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How Does Auxin Turn On Genes? | Plant Physiology | Oxford Academic

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</div> </div> <div class="info-card-affilitation"> <div class="aff"><span class="label title-label"><sup>1</sup></span>Department of Biochemistry, 117 Schweitzer Hall, Columbia, Missouri 65211</div> </div> <div class="info-card-search-label"> Search for other works by this author on: </div> <div class="info-card-search info-card-search-internal"> <a href="/plphys/search-results?f_Authors=Tom+Guilfoyle" rel="nofollow">Oxford Academic</a> </div> <div class="info-card-search info-card-search-google"> <a href="http://scholar.google.com/scholar?q=author:%22Guilfoyle Tom%22">Google Scholar</a> </div> </div> </span> </span> <span class="al-author-name-more js-flyout-wrap"> <button type="button" class="linked-name js-linked-name-trigger btn-as-link">Gretchen Hagen</button><span class='delimiter'>, </span> <span class="al-author-info-wrap arrow-up"> <div class="info-card-author authorInfo_OUP_Abstract_ArticleTop_Info_Widget"> <div class="name-role-wrap"> <div class="info-card-name"> Gretchen 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class="icon-menu_search js_expand-navsearch"><span class="screenreader-text">Search Menu</span></a></div> </div> </div> <input id="routename" name="RouteName" type="hidden" value="plphys" /> </div> </div> </div> </div> <div id="ContentTab" class="content active"> <div class="widget widget-ArticleFulltext widget-instance-OUP_Abstract_Article_FullText_Widget"> <div class="module-widget"> <div class="widget-items" data-widgetname="ArticleFulltext"> <h2 class="abstract-title js-splitscreen-abstract-title at-Extract-Title">Extract</h2> <section class="abstract extract"> <p class="chapter-para">The plant hormone auxin (or IAA) plays a key role in a wide variety of growth and developmental processes. At the cellular level, auxin acts as a signal for division, extension, and differentiation during the course of the plant life cycle. At the whole-plant level, auxin plays an important role in root formation, apical dominance, tropism, and senescence. The question is how does such a simple molecule regulate such a plethora of responses within an assortment of cells, tissues, and organs of plants?</p><p class="chapter-para">The answer to this question requires an understanding of auxin perception, signal transduction, and gene regulation. At this time, little is known about how auxin is recognized as a hormone by plant cells or what receptor molecules are involved in this recognition. Although several classes of auxin-binding proteins have been identified and characterized (for review, see <span class="xrefLink" id="jumplink-R17"></span>Napier and Venis, 1995), it is not clear which if any of these function as receptors in signal transduction pathways that target the nucleus and regulate auxin-responsive gene expression. Likewise, the auxin signal transduction pathway involved in early auxin-regulated gene expression is currently a mystery. It is possible that one or several classes of auxin receptors and auxin signal transduction pathways exist in plant cells, and that these receptors and pathways are not uniformly distributed among different cell types and tissues. 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