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<span></span> </div> </a> </div> </div> <section class="info overview _immun"> <div class="overview_body"> <div class="overview_col"> <p class="info_text">The immune system plays a pivotal role in the pathogenesis of many common diseases, including autoimmune and infectious disease, cancer, atherosclerosis and allergies. Along with offering a broad spectrum of disease models and bioassays focused in Immunology and Inflammation, our multidisciplinary scientific team custom-designs each study to expand the capacity of your drug discovery research needs. Interpretive data analysis and a complete raw data set are provided in the final report to accelerate your decision making process.</p> <h2 class="info_title">The Invivotek Immunology and Inflammation Program offers the following models and bioassays:</h2> <h3 class="info_title _secondary">Animal Disease Models</h3> <ul class="list"> <li class="list-item">Antigen-induced Arthritis for Rheumatoid Arthritis</li> <li class="list-item">Collagen-Induced Arthritis for Rheumatoid Arthritis</li> <li class="list-item">Monoclonal Antibody Induced Arthritis for Rheumatoid Arthritis</li> <li class="list-item">Experimental Autoimmune Encephalitis for Multiple Sclerosis</li> <li class="list-item">Allergen-induced Pulmonary Inflammation for Asthma</li> <li class="list-item">Lipopolysaccharides (LPS)-induced Airway Inflammation</li> <li class="list-item">Acute lung injury model (LPS-induced)</li> <li class="list-item">DSS-induced Colitis for Ulcerative Colitis</li> <li class="list-item">TNBS-induced Colitis for Crohn鈥檚 Disease</li> <li class="list-item">Allergic Dermatitis (DNFB or Oxazolone induced)</li> </ul> </div> <div class="overview_col"> <h3 class="info_title _secondary">Non-Disease <em>In vivo</em> Bioassays</h3> <ul class="list"> <li class="list-item">Non-lethal Endotoxemia with LPS</li> <li class="list-item">Antigen-dependent <em>In Vivo</em> T-cell Proliferation by BrdU uptake</li> <li class="list-item">OVA-stimulated <em>In Vivo</em> Antibody Production (IgG1, IgG2a, IgG2b)</li> <li class="list-item">KLH-stimulated <em>In Vivo</em> Antibody Production (IgM, IgG)</li> <li class="list-item">Delayed Type Hypersensitivity by mBSA or KLH with adjuvant</li> <li class="list-item">Delayed Type Hypersensitivity by SRBC</li> <li class="list-item">Monocyte or Neutrophil Infiltration induced by Thioglycollate or Zymosan or Curdlan or Tripsin</li> <li class="list-item">Cutaneous Wound Healing</li> </ul> <h3 class="info_title _secondary">Ex vivo Bioassays</h3> <ul class="list"> <li class="list-item">Serum and Tissue Cytokine Profiling in animal disease models</li> <li class="list-item">FACS Analysis of Lymphoid Organs and Tissue Infiltrates</li> <li class="list-item">Hematology Five Part Differential Cell Count</li> <li class="list-item">Proliferative responses of T and B cells <em>in vitro</em></li> <li class="list-item"><em>In vitro</em> cytokine production assays</li> <li class="list-item">T cell differentiation assay</li> </ul> </div> </div> </section> </div> </section> </main> <div id="modal"> <!--<div id="redirect-modal" class="modal_overlay"> <div class="modal _redirect"> <span class="modal_icon"></span> <p class="modal_text">You are about to be redirected to an external website</p> <div class="modal_row"> <button id="modal-close" class="btn">Cancel</button> <a href="" class="btn _submit">Continue</a> </div> </div> </div>--> <div id="optin-modal" class="modal_overlay"> <div class="modal _optin"> <span class="modal_icon"></span> <p class="modal_text">Before you download, please fill out some info so we can discuss our services with you</p> <div class="modal_body"> <form class="form specific" data-sth="downloads"> <div class="form_msg"> <p class="status">Thank you for your message!</p> </div> <div class="field required"> <input placeholder="Optional" class="if" type="text" name="d_name" required /> <label for="last-name">Name</label> </div> <div class="field required"> <input placeholder="Optional" class="if" type="email" name="d_email" required /> <label for="email">Email</label> </div> <div class="field"> <input placeholder="Optional" class="if" type="number" name="d_phone" /> <label for="phone">Phone</label> </div> <input type="hidden" name="link"> <input type="hidden" name="key_code" value="2c048a9e607c44355c4c85a3ac8c86a0"> <input type="hidden" class="timer" name="timer" value=""> <label style="display: block;height:0;"> <input type="text" name="catch" style="height: 100%; 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