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Microfluidics in IVF - Best Microfluidics Treatment | Bloom IVF

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A microfluidic device allows the oocytes to get exposed to a limited number of selected sperm. This is in contrast to microdroplet methods in static tubes or culture dishes."}},{"@type":"Question","name":"How does microfluidics in IVF work?","acceptedAnswer":{"@type":"Answer","text":"Microfluidic devices ease mixing, chemical interactions, and the processing of cells or nanoparticles. This is thus done by using precise pumps. It helps to transfer liquid through channels at different rates."}},{"@type":"Question","name":"What material makes up a microfluidic device?","acceptedAnswer":{"@type":"Answer","text":"The most popular organic polymer based on silicon, polydimethylsiloxane (PDMS), is utilized to create microfluidic devices. Because PDMS is hydrophobic, aqueous solutions are thus resisted by it."}},{"@type":"Question","name":"Which measurements are possible with microfluidics?","acceptedAnswer":{"@type":"Answer","text":"Microfluidics-based techniques are utilized to quantify cell deformation. This is thus done by employing microfluidic devices. This observes how cells react to chemical or physical stimuli. With the use of these tools, precise microenvironments can be thus created. This ensures the deliberate observation of cellular activity by fluid manipulation."}},{"@type":"Question","name":"What is microfluidics theory?","acceptedAnswer":{"@type":"Answer","text":"Microfluidics introduces small-scale fluid flow theory and practice. Liquids can be thus treated in a well-defined segmented flow fashion or a co-flow fashion. This is because of the exceptional control of such flow at low Reynolds numbers."}}]}</script> </head> <body> <!-- Header --> <div include-html="../header.html" id="fileheader"></div> <!-- breadcrumb --> <div class="page-header services-heading"> <div class="container"> <div class="row"> <div class="col-lg-12"> <h2 class="heading bold">Microfluidics in IVF</h2> </div> </div> </div> <div class="breadcrumb-wrapper"> <div class="container"> <div class="row"> <div class="col-lg-12"> <ul class="breadcrumb"> <li><a href="https://www.bloomivf.com/">Home</a></li> <li>Technical Services</li> <li class="active">Microfluidics in IVF</li> </ul> </div> </div> </div> </div> </div> <!--end breadcrumb --> <div class="container mt-80 mb-80 all-text-body"> <div class="row"> <div class="col-lg-8 col-md-8 col-sm-12 all-text-innerpages"> <img src="../assets/images/technical/microfluidics.jpg" class="img-fluid rounded mb-10" title="Microfluidics in IVF" alt="Microfluidics in IVF"> <br><br> <h1>Microfluidics in IVF: Enhancing Sperm Selection and Fertility Success</h1> <p>Reproductive medicine is evolving by the day. This is clear in the many techniques that are being used these days. There used to be a time when the mere mention of the IVF technique left people in awe. Now, the application of techniques like <strong>microfluidics in IVF</strong> has improved it further. This promises better results for couples or individuals who wish to become parents. This technique is thus used for the precise measurement and sorting of sperm. The result is that the quality of the sperm remains unhindered. Thus, this also prevents DNA breakage.</p> <p>Microfluidics technology induces the natural selection processes. These are thus carried out in a controlled setting. Why? To analyze and select the most viable sperm cells. <strong>Microfluidics in IVF</strong> help get the best results and sort sperm in the right way. This method cuts down on problems. This boosts the chances of getting pregnant by picking better sperm.</p> <h2>Understanding the Current Sperm Selection Techniques in IVF</h2> <p><a href="https://www.bloomivf.com/technical-services/icsi-treatment.html"><strong>ICSI Treatment</strong></a> is a common technique used in assisted reproductive technology (ART). This is thus used to treat male factor infertility. In this procedure, a single sperm is injected straight into an egg. The selection of superior sperm is critical to the effectiveness of ICSI. To find viable sperm, embryologists currently use some techniques. These are density gradient separation and the swim-up technique. But, these techniques are different from <strong>microfluidics in IVF</strong>.</p> <h3>Swim-Up Technique</h3> <p>The Swim-Up Technique is often employed to separate moving sperm from a semen sample. This is often done during vitro fertilization. On liquefaction, the sample is then transferred to a culture medium for each tube. This is then incubated in 45&deg; angled tubes for one hour after sperm motility. Liquefied sperm are often layered over processed non-capacitating media (top layer). This media contains the motile sperm. One may adapt the process to increase the recovery of sperm. This is often done by incorporating centrifugation either before or after swim-up. Direct Swim-Up is popular over indirect approaches. This is because it causes less oxidative damage from reactive species.</p> <h3>Density Gradient Separation</h3> <p>Density Gradient Separation is a technique used to separate sperm depending on density. Sperm are here divided into various layers based on their density in this technique. This is thus done by placing a semen sample over a material with a density gradient. Due to possible endotoxin contamination, density gradients were challenging in the initial phase. But, more recent developments have led to the introduction of density media. This is due to the usage of silane-coated silica particles. They have very low toxicity.</p> <h2>A Better Approach in Medical Science: Microfluidics Sperm Sorter Technique</h2> <p>The integration of <strong>microfluidics in IVF</strong> is a revolutionary advancement. This can help couples in fulfilling their reproductive needs. This new method can help in the proper selection and optimization of sperm. Sperm processing is getting better and better with this new technology. Microfluidic sperm sorter is a very useful tool in treating male infertility. This is especially true when conventional methods have failed. This enhances the success of ICSI and other treatments like<a href="https://www.bloomivf.com/technical-services/imsi-ivf.html"> <strong>IMSI IVF</strong></a>. Here, sperm integrity is vital for fertilization and<a href="https://www.bloomivf.com/technical-services/embryoscope.html"> <strong>Embryoscope</strong></a>.</p> <p>Microscale devices to simulate the female reproductive tract environment are a key aspect of IVF-based selection for fertilization. This involves using <strong>microfluidics in IVF</strong> sperm selection. This is to select healthy and viable sperm. Sperm that is physiologically and genetically optimal tends to move more forward. Microfluidics sperm sorter allows the healthiest, motile sperm to move efficiently. This moves through narrow fluid streams. All these take place while leaving less viable sperm and debris behind. Sperm is then deposited in a chamber for intracytoplasmic sperm injection ICSI. This is then used to fertilize the ovum.</p> <p>Teratozoospermia is a condition characterized by the absence of normal sperm or an increased DNA fragmentation index (DFI). This indicates substandard sperm quality. In the case of a failed IVF cycle, the situation can be thus resolved. This takes place even if the results of the sperm analysis appear normal. The use of microfluidics plays an important role in choosing semen with complete DNA. This ensures the best shape that prevents the use of damaged semen or unable to survive.&nbsp;</p> <p>Studies have shown that the sperm classification of microfluidics provides several benefits. This includes improving fertilization and embryo quality. This, in turn, improves pregnancy success rates after ICSI. The integration of microfluidics IVF reflects major progress in reproductive medicine. This provides new expectations and better results for couples with challenges of infertility. This increases the chances of successful fertilization. It also enhances after procedures like<a href="https://www.bloomivf.com/technical-services/timed-intercourse.html"> <strong>Timed intercourse</strong></a> and<a href="https://www.bloomivf.com/technical-services/pipelle-biopsy.html"> <strong>Pipelle Biopsy</strong></a>.</p> <h2>Bloom IVF: Equipped With the Best Microfluidics in IVF Technique</h2> <p>Bloom IVF is popular for using advanced <strong>microfluidics in IVF</strong> technology. This improves professional knowledge of sperm choices and improves IVF results. Our team of experts uses the most advanced microfluidics treatment. We simplify and improve sperm classification. This technology enables the precise manipulation and selection of high-quality sperm. This is thus based on natural behaviors such as chemotaxis, thermotaxis, and rheology. We ensure that only the best ones are chosen for fertilization. We offer customized microfluidics solutions to meet the unique needs of each patient. Our state-of-the-art microfluidic devices solve various challenges in sperm selection and embryo culture. We then personalize these systems. This, thus improves fertilization rates in an effective way and improves reproductive success. It also supports advanced techniques like<a href="https://www.bloomivf.com/technical-services/egg-donation.html"> <strong>Egg Donation</strong></a> and<a href="https://www.bloomivf.com/technical-services/hysteroscopy.html"> <strong>Hysteroscopy.</strong></a></p> <p>Bloom IVF is very committed to incorporating the latest advances in microfluidic technology. We also update our systems and technology often. By doing so, we ensure that our patients receive the highest standards of care. This dedication to innovation allows us to stay at the forefront of reproductive medicine. We are thus able to provide the most effective treatments. Bloom IVF has established itself as a leader in the use of microfluidics ivf. We have proven successful results in this field. Our patients have benefited from the clinic's professional knowledge of microfluidics in IVF. We also have the highest results achieved through advanced microfluidic technology.</p> <p> <strong>If you are looking for the best microfluidics in IVF consultation or treatment, Bloom IVF is the best option.</strong></p> </div> <div class="col-lg-4 mt-40 mt-lg-0"> <!-- Technical Right --> <div include-html="../include/technical-right-box.html" id="TechnicalRight"></div> <!--end Technical Right--> </div> </div> </div> <section class="step-boxmain"> <div class="container-fluid"> <div class="row justify-content-center"> <div class="col-lg-11"> <div style="text-align: center; margin-bottom:50px;"> <h3 class="heading text-lh-4" style="font-weight: 600;">Step-by-Step Procedure of Microfluidics</h3> <!-- <p class="sub-heading">Lorem Ipsum is simply dummy text of the printing and typesetting industry.</p> --> </div> </div> </div> <div class="row no-gutters stepheding justify-content-center"> <div class="col-lg-2 mt-20"> <div class="process-box-1 first"> <div class="process-box-header"> <!-- <i class="ion-layers-outline icon"></i> --> <span class="strokeme">1</span> </div> <div class="process-box-body"> <h5 class="heading font-bold">Check collected semen for viscosity, volume, count and motility.</h5> </div> </div> </div> <div class="col-lg-2 mt-20"> <div class="process-box-1"> <div class="process-box-header"> <span class="strokeme">2</span> </div> <div class="process-box-body"> <h5 class="heading font-bold">Sample with normal viscosity, volume more than 0.8 ml can be selected for MF</h5> </div> </div> </div> <div class="col-lg-2 mt-20"> <div class="process-box-1"> <div class="process-box-header"> <span class="strokeme">3</span> </div> <div class="process-box-body"> <h5 class="heading font-bold">Selected sample is injected through the inlet port of the MF chamber.</h5> </div> </div> </div> <div class="col-lg-2 mt-20"> <div class="process-box-1"> <div class="process-box-header"> <span class="strokeme">4</span> <!-- <i class="ion-layers-outline icon"></i> --> </div> <div class="process-box-body"> <h5 class="heading font-bold">Incubate the chamber for 20-30 mins</h5> </div> </div> </div> <div class="col-lg-2 mt-20"> <div class="process-box-1"> <div class="process-box-header"> <!-- <i class="ion-layers-outline icon"></i> --> <span class="strokeme">5</span> </div> <div class="process-box-body"> <h5 class="heading font-bold">Post wash sample is collected through the outlet port.</h5> </div> </div> </div> </div> </div> </section> <!-- treatment recommended --> <!--section> <div class="providing-box"> <div class="container p-0"> <div class="row no-gutters align-items-center"> <div class="col-lg-3"> </div> <div class="col-lg-9 pl-80 mt-20 wow fadeInRight recommended-box" data-wow-delay="0.3s" style="visibility: visible; animation-delay: 0.3s; animation-name: fadeInRight;"> <h3>Simply dummy text treatment recommended?</h3> <p>Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.</p> <p>There are many variations of passages of Lorem Ipsum available, but the majority have suffered alteration in some form, by injected humour, or randomised words which don't look even slightly believable. If you are going to use a passage of Lorem Ipsum, you need to be sure there isn't anything embarrassing hidden in the middle of text. </p> </div> </div> </div> </div> </section--> <!-- end treatment recommended --> <!-- Questions --> <section style="background-color: #fff; padding:80px 0px;"> <div class="container"> <div class="row justify-content-center"> <div class="col-lg-8"> <div class="heading-block"> <h3 class="heading text-lh-4">Common Questions</h3> <p class="sub-heading">If you could not find an answer to your query, please contact us. </p> </div> </div> </div> <div class="row"> <div class="col-lg-6 mt-20"> <div id="a3" class="accordion-3" role="tablist"> <div class="accordion-item"> <div class="accordion-heading" role="tab" id="a3heading1"> <h6 class="accordion-title font-bold"> <a class="collapsed" role="button" data-toggle="collapse" href="#a3body1" aria-expanded="true" aria-controls="a3body1"> What are microfluidics? </a> </h6> </div> <div id="a3body1" data-parent="#a3" class="accordion-body collapse" role="tabpanel" aria-labelledby="a3heading1"> <div class="accordion-data"> Microfluidics is a multidisciplinary field that examines the behaviour of fluids in micro-sized channels and devices and applies that knowledge to the creation of new technologies. </div> </div> </div> <div class="accordion-item"> <div class="accordion-heading" role="tab" id="a3heading2"> <h6 class="accordion-title font-bold"> <a class="collapsed" role="button" data-toggle="collapse" href="#a3body2" aria-expanded="false" aria-controls="a3body2"> What exactly is microfluidic technology in IVF? </a> </h6> </div> <div id="a3body2" data-parent="#a3" class="accordion-body collapse" role="tabpanel" aria-labelledby="a3heading2"> <div class="accordion-data"> The main benefit of the microfluidic-based IVF chip over traditional methods is its ability to lower the risk of polyspermy. A microfluidic device allows the oocytes to get exposed to a limited number of selected sperm. This is in contrast to microdroplet methods in static tubes or culture dishes. </div> </div> </div> <div class="accordion-item"> <div class="accordion-heading" role="tab" id="a3heading3"> <h6 class="accordion-title font-bold"> <a class="collapsed" role="button" data-toggle="collapse" href="#a3body3" aria-expanded="false" aria-controls="a3body3"> How does microfluidics in IVF work?</a> </h6> </div> <div id="a3body3" class="accordion-body collapse" data-parent="#a3" role="tabpanel" aria-labelledby="a3heading3"> <div class="accordion-data"> Microfluidic devices ease mixing, chemical interactions, and the processing of cells or nanoparticles. This is thus done by using precise pumps. It helps to transfer liquid through channels at different rates. </div> </div> </div> </div> </div> <div class="col-lg-6 mt-20"> <div id="a2" class="accordion-3" role="tablist"> <div class="accordion-item"> <div class="accordion-heading" role="tab" id="a2heading1"> <h6 class="accordion-title font-bold"> <a class="collapsed" role="button" data-toggle="collapse" href="#a2body1" aria-expanded="true" aria-controls="a2body1"> What material makes up a microfluidic device? </a> </h6> </div> <div id="a2body1" data-parent="#a2" class="accordion-body collapse" role="tabpanel" aria-labelledby="a2heading1"> <div class="accordion-data"> The most popular organic polymer based on silicon, polydimethylsiloxane (PDMS), is utilized to create microfluidic devices. Because PDMS is hydrophobic, aqueous solutions are thus resisted by it. </div> </div> </div> <div class="accordion-item"> <div class="accordion-heading" role="tab" id="a2heading2"> <h6 class="accordion-title font-bold"> <a class="collapsed" role="button" data-toggle="collapse" href="#a2body2" aria-expanded="false" aria-controls="a2body2"> Which measurements are possible with microfluidics? </a> </h6> </div> <div id="a2body2" data-parent="#a2" class="accordion-body collapse" role="tabpanel" aria-labelledby="a2heading2"> <div class="accordion-data"> Microfluidics-based techniques are utilized to quantify cell deformation. This is thus done by employing microfluidic devices. This observes how cells react to chemical or physical stimuli. With the use of these tools, precise microenvironments can be thus created. This ensures the deliberate observation of cellular activity by fluid manipulation. </div> </div> </div> <div class="accordion-item"> <div class="accordion-heading" role="tab" id="a2heading3"> <h6 class="accordion-title font-bold"> <a class="collapsed" role="button" data-toggle="collapse" href="#a2body3" aria-expanded="false" aria-controls="a2body3"> What is microfluidics theory?</a> </h6> </div> <div id="a2body3" class="accordion-body collapse" data-parent="#a2" role="tabpanel" aria-labelledby="a2heading3"> <div class="accordion-data"> Microfluidics introduces small-scale fluid flow theory and practice. Liquids can be thus treated in a well-defined segmented flow fashion or a co-flow fashion. This is because of the exceptional control of such flow at low Reynolds numbers. </div> </div> </div> </div> </div> </div> <div class="row mt-50"> <div class="col-lg-12 text-center"> <!--<p class="mb-20">If you could not find an answer to your query, please contact us.</p>--> <a href="../contact-us.html" class="btn btn-primary">Raise a Query</a> </div> </div> </div> </section> <!--end Questions --> <!--Popular Searches microfluidics in IVF--> <section class="searches-box-list"> <div class="container"> <div class="row"> <h3>Popular Searches</h3> <ul> <li><a href="https://www.bloomivf.com/dr-nandita-palshetkar.html">IVF Doctor</a></li> <li> <a href="https://www.bloomivf.com/technical-services/lapaparoscopic-surgery.html">Laparoscopic Surgery Cost</a></li> <li> <a href="https://www.bloomivf.com/technical-services/ivf-treatment.html">IVF Treatment Cost</a></li> <li> <a href="https://www.bloomivf.com/technical-services/iui-treatment.html">IUI Treatment Cost</a></li> <li> <a 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