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Tomorrow's Medicine. | Genome Sciences Centre</title> <link rel="stylesheet" href="//use.typekit.net/rew6qot.css"> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/ajax-progress.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/align.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/autocomplete-loading.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/fieldgroup.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/container-inline.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/clearfix.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/details.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/hidden.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/item-list.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/js.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/nowrap.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/position-container.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/progress.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/reset-appearance.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/resize.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/sticky-header.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/system-status-counter.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/system-status-report-counters.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/system-status-report-general-info.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/tabledrag.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/tablesort.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/core/themes/stable/css/system/components/tree-child.module.css?ss77gc" /> <link rel="stylesheet" media="all" href="/modules/addtoany/css/addtoany.css?ss77gc" /> <link rel="stylesheet" media="all" href="/modules/contrib/paragraphs/css/paragraphs.unpublished.css?ss77gc" /> <link rel="stylesheet" media="all" href="//cdnjs.cloudflare.com/ajax/libs/font-awesome/4.7.0/css/font-awesome.min.css" /> <link rel="stylesheet" media="all" href="//stackpath.bootstrapcdn.com/bootstrap/4.4.1/css/bootstrap.min.css" /> <link rel="stylesheet" media="all" href="/themes/custom/bccrc/assets/libraries/css/styles.css?ss77gc" /> <link rel="stylesheet" media="all" href="/themes/custom/bccrc/assets/libraries/css/custom.css?ss77gc" /> <link rel="stylesheet" media="all" href="//cdnjs.cloudflare.com/ajax/libs/animate.css/3.7.2/animate.min.css" />  <script src="//cdnjs.cloudflare.com/ajax/libs/wow/1.1.2/wow.min.js"></script> </head> <body class="colour--navy not-front path--node page--page"> <a href="#main-content" class="visually-hidden focusable skip-link"> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div class="main-container"> <header class="page--page page"> <div class="region__header--inner region--inner"> <section id="block-bccrc-breadcrumbs" class="block block--system-breadcrumb-block block-bccrc-breadcrumbs"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">GSC</a> </li> <li> Today's Research. Tomorrow's Medicine. </li> </ol> </nav> </section> <section id="block-bccrc-page-title" class="block block--page-title-block block-bccrc-page-title"> <h1><span property="schema:name">Today's Research. Tomorrow's Medicine.</span> </h1> </section> </div> </header> <section class="region region__highlight"> <div class="region__highlight--inner region--inner"> <div data-drupal-messages-fallback class="hidden"></div> </div> </section> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <section class="region region__content"> <div class="region__content--inner region--inner"> <section id="block-bccrc-content" class="block block--system-main-block block-bccrc-content"> <article role="article" about="/about-us" typeof="schema:WebPage" class="node node--page full"> <span property="schema:name" content="Today's Research. Tomorrow's Medicine." class="hidden"></span> <div property="schema:text" class="field field--body"><h3>We are experts in genomics, proteomics, bioinformatics and molecular biology technology development, providing clinical services for BC Cancer and collaborating on research projects around the world.</h3> <h4>聽</h4> <div class="youtube-embed-wrapper"><iframe allow="autoplay; fullscreen" allowfullscreen="" frameborder="0" height="360" src="https://player.vimeo.com/video/374613728" width="640"></iframe></div></div> </article> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--312"> <h2 class="section__title" data-expand="field--field_text">Our Technology Platform</h2> <div class="field field--field_expanding_summary">A key element of the GSC is the sequencing, bioinformatics and proteomics platforms. With world-renowned expertise in genomics research and internationally-recognized bioinformatic capabilities, the GSC operates a platform to support researchers and collaborators in Canada and around the world.</div> <button class="icon" data-expand></button> <div class="field field--field_text"> <p>We partner with researchers, guide experimental design, execute high quality processing of complex and valuable biological samples and provide extensive bioinformatics analyses with the aim of making genomics research accessible to our partners and collaborators within the scientific community.</p> <p>The priority of the platforms is to develop innovative means to automate the sequencing process, develop cost-effective measures that will make such research financially viable, and utilize leading edge computing tools to collect, mine, analyze and disperse data collected at this and other genome facilities. To accomplish this, the platform fully exploits the most recent technological advances in genomics, proteomics, and high performance computing, within a state-of-the-art facility designed to generate and extract information from complex samples and valuable sample collections, for the benefit and use of the wider scientific community.</p> <p>Learn more about our <a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="82165b81-8bc1-4a90-8341-651784775786" href="https://www.bcgsc.ca/about-us/technology-platforms" title="Technology Platforms">platforms</a> and <a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="135724e3-2362-4712-8cc4-63f4ef7b0062" href="https://www.bcgsc.ca/services" title="Collaborative Services">services</a>, and if you are interested in partnering with the GSC on your research project, please fill out a聽<a href="https://www.bcgsc.ca/form/service-request?service=526">contact form聽</a>or speak with one of our聽<a href="https://www.bcgsc.ca/people/directors-platform-leaders">Platform Leaders</a>聽directly.聽聽聽</p></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--313"> <h2 class="section__title" data-expand="field--field_text">Our Scientific Research</h2> <div class="field field--field_expanding_summary">The GSC is one of nine research departments and programs that operate as part of the聽BC Cancer Research Centre. BC Cancer, part of the聽Provincial Health Services Authority, provides a province-wide cancer control program for the residents of British Columbia. Additional support is provided by funds raised by the聽BC Cancer Foundation聽for cancer research.</div> <button class="icon" data-expand></button> <div class="field field--field_text"> <p>The 15聽<a href="https://www.bcgsc.ca/people/faculty">faculty members</a> at the GSC have a diverse range of expertise in genomics, bioinformatics, proteomics, epigenomics, immunogenetics and cancer biology. Together, we broadly apply our expertise to advance our knowledge of cancer and other diseases, to improve human health through disease prevention, to develop diagnostic and therapeutic approaches and to realize the social and economic benefits of genomics research.</p> <p>The overarching themes of our research programs are described below.聽Learn more about <a href="https://www.bcgsc.ca/people/faculty">faculty</a> and some of their research projects <a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="2b4fd57d-b796-42ff-84f8-9d8f5204ae5a" href="https://www.bcgsc.ca/research" title="Research">here</a>.</p></div> </section> <section class="layout layout__columns layout__parent__node paragraph paragraph--type--columns paragraph--view-mode--default" id="paragraph--309"> <div class="columns columns--4"> <h2 class="section__title">Cancer</h2> <div class="layout layout__column layout__parent__paragraph paragraph paragraph--type--column paragraph--view-mode--default" id="paragraph--305"> <img src="/sites/default/files/styles/teaser/public/2019-10/skbr3_starved.jpg?itok=lDrgVtuB" width="600" height="450" alt="" typeof="foaf:Image" /> <div class="field--field_paragraph_text"> <p>The GSC is <a href="https://www.bcgsc.ca/sites/default/files/certificates/CAP%20Certificate%20Feb%202019%20-%20Feb%202021.pdf">CAP</a>, <a href="https://www.bcgsc.ca/sites/default/files/certificates/DAP%20Certificate%202021-2026.pdf">DAP</a> and <a href="https://www.bcgsc.ca/sites/default/files/Genome%20Sciences%20Certificate.pdf">ISO</a> certified, allowing us to perform clinical sequencing to detect cancer susceptibility mutations through capture panels and whole genome sequencing. Cancer research and clinical programs include:聽</p> <ul><li><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="fa42315e-a4de-4785-959c-26bbc66a92e1" href="https://www.bcgsc.ca/node/869" title="What is Personalized OncoGenomics (POG)?">Personalized OncoGenomics</a></li> <li><a href="https://ccgenomics.com/">Centre for Clinical Genomics</a></li> <li><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="f2e401af-c610-4d6c-bf55-0cf96890095a" href="https://www.bcgsc.ca/projects/lymphoid-cancer-families-study" title="Lymphoid Cancer Families Study">Lymphoma Families Study</a></li> <li><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="e38330bd-9828-4409-8d39-d117feeb5345" href="https://www.bcgsc.ca/projects/metagenomics-infectious-agents-cancer" title="Metagenomics - Infectious agents in Cancer">Microbes and聽colorectal cancer </a></li> <li><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="868397de-61b0-45c2-abdf-53cb5ebddf73" href="https://www.bcgsc.ca/projects/prostate-cancer-therapeutics" title="Prostate cancer therapeutics">Prostate cancer therapies</a></li> <li>And many more</li> </ul> </div> </div> <h2 class="section__title">Health</h2> <div class="layout layout__column layout__parent__paragraph paragraph paragraph--type--column paragraph--view-mode--default" id="paragraph--306"> <img src="/sites/default/files/styles/teaser/public/2019-10/close-up-elder-elderly-2050994.jpg?itok=n5UEtae_" width="600" height="450" alt="" typeof="foaf:Image" /> <div class="field--field_paragraph_text"> <p>In addition to cancer research, scientist at the GSC are using genomics to tackle tough questions related to human health including:聽</p> <ul><li><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="7a77cb0f-1a76-49d9-b992-5dcad53f0be5" href="https://www.bcgsc.ca/projects/healthy-aging-study" title="The Healthy Aging Study">Healthy Aging</a>聽</li> <li><a href="https://www.ncbi.nlm.nih.gov/pubmed/27748065" target="_blank" title="American Journal of Medical Genetics">Intellectual disability</a>聽</li> <li><a href="http://pegasus-pegase.ca/" target="_blank" title="Pegasus">Prenatal testing</a>聽</li> <li><a data-entity-substitution="canonical" data-entity-type="node" data-entity-uuid="aab90d29-2a81-4c0d-b5bd-ae8b3ea08d07" href="https://www.bcgsc.ca/labs/hirst-lab-epigenomics-lab" title="Hirst Lab / Epigenomics Lab">Epigenomics research</a> (<a href="http://www.epigenomes.ca/" target="_blank" title="Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC) Network">across Canada</a>聽and聽<a href="http://ihec-epigenomes.org/" target="_blank" title="International Human Epigenome Consortium">Internationally</a>)</li> </ul> </div> </div> <h2 class="section__title">Disease</h2> <div class="layout layout__column layout__parent__paragraph paragraph paragraph--type--column paragraph--view-mode--default" id="paragraph--307"> <img src="/sites/default/files/styles/teaser/public/2019-12/Cellular-virus-wallpaper.jpg?itok=WPJUVzag" width="600" height="450" alt="" typeof="foaf:Image" /> <div class="field--field_paragraph_text"> <p>The GSC is collaborating on the聽COVID-19 Host Genome Sequencing project (<a href="https://www.cgen.ca/project-overview" target="_blank">HostSeq</a>) to develop a聽national databank containing genome sequences, medical and聽clinical data from 10,000 individuals affected by COVID19.聽In the past, scientists at the GSC have also聽been involved in:</p> <ul><li>The rapid sequencing of the<a href="http://science.sciencemag.org/content/300/5624/1399.full" target="_blank" title="Science">聽SARS Coronavirus</a>聽during the global outbreak in 2003, becoming the first in the world to sequence the virus</li> <li>Sequencing and genome analysis of the<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323367/" target="_blank" title="Emerging Infectious Diseases">聽avian flu (H7N3)</a>聽</li> <li><a href="http://www.nejm.org/doi/full/10.1056/NEJMoa1003176" target="_blank" title="New England Journal of Medicine">Tuberculosis outbreak tracking</a></li> </ul> </div> </div> <h2 class="section__title">Life</h2> <div class="layout layout__column layout__parent__paragraph paragraph paragraph--type--column paragraph--view-mode--default" id="paragraph--308"> <img src="/sites/default/files/styles/teaser/public/2022-04/CBP%20logo%20and%20beaver.png?itok=-7SUY3hT" width="600" height="450" alt="" typeof="foaf:Image" /> <div class="field--field_paragraph_text"> <p>The GSC is聽part of the聽<a href="http://earthbiogenome.ca/">Canada BioGenome Project</a>, which aims to sequence the<a href="https://www.bcgsc.ca/news/canada-biogenome-project-joins-international-quest-understand-life-earth" target="_blank">聽genomes of聽400 iconic Canadian Species</a>. Species already sequenced through聽<a href="http://www.cgen.ca/canseq150" target="_blank">CanSeq150</a> include:</p> <ul><li><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943200/" target="_blank" title="Science">Cattle</a>聽</li> <li><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965382/" target="_blank" title="Genome Biology">Salmon</a>聽</li> <li><a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1755-0998.2010.02960.x/abstract;jsessionid=740EF1EAE1DF2EE038F616B653357A24.f03t02" target="_blank" title="Molecular Ecology Resources">Poplar</a>聽and聽<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673215/" target="_blank" title="Bioinformatics (Oxford)">spruce trees</a></li> <li><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053930/" target="_blank" title="Genome Biology">Mountain pine beetle</a></li> <li><a href="http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130720" target="_blank" title="PLOS One">Amphibian sentinel species</a></li> <li><a href="http://www.sciencedirect.com/science/article/pii/S0378111907003976" target="_blank" title="Gene">Wine grapes</a></li> <li><a href="https://www.bcgsc.ca/news/giants-dot-lichen" target="_blank">Giant鈥檚 Dot Lichen</a></li> <li><a href="https://www.bcgsc.ca/news/sequencing-spruce-weevil-genome" target="_blank">Spruce Weevil</a></li> <li>And many more</li> </ul> </div> </div> </div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="support-and-funding"> <h2 class="section__title" data-expand="field--field_text">Support and Funding</h2> <div class="field field--field_expanding_summary">The Genome Sciences Centre acknowledges the BC Cancer Foundation for its funding support, as well as these additional partnerships, consortia聽and organizations for their contributions to infrastructure and operations.</div> <button class="icon" data-expand></button> <div class="field field--field_text"> <blockquote class="logosgrid"> <p><a href="https://bccancerfoundation.com/"><img alt="BC Cancer Foundation" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/BC%20Cancer%20Foundation.svg" /></a></p> <p><a href="http://www.bccancer.bc.ca/"><img alt="BC Cancer" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/BC%20Cancer_1.PNG" /></a></p> <p><a href="http://www.cgen.ca/"><img alt="CGEN" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/CGEN_0.PNG" /></a></p> <p><a href="http://www.cihr-irsc.gc.ca/"><img alt="CIHR" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/cihr-logo.png" /></a></p> <p><a href="https://www.msfhr.org/"><img alt="MSFHR" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/MSFHR_0.PNG" /></a></p> <p><a href="https://www.societederecherchesurlecancer.ca/en"><img alt="Cancer Research Society" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/CRS_0.PNG" /></a></p> <p><a href="http://www.prostatecancer.ca/"><img alt="prostate cancer canada" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Prostate%20cancer%20canada.png" /></a></p> <p><a href="http://www.nserc.ca/"><img alt="NSERC" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/NSERC.png" /></a></p> <p><a href="https://www.wd-deo.gc.ca/eng/home.asp"><img alt="Western Economic Diversification" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Western%20Economic%20Diversification%20Canada.png" /></a></p> <p><a href="https://www.terryfox.org"><img alt="Terry Fox Foundation" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Terry%20Fox.png" /></a></p> <p><a href="https://www.nih.gov/"><img alt="NIH" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/NIH.png" /></a></p> <p><a href="https://www.genomecanada.ca/"><img alt="Genome Canada" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Genome%20Canada.png" /></a></p> <p><a href="https://www.genomebc.ca/"><img alt="Genome BC" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Genome%20BC.png" /></a></p> <p><a href="http://www.cancer.ca/en/about-us/a-future-without-breast-cancer/"><img alt="Canadian Breast Cancer Foundation" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Canadian%20breast%20cancer%20foundation.png" /></a></p> <p><a href="https://www.innovation.ca/"><img alt="CFI" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/CFI.png" /></a></p> <p><a href="http://www.cancer.ca/research"><img alt="Canadian Cancer Society" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Canadian%20Cancer%20Society.jpg" /></a></p> <p><a href="https://www2.gov.bc.ca/gov/content/governments/organizational-structure/ministries-organizations/ministries/jobs-trade-and-technology"><img alt="British Columbia" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Government%20of%20BC.png" /></a></p> <p><a href="https://www.lionsclubs.org/en"><img alt="Lions Club" data-entity-type="" data-entity-uuid="" src="https://www.bcgsc.ca/sites/genomesciences/files/GSC/Lions%20Club.png" /></a></p> </blockquote></div> </section> <section class="layout layout__expanding layout__parent__node has-expanding-text paragraph paragraph--type--expanding paragraph--view-mode--default" id="paragraph--584"> <h2 class="section__title" data-expand="field--field_text">Acknowledgments</h2><button class="icon" data-expand></button> <div class="field field--field_text"> <p>Graphical images on this site were created using <a href="https://biorender.com/">Biorender.com.</a></p></div> </section> </section> </div> </section> </div> <a class="top" href="#main-content">Back to top</a> </main> <section class="region region__cta"> <div class="region__cta--inner region--inner"> <section id="block-sitecalltoaction" class="block block--block-contenta8a59224-4648-42d5-b71c-294b3c630d8a block-sitecalltoaction"> <div class="field field--body"><p>BC Cancer Foundation is the fundraising partner of BC Cancer, which includes BC Cancer Research. 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