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anhydrase IX</title> <meta name="description" content="Search results for: carbonic anhydrase IX"> <meta name="keywords" content="carbonic anhydrase IX"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="carbonic anhydrase IX"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 22</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: carbonic anhydrase IX</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">22</span> Functional Aspects of Carbonic Anhydrase</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bashistha%20Kumar%20Kanth">Bashistha Kumar Kanth</a>, <a href="https://publications.waset.org/abstracts/search?q=Seung%20Pil%20Pack"> Seung Pil Pack</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Carbonic anhydrase is ubiquitously distributed in organisms, and is fundamental to many eukaryotic biological processes such as photosynthesis, respiration, CO2 and ion transport, calcification and acid–base balance. However, CA occurs across the spectrum of prokaryotic metabolism in both the archaea and bacteria domains and many individual species contain more than one class. In this review, various roles of CA involved in cellular mechanism are presented to find out the CA functions applicable for industrial use. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase" title="carbonic anhydrase">carbonic anhydrase</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanism" title=" mechanism"> mechanism</a>, <a href="https://publications.waset.org/abstracts/search?q=CO2%20sequestration" title=" CO2 sequestration"> CO2 sequestration</a>, <a href="https://publications.waset.org/abstracts/search?q=respiration" title=" respiration"> respiration</a> </p> <a href="https://publications.waset.org/abstracts/1475/functional-aspects-of-carbonic-anhydrase" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1475.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">492</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">21</span> Theoretical Study of Carbonic Anhydrase-Ii Inhibitors for Treatment of Glaucoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=F.%20Boukli%20Hacene">F. Boukli Hacene</a>, <a href="https://publications.waset.org/abstracts/search?q=W.%20Soufi"> W. Soufi</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Ghalem"> S. Ghalem</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Glaucoma disease is a progressive degenerative optic neuropathy, with irreversible visual field deficits and high eye pressure being one of the risk factors. Sulfonamides are carbonic anhydrase-II inhibitors that aim to decrease the secretion of aqueous humor by direct inhibition of this enzyme at the level of the ciliary processes. These drugs present undesirable effects that are difficult to accept by the patient. In our study, we are interested in the inhibition of carbonic anhydrase-II by different natural ligands (curcumin analogues) using molecular modeling methods using molecular operating environment (MOE) software to predict their interaction with this enzyme. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase-II" title="carbonic anhydrase-II">carbonic anhydrase-II</a>, <a href="https://publications.waset.org/abstracts/search?q=curcumin%20analogues" title=" curcumin analogues"> curcumin analogues</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20research" title=" drug research"> drug research</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20modeling" title=" molecular modeling"> molecular modeling</a> </p> <a href="https://publications.waset.org/abstracts/156555/theoretical-study-of-carbonic-anhydrase-ii-inhibitors-for-treatment-of-glaucoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156555.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">89</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> Synthesis and Molecular Docking Studies of Hydrazone Derivatives Potent Inhibitors as a Human Carbonic Anhydrase IX</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sema%20%C5%9Eeno%C4%9Flu">Sema Şenoğlu</a>, <a href="https://publications.waset.org/abstracts/search?q=Sevgi%20Karaku%C5%9F"> Sevgi Karakuş</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hydrazone scaffold is important to design new drug groups and is found to possess numerous uses in pharmaceutical chemistry. Besides, hydrazone derivatives are also known for biological activities such as anticancer, antimicrobial, antiviral, and antifungal. Hydrazone derivatives are promising anticancer agents because they inhibit cancer proliferation and induce apoptosis. Human carbonic anhydrase IX has a high potential to be an antiproliferative drug target, and targeting this protein is also important for obtaining potential anticancer inhibitors. The protein construct was retrieved as a PDB file from the RCSB protein database. This binding interaction of proteins and ligands was performed using Discovery Studio Visualizer. In vitro inhibitory activity of hydrazone derivatives was tested against enzyme carbonic anhydrase IX on the PyRx programme. Most of these molecules showed remarkable human carbonic anhydrase IX inhibitory activity compared to the acetazolamide. As a result, these compounds appear to be a potential target in drug design against human carbonic anhydrase IX. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cancer" title="cancer">cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase%20IX%20enzyme" title=" carbonic anhydrase IX enzyme"> carbonic anhydrase IX enzyme</a>, <a href="https://publications.waset.org/abstracts/search?q=docking" title=" docking"> docking</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrazone" title=" hydrazone"> hydrazone</a> </p> <a href="https://publications.waset.org/abstracts/171356/synthesis-and-molecular-docking-studies-of-hydrazone-derivatives-potent-inhibitors-as-a-human-carbonic-anhydrase-ix" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171356.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">82</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> In vitro Determination of Carbonic Anhydrase Inhibition of the Flowers of Vanda Orchid, Vanda Tessellata Roxb. (1795) by Modified Colorimetric Maren T.H. (1960) Method </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=John%20Carlo%20Combista">John Carlo Combista</a>, <a href="https://publications.waset.org/abstracts/search?q=Jimbert%20Tan"> Jimbert Tan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The orchid, Vanda tessellata was chosen by the researchers because of the presence of the constituents in the family Orchidaceae such as alkaloids, flavonoids and glycosides that might give an inhibition activity of the carbonic anhydrase enzyme. This study aimed to determine the in vitro inhibition of carbonic anhydrase of Vanda tessellata flower extract. With the use of modified colorimetric Maren T.H. (1960) method, the time in seconds each test solution changed its color after the rate of CO2 hydration were recorded. Two solvents were used: the semi-polar, 95% ethanol and the non-polar, dichloromethane solvents. The percent inhibition activity of carbonic anhydrase of the different concentrations of solvents ethanol (1%, 25% and 50%) and dichloromethane (1% and 10%) test solutions were determined. Results showed that the ethanol-based extract of Vanda tessellata in different concentrations showed an inhibitory effect while the dichloromethane-based extract of Vanda tessellata showed no inhibitory effect of carbonic anhydrase activity. For ethanol extract, the concentration with the highest activity was 50% followed by 25% which changed its color from red to yellow with an average time of 13.11 seconds and 11.57 seconds but 1% with an average time of 7.56 seconds did not exhibit an effect. The researchers recommend the isolation of the specific active constituents of Vanda tessellata that is responsible for the inhibitory effect of carbonic anhydrase enzyme. It is also recommended to utilize different blood types to observe different reactions to the inhibition of the carbonic anhydrase. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase" title="carbonic anhydrase">carbonic anhydrase</a>, <a href="https://publications.waset.org/abstracts/search?q=inhibition" title=" inhibition"> inhibition</a>, <a href="https://publications.waset.org/abstracts/search?q=modified%20colorimetric%20Maren%20TH%20method" title=" modified colorimetric Maren TH method"> modified colorimetric Maren TH method</a>, <a href="https://publications.waset.org/abstracts/search?q=Vanda%20orchid" title=" Vanda orchid"> Vanda orchid</a> </p> <a href="https://publications.waset.org/abstracts/78563/in-vitro-determination-of-carbonic-anhydrase-inhibition-of-the-flowers-of-vanda-orchid-vanda-tessellata-roxb-1795-by-modified-colorimetric-maren-th-1960-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/78563.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">298</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> Ergosterol Regulated Functioning of Rubisco in Tomato</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Prabir%20Kumar%20Paul">Prabir Kumar Paul</a>, <a href="https://publications.waset.org/abstracts/search?q=Joyeeta%20Mitra"> Joyeeta Mitra</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ergosterol, is an important fungal metabolite on phylloplane which is not synthesised by plants. However, the functional requirement of ergosterol to the plants is still an enigma. Being ubiquitously present in all plants except algae needs an insight into its physiological implication. The present study aimed at understanding if and how ergosterol influences the physiology of chloroplast particularly the activity of RuBisCo and carbonic anhydrase. The concept of the study was based on one of our earlier observation of enhanced Hills reaction in plants treated with fungal metabolites which contained ergosterol. The fungal metabolite treated plants had a significantly high concentration of photosynthetic pigments. Eight-week-old tomato plants raised under aseptic conditions at 25 + 10 C, 75 % relative humidity and 12 hour L/D photoperiod. Metabolites of Aspergillus niger and Fusarium oxysporum were sprayed on plants either singly or in a 1: 1 combination. A separate group of plants was also treated with 0.5, 1.0, 3.0, 5.0. 7.0 mg ergosterol / ml of n- heptane. Control plants were treated with sterile distilled water only. Plants were sampled at 24, 48, 72 and 96 hours of treatment. RuBisCo and carbonic anhydrase was estimated from sampled leaves. RuBisCo was separated on 1D SDS-PAGE and subjected to MALDI – TOF- TOF – MS analysis. The presence of ergosterol in fungal metabolites was confirmed. Fungal metabolites significantly enhanced the concentration and activity of RuBisCo and carbonic anhydrase. The Vmax activity of the enzymes was significantly high in metabolite treated plants. 1:1 mix of metabolite was more effective than when applied individually. Insilico analysis revealed, RuBisCo subunits had a binding site for ergosterol and in its presence affinity of Co2 to the enzyme increased by several folds. Invivo activity of RuBisCo was significantly elicited by ergosterol. Results of the present study indicate that ergosterol from phylloplane microfungi probably regulates the binding of Co2 to RuBisCo along with activity of carbonic anhydrase thereby modulating the physiology of choloroplast. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase" title="carbonic anhydrase">carbonic anhydrase</a>, <a href="https://publications.waset.org/abstracts/search?q=ergosterol" title=" ergosterol"> ergosterol</a>, <a href="https://publications.waset.org/abstracts/search?q=phylloplane" title=" phylloplane"> phylloplane</a>, <a href="https://publications.waset.org/abstracts/search?q=RuBisCo" title=" RuBisCo"> RuBisCo</a> </p> <a href="https://publications.waset.org/abstracts/60882/ergosterol-regulated-functioning-of-rubisco-in-tomato" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60882.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">235</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Expression of Hypoxia-Inducible Transmembrane Carbonic Anhydrases IX, Ca XII and Glut 1 in Ovarian Cancer </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Sunitha">M. Sunitha</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20Nithyavani"> B. Nithyavani</a>, <a href="https://publications.waset.org/abstracts/search?q=Mathew%20Yohannan"> Mathew Yohannan</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Thiruvieni%20Balajji"> S. Thiruvieni Balajji</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Rathi"> M. A. Rathi</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Arul%20Raj"> C. Arul Raj</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Ragavendran"> P. Ragavendran</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20K.%20Gopalkrishnan"> V. K. Gopalkrishnan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Establishment of an early and reliable biomarker for ovarian carcinogenesis whose expression can be monitored through noninvasive techniques will enable early diagnosis of cancer. Carbonic anhydrases (CA) isozymes IX and XII have been suggested to play a role in oncogenic processes. In von Hippel-Lindau (VHL)-defective tumors, the cell surface transmembrane carbonic anhydrase (CA) CA XI and CA XII genes are overexpressed because of the absence of pVHL. These enzymes are involved in causing a hypoxia condition, thereby providing an environment for metastasis. Aberrant expression of the facilitative glucose transporter GLUT I is found in a wide spectrum of epithelial malignancies. Studying the mRNA expression of CA IX, CA XII and Glut I isozymes in ovarian cancer cell lines (OAW-42 and PA-1) revealed the expression of these hypoxia genes. Immunohistochemical staining of carbonic anhydrases was also performed in 40 ovarian cancer tissues. CA IX and CA XII were expressed at 540 bp and 520 bp in OAW42, PA1 in ovarian cancer cell lines. GLUT-1 was expressed at 325bp in OAW 42, PA1 genes in ovarian cancer cell lines. Immunohistochemistry revealed high to moderate levels of expression of these enzymes. The immuostaining was seen predominantly on the cell surface membrane. The study concluded that these genes CA IX, CA XII and Glut I are expressed under hypoxic condition in tumor cells. From the present results expression of CA IX, XII and Glut I may represent potential targets in ovarian cancer therapy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ovarian%20cancer" title="ovarian cancer">ovarian cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase%20IX" title=" carbonic anhydrase IX"> carbonic anhydrase IX</a>, <a href="https://publications.waset.org/abstracts/search?q=XII" title=" XII"> XII</a>, <a href="https://publications.waset.org/abstracts/search?q=Glut%20I" title=" Glut I"> Glut I</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor%20markers" title=" tumor markers "> tumor markers </a> </p> <a href="https://publications.waset.org/abstracts/9998/expression-of-hypoxia-inducible-transmembrane-carbonic-anhydrases-ix-ca-xii-and-glut-1-in-ovarian-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9998.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">369</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> A Density Functional Theory Study of Metal-Porphyrin Graphene for CO2 Hydration</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manju%20Verma">Manju Verma</a>, <a href="https://publications.waset.org/abstracts/search?q=Parag%20A.%20Deshpande"> Parag A. Deshpande</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Electronic structure calculations of hydrogen terminated metal-porphyrin graphene were carried out to explore the catalytic activity for CO2 hydration reaction. A ruthenium atom was substituted in place of carbon atom of graphene and ruthenium chelated carbon atoms were replaced by four nitrogen atoms in metal-porphyrin graphene system. Ruthenium atom created the active site for CO2 hydration reaction. Ruthenium-porphyrin graphene followed the mechanism of carbonic anhydrase enzyme for CO2 conversion to HCO3- ion. CO2 hydration reaction over ruthenium-porphyrin graphene proceeded via the elementary steps: OH- formation from H2O dissociation, CO2 bending in presence of nucleophilic attack of OH- ion, HCO3- ion formation from proton migration, HCO3- ion desorption by H2O addition. Proton transfer to yield HCO3- ion was observed as a rate limiting step from free energy landscape. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ruthenium-porphyrin%20graphene" title="ruthenium-porphyrin graphene">ruthenium-porphyrin graphene</a>, <a href="https://publications.waset.org/abstracts/search?q=CO2%20hydration" title=" CO2 hydration"> CO2 hydration</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase" title=" carbonic anhydrase"> carbonic anhydrase</a>, <a href="https://publications.waset.org/abstracts/search?q=heterogeneous%20catalyst" title=" heterogeneous catalyst"> heterogeneous catalyst</a>, <a href="https://publications.waset.org/abstracts/search?q=density%20functional%20theory" title=" density functional theory"> density functional theory</a> </p> <a href="https://publications.waset.org/abstracts/60222/a-density-functional-theory-study-of-metal-porphyrin-graphene-for-co2-hydration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60222.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">260</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Novel Bioinspired Design to Capture Smoky CO2 by Reactive Absorption with Aqueous Scrubber</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20E.%20O.%20Hernandez">J. E. O. Hernandez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the next 20 years, energy production by burning fuels will increase and so will the atmospheric concentration of CO2 and its well-known threats to life on Earth. The technologies available for capturing CO2 are still dubious and this keeps fostering an interest in bio-inspired approaches. The leading one is the application of carbonic anhydrase (CA) –a superfast biocatalyst able to convert up to one million molecules of CO2 into carbonates in water. However, natural CA underperforms when applied to real smoky CO2 in chimneys and, so far, the efforts to create superior CAs in the lab rely on screening methods running under pristine conditions at the micro level, which are far from resembling those in chimneys. For the evolution of man-made enzymes, selection rather than screening would be ideal but this is challenging because of the need for a suitable artificial environment that is also sustainable for our society. Herein we present the stepwise design and construction of a bioprocess (from bench-scale to semi-pilot) for evolutionary selection experiments. In this bioprocess, reaction and adsorption took place simultaneously at atmospheric pressure in a spray tower. The scrubbing solution was fed countercurrently by reusing municipal pressure and it was mainly prepared with water, carbonic anhydrase and calcium chloride. This bioprocess allowed for the enzymatic carbonation of smoky CO2; the reuse of process water and the recovery of solid carbonates without cooling of smoke, pretreatments, solvent amines and compression of CO2. The average yield of solid carbonates was 0.54 g min-1 or 12-fold the amount produced in serum bottles at lab bench scale. This bioprocess could be used as a tailor-made environment for driving the selection of superior CAs. The bioprocess and its match CA could be sustainably used to reduce global warming by CO2 emissions from exhausts. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biological%20carbon%20capture%20and%20sequestration" title="biological carbon capture and sequestration">biological carbon capture and sequestration</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrase" title=" carbonic anhydrase"> carbonic anhydrase</a>, <a href="https://publications.waset.org/abstracts/search?q=directed%20evolution" title=" directed evolution"> directed evolution</a>, <a href="https://publications.waset.org/abstracts/search?q=global%20warming" title=" global warming"> global warming</a> </p> <a href="https://publications.waset.org/abstracts/43330/novel-bioinspired-design-to-capture-smoky-co2-by-reactive-absorption-with-aqueous-scrubber" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43330.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">193</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Screening of Phytochemicals Compounds from Chasmanthera dependens and Carissa edulis as Potential Inhibitors of Carbonic Anhydrases CA II (3HS4) Receptor using a Target-Based Drug Design</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Owonikoko%20Abayomi%20Dele">Owonikoko Abayomi Dele</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Epilepsy is an unresolved disease that needs urgent attention. It is a brain disorder that affects over sixty-five (65) million people around the globe. Despite the availability of commercial anti-epileptic drugs, the war against this unmet condition is yet to be resolved. Most epilepsy patients are resistant to available anti-epileptic medications thus the need for affordable novel therapy against epilepsy is a necessity. Numerous phytochemicals have been reported for their potency, efficacy and safety as therapeutic agents against many diseases. This study investigated 99 isolated phytochemicals from Chasmanthera dependens and Carissa edulis against carbonic anhydrase (ii) drug target. The absorption, distribution, metabolism, excretion and toxicity (ADMET) of the isolated compounds were examined using admet SAR-2 web server while Swiss ADME was used to analyze the oral bioavailability, drug-likeness and lead-likeness properties of the selected leads. PASS web server was used to predict the biological activities of selected leads while other important physicochemical properties and interactions of the selected leads with the active site of the target after successful molecular docking simulation with the pyrx virtual screening tool were also examined. The results of these study identified seven lead compounds; C49- alpha-carissanol (-7.6 kcal/mol), C13- Catechin (-7.4 kcal/mol), C45- Salicin (-7.4 kcal/mol), C6- Bisnorargemonine (-7.3 kcal/mol), C36- Pallidine (-7.1 kcal/mol), S4- Lacosamide (-7.1 kcal/mol), and S7- Acetazolamide (-6.4 kcal/mol) for CA II (3HS4 receptor). These leads compounds are probable inhibitors of this drug target due to the observed good binding affinities and favourable interactions with the active site of the drug target, excellent ADMET profiles, PASS Properties, drug-likeness, lead-likeness and oral bioavailability properties. The identified leads have better binding energies as compared to the binding energies of the two standards. Thus, seven identified lead compounds can be developed further towards the development of new anti-epileptic medications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=drug-likeness" title="drug-likeness">drug-likeness</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemicals" title=" phytochemicals"> phytochemicals</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonic%20anhydrases" title=" carbonic anhydrases"> carbonic anhydrases</a>, <a href="https://publications.waset.org/abstracts/search?q=metalloeazymes" title=" metalloeazymes"> metalloeazymes</a>, <a href="https://publications.waset.org/abstracts/search?q=active%20site" title=" active site"> active site</a>, <a href="https://publications.waset.org/abstracts/search?q=ADMET" title=" ADMET"> ADMET</a> </p> <a href="https://publications.waset.org/abstracts/186547/screening-of-phytochemicals-compounds-from-chasmanthera-dependens-and-carissa-edulis-as-potential-inhibitors-of-carbonic-anhydrases-ca-ii-3hs4-receptor-using-a-target-based-drug-design" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/186547.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">56</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Screening of Nickel-Tolerant Genotype of Mung Bean (Vigna radiata) Based on Photosynthesis and Antioxidant System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Yusuf">Mohammad Yusuf</a>, <a href="https://publications.waset.org/abstracts/search?q=Qazi%20Fariduddin"> Qazi Fariduddin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The main aim of this study was to explore the different cultivars of Vigna radiata on basis of photosynthesis, antioxidants and proline to assess Ni-sensitive and Ni-tolerant cultivar. Seeds of five different cultivars were sown in soil amended with different levels of Ni (0, 50, 100, or 150 mg kg 1). At 30 d stage, plants were harvested to assess the various parameters. The Ni treatment diminished growth, leaf water potential, chlorophyll content and net photosynthesis along with nitrate reductase and carbonic anhydrase activities in the concentration dependent manner whereas, it enhanced proline content and various antioxidant enzymes. The varieties T-44 found least affected, whereas PDM-139 experienced maximum damage at 150 mg kg-1 of Ni. Moreover, T-44 possessed maximum activity of antioxidant enzymes and proline content at all the levels of metal whereas PDM-139 possessed minimum values. Therefore, T-44 and PDM-139 were established as the most resistant and sensitive varieties, respectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vigna%20radiata" title="Vigna radiata">Vigna radiata</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidants" title=" antioxidants"> antioxidants</a>, <a href="https://publications.waset.org/abstracts/search?q=nickel" title=" nickel"> nickel</a>, <a href="https://publications.waset.org/abstracts/search?q=photosynthesis" title=" photosynthesis"> photosynthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=proline" title=" proline"> proline</a> </p> <a href="https://publications.waset.org/abstracts/41897/screening-of-nickel-tolerant-genotype-of-mung-bean-vigna-radiata-based-on-photosynthesis-and-antioxidant-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41897.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">223</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Quantified Metabolomics for the Determination of Phenotypes and Biomarkers across Species in Health and Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Miroslava%20Cuperlovic-Culf">Miroslava Cuperlovic-Culf</a>, <a href="https://publications.waset.org/abstracts/search?q=Lipu%20Wang"> Lipu Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Ketty%20Boyle"> Ketty Boyle</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadine%20Makley"> Nadine Makley</a>, <a href="https://publications.waset.org/abstracts/search?q=Ian%20Burton"> Ian Burton</a>, <a href="https://publications.waset.org/abstracts/search?q=Anissa%20Belkaid"> Anissa Belkaid</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Touaibia"> Mohamed Touaibia</a>, <a href="https://publications.waset.org/abstracts/search?q=Marc%20E.%20Surrette"> Marc E. Surrette </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Metabolic changes are one of the major factors in the development of a variety of diseases in various species. Metabolism of agricultural plants is altered the following infection with pathogens sometimes contributing to resistance. At the same time, pathogens use metabolites for infection and progression. In humans, metabolism is a hallmark of cancer development for example. Quantified metabolomics data combined with other omics or clinical data and analyzed using various unsupervised and supervised methods can lead to better diagnosis and prognosis. It can also provide information about resistance as well as contribute knowledge of compounds significant for disease progression or prevention. In this work, different methods for metabolomics quantification and analysis from Nuclear Magnetic Resonance (NMR) measurements that are used for investigation of disease development in wheat and human cells will be presented. One-dimensional 1H NMR spectra are used extensively for metabolic profiling due to their high reliability, wide range of applicability, speed, trivial sample preparation and low cost. This presentation will describe a new method for metabolite quantification from NMR data that combines alignment of spectra of standards to sample spectra followed by multivariate linear regression optimization of spectra of assigned metabolites to samples’ spectra. Several different alignment methods were tested and multivariate linear regression result has been compared with other quantification methods. Quantified metabolomics data can be analyzed in the variety of ways and we will present different clustering methods used for phenotype determination, network analysis providing knowledge about the relationships between metabolites through metabolic network as well as biomarker selection providing novel markers. These analysis methods have been utilized for the investigation of fusarium head blight resistance in wheat cultivars as well as analysis of the effect of estrogen receptor and carbonic anhydrase activation and inhibition on breast cancer cell metabolism. Metabolic changes in spikelet’s of wheat cultivars FL62R1, Stettler, MuchMore and Sumai3 following fusarium graminearum infection were explored. Extensive 1D 1H and 2D NMR measurements provided information for detailed metabolite assignment and quantification leading to possible metabolic markers discriminating resistance level in wheat subtypes. Quantification data is compared to results obtained using other published methods. Fusarium infection induced metabolic changes in different wheat varieties are discussed in the context of metabolic network and resistance. Quantitative metabolomics has been used for the investigation of the effect of targeted enzyme inhibition in cancer. In this work, the effect of 17 β -estradiol and ferulic acid on metabolism of ER+ breast cancer cells has been compared to their effect on ER- control cells. The effect of the inhibitors of carbonic anhydrase on the observed metabolic changes resulting from ER activation has also been determined. Metabolic profiles were studied using 1D and 2D metabolomic NMR experiments, combined with the identification and quantification of metabolites, and the annotation of the results is provided in the context of biochemical pathways. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=metabolic%20biomarkers" title="metabolic biomarkers">metabolic biomarkers</a>, <a href="https://publications.waset.org/abstracts/search?q=metabolic%20network" title=" metabolic network"> metabolic network</a>, <a href="https://publications.waset.org/abstracts/search?q=metabolomics" title=" metabolomics"> metabolomics</a>, <a href="https://publications.waset.org/abstracts/search?q=multivariate%20linear%20regression" title=" multivariate linear regression"> multivariate linear regression</a>, <a href="https://publications.waset.org/abstracts/search?q=NMR%20quantification" title=" NMR quantification"> NMR quantification</a>, <a href="https://publications.waset.org/abstracts/search?q=quantified%20metabolomics" title=" quantified metabolomics"> quantified metabolomics</a>, <a href="https://publications.waset.org/abstracts/search?q=spectral%20alignment" title=" spectral alignment"> spectral alignment</a> </p> <a href="https://publications.waset.org/abstracts/46114/quantified-metabolomics-for-the-determination-of-phenotypes-and-biomarkers-across-species-in-health-and-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46114.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">338</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Improving the Growth, Biochemical Parameters and Content and Composition of Essential Oil of Mentha piperita L. through Soil-Applied N, P, and K </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bilal%20Bhat">Bilal Bhat</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Masroor%20A.%20Khan"> M. Masroor A. Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Moin%20Uddin"> Moin Uddin</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Naeem"> M. Naeem</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aromatic herb, peppermint (Mentha piperita L.), is a natural hybrid (M. aquatica × M. spicata) with immense therapeutic uses, apart from other potential uses. Peppermint oil is one of the most popular and widely used essential oil (EO), because of its main components menthol and menthone. In view of enhancing growth, yield and quality of this medicinally important herb, a pot experiment was conducted in the net-house of the department. The experiment was aimed at studying the effect of graded levels of N, P, and K on growth, biochemical characteristics, and content and composition of EO in Mentha piperita L. Six NPK treatments (viz. N0P0K0, N20P20K20, N40P40K40, N20+20 P20+20 K20+20, N60P60K60, and N30+30 P30+30 K30+30) were tested. The plants were harvested 150 days after transplanting. The crop performance was assessed in terms of growth attributes, physiological activities, herbage yield and content as well as yield of active constituents of Mentha piperita L. Biochemical parameters were analyzed spectrophotometrically. The EO was extracted using Clevenger’s apparatus and the active constituents of the oil were determined using Gas Chromatography. Split-dose application of N, P and K (N30+30 P30+30 K30+30) ameliorated most of the parameters significantly including, fresh and dry weight of plant, NPK content, chlorophyll and carotenoids content, and the activities of carbonic anhydrase and nitrate reductase in the leaves. It also enhanced the EO content (44.0%), EO yield (91.0%), menthol content (14.1%), menthone content (34.0%), menthyl acetate content (16.9%) and 1, 8-cineole content (43.7%) but decreased the pulegone content (36.8%). Conclusively, the fertilization proved useful in enhancing the EO content, yield and other EO components of the plant. Thus, the yield and quality of EO of peppermint may be improved by this agricultural strategy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mentha%20piperita" title="mentha piperita">mentha piperita</a>, <a href="https://publications.waset.org/abstracts/search?q=menthol" title=" menthol"> menthol</a>, <a href="https://publications.waset.org/abstracts/search?q=menthone" title=" menthone"> menthone</a>, <a href="https://publications.waset.org/abstracts/search?q=EO" title=" EO"> EO</a> </p> <a href="https://publications.waset.org/abstracts/11602/improving-the-growth-biochemical-parameters-and-content-and-composition-of-essential-oil-of-mentha-piperita-l-through-soil-applied-n-p-and-k" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11602.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">498</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Contribution of the Study of Inclusion Fluids to the Knowledge of the Conditions of Formation of the Layers with SN-W of Central Hoggar, Algeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20Bouguebrine">J. Bouguebrine</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Bouabsa"> L. Bouabsa </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The ground of study is localized in central Hoggar and contains the most important layers and Stanno-Wolframifére indices of the metallogenic province have tin and wolfram of Hoggar. These layers are always associate with post-orogenetic Panafrican magmatism (GMR) which was set up in the form of circumscribed granitic solid masses of relatively reduced size or in dykes of microgranites. The area studied are in Tounine, Aléméda, Hanana-hananére, Tim Amzi, El Karoussa. The geochemical data processing watch peralumineux character rich person out of Li-F and rare metals (MR). Pegmatites of the type stocksheider, formations of greisens and mineralization Sn-W accompany these granites. Mineralisation Sn-W, expressed particularly well in the seams of quartz and greinsen is spacialement and génitiquement dependent on the maguatism specific to white feldspar-topaz (GMR) (grained and microgrenu). the mineral paragenesis is primarily made up of wolframite and cassetérite. The minerals of gangue are represented by quartz, topaz, the micas containing lithia and the fluorite. A microthermometric study of fluid inclusions related to the granites end on white feldspar-topaz of Hanana, topaz of Hananére, the microgranite of Aléméda, and the seams of quartz D In Tounine (Tiftazouine) and of Tim Amzi; allows to characterize the fluids associated with these layers. It comes out from this study the abundance of aqueous inclusions and three types of fluids were given: -Hot and salted fluids rich in volatile elements particularly CO2; -follow-ups by aquo-carbonic fluids less hot and moderately salted with temperatures of homogenisations (HT) average respectively of 300°C and 180°C; -finally of the aqueous fluids very little salted (≤1%pds.éq.NaCl) and definitely colder. An estimate depths éteé made starting from the diagram of (Haas, 1971) in the system H2O-NaCl, the results are the following: • Inclusion aqueous (L and Lw): correspond to depths of about 50 à500m. • Inclusions aquo-carbonic (Lcw and Lwc): correspond to depths of L order of 600 with 1200m • Carbonic inclusion (Vcw): correspond to depths about 1400à1800m <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fluid%20inclusions%20microthermom%C3%A9trie" title="fluid inclusions microthermométrie">fluid inclusions microthermométrie</a>, <a href="https://publications.waset.org/abstracts/search?q=cassiterite%20wolframite" title=" cassiterite wolframite"> cassiterite wolframite</a>, <a href="https://publications.waset.org/abstracts/search?q=granites%20with%20rare%20metals" title=" granites with rare metals"> granites with rare metals</a>, <a href="https://publications.waset.org/abstracts/search?q=Central%20Hoggar" title=" Central Hoggar"> Central Hoggar</a> </p> <a href="https://publications.waset.org/abstracts/24939/contribution-of-the-study-of-inclusion-fluids-to-the-knowledge-of-the-conditions-of-formation-of-the-layers-with-sn-w-of-central-hoggar-algeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24939.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">405</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Study of Coconut and Babassu Oils with High Acid Content and the Fatty Acids (C6 to C16) Obtained from These Oils</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fl%C3%A1vio%20A.%20F.%20da%20Ponte">Flávio A. F. da Ponte</a>, <a href="https://publications.waset.org/abstracts/search?q=Jackson%20Q.%20Malveira"> Jackson Q. Malveira</a>, <a href="https://publications.waset.org/abstracts/search?q=Jos%C3%A9%20%20A.%20S.%20Ramos%20Filho"> José A. S. Ramos Filho</a>, <a href="https://publications.waset.org/abstracts/search?q=Monica%20C.%20G.%20Albuquerque"> Monica C. G. Albuquerque</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The vegetable oils have many applications in industrial processes and due to this potential have constantly increased the demand for the use of low-quality oils, mainly in the production of biofuel. This work aims to the physicochemical evaluation of babassu oil (Orbinya speciosa) and coconut (Cocos nucifera) of low quality, as well the obtaining the free fatty acids 6 to 16 carbon atoms, with intention to be used as raw material for the biofuels production. The babassu oil and coconut low quality, as well the fatty acids obtained from these oils were characterized as their physicochemical properties and fatty acid composition (using gas chromatography coupled to mass). The NMR technique was used to assess the efficiency of fractional distillation under reduced pressure to obtain the intermediate carbonic chain fatty acids. The results showed that the bad quality in terms of physicochemical evaluation of babassu oils and coconut oils interfere directly in industrial application. However the fatty acids of intermediate carbonic chain (C6 to C16) may be used in cosmetic, pharmaceutical and particularly as the biokerosene fuel. The chromatographic analysis showed that the babassu oil and coconut oil have as major fatty acids are lauric acid (57.5 and 38.6%, respectively), whereas the top phase from distillation of coconut oil showed caprylic acid (39.1%) and major fatty acid. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=babassu%20oil%20%28Orbinya%20speciosa%29" title="babassu oil (Orbinya speciosa)">babassu oil (Orbinya speciosa)</a>, <a href="https://publications.waset.org/abstracts/search?q=coconut%20oil%20%28Cocos%20nucifera%29" title=" coconut oil (Cocos nucifera)"> coconut oil (Cocos nucifera)</a>, <a href="https://publications.waset.org/abstracts/search?q=fatty%20acids" title=" fatty acids"> fatty acids</a>, <a href="https://publications.waset.org/abstracts/search?q=biomass" title=" biomass"> biomass</a> </p> <a href="https://publications.waset.org/abstracts/48733/study-of-coconut-and-babassu-oils-with-high-acid-content-and-the-fatty-acids-c6-to-c16-obtained-from-these-oils" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48733.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">321</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Improvement in Drying Characteristics of Raisin by Carbonic Maceration– Process Optimization</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nursac%20Akyol">Nursac Akyol</a>, <a href="https://publications.waset.org/abstracts/search?q=Merve%20S.%20Turan"> Merve S. Turan</a>, <a href="https://publications.waset.org/abstracts/search?q=Mustafa%20Ozcelik"> Mustafa Ozcelik</a>, <a href="https://publications.waset.org/abstracts/search?q=Erdogan%20Kucukoner"> Erdogan Kucukoner</a>, <a href="https://publications.waset.org/abstracts/search?q=Erkan%20Karacabey"> Erkan Karacabey</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Traditional raisin production is a long time drying process under sunlight. During this procedure, grapes are open to some environmental effects besides the adverse effects of the long drying period. Thus, there is a need to develop an alternative method being applicable instead of traditional one. To this extent, a combination of a potential pretreatment (carbonic maceration, CM) with convectional oven drying was examined. CM application was used in raisin production (grape drying) as a pretreatment process before oven drying. Pressure, temperature and time were examined as application parameters of CM. In conventional oven drying, the temperature is a process variable. The aim is to find out how CM and convectional drying processes affect the drying characteristics of grapes as well as their physical and chemical properties. For this purpose, the response surface method was used to determine both the effects of the variables and the optimum pretreatment and drying conditions. The optimum conditions of CM for raisin production were 0.3 MPa of pressure value, 4°C of application temperature and 8 hours of application time. The optimized drying temperature was 77°C. The results showed that the application of CM before the drying process improved the drying characteristics. Drying took only 389 minutes for grapes pretreated by CM under optimum conditions and 495 minutes for the control group dried only by the conventional drying process. According to these results, a decrease of 21% was achieved in the time requirement for raisin production. Also, it was observed that the samples dried under optimum conditions had similar physical properties as those the control group had. It was seen that raisin, which was dried under optimum conditions were in better condition in terms of some of the bioactive contents compared to control groups. In light of all results, it is seen that CM has an important potential in the industrial drying of grape samples. The current study was financially supported by TUBITAK, Turkey (Project no: 116R038). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=drying%20time" title="drying time">drying time</a>, <a href="https://publications.waset.org/abstracts/search?q=pretreatment" title=" pretreatment"> pretreatment</a>, <a href="https://publications.waset.org/abstracts/search?q=response%20surface%20methodlogy" title=" response surface methodlogy"> response surface methodlogy</a>, <a href="https://publications.waset.org/abstracts/search?q=total%20phenolic" title=" total phenolic"> total phenolic</a> </p> <a href="https://publications.waset.org/abstracts/118363/improvement-in-drying-characteristics-of-raisin-by-carbonic-maceration-process-optimization" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/118363.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">138</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Foraminiferal Description and Biostratigraphy of Eocene Deposits in Zagros Basin (Izeh and Interior Fars Sub-Basins) in South-West of Iran</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ronak%20Gravand">Ronak Gravand</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Eocene deposits in Zagros basin in tow zones of interior Fars and Izeh include limestone and marly limestone succession along with abundant fossils. The significance of this area is due to its hydro carbonic resources. In Dashte Kuh section, limestone and marly limestone deposits with medium to thick creamy layers containing benthic foraminifera could be seen. Bio-zones identified in such deposits include Opertorbitolites Subzone, Somalina Subzone, Alveolina Nummulites Assemblage Subzone and Nummulites fabianii Silvestriella tetraedra Assembelage Zone. In Nil Kuh section, marly limestone of the succession contain abundant plagic foraminifera. The zones identified in this succession include Morozovella aragonesis Range Zone, Hantkenina nuttalli Range Zone, Hantkenina nuttalli Turborotalia cerro-azulensis Interval Zone, Turborotalia cerro-azulensis Range Zone and Morozovella aragonesis Range Zone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=zagros%20basin" title="zagros basin">zagros basin</a>, <a href="https://publications.waset.org/abstracts/search?q=foraminifera" title=" foraminifera "> foraminifera </a>, <a href="https://publications.waset.org/abstracts/search?q=biozone" title=" biozone"> biozone</a>, <a href="https://publications.waset.org/abstracts/search?q=Iran" title=" Iran"> Iran</a> </p> <a href="https://publications.waset.org/abstracts/12893/foraminiferal-description-and-biostratigraphy-of-eocene-deposits-in-zagros-basin-izeh-and-interior-fars-sub-basins-in-south-west-of-iran" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12893.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">501</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Carbonate Crusts in Jordan: Records of Groundwater Flow, Carbon Fluxes, Tectonic Movement and Climate Change</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nizar%20Abu-Jaber">Nizar Abu-Jaber</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Late Pleistocene and Holocene carbonate crusts in the south of Jordan were studied using a combination of field documentation, petrography, geochemical and isotopic techniques. These surficial crusts and vein deposits appear to have formed as a result of interaction between near-surface groundwater, surficial soil and sediments and rising carbon dioxide. Rising mantle CO2 dissolves in the water to create carbonic acid, which in turn dissolves the calcite in the soil in the sediments. When the pH rises later due to degassing, the carbonate crusts are left in the places where the water was flowing in veins, channels and interfaces between high and low permeability materials. The crusts have the potential for being important records of natural and human agencies on the landscape of the area. They reflect the isotopic composition of the waters in which they precipitated in, and also contain isotopic information about the aeolian calcium fluxes affecting the area (using strontium isotopes). Moreover, changing stream valley base levels can be identified and measured, which can help quantify the rates of tectonic movement. Finally, human activities such and channel construction and terrace building can be identified and traced temporally and spatially using these deposits. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anthropogenic%20change" title="anthropogenic change">anthropogenic change</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonate%20crusts" title=" carbonate crusts"> carbonate crusts</a>, <a href="https://publications.waset.org/abstracts/search?q=environmental%20change" title=" environmental change"> environmental change</a>, <a href="https://publications.waset.org/abstracts/search?q=Jordan" title=" Jordan"> Jordan</a> </p> <a href="https://publications.waset.org/abstracts/60842/carbonate-crusts-in-jordan-records-of-groundwater-flow-carbon-fluxes-tectonic-movement-and-climate-change" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60842.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">279</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Drippers Scaling Inhibition of the Localized Irrigation System by Green Inhibitors Based on Plant Extracts</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Driouiche%20Ali">Driouiche Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Karmal%20Ilham"> Karmal Ilham</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Agadir region is characterized by a dry climate, ranging from arid attenuated by oceanic influences to hyper-arid. The water mobilized in the agricultural sector of greater Agadir is 95% of underground origin and comes from the water table of Chtouka. The rest represents the surface waters of the Youssef Ben Tachfine dam. These waters are intended for the irrigation of 26880 hectares of modern agriculture. More than 120 boreholes and wells are currently exploited. Their depth varies between 10 m and 200 m and the unit flow rates of the boreholes are 5 to 50 l/s. A drop in the level of the water table of about 1.5 m/year, on average, has been observed during the last five years. Farmers are thus called upon to improve irrigation methods. Thus, localized or drip irrigation is adopted to allow rational use of water. The importance of this irrigation system is due to the fact that water is applied directly to the root zone and its compatibility with fertilization. However, this irrigation system faces a thorny problem which is the clogging of pipes and drippers. This leads to a lack of uniformity of irrigation over time. This so-called scaling phenomenon, the consequences of which are harmful (cleaning or replacement of pipes), leads to considerable unproductive expenditure. The objective set by this work is the search for green inhibitors likely to prevent this phenomenon of scaling. This study requires a better knowledge of these waters, their physico-chemical characteristics and their scaling power. Thus, using the "LCGE" controlled degassing technique, we initially evaluated, on pure calco-carbonic water at 30°F, the scaling-inhibiting power of some available plant extracts in our region of Souss-Massa. We then carried out a comparative study of the efficacy of these green inhibitors. The action of the most effective green inhibitor on real agricultural waters was then studied. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=green%20inhibitors" title="green inhibitors">green inhibitors</a>, <a href="https://publications.waset.org/abstracts/search?q=localized%20irrigation" title=" localized irrigation"> localized irrigation</a>, <a href="https://publications.waset.org/abstracts/search?q=plant%20extracts" title=" plant extracts"> plant extracts</a>, <a href="https://publications.waset.org/abstracts/search?q=scaling%20inhibition" title=" scaling inhibition"> scaling inhibition</a> </p> <a href="https://publications.waset.org/abstracts/155083/drippers-scaling-inhibition-of-the-localized-irrigation-system-by-green-inhibitors-based-on-plant-extracts" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/155083.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">82</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Promoting Social Advocacy through Digital Storytelling: The Case of Ocean Acidification</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chun%20Chen%20Yea">Chun Chen Yea</a>, <a href="https://publications.waset.org/abstracts/search?q=Wen%20Huei%20Chou"> Wen Huei Chou</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Many chemical changes in the atmosphere and the ocean are invisible to the naked eye, but they have profound impacts. These changes not only confirm the phenomenon of global carbon pollution, but also forewarn that more changes are coming. The carbon dioxide gases emitted from the burning of fossil fuels dissolve into the ocean and chemically react with seawater to form carbonic acid, which increases the acidity of the originally alkaline seawater. This gradual acidification is occurring at an unprecedented rate and will affect the effective formation of carapace of some marine organisms such as corals and crustaceans, which are almost entirely composed of calcium carbonate. The carapace of these organisms will become more dissoluble. Acidified seawater not only threatens the survival of marine life, but also negatively impacts the global ecosystem via the food chain. Faced with the threat of ocean acidification, all humans are duty-bound. The industrial sector outputs the highest level of carbon dioxide emissions in Taiwan, and the petrochemical industry is the major contributor. Ever since the construction of Formosa Plastics Group's No. 6 Naphtha Cracker Plant in Yunlin County, there have been many environmental concerns such as air pollution and carbon dioxide emission. The marine life along the coast of Yunlin is directly affected by ocean acidification arising from the carbon emissions. Societal change demands our willingness to act, which is what social advocacy promotes. This study uses digital storytelling for social advocacy and ocean acidification as the subject of a visual narrative in visualization to demonstrate the subsequent promotion of social advocacy. Storytelling can transform dull knowledge into an engaging narrative of the crisis faced by marine life. Digital dissemination is an effective social-work practice. The visualization promoting awareness on ocean acidification disseminated via social media platforms, such as Facebook and Instagram. Social media enables users to compose their own messages and share information across different platforms, which helps disseminate the core message of social advocacy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=digital%20storytelling" title="digital storytelling">digital storytelling</a>, <a href="https://publications.waset.org/abstracts/search?q=visualization" title=" visualization"> visualization</a>, <a href="https://publications.waset.org/abstracts/search?q=ocean%20acidification" title=" ocean acidification"> ocean acidification</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20advocacy" title=" social advocacy"> social advocacy</a> </p> <a href="https://publications.waset.org/abstracts/101471/promoting-social-advocacy-through-digital-storytelling-the-case-of-ocean-acidification" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/101471.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">117</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Reactive Transport Modeling in Carbonate Rocks: A Single Pore Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Priyanka%20Agrawal">Priyanka Agrawal</a>, <a href="https://publications.waset.org/abstracts/search?q=Janou%20Koskamp"> Janou Koskamp</a>, <a href="https://publications.waset.org/abstracts/search?q=Amir%20Raoof"> Amir Raoof</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariette%20Wolthers"> Mariette Wolthers</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Calcite is the main mineral found in carbonate rocks, which form significant hydrocarbon reservoirs and subsurface repositories for CO2 sequestration. The injected CO2 mixes with the reservoir fluid and disturbs the geochemical equilibrium, triggering calcite dissolution. Different combinations of fluid chemistry and injection rate may therefore result in different evolution of porosity, permeability and dissolution patterns. To model the changes in porosity and permeability Kozeny-Carman equation K∝〖(∅)〗^n is used, where K is permeability and ∅ is porosity. The value of n is mostly based on experimental data or pore network models. In pore network models, this derivation is based on accuracy of relation used for conductivity and pore volume change. In fact, at a single pore scale, this relationship is the result of the pore shape development due to dissolution. We have prepared a new reactive transport model for a single pore which simulates the complex chemical reaction of carbonic-acid induced calcite dissolution and subsequent pore-geometry evolution at a single pore scale. We use COMSOL Multiphysics package 5.3 for the simulation. COMSOL utilizes the arbitary-Lagrangian Eulerian (ALE) method for the free-moving domain boundary. We examined the effect of flow rate on the evolution of single pore shape profiles due to calcite dissolution. We used three flow rates to cover diffusion dominated and advection-dominated transport regimes. The fluid in diffusion dominated flow (Pe number 0.037 and 0.37) becomes less reactive along the pore length and thus produced non-uniform pore shapes. However, for the advection-dominated flow (Pe number 3.75), the fast velocity of the fluid keeps the fluid relatively more reactive towards the end of the pore length, thus yielding uniform pore shape. Different pore shapes in terms of inlet opening vs overall pore opening will have an impact on the relation between changing volumes and conductivity. We have related the shape of pore with the Pe number which controls the transport regimes. For every Pe number, we have derived the relation between conductivity and porosity. These relations will be used in the pore network model to get the porosity and permeability variation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=single%20pore" title="single pore">single pore</a>, <a href="https://publications.waset.org/abstracts/search?q=reactive%20transport" title=" reactive transport"> reactive transport</a>, <a href="https://publications.waset.org/abstracts/search?q=calcite%20system" title=" calcite system"> calcite system</a>, <a href="https://publications.waset.org/abstracts/search?q=moving%20boundary" title=" moving boundary"> moving boundary</a> </p> <a href="https://publications.waset.org/abstracts/80785/reactive-transport-modeling-in-carbonate-rocks-a-single-pore-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80785.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">374</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Cover Layer Evaluation in Soil Organic Matter of Mixing and Compressed Unsaturated</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nayara%20Torres%20B.%20Acioli">Nayara Torres B. Acioli</a>, <a href="https://publications.waset.org/abstracts/search?q=Jos%C3%A9%20Fernando%20T.%20Juc%C3%A1"> José Fernando T. Jucá</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The uncontrolled emission of gases in urban residues' embankment located near urban areas is a social and environmental problem, common in Brazilian cities. Several environmental impacts in the local and global scope may be generated by atmospheric air contamination by the biogas resulted from the decomposition of solid urban materials. In Brazil, the cities of small size figure mostly with 90% of all cities, with the population smaller than 50,000 inhabitants, according to the 2011 IBGE' census, most of the landfill covering layer is composed of clayey, pure soil. The embankments undertaken with pure soil may reach up to 60% of retention of methane, for the other 40% it may be dispersed into the atmosphere. In face of this figures the oxidative covering layer is granted some space of study, envisaging to reduce this perceptual available in the atmosphere, releasing, in spite of methane, carbonic gas which is almost 20 times as less polluting than Methane. This paper exposes the results of studies on the characteristics of the soil used for the oxidative coverage layer of the experimental embankment of Solid Urban Residues (SUR), built in Muribeca-PE, Brazil, supported of the Group of Solid Residues (GSR), located at Federal University of Pernambuco, through laboratory vacuum experiments (determining the characteristics curve), granularity, and permeability, that in soil with saturation over 85% offers dramatic drops in the test of permeability to the air, by little increments of water, based in the existing Brazilian norm for this procedure. The suction was studied, as in the other tests, from the division of prospection of an oxidative coverage layer of 60cm, in the upper half (0.1 m to 0.3 m) and lower half (0.4 m to 0.6 m). Therefore, the consequences to be presented from the lixiviation of the fine materials after 5 years of finalization of the embankment, what made its permeability increase. Concerning its humidity, it is most retained in the upper part, that comprises the compound, with a difference in the order of 8 percent the superior half to inferior half, retaining the least suction from the surface. These results reveal the efficiency of the oxidative coverage layer in retaining the rain water, it has a lower cost when compared to the other types of layer, offering larger availability of this layer as an alternative for a solution for the appropriate disposal of residues. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=oxidative%20coverage%20layer" title="oxidative coverage layer">oxidative coverage layer</a>, <a href="https://publications.waset.org/abstracts/search?q=permeability" title=" permeability"> permeability</a>, <a href="https://publications.waset.org/abstracts/search?q=suction" title=" suction"> suction</a>, <a href="https://publications.waset.org/abstracts/search?q=saturation" title=" saturation"> saturation</a> </p> <a href="https://publications.waset.org/abstracts/27863/cover-layer-evaluation-in-soil-organic-matter-of-mixing-and-compressed-unsaturated" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27863.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">289</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Discrete Element Simulations of Composite Ceramic Powders </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Julia%20Cristina%20Bonaldo">Julia Cristina Bonaldo</a>, <a href="https://publications.waset.org/abstracts/search?q=Christophe%20L.%20Martin"> Christophe L. Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Severine%20Romero%20Baivier"> Severine Romero Baivier</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephane%20Mazerat"> Stephane Mazerat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Alumina refractories are commonly used in steel and foundry industries. These refractories are prepared through a powder metallurgy route. They are a mixture of hard alumina particles and graphite platelets embedded into a soft carbonic matrix (binder). The powder can be cold pressed isostatically or uniaxially, depending on the application. The compact is then fired to obtain the final product. The quality of the product is governed by the microstructure of the composite and by the process parameters. The compaction behavior and the mechanical properties of the fired product depend greatly on the amount of each phase, on their morphology and on the initial microstructure. In order to better understand the link between these parameters and the macroscopic behavior, we use the Discrete Element Method (DEM) to simulate the compaction process and the fracture behavior of the fired composite. These simulations are coupled with well-designed experiments. Four mixes with various amounts of Al₂O₃ and binder were tested both experimentally and numerically. In DEM, each particle is modelled and the interactions between particles are taken into account through appropriate contact or bonding laws. Here, we model a bimodal mixture of large Al₂O₃ and small Al₂O₃ covered with a soft binder. This composite is itself mixed with graphite platelets. X-ray tomography images are used to analyze the morphologies of the different components. Large Al₂O₃ particles and graphite platelets are modelled in DEM as sets of particles bonded together. The binder is modelled as a soft shell that covers both large and small Al₂O₃ particles. When two particles with binder indent each other, they first interact through this soft shell. Once a critical indentation is reached (towards the end of compaction), hard Al₂O₃ - Al₂O₃ contacts appear. In accordance with experimental data, DEM simulations show that the amount of Al₂O₃ and the amount of binder play a major role for the compaction behavior. The graphite platelets bend and break during the compaction, also contributing to the macroscopic stress. Firing step is modeled in DEM by ascribing bonds to particles which contact each other after compaction. The fracture behavior of the compacted mixture is also simulated and compared with experimental data. Both diametrical tests (Brazilian tests) and triaxial tests are carried out. Again, the link between the amount of Al₂O₃ particles and the fracture behavior is investigated. The methodology described here can be generalized to other particulate materials that are used in the ceramic industry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cold%20compaction" title="cold compaction">cold compaction</a>, <a href="https://publications.waset.org/abstracts/search?q=composites" title=" composites"> composites</a>, <a href="https://publications.waset.org/abstracts/search?q=discrete%20element%20method" title=" discrete element method"> discrete element method</a>, <a href="https://publications.waset.org/abstracts/search?q=refractory%20materials" title=" refractory materials"> refractory materials</a>, <a href="https://publications.waset.org/abstracts/search?q=x-ray%20tomography" title=" x-ray tomography"> x-ray tomography</a> </p> <a href="https://publications.waset.org/abstracts/109186/discrete-element-simulations-of-composite-ceramic-powders" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/109186.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">138</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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