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Roderic Alfred Gregory - Wikipedia
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<h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Roderic Alfred Gregory</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. 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Society">FRS</a><sup id="cite_ref-frs_1-0" class="reference"><a href="#cite_note-frs-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> (29 December 1913 – 5 September 1990) was a British physiologist. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Early_life_and_career">Early life and career</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Roderic_Alfred_Gregory&action=edit&section=1" title="Edit section: Early life and career"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>He was born in 1913 in <a href="/wiki/Plaistow,_Newham" title="Plaistow, Newham">Plaistow</a>, Essex, the only child of Alfred Gregory and Alice Jane (née Greaves) Gregory. His father was a fitter and turner who, in 1913, was employed by Brunner and Mond (later <a href="/wiki/Imperial_Chemical_Industries" title="Imperial Chemical Industries">Imperial Chemical Industries</a>).<sup id="cite_ref-frs_1-1" class="reference"><a href="#cite_note-frs-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> At the age of 11 he started at the local grammar school, <a href="/wiki/George_Green%27s_School" title="George Green's School">George Green's School</a>.<sup id="cite_ref-frs_1-2" class="reference"><a href="#cite_note-frs-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>He then trained as a physiologist in the Department of Physiology at <a href="/wiki/University_College,_London" class="mw-redirect" title="University College, London">University College</a>, London in the early 1930s and then studied gastrointestinal physiology for a PhD at <a href="/wiki/Northwestern_University" title="Northwestern University">Northwestern University</a>, Illinois. He turned his attention to <a href="/wiki/Gastrin" title="Gastrin">gastrin</a> while he was Holt Professor of Physiology, and Head of Department, at the <a href="/wiki/University_of_Liverpool" title="University of Liverpool">University of Liverpool</a> (appointed in 1948). He "made fundamental contributions to the study of gut hormones through his isolation of the gastric acid stimulating hormone gastrin, the characterisation of its spectrum of actions, the identification of structure-activity relationships and discovery that gastrin was produced in excess in the tumours of patients with <a href="/wiki/Zollinger%E2%80%93Ellison_syndrome" title="Zollinger–Ellison syndrome">Zollinger–Ellison syndrome</a>".<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Much of the work on gastrin at Liverpool was with his long-term collaborator <a href="/wiki/Hilda_Tracy" title="Hilda Tracy">Hilda Tracy</a> in the same department. </p> <div class="mw-heading mw-heading2"><h2 id="Awards_and_recognition">Awards and recognition</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Roderic_Alfred_Gregory&action=edit&section=2" title="Edit section: Awards and recognition"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>He was elected a <a href="/wiki/Fellow_of_the_Royal_Society" title="Fellow of the Royal Society">Fellow of the Royal Society</a> in 1965<sup id="cite_ref-frs_1-3" class="reference"><a href="#cite_note-frs-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> and appointed a <a href="/wiki/Commander_of_the_Order_of_the_British_Empire" class="mw-redirect" title="Commander of the Order of the British Empire">CBE</a> in 1971. He won the <a href="/wiki/Royal_Medal" title="Royal Medal">Royal Medal</a> in 1978.<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Personal_life">Personal life</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Roderic_Alfred_Gregory&action=edit&section=3" title="Edit section: Personal life"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>He married Alice Watts in 1939.<sup id="cite_ref-frs_1-4" class="reference"><a href="#cite_note-frs-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Roderic_Alfred_Gregory&action=edit&section=4" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-frs-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-frs_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-frs_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-frs_1-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-frs_1-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-frs_1-4"><sup><i><b>e</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFDockray1998" class="citation journal cs1">Dockray, G. J. (1998). "Roderic Alfred Gregory, C. B. E.. 29 December 1913 – 5 September 1990". <i><a href="/wiki/Biographical_Memoirs_of_Fellows_of_the_Royal_Society" title="Biographical Memoirs of Fellows of the Royal Society">Biographical Memoirs of Fellows of the Royal Society</a></i>. <b>44</b>: 207–216. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1098%2Frsbm.1998.0014">10.1098/rsbm.1998.0014</a>. <a href="/wiki/JSTOR_(identifier)" class="mw-redirect" title="JSTOR (identifier)">JSTOR</a> <a rel="nofollow" class="external text" href="https://www.jstor.org/stable/770240">770240</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11623981">11623981</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:29047715">29047715</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Biographical+Memoirs+of+Fellows+of+the+Royal+Society&rft.atitle=Roderic+Alfred+Gregory%2C+C.+B.+E..+29+December+1913+%E2%80%93+5+September+1990&rft.volume=44&rft.pages=207-216&rft.date=1998&rft_id=info%3Apmid%2F11623981&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A29047715%23id-name%3DS2CID&rft_id=https%3A%2F%2Fwww.jstor.org%2Fstable%2F770240%23id-name%3DJSTOR&rft_id=info%3Adoi%2F10.1098%2Frsbm.1998.0014&rft.aulast=Dockray&rft.aufirst=G.+J.&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARoderic+Alfred+Gregory" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.regpep-society.com/Rod-Gregory.html">"Winning Method"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Winning+Method&rft_id=http%3A%2F%2Fwww.regpep-society.com%2FRod-Gregory.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARoderic+Alfred+Gregory" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDockrayGregory1980" class="citation journal cs1">Dockray, G. 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J.; <a class="mw-selflink selflink">Gregory, R. A.</a>; Hutchison, J. B.; Harris, J. I.; Runswick, M. J. (1978). 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L.; Beacham, J.; Bentley, P. H.; <a class="mw-selflink selflink">Gregory, R. A.</a>; Kenner, G. W.; Sheppard, R. C.; Tracy, H. J. (1968). "Isolation, structure and synthesis of ovine and bovine gastrins". <i>Nature</i>. <b>219</b> (5154): 614–615. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1968Natur.219..614A">1968Natur.219..614A</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F219614a0">10.1038/219614a0</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/5665711">5665711</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:4267237">4267237</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Isolation%2C+structure+and+synthesis+of+ovine+and+bovine+gastrins&rft.volume=219&rft.issue=5154&rft.pages=614-615&rft.date=1968&rft_id=info%3Adoi%2F10.1038%2F219614a0&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A4267237%23id-name%3DS2CID&rft_id=info%3Apmid%2F5665711&rft_id=info%3Abibcode%2F1968Natur.219..614A&rft.aulast=Agarwal&rft.aufirst=K.+L.&rft.au=Beacham%2C+J.&rft.au=Bentley%2C+P.+H.&rft.au=Gregory%2C+R.+A.&rft.au=Kenner%2C+G.+W.&rft.au=Sheppard%2C+R.+C.&rft.au=Tracy%2C+H.+J.&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARoderic+Alfred+Gregory" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBeachamBentleyGregoryKenner1966" class="citation journal cs1">Beacham, J.; Bentley, P. 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"Physiological Properties of a Series of Synthetic Peptides Structurally Related to Gastrin I". <i>Nature</i>. <b>204</b> (4962): 935–938. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F204935a0">10.1038/204935a0</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/14248713">14248713</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:37773104">37773104</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Physiological+Properties+of+a+Series+of+Synthetic+Peptides+Structurally+Related+to+Gastrin+I&rft.volume=204&rft.issue=4962&rft.pages=935-938&rft.date=1964&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A37773104%23id-name%3DS2CID&rft_id=info%3Apmid%2F14248713&rft_id=info%3Adoi%2F10.1038%2F204935a0&rft.aulast=Tracy&rft.aufirst=H.+J.&rft.au=Gregory%2C+R.+A.&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARoderic+Alfred+Gregory" class="Z3988"></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAndersonBartonGregoryHardy1964" class="citation journal cs1">Anderson, J. C.; Barton, M. A.; <a class="mw-selflink selflink">Gregory, R. A.</a>; Hardy, P. M.; Kenner, G. W.; MacLeod, J. K.; Preston, J.; Sheppard, R. C.; Morley, J. S. (1964). "Synthesis of Gastrin". <i>Nature</i>. <b>204</b> (4962): 933–934. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F204933a0">10.1038/204933a0</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/14248712">14248712</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:40552816">40552816</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Synthesis+of+Gastrin&rft.volume=204&rft.issue=4962&rft.pages=933-934&rft.date=1964&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A40552816%23id-name%3DS2CID&rft_id=info%3Apmid%2F14248712&rft_id=info%3Adoi%2F10.1038%2F204933a0&rft.aulast=Anderson&rft.aufirst=J.+C.&rft.au=Barton%2C+M.+A.&rft.au=Gregory%2C+R.+A.&rft.au=Hardy%2C+P.+M.&rft.au=Kenner%2C+G.+W.&rft.au=MacLeod%2C+J.+K.&rft.au=Preston%2C+J.&rft.au=Sheppard%2C+R.+C.&rft.au=Morley%2C+J.+S.&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARoderic+Alfred+Gregory" class="Z3988"></span></span> </li> <li id="cite_note-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-11">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGregory1946" class="citation journal cs1">Gregory, R. A. (1946). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F157305b0">"Authenticity of scientific anecdotes"</a>. <i>Nature</i>. <b>157</b> (3984): 305. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1946Natur.157..305G">1946Natur.157..305G</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1038%2F157305b0">10.1038/157305b0</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21017938">21017938</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Authenticity+of+scientific+anecdotes&rft.volume=157&rft.issue=3984&rft.pages=305&rft.date=1946&rft_id=info%3Apmid%2F21017938&rft_id=info%3Adoi%2F10.1038%2F157305b0&rft_id=info%3Abibcode%2F1946Natur.157..305G&rft.aulast=Gregory&rft.aufirst=R.+A.&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252F157305b0&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARoderic+Alfred+Gregory" class="Z3988"></span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-12">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.nndb.com/honors/968/000100668/">"Royal Medal"</a><span class="reference-accessdate">. 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