CINXE.COM

<!DOCTYPE html> <html lang="en" dir="ltr"> <head>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-P63WKM1TM1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-P63WKM1TM1'); </script>  <script type="text/javascript" > (function(m,e,t,r,i,k,a){m[i]=m[i]||function(){(m[i].a=m[i].a||[]).push(arguments)}; m[i].l=1*new Date(); for (var j = 0; j < document.scripts.length; j++) {if (document.scripts[j].src === r) { return; }} k=e.createElement(t),a=e.getElementsByTagName(t)[0],k.async=1,k.src=r,a.parentNode.insertBefore(k,a)}) (window, document, "script", "https://mc.yandex.ru/metrika/tag.js", "ym"); ym(55165297, "init", { clickmap:false, trackLinks:true, accurateTrackBounce:true, webvisor:false }); </script> <noscript><div><img src="https://mc.yandex.ru/watch/55165297" style="position:absolute; left:-9999px;" alt="" /></div></noscript>    <title>Search results for: hydroxyapatite</title> <meta name="description" content="Search results for: hydroxyapatite"> <meta name="keywords" content="hydroxyapatite"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="hydroxyapatite" name="q" aria-label="Search"> <button class="btn btn-light my-2 my-sm-0" type="submit"><i class="fas fa-search"></i></button> </form> </div> <div class="collapse navbar-collapse mt-1" id="navbarMenu"> <ul class="navbar-nav ml-auto align-items-center" id="mainNavMenu"> <li class="nav-item"> <a class="nav-link" href="https://waset.org/conferences" title="Conferences in 2024/2025/2026">Conferences</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/disciplines" title="Disciplines">Disciplines</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/committees" rel="nofollow">Committees</a> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdownPublications" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"> Publications </a> <div class="dropdown-menu" aria-labelledby="navbarDropdownPublications"> <a class="dropdown-item" href="https://publications.waset.org/abstracts">Abstracts</a> <a class="dropdown-item" href="https://publications.waset.org">Periodicals</a> <a class="dropdown-item" href="https://publications.waset.org/archive">Archive</a> </div> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/page/support" title="Support">Support</a> </li> </ul> </div> </div> </nav> </div> </header> <main> <div class="container mt-4"> <div class="row"> <div class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="hydroxyapatite"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 113</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: hydroxyapatite</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">113</span> Fabrication of Wollastonite/Hydroxyapatite Coatings on Zirconia by Room Temperature Spray Process</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jong%20Kook%20Lee">Jong Kook Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Sangcheol%20Eum"> Sangcheol Eum</a>, <a href="https://publications.waset.org/abstracts/search?q=Jaehong%20Kim"> Jaehong Kim </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Wollastonite/hydroxyapatite composite coatings on zirconia were obtained by room temperature spray process. Wollastonite powder was synthesized by solid-state reaction between calcite and silica powder. Hydroxyapatite powder was prepared from bovine bone by the calcination at 1200oC 1h. From two starting raw powders, three kinds of powder mixture were obtained by the ball milling for 24h. By using these powders, wollastonite/hydroxyapatite coatings were fabricated on zirconia substrates by a room temperature spray process, and their microstructure and biological behavior were investigated and compared with pure wollastonite and hydroxyapatite coatings. Wollastonite/hydroxyapatite coatings on zirconia substrates were homogeneously formed in microstructure and had a nanoscaled grain size. The phase composition of the resultant wollastonite/hydroxyapatite coatings was similar to that of the starting powders, however, the grain size of the wollastonite or hydroxyapatite particles was reduced to about 100 nm due to their formation by particle impaction and fracture. The wollastonite/hydroxyapatite coating layer exhibited bioactivity in a stimulated body fluid and forming ability of new hydroxyapatite precipitates of 25 nm during in vitro test in SBF solution, which was enhanced by the increasing wollastonite content. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=wollastonite" title="wollastonite">wollastonite</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite%20%20composite%20coatings" title=" hydroxyapatite composite coatings"> hydroxyapatite composite coatings</a>, <a href="https://publications.waset.org/abstracts/search?q=room%20temperature%20spay%20process" title=" room temperature spay process"> room temperature spay process</a>, <a href="https://publications.waset.org/abstracts/search?q=zirconia" title=" zirconia "> zirconia </a> </p> <a href="https://publications.waset.org/abstracts/25551/fabrication-of-wollastonitehydroxyapatite-coatings-on-zirconia-by-room-temperature-spray-process" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25551.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">476</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">112</span> Preparation, Characterization, and in-Vitro Drug Release Study of Methotrexate-Loaded Hydroxyapatite-Sodium Alginate Nanocomposites</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Friday%20G.%20Okibe">Friday G. Okibe</a>, <a href="https://publications.waset.org/abstracts/search?q=Edit%20B.%20Agbaji"> Edit B. Agbaji</a>, <a href="https://publications.waset.org/abstracts/search?q=Victor%20O.%20Ajibola"> Victor O. Ajibola</a>, <a href="https://publications.waset.org/abstracts/search?q=Christain%20C.%20Onoyima"> Christain C. Onoyima</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Controlled drug delivery systems reduce dose-dependent toxicity associated with potent drugs, including anticancer drugs. In this research, hydroxyapatite (HA) and hydroxyapatite-sodium alginate nanocomposites (HASA) were successfully prepared and characterized using Fourier Transform Infrared spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The FTIR result showed absorption peaks characteristics of pure hydroxyapatite (HA), and also confirmed the chemical interaction between hydroxyapatite and sodium alginate in the formation of the composite. Image analysis from SEM revealed nano-sized hydroxyapatite and hydroxyapatite-sodium alginate nanocomposites with irregular morphologies. Particle size increased with the formation of the nanocomposites relative to pure hydroxyapatite, with no significant change in particles morphologies. Drug loading and in-vitro drug release study were carried out using synthetic body fluid as the release medium, at pH 7.4 and 37 °C and under perfect sink conditions. The result shows that drug loading is highest for pure hydroxyapatite and decreased with increasing quantity of sodium alginate. However, the release study revealed that HASA-5%wt and HASA-20%wt presented better release profile than pure hydroxyapatite, while HASA-33%wt and HASA-50%wt have poor release profiles. This shows that Methotrexate-loaded hydroxyapatite-sodium alginate if prepared under optimal conditions is a potential carrier for effective delivery of Methotrexate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=drug-delivery" title="drug-delivery">drug-delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=methotrexate" title=" methotrexate"> methotrexate</a>, <a href="https://publications.waset.org/abstracts/search?q=nanocomposites" title=" nanocomposites"> nanocomposites</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20alginate" title=" sodium alginate"> sodium alginate</a> </p> <a href="https://publications.waset.org/abstracts/53235/preparation-characterization-and-in-vitro-drug-release-study-of-methotrexate-loaded-hydroxyapatite-sodium-alginate-nanocomposites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/53235.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">277</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">111</span> Percentages of Alumina Phase and Different Ph on The Ha- Al2o3 Nano Composite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Tayyebi">S. Tayyebi</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Mirjalili"> F. Mirjalili</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Samadi"> H. Samadi</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Nemati"> A. Nemati</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, hydroxyapatite-Alumina nano composite powder, containing 15,20 and 25% weight percent of reinforced alumina were prepared by chemical precipitation from the reaction between calcium nitrate tetrahydrate and di-ammonium hydrogen phosphate with ratio of Ca / p = 1.67 and different percentage of aluminum nitrate nona hydrate in different pH of 9,10 and 11. The microstructure and thermal stability of samples were measured by X-ray diffraction (XRD), infrared spectroscopy (FT-IR) and transmission electron microscopy (TEM). The results showed that the presence of reinforced alumina phase reduced the degree of crystallinity of hydroxyapatite phase and increased its decomposition to tricalcium phosphate phase. Microstructural analysis showed that the hydroxyapatite-alumina nano composite powder was obtained with spherical shape and size of less than 100 nm. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomaterial" title="biomaterial">biomaterial</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=alumina" title=" alumina"> alumina</a>, <a href="https://publications.waset.org/abstracts/search?q=nano%20composite" title=" nano composite"> nano composite</a>, <a href="https://publications.waset.org/abstracts/search?q=precipitation%20method" title=" precipitation method"> precipitation method</a> </p> <a href="https://publications.waset.org/abstracts/31034/percentages-of-alumina-phase-and-different-ph-on-the-ha-al2o3-nano-composite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31034.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">534</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">110</span> Nitrogen, Phosphorus, Potassium (NPK) Hydroxyapatite Nano-Hybrid Slow Release Fertilizer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tinomuvonga%20Manenji%20Zhou">Tinomuvonga Manenji Zhou</a>, <a href="https://publications.waset.org/abstracts/search?q=Eubert%20Mahofa"> Eubert Mahofa</a>, <a href="https://publications.waset.org/abstracts/search?q=Tatenda%20Crispen%20Madzokere"> Tatenda Crispen Madzokere</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The nanostructured formulation can increase fertilizer efficacy and uptake ratio of the soil nutrients in agriculture production and save fertilizer resources. Controlled release modes have properties of both release rate and release pattern of nutrients, for fertilizers that are soluble in water might be correctly controlled. Nanoparticles can reduce the rate at which fertilizer nutrients are in the soil by leaching. A slow release NPK-hydroxyapatite nano hybrid fertilizer was synthesized using exfoliated bentonite as filler material. A simple, scalable method was used to synthesize the nitrogen-phosphorus hydroxyapatite nano fertilizer, where calcium hydroxide, phosphoric acid, and urea were used as precursor material, followed by the incorporation of potassium through a liquid grinding method. The product obtained was an NPK-hydroxyapatite nano hybrid fertilizer. A quantitative analysis was done to determine the percentage of nitrogen, phosphorus, and potassium in the hybrid fertilizer. AAS was used to determine the percentage of potassium in the fertilizer. An accelerated water test was conducted to compare the nutrient release behavior of nutrients between the synthesized NPK-hydroxyapatite nano hybrid fertilizer and commercial NPK fertilizer. The rate of release of Nitrogen, phosphorus, and potassium was significantly lower in the synthesized NPK hydroxyapatite nano hybrid fertilizer than in the convectional NPK fertilizer. The synthesized fertilizer was characterized using XRD. NPK hydroxyapatite nano hybrid fertilizer encapsulated in exfoliated bentonite thus prepared can be used as an environmentally friendly fertilizer formulation which could be extended to solve one of the major problems faced in the global fertilization of low nitrogen, phosphorus, and potassium use efficiency in agriculture. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=NPK%20hydroxyapatite%20nano%20hybrid%20fertilizer" title="NPK hydroxyapatite nano hybrid fertilizer">NPK hydroxyapatite nano hybrid fertilizer</a>, <a href="https://publications.waset.org/abstracts/search?q=bentonite" title=" bentonite"> bentonite</a>, <a href="https://publications.waset.org/abstracts/search?q=encapsulation" title=" encapsulation"> encapsulation</a>, <a href="https://publications.waset.org/abstracts/search?q=low%20release" title=" low release"> low release</a> </p> <a href="https://publications.waset.org/abstracts/163701/nitrogen-phosphorus-potassium-npk-hydroxyapatite-nano-hybrid-slow-release-fertilizer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/163701.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">94</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">109</span> Obtaining High Purity Hydroxyapatite from Bovine Bone: Effect of Chemical and Thermal Treatments</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hernandez%20Pardo%20Diego%20F.">Hernandez Pardo Diego F.</a>, <a href="https://publications.waset.org/abstracts/search?q=Guiza%20Arguello%20Viviana%20R."> Guiza Arguello Viviana R.</a>, <a href="https://publications.waset.org/abstracts/search?q=Coy%20Echeverria%20Ana"> Coy Echeverria Ana</a>, <a href="https://publications.waset.org/abstracts/search?q=Viejo%20Abrante%20Fernando"> Viejo Abrante Fernando</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The biological hydroxyapatite obtained from bovine bone arouses great interest in its application as a material for bone regeneration due to its better bioactive behavior in comparison with synthetic hydroxyapatite. For this reason, the objective of the present investigation was to determine the effect of chemical and thermal treatments in obtaining biological bovine hydroxyapatite of high purity and crystallinity. Two different chemical reagents were evaluated (NaOH and HCl) with the aim to remove the organic matrix of the bovine cortical bone. On the other hand, for analyzing the effect of thermal treatment temperature was ranged between 500 and 1000°C for a holding time of 4 hours. To accomplish the above, the materials before and after the chemical and thermal treatments were characterized by elemental compositional analysis (CHN), infrared spectroscopy by Fourier transform (FTIR), RAMAN spectroscopy, scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and X-ray diffraction (XRD) and energy dispersion X-ray spectroscopy (EDS). The results allowed to establish that NaOH is more effective in the removal of the organic matrix of the bone when compared to HCl, whereas a thermal treatment at 700ºC for 4 hours was enough to obtain biological hydroxyapatite of high purity and crystallinity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bovine%20bone" title="bovine bone">bovine bone</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=biomaterials" title=" biomaterials"> biomaterials</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20treatment" title=" thermal treatment"> thermal treatment</a> </p> <a href="https://publications.waset.org/abstracts/104826/obtaining-high-purity-hydroxyapatite-from-bovine-bone-effect-of-chemical-and-thermal-treatments" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/104826.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">116</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">108</span> Effect of the Experimental Conditions on the Adsorption Capacities in the Removal of Pb2+ from Aqueous Solutions by the Hydroxyapatite Nanopowders</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Oral%20Lacin">Oral Lacin</a>, <a href="https://publications.waset.org/abstracts/search?q=Turan%20Calban"> Turan Calban</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatih%20Sevim"> Fatih Sevim</a>, <a href="https://publications.waset.org/abstracts/search?q=Taner%20Celik"> Taner Celik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, Pb<sup>2+</sup> uptake by the hydroxyapatite nanopowders (n-Hap) from aqueous solutions was investigated by using batch adsorption techniques. The adsorption equilibrium studies were carried out as a function of contact time, adsorbent dosage, pH, temperature, and initial Pb<sup>2+</sup> concentration. The results showed that the equilibrium time of adsorption was achieved within 60 min, and the effective pH was selected to be 5 (natural pH). The maximum adsorption capacity of Pb<sup>2+ </sup>on n-Hap was found as 565 mg.g<sup>-1</sup>. It is believed that the results obtained for adsorption may provide a background for the detailed mechanism investigations and the pilot and industrial scale applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanopowders" title="nanopowders">nanopowders</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=heavy%20metals" title=" heavy metals"> heavy metals</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption" title=" adsorption"> adsorption</a> </p> <a href="https://publications.waset.org/abstracts/52026/effect-of-the-experimental-conditions-on-the-adsorption-capacities-in-the-removal-of-pb2-from-aqueous-solutions-by-the-hydroxyapatite-nanopowders" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52026.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">294</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">107</span> Development of a Biomaterial from Naturally Occurring Chloroapatite Mineral for Biomedical Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20K.%20G.%20K.%20D.%20K.%20Hapuhinna">H. K. G. K. D. K. Hapuhinna</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20D.%20Gunaratne"> R. D. Gunaratne</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20M.%20J.%20C.%20Pitawala"> H. M. J. C. Pitawala</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hydroxyapatite is a bioceramic which can be used for applications in orthopedics and dentistry due to its structural similarity with the mineral phase of mammalian bones and teeth. In this study, it was synthesized, chemically changing natural Eppawala chloroapatite mineral as a value-added product. Sol-gel approach and solid state sintering were used to synthesize products using diluted nitric acid, ethanol and calcium hydroxide under different conditions. Synthesized Eppawala hydroxyapatite powder was characterized using X-ray Fluorescence (XRF), X-ray Powder Diffraction (XRD), Fourier-transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA) and Differential Scanning Calorimetry (DSC) in order to find out its composition, crystallinity, presence of functional groups, bonding type, surface morphology, microstructural features, and thermal dependence and stability, respectively. The XRD results reflected the formation of a hexagonal crystal structure of hydroxyapatite. Elementary composition and microstructural features of products were discussed based on the XRF and SEM results of the synthesized hydroxyapatite powder. TGA and DSC results of synthesized products showed high thermal stability and good material stability in nature. Also, FTIR spectroscopy results confirmed the formation of hydroxyapatite from apatite via the presence of hydroxyl groups. Those results coincided with the FTIR results of mammalian bones including human bones. The study concludes that there is a possibility of producing hydroxyapatite using commercially available Eppawala chloroapatite in Sri Lanka. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dentistry" title="dentistry">dentistry</a>, <a href="https://publications.waset.org/abstracts/search?q=Eppawala%20chlorapatite" title=" Eppawala chlorapatite"> Eppawala chlorapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=orthopedics" title=" orthopedics"> orthopedics</a> </p> <a href="https://publications.waset.org/abstracts/85571/development-of-a-biomaterial-from-naturally-occurring-chloroapatite-mineral-for-biomedical-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85571.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">235</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">106</span> Ceramic Composites and Its Applications for Pb Adsorption</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=C.%20L.%20Popa">C. L. Popa</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20L.%20Iconaru"> S. L. Iconaru</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Costescu"> A. Costescu</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20S.%20Ciobanu"> C. S. Ciobanu</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Motelica%20Heino"> M. Motelica Heino</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Guegan"> R. Guegan</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Predoi"> D. Predoi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Surface functionalization of ceramic composites with a special focus on tetraethyl orthosilicate (TEOS) and hydroxyapatite (HAp) is discoursed. Mesoporous ceramic HAp-TEOS composites were prepared by the incorporation of hydroxyapatite into tetraethyl orthosilicate by sol-gel method. The resulting samples were analysed by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FT-IR) spectroscopy, and Raman spectroscopy and nitrogen physisorption. The removal of Pb2+ ions from aqueous solutions was evaluated using Atomic Absorbtion Spectroscopy (AAS). Removal experiments of Pb2+ ions were carried out in aqueous solutions with controlled Pb2+ at pH ~ 3 and pH ~ 5. After removal experiment of Pb2+ at pH 3 and pH 5, porous hydroxyapatite nanoparticles is transformed into PbHAp_3 and PbHAp_5 via the adsorption of Pb2+ ions followed by the cation exchange reaction. The diffraction patterns show that THAp nanoparticles were successfully coated with teos without any structural changes. On the other, the AAS analysis showed that THAp can be useful in the removal Pb2+ from water contaminated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=teos" title="teos">teos</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=environment%20applications" title=" environment applications"> environment applications</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/2457/ceramic-composites-and-its-applications-for-pb-adsorption" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2457.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">384</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">105</span> Preparation and Characterizations of Hydroxyapatite-Sodium Alginate Nanocomposites for Biomedical Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Friday%20Godwin%20Okibe">Friday Godwin Okibe</a>, <a href="https://publications.waset.org/abstracts/search?q=Christian%20Chinweuba%20Onoyima"> Christian Chinweuba Onoyima</a>, <a href="https://publications.waset.org/abstracts/search?q=Edith%20Bolanle%20Agbaji"> Edith Bolanle Agbaji</a>, <a href="https://publications.waset.org/abstracts/search?q=Victor%20Olatunji%20Ajibola"> Victor Olatunji Ajibola</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Polymer-inorganic nanocomposites are presently impacting diverse areas, specifically in biomedical sciences. In this research, hydroxyapatite-sodium alginate has been prepared, and characterized, with emphasis on the influence of sodium alginate on its characteristics. In situ wet chemical precipitation method was used in the preparation. The prepared nanocomposite was characterized with Fourier Transform Infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), with image analysis, and X-Ray Diffraction (XRD). The FTIR study shows peaks characteristics of hydroxyapatite and confirmed formation of the nanocomposite via chemical interaction between sodium alginate and hydroxyapatite. Image analysis shows the nanocomposites to be of irregular morphologies which did not show significant change with increasing sodium alginate addition, while particle size decreased with increase in sodium alginate addition (359.46 nm to 109.98 nm). From the XRD data, both the crystallite size and degree of crystallinity also decreased with increasing sodium alginate composition (32.36 nm to 9.47 nm and 72.87% to 1.82% respectively), while the specific surface area and microstrain increased with increasing sodium alginate composition (0.0041 to 0.0139 and 58.99 m²/g to 201.58 m²/g respectively). The results show that the formulation with 50%wt of sodium alginate (HASA-50%wt), possess exceptional characteristics for biomedical applications such as drug delivery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanocomposite" title="nanocomposite">nanocomposite</a>, <a href="https://publications.waset.org/abstracts/search?q=sodium%20alginate" title=" sodium alginate"> sodium alginate</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=biomedical" title=" biomedical"> biomedical</a>, <a href="https://publications.waset.org/abstracts/search?q=FTIR" title=" FTIR"> FTIR</a>, <a href="https://publications.waset.org/abstracts/search?q=XRD" title=" XRD"> XRD</a>, <a href="https://publications.waset.org/abstracts/search?q=SEM" title=" SEM"> SEM</a> </p> <a href="https://publications.waset.org/abstracts/66789/preparation-and-characterizations-of-hydroxyapatite-sodium-alginate-nanocomposites-for-biomedical-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66789.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">330</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">104</span> Physico‑chemical Behavior and Microstructural Manipulation of Nanocomposites Containing Hydroxyapatite, Alumina, and Graphene Oxide</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Reim%20A.%20Almotiri">Reim A. Almotiri</a>, <a href="https://publications.waset.org/abstracts/search?q=Manal%20M.%20Alkhamisi"> Manal M. Alkhamisi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ternary nanocomposites based on hydroxyapatite (HAP) and alumina (Al2O3) were embedded through graphene oxide (GO) nanosheets to be investigated for medical applications. The composition of the preparations has been confirmed by X-ray photoelectron spectroscopy, energy-dispersive X-ray analysis, and Fourier-Transform infrared spectroscopy. Scanning and transmission electron microscopy have shown the typical morphologies of the components of the nanocomposites with hydroxyapatite nanorods reaching an average diameter of 22.26±2 nm and an average length of 69.56±19.25 nm in the ternary nanocomposites. The ternary nanocomposite has a microhardness of 5.8±0.1 GPa and a higher average roughness of 6.5 nm compared to pure HAP preparation with an average roughness of 2.7 nm. All preparations have shown an acceptable cytotoxicity profile with a percent osteoblasts cell viability of 98.6±1.3% after culturing with the ternary nanocomposite. The TNC has also shown the highest antibacterial activity compared to preparations of each of its constituents and their nanocomposites, with a zone of inhibition’s diameter of 14.1±0.8 mm and 13.6±0.6 mm against Staphylococcus aureus and Escherichia coli, respectively, compared to no zone of inhibition for the pure hydroxyapatite preparation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydroxypatite" title="hydroxypatite">hydroxypatite</a>, <a href="https://publications.waset.org/abstracts/search?q=cytotoxicity" title=" cytotoxicity"> cytotoxicity</a>, <a href="https://publications.waset.org/abstracts/search?q=nanocomposites" title=" nanocomposites"> nanocomposites</a>, <a href="https://publications.waset.org/abstracts/search?q=X-ray%20analysis" title=" X-ray analysis"> X-ray analysis</a> </p> <a href="https://publications.waset.org/abstracts/161605/physicochemical-behavior-and-microstructural-manipulation-of-nanocomposites-containing-hydroxyapatite-alumina-and-graphene-oxide" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161605.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">83</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">103</span> Synthesis and Characterization of Magnesium and Strontium Doped Sulphate-Hydroxyapatite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ammar%20Z.%20Alshemary">Ammar Z. Alshemary</a>, <a href="https://publications.waset.org/abstracts/search?q=Yi-Fan%20Goh"> Yi-Fan Goh</a>, <a href="https://publications.waset.org/abstracts/search?q=Rafaqat%20Hussain"> Rafaqat Hussain</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Magnesium (Mg2+), strontium (Sr2+) and sulphate ions (SO42-) were successfully substituted into hydroxyapatite (Ca10-x-y MgxSry(PO4)6-z(SO4)zOH2-z) structure through ion exchange process at cationic and anionic sites. Mg2+and Sr2+ ions concentrations were varied between (0.00-0.10), keeping concentration of SO42- ions at z=0.05. [Mg (NO3)2], [Sr (NO3)2] and (Na2SO4) were used as Mg2+, Sr2+, and SO42- sources respectively. The synthesized white precipitate were subjected to heat treatment at 500ºC and finally characterized by X-ray diffraction (XRD) and Fourier Transform infra-red spectroscopy (FTIR). The results showed that the substitution of Mg2+, Sr2+ and SO42- ions into the HA lattice resulted in an increase in the broadness and reduction of XRD peaks. This confirmed that the crystallinity was reduced due to the substitution of ions. Similarly, FTIR result showed the effect of substitution on phosphate bands as well as exchange of hydroxyl group by SO42- ions to balance the charges on HA surface. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title="hydroxyapatite">hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=substitution" title=" substitution"> substitution</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization" title=" characterization"> characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=XRD" title=" XRD"> XRD</a>, <a href="https://publications.waset.org/abstracts/search?q=FTIR" title=" FTIR"> FTIR</a> </p> <a href="https://publications.waset.org/abstracts/14180/synthesis-and-characterization-of-magnesium-and-strontium-doped-sulphate-hydroxyapatite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14180.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">443</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">102</span> Development of Mg-Containing Hydroxyapatite-Based Bioceramics From Phosphate Rock for Bone Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sara%20Mercedes%20Barroso%20Pinz%C3%B3n">Sara Mercedes Barroso Pinzón</a>, <a href="https://publications.waset.org/abstracts/search?q=%C3%81lvaro%20Jes%C3%BAs%20Caicedo%20Castro"> Álvaro Jesús Caicedo Castro</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonio%20Javer%20S%C3%A1nchez%20Herencia"> Antonio Javer Sánchez Herencia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years there has been increased academic and industrial research into the development of orthopaedic implants with structural properties and functionality similar to mechanical strength, osseointegration, thermal stability and antibacterial capacity similar to bone structure. Hydroxyapatite has been considered for decades as an ideal biomaterial for bone regeneration due to its chemical and crystallographic similarity to the mineral structure bioapatites. However, the lack of trace elements in the hydroxyapatite structure confers very low mechanical and biological properties. Under this scenario, the objective of the research is the synthesis of hydroxyapatite with Mg from the francolite mineral present in phosphate rock from the central-eastern region of Colombia, taking advantage of the extraction of mineral species as natural precursors of Ca, P and Mg. The minerals present were studied, fluorapatite as the mineral of interest associated with magnesium carbonates and quartz. The chemical and mineralogical composition was determined by X-ray fluorescence (XRF) and X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX); the optimum conditions were established using the acid leaching mechanism in the wet concentration process. From the products obtained and characterised by XRD, XRF, SEM, FTIR, RAMAN, HAp-Mg biocomposite scaffolds are fabricated and the influence of Mg on morphometric parameters, mechanical and biological properties in the formed materials is evaluated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=phosphate%20rock" title="phosphate rock">phosphate rock</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=magnesium" title=" magnesium"> magnesium</a>, <a href="https://publications.waset.org/abstracts/search?q=biomaterials" title=" biomaterials"> biomaterials</a> </p> <a href="https://publications.waset.org/abstracts/184860/development-of-mg-containing-hydroxyapatite-based-bioceramics-from-phosphate-rock-for-bone-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184860.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">56</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">101</span> Characterisation and in vitro Corrosion Resistance of Plasma Sprayed Hydroxyapatite and Hydroxyapatite: Silicon Oxide Coatings on 316L SS</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gurpreet%20Singh">Gurpreet Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Hazoor%20Singh"> Hazoor Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Buta%20Singh%20Sidhu"> Buta Singh Sidhu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the current investigation plasma spray technique was used for depositing hydroxyapatite (HA) and HA – silicon oxide (SiO2) coatings on 316L SS substrate. In HA-SiO2 coating, 20 wt% SiO2 was mixed with HA. The feedstock and coatings were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM)/energy-dispersive X-ray spectroscopy (EDX) analyses. The corrosion resistance of the uncoated, HA coated and HA + 20 wt% SiO2 coated 316L SS was investigated by electrochemical corrosion testing in simulated human body fluid (Ringer’s solution). The influence of SiO2 (20 wt%) on corrosion resistance was determined. After the corrosion testing, the samples were analyzed by XRD and SEM/EDX analyses. The addition of SiO2 reduces the crystallinity of the coating. The corrosion resistance of the 316L SS was found to increase after the deposition of the HA + 20 wt% SiO2 and HA coatings. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=HA" title="HA">HA</a>, <a href="https://publications.waset.org/abstracts/search?q=SiO2" title=" SiO2"> SiO2</a>, <a href="https://publications.waset.org/abstracts/search?q=corrosion" title=" corrosion"> corrosion</a>, <a href="https://publications.waset.org/abstracts/search?q=Ringer%E2%80%99s%20solution" title=" Ringer’s solution"> Ringer’s solution</a>, <a href="https://publications.waset.org/abstracts/search?q=316L%20SS" title=" 316L SS"> 316L SS</a> </p> <a href="https://publications.waset.org/abstracts/9141/characterisation-and-in-vitro-corrosion-resistance-of-plasma-sprayed-hydroxyapatite-and-hydroxyapatite-silicon-oxide-coatings-on-316l-ss" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9141.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">419</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">100</span> Obtaining Bioactive Mg-hydroxyapatite Composite Ceramics From Phosphate Rock For Medical Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sara%20Mercedes%20Barroso%20Pinz%C3%B3n">Sara Mercedes Barroso Pinzón</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonio%20Javier%20Sanch%C3%A9z%20Herencia"> Antonio Javier Sanchéz Herencia</a>, <a href="https://publications.waset.org/abstracts/search?q=Bego%C3%B1a%20Ferrari"> Begoña Ferrari</a>, <a href="https://publications.waset.org/abstracts/search?q=%C3%81lvaro%20Jes%C3%BAs%20Castro"> Álvaro Jesús Castro</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The current need for durable implants and bone substitutes characterised by biocompatibility, bioactivity and mechanical properties, without immunological rejection, is a major challenge for scientists. Hydroxyapatite (HAp) has been considered for decades as an ideal biomaterial for bone regeneration due to its chemical and crystallographic similarity to the mineral structure bioapatites. However, the lack of trace elements in the hydroxyapatite structure gives it very low mechanical and biological properties. In this sense, the objective of the research is to address the synthesis of hydroxyapatite with Mg from phosphate rock from sedimentary deposits in the central-eastern region of Colombia, taking advantage of the release of the species contained as natural precursors of Ca, P and Mg. The minerals present were studied, fluorapatite as the mineral of interest associated with mineralogical species of magnesium carbonates and quartz. The chemical and mineralogical composition was determined by X-ray fluorescence (XRF) and X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX); as well as the evaluation of the surface physicochemical properties of zeta potential (PZC), with the aim of studying the surface behaviour of the microconstituents present in the phosphate rock and to elucidate the synergistic mechanism between the minerals and establish the optimum conditions for the wet concentration process. From the products obtained and characterised by XRD, XRF, SEM, FTIR, RAMAN, HAp-Mg biocomposite scaffolds are fabricated and the influence of Mg on the morphometric parameters, mechanical and biological properties of the designed materials is evaluated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=phosphate%20rock" title="phosphate rock">phosphate rock</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=magnesium" title=" magnesium"> magnesium</a>, <a href="https://publications.waset.org/abstracts/search?q=biomaterials" title=" biomaterials"> biomaterials</a> </p> <a href="https://publications.waset.org/abstracts/184856/obtaining-bioactive-mg-hydroxyapatite-composite-ceramics-from-phosphate-rock-for-medical-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184856.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">49</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">99</span> Surfactant Free Synthesis of Magnetite/Hydroxyapatite Composites for Hyperthermia Treatment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Sneha">M. Sneha</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Meenakshi%20Sundaram"> N. Meenakshi Sundaram</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent times, magnetic hyperthermia is used for cancer treatment as a tool for active targeting of delivering drugs to the targeted site. It has a potential advantage over other heat treatment because there is no systemic buildup in organs and large doses are possible. The aim of this study is to develop a suitable magnetic biomaterial that can destroy the cancer cells as well as induce bone regeneration. In this work, the composite material was synthesized in two-steps. First, porous iron oxide nano needles were synthesized by hydrothermal process. Second, the hydroxyapatite, were synthesized from natural calcium (i.e., egg shell) and inorganic phosphorous source using wet chemical method. The crystalline nature is confirmed by powder X-ray diffraction analysis (XRD). Thermal analysis and the surface area of the material is studied by Thermo Gravimetric Analysis (TGA), Brunauer-Emmett and Teller (BET) technique. Scanning electron microscope (SEM) images show that the particles have nanoneedle-like morphology. The magnetic property is studied by vibrating sample magnetometer (VSM) technique which confirms the superparamagnetic behavior. This paper presents a simple and easy method for synthesis of magnetite/hydroxyapatite composites materials. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=iron%20oxide%20nano%20needles" title="iron oxide nano needles">iron oxide nano needles</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=superparamagnetic" title=" superparamagnetic"> superparamagnetic</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperthermia" title=" hyperthermia"> hyperthermia</a> </p> <a href="https://publications.waset.org/abstracts/14232/surfactant-free-synthesis-of-magnetitehydroxyapatite-composites-for-hyperthermia-treatment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/14232.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">641</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">98</span> Development and Characterization of Hydroxyapatite Based Nanocomposites for Local Drug Delivery to Periodontal Pockets</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Indu%20Lata%20Kanwar">Indu Lata Kanwar</a>, <a href="https://publications.waset.org/abstracts/search?q=Preeti%20K.%20Suresh"> Preeti K. Suresh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this study is to fabricate hydroxyapatite based nanocomposites for local drug delivery in periodontal pockets. Hydroxyapatite is chemically similar to the mineral component of bones and hard tissues in mammals. Synthetic biocompatibility and bioactivity with human teeth and bone, making it very attractive for biomedical applications. Nanocomposite is a multiphase solid material where one of the phases has one, two or three dimensions of less than 100 nanometres (nm), or structures having nanoscale repeat distances between the different phases that make up the material. Nanostructured calcium phosphate materials play an important role in the formation of hard tissues in nature. It is reported that calcium phosphates materials in nano-size can mimic the dimensions of constituent components of calcified tissues. Nano-sized materials offer improved performances compared with conventional materials due to their large surface-to-volume ratios. The specific biological properties of the nanocomposites, as well as their interaction with cells, include the use of bioactive molecules. The approach of periodontal tissue engineering is considered promising to restore bone defect through the use of engineered materials with the aim that they will prohibit the invasion of ﬁbrous connective tissue and help repair the function during bone regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioactive" title="bioactive">bioactive</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=nanocomposities" title=" nanocomposities"> nanocomposities</a>, <a href="https://publications.waset.org/abstracts/search?q=periondontal" title=" periondontal"> periondontal</a> </p> <a href="https://publications.waset.org/abstracts/47664/development-and-characterization-of-hydroxyapatite-based-nanocomposites-for-local-drug-delivery-to-periodontal-pockets" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47664.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">325</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">97</span> Production and Characterization of Silver Doped Hydroxyapatite Thin Films for Biomedical Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=C.%20L%20Popa">C. L Popa</a>, <a href="https://publications.waset.org/abstracts/search?q=C.S.%20Ciobanu"> C.S. Ciobanu</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20L.%20Iconaru"> S. L. Iconaru</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Chapon"> P. Chapon</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Costescu"> A. Costescu</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Le%20Coustumer"> P. Le Coustumer</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Predoi"> D. Predoi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this paper, the preparation and characterization of silver doped hydroxyapatite thin films and their antimicrobial activity characterized is reported. The resultant Ag: HAp films coated on commercially pure Si disks substrates were systematically characterized by Scanning Electron Microscopy (SEM) coupled with X-ray Energy Dispersive Spectroscopy detector (X-EDS), Glow Discharge Optical Emission Spectroscopy (GDOES) and Fourier Transform Infrared spectroscopy (FT-IR). GDOES measurements show that a substantial Ag content has been deposited in the films. The X-EDS and GDOES spectra revealed the presence of a material composed mainly of phosphate, calcium, oxygen, hydrogen and silver. The antimicrobial efficiency of Ag:HAp thin films against Escherichia coli and Staphylococcus aureus bacteria was demonstrated. Ag:HAp thin films could lead to a decrease of infections especially in the case of bone and dental implants by surface modification of implantable medical devices. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=silver" title="silver">silver</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=thin%20films" title=" thin films"> thin films</a>, <a href="https://publications.waset.org/abstracts/search?q=GDOES" title=" GDOES"> GDOES</a>, <a href="https://publications.waset.org/abstracts/search?q=SEM" title=" SEM"> SEM</a>, <a href="https://publications.waset.org/abstracts/search?q=FTIR" title=" FTIR"> FTIR</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20effect" title=" antimicrobial effect"> antimicrobial effect</a> </p> <a href="https://publications.waset.org/abstracts/2458/production-and-characterization-of-silver-doped-hydroxyapatite-thin-films-for-biomedical-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2458.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">425</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">96</span> Starch Incorporated Hydroxyapatite/Chitin Nanocomposite as a Novel Bone Construct</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Reshma%20Jolly">Reshma Jolly</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Shakir"> Mohammad Shakir</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Shoeb%20Khan"> Mohammad Shoeb Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Noor%20E.%20Iram"> Noor E. Iram</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A nanocomposite system integrating hydroxyapatite, chitin and starch (n-HA/CT/ST) has been synthesized via co-precipitation approach at room temperature, addressing the issues of biocompatibility, mechanical strength and cytotoxicity required for Bone tissue engineering. The interactions, crystallite size and surface morphology against n-HA/CT (nano-hydroxyapatite/chitin) nanocomposite have been obtained by correlating and comparing the results of FTIR, SEM, TEM and XRD. The comparative study of the bioactivity of n-HA/CT and n-HA/CT/ST nanocomposites revealed that the incorporation of starch as templating agent improved these properties in n-HA/CT/ST nanocomposite. The rise in thermal stability in n-HA/CT/ST nanocomposite as compared to n-HA/CT has been observed by comparing the TGA results. The comparison of SEM images of both the scaffolds indicated that the addition of ST influenced the surface morphology of n-HA/CT scaffold which appeared to be rougher and porous. The MTT assay on murine fibroblast L929 cells and in-vitro bioactivity of n-HA/CT/ST matrix referred superior non-toxic property of n-HA/CT/ST nanocomposite and higher possibility of osteo-integration in-vivo, respectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioactive" title="bioactive">bioactive</a>, <a href="https://publications.waset.org/abstracts/search?q=chitin" title=" chitin"> chitin</a>, <a href="https://publications.waset.org/abstracts/search?q=hyroxyapatite" title=" hyroxyapatite"> hyroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=nanocomposite" title=" nanocomposite"> nanocomposite</a> </p> <a href="https://publications.waset.org/abstracts/29631/starch-incorporated-hydroxyapatitechitin-nanocomposite-as-a-novel-bone-construct" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29631.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">493</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">95</span> Drilling Quantification and Bioactivity of Machinable Hydroxyapatite : Yttrium phosphate Bioceramic Composite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rupita%20Ghosh">Rupita Ghosh</a>, <a href="https://publications.waset.org/abstracts/search?q=Ritwik%20Sarkar"> Ritwik Sarkar</a>, <a href="https://publications.waset.org/abstracts/search?q=Sumit%20K.%20Pal"> Sumit K. Pal</a>, <a href="https://publications.waset.org/abstracts/search?q=Soumitra%20Paul"> Soumitra Paul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The use of Hydroxyapatite bioceramics as restorative implants is widely known. These materials can be manufactured by pressing and sintering route to a particular shape. However machining processes are still a basic requirement to give a near net shape to those implants for ensuring dimensional and geometrical accuracy. In this context, optimising the machining parameters is an important factor to understand the machinability of the materials and to reduce the production cost. In the present study a method has been optimized to produce true particulate drilled composite of Hydroxyapatite Yttrium Phosphate. The phosphates are used in varying ratio for a comparative study on the effect of flexural strength, hardness, machining (drilling) parameters and bioactivity.. The maximum flexural strength and hardness of the composite that could be attained are 46.07 MPa and 1.02 GPa respectively. Drilling is done with a conventional radial drilling machine aided with dynamometer with high speed steel (HSS) and solid carbide (SC) drills. The effect of variation in drilling parameters (cutting speed and feed), cutting tool, batch composition on torque, thrust force and tool wear are studied. It is observed that the thrust force and torque varies greatly with the increase in the speed, feed and yttrium phosphate content in the composite. Significant differences in the thrust and torque are noticed due to the change of the drills as well. Bioactivity study is done in simulated body fluid (SBF) upto 28 days. The growth of the bone like apatite has become denser with the increase in the number of days for all the composition of the composites and it is comparable to that of the pure hydroxyapatite. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bioactivity" title="Bioactivity">Bioactivity</a>, <a href="https://publications.waset.org/abstracts/search?q=Drilling" title=" Drilling"> Drilling</a>, <a href="https://publications.waset.org/abstracts/search?q=Hydroxyapatite" title=" Hydroxyapatite"> Hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=Yttrium%20Phosphate" title=" Yttrium Phosphate"> Yttrium Phosphate</a> </p> <a href="https://publications.waset.org/abstracts/39834/drilling-quantification-and-bioactivity-of-machinable-hydroxyapatite-yttrium-phosphate-bioceramic-composite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39834.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">300</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">94</span> The Effects and Interactions of Synthesis Parameters on Properties of Mg Substituted Hydroxyapatite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Sharma">S. Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=U.%20Batra"> U. Batra</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Kapoor"> S. Kapoor</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Dua"> A. Dua</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the effects and interactions of reaction time and capping agent assistance during sol-gel synthesis of magnesium substituted hydroxyapatite nanopowder (MgHA) on hydroxyapatite (HA) to β-tricalcium phosphate (β-TCP) ratio, Ca/P ratio and mean crystallite size was examined experimentally as well as through statistical analysis. MgHA nanopowders were synthesized by sol-gel technique at room temperature using aqueous solution of calcium nitrate tetrahydrate, magnesium nitrate hexahydrate and potassium dihydrogen phosphate as starting materials. The reaction time for sol-gel synthesis was varied between 15 to 60 minutes. Two process routes were followed with and without addition of triethanolamine (TEA) in the solutions. The elemental compositions of as-synthesized powders were determined using X-ray fluorescence (XRF) spectroscopy. The functional groups present in the as-synthesized MgHA nanopowders were established through Fourier Transform Infrared Spectroscopy (FTIR). The amounts of phases present, Ca/P ratio and mean crystallite sizes of MgHA nanopowders were determined using X-ray diffraction (XRD). The HA content in biphasic mixture of HA and β-TCP and Ca/P ratio in as-synthesized MgHA nanopowders increased effectively with reaction time of sols (p < 0.0001, two way Anova), however, these were independent of TEA addition (p > 0.15, two way Anova). The MgHA nanopowders synthesized with TEA assistance exhibited 14 nm lower crystallite size (p < 0.018, 2 sample t-test) compared to the powder synthesized without TEA assistance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=capping%20agent" title="capping agent">capping agent</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=regression%20analysis" title=" regression analysis"> regression analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=sol-gel" title=" sol-gel"> sol-gel</a>, <a href="https://publications.waset.org/abstracts/search?q=2-%20sample%20t-test" title=" 2- sample t-test"> 2- sample t-test</a>, <a href="https://publications.waset.org/abstracts/search?q=two-way%20analysis%20of%20variance%20%28ANOVA%29" title=" two-way analysis of variance (ANOVA)"> two-way analysis of variance (ANOVA)</a> </p> <a href="https://publications.waset.org/abstracts/35507/the-effects-and-interactions-of-synthesis-parameters-on-properties-of-mg-substituted-hydroxyapatite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35507.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">370</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">93</span> Cr³⁺/SiO₄⁴⁻ Codoped Hydroxyapatite Nanorods: Fabrication and Microstructure Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ammar%20Z.%20Alshemary">Ammar Z. Alshemary</a>, <a href="https://publications.waset.org/abstracts/search?q=Zafer%20Evis"> Zafer Evis</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, nanorods of Cr³⁺/SiO₄⁴⁻ codoped hydroxyapatite (Cr³⁺/SiO₄⁴⁻-HA) were synthesized successfully and rapidly through microwave irradiation technique, using (Ca(NO₃)₂•4H₂O), ((NH₄)₂HPO₄), (SiC₈H₂₀O₄) and (Cr(NO₃)₃.9H₂O) as source materials for Ca²⁺, PO₄³⁻, SiO₄⁴⁻ and Cr³⁺ ions, respectively. The impact of dopants on the phase formation and microstructure of the powders were investigated by means of X-ray diffraction (XRD), Fourier transform infrared spectrum analysis (FT-IR) and Field emission electron microscopy (FESEM) techniques. XRD analysis showed that with an incorporation of Cr³⁺/SiO₄⁴⁻ ions into HA structure resulted in peak broadening and reduced peak height due to the amorphous nature and reduced crystallinity of the resulting HA powder. FTIR spectroscopy revealed the existence of the different vibrational modes matching to phosphates and hydroxyl groups. The FESEM analysis showed a change in the crystal shape from spherical to rod shaped particles upon Cr³⁺ doping into the crystal structure. Acknowledgments: This study was supported by Karabük University (Project no. KBÜBAP-17-YD-144). The authors would like to thank for support. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nano-hydroxyapatite" title="nano-hydroxyapatite">nano-hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=microwave" title=" microwave"> microwave</a>, <a href="https://publications.waset.org/abstracts/search?q=dopants" title=" dopants"> dopants</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization" title=" characterization"> characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=microstructure" title=" microstructure"> microstructure</a> </p> <a href="https://publications.waset.org/abstracts/75206/cr3sio44-codoped-hydroxyapatite-nanorods-fabrication-and-microstructure-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/75206.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">227</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">92</span> Thermal Method Production of the Hydroxyapatite from Bone By-Products from Meat Industry</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Agnieszka%20Sobczak-Kupiec">Agnieszka Sobczak-Kupiec</a>, <a href="https://publications.waset.org/abstracts/search?q=Dagmara%20Malina"> Dagmara Malina</a>, <a href="https://publications.waset.org/abstracts/search?q=Klaudia%20Pluta"> Klaudia Pluta</a>, <a href="https://publications.waset.org/abstracts/search?q=Wioletta%20Florkiewicz"> Wioletta Florkiewicz</a>, <a href="https://publications.waset.org/abstracts/search?q=Bozena%20Tyliszczak"> Bozena Tyliszczak</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Request for compound of phosphorus grows continuously, thus, it is searched for alternative sources of this element. One of these sources could be by-products from meat industry which contain prominent quantity of phosphorus compounds. Hydroxyapatite, which is natural component of animal and human bones, is leading material applied in bone surgery and also in stomatology. This is material, which is biocompatible, bioactive and osteoinductive. Methodology: Hydroxyapatite preparation: As a raw material was applied deproteinized and defatted bone pulp called bone sludge, which was formed as waste in deproteinization process of bones, in which a protein hydrolysate was the main product. Hydroxyapatite was received in calcining process in chamber kiln with electric heating in air atmosphere in two stages. In the first stage, material was calcining in temperature 600°C within 3 hours. In the next stage unified material was calcining in three different temperatures (750°C, 850°C and 950°C) keeping material in maximum temperature within 3.0 hours. Bone sludge: Bone sludge was formed as waste in deproteinization process of bones, in which a protein hydrolysate was the main product. Pork bones coming from the partition of meat were used as a raw material for the production of the protein hydrolysate. After disintegration, a mixture of bone pulp and water with a small amount of lactic acid was boiled at temperature 130-135°C and under pressure4 bar. After 3-3.5 hours boiled-out bones were separated on a sieve, and the solution of protein-fat hydrolysate got into a decanter, where bone sludge was separated from it. Results of the study: The phase composition was analyzed by roentgenographic method. Hydroxyapatite was the only crystalline phase observed in all the calcining products. XRD investigation was shown that crystallization degree of hydroxyapatite was increased with calcining temperature. Conclusion: The researches were shown that phosphorus content is around 12%, whereas, calcium content amounts to 28% on average. The conducted researches on bone-waste calcining at the temperatures of 750-950°C confirmed that thermal utilization of deproteinized bone-waste was possible. X-ray investigations were confirmed that hydroxyapatite is the main component of calcining products, and also XRD investigation was shown that crystallization degree of hydroxyapatite was increased with calcining temperature. Contents of calcium and phosphorus were distinctly increased with calcining temperature, whereas contents of phosphorus soluble in acids were decreased. It could be connected with higher crystallization degree of material received in higher temperatures and its stable structure. Acknowledgements: “The authors would like to thank the The National Centre for Research and Development (Grant no: LIDER//037/481/L-5/13/NCBR/2014) for providing financial support to this project”. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20by-products" title="bone by-products">bone by-products</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20sludge" title=" bone sludge"> bone sludge</a>, <a href="https://publications.waset.org/abstracts/search?q=calcination" title=" calcination"> calcination</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a> </p> <a href="https://publications.waset.org/abstracts/51064/thermal-method-production-of-the-hydroxyapatite-from-bone-by-products-from-meat-industry" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/51064.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">286</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">91</span> Preparation and in vitro Characterisation of Chitosan/Hydroxyapatite Injectable Microspheres as Hard Tissue Substitution</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Maachou">H. Maachou</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Chagnes"> A. Chagnes</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Cote"> G. Cote </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present work reports the properties of chitosan/hydroxyapatite (Cs/HA: 100/00, 70/30 and 30/70) composite microspheres obtained by emulsification processing route. The morphology of chitosane microspheres was observed by a scanning electron microscope (SEM) which shows an aggregate of spherical microspheres with a particle size, determined by optical microscope, ranged from 4 to 10 µm. Thereafter, a biomimetic approach was used to study the in vitro biomineralization of these composites. It concerns the composites immersion in simulated body fluid (SBF) for different times. The deposited calcium phosphate was studied using X-ray diffraction analysis (XRD), FTIR spectroscopy and ICP analysis of phosphorus. In fact, the mineral formed on Cs/HA microspheres was a mixture of carbonated HA and β-TCP as showed by FTIR peaks at 1419,5 and 871,8 cm-1 and XRD peak at 29,5°. This formation was induced by the presence of HA in chitosan microspheres. These results are confirmed by SEM micrographs which chow the Ca-P crystals growth in form of cauliflowers. So, these materials are of great interest for bone regeneration applications due to their ability to nucleate calcium phosphates in presence of simulated body fluid (SBF). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title="hydroxyapatite">hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=chitosan" title=" chitosan"> chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=microsphere" title=" microsphere"> microsphere</a>, <a href="https://publications.waset.org/abstracts/search?q=composite" title=" composite"> composite</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20regeneration" title=" bone regeneration"> bone regeneration</a> </p> <a href="https://publications.waset.org/abstracts/12735/preparation-and-in-vitro-characterisation-of-chitosanhydroxyapatite-injectable-microspheres-as-hard-tissue-substitution" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12735.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">330</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">90</span> Bacterial Cellulose/Silver-Doped Hydroxyapatite Composites for Tissue Engineering Application </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Adrian%20Ionut%20Nicoara">Adrian Ionut Nicoara</a>, <a href="https://publications.waset.org/abstracts/search?q=Denisa%20Ionela%20Ene"> Denisa Ionela Ene</a>, <a href="https://publications.waset.org/abstracts/search?q=Alina%20Maria%20Holban"> Alina Maria Holban</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristina%20Busuioc"> Cristina Busuioc</a> </p> <p class="card-text"><strong>Abstract:</strong></p> At present, the development of materials with biomedical applications is a domain of interest that will produce a full series of benefits in engineering and medicine. In this sense, it is required to use a natural material, and this paper is focused on the development of a composite material based on bacterial cellulose – hydroxyapatite and silver nanoparticles with applications in hard tissue. Bacterial cellulose own features like biocompatibility, non-toxicity character and flexibility. Moreover, the bacterial cellulose can be conjugated with different forms of active silver to possess antimicrobial activity. Hydroxyapatite is well known that can mimic at a significant level the activity of the initial bone. The material was synthesized by using an ultrasound probe and finally characterized by several methods. Thereby, the morphological properties were analyzed by using Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). Because the synthesized material has medical application in restore the tissue and to fight against microbial invasion, the samples were tested from the biological point of view by evaluating the biodegradability in phosphate-buffered saline (PBS) and simulated body fluid (SBF) and moreover the antimicrobial effect was performed on Gram-positive bacterium Staphylococcus aureus, Gram-negative bacterium Escherichia coli, and fungi Candida albicans. The results reveal that the obtained material has specific characteristics for bone regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bacterial%20cellulose" title="bacterial cellulose">bacterial cellulose</a>, <a href="https://publications.waset.org/abstracts/search?q=biomaterials" title=" biomaterials"> biomaterials</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=scaffolds%20materials" title=" scaffolds materials"> scaffolds materials</a> </p> <a href="https://publications.waset.org/abstracts/116145/bacterial-cellulosesilver-doped-hydroxyapatite-composites-for-tissue-engineering-application" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/116145.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">133</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">89</span> Hydroxyapatite-Chitosan Composites for Tissue Engineering Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Georgeta%20Voicu">Georgeta Voicu</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristina%20Daniela%20Ghitulica"> Cristina Daniela Ghitulica</a>, <a href="https://publications.waset.org/abstracts/search?q=Andreia%20Cucuruz"> Andreia Cucuruz</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristina%20Busuioc"> Cristina Busuioc</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the field of tissue engineering, the compositional and microstructural features of the employed materials play an important role, with implications on the mechanical and biological behaviour of the medical devices. In this context, the development of apatite - natural biopolymer composites represents a choice of many scientific groups. Thus, hydroxyapatite powders were synthesized by a wet method, namely co-precipitation, starting from high purity reagents (CaO, MgO, and H3PO4). Moreover, the substitution of calcium with magnesium have been approached, in the 5 - 10 wt.% range. Afterward, the phosphate powders were integrated in two types of composites with chitosan, different from morphological point of view. First, 3D porous scaffolds were obtained by a freeze-drying procedure. Second, uniform, compact films were achieved by film casting. The influence of chitosan molecular weight (low, medium and high), as well as apatite powder to polymer ratio (1:1 and 1:2) on the morphological properties, were analysed in detail. In conclusion, the reported biocomposites, prepared by a straightforward route are suitable for bone substitution or repairing applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20reconstruction" title="bone reconstruction">bone reconstruction</a>, <a href="https://publications.waset.org/abstracts/search?q=chitosan" title=" chitosan"> chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=composite%20scaffolds" title=" composite scaffolds"> composite scaffolds</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a> </p> <a href="https://publications.waset.org/abstracts/62705/hydroxyapatite-chitosan-composites-for-tissue-engineering-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62705.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">322</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">88</span> Effect of Copper Ions Doped-Hydroxyapatite 3D Fiber Scaffold </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Adil%20Elrayah">Adil Elrayah</a>, <a href="https://publications.waset.org/abstracts/search?q=Jie%20Weng"> Jie Weng</a>, <a href="https://publications.waset.org/abstracts/search?q=Esra%20Suliman"> Esra Suliman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The mineral in human bone is not pure stoichiometric calcium phosphate (Ca/P) as it is partially substituted by in organic elements. In this study, the copper ions (Cu<sup>2+</sup>) substituted hydroxyapatite (CuHA) powder has been synthesized by the co-precipitation method. The CuHA powder has been used to fabricate CuHA fiber scaffolds by sol-gel process and the following sinter process. The resulted CuHA fibers have slightly different microstructure (i.e. porosity) compared to HA fiber scaffold, which is denser. The mechanical properties test was used to evaluate CuHA, and the results showed decreases in both compression strength and hardness tests. Moreover, the <em>in vitro</em> used endothelial cells to evaluate the angiogenesis of CuHA. The result illustrated that the viability of endothelial cell on CuHA fiber scaffold surfaces tends to antigenic behavior. The results obtained with CuHA scaffold give this material benefit in biological applications such as antimicrobial, antitumor, antigens, compacts, filling cavities of the tooth and for the deposition of metal implants anti-tumor, anti-cancer, bone filler, and scaffold. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fiber%20scaffold" title="fiber scaffold">fiber scaffold</a>, <a href="https://publications.waset.org/abstracts/search?q=copper%20ions" title=" copper ions"> copper ions</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=in%20vitro" title=" in vitro"> in vitro</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20property" title=" mechanical property"> mechanical property</a> </p> <a href="https://publications.waset.org/abstracts/98364/effect-of-copper-ions-doped-hydroxyapatite-3d-fiber-scaffold" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98364.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">87</span> Clinicoradiographic Evaluation of Polymer of Injectable Platelet-Rich Fibrin (i-PRF) and Hydroxyapatite as Bone Graft Substitute in Maxillomandibular Bony Defects: A Double-Blinded Randomized Control Trial</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Naqoosh%20Haidry">Naqoosh Haidry</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective & Goal: Enucleation of the maxillomandibular cysts will lead to the creation of post-surgical bone defects which may take more than a year for complete bone healing. The use of bone grafts is common to aid bone regeneration in large defects. The study aimed to evaluate the healing and bone formation capabilities of polymer of injectable platelet fibrin (i-PRF) and hydroxyapatite (HA) as bone graft substitute in maxilla-mandibular postsurgical defects compared to hydroxyapatite alone. The primary objective was to find out the clinical and radiological assessment of healing postoperatively and compare the outcome of both groups. Material and Methods: After surgical enucleation of 19 maxillomandibular cysts/tumors, either HA or HA+ i-PRF graft was adapted to the defect. Clinical outcome variables such as pain (VAS score), edema, and mucosal color were evaluated on postoperative days 01, 03, and 07 while radiological outcome variables such as volume of defect (cc), density of new bone (HU) on computed tomography were evaluated at 2nd and 4th month. The results obtained were tabulated and compared with the inferential analysis. Results: Clinical parameters seem to be better in the HA + i-PRF group, but the result was non-significant. Radiologically, the mean healing ratios were significantly greater in the HA + i-PRF group (63.5 ± 2.34 at 2nd month, 90.3 ± 7.32 at 4th month) compared to the HA group (57.2 ± 5.21at 2nd month, 80.8 ± 5.33 at 4th month). When comparing the mean density of new bone, there was a statistically significant difference with a mean difference of 95.2 HU more in the HA + i-PRF (623 HU ± 42.9) compared to the HA group (528 HU ± 96.5) in 2nd month. Conclusion: The polymer of i-PRF and HA prepared as the sticky bone yields faster and better bone healing in post-enucleation maxillomandibular bony defects as compared to hydroxyapatite alone based on radiological findings till four months. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20defect" title="bone defect">bone defect</a>, <a href="https://publications.waset.org/abstracts/search?q=density%20of%20new%20bone" title=" density of new bone"> density of new bone</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=injectable%20platelet%20rich%20fibrin" title=" injectable platelet rich fibrin"> injectable platelet rich fibrin</a>, <a href="https://publications.waset.org/abstracts/search?q=maxillomandibular%20cysts" title=" maxillomandibular cysts"> maxillomandibular cysts</a>, <a href="https://publications.waset.org/abstracts/search?q=surgical%20defect" title=" surgical defect"> surgical defect</a> </p> <a href="https://publications.waset.org/abstracts/184467/clinicoradiographic-evaluation-of-polymer-of-injectable-platelet-rich-fibrin-i-prf-and-hydroxyapatite-as-bone-graft-substitute-in-maxillomandibular-bony-defects-a-double-blinded-randomized-control-trial" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184467.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">48</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">86</span> The Effect of Surface Modified Nano-Hydroxyapatite Incorporation into Polymethylmethacrylate Cement on Biocompatibility and Mechanical Properties</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yu-Shan%20Wu">Yu-Shan Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=Po-Liang%20Lai"> Po-Liang Lai</a>, <a href="https://publications.waset.org/abstracts/search?q=I-Ming%20Chu"> I-Ming Chu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Poly(methylmethacrylate)(PMMA) is the most frequently used bone void filler for vertebral augmentation in osteoporotic fracture. PMMA bone cement not only exhibits strong mechanical properties but also can fabricate according to the shape of bone defect. However, the adhesion between the PMMA-based cement and the adjacent bone is usually weak and as PMMA bone cement is inherently bioinert. The combination of bioceramics and polymers as composites may increase cell adhesion and improve biocompatibility. The nano-hydroxyapatite(HAP) not only plays a significant role in maintaining the properties of the natural bone but also offers a favorable environment for osteoconduction, protein adhesion, and osteoblast proliferation. However, defects and cracks can form at the polymer/ceramics interface, resulting in uneven distribution of stress and subsequent inferior mechanical strength. Surface-modified HAP nano-crystals were prepared by chemically grafting poly(ε-caprolactone)(PCL) on surface-modified nano-HAP surface to increase the affinity of polymer/ceramic phases .Thus, incorporation of surface-modified nano-hydroxyapatite (EC-HAP) may not only improve the interfacial adhesion between cement and bone and between nanoparticles and cement, but also increase biocompatibility. In this research, PMMA mixing with 0, 5, 10, 15, 20, 25 and 30 wt% EC-HAP were examined. MC3T3-E1 cells were used for the biological evaluation of the response to the cements in vitro. Morphology was observed using scanning electron microscopy (SEM). Mechanical properties of HAP/PMMA and EC-HAP/PMMA cement were investigated by compression test. Surface wettability of the cements was measured by contact angles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20cement" title="bone cement">bone cement</a>, <a href="https://publications.waset.org/abstracts/search?q=biocompatibility" title=" biocompatibility"> biocompatibility</a>, <a href="https://publications.waset.org/abstracts/search?q=nano-hydroxyapatite" title=" nano-hydroxyapatite"> nano-hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=polycaprolactone" title=" polycaprolactone"> polycaprolactone</a>, <a href="https://publications.waset.org/abstracts/search?q=PMMA" title=" PMMA"> PMMA</a>, <a href="https://publications.waset.org/abstracts/search?q=surface%20grafting" title=" surface grafting"> surface grafting</a> </p> <a href="https://publications.waset.org/abstracts/45200/the-effect-of-surface-modified-nano-hydroxyapatite-incorporation-into-polymethylmethacrylate-cement-on-biocompatibility-and-mechanical-properties" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45200.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">395</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">85</span> Efficacy of Combined CHAp and Lanthanum Carbonate in Therapy for Hyperphosphatemia </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Andreea%20C%C3%A2r%C3%A2c">Andreea Cârâc</a>, <a href="https://publications.waset.org/abstracts/search?q=Elena%20Morosan"> Elena Morosan</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Corina%20Ionita"> Ana Corina Ionita</a>, <a href="https://publications.waset.org/abstracts/search?q=Rica%20Bosencu"> Rica Bosencu</a>, <a href="https://publications.waset.org/abstracts/search?q=Geta%20Carac"> Geta Carac</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lanthanum carbonate exhibits a considerable ability to bind phosphate and the substitution of Ca2+ ions by divalent or trivalent lanthanide metal ions attracted attention during the past few years. Although Lanthanum carbonate has not been approved by the FDA for treatment of hyperphosphatemia, we prospectively evaluated the efficacy of the combination of Calcium hydroxyapatite and Lanthanum carbonate for the treatment of hyperphosphatemia on mice. Calcium hydroxyapatite commonly referred as CHAp is a bioceramic material and is one of the most important implantable materials due to its biocompatibility and osteoconductivity. We prepared calcium hydroxyapatite and lanthanum carbonate. CHAp was prepared by co-precipitation method using Ca(OH)2, H3PO4, NH4OH with calcination at 1200ºC. Lanthanum carbonate was prepared by chemical method using NaHCO3 and LaCl3 at low pH environment , ph below 4.0 The confirmation of both substances structures was made using XRD characterization, FTIR spectra and SEM /EDX analysis. The study group included 20 subjects-mice divided into four groups according to the administered substance: lanthanum carbonate (group A), lanthanum carbonate + CHAp (group B), CHAp (group C) and salt water (group D). The results indicate a phosphate decrease when subjects (mice) were treated with CHAp and lanthanum carbonate (0.5 % CMC), in a single dose of 1500 mg/kg. Serum phosphate concentration decreased [from 4.5 ± 0.8 mg/dL) to 4.05 ± 0.2 mg/dL), P < 0.01] in group A and to 3.6 ± 0.2 mg/dL] only after the 24 hours of combination therapy. The combination of CHAp and lanthanum carbonate is a suitable regimen for hyperphosphatemia treatment subjects because it avoids both the hypercalcemia of CaCO3 and the adverse effects of CHAp. The ability of CHAp to decrease the serum phosphate concentration is 1/3 that of lanthanum carbonate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calcium%20hydroxyapatite" title="calcium hydroxyapatite">calcium hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperphosphatemia" title=" hyperphosphatemia"> hyperphosphatemia</a>, <a href="https://publications.waset.org/abstracts/search?q=lanthanum%20carbonate" title=" lanthanum carbonate"> lanthanum carbonate</a>, <a href="https://publications.waset.org/abstracts/search?q=phosphate" title=" phosphate"> phosphate</a>, <a href="https://publications.waset.org/abstracts/search?q=structures" title=" structures"> structures</a> </p> <a href="https://publications.waset.org/abstracts/16361/efficacy-of-combined-chap-and-lanthanum-carbonate-in-therapy-for-hyperphosphatemia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16361.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">378</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">84</span> A 3D Bioprinting System for Engineering Cell-Embedded Hydrogels by Digital Light Processing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jimmy%20Jiun-Ming%20Su">Jimmy Jiun-Ming Su</a>, <a href="https://publications.waset.org/abstracts/search?q=Yuan-Min%20Lin"> Yuan-Min Lin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bioprinting has been applied to produce 3D cellular constructs for tissue engineering. Microextrusion printing is the most common used method. However, printing low viscosity bioink is a challenge for this method. Herein, we developed a new 3D printing system to fabricate cell-laden hydrogels via a DLP-based projector. The bioprinter is assembled from affordable equipment including a stepper motor, screw, LED-based DLP projector, open source computer hardware and software. The system can use low viscosity and photo-polymerized bioink to fabricate 3D tissue mimics in a layer-by-layer manner. In this study, we used gelatin methylacrylate (GelMA) as bioink for stem cell encapsulation. In order to reinforce the printed construct, surface modified hydroxyapatite has been added in the bioink. We demonstrated the silanization of hydroxyapatite could improve the crosslinking between the interface of hydroxyapatite and GelMA. The results showed that the incorporation of silanized hydroxyapatite into the bioink had an enhancing effect on the mechanical properties of printed hydrogel, in addition, the hydrogel had low cytotoxicity and promoted the differentiation of embedded human bone marrow stem cells (hBMSCs) and retinal pigment epithelium (RPE) cells. Moreover, this bioprinting system has the ability to generate microchannels inside the engineered tissues to facilitate diffusion of nutrients. We believe this 3D bioprinting system has potential to fabricate various tissues for clinical applications and regenerative medicine in the future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioprinting" title="bioprinting">bioprinting</a>, <a href="https://publications.waset.org/abstracts/search?q=cell%20encapsulation" title=" cell encapsulation"> cell encapsulation</a>, <a href="https://publications.waset.org/abstracts/search?q=digital%20light%20processing" title=" digital light processing"> digital light processing</a>, <a href="https://publications.waset.org/abstracts/search?q=GelMA%20hydrogel" title=" GelMA hydrogel"> GelMA hydrogel</a> </p> <a href="https://publications.waset.org/abstracts/90711/a-3d-bioprinting-system-for-engineering-cell-embedded-hydrogels-by-digital-light-processing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90711.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">181</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=hydroxyapatite&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=hydroxyapatite&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=hydroxyapatite&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=hydroxyapatite&page=2" rel="next">&rsaquo;</a></li> </ul> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); });*/ jQuery.get({ url: "https://publications.waset.org/xhr/user-menu", cache: false }).then(function(response){ jQuery('#mainNavMenu').append(response); }); }); </script> </body> </html>