Search results for: Abdolamir Gatezadeh

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Gatezadeh</title> <meta name="description" content="Search results for: Abdolamir Gatezadeh"> <meta name="keywords" content="Abdolamir Gatezadeh"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Abdolamir Gatezadeh"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 4</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Abdolamir Gatezadeh</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> The Relationship between the Personality Traits and Self-Compassion with Psychological Well-Being in Iranian College Students</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdolamir%20Gatezadeh">Abdolamir Gatezadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Rezvan%20K.%20A.%20Mohamamdi"> Rezvan K. A. Mohamamdi</a>, <a href="https://publications.waset.org/abstracts/search?q=Arash%20Jelodari"> Arash Jelodari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It has been well established that personality traits and self-compassion are associated with psychological well-being. Thus, the current research aimed to investigate the underlying mechanisms in a collectivist culture. Method: One hundred and fifty college students were chosen and filled out Ryff's Psychological Well-Being Scale, the NEO Personality Inventory, and Neff's Self-Compassion Scale. Results: The results of correlation analysis showed that there were significant relationships between the personality traits (neuroticism, extraversion, agreeableness, and conscientiousness) and self-compassion (self-kindness, isolation, mindfulness, and the total score of self-compassion) with psychological well-being. The regression analysis showed that neuroticism, extraversion, and conscientiousness significantly predicted psychological well-being. Discussion and conclusion: The cultural implications and future orientations have been discussed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=college%20students" title="college students">college students</a>, <a href="https://publications.waset.org/abstracts/search?q=personality%20traits" title=" personality traits"> personality traits</a>, <a href="https://publications.waset.org/abstracts/search?q=psychological%20well-being" title=" psychological well-being"> psychological well-being</a>, <a href="https://publications.waset.org/abstracts/search?q=self-compassion" title=" self-compassion"> self-compassion</a> </p> <a href="https://publications.waset.org/abstracts/90419/the-relationship-between-the-personality-traits-and-self-compassion-with-psychological-well-being-in-iranian-college-students" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90419.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">216</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Testing Causal Model of Depression Based on the Components of Subscales Lifestyle with Mediation of Social Health</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdolamir%20Gatezadeh">Abdolamir Gatezadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Jamal%20Daghaleh"> Jamal Daghaleh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The lifestyle of individuals is important and determinant for the status of psychological and social health. Recently, especially in developed countries, the relationship between lifestyle and mental illnesses, including depression, has attracted the attention of many people. In order to test the causal model of depression based on lifestyle with mediation of social health in the study, basic and applied methods were used in terms of objective and descriptive-field as well as the data collection. Methods: This study is a basic research type and is in the framework of correlational plans. In this study, the population includes all adults in Ahwaz city. A randomized, multistage sampling of 384 subjects was selected as the subjects. Accordingly, the data was collected and analyzed using structural equation modeling. Results: In data analysis, path analysis indicated the confirmation of the assumed model fit of research. This means that subscales lifestyle has a direct effect on depression and subscales lifestyle through the mediation of social health which in turn has an indirect effect on depression. Discussion and conclusion: According to the results of the research, the depression can be used to explain the components of the lifestyle and social health. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=depression" title="depression">depression</a>, <a href="https://publications.waset.org/abstracts/search?q=subscales%20lifestyle" title=" subscales lifestyle"> subscales lifestyle</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20health" title=" social health"> social health</a>, <a href="https://publications.waset.org/abstracts/search?q=causal%20model" title=" causal model"> causal model</a> </p> <a href="https://publications.waset.org/abstracts/88579/testing-causal-model-of-depression-based-on-the-components-of-subscales-lifestyle-with-mediation-of-social-health" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/88579.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">163</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Relationship of Epidermal Growth Factor Receptor Gene Mutations Andserum Levels of Ligands in Non-Small Cell Lung Carcinoma Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdolamir%20Allameh">Abdolamir Allameh</a>, <a href="https://publications.waset.org/abstracts/search?q=Seyyed%20Mortaza%20Haghgoo">Seyyed Mortaza Haghgoo</a>, <a href="https://publications.waset.org/abstracts/search?q=Adnan%20Khosravi"> Adnan Khosravi</a>, <a href="https://publications.waset.org/abstracts/search?q=Esmaeil%20Mortaz"> Esmaeil Mortaz</a>, <a href="https://publications.waset.org/abstracts/search?q=Mihan%20Pourabdollah-Toutkaboni"> Mihan Pourabdollah-Toutkaboni</a>, <a href="https://publications.waset.org/abstracts/search?q=Sharareh%20Seifi"> Sharareh Seifi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Non-Small Cell Lung Carcinoma (NSCLC) is associated with a number of gene mutations in epidermal growth factor receptor (EGFR). The prognostic significance of mutations in exons 19 and 21, together with serum levels of EGFR, amphiregulin (AR), and Transforming Growth Factor-alpha (TGF-α) are implicated in diagnosis and treatment. The aim of this study was to examine the relationship of EGFR mutations in selected exons with the expression of relevant ligands in sera samples of NSCLC patients. For this, a group of NSCLC patients (n=98) referred to the hospital for lung surgery with a mean age of 59±10.5 were enrolled (M/F: 75/23). Blood specimen was collected from each patient. Besides, formalin fixed paraffin embedded tissues were processed for DNA extraction. Gene mutations in exons 19 and 21 were detected by direct sequencing, following DNA amplification which was done by PCR (Polymerase Chain Reaction). Also, serum levels of EGFR, AR, and TGF-α were measured by ELISA. The results of our study show that EGFR mutations were present in 37% of Iranian NSCLC patients. The most frequently identified mutations were deletions in exon 19 (72.2%) and substitutions in exon 21 (27.8%). The most frequently identified alteration, which is considered as a rare mutation, was the E872K mutation in exon 21, which was found in 90% (9 out of 10) cases. EGFR mutation detected in exon 21 was significantly (P<0.05) correlated with the levels of its ligands, EGFR and TGF-α in serum samples. Furthermore, it was found that increased serum AR (>3pg/ml) and TGF-α (>10.5 pg/ml) were associated with shorter overall survival (P<0.05). The results clearly showed a close relationship between EGFR mutations and serum EGFR and serum TGF-α. Increased serum EGFR was associated with TGF-α and AR and linked to poor prognosis of NSCLC. These findings are implicated in clinical decision-making related to EGFR-Tyrosine kinase inhibitors (TKIs). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=lung%20cancer" title="lung cancer">lung cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=Iranian%20patients" title=" Iranian patients"> Iranian patients</a>, <a href="https://publications.waset.org/abstracts/search?q=epidermal%20growth%20factor" title=" epidermal growth factor"> epidermal growth factor</a>, <a href="https://publications.waset.org/abstracts/search?q=mutation" title=" mutation"> mutation</a>, <a href="https://publications.waset.org/abstracts/search?q=prognosis" title=" prognosis"> prognosis</a> </p> <a href="https://publications.waset.org/abstracts/141945/relationship-of-epidermal-growth-factor-receptor-gene-mutations-andserum-levels-of-ligands-in-non-small-cell-lung-carcinoma-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141945.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">80</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Oxidative Damage to Lipids, Proteins, and DNA during Differentiation of Mesenchymal Stem Cells Derived from Umbilical Cord into Biologically Active Hepatocytes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdolamir%20Allameh">Abdolamir Allameh</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahnaz%20Esmaeili"> Shahnaz Esmaeili</a>, <a href="https://publications.waset.org/abstracts/search?q=Mina%20Allameh"> Mina Allameh</a>, <a href="https://publications.waset.org/abstracts/search?q=Safoura%20Khajeniazi"> Safoura Khajeniazi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Stem cells with therapeutic applications can be isolated from human placenta/umblical cord blood (UCB) as well as the cord tissue (UC). Stem cells in culture are vulnerable to oxidative stress, particularly when subjected to differentiation process. The aim of this study was to examine the chnages in the rate of oxidation that occurs to cellular macromolecules during hepatic differentiation of mononuclear cells (MSCs). In addition, the impact of the hepatic differentiation process of MSC on cellular and biological activity of the cells will be undertaken. For this purpose, first mononuclear cells (MNCs) were isolated from human UCB which was obtained from a healthy full-term infant. The cells were cultured at a density of 3×10⁵ cells/cm² in DMEM- low-glucose culture media supplemented with 20% FBS, 2 mM L-glutamine, 100 μg/ml streptomycin and 100 U/ml penicillin. Cell cultures were then incubated at 37°C in a humidified 5% CO₂ incubator. After removing non-adherent cells by replacing culture medium, fibroblast-like adherent cells were resuspended in 0.25% trypsin-EDTA and plated in 25 cm² flasks (1×10⁴/ml). Characterization of the MSCs was routinely done by observing their morphology and growth curve. MSCs were subjected to a 2-step hepatocyte differentiation protocol in presence of hepatocyte growth factor (HGF), dexamethazone (DEX) and oncostatin M (OSM). The hepatocyte-like cells derived from MSCs were checked every week for 3 weeks for changes in lipid peroxidation, protein carbonyl formation and DNA oxidation i.e., 8-hydroxy-2'-deoxyguanosine (8-OH-dG) assay. During the 3-week differentiation process of MSCs to hepatocyte-like cells we found that expression liver-specific markers such as albumin, was associated with increased levels of lipid peroxidation and protein carbonyl formation. Whereas, undifferentiated MSCs has relatively low levels of lipid peroxidation products. There was a significant increase ( p < 0.05) in lipid peroxidation products in hepatocytes on days 7, 14, and 21 of differentiation. Likewise, the level of protein carbonyls in the cells was elevated during the differentiation. The level of protein carbonyls measured in hepatocyte-like cells obtained 3 weeks after differentiation induction was estimated to be ~6 fold higher compared to cells recovered on day 7 of differentiation. On the contrary, there was a small but significant decrease in DNA damage marker (8-OH-dG) in hepatocytes recovered 3 weeks after differentiation onset. The level of 8-OHdG which was in consistent with formation of reactive oxygen species (ROS). In conclusion, this data suggest that despite the elevation in oxidation of lipid and protein molecules during hepatocyte development, the cells were normal in terms of DNA integrity, morphology, and biologically activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adult%20stem%20cells" title="adult stem cells">adult stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA%20integrity" title=" DNA integrity"> DNA integrity</a>, <a href="https://publications.waset.org/abstracts/search?q=free%20radicals" title=" free radicals"> free radicals</a>, <a href="https://publications.waset.org/abstracts/search?q=hepatic%20differentiation" title=" hepatic differentiation"> hepatic differentiation</a> </p> <a href="https://publications.waset.org/abstracts/90001/oxidative-damage-to-lipids-proteins-and-dna-during-differentiation-of-mesenchymal-stem-cells-derived-from-umbilical-cord-into-biologically-active-hepatocytes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90001.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">150</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET 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Search results for: Abdolamir Gatezadeh