Information requirements

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href="/regulations/prior-informed-consent/explicit-consent-requirement">Explicit consent requirement</a></li> </ul> </div>  <div class="MMCol MMCol-6"> <p class="MMHeading MMReg MMPIC">lists of Chemicals subject to pic </p> <ul> <li><a href="/information-on-chemicals/pic/chemicals">Chemicals subject to PIC</a></li> <li><a href="/information-on-chemicals/pic/export-notifications">Export notifications</a></li> <li><a href="/information-on-chemicals/pic/import-notifications">Import notifications</a></li> <li><a href="https://staging-production-2.echa.europa.eu/information-on-chemicals/pic/explicit-consents">Explicit consent</a></li> </ul>   <div class="HighlightedLink"><a href="/euclef"><img alt="EUCLEF" src="/documents/10162/24132/magnifier_sm/e06259a2-e46c-46db-afc1-086f66bc9588?t=1322245350109" /> EUCLEF<span class="fieldNameHasTooltip" title="EU Chemicals Legislation Finder (EUCLEF): find information on other EU chemicals legislation"><img 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</a></li> <li><a href="/opinions-of-the-committee-for-risk-assessment-on-proposals-for-harmonised-classification-and-labelling" title="RAC opinions on proposals for harmonised classification and labelling ">Harmonised classification and labelling (RAC) </a></li> <li><a href="/regulations/biocidal-products-regulation/approval-of-active-substances/bpc-opinions-on-active-substance-approval" title="BPC opinions on active substance approval">Active substance approval (BPC)</a></li> <li><a href="/bpc-opinions-on-union-authorisation" title="BPC opinions on Union authorisation">Union Authorisation (BPC)</a></li> <li><a href="/oels-activity-list" title="RAC opinions on occupational exposure limits">OEL (RAC)</a></li> <li><a href="/about-us/who-we-are/committee-for-risk-assessment/opinions-of-the-rac-adopted-under-specific-echa-s-executive-director-requests" title="RAC opinions under specific ECHA's Executive Director requests">Executive Director request (RAC)</a></li> <li><a href="/opinions-of-the-seac-adopted-under-specific-echa-s-executive-director-requests" title="SEAC opinions under specific ECHA's Executive Director requests">Executive Director request (SEAC)</a></li> <li><a href="/about-us/who-we-are/member-state-committee/opinions-of-the-msc-adopted-under-specific-echa-s-executive-director-requests" title="MSC opinions under specific ECHA's Executive Director requests">Executive Director request (MSC)</a></li> </ul> </div> <p class="MMAll"><a href="/information-on-chemicals" title="View all">View all</a></p> </div> </div> </li> <li class="OtherNavItem"> <a class="SiteNav" href="/support"> <span class="VAlignMiddle">Support</span> </a> <div class="MegaMenu"> <div class="MMCol MMCol-4"> <p class="MMDescription">The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation.</p> <p class="MMHeading MMReg MMREACH">REACH</p> <ul> <li><a 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href="https://echa.europa.eu/revocation-and-invalidity-of-registration-decisions"> Revocation and invalidity of registration decisions </a> </li> </ul> </li> </ul> </div> </div> </div> </div> </section> </div> </div> </div> <div class="TCol-6 tpl-w528 portlet-column MainContent" id="column-2"> <h2 class="page-title"> <span>Information requirements</span> </h2> <div class="portlet-dropzone portlet-column-content" id="layout-column_column-2"> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_5pDf_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_5pDf"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_5pDf"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10087-13534" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="13532" data-analytics-asset-title="Information requirements" data-analytics-asset-type="web-content"> <p>REACH registration requires information on intrinsic properties of a substance. Companies manufacturing and importing chemicals in the EU/EEA are responsible for the safe use of their products. As registrants, they need to assess if their chemicals may cause adverse effects to human health and the environment. This is done based on reliable test results or by alternative information which is scientifically justified.</p> <p>The REACH Regulation requires registrants to prepare a registration dossier. This is composed of <strong>a technical dossier</strong> and, where relevant, a <strong>chemical safety report,</strong> which summarises the results of a chemical safety assessment. A chemical safety report is only required if the registrant manufactures or imports a substance in quantities of 10 tonnes or more a year.</p> <p>Before compiling their joint registration dossier, registrants first need to evaluate all available data on the intrinsic properties of a substance. Only when this data is not adequate to meet the requirements of REACH, may additional testing be needed. However, before testing on vertebrate animals, use of alternative methods and all other options must be considered (Article 13 of REACH).</p> <p>The <strong>standard information requirements</strong> are those which are required as a minimum to meet the registration obligations of REACH. They depend on the quantity of the substance that is manufactured or imported into the EU/EEA and are described in Annexes VI to X to REACH. These minimum data requirements may be adapted as appropriate. This means that certain tests may be waived.</p> <p>Registrants of the same substance have to share information which is required for the registration. To avoid unnecessary animal testing and duplication of tests, study results from tests involving vertebrate animals must be shared between registrants.</p> <h3>Gathering all existing information</h3> <p>Registrants are required to collect all physicochemical, toxicological and ecotoxicological information that is relevant and available to them on the substance they are registering (regardless of whether information on a given endpoint is required or not at the specific tonnage level). To be able to use the information for registration, companies should have permission for it.</p> <p>In addition, the registrant should collect information on the use, exposure and risk management measures of the substance they are registering.</p> <p>Further information is provided in the <em>Guidance on Information Requirements, R.2, section R.2.2, and R.3</em>.</p> <h3>Identifying the standard information requirements</h3> <p>Each registrant needs to identify their information requirements according to the tonnage level in which they manufacture or import the substance, based on REACH Annexes VII to X.</p> <p>The standard requirements can vary depending on whether the following apply to the substance:</p> <p style="margin-left: 40px;">(i) specific cases for registering substances from 1 to 10 tonnes per year: if you can show that your substance has a predicted low risk, you can benefit from reduced information requirements.</p> <p style="margin-left: 40px;">(ii) specific criteria as provided in column 2 of Annexes VII to X</p> <p style="margin-left: 40px;">(iii) general criteria for adaptation of information requirements given in Annex XI.</p> <p>Registrants must use existing information and non-test methods to meet their information requirements. Testing on vertebrate animals should only be used as a last resort. Studies for information requirements on ecotoxicity, toxicity and physical-chemical properties should be generated using test guidelines approved by the OECD and EU.</p> <p>Below you can find a simplified list of the <strong>standard information requirements</strong>. The full list of information requirements is provided in the <em>Guidance on Registration (section 4.1)</em>.  </p> <p><em>Note: these lists may be subject to changes as REACH annexes are updated or new methodologies become available.</em></p> <p class="clear-header"> </p> <div class="lfr-panel lfr-collapsible lfr-collapsed lfr-extended echa-panel" id="first"> <div class="lfr-panel-titlebar"> <div class="lfr-panel-title">Information requirements: 1-10 tonnes a year</div> </div> <div class="lfr-panel-content"> <p>For the lowest tonnage band, the information required is specified in Column 1 of REACH Annex VII, comprising certain physico-chemical data, toxicological information and ecotoxicological information.</p> <p class="clear-header"> </p> <table class="template-table"> <tbody> <tr> <th colspan="2" style="text-align: center;">Information required for standard registration of 1-10 tonnes a year<br /> (Annex VII of REACH)</th> </tr> <tr> <td style="text-align: center; width: 50%"><strong>Non-vertebrate animal endpoints</strong></td> <td style="text-align: center;"><strong>Vertebrate animal endpoints</strong></td> </tr> <tr> <td>Description of the state of the substance at 20°C / 101.3 kPa</td> <td>Acute toxicity: oral</td> </tr> <tr> <td>Melting/freezing point</td> <td> </td> </tr> <tr> <td>Boiling point (if applicable)</td> <td> </td> </tr> <tr> <td>Relative density</td> <td> </td> </tr> <tr> <td>Vapour pressure (if applicable)</td> <td> </td> </tr> <tr> <td>Surface tension (if applicable)</td> <td> </td> </tr> <tr> <td>Water solubility</td> <td> </td> </tr> <tr> <td>Partition coefficient</td> <td> </td> </tr> <tr> <td>Flash-point</td> <td> </td> </tr> <tr> <td>Flammability</td> <td> </td> </tr> <tr> <td>Explosive properties</td> <td> </td> </tr> <tr> <td>Self-ignition temperature</td> <td> </td> </tr> <tr> <td>Oxidising properties</td> <td> </td> </tr> <tr> <td height="27">Granulometry (if applicable)</td> <td> </td> </tr> <tr> <td><em>In vitro</em> skin irritation/corrosion</td> <td> </td> </tr> <tr> <td><em>In vitro</em> eye irritation</td> <td> </td> </tr> <tr> <td>Skin sensitisation</td> <td> </td> </tr> <tr> <td><em>In vitro</em> gene mutation in bacteria</td> <td> </td> </tr> <tr> <td>Short-term toxicity on invertebrates</td> <td> </td> </tr> <tr> <td>Growth inhibition study aquatic plants</td> <td> </td> </tr> <tr> <td>Ready biodegradability (if applicable)</td> <td> </td> </tr> </tbody> </table> <p class="clear-footer"> </p> </div> </div> <div class="lfr-panel lfr-collapsible lfr-collapsed lfr-extended echa-panel" id="second"> <div class="lfr-panel-titlebar"> <div class="lfr-panel-title">Information requirements: 10-100 tonnes a year</div> </div> <div class="lfr-panel-content"> <p class="clear-header"> </p> <table class="template-table"> <tbody> <tr> <th colspan="2" style="text-align: center;"><strong>Information required for standard registration of 10-100 tonnes a year<br /> (Annex VIII of REACH)</strong><br /> <em>Note: this is to be provided in addition to the information which is listed in Annex VII.</em></th> </tr> <tr> <td style="text-align: center;"><strong>Non-vertebrate animal endpoints</strong></td> <td style="text-align: center;"><strong>Vertebrate animal endpoints</strong></td> </tr> <tr> <td><em>In vitro</em> mutagenicity study in mammalian cells or<em> In</em> <em>vitro</em> micronucleus study</td> <td><em>In vivo</em> skin irritation*</td> </tr> <tr> <td><em>In vitro</em> gene mutation in mammalian cells</td> <td><em>In vivo</em> eye irritation*</td> </tr> <tr> <td>Activated sludge respiration inhibition test</td> <td>Testing proposal for <em>in vivo</em> genotoxicity (if one of the <em>in vitro </em>tests is positive)</td> </tr> <tr> <td>Degradation</td> <td>Acute toxicity: inhalation </td> </tr> <tr> <td>Hydrolysis</td> <td><span style="line-height: 16.7999992370605px;">Short-term repeated dose toxicity (28-day)</span></td> </tr> <tr> <td rowspan="3">Adsorption/desorption screening</td> <td><span style="line-height: 16.7999992370605px;">Screening for reproductive/developmental toxicity</span></td> </tr> <tr> <td> <p style="line-height: 16.7999992370605px;">Short-term toxicity on fish<br /> or<br /> Testing proposal for long-term toxicity on fish (if the substance is poorly water soluble)</p> </td> </tr> </tbody> </table> <p font="size=90%">* You are allowed to do an in vivo study only if you are not able to classify your substance based on the in vitro results.</p> <p class="clear-footer"> </p> <p class="clear-footer"> </p> </div> </div> <div class="lfr-panel lfr-collapsible lfr-collapsed lfr-extended echa-panel" id="third"> <div class="lfr-panel-titlebar"> <div class="lfr-panel-title">Information requirements: 100 to 1000 tonnes a year</div> </div> <div class="lfr-panel-content"> <p class="clear-header"> </p> <table class="template-table"> <tbody> <tr> <th colspan="2" style="text-align: center;"><strong>Information required for standard registration of 100-1000 tonnes a year<br /> (Annex IX of REACH)</strong><br /> <em>Note: this is to be provided in addition to the information which is listed in Annexes VII and VIII. </em></th> </tr> <tr> <td style="text-align: center;"><strong>Non-vertebrate animal endpoints</strong></td> <td style="text-align: center;"><strong>Vertebrate animal endpoints</strong></td> </tr> <tr> <td>Stability in organic solvents</td> <td>Sub-chronic toxicity (90 days)</td> </tr> <tr> <td>Dissociation constant</td> <td>Pre-natal developmental toxicity in one species</td> </tr> <tr> <td>Viscosity</td> <td>Extended One-Generation Reproductive Toxicity (if triggered)</td> </tr> <tr> <td>Long-term aquatic toxicity on invertebrates</td> <td>Long-term aquatic toxicity on fish </td> </tr> <tr> <td>Degradation</td> <td>Bioaccumulation in aquatic species</td> </tr> </tbody> </table> <p class="clear-footer"> </p> </div> </div> <p class="clear-footer"> </p> <div class="lfr-panel lfr-collapsible lfr-collapsed lfr-extended echa-panel" id="fourth"> <div class="lfr-panel-titlebar"> <div class="lfr-panel-title">Information requirements: 1000 tonnes or more a year</div> </div> <div class="lfr-panel-content"> <p class="clear-header"> </p> <table class="template-table"> <tbody> <tr> <th colspan="2" style="text-align: center;"><strong>Information required for standard registration of 1000 tonnes or more a year (Annex X of REACH) </strong><br /> <br /> <em>Note: this is to be provided in addition to the information which is listed in Annexes VII, VIII and IX. </em></th> </tr> <tr> <td style="text-align: center;"><strong>Non-vertebrate animal endpoints</strong></td> <td style="text-align: center;"><strong>Vertebrate animal endpoints</strong></td> </tr> <tr> <td>Further degradation testing</td> <td>Long-term repeated dose toxicity (≥ 12 months) if triggered</td> </tr> <tr> <td colspan="1" rowspan="3">Long-term toxicity to sediment organisms</td> <td>Developmental toxicity in a second species</td> </tr> <tr> <td>Extended One-Generation Reproductive Toxicity</td> </tr> <tr> <td>Carcinogenicity if triggered</td> </tr> </tbody> </table> <p class="clear-footer"> </p> </div> </div> <h3>Chemical safety report</h3> <p>A chemical safety report (CSR) is required for all substances subject to registration in quantities of 10 tonnes a year or more per registrant. The CSR documents the chemical safety assessment performed as part of the REACH registration process.  </p> <p>The chemical safety assessment results in the following outputs:</p> <ul style="margin-left: 40px;"> <li>Assessment of any hazards</li> <li>Identification of the conditions under which the risks from the manufacture and uses are under control, i.e. exposure scenarios</li> <li>Documentation of relevant data, justifications and conclusions in a chemical safety report</li> <li>Communication down the supply chain</li> </ul> <h3>Information requirements for intermediates</h3> <p>The information requirements for intermediates are generally reduced and there is no requirement to carry out a chemical safety assessment.</p> <p>To fulfil the definition of an intermediate, the registered substance needs to be transformed into another substance and manufactured and used under strictly controlled conditions at chemical manufacturing sites. The status of a substance as an intermediate is not specific to its chemical nature but to how it is used after manufacture.</p> <p>Consequently, the following two conditions must be met:</p> <ul style="margin-left: 40px;"> <li>The use of the substance meets the definition of an intermediate as described in REACH Article 3(15) and further explained in the <em>Guidance on intermediates</em>; and</li> <li>The substance is manufactured and/or used under strictly controlled conditions.</li> </ul> <p>Further information on intermediates and the information requirements for intermediates is available in the <em>Practical Guide: How to assess whether a substance is used as an intermediate under strictly controlled conditions and how to report the information for the intermediate registration in IUCLID</em>.</p> </div> </div> </div> </div> </div> </section> </div> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_O5uB_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_O5uB"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_O5uB"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10087-118421" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="118419" data-analytics-asset-title="Information requirements - related documents" data-analytics-asset-type="web-content"> <div class="Related"> <div class="RelatedTitle">Related</div>  <ul> <li><a href="/guidance-documents/guidance-on-information-requirements-and-chemical-safety-assessment">Guidance on information requirements and chemical safety assessment</a> <span class="comment">(Pathfinder)</span></li> <li><a href="http://echa.europa.eu/documents/10162/2324906/nutshell_guidance_csa_en.pdf/8fe6c700-fae0-45de-809a-dfae85485c25" target="_blank">Guidance in a nutshell on chemical safety assessment</a><span class="comment"> [PDF] [EN]</span></li> <li><a href="http://echa.europa.eu/documents/10162/2324906/registration_en.pdf/de54853d-e19e-4528-9b34-8680944372f2" target="_blank">Guidance on registration</a><span class="comment"> [PDF] [EN]</span></li> <li><a href="http://echa.europa.eu/documents/10162/2324906/nutshell_guidance_registration_en.pdf/9fda505f-972d-4bbb-b22c-bd71b6941571" target="_blank">Guidance in a nutshell on registration</a><span class="comment"> [PDF] [EN]</span></li> <li><a href="/documents/10162/2324906/intermediates_en.pdf/0386199a-bdc5-4bbc-9548-0d27ac222641" target="_blank">Guidance on intermediates</a> <span class="comment">[PDF] [EN]</span></li> <li><a href="http://echa.europa.eu/documents/10162/2324906/substance_id_en.pdf/ee696bad-49f6-4fec-b8b7-2c3706113c7d" target="_blank">Guidance for identification and naming of substances under REACH</a> <span class="comment">[PDF] [EN]</span></li> <li><a href="http://echa.europa.eu/documents/10162/2324906/nutshell_guidance_substance_en.pdf/cca556cd-4f68-4b38-a29b-58cb6da31a93" target="_blank">Guidance in a nutshell on identification and naming of substances under REACH and CLP</a></li> <li><a href="/practical-guides">CLP Practical Guide: How to assess whether a substance is used as an intermediate under strictly controlled conditions and how to report the information for the intermediate registration in IUCLID</a></li> </ul> </div> <p class="clear-header"> </p> </div> </div> </div> </div> </div> </section> </div> </div> <div class="TCol-9 tpl-w204 portlet-column portlet-column-last" id="column-4"> </div> </div> <div class="TCol-3 tpl-w204 portlet-column" id="column-3"> <div class="SideBar"> <div class="portlet-dropzone portlet-column-content portlet-column-content-last" id="layout-column_column-3"> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_vE1T_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_vE1T"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_vE1T"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10087-722058" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="722056" data-analytics-asset-title="Information requirements - support" data-analytics-asset-type="web-content"> <div class="img-width-100"> <h3> See also under the <em>Support</em> section</h3> <div class="Img"> <img alt="Image" src="/documents/10162/24133/info_blue_lg+1.png/c82c3425-79d3-4288-9474-ba767ba92a90" style="width: 45px; height: 45px;" /></div> <div class="Content" style="padding:0px;"> <div class="plain_link_list"> <ul> <li> <a href="/support/registration/what-information-you-need-to-submit">What information you need to submit?</a></li> <li> <a href="/support/testing-methods-and-alternatives">Testing methods and alternatives</a></li> </ul> </div> </div> <p class="clear-footer">  </p> </div> </div> </div> </div> </div> </div> </section> </div> <div class="portlet-boundary portlet-boundary_com_liferay_journal_content_web_portlet_JournalContentPortlet_ portlet-static portlet-static-end portlet-barebone portlet-journal-content " id="p_p_id_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_m9GA_"> <span id="p_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_m9GA"></span> <section class="portlet" id="portlet_com_liferay_journal_content_web_portlet_JournalContentPortlet_INSTANCE_m9GA"> <div class="portlet-content"> <div class="autofit-float autofit-row portlet-header"> <div class="autofit-col autofit-col-end"> <div class="autofit-section"> <div class="visible-interaction"> </div> </div> </div> </div> <div class=" portlet-content-container"> <div class="portlet-body"> <div class="" data-fragments-editor-item-id="10087-962070" data-fragments-editor-item-type="fragments-editor-mapped-item" > <div class="journal-content-article " data-analytics-asset-id="962068" data-analytics-asset-title="Information requirements - 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Liferay.Portlet.register('com_liferay_site_navigation_site_map_web_portlet_SiteNavigationSiteMapPortlet_INSTANCE_Lt0p'); Liferay.Portlet.onLoad( { canEditTitle: false, columnPos: 0, isStatic: 'end', namespacedId: 'p_p_id_com_liferay_site_navigation_site_map_web_portlet_SiteNavigationSiteMapPortlet_INSTANCE_Lt0p_', portletId: 'com_liferay_site_navigation_site_map_web_portlet_SiteNavigationSiteMapPortlet_INSTANCE_Lt0p', refreshURL: '\x2fc\x2fportal\x2frender_portlet\x3fp_l_id\x3d11554\x26p_p_id\x3dcom_liferay_site_navigation_site_map_web_portlet_SiteNavigationSiteMapPortlet_INSTANCE_Lt0p\x26p_p_lifecycle\x3d0\x26p_t_lifecycle\x3d0\x26p_p_state\x3dnormal\x26p_p_mode\x3dview\x26p_p_col_id\x3dcolumn-1\x26p_p_col_pos\x3d0\x26p_p_col_count\x3d1\x26p_p_isolated\x3d1\x26currentURL\x3d\x252Fregulations\x252Freach\x252Fregistration\x252Finformation-requirements', refreshURLData: {} } ); Liferay.Loader.require('metal-dom/src/all/dom', function(metalDomSrcAllDom) { (function(){ var dom = metalDomSrcAllDom; (function() {var $ = AUI.$;var _ = AUI._; var focusInPortletHandler = dom.delegate( document, 'focusin', '.portlet', function(event) { dom.addClasses(dom.closest(event.delegateTarget, '.portlet'), 'open'); } ); var focusOutPortletHandler = dom.delegate( document, 'focusout', '.portlet', function(event) { dom.removeClasses(dom.closest(event.delegateTarget, '.portlet'), 'open'); } ); })();})(); });AUI().use('liferay-menu', 'liferay-notice', 'aui-base', 'liferay-session', 'liferay-poller', function(A) {(function() {var $ = AUI.$;var _ = AUI._; if (A.UA.mobile) { Liferay.Util.addInputCancel(); } })();(function() {var $ = AUI.$;var _ = AUI._; new Liferay.Menu(); var liferayNotices = Liferay.Data.notices; for (var i = 1; i < liferayNotices.length; i++) { new Liferay.Notice(liferayNotices[i]); } })();(function() {var $ = AUI.$;var _ = AUI._; Liferay.Session = new Liferay.SessionBase( { autoExtend: true, redirectOnExpire: false, redirectUrl: 'https\x3a\x2f\x2fecha\x2eeuropa\x2eeu\x2fweb\x2fguest', sessionLength: 900, sessionTimeoutOffset: 70, warningLength: 0 } ); })();}); // ]]> </script> <script src="https://echa.europa.eu/o/echa-revamp-theme/js/main.js?browserId=ie&minifierType=js&languageId=en_GB&t=1732504048000" type="text/javascript"></script>   <div id="SiteMessages" style="display:none;"> <div class="SiteMessage SiteMessageWarning explorer-outdated-warning" style="display:none"> <p> Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.</p> <p> <button class="btn CloseSiteMessage btn-primary btn-default" id="explorerOutdatedWarningCloseButton" name="explorerOutdatedWarningCloseButton" onClick="closeWarningMessage(); return false;" type="submit" > <span class="lfr-btn-label">Close</span> </button> <label> <input type="checkbox" name="toggleExplorerOutdatedWarningCheckbox" id="toggleExplorerOutdatedWarningCheckbox" class="aui-field-input aui-field-input-choice" checked="checked"> Do not show this message again </label> </p> </div> <div class="SiteMessage SiteMessageCookies" id="CookieNotification" style="display:none;"> <p>This website uses cookies to ensure you get the best experience on our websites.</p> <p> <button class="btn CloseSiteMessage btn-primary btn-default" id="xxpx" onClick="setNotificationCookie();" type="submit" > <span class="lfr-btn-label">Close</span> </button> Find out more on <a href="http://www.echa.europa.eu/legal-notice#cookies">how we use cookies.</a> </p> </div> <script type="text/javascript"> // <![CDATA[ AUI().use('cookie', function(A) {(function() {var $ = AUI.$;var _ = AUI._; AUI().ready( function() { initializeCookieNotification(); initializeExplorerWarning(); } ); setNotificationCookie = function() { setCustomCookie("CookieNotification","echa_cookie","/","30"); $("#CookieNotification").slideUp(); } function initializeExplorerWarning() { var explorerOutdatedWarningDiv = A.one('.explorer-outdated-warning'); var version = getExplorerVersion(); if((version<=7) && (getCustomCookieValue("ECHAIExplorerWarning")!="suppressed")){ explorerOutdatedWarningDiv.setStyle('display','block'); } } function getExplorerVersion() { var nAgt = navigator.userAgent; var nameOffset, verOffset, version; nameOffset = nAgt.indexOf("MSIE"); if(nameOffset!=-1){ verOffset= nameOffset+5; return parseInt(nAgt.substring(verOffset).split(";")[0],10); } } function initializeCookieNotification() { var cookieNotificationDiv = A.one('#CookieNotification'); if (getCustomCookieValue("CookieNotification") !='echa_cookie'){ cookieNotificationDiv.setStyle('display', 'block'); } else{ cookieNotificationDiv.setStyle('display', 'none'); } } closeWarningMessage = function() { var toggleChecked = AUI().one("#toggleExplorerOutdatedWarningCheckbox").get('checked'); $(".explorer-outdated-warning").slideUp(); if (toggleChecked) { document.cookie="ECHAIExplorerWarning=suppressed;path=/"; } } closeTranslationMessage = function() { var toggleChecked = AUI().one("#toggleTranslationMessageCheckbox").get('checked'); $(".translation-notice").slideUp(); if (toggleChecked) { AUI().use("aui-base", "aui-io-request", function(A) { A.io.request( themeDisplay.getPathMain() + '/portal/session_attribute/set', { data: { 'disableTranslationNotice': toggleChecked }, dataType: 'JSON' } ) }); } } $(document).ready(function() { var siteMessages = A.one('#SiteMessages'); AUI().one('body').prepend(siteMessages); siteMessages.setStyle('display', 'block'); }); function initImagePanning(){ (function ($) { "use strict"; $.fn.imagePanning = function () { var $mainBanner, mainBanner, $map, $image, $mapCenterContainer, $spots, init, moveMouseEnabled, isTouch, speed, //animation/tween speed switchToMobile, autoHotspotPositionScreen, dest, lastDest, map, mapCenterContainer, $this, mapImageContainer, imgH, imgW, mapOffset, offsetTop, $this = this, mapImageContainer = this.get(0), _init = function(){ $mainBanner = $('#main-banner'); $map = $('.map'); $image = $('.map-image', $map); $mapCenterContainer = $(".map-center-container", $map); $spots = $(".js-spot"); init = "center"; moveMouseEnabled = true; isTouch = Modernizr.touchevents ? true : false; speed = isTouch ? 1000 : 1400; //animation/tween speed switchToMobile = 1200; autoHotspotPositionScreen = 479; map = $map.get(0); mainBanner = $mainBanner.get(0); mapCenterContainer = $mapCenterContainer.get(0); _update(); }, _update = function(){ imgH = $image.outerHeight(true); imgW = $image.outerWidth(true); offsetTop = $map.offset().top; mapOffset = $map.offset(); }, //custom js tween _tweenTo = function (el, prop, to, duration, easing, overwrite) { if(!el._mTween) {el._mTween = {top:{}, left:{} }; } var startTime = _getTime(), _delay, progress = 0, from = el.offsetTop, elStyle = el.style, _request, tobj = el._mTween[prop]; if(prop === "left"){ from = el.offsetLeft; } var diff = to - from; if(overwrite !== "none"){ _cancelTween(); } _startTween(); function _step() { if(!dest) return; progress = _getTime() - startTime; _tween(); if(progress >= tobj.time){ tobj.time = (progress > tobj.time) ? progress + _delay - (progress - tobj.time) : progress + _delay - 1; if(tobj.time < progress + 1){tobj.time = progress + 1; } } if(tobj.time < duration){tobj.id = _request(_step); } } function _tween() { if(duration > 0){ tobj.currVal = _ease(tobj.time,from,diff,duration,easing); elStyle[prop] = Math.round(tobj.currVal) + "px"; }else{ elStyle[prop] = to + "px"; } } function _startTween(){ _delay = 1000 / 60; tobj.time = progress + _delay; _request = (!window.requestAnimationFrame) ? function(f){_tween(); return setTimeout(f,0.01);} : window.requestAnimationFrame; tobj.id = _request(_step); } function _cancelTween() { if(tobj.id == null) { return; } if(!window.requestAnimationFrame) { clearTimeout(tobj.id); } else { window.cancelAnimationFrame(tobj.id);} tobj.id = null; } function _ease(t, b, c, d, type) { var ts = (t /= d) * t, tc = ts * t; return b + c * (0.499999999999997 * tc * ts + -2.5 * ts * ts + 5.5 * tc + -6.5 * ts + 4 * t); } function _getTime(){ if(window.performance && window.performance.now){ return window.performance.now(); }else{ if(window.performance && window.performance.webkitNow){ return window.performance.webkitNow(); }else{ if(Date.now){return Date.now(); } else {return new Date().getTime(); } } } } }, _initHotSpots = function(){ var content, direction, position, mHeight, mWidth, contentSize = {}; function setSpotContentPosition(element){ var $content, self, elOffset = {}; $content = element.find('.hot-spot-article'); if($content.length < 1) return; direction = ''; content = $content.get(0); self = element.get(0); contentSize.width = $content.width(); contentSize.height = $content.height(); mHeight = $map.height(); mWidth = $map.width(); elOffset = element.offset(); position = element.position(); if ((elOffset.top - mapOffset.top) > (mHeight / 2) ){ setVerticalDirection('toBottom'); } else{ setVerticalDirection('toTop'); } if (elOffset.left > (mWidth / 2)){ // too close to the right side of the screen on mobile if(mWidth < autoHotspotPositionScreen && position.left < contentSize.width){ setHorizontalDirection('toLeft'); }else{ setHorizontalDirection('toRight'); } }else{ // too close to the left side of the screen on mobile if(mWidth < autoHotspotPositionScreen && (imgW - mWidth) < position.left){ setHorizontalDirection('toRight'); }else{ setHorizontalDirection('toLeft'); } } if($(window).width() < autoHotspotPositionScreen){ setPosition(direction, position, elOffset, contentSize); } } function setVerticalDirection(side){ if(side === 'toTop'){ content.style.bottom = null; content.style.top = mHeight - position.top > contentSize.height + 15 ? "50%" : "-" + ( contentSize.height + 15 - (mHeight - position.top)) + 'px'; direction += 'top'; }else{ content.style.top = null; content.style.bottom = position.top > contentSize.height + 15 ? "50%" : "-" + (contentSize.height + 15 - position.top) + 'px'; direction += 'bottom'; } } function setHorizontalDirection(side){ if(side === 'toRight'){ content.style.left = null; content.style.right = "50%"; direction += '##right'; }else{ content.style.right = null; content.style.left = "50%"; direction += '##left'; } } function setPosition(direction, position, offsets, contentSize){ var contH = $map.height(), contW = $map.width(), imgH = $image.outerHeight(true), imgW = $image.outerWidth(true), x, y, moveX, moveY; if(~direction.indexOf('top')){ moveY = Math.round((imgH - contH) * (position.top / contH)) + 15; y = (moveY) < imgH - contH ? moveY : imgH - contH; }else{ moveY = Math.round((imgH - contH) * (position.top / contH)) - contentSize.height - (contH - offsets.top - $map.offset().top); y = (moveY) > 0 ? moveY : 0; } if(~direction.indexOf('left')){ x = position.left > 0 ? position.left : 0; }else{ moveX = position.left - contentSize.width ; x = moveX <= imgW - contW ? moveX : imgW - contW; } dest = [y,x]; } function setPositionAbsoluteCSS (el, x, y){ el.style.top = y+"%"; el.style.left = x+"%"; } function isNumber (n) { return !isNaN(parseFloat(n)) && isFinite(n); } $spots.each(function(i, element) { var $el = $(element), spotX, spotY; spotX = element.getAttribute('data-x'); spotY = element.getAttribute('data-y'); if((isNumber(spotX) && spotX < 100) && (isNumber(spotY) && spotY < 100)){ setPositionAbsoluteCSS(element, spotX, spotY); element.className += " visible"; $el.on("click",function(e){ var $this = $(this), $parent = $this.parent(); if($parent.hasClass('opened')) return; $parent.addClass('opened').siblings().removeClass('opened'); setSpotContentPosition($this); }); } }); }, _initCenterContainer = function(){ var topCSS = parseInt($this.css('top'),10), leftCSS = parseInt($this.css('left'),10), title = $('.map-title-container').get(0), scroller = $('.js-scroll-bottom').get(0), ww = $(document).width(); mapCenterContainer.style.top = Math.abs(topCSS) +'px'; mapCenterContainer.style.left = Math.abs(leftCSS) +'px'; mapCenterContainer.style.width = ww + 'px'; if(!title.classList.contains('visible')) title.className += ' visible'; if(!scroller.classList.contains('visible')) scroller.className += ' visible'; }, _centralize = function(){ var imgCont = $this.get(0), contH = $map.height(), contW = $map.width(); dest=[Math.round((imgH-contH)*(contH/2/contH)),Math.round((imgW-contW)*(contW/2/contW))]; imgCont.style.top = '-'+dest[0]+'px'; imgCont.style.left = '-'+dest[1]+'px'; dest = null; }, _setAspectRatio = function(windowW, windowH){ var currImgW = $image.get(0).naturalWidth, currImgH = $image.get(0).naturalHeight, ww = (windowW) ? windowW : $(window).width(), wh = (windowH) ? windowH : $(window).height(), windowRatio = ww / (wh - mapOffset.top), imageRatio = currImgW / currImgH, screenMode = (windowRatio < imageRatio) ? 'vertical' : 'horizontal', width, height; if(screenMode === 'vertical'){ height = wh - mapOffset.top, width = getImgAspectRation(currImgW, currImgH, null, height); mapImageContainer.classList.remove('vertical-fit', 'horizontal-fit'); mapImageContainer.className += ' vertical-fit'; mainBanner.style.height = height + 'px'; }else{ width = ww, height = getImgAspectRation(currImgW, currImgH, width, null); mapImageContainer.classList.remove('vertical-fit', 'horizontal-fit'); mapImageContainer.className += ' horizontal-fit'; mainBanner.style.height = wh - mapOffset.top + 'px'; } imgH = height; imgW = width; mapImageContainer.style.width = width + 'px'; mapImageContainer.style.height = height + 'px'; function getImgAspectRation(imageWidth, imageHeight, width, height){ if(width) return Math.round(width * imageHeight / imageWidth); else return Math.round(height * imageWidth / imageHeight); } }, _loadImage = function(){ //image loaded fn $image.one("load",function(){ _setAspectRatio(); setTimeout(function(){ $mainBanner.addClass("loaded"); _centralize(); },1); setTimeout(function(){ _initCenterContainer(); _initHotSpots(); moveMouseEnabled = true; },300); }).each(function(){ //run load fn even if cached if(this.complete) $(this).load(); }); }; return this.each(function(i, el){ _init(); var timer, resizeTimeout, contH, contW, imgW, imgH, $map, isPointer, evt, coords, imgCont, mapOffset = $('.map').offset().top, img = $image.get(0), touchmoved=false, mapImageCont = this, prevPage = { y: 0, x: 0 }, ww = $(window).width(), wh = $(window).height() - mapOffset; if($this.data("imagePanning")) return; this.resize = function(){ _update(); _setAspectRatio(); _centralize(); _initCenterContainer(); } _loadImage(); $this.data("imagePanning",1) //panning fn .parent().on('mousemove',function(e,p){ if(!moveMouseEnabled) return; var cont = $(this); e.preventDefault(); contH = cont.height(), contW = cont.width(), imgH = $image.outerHeight(true), imgW = $image.outerWidth(true), isTouch = e.type.indexOf("touch") !== -1, isPointer = e.type.indexOf("pointer") !== -1, evt = isPointer ? e.originalEvent : isTouch ? e.originalEvent.touches[0] || e.originalEvent.changedTouches[0] : e; moveMouseEnabled = !p ? true : false; coords=[ !p ? evt.pageY - cont.offset().top : init === "center" ? contH / 2 : 0, !p ? evt.pageX - cont.offset().left : init === "center" ? contW / 2 : 0 ]; dest = [Math.round((imgH - cont.height()) * (coords[0] / cont.height())),Math.round((imgW - cont.width()) * (coords[1] / cont.width()))]; }) .on('touchmove',function(e,p){ if(!moveMouseEnabled) return; var cont = $(this); e.preventDefault(); contH = cont.height(), contW = cont.width(), imgH = $image.outerHeight(true), imgW = $image.outerWidth(true), isTouch = e.type.indexOf("touch") !== -1, isPointer = e.type.indexOf("pointer") !== -1, evt = isPointer ? e.originalEvent : isTouch ? e.originalEvent.touches[0] || e.originalEvent.changedTouches[0] : e; moveMouseEnabled = !p ? true : false; if(!dest){ dest = [Math.round((imgH - contH) * (contH / 2 / contH)), Math.round((imgW - contW) * (contW / 2 / contW))]; } if(!touchmoved) return; var contOffset = cont.offset(), maxW = imgW-cont.width(), maxH = imgH-cont.height(), topOffset = cont.offset().top, pageX = evt.pageX - contOffset.left, pageY = evt.pageY - contOffset.top, windowW = $(window).width(), windowH = $(window).height(); if(pageX < cont.width() && pageX > 0){ // check on device touch, if(pageY < cont.height() && pageY > 0){ // if cursor is out of the frame var x = prevPage.x - pageX; var y = prevPage.y - pageY; prevPage.x = pageX; prevPage.y = pageY; dest[0] = dest[0] + y; dest[1] = dest[1] + x; if(dest[1] > 0){ if(dest[1] > maxW){ dest[1] = maxW; } }else{ dest[1] = 0; } if(dest[0] > 0){ if(dest[0] > maxH){ dest[0] = maxH; } }else{ dest[0] = 0; } } } }) .on('touchstart',function(e){ //e.preventDefault(); touchmoved = true; isTouch = e.type.indexOf("touch") !== -1, isPointer = e.type.indexOf("pointer") !== -1, evt = isPointer ? e.originalEvent : isTouch ? e.originalEvent.touches[0] || e.originalEvent.changedTouches[0] : e; prevPage.y = evt.pageY; prevPage.x = evt.pageX; }) .on('touchend',function(e){ touchmoved = false; }) $('.js-spot').on("click",function(e){ lastDest = dest; dest = null; }); $(window).on("resize",function(){ clearTimeout(resizeTimeout); resizeTimeout = setTimeout(function(){ _setAspectRatio(); _centralize(); _initCenterContainer(); $('.opened','.hotspots-list').removeClass('opened'); }, 100); }); //if(!isTouch){ //panning animation 60FPS if(timer) clearInterval(timer); timer=setInterval(function(){ if(!dest) return; _tweenTo($this[0],"top", -dest[0], speed); _tweenTo($this[0],"left", -dest[1], speed); },16.6); //} }); } $(document).ready(function(){ $('html').click(function(event) { if(!$(event.target).closest('.js-spot').length) { $('.opened','.hotspots-list').removeClass('opened'); } }); }); })(jQuery); } function initHeader(){ var $wrapper = $('#header'), $pageContent = $('.page-content'), height; if($wrapper.length < 1 || $pageContent.length < 1) return; height = $wrapper.height(); $pageContent.css('padding-top',height); var resizeTimeout; $(window).on("resize",function(){ clearTimeout(resizeTimeout); resizeTimeout = setTimeout(function(){ height = $wrapper.height(); $pageContent.css('padding-top',height); }, 100); }); } function resizeHotspotsImage(){ var $hotspotsMap = $(".map-image-container"); if($hotspotsMap.length > 0){ $hotspotsMap.get(0).resize(); } } function panHotspotsImage(){ var $hotspotsMap = $(".map-image-container"); if($hotspotsMap.length > 0){ $hotspotsMap.imagePanning(); } } function popupClose(){ setTimeout(function(){ initHeader();resizeHotspotsImage(); },425); } })();}); // ]]> </script> </div> <script type="text/javascript"> $(document).ready(function() { var textContainer = $('.showMoreLessParagraphWrapper'); textContainer.each(function(index, obj) { initializeShowHideText($(this)); }); }); function initializeShowHideText(textContainer){ var moreLink='<span id="moreLinkContainerExpanded"></span> '+ '<span id="moreLinkWrapper" class="aui-helper-hidden">'+ ' <a class="aboutMore" title="Show more" href="javascript:;"></a>'+ '</span>'; textContainer.append(moreLink); var moreLinkWrapper = textContainer.find('#moreLinkWrapper'); var limitChars=textContainer.data("limit-chars"); var limitReached = false; var totalChars = 0; var indexParagraphReached = 0; var moreLinkAdded = false; textContainer.find('p').each(function(index, obj) { if($(this).is('p')){ var pText = $.trim($(this).text().toString()); totalChars += pText.length; if(!limitReached && (totalChars > limitChars)) { limitReached = true; indexParagraphReached = index; var currentLimit = limitChars - (totalChars - pText.length); //Get the entire word, and hide the all the text after it var newLimitFullWords = pText.substring(currentLimit-1).indexOf(" ", 0); newLimitFullWords = newLimitFullWords + currentLimit; if(newLimitFullWords>currentLimit){ var part1 = pText.substring(0, newLimitFullWords); var part2 = pText.substring(newLimitFullWords); var newText = part1 + "<span id='moreLinkContainer'></span><span class='showHideText hiddenText'>" + part2 + "</span>"; $(this).html(newText); moreLinkAdded = true; } } } if(limitReached && index>indexParagraphReached){ $(this).addClass("showHideText hiddenText"); } if(limitReached && !moreLinkAdded){ $(this).append("<span id='moreLinkContainer'></span>"); moreLinkAdded = true; } }); if(limitReached){ //Add the moreLink element to the spacific paragraph var moreLinkContainer = textContainer.find("#moreLinkContainer"); moreLinkContainer.html( moreLinkWrapper.html() ); } textContainer.removeClass("aui-helper-hidden"); showHideTextOnWebContentNew(textContainer); } function showHideTextOnWebContentNew(textContainer){ var moreLinkContainer = textContainer.find("#moreLinkContainer"); var moreLinkContainerExpanded = textContainer.find("#moreLinkContainerExpanded"); textContainer.delegate("a.aboutMore", "click",function(){ var moreLink = $(this); if(!moreLink.hasClass("isTriggered")){ moreLink.addClass("isTriggered"); textContainer.find(".showHideText").removeClass("hiddenText"); moreLink.attr('rel', moreLink.attr('title')); moreLink.attr('title', ''); moreLink.appendTo(moreLinkContainerExpanded); moreLinkContainer.find('a.aboutMore').remove(); }else{ moreLink.removeClass("isTriggered"); textContainer.find(".showHideText").addClass("hiddenText"); moreLink.attr('title', moreLink.attr('rel')); moreLink.appendTo(moreLinkContainer); moreLinkContainerExpanded.find('a.aboutMore').remove(); } }); } </script> <script type="text/javascript"> // <![CDATA[ AUI().use('aui-toggler', function(A) {(function() {var $ = AUI.$;var _ = AUI._; function migratePanels(item){ console.log('migratePanels ext'); titleBar=item.one('.lfr-panel-titlebar'); panelContent=item.one('.lfr-panel-content'); if(titleBar && panelContent){ transformPanelClasses(item,titleBar,panelContent); panelContent.all('.echa-panel').each( function(item, index, collection) { titleBarNested=item.one('.lfr-panel-titlebar'); panelContentNested=item.one('.lfr-panel-content'); if(titleBarNested && panelContentNested){ transformPanelClasses(item,titleBarNested,panelContentNested); panelContentNested.html('<div class="accordion-inner">'+panelContentNested.html()+'</div>'); } }); panelContent.html('<div class="accordion-inner">'+panelContent.html()+'</div>'); } } function transformPanelClasses(item,titleBar,panelContent){ item.removeClass('lfr-collapsible'); item.removeClass('lfr-collapsed'); item.replaceClass('lfr-extended','lfr-panel-extended'); item.addClass('accordion-group'); titleBar.removeClass('lfr-panel-titlebar'); titleBar.addClass('accordion-heading'); titleBar.addClass('toggler-header'); titleBar.addClass('toggler-header-collapsed'); panelTitle=titleBar.one('.lfr-panel-title'); if(panelTitle){ panelTitle.removeClass('.lfr-panel-title') panelTitle.addClass('accordion-toggle'); spanTitle=panelTitle.one('span'); if(spanTitle){ spanTitle.addClass('title-text'); } } panelContent.removeClass('lfr-panel-content') panelContent.addClass('toggler-content'); panelContent.addClass('toggler-content-collapsed'); } AUI().ready(function(A) { var panelDivs = A.all('.echa-panel'); panelDivs.each( function(item, index, collection) { migratePanels(item); } ); }); })();}); // ]]> </script> <script type="text/javascript"> // <![CDATA[ AUI().ready(function(A) { }); // ]]> </script> <script type="text/javascript"> // <![CDATA[ AUI().use('aui-base', 'querystring-parse', function(A) {(function() {var $ = AUI.$;var _ = AUI._; AUI().ready(function(A) { var locationSearch = window.location.search; var locationSearchIndex = locationSearch.indexOf('?'); if (locationSearchIndex >= 0 && locationSearch.length > 1) { locationSearch = locationSearch.substring(locationSearchIndex + 1); var queryParams = A.QueryString.parse(locationSearch); if (queryParams.panel) { A.all('#' + queryParams.panel + '.echa-panel > .toggler-header').replaceClass('toggler-header-collapsed', 'toggler-header-expanded'); A.all('#' + queryParams.panel + '.echa-panel > .toggler-content').replaceClass('toggler-content-collapsed', 'toggler-content-expanded'); } } }); })();}); // ]]> </script> <script type="text/javascript"> // <![CDATA[ AUI().use( 'aui-base', function(A) { var frameElement = window.frameElement; if (frameElement && frameElement.getAttribute('id') === 'simulationDeviceIframe') { A.getBody().addClass('lfr-has-simulation-panel'); } } ); // ]]> </script><script type="text/javascript"> // <![CDATA[ Liferay.Loader.require('frontend-js-tooltip-support-web@2.0.5/index', function(frontendJsTooltipSupportWeb205Index) { (function(){ var TooltipSupport = frontendJsTooltipSupportWeb205Index; (function() { try { TooltipSupport.default() } catch (err) { console.error(err); } })();})(); }); // ]]> </script></body> </html>

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