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masthead--image alignfull" aria-label="Banner">  <div class="masthead__media"> <picture> <img src='https://www.ppd.com/wp-content/uploads/2021/10/neurodegenerative-disease-header-shutterstock_1197120001-1200x600.jpg' width='1200' height='600' srcset='' alt='Neurodegenerative Diseases Expertise' class='object-pos-center' /> </picture> </div> <div class="masthead__overlay"> </div>  <div class="masthead__content-wrapper alignwide"> <div class="masthead__content"> <h1 class="masthead__title">Neurodegenerative Disease Research Expertise</h1> </div> </div> </section> <div class="breadcrumbs alignfull"><div class="breadcrumbs__inner"><div class="breadcrumbs__wrapper"><div class="breadcrumbs"><span><span><a href="https://www.ppd.com/therapeutic-expertise/">Therapeutic Expertise</a></span> <span class="breadcrumb-separator"></span> <span><a href="https://www.ppd.com/therapeutic-expertise/neuroscience-clinical-research/">Neuroscience Research</a></span> <span class="breadcrumb-separator"></span> <span class="breadcrumb_last" aria-current="page">Neurodegenerative Disorders</span></span></div></div></div></div> <div class="wp-block-emagine-columns alignfull"><div id="em-layout-id_62b13d-99" class="em-row-layout-inner em-margin-top--default em-margin-bottom--default em-tablet-margin-top--default em-tablet-margin-bottom--default em-mobile-margin-top--default em-mobile-margin-bottom--default em-layout-id_62b13d-99"><div class="em-row-column-wrap em-has-2-columns em-gutter-default em-row-valign-top em-row-layout-left-golden em-tab-layout-left-golden em-m-colapse-left-to-right em-mobile-layout-row em-padding-top--default em-padding-bottom--default em-tablet-padding-top--default em-tablet-padding-bottom--default em-mobile-padding-top--default em-mobile-padding-bottom--default alignwide"> <div class="wp-block-emagine-column emagine-column4294 inner-column-1"><div class="em-inside-inner-col em-padding-top--none em-padding-right--none em-padding-bottom--none em-padding-left--none em-tablet-padding-top--none em-tablet-padding-right--medium em-tablet-padding-bottom--none em-tablet-padding-left--none em-mobile-padding-top--none em-mobile-padding-right--none em-mobile-padding-bottom--medium em-mobile-padding-left--none"> <h2 class="wp-block-heading">Experience with neurodegenerative indication research studies</h2> <p>Global rates of neurodegenerative diseases — including Parkinson’s disease and dementias like Alzheimer’s disease —are increasing, and a significant gap remains between the clinical need for neurodegenerative treatments and the options available to patients and their caregivers.</p> <p>To chart the best path forward for neurodegenerative disorder therapies, drug developers require partnership with a research team that has the operational and medical knowledge across indications and can leverage novel approaches, such as decentralized trials and clinical trial simulations.</p> <div style="height:1rem" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-emagine-button"><a class="wp-block-emagine-button__more has-purple-background-color block-btn block-btn--sm block-btn--primary" style="background-color:#633a97" href="#contact-us" rel=""><span class="block-btn__hover" style="color:#fff;background-color:#4f2683;border-color:transparent">Connect with our neurodegenerative disease experts</span></a></div> <p class="mb-0">In the past five years, the PPD™ clinical research business of Thermo Fisher Scientific has performed <strong>more than 50 studies</strong> across a range of rare neuroscientific indications. This includes studies pursuing treatments for neurodegenerative diseases, including:</p> <ul class="wp-block-list"> <li>Alzheimer’s disease (disease modifying and symptomatic)</li> <li>Dementia with Lewy bodies</li> <li>Frontotemporal lobe dementia</li> <li>Gene therapy</li> <li>Parkinson’s disease</li> <li>Radiopharmaceutical</li> <li>Single-ascending-dose (SAD) and multiple-ascending dose (MAD) trials</li> </ul> </div></div> <div class="wp-block-emagine-column emagine-column2450 inner-column-2"><div class="em-inside-inner-col em-padding-top--none em-padding-right--none em-padding-bottom--none em-padding-left--none em-tablet-padding-top--none em-tablet-padding-right--none em-tablet-padding-bottom--none em-tablet-padding-left--none em-mobile-padding-top--none em-mobile-padding-right--none em-mobile-padding-bottom--none em-mobile-padding-left--none"><section id="anchor-link-menu-block_6bd3a8d13438e218aae2a33cc2754d78" class="anchor-link-menu alignfull"> <div class="anchor-link-menu__title"> On this page </div> <div class="anchor-link-menu__links"> <ul> <li><a href="#sites">Sites and Patients Access</a></li> <li><a href="#robust">Robust Patient Access Solutions</a></li> </ul> </div> </section> <div style="height:1.5rem" aria-hidden="true" class="wp-block-spacer"></div> <a href="/therapeutic-expertise/neuroscience-clinical-research/neurodegenerative-diseases/alzheimer-patient-caregiver-survey/" target="" id="ppd-card-block_d813760f22a6a95a255728e75b0b02a6" class="ppd-card alignfull fit-content "> <div class="ppd-card__image"> <img decoding="async" src="https://www.ppd.com/wp-content/uploads/2023/06/Assessing-Caregiver-Burden-for-Alzheimers-Patients_Thumbnail-627x440.png" alt="PPD Summary of 2022 Survey: Caregiver burden for Alzheimer's patients"> </div> <div class="ppd-card__inner"> <div class="ppd-card__top"> <div class="ppd-card__title">Assessing caregiver burden for Alzheimer’s patients</div> <p class="ppd-card__content">Explore findings from a survey of Alzheimer’s disease caregivers assessing clinical trial participation.</p> </div> <div class="ppd-card__bottom"> <span class="ppd-card__link" >Read the summary</span> </div> </div> </a> </div></div> </div></div></div> <section id="sites" class="media-content alignfull has-bg-image dark-text thirds-layout align-content-center " style=""> <div class="alignwide align-bg"> <div class="media-content__image bg-image" style="background-image: url(https://www.ppd.com/wp-content/uploads/2021/10/neurodegenerative-disease-site-patient-shutterstock_1668010567-616975b1d6ef9.jpg);"></div> <div class="media-content__content has-container right-content"> <div class="content-container"> <h2 class="media-content__title2">Solutions for neurodegenerative clinical trial sites and patient access</h2> <div class="media-content__desc"><p>Gaining unique access to indication-specific sites for neurodegenerative clinical trials and a worldwide site network is critical to driving your therapy forward. Access to sites and site networks is just the beginning. These sites must prioritize ongoing support and training of health care professionals in the clinical trials space to ensure the delivery of industry-leading speed, skill, efficiency and quality benchmarks across neurodegenerative trials for all indications. By partnering with us, you’ll have access to the site and training services you need, including:</p> <p>Site and training services include:</p> <ul> <li>Our wholly-owned clinical research unit in Orlando, Florida, which has extensive experience in neurodegenerative disorders, <a href="/our-solutions/clinical/early-phase-clinical-trials/">early development</a> and SAD/MAD research</li> <li><a href="/our-solutions/clinical/site-patient-centric-solutions/sitecoach/">SiteCoach</a>, our training program to support health care practitioners at sites new to clinical research</li> </ul> </div> </div> </div> </div> </section> <section id="robust" class="media-content alignfull has-bg-image dark-text thirds-layout invert-mobile align-content-center " style=""> <div class="alignwide align-bg"> <div class="media-content__content has-container left-content"> <div class="content-container"> <h2 class="media-content__title2">Robust patient access solutions drive neurodegenerative disorder trial success</h2> <div class="media-content__desc"><p>Success in neurodegenerative disorder trials depends on patient and caregiver participation. To reduce the individual burden for patients and their caregivers — and ensure patient enrollment and retention — drug developers should partner with a contract research organiztion (CRO) that provides extensive patient support services.</p> <p>Our extensive patient support service offerings include:</p> <ul> <li>Enhanced diversity and collaboration with patient advocacy groups <ul> <li>Helps ensure enrollment aligns with real-world disease incidence and regulatory guidance</li> </ul> </li> <li>Increased access through minimized patient burden <ul> <li>Home health care options, including partnering with remote staff</li> <li><a href="https://www.ppd.com/how-we-help/decentralized-clinical-trials/">Digital and hybrid clinical trial solutions</a> and protocols leveraging mobile pages, wearables, telehealth and e-consent</li> <li>Proactive patient concierge services that offer reliable patient transportation and travel expense verification</li> <li>Flexible options for patient reimbursement in more than 150 currencies</li> </ul> </li> </ul> </div> </div> </div> <div class="media-content__image bg-image" style="background-image: url(https://www.ppd.com/wp-content/uploads/2021/10/neuroscience-shutterstock_1562123101.jpg);"></div> </div> </section> <section id="media-content-block_77a6bd6ac51a6a7a60eac03c68ffbf30" class="media-content alignfull has-bg-image thirds-layout align-content-center " style=""> <div class="alignwide align-bg"> <div class="media-content__image bg-image" style="background-image: url(https://www.ppd.com/wp-content/uploads/2023/04/data-visualization-3d-shutterstock_601064474.jpg);"></div> <div class="media-content__content has-container right-content"> <div class="content-container"> <h2 class="media-content__title2">Clinical trial design for Alzheimer’s disease research with ACE Simulator </h2> <div class="media-content__desc"><p>Our scientists designed the <a href="https://www.evidera.com/ace/" target="_blank" rel="noopener">Archimedes condition-event (ACE) simulator</a> by building on widely used models for treating Alzheimer’s disease. The ACE simulator assesses interventions from the earliest stages (i.e., mild cognitive impairment or prodromal Alzheimer’s disease) through the most severe stages of the neurodegenerative disease, mapping the transition from normal cognitive function and helping optimize trial design.</p> </div> </div> </div> </div> </section> <div class="wp-block-emagine-columns alignfull"><div id="em-layout-id_7e557b-38" class="em-row-layout-inner em-margin-top--default em-margin-bottom--default em-tablet-margin-top--default em-tablet-margin-bottom--default em-mobile-margin-top--none em-mobile-margin-bottom--default em-layout-id_7e557b-38"><div class="em-row-column-wrap em-has-1-columns em-gutter-default em-row-valign-top em-row-layout-equal em-tab-layout-inherit em-m-colapse-left-to-right em-mobile-layout-row em-padding-top--default em-padding-bottom--default em-tablet-padding-top--default em-tablet-padding-bottom--default em-mobile-padding-top--none em-mobile-padding-bottom--default alignwide"> <div class="wp-block-emagine-column emagine-column7768 inner-column-1"><div class="em-inside-inner-col em-padding-top--none em-padding-right--none em-padding-bottom--none em-padding-left--none em-tablet-padding-top--none em-tablet-padding-right--none em-tablet-padding-bottom--none em-tablet-padding-left--none em-mobile-padding-top--none em-mobile-padding-right--none em-mobile-padding-bottom--none em-mobile-padding-left--none"> <h3 class="wp-block-heading has-text-align-center" style="text-transform:none">Additional neurodegenerative disease resources</h3> <div class="wp-block-emagine-columns alignfull"><div id="em-layout-id_73a244-0a" class="em-row-layout-inner em-margin-top--default em-margin-bottom--none em-tablet-margin-top--none em-tablet-margin-bottom--none em-mobile-margin-top--none em-mobile-margin-bottom--none em-layout-id_73a244-0a"><div class="em-row-column-wrap em-has-3-columns em-gutter-default em-row-valign-top em-row-layout-equal em-tab-layout-inherit em-m-colapse-left-to-right em-mobile-layout-row em-padding-top--none em-padding-bottom--none em-tablet-padding-top--default em-tablet-padding-bottom--none em-mobile-padding-top--none em-mobile-padding-bottom--none alignfull"> <div class="wp-block-emagine-column emagine-column5435 inner-column-1"><div class="em-inside-inner-col em-padding-top--none em-padding-right--none em-padding-bottom--none em-padding-left--none em-tablet-padding-top--none em-tablet-padding-right--none em-tablet-padding-bottom--none em-tablet-padding-left--none em-mobile-padding-top--none em-mobile-padding-right--none em-mobile-padding-bottom--none em-mobile-padding-left--none"><a href="https://www.ppd.com/therapeutic-expertise/neuroscience-clinical-research/neurodegenerative-diseases/reducing-caregiver-burden-webinar/" target="" id="ppd-card-block_e02b879e2d79bf0f3e6f3929d54892e3" class="ppd-card alignfull "> <div class="ppd-card__image"> <img decoding="async" src="https://www.ppd.com/wp-content/uploads/2023/06/reducing-caregiver-burden-in-alzheimers-disease-clinical-trials-to-boost-patient-recruitment-webinar-760x440.jpg" alt="PPD and XTalks Webinar: Reducing caregiver burden in Alzheimer's disease clinical trials to boost patient recruitment."> </div> <div class="ppd-card__inner"> <div class="ppd-card__top"> <div class="ppd-card__title">Reducing caregiver burden in Alzheimer’s disease clinical trials</div> <p class="ppd-card__content">It is critical that early program design includes strategies to address the caregiver needs to reduce participant burden.</p> </div> <div class="ppd-card__bottom"> <span class="ppd-card__link" >Watch and learn why</span> </div> </div> </a> </div></div> <div class="wp-block-emagine-column emagine-column3902 inner-column-2"><div class="em-inside-inner-col em-padding-top--none em-padding-right--none em-padding-bottom--none em-padding-left--none em-tablet-padding-top--none em-tablet-padding-right--none em-tablet-padding-bottom--none em-tablet-padding-left--none em-mobile-padding-top--none em-mobile-padding-right--none em-mobile-padding-bottom--none em-mobile-padding-left--none"><a href="https://www.ppd.com/therapeutic-expertise/neuroscience-clinical-research/neurodegenerative-diseases/recruiting-parkinsons-trials/" target="" id="ppd-card-block_23d42092e6e5cc9e8f5a6d472bad2572" class="ppd-card alignfull "> <div class="ppd-card__image"> <img decoding="async" src="https://www.ppd.com/wp-content/uploads/2024/04/Recruiting-Parkinsons-Disease-Patients_thumbnail-min-756x440.jpg" alt="Recruiting Parkinson’s Disease Patients for Clinical Trials PDF"> </div> <div class="ppd-card__inner"> <div class="ppd-card__top"> <div class="ppd-card__title">Recruiting Parkinson’s disease patients for clinical trials</div> <p class="ppd-card__content">Addressing the challenges of populating Parkinson’s disease clinical research studies starts with knowing the patient.</p> </div> <div class="ppd-card__bottom"> <span class="ppd-card__link" >Read the white paper</span> </div> </div> </a> </div></div> <div class="wp-block-emagine-column emagine-column5925 inner-column-3"><div class="em-inside-inner-col em-padding-top--none em-padding-right--none em-padding-bottom--none em-padding-left--none em-tablet-padding-top--none em-tablet-padding-right--none em-tablet-padding-bottom--none em-tablet-padding-left--none em-mobile-padding-top--none em-mobile-padding-right--none em-mobile-padding-bottom--none em-mobile-padding-left--none"><a href="/therapeutic-expertise/neuroscience-clinical-research/growth-in-neurodegenerative-opportunities/" target="" id="ppd-card-block_0415b8534183a5ac36b838e8befec4ec" class="ppd-card alignfull "> <div class="ppd-card__image"> <img decoding="async" src="https://www.ppd.com/wp-content/uploads/2022/10/PPD271_Neurodegenerative-Treatment-Opportunities-536x440.png" alt="PPD271_Neurodegenerative-Treatment-Opportunities article cover"> </div> <div class="ppd-card__inner"> <div class="ppd-card__top"> <div class="ppd-card__title">Preparing for growth in neurodegenerative disease research and treatment opportunities</div> <p class="ppd-card__content">Growth in neurodegenerative treatment and how we support these clinical trials.</p> </div> <div class="ppd-card__bottom"> <span class="ppd-card__link" >Read the article</span> </div> </div> </a> </div></div> </div></div></div> </div></div> </div></div></div> <div class="wp-block-emagine-columns alignfull" id="contact-us"><div id="em-layout-id_290231-e5" class="em-row-layout-inner em-margin-top--none em-margin-bottom--none em-tablet-margin-top--none em-tablet-margin-bottom--none em-mobile-margin-top--none em-mobile-margin-bottom--none em-row-has-bg em-layout-id_290231-e5"><div class="em-row-column-wrap em-has-1-columns em-gutter-default em-row-valign-top em-row-layout-equal em-tab-layout-inherit em-m-colapse-left-to-right em-mobile-layout-row em-padding-top--xlarge 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