The Global Drug sales of Stelara (2020 - 2026, USD Millions)

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2026, USD Millions)</h3> </div> <div class="cell"> <div class="action-bar graph-bar"> <div class="segment"> <div class="attribute-action social-action align-right"> <div class="social-stack-action-more"> <a class="chunk brand trim clear button rotator" data-toggle="social-media-optionDetailPartial1"> <span>Share</span><i class="gd-ico gd-chevron-down color-border"></i> </a> <div id="social-media-optionDetailPartial1" class="dropdown-pane gutter-collapse " data-v-offset="6" data-close-on-click="true" data-dropdown> <ul id="DDPMenusocial-media-option" class="menu vertical dropdown" data-dropdown-menu data-disable-hover='true' data-click-open='true'> <li> </li> <li> <a onclick="Register()"> <i class="gd-ico gd-contact-linkedin "></i> <span>Share on LinkedIn</span> </a> </li> </ul> </div> </div> </div> </div> <div class="segment"> <a id="GraphBarTableButton001" class="button clear trim" data-toggle="GraphBarTableButton001 GraphBarGraphButton001 GraphBarTable001 GraphBarGraph001" data-toggler="hide"> <i class="gd-ico gd-table color-brand"></i> <span>View as table</span> </a> <a id="GraphBarGraphButton001" class="button clear trim hide" data-toggle="GraphBarTableButton001 GraphBarGraphButton001 GraphBarTable001 GraphBarGraph001" data-toggler="hide"> <i class="gd-ico gd-icon-card-tools color-brand"></i> <span>View as graph</span> </a> </div> </div> <div id="DDPAllDate" class="dropdown-pane gutter-collapse " data-v-offset="6" data-close-on-click="true" data-dropdown> <ul id="DDPMenuDDPAllDate" class="menu vertical dropdown" data-dropdown-menu='' data-disable-hover='true' data-click-open='true'> <li> <a onclick="Register()"> <i class="gd-ico gd-contact-twitter "></i> <span>Share on Twitter</span> </a> </li> <li> <a onclick="Register()"> <i class="gd-ico gd-contact-linkedin "></i> <span>Share on LinkedIn</span> </a> </li> </ul> </div> </div> <div class="cell medium-6 s-large-8 xlarge-9"> <div id="GraphBarTable001" class="hide" data-toggler="hide"> <div class="table-container"> <div class="table-fixedcol tbl-height"> <table class="list-mode compact" id="ValueVolumeHeatGridTable"> </table> </div> </div> </div> <div id="GraphBarGraph001" data-toggler="hide"> <div class="graph-chart "> <div class="chart"> <main id="amchartColumn" class="am-chart ss-medium"></main> <footer> <div class="tagline"></div> <div class="publish">Published: Nov 2024</div> <div class="source">Source: GlobalData</div> </footer> <hr class="foot" /> </div> </div> </div> </div> <div class="cell medium-6 s-large-4 xlarge-3"> <div class="card unlock lock lock-tr"> <a href="/industries-we-cover/globaldata-explorer/"><div class="lock-box"></div></a> <main> <section style="text-align: center; font-weight: 1000"> <span>Unlock Forecasts and Access to 55 Million Statistics for >20 Industries, for $700 a month</span> </section> <section> <div class="button-collection" style="justify-content:center"> <a class="button" href="https://gd-explorer.chargifypay.com/subscribe/26hzbkxhg856"> <span>Buy now</span> </a> <a class="button" href="/industries-we-cover/globaldata-explorer#requestdemo"> <span>Ask for demo</span> </a> </div> </section> </main> </div> </div> <div class="cell section_end"></div> </div> <div class="grid-x grid-margin-x grid-padding-y"> <div class="cell"> <p><p>Ustekinumab (Stelara) is a human monoclonal antibody used as immunosuppressant. It is produced by a recombinant DNA technology. It is formulated as an injectable solution for injection, powder for solution and solution for injection in pre-filled syringe and is administered by subcutaneous route and intravenous administration and injectable concentrate solution for subcutaneous route of administration.</p> <p><strong>Mechanism of Action</strong></p> <p>Ustekinumab is a human IgG1 kappa monoclonal antibody that binds with high affinity and specificity to the IL-12 subunit beta used by both the interleukin (IL)-12 and IL-23 cytokines. In variety of chronic inflammatory conditions IL-12 and IL-23 were implicated to play a role in the initiation of inflammation. p40 subunit is a component of both interleukin-12 (Th1) and interleukin-23 (Th17). Inhibition of the IL-12/23 signaling pathway leads to profound suppression of both the Th1 and Th17 cell lineage of cytokines and chemokines and their inflammatory pathways and thereby elicits the therapeutic intervention.</p> <p><strong>Stelara Overview</strong></p> <p>Stelara is marketed for the treatment of several indications in Cardiovascular, Central Nervous System, Dermatology, Gastrointestinal, Genetic Disorders, Immunology, Metabolic Disorders, and Musculoskeletal Disorders therapy area.</p> <p>Stelara is indicated for the treatment of adult patients (18 years or older) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy, for the treatment of adult patients (18 years or older) with active psoriatic arthritis (PsA), alone or in combination with methotrexate. Stelara is also indicated for the treatment of moderate to severe plaque psoriasis in adolescent patients from the age of 12 years to 17 years, who are inadequately controlled by, or are intolerant to, other systemic therapies or phototherapies, for the treatment of moderately to severely active Crohn’s disease in adults (18 years or older) who have failed or were intolerant to treatment with immunomodulators or corticosteroids but never failed treatment with a tumor necrosis factor (TNF) blocker, or who failed or were intolerant to treatment with one or more TNF blockers, and for the treatment of adult patients with moderately to severely active ulcerative colitis. Stelara is also indicated for the treatment of pediatric patients aged 6 to 11 years with moderate to severe plaque psoriasis. Stelara is also indicated for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a biologic or have medical contraindications to such therapies.</p> <p>Stelara was first approved in 2008 and is sold globally including the US, the UK, France, Germany, and Japan by several pharma giants including <a href="https://www.globaldata.com/company-profile/mitsubishi-chemical-holdings-corp/">Mitsubishi Chemical Holdings Corp</a>, and <a href="https://www.globaldata.com/company-profile/johnson-johnson/">Johnson & Johnson</a>. Stelara drug sales include the historical sales that are derived from company financial reports, and consensus forecasts are calculated based on company-specific broker reports as well as GlobalData’s proprietary methodology.</p></p> </div> </div> <div class="grid-x grid-margin-x grid-padding-y"> <div class="cell"> </div> <div class="cell section_end"></div> </div> </div> <div class="grid-container fluid shade"> <div class="grid-container"> <div class="grid-x grid-margin-x grid-padding-y"> <div class="cell"> <div class="grid-x grid-padding-y grid-margin-x"> <div class="cell large-auto medium-auto auto"><h3>Related Data & Insights</h3></div> </div> <div class="grid-x grid-padding-y grid-margin-x medium-up-3"> <div class="cell"> <div class="card tag"> <main> <section> <a href="/data-insights/healthcare/number-of-ongoing-clinical-trials-for-drugs-involving-acromegaly-by-phase-505009/">Number of ongoing Clinical Trials (for drugs) involving Acromegaly by Phase</a> </section> <section> <div class="button-collection"> <a class="button hollow tag" href="/data-insights/listing/search?location=100006"> <span>Global</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4800069"> <span>Pharmaceuticals</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4800357"> <span>Hormonal Disorders</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4801718"> <span>Therapy Area</span> </a> </div> </section> </main> </div> </div> <div class="cell"> <div class="card tag"> <main> <section> <a href="/data-insights/healthcare/global--five-largest-private-equity-venture-financing-deals-by-value-in-the-pharmaceuticals-sector--ltm-2087924/">Global: Five largest Private Equity/Venture Financing deals by value in the Pharmaceuticals sector (LTM June 2022)</a> </section> <section> <div class="button-collection"> <a class="button hollow tag" href="/data-insights/listing/search?location=100006"> 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class="cell"> <div class="card tag"> <main> <section> <a href="/data-insights/healthcare/number-of-ongoing-clinical-trials-for-drugs-involving-uveal-melanoma-by-phase-503182/">Number of ongoing Clinical Trials (for drugs) involving Uveal Melanoma by Phase</a> </section> <section> <div class="button-collection"> <a class="button hollow tag" href="/data-insights/listing/search?location=100006"> <span>Global</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4800069"> <span>Pharmaceuticals</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4800366"> <span>Oncology</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4801718"> <span>Therapy Area</span> </a> </div> </section> </main> </div> </div> <div class="cell"> <div class="card tag"> <main> <section> <a href="/data-insights/healthcare/number-of-ongoing-clinical-trials-for-drugs-involving-short-bowel-syndrome-by-phase-503110/">Number of ongoing Clinical Trials (for drugs) involving Short Bowel Syndrome by Phase</a> </section> <section> <div class="button-collection"> <a class="button hollow tag" href="/data-insights/listing/search?location=100006"> <span>Global</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4800069"> <span>Pharmaceuticals</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4800353"> <span>Gastrointestinal</span> </a> <a class="button hollow tag" href="/data-insights/listing/search?industry=4801718"> <span>Therapy Area</span> </a> </div> </section> </main> </div> </div> <div class="cell"> <div class="card tag"> <main> <section> <a href="/data-insights/healthcare/global--ltm-partnerships-deal-activity-by-value-and-volume-in-the-pharmaceuticals-sector-2093505/">Global: LTM Partnerships Deal Activity by Value and Volume in the Pharmaceuticals Sector</a> </section> <section> <div class="button-collection"> <a class="button hollow 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The Global Drug sales of Stelara (2020 - 2026, USD Millions) - GlobalData