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data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Un article de Wikipédia, l'encyclopédie libre.</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="fr" dir="ltr"><p>La <b>lymphangiomatose</b> est une maladie rare caractérisée par une prolifération diffuse des vaisseaux lymphatiques. </p><p>Un lymphangiome est une masse anarchique de vaisseaux lymphatiques. Dans la lymphangiomatose, les lymphangiomes (ou <a href="/wiki/Kyste_(m%C3%A9decine)" title="Kyste (médecine)">kystes</a>) sont multiples, et répartis d'une manière généralisée ou multifocale<sup id="cite_ref-hwang2009_1-0" class="reference"><a href="#cite_note-hwang2009-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> (c'est-à-dire impliquant plusieurs parties du corps). La lymphangiomatose résulte d'un développement anormal du système lymphatique mais ses causes ne sont pas bien connues<sup id="cite_ref-marom2004_2-0" class="reference"><a href="#cite_note-marom2004-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>. </p><p>La maladie peut affecter les organes internes, les os, les tissus mous et / ou la peau<sup id="cite_ref-leboit_3-0" class="reference"><a href="#cite_note-leboit-3"><span class="cite_crochet">[</span>3<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-yang2006_4-0" class="reference"><a href="#cite_note-yang2006-4"><span class="cite_crochet">[</span>4<span class="cite_crochet">]</span></a></sup>. Elle est plus fréquente chez les enfants et les jeunes adultes<sup id="cite_ref-weiss_5-0" class="reference"><a href="#cite_note-weiss-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup>. Les symptômes et le pronostic varient considérablement entre les individus et selon les organes concernés. Le terme lymphangiomatose provient des mots «<a href="/wiki/Lymphe" title="Lymphe">lymphe</a>» (liquide biologique transporté par le système lymphatique), «angio» (concernant les vaisseaux), «oma» (tumeur ou kyste), «tose »(maladie)<sup id="cite_ref-lgdalliance_6-0" class="reference"><a href="#cite_note-lgdalliance-6"><span class="cite_crochet">[</span>6<span class="cite_crochet">]</span></a></sup>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Signes_et_symptômes"><span id="Signes_et_sympt.C3.B4mes"></span>Signes et symptômes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lymphangiomatose&veaction=edit&section=1" title="Modifier la section : Signes et symptômes" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Lymphangiomatose&action=edit&section=1" title="Modifier le code source de la section : Signes et symptômes"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Presque toutes les parties du corps peuvent être affectées, à l'exception du <a href="/wiki/Syst%C3%A8me_nerveux_central" title="Système nerveux central">système nerveux central</a> en raison de son manque de vaisseaux lymphatiques<sup id="cite_ref-timke2007_7-0" class="reference"><a href="#cite_note-timke2007-7"><span class="cite_crochet">[</span>7<span class="cite_crochet">]</span></a></sup>. Les signes et symptômes varient selon les zones du corps touchées<sup id="cite_ref-weiss_5-1" class="reference"><a href="#cite_note-weiss-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup>. </p><p>Les patients peuvent présenter les complications suivantes : <a href="/wiki/%C3%89panchement_p%C3%A9ricardique" title="Épanchement péricardique">épanchement péricardique</a> (liquide autour du cœur), épanchement pleural (accumulation de liquide autour de la cavité pulmonaire), ascite (accumulation de liquide dans la cavité abdominale), fractures osseuses, lésions cutanées<sup id="cite_ref-leboit_3-1" class="reference"><a href="#cite_note-leboit-3"><span class="cite_crochet">[</span>3<span class="cite_crochet">]</span></a></sup>, fièvre et hémorragie interne<sup id="cite_ref-aviv_8-0" class="reference"><a href="#cite_note-aviv-8"><span class="cite_crochet">[</span>8<span class="cite_crochet">]</span></a></sup>. Le fluide impliqué dans les épanchements est le chyle (liquide d'apparence laiteuse), fait de lymphe et de graisse provenant du système digestif. Les symptômes comprennent l'essoufflement, la toux<sup id="cite_ref-cagle_9-0" class="reference"><a href="#cite_note-cagle-9"><span class="cite_crochet">[</span>9<span class="cite_crochet">]</span></a></sup>, la respiration difficile (<a href="/wiki/Inhalation" title="Inhalation">inhalation</a>), la douleur sévère dans la cavité abdominale et la cavité pelvienne, et lymphœdème (gonflement). Certains patients ne présentent aucun symptôme, mais montrent des résultats anormaux d'imagerie médicale<sup id="cite_ref-yang2006_4-1" class="reference"><a href="#cite_note-yang2006-4"><span class="cite_crochet">[</span>4<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Diagnostic">Diagnostic</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lymphangiomatose&veaction=edit&section=2" title="Modifier la section : Diagnostic" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Lymphangiomatose&action=edit&section=2" title="Modifier le code source de la section : Diagnostic"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Il n'existe aucune norme actuelle pour le diagnostic de cette maladie. Les symptômes, la présentation clinique et les constatations radiographiques typiques peuvent aider au diagnostic<sup id="cite_ref-agarwal2008_10-0" class="reference"><a href="#cite_note-agarwal2008-10"><span class="cite_crochet">[</span>10<span class="cite_crochet">]</span></a></sup>. Une biopsie est la méthode ultime pour le diagnostic, mais elle n'est pas toujours possible. </p><p>L'imagerie par résonance magnétique du corps entier permet une bonne évaluation de l'étendue de la maladie<sup id="cite_ref-yang2006_4-2" class="reference"><a href="#cite_note-yang2006-4"><span class="cite_crochet">[</span>4<span class="cite_crochet">]</span></a></sup>. L'IRM donne de meilleurs résultats que la tomodensitométrie<sup id="cite_ref-konez2000_11-0" class="reference"><a href="#cite_note-konez2000-11"><span class="cite_crochet">[</span>11<span class="cite_crochet">]</span></a></sup>, bien que le CT scan soit aussi fréquemment utilisé. </p><p>La lymphangiomatose peut être confondue avec d'autres maladies, y compris la dysplasie lymphatique, lymphangiectasie, et la <a href="/wiki/Lymphangiol%C3%A9iomyomatose" title="Lymphangioléiomyomatose">lymphangioléiomyomatose</a> (LAM)<sup id="cite_ref-john2000_12-0" class="reference"><a href="#cite_note-john2000-12"><span class="cite_crochet">[</span>12<span class="cite_crochet">]</span></a></sup>. La LAM est principalement trouvée chez les femmes en âge de procréer<sup id="cite_ref-ispub_13-0" class="reference"><a href="#cite_note-ispub-13"><span class="cite_crochet">[</span>13<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Traitement">Traitement</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lymphangiomatose&veaction=edit&section=3" title="Modifier la section : Traitement" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Lymphangiomatose&action=edit&section=3" title="Modifier le code source de la section : Traitement"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Dans les cas où il est possible d'enlever les tissus lymphatiques anormaux par la chirurgie, les patients peuvent être guéris. Cependant, dans la lymphangiomatose, la plupart des patients sont inopérables en raison du caractère infiltrant des vaisseaux lymphatiques<sup id="cite_ref-timke2007_7-1" class="reference"><a href="#cite_note-timke2007-7"><span class="cite_crochet">[</span>7<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-rostom2000_14-0" class="reference"><a href="#cite_note-rostom2000-14"><span class="cite_crochet">[</span>14<span class="cite_crochet">]</span></a></sup>. Les traitements sont ainsi en général palliatifs (pour soulager les symptômes) ou pour ralentir la progression de la maladie. </p><p>Les facteurs de croissance endothéliaux vasculaires sont connus pour réguler la croissance des vaisseaux lymphatiques. Une protéine appelée VEGFR3 est particulièrement importante dans le système lymphatique<sup id="cite_ref-timke2007_7-2" class="reference"><a href="#cite_note-timke2007-7"><span class="cite_crochet">[</span>7<span class="cite_crochet">]</span></a></sup>. Cela signifie que le traitement par inhibiteurs de croissance vasculaire peut ralentir la progression de la maladie. </p><p>Une grande variété d'autres traitements ont été essayés. Il s'agit notamment<sup id="cite_ref-aviv_8-1" class="reference"><a href="#cite_note-aviv-8"><span class="cite_crochet">[</span>8<span class="cite_crochet">]</span></a></sup> : </p> <ul><li>drainage des espaces autour des poumons et autour du cœur pour éliminer le liquide provenant de ces zones (<a href="/wiki/Drainage_pleural" title="Drainage pleural">drainage pleural</a> et péricardique) ;</li> <li><a href="/wiki/Pleurod%C3%A8se" title="Pleurodèse">pleurodèse</a> (une procédure pour restreindre l'espace autour du poumon où le fluide peut s'accumuler) ;</li> <li>un régime sans graisse à l'exception de graisses de triglycérides à chaîne moyenne (un certain type de matière grasse) ;</li> <li>traitements médicamenteux, y compris methylprednisolone, bisphosphonates, l'interféron alpha, chlorambucil / étoposide ;</li> <li>radiothérapie ;</li> <li>amputation ;</li> <li>transplantation pulmonaire<sup id="cite_ref-wileyPOINTcom_15-0" class="reference"><a href="#cite_note-wileyPOINTcom-15"><span class="cite_crochet">[</span>15<span class="cite_crochet">]</span></a></sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="Pronostic">Pronostic</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lymphangiomatose&veaction=edit&section=4" title="Modifier la section : Pronostic" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Lymphangiomatose&action=edit&section=4" title="Modifier le code source de la section : Pronostic"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Les tumeurs créées par la prolifération de vaisseaux lymphatiques ne sont pas métastatiques (cancéreuse)<sup id="cite_ref-chew_16-0" class="reference"><a href="#cite_note-chew-16"><span class="cite_crochet">[</span>16<span class="cite_crochet">]</span></a></sup>, mais peuvent néanmoins montrer une croissance agressive. </p><p>Le pronostic dépend de l'étendue de la maladie<sup id="cite_ref-weiss_5-2" class="reference"><a href="#cite_note-weiss-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup>. Quand il y a beaucoup de tissus mous impliqués, ainsi qu'un <a href="/wiki/Chylothorax" title="Chylothorax">chylothorax</a> (lymphe autour de la cavité pulmonaire) le pronostic est généralement mauvais. Si seules les extrémités sont touchées, le pronostic est meilleur<sup id="cite_ref-chew_16-1" class="reference"><a href="#cite_note-chew-16"><span class="cite_crochet">[</span>16<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Histoire">Histoire</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lymphangiomatose&veaction=edit&section=5" title="Modifier la section : Histoire" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Lymphangiomatose&action=edit&section=5" title="Modifier le code source de la section : Histoire"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>La lymphangiomatose généralisée a été décrite pour la première en 1828<sup id="cite_ref-wong2008_17-0" class="reference"><a href="#cite_note-wong2008-17"><span class="cite_crochet">[</span>17<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading2"><h2 id="Notes_et_références"><span id="Notes_et_r.C3.A9f.C3.A9rences"></span>Notes et références</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lymphangiomatose&veaction=edit&section=6" title="Modifier la section : Notes et références" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Lymphangiomatose&action=edit&section=6" title="Modifier le code source de la section : Notes et références"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="references-small decimal" style=""><div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-hwang2009-1"><span class="mw-cite-backlink noprint"><a href="#cite_ref-hwang2009_1-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Hwang, SS; Choi; Park (2009) « Cavernous mesenteric lymphangiomatosis mimicking metastasis in a patient with rectal cancer: a case report » <i>World journal of gastroenterology : WJG</i> 15(31): 3947–9. <small class="plainlinks noarchive"><a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <a rel="nofollow" class="external text" href="https://dx.doi.org/10.3748%2Fwjg.15.3947">10.3748/wjg.15.3947</a></small> <span class="reflink plainlinksneverexpand"><a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/19701979">19701979</a></span></span> </li> <li id="cite_note-marom2004-2"><span class="mw-cite-backlink noprint"><a href="#cite_ref-marom2004_2-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Marom, EM; Moran, CA; Munden, RF (2004) « Generalized lymphangiomatosis » <i>AJR. American journal of roentgenology</i> 182(4):1068. <span class="reflink plainlinksneverexpand"><a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/15039189">15039189</a></span></span> </li> <li id="cite_note-leboit-3"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-leboit_3-0">a</a> et <a href="#cite_ref-leboit_3-1">b</a></sup> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <i>Pathology and genetics of skin tumours</i>, Volume 6 By Philip E. LeBoit, <abbr class="abbr" title="page">p.</abbr> 249</span> </li> <li id="cite_note-yang2006-4"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-yang2006_4-0">a</a> <a href="#cite_ref-yang2006_4-1">b</a> et <a href="#cite_ref-yang2006_4-2">c</a></sup> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Dong Hyun Yang, Hyun Woo Goo, Korean J Radiol 2006;7:287-291</span> </li> <li id="cite_note-weiss-5"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-weiss_5-0">a</a> <a href="#cite_ref-weiss_5-1">b</a> et <a href="#cite_ref-weiss_5-2">c</a></sup> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <i>Enzinger and Weiss's soft tissue tumors</i>, By Sharon W. Weiss, John R. Goldblum, Franz M. Enzinger, <abbr class="abbr" title="page">p.</abbr> 967</span> </li> <li id="cite_note-lgdalliance-6"><span class="mw-cite-backlink noprint"><a href="#cite_ref-lgdalliance_6-0">↑</a> </span><span class="reference-text"> <a rel="nofollow" class="external free" href="http://www.lgdalliance.org/en/aboutLymphangiomatosis/Default.aspx">http://www.lgdalliance.org/en/aboutLymphangiomatosis/Default.aspx</a></span> </li> <li id="cite_note-timke2007-7"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-timke2007_7-0">a</a> <a href="#cite_ref-timke2007_7-1">b</a> et <a href="#cite_ref-timke2007_7-2">c</a></sup> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Christian Timke, Martin F. Krause, Hans-Conrad Oppermann, Ivo Leuschner et Alexander Claviez. « Interferon Alpha 2b Treatment in an Eleven-Year-Old Boy With Disseminated Lymphangiomatosis » <i>Pediatr Blood Cancer</i> 2007;48:108–111.</span> </li> <li id="cite_note-aviv-8"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-aviv_8-0">a</a> et <a href="#cite_ref-aviv_8-1">b</a></sup> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> R. I. Aviv, K. McHugh, J. Hunt. <i>Angiomatosis of Bone and Soft Tissue: A Spectrum of Disease from Diffuse Lymphangiomatosis to Vanishing Bone Disease in Young Patients</i></span> </li> <li id="cite_note-cagle-9"><span class="mw-cite-backlink noprint"><a href="#cite_ref-cagle_9-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Philip T. Cagle, Timothy C. Allen, Roberto Barrios, Carlos Bedrossian, Megan K Dishop. <i>Color Atlas and Text of Pulmonary Pathology</i>.</span> </li> <li id="cite_note-agarwal2008-10"><span class="mw-cite-backlink noprint"><a href="#cite_ref-agarwal2008_10-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Agarwal P, Matzinger F, Seely J. (2008) « Case 132: Lymphangiomatosis » <i>Radiology</i> 247(1):288–290. <small class="plainlinks noarchive"><a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1148%2Fradiol.2471042092">10.1148/radiol.2471042092</a></small> <span class="reflink plainlinksneverexpand"><a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/18372473">18372473</a></span></span> </li> <li id="cite_note-konez2000-11"><span class="mw-cite-backlink noprint"><a href="#cite_ref-konez2000_11-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Orhan Konez, Pranav K.Vyas, Manish Goyal. « Disseminated lymphangiomatosis presenting with massive chylothorax » <i>Pediatr Radiol</i>. (2000) 30: 35±37</span> </li> <li id="cite_note-john2000-12"><span class="mw-cite-backlink noprint"><a href="#cite_ref-john2000_12-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> John LF, Gerald JB, Thomas VC. <i><abbr class="abbr" title="et alii (« et d’autres »)" lang="la">et al.</abbr></i> « Thoracic Lymphangiomas, Lymphangiectasis, Lymphangiomatosis, and Lymphatic Dysplasia Syndrome » <i>Am J Respir Crit Care Med</i>. 2000; 161: 1037-1046.</span> </li> <li id="cite_note-ispub-13"><span class="mw-cite-backlink noprint"><a href="#cite_ref-ispub_13-0">↑</a> </span><span class="reference-text"> <a rel="nofollow" class="external free" href="http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijpm/vol5n2/malignant.xml">http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijpm/vol5n2/malignant.xml</a></span> </li> <li id="cite_note-rostom2000-14"><span class="mw-cite-backlink noprint"><a href="#cite_ref-rostom2000_14-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Rostom AY. « Treatment of thoracic lymphangiomatosis » <i>Arch Dis Child</i> 2000;83:138-139</span> </li> <li id="cite_note-wileyPOINTcom-15"><span class="mw-cite-backlink noprint"><a href="#cite_ref-wileyPOINTcom_15-0">↑</a> </span><span class="reference-text"> <a rel="nofollow" class="external free" href="http://www3.interscience.wiley.com/journal/121356527/abstract?CRETRY=1&SRETRY=0">http://www3.interscience.wiley.com/journal/121356527/abstract?CRETRY=1&SRETRY=0</a></span> </li> <li id="cite_note-chew-16"><span class="mw-cite-backlink noprint">↑ <sup><a href="#cite_ref-chew_16-0">a</a> et <a href="#cite_ref-chew_16-1">b</a></sup> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Felix S. Chew, Catherine C. Roberts, Anand P. Lalaji. « Musculoskeletal imaging: a teaching file »</span> </li> <li id="cite_note-wong2008-17"><span class="mw-cite-backlink noprint"><a href="#cite_ref-wong2008_17-0">↑</a> </span><span class="reference-text"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Wong CS, Chu TY. (2008) « Clinical and radiological features of generalised lymphangiomatosis » <i>Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine</i> 14(5):402–4. <span class="reflink plainlinksneverexpand"><a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/18840914">18840914</a></span></span> </li> </ol></div> </div> <div class="mw-heading mw-heading2"><h2 id="Liens_externes">Liens externes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Lymphangiomatose&veaction=edit&section=7" title="Modifier la section : Liens externes" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Lymphangiomatose&action=edit&section=7" title="Modifier le code source de la section : Liens externes"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> <a rel="nofollow" class="external text" href="http://www.lgdalliance.org/">alliance pour la lymphangiomatose et la maladie de Gorham</a></li> <li><a rel="nofollow" class="external text" href="https://www.lgda.eu/">alliance pour la lymphangiomatose et la maladie de Gorham (Europe)</a></li> <li>Revue médicale suisse Lymphangiomatose pulmonaire diffuse : description de cas et revue de la littérature (en français)</li></ul> <p><a rel="nofollow" class="external free" href="http://rms.medhyg.ch/article.php?VOLUME=342&PP=1125">http://rms.medhyg.ch/article.php?VOLUME=342&PP=1125</a> </p> <ul><li>L'Asociacion de Lucha contra la Enfermedad de Gorham (site en français) <a rel="nofollow" class="external free" href="http://gorhams.org/asociacion_fr.html">http://gorhams.org/asociacion_fr.html</a></li></ul> <ul id="bandeau-portail" class="bandeau-portail"><li><span class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a href="/wiki/Portail:M%C3%A9decine" title="Portail de la médecine"><img alt="icône décorative" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Star_of_life2.svg/24px-Star_of_life2.svg.png" decoding="async" width="24" height="24" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Star_of_life2.svg/36px-Star_of_life2.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Star_of_life2.svg/48px-Star_of_life2.svg.png 2x" data-file-width="192" data-file-height="192" /></a></span></span> <span class="bandeau-portail-texte"><a href="/wiki/Portail:M%C3%A9decine" title="Portail:Médecine">Portail de la médecine</a></span> </span></li> </ul>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&useformat=desktop" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Ce document provient de « <a dir="ltr" href="https://fr.wikipedia.org/w/index.php?title=Lymphangiomatose&oldid=204439664">https://fr.wikipedia.org/w/index.php?title=Lymphangiomatose&oldid=204439664</a> ».</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Cat%C3%A9gorie:Accueil" title="Catégorie:Accueil">Catégorie</a> : <ul><li><a href="/wiki/Cat%C3%A9gorie:Maladie_rare" title="Catégorie:Maladie rare">Maladie rare</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Catégories cachées : <ul><li><a href="/wiki/Cat%C3%A9gorie:Portail:M%C3%A9decine/Articles_li%C3%A9s" title="Catégorie:Portail:Médecine/Articles liés">Portail:Médecine/Articles liés</a></li><li><a href="/wiki/Cat%C3%A9gorie:Portail:Biologie/Articles_li%C3%A9s" title="Catégorie:Portail:Biologie/Articles liés">Portail:Biologie/Articles liés</a></li><li><a href="/wiki/Cat%C3%A9gorie:Portail:Sciences/Articles_li%C3%A9s" title="Catégorie:Portail:Sciences/Articles liés">Portail:Sciences/Articles liés</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> La dernière modification de cette page a été faite le 20 mai 2023 à 18:11.</li> <li id="footer-info-copyright"><span style="white-space: normal"><a href="/wiki/Wikip%C3%A9dia:Citation_et_r%C3%A9utilisation_du_contenu_de_Wikip%C3%A9dia" title="Wikipédia:Citation et réutilisation du contenu de Wikipédia">Droit d'auteur</a> : les textes sont disponibles sous <a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.fr">licence Creative Commons attribution, partage dans les mêmes conditions</a> ; d’autres conditions peuvent s’appliquer. 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