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Michaud</title> <meta name="description" content="Search results for: Aurélie Michaud"> <meta name="keywords" content="Aurélie Michaud"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Aurélie Michaud"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 12</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Aurélie Michaud</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Associations Between Pornography Use Motivations and Sexual Satisfaction in Gender Diverse and Cisgender Individuals in the 43-Country International Sex Survey</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Michaud">Aurélie Michaud</a>, <a href="https://publications.waset.org/abstracts/search?q=%C3%89milie%20Gaudet"> Émilie Gaudet</a>, <a href="https://publications.waset.org/abstracts/search?q=M%C3%B3nika%20Ko%C3%B3s"> Mónika Koós</a>, <a href="https://publications.waset.org/abstracts/search?q=L%C3%A9na%20Nagy"> Léna Nagy</a>, <a href="https://publications.waset.org/abstracts/search?q=Zsolt%20Demetrovics"> Zsolt Demetrovics</a>, <a href="https://publications.waset.org/abstracts/search?q=Shane%20W.%20Kraus"> Shane W. Kraus</a>, <a href="https://publications.waset.org/abstracts/search?q=Marc%20N.%20Potenza"> Marc N. Potenza</a>, <a href="https://publications.waset.org/abstracts/search?q=Be%C3%A1ta%20B%C5%91the"> Beáta Bőthe</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pornography use is prevalent among adults worldwide. Prior studies have assessed the associations between pornography use frequency and sexual satisfaction, in cisgender and heterosexual individuals, with mixed results. However, measuring pornography use solely by pornography use frequency is problematic, as it can lead to disregarding important contextual factors that may be related to pornography use’s potential effects. Pornography use motivations (PUMs) represent key predictors of sexual behaviors. Yet, their associations with different indicators of sexual wellbeing have yet to be extensively studied. This cross-cultural study examined the links between the eight PUMs most often reported in the general population (i.e. sexual pleasure, sexual curiosity, emotional distraction or suppression, fantasy, stress reduction, boredom avoidance, lack of sexual satisfaction, and self-exploration) and sexual satisfaction in gender diverse and cisgender individuals. Given the lack of scientific data on associations between individuals’ PUMs and sexual satisfaction, these links were examined in an exploratory manner. A total of 43 countries from five continents were included in the International Sex Survey (ISS). A secure online platform was used to collect self-report, anonymous data from 82,243 participants (39.6% men, 57% women, 3.4% gender diverse individuals; M = 32.4 years, SD = 12.5). Gender-based differences in levels of sexual pleasure, sexual curiosity, emotional distraction, fantasy, stress reduction, boredom avoidance, lack of sexual satisfaction, and self-exploration PUMs were examined using one-way ANOVAs. Then, for each gender group, the associations between each PUM and sexual satisfaction were examined using multiple linear regression, controlling for frequency of masturbation. One-way ANOVAs indicated significant differences between men, women, and gender diverse individuals on all PUMs. For sexual pleasure, sexual curiosity, fantasy, boredom avoidance, lack of sexual satisfaction, emotional distraction, and stress reduction PUMs, men showed the highest scores, followed by gender-diverse individuals, and women. However, for self-exploration, gender-diverse individuals had higher average scores than men. For all PUMs, women’s average scores were the lowest. After controlling for frequency of masturbation, for all genders, sexual pleasure, sexual curiosity and boredom avoidance were significant positive predictors of sexual satisfaction, while lack of sexual satisfaction PUM was a significant negative predictor. Fantasy, stress reduction and self-exploration PUMs were positive significant predictors of sexual satisfaction, and fantasy was a negative significant predictor, but only for women. Findings highlight important gender differences in regards to the main motivations underlying pornography use and their relations to sexual satisfaction. While men and gender diverse individuals show similar motivation profiles, woman report a particularly unique experience, with fantasy, stress reduction and self-exploration being associated to their sexual satisfaction. This work outlines the importance of considering the role of pornography use motivations when studying the links between pornography viewing and sexual well-being, and may provide basis for gender-based considerations when working with individuals seeking help for their pornography use or sexual satisfaction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pornography" title="pornography">pornography</a>, <a href="https://publications.waset.org/abstracts/search?q=sexual%20satifsaction" title=" sexual satifsaction"> sexual satifsaction</a>, <a href="https://publications.waset.org/abstracts/search?q=cross-cultural" title=" cross-cultural"> cross-cultural</a>, <a href="https://publications.waset.org/abstracts/search?q=gender%20diversity" title=" gender diversity"> gender diversity</a> </p> <a href="https://publications.waset.org/abstracts/159509/associations-between-pornography-use-motivations-and-sexual-satisfaction-in-gender-diverse-and-cisgender-individuals-in-the-43-country-international-sex-survey" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159509.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">106</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Empirical Heat Transfer Correlations of Finned-Tube Heat Exchangers in Pulsatile Flow</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jason%20P.%20Michaud">Jason P. Michaud</a>, <a href="https://publications.waset.org/abstracts/search?q=Connor%20P.%20Speer"> Connor P. Speer</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20A.%20Miller"> David A. Miller</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20S.%20Nobes"> David S. Nobes</a> </p> <p class="card-text"><strong>Abstract:</strong></p> An experimental study on finned-tube radiators has been conducted. Three radiators found in desktop computers sized for 120 mm fans were tested in steady and pulsatile flows of ambient air over a Reynolds number range of  50 < Re < 900. Water at 60 °C was circulated through the radiators to maintain a constant fin temperature during the tests. For steady flow, it was found that the heat transfer rate increased linearly with the mass flow rate of air. The pulsatile flow experiments showed that frequency of pulsation had a negligible effect on the heat transfer rate for the range of frequencies tested (0.5 Hz – 2.5 Hz). For all three radiators, the heat transfer rate was decreased in the case of pulsatile flow. Linear heat transfer correlations for steady and pulsatile flow were calculated in terms of Reynolds number and Nusselt number. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=finned-tube%20heat%20exchangers" title="finned-tube heat exchangers">finned-tube heat exchangers</a>, <a href="https://publications.waset.org/abstracts/search?q=heat%20transfer%20correlations" title=" heat transfer correlations"> heat transfer correlations</a>, <a href="https://publications.waset.org/abstracts/search?q=pulsatile%20flow" title=" pulsatile flow"> pulsatile flow</a>, <a href="https://publications.waset.org/abstracts/search?q=computer%20radiators" title=" computer radiators"> computer radiators</a> </p> <a href="https://publications.waset.org/abstracts/59633/empirical-heat-transfer-correlations-of-finned-tube-heat-exchangers-in-pulsatile-flow" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59633.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">506</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> A Value-Oriented Metamodel for Small and Medium Enterprises’ Decision Making</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Romain%20Ben%20Taleb">Romain Ben Taleb</a>, <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Montarnal"> Aurélie Montarnal</a>, <a href="https://publications.waset.org/abstracts/search?q=Matthieu%20Lauras"> Matthieu Lauras</a>, <a href="https://publications.waset.org/abstracts/search?q=Mathieu%20Dahan"> Mathieu Dahan</a>, <a href="https://publications.waset.org/abstracts/search?q=Romain%20Miclo"> Romain Miclo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> To be competitive and sustainable, any company has to maximize its value. However, unlike listed companies that can assess their values based on market shares, most Small and Medium Enterprises (SMEs) which are non-listed cannot have direct and live access to this critical information. Traditional accounting reports only give limited insights to SME decision-makers about the real impact of their day-to-day decisions on the company’s performance and value. Most of the time, an SME’s financial valuation is made one time a year as the associated process is time and resource-consuming, requiring several months and external expertise to be completed. To solve this issue, we propose in this paper a value-oriented metamodel that enables real-time and dynamic assessment of the SME’s value based on the large definition of their assets. These assets cover a wider scope of resources of the company and better account for immaterial assets. The proposal, which is illustrated in a case study, discusses the benefits of incorporating assets in the SME valuation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=SME" title="SME">SME</a>, <a href="https://publications.waset.org/abstracts/search?q=metamodel" title=" metamodel"> metamodel</a>, <a href="https://publications.waset.org/abstracts/search?q=decision%20support%20system" title=" decision support system"> decision support system</a>, <a href="https://publications.waset.org/abstracts/search?q=financial%20valuation" title=" financial valuation"> financial valuation</a>, <a href="https://publications.waset.org/abstracts/search?q=assets" title=" assets"> assets</a> </p> <a href="https://publications.waset.org/abstracts/155809/a-value-oriented-metamodel-for-small-and-medium-enterprises-decision-making" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/155809.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">92</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Views on Abortion and Case Law on International and European Levels: Past and Present Jurisprudence</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Cassiers">Aurélie Cassiers</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this presentation, an overview is given of the freedom of states to legislate concerning abortion. Today, access to safe and legal abortion is still a hot topic in many countries in the world. Abortion policies try to strike a balance between women’s rights to self-determination and private life on the one hand, and the protection of the life of unborn children on the other. Each country has different religious, cultural and political views on abortion, and therefore specific legislations. However, citizens may submit a complaint at international courts when they find their national legislation too restrictive. The study is discussed of the development of the ECtHR, UNCHR, and IACHR case law, regarding the question of the ‘right to abort’ and indirectly of the protection of the unborn children. Each relevant case is analyzed to answer the following questions: Is the unborn child protected, and if so, how? Why does the woman want to abort and how is her interest or right protected? How is a fair balance reached between the different interests? Is the state completely free to write policies that restrict abortion? What are the factors to determine the margin of appreciation of the state? In conclusion, does this specific court recognize a right to abort, and if so, under which conditions? To conclude, this presentation shows that each court has its own perspective on and perception of abortion, and its own criteria to determine whether the state is complying with international norms regarding individual liberty and protection of the children. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=abortion" title="abortion">abortion</a>, <a href="https://publications.waset.org/abstracts/search?q=international%20courts" title=" international courts"> international courts</a>, <a href="https://publications.waset.org/abstracts/search?q=unborn%20children" title=" unborn children"> unborn children</a>, <a href="https://publications.waset.org/abstracts/search?q=women%20rights" title=" women rights "> women rights </a> </p> <a href="https://publications.waset.org/abstracts/119975/views-on-abortion-and-case-law-on-international-and-european-levels-past-and-present-jurisprudence" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/119975.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">130</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Chemical Characterization and Prebiotic Effect of Water-Soluble Polysaccharides from Zizyphus lotus Leaves</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zakaria%20Boual">Zakaria Boual</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdellah%20Kemassi"> Abdellah Kemassi</a>, <a href="https://publications.waset.org/abstracts/search?q=Toufik%20Chouana"> Toufik Chouana</a>, <a href="https://publications.waset.org/abstracts/search?q=Philippe%20Michaud"> Philippe Michaud</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Didi%20Ould%20El%20Hadj"> Mohammed Didi Ould El Hadj</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In order to investigate the prebiotic potential of oligosaccharides prepared by chemical hydrolysis of water-soluble polysaccharides (WSP) from Zizyphus lotus leaves, the effect of oligosaccharides on bacterial growth was studied. The chemical composition of WSP was evaluated by colorimetric assays revealed the average values: 7.05±0.73% proteins and 86.21±0.74% carbohydrates, among them 64.81±0.42% are neutral sugar and the rest 16.25±1.62% are uronic acids. The characterization of monosaccharides was determined by high performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) was found to be composed of galactose (23.95%), glucose (21.30%), rhamnose (20.28%), arabinose (9.55%), and glucuronic acid (22.95%). The effects of oligosaccharides on the growth of lactic acid bacteria were compared with those of fructo-oligosaccharide (RP95). The oligosaccharides concentration was 1g/L of man rogosa sharpe broth. Bacterial growth was assessed during 2, 4.5, 6.5, 9, 12, 16 and 24 h by measuring the optical density of the cultures at 600 nm (OD600) and pH values. During fermentation, pH in broth cultures decreased from 6.7 to 5.87±0.15. The enumeration of lactic acid bacteria indicated that oligosaccharides led to a significant increase in bacteria (P≤0.05) compared to the control. The fermentative metabolism appeared to be faster on RP95 than on oligosaccharides from Zizyphus lotus leaves. Both RP95 and oligosaccharides showed clear prebiotic effects, but had differences in fermentation kinetics because of to the different degree of polymerization. This study shows the prebiotic effectiveness of oligosaccharides, and provides proof for the selection of leaves of Zizyphus lotus for use as functional food ingredients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zizyphus%20lotus" title="Zizyphus lotus">Zizyphus lotus</a>, <a href="https://publications.waset.org/abstracts/search?q=polysaccharides" title=" polysaccharides"> polysaccharides</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization" title=" characterization"> characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=prebiotic%20effects" title=" prebiotic effects"> prebiotic effects</a> </p> <a href="https://publications.waset.org/abstracts/41698/chemical-characterization-and-prebiotic-effect-of-water-soluble-polysaccharides-from-zizyphus-lotus-leaves" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41698.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">410</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Metabolic and Phylogenetic Profiling of Rhizobium leguminosarum Strains Isolated from NZ Soils of Varying pH</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anish%20Shah">Anish Shah</a>, <a href="https://publications.waset.org/abstracts/search?q=Steve%20A.%20Wakelin"> Steve A. Wakelin</a>, <a href="https://publications.waset.org/abstracts/search?q=Derrick%20Moot"> Derrick Moot</a>, <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Laugraud"> Aurélie Laugraud</a>, <a href="https://publications.waset.org/abstracts/search?q=Hayley%20J.%20Ridgway"> Hayley J. Ridgway</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A mixed pasture system of ryegrass-clover is used in New Zealand, where clovers are generally inoculated with commercially available strains of rhizobia. The community of rhizobia living in the soil and the way in which they interact with the plant are affected by different biotic and abiotic factors. In general, bacterial richness and diversity in soil varies by soil pH. pH also affects cell physiology and acts as a master variable that controls the wider soil physiochemical conditions such as P availability, Al release and micronutrient availability. As such, pH can have both primary and secondary effects on soil biology and processes. The aim of this work was to investigate the effect of soil pH on the genetic diversity and metabolic profile of Rhizobium leguminosarum strains nodulating clover. Soils were collected from 12 farms across New Zealand which had a pH(water) range of between 4.9 and 7.5, with four acidic (pH 4.9 – 5.5), four ‘neutral’ (5.8 – 6.1) and four alkaline (6.5 – 7.5) soils. Bacteria were recovered from nodules of Trifolium repens (white clover) and T. subterraneum (subterranean clover) grown in the soils. The strains were cultured and screened against a range of pH-amended media to demonstrate whether they were adapted to pH levels similar to their native soils. The strains which showed high relative growth at a given pH (~20% of those isolated) were selected for metabolic and taxonomic profiling. The Omnilog (Biolog Inc., Hayward, CA) phenotype array was used to perform assays on carbon (C) utilisation for selected strains. DNA was extracted from the strains which had differing C utilisation profiles and PCR products for both forward and reverse primers were sequenced for the following genes: 16S rRNA, recA, nodC, nodD and nifH (symbiotic). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bacterial%20diversity" title="bacterial diversity">bacterial diversity</a>, <a href="https://publications.waset.org/abstracts/search?q=clover" title=" clover"> clover</a>, <a href="https://publications.waset.org/abstracts/search?q=metabolic%20and%20taxonomic%20profiling" title=" metabolic and taxonomic profiling"> metabolic and taxonomic profiling</a>, <a href="https://publications.waset.org/abstracts/search?q=pH%20adaptation" title=" pH adaptation"> pH adaptation</a>, <a href="https://publications.waset.org/abstracts/search?q=rhizobia" title=" rhizobia"> rhizobia</a> </p> <a href="https://publications.waset.org/abstracts/70399/metabolic-and-phylogenetic-profiling-of-rhizobium-leguminosarum-strains-isolated-from-nz-soils-of-varying-ph" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70399.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">260</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Deciphering the Action of Neuraminidase in Glioblastoma Models</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nathalie%20Baeza-Kallee">Nathalie Baeza-Kallee</a>, <a href="https://publications.waset.org/abstracts/search?q=Rapha%C3%ABl%20Berg%C3%A8s"> Raphaël Bergès</a>, <a href="https://publications.waset.org/abstracts/search?q=Victoria%20Hein"> Victoria Hein</a>, <a href="https://publications.waset.org/abstracts/search?q=St%C3%A9phanie%20Cabaret"> Stéphanie Cabaret</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Garcia"> Jeremy Garcia</a>, <a href="https://publications.waset.org/abstracts/search?q=Abiga%C3%ABlle%20Gros"> Abigaëlle Gros</a>, <a href="https://publications.waset.org/abstracts/search?q=Emeline%20Tabouret"> Emeline Tabouret</a>, <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Tchoghandjian"> Aurélie Tchoghandjian</a>, <a href="https://publications.waset.org/abstracts/search?q=Carole%20Colin"> Carole Colin</a>, <a href="https://publications.waset.org/abstracts/search?q=Dominique%20Figarella-Branger"> Dominique Figarella-Branger</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Glioblastoma (GBM) contains cancer stem cells that are resistant to treatment. GBM cancer stem cell expresses glycolipids recognized by the A2B5 antibody. A2B5, induced by the enzyme ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyl transferase 3 (ST8Sia3), plays a crucial role in the proliferation, migration, clonogenicity, and tumorigenesis of GBM cancer stem cells. Our aim was to characterize the resulting effects of neuraminidase that remove A2B5 in order to target GBM cancer stem cells. To this end, we set up a GBM organotypic slice model; quantified A2B5 expression by flow cytometry in U87-MG, U87-ST8Sia3, and GBM cancer stem cell lines, treated or not by neuraminidase; performed RNAseq and DNA methylation profiling; and analyzed the ganglioside expression by liquid chromatography-mass spectrometry in these cell lines, treated or not with neuraminidase. Results demonstrated that neuraminidase decreased A2B5 expression, tumor size, and regrowth after surgical removal in the organotypic slice model but did not induce a distinct transcriptomic or epigenetic signature in GBM CSC lines. RNAseq analysis revealed that OLIG2, CHI3L1, TIMP3, TNFAIP2, and TNFAIP6 transcripts were significantly overexpressed in U87-ST8Sia3 compared to U87-MG. RT-qPCR confirmed these results and demonstrated that neuraminidase decreased gene expression in GBM cancer stem cell lines. Moreover, neuraminidase drastically reduced ganglioside expression in GBM cancer stem cell lines. Neuraminidase, by its pleiotropic action, is an attractive local treatment against GBM. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cancer%20stem%20cell" title="cancer stem cell">cancer stem cell</a>, <a href="https://publications.waset.org/abstracts/search?q=ganglioside" title=" ganglioside"> ganglioside</a>, <a href="https://publications.waset.org/abstracts/search?q=glioblastoma" title=" glioblastoma"> glioblastoma</a>, <a href="https://publications.waset.org/abstracts/search?q=targeted%20treatment" title=" targeted treatment"> targeted treatment</a> </p> <a href="https://publications.waset.org/abstracts/171854/deciphering-the-action-of-neuraminidase-in-glioblastoma-models" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171854.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Endocrine Disruptors Effects on the 20-Hydroxyecdysone Concentration and the Vitellogenin Gene Expression in Gammarus sp.</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eric%20Gismondi">Eric Gismondi</a>, <a href="https://publications.waset.org/abstracts/search?q=Aurelie%20Bigot-Clivot"> Aurelie Bigot-Clivot</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Endocrine disruptors (EDCs) are well known to disrupt the development and the reproduction of exposed organisms. Although this point has been studied in vertebrate models, the limited knowledge of the endocrine system of invertebrates makes the evaluation of EDCs effects difficult. However, invertebrates represent the major part of aquatic ecosystems, such as amphipods Gammaridea, which are crucial for their functioning (e.g., litter degradation, food resource). Moreover, gammarids are hosts of parasites such as vertically-transmitted microsporidia (microsporidia VT), which could be confounding factors in assessment of EDC effects. Indeed, some microsporidia VT could have endocrine effects by their own present in the host since it was observed for example, a feminization of juvenile males, which become phenotypic females. This work evaluated the impact of ethinylestradiol (EE₂, estrogenic), cyproterone acetate (CPA, anti-androgenic), 4-hydroxytamoxifen (4HT, anti-estrogenic) and 17α-methyltestosterone (17MT - androgenic), on the 20-hydroxyecdysone concentration (i.e. 20HE - molt process) and the vitellogenin gene expression (i.e. reproduction) in the freshwater amphipod Gammarus pulex, after a 96h laboratory exposure. In addition, the presence of microsporidia VT was verified in order to analyze the effect of this confounding factor. Results of this study shown that, although endocrine systems of invertebrates and vertebrates are different, EDCs proved in vertebrates could also affect biological functions hormonally controlled in invertebrates. Indeed, the molt process of crustaceans was disrupted in the first stage (i.e. 20-HE concentration) and therefore, could affect, at the long term, the population dynamic. In addition, it was observed that G. pulex was differently impacted according to the gender and parasitism, which underline the importance to take into account these confounding factors to better evaluate the EDCs impact on invertebrate populations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=endocrine%20disruption" title="endocrine disruption">endocrine disruption</a>, <a href="https://publications.waset.org/abstracts/search?q=gammarus%20sp." title=" gammarus sp."> gammarus sp.</a>, <a href="https://publications.waset.org/abstracts/search?q=molt" title=" molt"> molt</a>, <a href="https://publications.waset.org/abstracts/search?q=parasitism" title=" parasitism"> parasitism</a> </p> <a href="https://publications.waset.org/abstracts/79158/endocrine-disruptors-effects-on-the-20-hydroxyecdysone-concentration-and-the-vitellogenin-gene-expression-in-gammarus-sp" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79158.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">165</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Using Biofunctool® Index to Assess Soil Quality after Eight Years of Conservation Agriculture in New Caledonia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Remy%20Kulagowski">Remy Kulagowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Tobias%20Sturm"> Tobias Sturm</a>, <a href="https://publications.waset.org/abstracts/search?q=Audrey%20Leopold"> Audrey Leopold</a>, <a href="https://publications.waset.org/abstracts/search?q=Aurelie%20Metay"> Aurelie Metay</a>, <a href="https://publications.waset.org/abstracts/search?q=Josephine%20Peigne"> Josephine Peigne</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexis%20Thoumazeau"> Alexis Thoumazeau</a>, <a href="https://publications.waset.org/abstracts/search?q=Alain%20Brauman"> Alain Brauman</a>, <a href="https://publications.waset.org/abstracts/search?q=Bruno%20Fogliani"> Bruno Fogliani</a>, <a href="https://publications.waset.org/abstracts/search?q=Florent%20Tivet"> Florent Tivet</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A major challenge for agriculture is to enhance productivity while limiting the impact on the environment. Conservation agriculture (CA) is one strategy whereby both sustainability and productivity can be achieved by preserving and improving the soil quality. Soils provide and regulate a large number of ecosystem services (ES) such as agricultural productivity and climate change adaptation and mitigation. The aim of this study is to assess the impacts of contrasted CA crop management on soil functions for maize (Zea mays L.) cultivation in an eight years field experiment (2010-2018). The study included two CA practices: direct seeding in dead mulch (DM) and living mulch (LM), and conventional plough-based tillage (CT) practices on a fluvisol in New Caledonia (French Archipelago in the South Pacific). In 2018, soil quality of the cropping systems were evaluated with the Biofunctool® set of indicators, that consists in twelve integrative, in-field, and low-tech indicators assessing the biological, physical and chemical properties of soils. Main soil functions were evaluated including (i) carbon transformation, (ii) structure maintenance, and (iii) nutrient cycling in the ten first soil centimeters. The results showed significant higher score for soil structure maintenance (e.g., aggregate stability, water infiltration) and carbon transformation function (e.g., soil respiration, labile carbon) under CA in DM and LM when compared with CT. Score of carbon transformation index was higher in DM compared with LM. However, no significant effect of cropping systems was observed on nutrient cycling (i.e., nitrogen and phosphorus). In conclusion, the aggregated synthetic scores of soil multi-functions evaluated with Biofunctool® demonstrate that CA cropping systems lead to a better soil functioning. Further analysis of the results with agronomic performance of the soil-crop systems would allow to better understand the links between soil functioning and production ES of CA. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=conservation%20agriculture" title="conservation agriculture">conservation agriculture</a>, <a href="https://publications.waset.org/abstracts/search?q=cropping%20systems" title=" cropping systems"> cropping systems</a>, <a href="https://publications.waset.org/abstracts/search?q=ecosystem%20services" title=" ecosystem services"> ecosystem services</a>, <a href="https://publications.waset.org/abstracts/search?q=soil%20functions" title=" soil functions"> soil functions</a> </p> <a href="https://publications.waset.org/abstracts/106119/using-biofunctool-index-to-assess-soil-quality-after-eight-years-of-conservation-agriculture-in-new-caledonia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/106119.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">157</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Additive Friction Stir Manufacturing Process: Interest in Understanding Thermal Phenomena and Numerical Modeling of the Temperature Rise Phase</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Antoine%20Lauvray">Antoine Lauvray</a>, <a href="https://publications.waset.org/abstracts/search?q=Fabien%20Poulhaon"> Fabien Poulhaon</a>, <a href="https://publications.waset.org/abstracts/search?q=Pierre%20Michaud"> Pierre Michaud</a>, <a href="https://publications.waset.org/abstracts/search?q=Pierre%20Joyot"> Pierre Joyot</a>, <a href="https://publications.waset.org/abstracts/search?q=Emmanuel%20Duc"> Emmanuel Duc</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Additive Friction Stir Manufacturing (AFSM) is a new industrial process that follows the emergence of friction-based processes. The AFSM process is a solid-state additive process using the energy produced by the friction at the interface between a rotating non-consumable tool and a substrate. Friction depends on various parameters like axial force, rotation speed or friction coefficient. The feeder material is a metallic rod that flows through a hole in the tool. Unlike in Friction Stir Welding (FSW) where abundant literature exists and addresses many aspects going from process implementation to characterization and modeling, there are still few research works focusing on AFSM. Therefore, there is still a lack of understanding of the physical phenomena taking place during the process. This research work aims at a better AFSM process understanding and implementation, thanks to numerical simulation and experimental validation performed on a prototype effector. Such an approach is considered a promising way for studying the influence of the process parameters and to finally identify a process window that seems relevant. The deposition of material through the AFSM process takes place in several phases. In chronological order these phases are the docking phase, the dwell time phase, the deposition phase, and the removal phase. The present work focuses on the dwell time phase that enables the temperature rise of the system composed of the tool, the filler material, and the substrate and due to pure friction. Analytic modeling of heat generation based on friction considers as main parameters the rotational speed and the contact pressure. Another parameter considered influential is the friction coefficient assumed to be variable due to the self-lubrication of the system with the rise in temperature or the materials in contact roughness smoothing over time. This study proposes, through numerical modeling followed by experimental validation, to question the influence of the various input parameters on the dwell time phase. Rotation speed, temperature, spindle torque, and axial force are the main monitored parameters during experimentations and serve as reference data for the calibration of the numerical model. This research shows that the geometry of the tool as well as fluctuations of the input parameters like axial force and rotational speed are very influential on the temperature reached and/or the time required to reach the targeted temperature. The main outcome is the prediction of a process window which is a key result for a more efficient process implementation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=numerical%20model" title="numerical model">numerical model</a>, <a href="https://publications.waset.org/abstracts/search?q=additive%20manufacturing" title=" additive manufacturing"> additive manufacturing</a>, <a href="https://publications.waset.org/abstracts/search?q=friction" title=" friction"> friction</a>, <a href="https://publications.waset.org/abstracts/search?q=process" title=" process"> process</a> </p> <a href="https://publications.waset.org/abstracts/133073/additive-friction-stir-manufacturing-process-interest-in-understanding-thermal-phenomena-and-numerical-modeling-of-the-temperature-rise-phase" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133073.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">147</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Electrical Decomposition of Time Series of Power Consumption</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noura%20Al%20Akkari">Noura Al Akkari</a>, <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Foucquier"> Aurélie Foucquier</a>, <a href="https://publications.waset.org/abstracts/search?q=Sylvain%20Lespinats"> Sylvain Lespinats</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Load monitoring is a management process for energy consumption towards energy savings and energy efficiency. Non Intrusive Load Monitoring (NILM) is one method of load monitoring used for disaggregation purposes. NILM is a technique for identifying individual appliances based on the analysis of the whole residence data retrieved from the main power meter of the house. Our NILM framework starts with data acquisition, followed by data preprocessing, then event detection, feature extraction, then general appliance modeling and identification at the final stage. The event detection stage is a core component of NILM process since event detection techniques lead to the extraction of appliance features. Appliance features are required for the accurate identification of the household devices. In this research work, we aim at developing a new event detection methodology with accurate load disaggregation to extract appliance features. Time-domain features extracted are used for tuning general appliance models for appliance identification and classification steps. We use unsupervised algorithms such as Dynamic Time Warping (DTW). The proposed method relies on detecting areas of operation of each residential appliance based on the power demand. Then, detecting the time at which each selected appliance changes its states. In order to fit with practical existing smart meters capabilities, we work on low sampling data with a frequency of (1/60) Hz. The data is simulated on Load Profile Generator software (LPG), which was not previously taken into consideration for NILM purposes in the literature. LPG is a numerical software that uses behaviour simulation of people inside the house to generate residential energy consumption data. The proposed event detection method targets low consumption loads that are difficult to detect. Also, it facilitates the extraction of specific features used for general appliance modeling. In addition to this, the identification process includes unsupervised techniques such as DTW. To our best knowledge, there exist few unsupervised techniques employed with low sampling data in comparison to the many supervised techniques used for such cases. We extract a power interval at which falls the operation of the selected appliance along with a time vector for the values delimiting the state transitions of the appliance. After this, appliance signatures are formed from extracted power, geometrical and statistical features. Afterwards, those formed signatures are used to tune general model types for appliances identification using unsupervised algorithms. This method is evaluated using both simulated data on LPG and real-time Reference Energy Disaggregation Dataset (REDD). For that, we compute performance metrics using confusion matrix based metrics, considering accuracy, precision, recall and error-rate. The performance analysis of our methodology is then compared with other detection techniques previously used in the literature review, such as detection techniques based on statistical variations and abrupt changes (Variance Sliding Window and Cumulative Sum). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electrical%20disaggregation" title="electrical disaggregation">electrical disaggregation</a>, <a href="https://publications.waset.org/abstracts/search?q=DTW" title=" DTW"> DTW</a>, <a href="https://publications.waset.org/abstracts/search?q=general%20appliance%20modeling" title=" general appliance modeling"> general appliance modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=event%20detection" title=" event detection"> event detection</a> </p> <a href="https://publications.waset.org/abstracts/170691/electrical-decomposition-of-time-series-of-power-consumption" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/170691.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">78</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Empirical Decomposition of Time Series of Power Consumption</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noura%20Al%20Akkari">Noura Al Akkari</a>, <a href="https://publications.waset.org/abstracts/search?q=Aur%C3%A9lie%20Foucquier"> Aurélie Foucquier</a>, <a href="https://publications.waset.org/abstracts/search?q=Sylvain%20Lespinats"> Sylvain Lespinats</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Load monitoring is a management process for energy consumption towards energy savings and energy efficiency. Non Intrusive Load Monitoring (NILM) is one method of load monitoring used for disaggregation purposes. NILM is a technique for identifying individual appliances based on the analysis of the whole residence data retrieved from the main power meter of the house. Our NILM framework starts with data acquisition, followed by data preprocessing, then event detection, feature extraction, then general appliance modeling and identification at the final stage. The event detection stage is a core component of NILM process since event detection techniques lead to the extraction of appliance features. Appliance features are required for the accurate identification of the household devices. In this research work, we aim at developing a new event detection methodology with accurate load disaggregation to extract appliance features. Time-domain features extracted are used for tuning general appliance models for appliance identification and classification steps. We use unsupervised algorithms such as Dynamic Time Warping (DTW). The proposed method relies on detecting areas of operation of each residential appliance based on the power demand. Then, detecting the time at which each selected appliance changes its states. In order to fit with practical existing smart meters capabilities, we work on low sampling data with a frequency of (1/60) Hz. The data is simulated on Load Profile Generator software (LPG), which was not previously taken into consideration for NILM purposes in the literature. LPG is a numerical software that uses behaviour simulation of people inside the house to generate residential energy consumption data. The proposed event detection method targets low consumption loads that are difficult to detect. Also, it facilitates the extraction of specific features used for general appliance modeling. In addition to this, the identification process includes unsupervised techniques such as DTW. To our best knowledge, there exist few unsupervised techniques employed with low sampling data in comparison to the many supervised techniques used for such cases. We extract a power interval at which falls the operation of the selected appliance along with a time vector for the values delimiting the state transitions of the appliance. After this, appliance signatures are formed from extracted power, geometrical and statistical features. Afterwards, those formed signatures are used to tune general model types for appliances identification using unsupervised algorithms. This method is evaluated using both simulated data on LPG and real-time Reference Energy Disaggregation Dataset (REDD). For that, we compute performance metrics using confusion matrix based metrics, considering accuracy, precision, recall and error-rate. The performance analysis of our methodology is then compared with other detection techniques previously used in the literature review, such as detection techniques based on statistical variations and abrupt changes (Variance Sliding Window and Cumulative Sum). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=general%20appliance%20model" title="general appliance model">general appliance model</a>, <a href="https://publications.waset.org/abstracts/search?q=non%20intrusive%20load%20monitoring" title=" non intrusive load monitoring"> non intrusive load monitoring</a>, <a href="https://publications.waset.org/abstracts/search?q=events%20detection" title=" events detection"> events detection</a>, <a href="https://publications.waset.org/abstracts/search?q=unsupervised%20techniques%3B" title=" unsupervised techniques;"> unsupervised techniques;</a> </p> <a 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