20" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/alyssa-musso/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Alyssa Musso" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/alyssa-musso/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/alyssa-musso/">Alyssa Musso</a></div><div class="gt-profession">Senior Scientist, Drug Safety Research and Development</div><div class="gt-company">Pfizer</div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/andrew-poulton/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Andrew Poulton" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/andrew-poulton/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/andrew-poulton/">Andrew Poulton</a></div><div class="gt-profession">Associate Principal Scientist, Pharmaceutical Sciences</div><div class="gt-company">AstraZeneca</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/andrew-poulton-08865229b/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/andreas-czich/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Andreas Czich" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/andreas-czich/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/andreas-czich/">Andreas Czich</a></div><div class="gt-profession">Toxicologist, Senior Distinguished Scientist </div><div class="gt-company">Sanofi</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/andreas-czich-434b8742/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/mourad-rahi/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Mourad F. Rahi" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/mourad-rahi/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/mourad-rahi/">Mourad F. Rahi</a></div><div class="gt-profession">Senior Consultant Chemist</div><div class="gt-company">Preclintox Services, LLC</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/mourad-rahi-867b9014/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/avital-talya-milenkiy/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Avital Talya Milenkiy" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/avital-talya-milenkiy/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/avital-talya-milenkiy/">Avital Talya Milenkiy</a></div><div class="gt-profession">Chemical Toxicologist</div><div class="gt-company">Teva Pharmaceutical Industries Ltd.</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/avital-talya-m-811996216/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/leon-f-stankowski/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Leon F. Stankowski" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/leon-f-stankowski/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/leon-f-stankowski/">Leon F. Stankowski, Jr.</a></div><div class="gt-profession">Senior Scientific Director, Genetic and In Vitro Toxicology</div><div class="gt-company">Charles River Laboratories</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/leon-stankowski-3b2b6312" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/bruno-spieldenner/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Bruno Spieldenner" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/bruno-spieldenner/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/bruno-spieldenner/">Bruno Spieldenner</a></div><div class="gt-profession">Head of Division</div><div class="gt-company">EDQM, Council of Europe</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/brunospieldenner/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/jasmin-lott/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Jasmin Lott" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott.jpg 350w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/jasmin-lott/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/jasmin-lott/">Jasmin Lott</a></div><div class="gt-profession">Associate Director</div><div class="gt-company">Boehringer Ingelheim</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/jasmin-lott-b9b1051a2" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/susanne-glowienke/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Susanne Glowienke" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke.jpg 350w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/susanne-glowienke/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/susanne-glowienke/">Susanne Glowienke</a></div><div class="gt-profession">Head Impurity Safety</div><div class="gt-company">Novartis Pharma AG</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/susanne-glowienke-ab9644119/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/mike-urquhart/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Mike Urquhart" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart.jpg 350w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/mike-urquhart/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/mike-urquhart/">Mike Urquhart</a></div><div class="gt-profession">Scientific Director</div><div class="gt-company">GSK</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/mike-urquhart-401aa373/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/patrick-reichl/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Patrick Reichl" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl.jpg 350w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/patrick-reichl/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/patrick-reichl/">Patrick Reichl</a></div><div class="gt-profession">Toxicology Lead</div><div class="gt-company">Croma-Pharma GmbH</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/patrick-reichl-301a077b/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/reinhard-stidl/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Reinhard Stidl" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl.jpg 350w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/reinhard-stidl/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/reinhard-stidl/">Reinhard Stidl</a></div><div class="gt-profession">Senior Toxicologist - Managing Director</div><div class="gt-company">Safetree Consulting e.U.</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/reinhard-stidl-63658536/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/raphael-nudelman/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Raphael Nudelman" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman.jpg 350w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a 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class="gt-schedule-tabs nav" role="tablist"><li><a data-toggle="tab" class="active show" href="#gt-event-schedule-1" role="tab" aria-controls="gt-event-schedule-1" aria-selected="true">November 30</a></li><li><a data-toggle="tab" href="#gt-event-schedule-2" role="tab" aria-controls="gt-event-schedule-2" aria-selected="true">December 1</a></li></ul><div class="gt-dropdown"><div class="tab-content"><div class="tab-pane fade active show" id="gt-event-schedule-1" role="tabpanel" aria-labelledby="nav-gt-event-schedule-1-tab"><div class="gt-panel-group" id="event-schedule-accardion-693087" role="tablist" aria-multiselectable="true"><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-308057"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-308057" aria-expanded="true" aria-controls="event-schedule-collapse-308057"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">09:30 - 09:40</div><div class="gt-title">✍ REGISTRATION</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-308057" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-308057"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-336051"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-336051" aria-expanded="true" aria-controls="event-schedule-collapse-336051"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">09:50</div><div class="gt-title">Revisiting the landscape of complex nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-336051" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-336051"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Examining how the CPCA has changed the regulatory landscape for nitrosamines.</p> <p><span style="color: #ff9900">◆ </span> Impact on drug manufacturers.</p> <p><span style="color: #ff9900">◆ </span> Areas that require further understanding and evolution.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Lhasa-Limited-130x60.png?x97293" alt="Lhasa-Limited" width="130" height="60" /><span class="su-custom-gallery-title">Lhasa-Limited</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.lhasalimited.org/">Lhasa Limited</a>, UK</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/michael-burns/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Michael Burns" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Michael Burns</div><div class="gt-profession">Principal Research Scientist</div><div class="gt-company">Lhasa Limited</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-303042"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-303042" aria-expanded="true" aria-controls="event-schedule-collapse-303042"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">10:30</div><div class="gt-title">The EDQM response to nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-303042" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-303042"><div class="gt-panel-body"><div class="gt-text"><p>The presentation will start with a short overview of the EDQM and how it fits in the European regulatory system. </p> <p>The historical evolution from the outbreak of nitrosamines in June 2018 to today and the actions taken on the EU/EC/EMA regulatory level as well as at EDQM will be provided. </p> <p>Finally, the EDQM response to nitrosamines will be provided by detailing the actions undertaken and still ongoing within the three main tracks that are: the texts of the European Pharmacopoeia, the testing of batchs within the Official Medicines Control Laboratories and the Certification (CEP) procedure.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/10/EDQM-Council-of-Europe-130x60.png?x97293" alt="EDQM,-Council-of-Europe" width="130" height="60" /><span class="su-custom-gallery-title">EDQM,-Council-of-Europe</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.edqm.eu/en/" target="_blank" rel="noopener">EDQM, Council of Europe</a>, FR</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/bruno-spieldenner/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Bruno Spieldenner" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/07/Bruno-Spieldenner.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Bruno Spieldenner</div><div class="gt-profession">Head of Division</div><div class="gt-company">EDQM, Council of Europe</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-216778"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-216778" aria-expanded="true" aria-controls="event-schedule-collapse-216778"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">11:10</div><div class="gt-title">Management of N-nitrosamines and their risk assessment within GSK R&D</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-216778" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-216778"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> How N-nitrosamines might form within DS and DP and how to assess.</p> <p><span style="color: #ff9900">◆ </span> Experiences of Step 2 testing.</p> <p><span style="color: #ff9900">◆ </span> Steps taken when an N-nitrosamine and/or N-nitroso drug substance related impurity (NDSRI) is confirmed.</p> <p><span style="color: #ff9900">◆ </span> How GSK are assessing risk in R&D.</p> <p><span style="color: #ff9900">◆ </span> Reflections and looking forward.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/12/GSK-130x60.png?x97293" alt="GSK" width="130" height="60" /><span class="su-custom-gallery-title">GSK</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.gsk.com/en-gb/" target="_blank" rel="noopener">GSK</a>, UK</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/mike-urquhart/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Mike Urquhart" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Mike Urquhart</div><div class="gt-profession">Scientific Director</div><div class="gt-company">GSK</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-685814"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-685814" aria-expanded="true" aria-controls="event-schedule-collapse-685814"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">12:00</div><div class="gt-title">Setting limits for NDSRIs</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-685814" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-685814"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Misalignments between ICH M7 and regulatory requirements for nitrosamines.</p> <p><span style="color: #ff9900">◆ </span> Difficulty in setting acceptable intake (AI) levels for nitrosamine drug substance related impurities (NDSRIs).</p> <p><span style="color: #ff9900">◆ </span> Proposals for AIs of nitrosamines of classes of drugs - position papers for nitrosamines of calcium channel blockers, beta-blockers and beta-agonist, and ACE inhibitors.</p> <p><span style="color: #ff9900">◆ </span> Use of in vivo mutagenicity data to categorize the potency of NDSRIs.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/08/TEVA-130x60.png?x97293" alt="TEVA" width="130" height="60" /><span class="su-custom-gallery-title">TEVA</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.tevapharm.com/" target="_blank" rel="noopener">Teva Pharmaceutical Industries Ltd.</a>, IL</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/raphael-nudelman/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Raphael Nudelman" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Raphael Nudelman</div><div class="gt-profession">Chemical Toxicologist</div><div class="gt-company">Nudelman ChemTox Consulting</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-149786"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-149786" aria-expanded="true" aria-controls="event-schedule-collapse-149786"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">12:40</div><div class="gt-title">Using genetic toxicity data to support risk assessment of nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-149786" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-149786"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> In vivo mutation and cancer potency.</p> <p><span style="color: #ff9900">◆ </span> Using in vivo mutation data to support potency categorisation.</p> <p><span style="color: #ff9900">◆ </span> Next steps and upcoming data sets and approaches.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2023/09/Swansea-University-130x60.png?x97293" alt="Swansea-University" width="130" height="60" /><span class="su-custom-gallery-title">Swansea-University</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.swansea.ac.uk/" target="_blank" rel="noopener">Swansea University</a>, UK</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/george-johnson/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="George Johnson" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">George Johnson</div><div class="gt-profession">Associate Professor</div><div class="gt-company">Swansea University</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-874954"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-874954" aria-expanded="true" aria-controls="event-schedule-collapse-874954"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">13:10 - 14:10</div><div class="gt-title">🍴Lunch Break</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-874954" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-874954"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-492134"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-492134" aria-expanded="true" aria-controls="event-schedule-collapse-492134"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">14:10</div><div class="gt-title">Nitrosamines, industry perspective</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-492134" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-492134"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Understanding of the evolution of the issue – Valsartan to NDSRIs. </p> <p><span style="color: #ff9900">◆ </span> Current risks – progress against deadlines. </p> <p><span style="color: #ff9900">◆ </span> Areas of uncertainty and their impact.</p> <p><span style="color: #ff9900">◆ </span> Where will we be in 12 months times.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/02/AstraZeneca-130x60.png?x97293" alt="AstraZeneca" width="130" height="60" /><span class="su-custom-gallery-title">AstraZeneca</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.astrazeneca.com/" target="_blank" rel="noopener">AstraZeneca</a>, UK</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/andrew-poulton/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Andrew Poulton" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/11/Andrew-Poulton.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Andrew Poulton</div><div class="gt-profession">Associate Principal Scientist, Pharmaceutical Sciences</div><div class="gt-company">AstraZeneca</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-278325"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-278325" aria-expanded="true" aria-controls="event-schedule-collapse-278325"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">14:50</div><div class="gt-title">Setting acceptable intakes (AIS) for complex nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-278325" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-278325"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Categorizing and deriving AIs for complex API-like nitrosamines.</p> <p><span style="color: #ff9900">◆ </span> Two to three specific case studies providing examples of how AIs were derived based on experimental data.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Pfizer-130x60.png?x97293" alt="Pfizer" width="130" height="60" /><span class="su-custom-gallery-title">Pfizer</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.pfizer.com/" target="_blank" rel="noopener">Pfizer</a>, USA</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/alyssa-musso/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Alyssa Musso" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/09/Alyssa-Musso.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Alyssa Musso</div><div class="gt-profession">Senior Scientist, Drug Safety Research and Development</div><div class="gt-company">Pfizer</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-745103"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-745103" aria-expanded="true" aria-controls="event-schedule-collapse-745103"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">15:30</div><div class="gt-title">Toxicological assessment of nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-745103" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-745103"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Mutagenicity and Carcinogenicity of Nitrosamines.</p> <p><span style="color: #ff9900">◆ </span> Mechanisms.</p> <p><span style="color: #ff9900">◆ </span> Differences between small molecular weight Nitrosamines and NDSRI.</p> <p><span style="color: #ff9900">◆ </span> The LTL concept.</p> <p><span style="color: #ff9900">◆ </span> Using SAR, QM and Metabolism data to support AI.</p> <p><span style="color: #ff9900">◆ </span> Improving the adherence to ICH M7.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Sanofi-130x60.png?x97293" alt="Sanofi" width="130" height="60" /><span class="su-custom-gallery-title">Sanofi</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.sanofi.com/en" target="_blank" rel="noopener">Sanofi</a>, DE</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/andreas-czich/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Andreas Czich" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/09/Andreas-Czich.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Andreas Czich</div><div class="gt-profession">Toxicologist, Senior Distinguished Scientist </div><div class="gt-company">Sanofi</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-25738"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-25738" aria-expanded="true" aria-controls="event-schedule-collapse-25738"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">16:10</div><div class="gt-title">🔒 [Speaker Sponsor] Nitrosamine Drug Substance -Related Impurities Management at SEQENS</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-25738" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-25738"><div class="gt-panel-body"><div class="gt-text"><p style="font-weight: 400"><span style="color: #ff9900">◆ </span> Risk Assessment Approach.</p> <p style="font-weight: 400"><span style="color: #ff9900">◆ </span> Analytical Screening & Identification of NDSRIs.</p> <p style="font-weight: 400"><span style="color: #ff9900">◆ </span> Toxicological Qualifications.</p> <p style="font-weight: 400"><span style="color: #ff9900">◆ </span> Quantification of Ultra-Traces NDSRIs.</p> <p style="font-weight: 400"><span style="color: #ff9900">◆ </span> Control Strategy.</p> <p style="font-weight: 400"><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2023/06/SEQENS-130x60.png?x97293" alt="SEQENS" width="130" height="60" /><span class="su-custom-gallery-title">SEQENS</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.seqens.com/" target="_blank" rel="noopener">Seqens</a>, FR</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/gautier-decock/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Gautier Decock" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/11/Gautier-Decock.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Gautier Decock</div><div class="gt-profession">Managing Director of Seqens CRDO Business</div><div class="gt-company">SEQENS</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-129239"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-129239" aria-expanded="true" aria-controls="event-schedule-collapse-129239"><div class="gt-inner"><div class="gt-date">November 30, 2023</div><div class="gt-time">16:40 - 16:50</div><div class="gt-title">🎤 Chairman’s closing remarks and end of day one</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-129239" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-129239"><div class="gt-panel-body"></div></div></div></div></div><div class="tab-pane fade" id="gt-event-schedule-2" role="tabpanel" aria-labelledby="nav-gt-event-schedule-2-tab"><div class="gt-panel-group" id="event-schedule-accardion-693087" role="tablist" aria-multiselectable="true"><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-63435"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-63435" aria-expanded="true" aria-controls="event-schedule-collapse-63435"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">10:50 - 11:10</div><div class="gt-title">✍ REGISTRATION</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-63435" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-63435"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-898410"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-898410" aria-expanded="true" aria-controls="event-schedule-collapse-898410"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">11:10</div><div class="gt-title">In silico evaluations to assess mutagenicity of impurities</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-898410" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-898410"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> QSAR approaches to detect structural alerts.</p> <p><span style="color: #ff9900">◆ </span> Read-across approaches to assess prediction results.</p> <p><span style="color: #ff9900">◆ </span> In vivo/in vitro genotoxicity studies assessing genotoxicity.</p> <h6><a href="https://www.novartis.com/" target="_blank" rel="noopener">Novartis</a>, CH</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/susanne-glowienke/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Susanne Glowienke" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2022/08/Susanne-Glowienke.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Susanne Glowienke</div><div class="gt-profession">Head Impurity Safety</div><div class="gt-company">Novartis Pharma AG</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-191957"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-191957" aria-expanded="true" aria-controls="event-schedule-collapse-191957"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">11:50</div><div class="gt-title">ICH M7 approaches in peptides that are developed as NCEs</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-191957" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-191957"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> ICH M7 has to be followed for peptides developed as NCEs.</p> <p><span style="color: #ff9900">◆ </span> (Q)SAR predictions following ICH M7 lead to class 3 readouts in many structures.</p> <p><span style="color: #ff9900">◆ </span> Using a &bdquo;substructure“ approach might help there.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/02/Boehringer-Ingelheim-130x60.png?x97293" alt="Boehringer-Ingelheim" width="130" height="60" /><span class="su-custom-gallery-title">Boehringer-Ingelheim</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.boehringer-ingelheim.com/" target="_blank" rel="noopener">Boehringer Ingelheim Pharma GmbH & Co. KG</a>, DE</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/jasmin-lott/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Jasmin Lott" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/07/Jasmin-Lott.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Jasmin Lott</div><div class="gt-profession">Associate Director</div><div class="gt-company">Boehringer Ingelheim</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-510316"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-510316" aria-expanded="true" aria-controls="event-schedule-collapse-510316"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">12:30</div><div class="gt-title">Genotoxic impurities in medical devices</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-510316" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-510316"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Regulatory framework for GIs in Medical Devices.</p> <p><span style="color: #ff9900">◆ </span> Recent developments (ISO 10993-17:2023).</p> <p><span style="color: #ff9900">◆ </span> Case studies.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/09/croma_est1976-130x60.png?x97293" alt="croma_est1976" width="130" height="60" /><span class="su-custom-gallery-title">croma_est1976</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.cromapharma.com/uk?url=/home-en/" target="_blank" rel="noopener">Croma-Pharma GmbH</a>, AT</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/patrick-reichl/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Patrick Reichl" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Patrick Reichl</div><div class="gt-profession">Toxicology Lead</div><div class="gt-company">Croma-Pharma GmbH</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-499311"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-499311" aria-expanded="true" aria-controls="event-schedule-collapse-499311"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">13:00 - 14:00</div><div class="gt-title">🍴Lunch Break</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-499311" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-499311"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-75294"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-75294" aria-expanded="true" aria-controls="event-schedule-collapse-75294"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">14:00</div><div class="gt-title">Extractables and leachables - potential genotoxic impurities?</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-75294" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-75294"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Different regulatory expectations on toxicological risk assessments for different classes of impurities.</p> <p><span style="color: #ff9900">◆ </span> Potential E&L genotoxicity - impact of route of administration on Threshold of Toxicological Concern.</p> <p><span style="color: #ff9900">◆ </span> Hazard characterization of identified and not identified extractables and leachables.</p> <p><span style="color: #ff9900">◆ </span> Assessment of data poor substances: (Q)SARs and read-across.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Safetree-Consulting-130x60.png?x97293" alt="Safetree-Consulting" width="130" height="60" /><span class="su-custom-gallery-title">Safetree-Consulting</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.safetree.at/" target="_blank" rel="noopener">Safetree Consulting e.U.</a>, AT</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/reinhard-stidl/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Reinhard Stidl" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Reinhard Stidl</div><div class="gt-profession">Senior Toxicologist - Managing Director</div><div class="gt-company">Safetree Consulting e.U.</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-599182"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-599182" aria-expanded="true" aria-controls="event-schedule-collapse-599182"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">14:40</div><div class="gt-title">Expert analysis and in-silico qsar methodologies to assess the mutagenicity potential of impurities</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-599182" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-599182"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Different methodologies applied for a comprehensive mutagenicity assessment.</p> <p><span style="color: #ff9900">◆ </span> Case studies presenting the overall assessment of impurities associated with QSAR: equivocal predictions, inconsistent in silico predictions, unclassified, misclassified and out of domain chemical moieties.</p> <p><span style="color: #ff9900">◆ </span> Analyzing the in vitro Ames test results, in order to provide mutagenicity assessment based on experimental data.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/08/TEVA-130x60.png?x97293" alt="TEVA" width="130" height="60" /><span class="su-custom-gallery-title">TEVA</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.tevapharm.com/" target="_blank" rel="noopener">Teva Pharmaceutical Industries Ltd.</a>, IL</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/avital-talya-milenkiy/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Avital Talya Milenkiy" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/08/Avital-Talya-Milenkiy.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Avital Talya Milenkiy</div><div class="gt-profession">Chemical Toxicologist</div><div class="gt-company">Teva Pharmaceutical Industries Ltd.</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-115114"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-115114" aria-expanded="true" aria-controls="event-schedule-collapse-115114"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">15:20</div><div class="gt-title">Toxicological risk assessment, ISO certification, compliance, art and sciences of chemical characterization of nitrosamines. Are we doing the right thing?</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-115114" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-115114"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Ambiguity of guidelines for drugs vs medical devices for calculation of Analytical Evaluation Threshold (AET) for toxicological risk assessment.</p> <p><span style="color: #ff9900">◆ </span> Effect of solvent selection and concentration of extracts on impurities profiling.</p> <p><span style="color: #ff9900">◆ </span> Chromatographic and spectroscopic skills in mass spectra interpretation for identification of Nitrosamines in screening modes.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2023/08/Preclintox-Services-LLC-130x60.png?x97293" alt="Preclintox-Services,-LLC" width="130" height="60" /><span class="su-custom-gallery-title">Preclintox-Services,-LLC</span></a></div><div class="su-clear"></div></div></p> <h6>Preclintox Services, LLC, USA</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/mourad-rahi/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Mourad F. Rahi" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/08/Mourad-F.-Rahi.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Mourad F. Rahi</div><div class="gt-profession">Senior Consultant Chemist</div><div class="gt-company">Preclintox Services, LLC</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-946942"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-946942" aria-expanded="true" aria-controls="event-schedule-collapse-946942"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">16:00</div><div class="gt-title">An update on the ongoing efforts to optimize the ames assay by the hesigttc mechanism-based genotoxicity risk assessment (MGRA) nitrosamine subgroup</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-946942" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-946942"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> Workgroup members and organization.</p> <p><span style="color: #ff9900">◆ </span> Key protocol features and rationale.</p> <p><span style="color: #ff9900">◆ </span> Comparison of metabolic activation conditions and results to date.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Charles-River-Laboratories-130x60.png?x97293" alt="Charles-River-Laboratories" width="130" height="60" /><span class="su-custom-gallery-title">Charles-River-Laboratories</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.criver.com/" target="_blank" rel="noopener">Charles River Laboratories</a>, USA</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/leon-f-stankowski/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Leon F. Stankowski" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Leon F. Stankowski, Jr.</div><div class="gt-profession">Senior Scientific Director, Genetic and In Vitro Toxicology</div><div class="gt-company">Charles River Laboratories</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-771976"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-771976" aria-expanded="true" aria-controls="event-schedule-collapse-771976"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">16:40</div><div class="gt-title">Challenges encountered during the attempted quantification of nitrosodimethylamine (NDMA) in rubber using traditional extraction techniques</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-771976" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-771976"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span> The analysis of nitrosamines in drug products is well studied, but little is reported regarding the content of nitrosamines in pharmaceutical rubber.</p> <p><span style="color: #ff9900">◆ </span> Highly inconsistent results were obtained using traditional extraction techniques to evaluate the content of nitrosodimethylamine (NDMA) in rubber.</p> <p><span style="color: #ff9900">◆ </span> Evidence suggests that NDMA is formed in situ during (and after) extraction.</p> <p><span style="color: #ff9900">◆ </span> NDMA may not be present in the rubber in its native form, but may be generated by attempts to detect it.</p> <p><div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2023/11/Becton-Dickinson-130x60.png?x97293" alt="Becton-Dickinson" width="130" height="60" /><span class="su-custom-gallery-title">Becton-Dickinson</span></a></div><div class="su-clear"></div></div></p> <h6><a href="https://www.bd.com/en-us" target="_blank" rel="noopener">BD Technologies</a>, USA</h6> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/samuel-conway/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Samuel Conway" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-85x85.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/11/Samuel-Conway.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Samuel Conway</div><div class="gt-profession">Staff Scientist II</div><div class="gt-company">BD Technologies</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-578375"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-693087" href="#event-schedule-collapse-578375" aria-expanded="true" aria-controls="event-schedule-collapse-578375"><div class="gt-inner"><div class="gt-date">December 1, 2023</div><div class="gt-time">17:10 - 17:20</div><div class="gt-title">🎤 Chairman’s closing remarks and end of day two</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-578375" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-578375"><div class="gt-panel-body"></div></div></div></div></div></div></div></div></div><div class="vc_empty_space" style="height: 32px"><span class="vc_empty_space_inner"></span></div><div class="gt-button gt-style-2 gt-align-center gt-inline-false gt-margin-false"><a href="https://www.uventia.com/register-now-for-3rd-annual-genotoxic-impurities-summit-nitrosamines-beyond-2023/" target="_parent"><i class="fa-solid fa-video"></i><span>BUY RECORDINGS</span></a></div></div></div></div></div></p> </div></div></div></div> </div> <div class="col-md-4 col-sm-12 col-xs-12 gt-site-right gt-fixed-sidebar"><div class="theiaStickySidebar"> <div class="gt-show-desktop"><div class="gt-widget gt-detail-widget"><div class="gt-widget-title"><span>Event Details</span></div><div class="gt-widget-content"><div class="gt-content-detail-box"><ul><li class="gt-start-date"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59 59" xml:space="preserve"> <g> <path d="M51.179,40.429l-5.596,8.04l-3.949-3.241c-0.426-0.352-1.057-0.288-1.407,0.138c-0.351,0.427-0.289,1.058,0.139,1.407 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c0.023,0.008,0.045,0.017,0.068,0.025c0.345,0.118,0.685,0.253,1.022,0.406C54.347,37.729,57,41.557,57,46 C57,52.065,52.065,57,46,57z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Start Date</div><div class="gt-inner">November 30, 2023 9:30 am</div></div></li><li class="gt-end-date"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59 59" xml:space="preserve"> <g> <path d="M50.95,41.13c-0.391-0.391-1.023-0.391-1.414,0L46,44.666l-3.536-3.536c-0.391-0.391-1.023-0.391-1.414,0 s-0.391,1.023,0,1.414l3.536,3.536l-3.536,3.536c-0.391,0.391-0.391,1.023,0,1.414c0.195,0.195,0.451,0.293,0.707,0.293 s0.512-0.098,0.707-0.293L46,47.494l3.536,3.536c0.195,0.195,0.451,0.293,0.707,0.293s0.512-0.098,0.707-0.293 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<g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">End Date</div><div class="gt-inner">December 1, 2023 5:20 pm</div></div></li><li class="gt-status"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 52 52" xml:space="preserve"> <g> <path d="M26,0C11.664,0,0,11.663,0,26s11.664,26,26,26s26-11.663,26-26S40.336,0,26,0z M26,50C12.767,50,2,39.233,2,26 S12.767,2,26,2s24,10.767,24,24S39.233,50,26,50z"/> <path d="M38.252,15.336l-15.369,17.29l-9.259-7.407c-0.43-0.345-1.061-0.274-1.405,0.156c-0.345,0.432-0.275,1.061,0.156,1.406 l10,8C22.559,34.928,22.78,35,23,35c0.276,0,0.551-0.114,0.748-0.336l16-18c0.367-0.412,0.33-1.045-0.083-1.411 C39.251,14.885,38.62,14.922,38.252,15.336z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Status</div><div class="gt-inner"><div class="gt-event-status">Expired</div></div></div></li><li class="gt-locations"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 54.757 54.757" xml:space="preserve"> <g> <path d="M27.557,12c-3.859,0-7,3.141-7,7s3.141,7,7,7s7-3.141,7-7S31.416,12,27.557,12z M27.557,24c-2.757,0-5-2.243-5-5 s2.243-5,5-5s5,2.243,5,5S30.314,24,27.557,24z"/> <path d="M40.94,5.617C37.318,1.995,32.502,0,27.38,0c-5.123,0-9.938,1.995-13.56,5.617c-6.703,6.702-7.536,19.312-1.804,26.952 L27.38,54.757L42.721,32.6C48.476,24.929,47.643,12.319,40.94,5.617z M41.099,31.431L27.38,51.243L13.639,31.4 C8.44,24.468,9.185,13.08,15.235,7.031C18.479,3.787,22.792,2,27.38,2s8.901,1.787,12.146,5.031 C45.576,13.08,46.321,24.468,41.099,31.431z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Location</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/location/online/?post_type=event">Online</a></li></ul></div></div></li><li class="gt-ticket-price"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59.997 59.997" style="enable-background:new 0 0 59.997 59.997;" xml:space="preserve"> <g> <path d="M19.519,21.05c-0.39,0.4-0.38,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.391,0.39-1.021,0-1.41C20.539,20.66,19.908,20.66,19.519,21.05z"/> <path d="M16.668,46.56c-0.39,0.391-0.39,1.03,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.29 c0.39-0.39,0.39-1.029,0-1.42C17.688,46.17,17.059,46.17,16.668,46.56z"/> <path d="M16.708,23.89c-0.39,0.391-0.39,1.03,0,1.42c0.2,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.39,0.38-1.03-0.01-1.41C17.729,23.5,17.088,23.5,16.708,23.89z"/> <path d="M19.499,49.39c-0.39,0.391-0.39,1.03,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.29 c0.39-0.39,0.39-1.029,0-1.42C20.519,49,19.888,49,19.499,49.39z"/> <path d="M25.118,52.28c-0.38,0.399-0.37,1.029,0.02,1.409c0.2,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.72-0.31 c0.38-0.39,0.38-1.021-0.02-1.41C26.138,51.88,25.508,51.88,25.118,52.28z"/> <path d="M22.338,18.21c-0.39,0.399-0.39,1.03,0.01,1.42c0.19,0.189,0.44,0.29,0.7,0.29c0.26,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.39-1.021-0.01-1.41C23.358,17.819,22.729,17.819,22.338,18.21z"/> <path d="M22.328,52.22c-0.39,0.39-0.39,1.021,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.29 c0.39-0.399,0.39-1.03,0-1.42S22.708,51.83,22.328,52.22z"/> <path d="M13.888,26.729c-0.39,0.391-0.39,1.03,0.01,1.42c0.19,0.19,0.44,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.3 c0.39-0.39,0.39-1.02-0.01-1.41C14.908,26.34,14.278,26.34,13.888,26.729z"/> <path d="M8.178,38.08c-0.39,0.39-0.39,1.02,0,1.41c0.2,0.199,0.45,0.3,0.71,0.3c0.26,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.39-1.021,0-1.41C9.208,37.689,8.568,37.689,8.178,38.08z"/> <path d="M8.258,32.41c-0.39,0.399-0.39,1.029,0,1.42c0.2,0.189,0.45,0.29,0.71,0.29c0.25,0,0.51-0.101,0.7-0.301 c0.39-0.39,0.39-1.02,0-1.409C9.278,32.02,8.638,32.02,8.258,32.41z"/> <path d="M5.438,35.25c-0.39,0.399-0.39,1.03,0,1.42c0.2,0.189,0.45,0.29,0.71,0.29c0.25,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.38-1.021-0.01-1.41C6.458,34.859,5.828,34.859,5.438,35.25z"/> <path d="M25.158,15.37c-0.39,0.399-0.39,1.029,0,1.42c0.2,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.72-0.3 c0.38-0.391,0.38-1.021-0.01-1.41C26.178,14.979,25.539,14.979,25.158,15.37z"/> <path d="M11.008,40.91c-0.39,0.39-0.39,1.02,0,1.409c0.2,0.2,0.45,0.29,0.71,0.29c0.25,0,0.51-0.09,0.71-0.29 c0.39-0.39,0.39-1.02,0-1.409C12.028,40.52,11.398,40.52,11.008,40.91z"/> <path d="M13.838,43.74c-0.39,0.39-0.39,1.02,0,1.409c0.2,0.2,0.45,0.29,0.71,0.29c0.25,0,0.51-0.09,0.7-0.29 c0.39-0.39,0.39-1.02,0-1.409C14.858,43.35,14.229,43.35,13.838,43.74z"/> <path d="M11.068,29.569c-0.39,0.4-0.38,1.03,0.01,1.421c0.19,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.301 c0.39-0.39,0.39-1.02-0.01-1.41C12.088,29.18,11.458,29.18,11.068,29.569z"/> <path d="M30.708,46.55c-0.39,0.39-0.38,1.03,0.02,1.41c0.19,0.189,0.44,0.28,0.69,0.28c0.26,0,0.52-0.101,0.72-0.301 c0.38-0.39,0.38-1.029-0.02-1.409C31.729,46.14,31.088,46.149,30.708,46.55z"/> <path d="M44.658,32.22c-0.39,0.39-0.38,1.03,0.02,1.41c0.19,0.189,0.44,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.3 c0.39-0.4,0.38-1.04-0.02-1.42C45.678,31.81,45.048,31.819,44.658,32.22z"/> <path d="M39.078,37.95c-0.39,0.399-0.38,1.029,0.02,1.409c0.19,0.19,0.44,0.29,0.69,0.29c0.26,0,0.52-0.1,0.72-0.3 c0.39-0.399,0.38-1.04-0.02-1.42C40.098,37.54,39.458,37.55,39.078,37.95z"/> <path d="M41.868,35.09c-0.39,0.39-0.38,1.02,0.02,1.41c0.19,0.189,0.44,0.28,0.69,0.28c0.27,0,0.53-0.101,0.72-0.301 c0.39-0.399,0.38-1.029-0.02-1.41C42.888,34.68,42.249,34.689,41.868,35.09z"/> <path d="M47.448,29.35c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.7,0.28c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C48.468,28.95,47.828,28.96,47.448,29.35z"/> <circle cx="50.499" cy="19" r="1"/> <path d="M27.918,49.41c-0.39,0.399-0.38,1.029,0.02,1.42c0.19,0.189,0.44,0.279,0.69,0.279c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.399,0.38-1.029-0.02-1.41C28.928,49.01,28.298,49.02,27.918,49.41z"/> <circle cx="50.499" cy="27" r="1"/> <circle cx="50.499" cy="23" r="1"/> <path d="M33.499,43.68c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C34.508,43.28,33.878,43.29,33.499,43.68z"/> <path d="M39.918,9c0-0.55-0.45-1-1-1c-0.56,0-1,0.45-1,1s0.44,1,1,1C39.468,10,39.918,9.55,39.918,9z"/> <path d="M27.968,12.53c-0.39,0.39-0.38,1.029,0.01,1.42c0.19,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.301 c0.39-0.39,0.39-1.02,0-1.409C28.988,12.14,28.358,12.14,27.968,12.53z"/> <path d="M30.789,9.689c-0.39,0.4-0.39,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.3 c0.39-0.39,0.39-1.02-0.01-1.41C31.809,9.3,31.178,9.3,30.789,9.689z"/> <path d="M34.918,8c-0.56,0-1,0.45-1,1s0.44,1,1,1c0.55,0,1-0.45,1-1S35.468,8,34.918,8z"/> <path d="M36.289,40.819c-0.39,0.391-0.38,1.03,0.02,1.41c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.391,0.38-1.03-0.02-1.41C37.309,40.41,36.668,40.42,36.289,40.819z"/> <path d="M59.206,0.293c-0.391-0.391-1.023-0.391-1.414,0L54.084,4H30.802L1.532,33.511c-0.667,0.666-1.034,1.553-1.034,2.495 s0.367,1.829,1.034,2.495l20.466,20.466c0.687,0.687,1.588,1.03,2.491,1.03c0.906,0,1.814-0.346,2.508-1.04l28.501-29.271V5.414 l3.707-3.707C59.596,1.316,59.596,0.684,59.206,0.293z M53.499,28.874L25.574,57.553c-0.595,0.596-1.565,0.596-2.162,0 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<path d="M48.014,42.889l-9.553-4.776C37.56,37.662,37,36.756,37,35.748v-3.381c0.229-0.28,0.47-0.599,0.719-0.951 c1.239-1.75,2.232-3.698,2.954-5.799C42.084,24.97,43,23.575,43,22v-4c0-0.963-0.36-1.896-1-2.625v-5.319 c0.056-0.55,0.276-3.824-2.092-6.525C37.854,1.188,34.521,0,30,0s-7.854,1.188-9.908,3.53C17.724,6.231,17.944,9.506,18,10.056 v5.319c-0.64,0.729-1,1.662-1,2.625v4c0,1.217,0.553,2.352,1.497,3.109c0.916,3.627,2.833,6.36,3.503,7.237v3.309 c0,0.968-0.528,1.856-1.377,2.32l-8.921,4.866C8.801,44.424,7,47.458,7,50.762V54c0,4.746,15.045,6,23,6s23-1.254,23-6v-3.043 C53,47.519,51.089,44.427,48.014,42.889z M51,54c0,1.357-7.412,4-21,4S9,55.357,9,54v-3.238c0-2.571,1.402-4.934,3.659-6.164 l8.921-4.866C23.073,38.917,24,37.354,24,35.655v-4.019l-0.233-0.278c-0.024-0.029-2.475-2.994-3.41-7.065l-0.091-0.396l-0.341-0.22 C19.346,23.303,19,22.676,19,22v-4c0-0.561,0.238-1.084,0.67-1.475L20,16.228V10l-0.009-0.131c-0.003-0.027-0.343-2.799,1.605-5.021 C23.253,2.958,26.081,2,30,2c3.905,0,6.727,0.951,8.386,2.828c1.947,2.201,1.625,5.017,1.623,5.041L40,16.228l0.33,0.298 C40.762,16.916,41,17.439,41,18v4c0,0.873-0.572,1.637-1.422,1.899l-0.498,0.153l-0.16,0.495c-0.669,2.081-1.622,4.003-2.834,5.713 c-0.297,0.421-0.586,0.794-0.837,1.079L35,31.623v4.125c0,1.77,0.983,3.361,2.566,4.153l9.553,4.776 C49.513,45.874,51,48.28,51,50.957V54z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Organizer</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/event-organizer/uventia/?post_type=event">Uventia</a></li></ul></div></div></li><li class="gt-categories"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 60 60" xml:space="preserve"> <path d="M57.49,21.5H54v-6.268c0-1.507-1.226-2.732-2.732-2.732H26.515l-5-7H2.732C1.226,5.5,0,6.726,0,8.232v43.687l0.006,0 c-0.005,0.563,0.17,1.114,0.522,1.575C1.018,54.134,1.76,54.5,2.565,54.5h44.759c1.156,0,2.174-0.779,2.45-1.813L60,24.649v-0.177 C60,22.75,58.944,21.5,57.49,21.5z M2,8.232C2,7.828,2.329,7.5,2.732,7.5h17.753l5,7h25.782c0.404,0,0.732,0.328,0.732,0.732V21.5 H12.731c-0.144,0-0.287,0.012-0.426,0.036c-0.973,0.163-1.782,0.873-2.023,1.776L2,45.899V8.232z M47.869,52.083 c-0.066,0.245-0.291,0.417-0.545,0.417H2.565c-0.243,0-0.385-0.139-0.448-0.222c-0.063-0.082-0.16-0.256-0.123-0.408l10.191-27.953 c0.066-0.245,0.291-0.417,0.545-0.417H54h3.49c0.38,0,0.477,0.546,0.502,0.819L47.869,52.083z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Category</div><div class="gt-inner"><ul><li><a 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data-srcset="https://www.uventia.com/wp-content/uploads/2024/03/Genotoxic-Impurities-Nitrosamines-Beyond-952x579.jpg 952w, https://www.uventia.com/wp-content/uploads/2024/03/Genotoxic-Impurities-Nitrosamines-Beyond-130x80.jpg 130w" data-sizes="auto, (max-width: 952px) 100vw, 952px" /></a></div><div class="gt-content"><div class="gt-title"><a href="https://www.uventia.com/event/4th-annual-genotoxic-impurities-summit-nitrosamines-beyond-2024/">4th Annual Genotoxic Impurities Summit: Nitrosamines & Beyond 2024</a></div><div class="gt-details"><div class="gt-category"><ul><li class="gt-category-30"><a href="https://www.uventia.com/event-category/pharma/?post_type=event">Pharma</a></li></ul></div><div class="gt-date gt-start-date"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><rect x="3" y="4" width="18" height="18" rx="2" ry="2"></rect><line x1="16" y1="2" x2="16" y2="6"></line><line x1="8" y1="2" x2="8" y2="6"></line><line x1="3" y1="10" x2="21" y2="10"></line></svg><span>December 4, 2024</span></div><div class="gt-time gt-start-time"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><circle cx="12" cy="12" r="10"></circle><polyline points="12 6 12 12 16 14"></polyline></svg><span>11:50 am</span></div></div><div class="gt-text">We are planning to hold an online meeting with subject matter experts to evaluate different points of view on how to solve the problems associated with mutagenic impurities.</div><div class="gt-details"><div class="gt-status"><svg fill="currentColor" version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 512 512" xml:space="preserve"> <g transform="translate(1 1)"> <g> <g> <path 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0h-472c-11.046875 0-20 8.953125-20 20v275.335938c0 11.042968 8.953125 20 20 20h472c11.046875 0 20-8.957032 20-20v-275.335938c0-11.046875-8.953125-20-20-20zm-118.324219 275.335938h-235.351562c-8.453125-50.175782-48.148438-89.871094-98.324219-98.324219v-38.6875c50.175781-8.453125 89.871094-48.148438 98.324219-98.324219h235.351562c8.453125 50.175781 48.148438 89.871094 98.324219 98.324219v38.6875c-50.175781 8.453125-89.871094 48.148437-98.324219 98.324219zm98.324219-177.867188c-28.070312-7.25-50.21875-29.398438-57.46875-57.46875h57.46875zm-374.53125-57.46875c-7.25 28.070312-29.398438 50.21875-57.46875 57.46875v-57.46875zm-57.46875 177.867188c28.070312 7.25 50.21875 29.394531 57.46875 57.46875h-57.46875zm374.53125 57.46875c7.25-28.074219 29.398438-50.21875 57.46875-57.46875v57.46875zm-158.53125-216.335938c-54.40625 0-98.667969 44.261719-98.667969 98.667969 0 54.402343 44.261719 98.667969 98.667969 98.667969s98.667969-44.265626 98.667969-98.667969c0-54.40625-44.261719-98.667969-98.667969-98.667969zm0 157.335938c-32.347656 0-58.667969-26.320313-58.667969-58.667969 0-32.351563 26.320313-58.667969 58.667969-58.667969s58.667969 26.316406 58.667969 58.667969c0 32.347656-26.320313 58.667969-58.667969 58.667969zm0 0"/></svg><span><span></span>€415 - €595</span></div></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-event-style-4" data-event-id="9756"><div class="gt-image"><div class="gt-label gt-style-2 gt-position-top-left gt-label-9756"><a href="https://www.uventia.com/registration-5th-annual-extractables-leachables-summit-2025/" target="http://_self">DISCOUNT 25%</a></div><a href="https://www.uventia.com/event/5th-annual-extractables-leachables-summit-2025/"><img width="952" height="579" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-event-list size-eventchamp-event-list gt-lazy-load wp-post-image" alt="" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2024/09/5_Extractables_Leachables-952x579.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2024/09/5_Extractables_Leachables-952x579.jpg 952w, https://www.uventia.com/wp-content/uploads/2024/09/5_Extractables_Leachables-130x80.jpg 130w" data-sizes="auto, (max-width: 952px) 100vw, 952px" /></a></div><div class="gt-content"><div class="gt-title"><a href="https://www.uventia.com/event/5th-annual-extractables-leachables-summit-2025/">5th Annual Extractables & Leachables Summit 2025</a></div><div class="gt-details"><div class="gt-category"><ul><li class="gt-category-30"><a href="https://www.uventia.com/event-category/pharma/?post_type=event">Pharma</a></li></ul></div><div class="gt-date gt-start-date"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><rect x="3" y="4" width="18" height="18" rx="2" ry="2"></rect><line x1="16" y1="2" x2="16" y2="6"></line><line x1="8" y1="2" x2="8" y2="6"></line><line x1="3" y1="10" x2="21" y2="10"></line></svg><span>February 27, 2025</span></div><div class="gt-time gt-start-time"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><circle cx="12" cy="12" r="10"></circle><polyline points="12 6 12 12 16 14"></polyline></svg><span>11:50 am</span></div></div><div class="gt-text">Participate in our event to learn about the latest methods for testing and analyzing Extractables and Leachables.</div><div class="gt-details"><div class="gt-status"><svg fill="currentColor" version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 512 512" xml:space="preserve"> <g transform="translate(1 1)"> <g> <g> <path d="M447,468.333h-42.667v-82.325c0-35.684-17.822-68.993-47.505-88.755l-63.366-42.249l63.377-42.241 c0.658-0.44,1.294-0.906,1.941-1.359c0.359-0.25,0.72-0.498,1.075-0.753c0.564-0.406,1.122-0.818,1.677-1.234 c0.723-0.54,1.436-1.09,2.143-1.646c0.287-0.227,0.58-0.448,0.864-0.678c25.025-20.114,39.794-50.621,39.794-83.1V41.667H447 c11.782,0,21.333-9.551,21.333-21.333C468.333,8.551,458.782-1,447-1h-64H127H63C51.218-1,41.667,8.551,41.667,20.333 c0,11.782,9.551,21.333,21.333,21.333h42.667v82.325c0,32.472,14.762,62.973,39.785,83.093c0.278,0.225,0.564,0.441,0.845,0.663 c0.724,0.57,1.455,1.134,2.196,1.687c0.532,0.398,1.066,0.793,1.606,1.181c0.431,0.309,0.868,0.61,1.304,0.913 c0.583,0.406,1.153,0.827,1.745,1.222l63.393,42.252l-63.38,42.258c-29.671,19.754-47.493,53.063-47.493,88.747v82.325H63 c-11.782,0-21.333,9.551-21.333,21.333S51.218,511,63,511h64h256h64c11.782,0,21.333-9.551,21.333-21.333 S458.782,468.333,447,468.333z M338.079,173.622c-0.06,0.049-0.12,0.097-0.18,0.146c-0.56,0.456-1.135,0.895-1.712,1.331 c-0.423,0.318-0.848,0.633-1.28,0.942c-0.081,0.058-0.164,0.115-0.246,0.173c-0.488,0.345-0.98,0.686-1.479,1.018L255,229.36 l-78.171-52.12c-0.457-0.304-0.906-0.617-1.354-0.932c-0.143-0.101-0.287-0.2-0.429-0.301c-0.41-0.294-0.815-0.593-1.217-0.896 c-0.588-0.445-1.173-0.892-1.744-1.356c-0.07-0.056-0.138-0.113-0.207-0.17c-1.513-1.241-2.966-2.547-4.352-3.918h174.948 C341.074,171.051,339.608,172.37,338.079,173.622z M361.667,41.667v82.325c0,1.006-0.031,2.009-0.078,3.008H148.412 c-0.047-0.999-0.078-2.002-0.078-3.008V41.667H361.667z M148.333,468.333v-82.325c0-21.416,10.689-41.392,28.484-53.24 l62.684-41.794c3.887,4.114,9.382,6.692,15.499,6.692c6.118,0,11.612-2.578,15.499-6.692l62.672,41.786 c17.807,11.855,28.496,31.832,28.496,53.248v82.325H148.333z"/> <path d="M255,383c11.797,0,21.333-9.536,21.333-21.333v-21.333c0-11.797-9.536-21.333-21.333-21.333 c-11.797,0-21.333,9.536-21.333,21.333v21.333C233.667,373.464,243.203,383,255,383z"/> <path d="M255.213,404.333H255c-11.797,0-21.227,9.536-21.227,21.333S243.437,447,255.213,447 c11.776,0,21.333-9.536,21.333-21.333S266.989,404.333,255.213,404.333z"/> </g> </g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg><div class="gt-event-status">Upcoming</div></div><div class="gt-location"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><path d="M21 10c0 7-9 13-9 13s-9-6-9-13a9 9 0 0 1 18 0z"></path><circle cx="12" cy="10" r="3"></circle></svg><ul><li class="gt-category-141"><a href="https://www.uventia.com/location/online/?post_type=event">Online</a></li></ul></div><div class="gt-price"><svg fill="currentColor" viewBox="0 -98 512 512" xmlns="https://www.w3.org/2000/svg"><path d="m492 0h-472c-11.046875 0-20 8.953125-20 20v275.335938c0 11.042968 8.953125 20 20 20h472c11.046875 0 20-8.957032 20-20v-275.335938c0-11.046875-8.953125-20-20-20zm-118.324219 275.335938h-235.351562c-8.453125-50.175782-48.148438-89.871094-98.324219-98.324219v-38.6875c50.175781-8.453125 89.871094-48.148438 98.324219-98.324219h235.351562c8.453125 50.175781 48.148438 89.871094 98.324219 98.324219v38.6875c-50.175781 8.453125-89.871094 48.148437-98.324219 98.324219zm98.324219-177.867188c-28.070312-7.25-50.21875-29.398438-57.46875-57.46875h57.46875zm-374.53125-57.46875c-7.25 28.070312-29.398438 50.21875-57.46875 57.46875v-57.46875zm-57.46875 177.867188c28.070312 7.25 50.21875 29.394531 57.46875 57.46875h-57.46875zm374.53125 57.46875c7.25-28.074219 29.398438-50.21875 57.46875-57.46875v57.46875zm-158.53125-216.335938c-54.40625 0-98.667969 44.261719-98.667969 98.667969 0 54.402343 44.261719 98.667969 98.667969 98.667969s98.667969-44.265626 98.667969-98.667969c0-54.40625-44.261719-98.667969-98.667969-98.667969zm0 157.335938c-32.347656 0-58.667969-26.320313-58.667969-58.667969 0-32.351563 26.320313-58.667969 58.667969-58.667969s58.667969 26.316406 58.667969 58.667969c0 32.347656-26.320313 58.667969-58.667969 58.667969zm0 0"/></svg><span><span></span>€415 - €595</span></div></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-event-style-4" data-event-id="2925"><div class="gt-image"><a href="https://www.uventia.com/event/combination-products-summit-2025/"><img width="952" height="579" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-event-list size-eventchamp-event-list gt-lazy-load wp-post-image" alt="Combination Products Summit" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2020/11/Combination-Products-Summit-952x579.jpg?x97293" data-srcset="https://www.uventia.com/wp-content/uploads/2020/11/Combination-Products-Summit-952x579.jpg 952w, https://www.uventia.com/wp-content/uploads/2020/11/Combination-Products-Summit-130x80.jpg 130w" data-sizes="auto, (max-width: 952px) 100vw, 952px" /></a></div><div class="gt-content"><div class="gt-title"><a href="https://www.uventia.com/event/combination-products-summit-2025/">Combination Products Integrated Development Summit 2025</a></div><div class="gt-details"><div class="gt-category"><ul><li class="gt-category-30"><a href="https://www.uventia.com/event-category/pharma/?post_type=event">Pharma</a></li></ul></div><div class="gt-date gt-start-date"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><rect x="3" y="4" width="18" height="18" rx="2" ry="2"></rect><line x1="16" y1="2" x2="16" y2="6"></line><line x1="8" y1="2" x2="8" y2="6"></line><line x1="3" y1="10" x2="21" y2="10"></line></svg><span>April 24, 2025</span></div><div class="gt-time gt-start-time"><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><circle cx="12" cy="12" r="10"></circle><polyline points="12 6 12 12 16 14"></polyline></svg><span>10:00 am</span></div></div><div class="gt-text">What are critical considerations on drug-device integrated development and how to choose the right regulatory and clinical strategy?</div><div class="gt-details"><div class="gt-status"><svg fill="currentColor" version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 512 512" xml:space="preserve"> <g transform="translate(1 1)"> <g> <g> <path d="M447,468.333h-42.667v-82.325c0-35.684-17.822-68.993-47.505-88.755l-63.366-42.249l63.377-42.241 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