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COPD Statistics & Facts in the US (2023)

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COPD causes the death of over 150,000 Americans yearly, or one person every 4 minutes." /> <link rel="canonical" href="https://cfah.org/copd-statistics/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="COPD Statistics &amp; Facts (2024): How Common Is COPD?" /> <meta property="og:description" content="Nearly 16 million Americans are diagnosed with chronic obstructive pulmonary disease (COPD). COPD causes the death of over 150,000 Americans yearly, or one person every 4 minutes." /> <meta property="og:url" content="https://cfah.org/copd-statistics/" /> <meta property="og:site_name" content="CFAH" /> <meta property="article:published_time" content="2022-12-30T14:52:27+00:00" /> <meta property="article:modified_time" content="2024-01-11T22:36:28+00:00" /> <meta property="og:image" content="https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-scaled.jpg?_t=1705012590" /> <meta property="og:image:width" content="2560" /> <meta property="og:image:height" content="1440" /> <meta property="og:image:type" content="image/jpeg" /> <meta name="author" content="Nina Julia" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:label1" content="Written by" /> <meta name="twitter:data1" content="Nina Julia" /> <meta name="twitter:label2" content="Est. reading time" /> <meta name="twitter:data2" content="32 minutes" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebPage","@id":"https://cfah.org/copd-statistics/","url":"https://cfah.org/copd-statistics/","name":"COPD Statistics & Facts in the US (2023)","isPartOf":{"@id":"https://cfah.org/#website"},"primaryImageOfPage":{"@id":"https://cfah.org/copd-statistics/#primaryimage"},"image":{"@id":"https://cfah.org/copd-statistics/#primaryimage"},"thumbnailUrl":"https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-scaled.jpg","datePublished":"2022-12-30T14:52:27+00:00","dateModified":"2024-01-11T22:36:28+00:00","author":{"@id":"https://cfah.org/#/schema/person/2dec1ce9199e5234cad645b5f8f89885"},"description":"Nearly 16 million Americans are diagnosed with chronic obstructive pulmonary disease (COPD). 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height="1080" src="https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-1920x1080.jpg" class="attachment-cfah_post_thumbnail_full size-cfah_post_thumbnail_full wp-post-image" alt="Illustration of lungs with COPD" decoding="async" srcset="https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-1920x1080.jpg 1920w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-300x169.jpg 300w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-1024x576.jpg 1024w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-768x432.jpg 768w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-1536x864.jpg 1536w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-2048x1152.jpg 2048w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-720x405.jpg 720w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-105x59.jpg 105w, https://cfah.org/wp-content/uploads/2022/12/Featured-Image-COPD-70x39.jpg 70w" sizes="(max-width: 1920px) 100vw, 1920px" /> </div> <div class="single--header-meta row between-xs middle-xs"> <div class="meta--info"> <span class='author'>Written by Nina Julia</span> | <span class='date'>Last updated: January 11, 2024</span> </div> <div class="meta--comments"> </div> </div> <div class="single--sidebar-m"> <div class="sidebar--widget"><div class="sidebar--title"><h5>Table of Contents</h5></div><ul class="toc_widget_list no_bullets"><li><a href="#Report_Highlights">Report Highlights:</a></li><li><a href="#COPD_Prevalence_Mortality_Demographics_and_Statistics">COPD Prevalence &amp; Mortality Demographics and Statistics</a><ul><li><a href="#How_Many_Deaths_Does_COPD_Cause">How Many Deaths Does COPD Cause?</a></li><li><a href="#COPD_Mortality_Statistics_In_the_United_States">COPD Mortality Statistics In the United States</a></li><li><a href="#COPD_Deaths_Demographics">COPD Deaths Demographics</a></li><li><a href="#COPD_Prevalence_in_the_United_States">COPD Prevalence in the United States</a></li><li><a href="#COPD_Statistics_Deaths_Worldwide">COPD Statistics — Deaths Worldwide</a></li></ul></li><li><a href="#Most_Common_Causes_of_COPD_in_Non-Smokers">Most Common Causes of COPD in Non-Smokers</a><ul><li><a href="#Poor_Lung_Development">Poor Lung Development</a></li><li><a href="#Secondhand_Smoke_SHS">Secondhand Smoke (SHS)</a></li><li><a href="#AATD_Deficiency">AATD Deficiency </a></li></ul></li><li><a href="#What_Are_the_Stages_of_COPD">What Are the Stages of COPD?</a><ul><li><a href="#How_Many_Years_of_Smoking_Does_It_Take_to_Develop_COPD">How Many Years of Smoking Does It Take to Develop COPD?</a></li></ul></li><li><a href="#Whats_The_Average_Life_Expectancy_for_People_Diagnosed_with_COPD">What’s The Average Life Expectancy for People Diagnosed with COPD?</a><ul><li><a href="#Life_Expectancy_Highest_in_Never_Smokers">Life Expectancy Highest in Never Smokers</a></li><li><a href="#COPD_Average_Life_Expectancy_Chart">COPD Average Life Expectancy Chart </a></li></ul></li><li><a href="#Whats_The_Survival_Rate_of_COPD">What’s The Survival Rate of COPD?</a></li><li><a href="#Whats_the_Annual_Cost_of_COPD">What's the Annual Cost of COPD?</a><ul><li><a href="#How_Long_Does_It_Take_to_Get_Disability_for_COPD">How Long Does It Take to Get Disability for COPD?</a></li></ul></li><li><a href="#Common_Treatments_for_COPD">Common Treatments for COPD</a><ul><li><a href="#AmoxicillinClavulanic_Acid">Amoxicillin/Clavulanic Acid</a></li><li><a href="#Corticosteroids">Corticosteroids</a></li><li><a href="#SalmeterolFluticasone_Combination">Salmeterol/Fluticasone Combination</a></li><li><a href="#Multifactorial_Intervention">Multifactorial Intervention</a></li><li><a href="#Carbocysteine">Carbocysteine</a></li></ul></li><li><a href="#Final_Thoughts_COPD_Facts_Statistics">Final Thoughts — COPD Facts &amp; Statistics</a></li></ul></div> </div> </header> <div class="col-xs-12 single--content" id="content"> <h2><span id="Report_Highlights"><strong>Report Highlights:</strong></span></h2> <ul> <li><span style="font-weight: 400;">Every year, over </span><b>150,000 Americans</b><span style="font-weight: 400;"> die of chronic obstructive pulmonary disease (COPD), which equals </span><b>one death every 4 minutes</b><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">9</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Smoking tobacco causes </span><b>75% of COPD deaths</b><span style="font-weight: 400;">, while </span><b>25%</b><span style="font-weight: 400;"> of the people diagnosed with this condition </span><b>have never smoked</b><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">9</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">People who have </span><b>never smoked</b> <b>cigarettes in the last 30 days </b><span style="font-weight: 400;">have a </span><b>67% lower COPD prevalence</b><span style="font-weight: 400;">, while </span><b>former users</b><span style="font-weight: 400;"> and </span><b>cigar users</b><span style="font-weight: 400;"> have a </span><b>43% and 54% lower prevalence</b><span style="font-weight: 400;"> of COPD, respectively [</span><span style="font-weight: 400;">37</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">In 2019, COPD was the</span><b> third principal cause</b><span style="font-weight: 400;"> of death globally at </span><b>5.8%</b><span style="font-weight: 400;">, right behind stroke and ischaemic heart disease [</span><span style="font-weight: 400;">13</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">The average age at death from COPD between 2000 and 2005 was </span><b>76.6</b> <b>years </b><span style="font-weight: 400;">compared to </span><b>72.9 years</b><span style="font-weight: 400;"> in 1980-85 [</span><span style="font-weight: 400;">4</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1"><b>7.3%</b><span style="font-weight: 400;"> of COPD patients will live </span><b>15 years after admission for worsening COPD </b><span style="font-weight: 400;">compared to </span><b>40.6%</b><span style="font-weight: 400;"> of the general population of the same age and sex [</span><span style="font-weight: 400;">46</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Hospitalized COPD patients have an </span><b>82% lower survival rate</b><span style="font-weight: 400;"> in the next 15 years after admission for worsening COPD than people in the general population [</span><span style="font-weight: 400;">46</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">COPD is more prevalent in </span><b>females at 7.1%</b><span style="font-weight: 400;"> than in </span><b>males at 5.7%</b><span style="font-weight: 400;"> because women smokers have a</span><b> 50%</b><span style="font-weight: 400;"> greater likelihood of developing COPD than men [2, </span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">]</span><span style="font-weight: 400;">.</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">According to a Danish study, it takes </span><b>25 years of smoking</b><span style="font-weight: 400;"> to develop COPD. The data shows that at least</span><b> 25% of smokers</b><span style="font-weight: 400;"> who had no COPD symptoms will develop </span><b>clinically significant COPD</b><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">23</span><span style="font-weight: 400;">].</span></li> <li style="font-weight: 400;" aria-level="1">On average, it takes<b> three to five months</b> for the patient to learn whether they <b>qualify for COPD disability</b> and an additional <b>five months</b> to receive the first payment [7].</li> </ul> <p><span style="font-weight: 400;">Chronic obstructive pulmonary disease (short: COPD) encompasses several </span><span style="font-weight: 400;">chronic respiratory diseases</span><span style="font-weight: 400;"> characterized by airflow blockage and difficulty breathing </span><span style="font-weight: 400;">[</span><span style="font-weight: 400;">28</span><span style="font-weight: 400;">]</span><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">The two main conditions that fall under the term COPD are chronic bronchitis and emphysema. Together with asthma, all these conditions (including COPD) are known as chronic lower respiratory diseases (CLRD) [</span><span style="font-weight: 400;">20</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">We’ve gathered the most interesting and helpful statistics about COPD to shed light on this condition.</span></p> <h2><span id="COPD_Prevalence_Mortality_Demographics_and_Statistics"><b>COPD Prevalence &amp; Mortality Demographics and Statistics</b></span></h2> <p><span style="font-weight: 400;">In the United States, every 46.3 deaths out of 100,000 people are attributed to COPD [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p>&nbsp;</p> <p><img decoding="async" class="alignnone wp-image-22603 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-01-7.png?_t=1672411839" alt="Call out text box saying 43.6 deaths in 100,000 people come from COPD." width="1875" height="596" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-01-7.png 1875w, https://cfah.org/wp-content/uploads/2022/12/Icons-01-7-300x95.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-01-7-1024x325.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-01-7-768x244.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-01-7-1536x488.png 1536w, https://cfah.org/wp-content/uploads/2022/12/Icons-01-7-720x229.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-01-7-105x33.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-01-7-70x22.png 70w" sizes="(max-width: 1875px) 100vw, 1875px" /></p> <p><span style="font-weight: 400;">According to the World Health Organization, 3.23 million people died of COPD in 2019 — making this condition the third leading cause of death globally [</span><span style="font-weight: 400;">8</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Millions of people around the globe die from COPD every year, </span><span style="font-weight: 400;">as this disease remains a significant global burden</span><span style="font-weight: 400;">. It’s alarming that this condition remains undiagnosed and untreated in millions more.</span></p> <h3><span id="How_Many_Deaths_Does_COPD_Cause"><strong>How Many Deaths Does COPD Cause?</strong></span></h3> <p><span style="font-weight: 400;">More than 150,000 Americans lose their lives from COPD within a year, which equals one death every 4 minutes [</span><span style="font-weight: 400;">9</span><span style="font-weight: 400;">].</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22604 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-02-7.png?_t=1672411852" alt="" width="1875" height="597" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-02-7.png 1875w, https://cfah.org/wp-content/uploads/2022/12/Icons-02-7-300x96.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-02-7-1024x326.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-02-7-768x245.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-02-7-1536x489.png 1536w, https://cfah.org/wp-content/uploads/2022/12/Icons-02-7-720x229.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-02-7-105x33.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-02-7-70x22.png 70w" sizes="(max-width: 1875px) 100vw, 1875px" /></p> <p><span style="font-weight: 400;">The total number of deaths from chronic lower respiratory diseases (CLRD) was higher in 2018 than in 2020. In 2020, 152,657 people died of CLRD compared to 2018 at 159,486, making these conditions the sixth and fourth main cause of death in the US, respectively [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22605 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-03-8.png?_t=1672411863" alt="Call out text box saying 139,585 people died every year due to COPD between 1999 and 2020. " width="1875" height="553" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-03-8.png 1875w, https://cfah.org/wp-content/uploads/2022/12/Icons-03-8-300x88.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-03-8-1024x302.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-03-8-768x227.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-03-8-1536x453.png 1536w, https://cfah.org/wp-content/uploads/2022/12/Icons-03-8-720x212.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-03-8-105x31.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-03-8-70x21.png 70w" sizes="(max-width: 1875px) 100vw, 1875px" /></p> <p><span style="font-weight: 400;">In 2017, 160,201 people died of COPD, making it the year with the most deaths from 1999 through 2020. This year is followed by 2018 with 159,486 deaths and 2019 with 156,979 deaths. Among the top five years of death from COPD are 2015, with 155,041 people, and 2016 with 154,596 people [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In 2004, 121,987 people died of COPD, making it the year with the lowest number of deaths between 1999 and 2020. With 122,009 and 123, 013 COPD deaths, 2000 and 2001 follow suit, respectively</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Compared to 1999, 28,476 more people died of COPD in 2020, which shows the increase in the number of deaths within this period [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">8,924 more people have died of COPD in 2005 than in 2000, while 7,147 more died in 2010 than 2005. In 2015, 16,961 more people lost their lives to COPD than in 2010, while fewer people (2,384) died of COPD in 2020 than in 2015</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Most (85.58%) COPD deaths occur among those aged 65 years or older with a total of 2.6 million deaths from 1999 through 2020 [5].</span></p> <p><iframe id="datawrapper-chart-9weAY" style="width: 0; min-width: 100% !important; border: none;" title="Number of COPD Deaths Overtime" src="https://datawrapper.dwcdn.net/9weAY/1/" height="500" frameborder="0" scrolling="no" aria-label="Interactive line chart" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <h3><span id="COPD_Mortality_Statistics_In_the_United_States"><b>COPD Mortality Statistics In the United States</b></span></h3> <p><span style="font-weight: 400;">COPD is a principal cause of mortality and morbidity in the United States. The average age at death from COPD in the period between 2000-05 was 76.6 years [</span><span style="font-weight: 400;">4</span><span style="font-weight: 400;">]. The main cause of COPD and COPD deaths is tobacco smoking [</span><span style="font-weight: 400;">40</span><span style="font-weight: 400;">].</span></p> <h4><strong>What’s the Average Age At Death from COPD?</strong></h4> <p><span style="font-weight: 400;">Between the 1980-85 period, the average age at death from COPD was 72.9 years, while between 2000-05, it rose to 76.6 years. The 3.7 age increase indicates that COPD patients don’t die as young as four decades ago. This may be connected to early diagnosis, prompt treatment, and a decline in tobacco smoking [</span><span style="font-weight: 400;">4</span><span style="font-weight: 400;">].</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22513 size-full" src="https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2.png?_t=1672347135" alt="Scatter plot showing an increase in the average age at death in COPD patients for 3.7 years between the 80s and 00s. " width="2798" height="1177" srcset="https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2.png 2798w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-300x126.png 300w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-1024x431.png 1024w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-768x323.png 768w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-1536x646.png 1536w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-2048x862.png 2048w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-720x303.png 720w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-1920x808.png 1920w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-105x44.png 105w, https://cfah.org/wp-content/uploads/2022/12/5-Average-Age-at-Death-from-COPD-in-the-US-2-70x29.png 70w" sizes="(max-width: 2798px) 100vw, 2798px" /></p> <p><span style="font-weight: 400;">This data comes from the Journal of Chronic Obstructive Pulmonary Disease, which states that there was an increase in the average age at COPD death for three to four years between 1980 and 2005 [</span><span style="font-weight: 400;">4</span><span style="font-weight: 400;">].</span></p> <h4><strong>What Is the Most Common Cause of Death in COPD Patients?</strong></h4> <p><span style="font-weight: 400;">Studies show that 75% of COPD deaths are attributed to cigarette smoking [</span><span style="font-weight: 400;">9</span><span style="font-weight: 400;">]. This is unsurprising as one in five smokers will develop COPD throughout their lives [</span><span style="font-weight: 400;">33</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Despite the danger COPD presents, data shows that 38% of the nearly 16 million U.S. adults with a COPD diagnosis are current smokers [</span><span style="font-weight: 400;">31</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The fact that puzzles researchers is that 25% of the people who die of COPD have never smoked in their life [</span><span style="font-weight: 400;">9</span><span style="font-weight: 400;">].</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22514 size-full" src="https://cfah.org/wp-content/uploads/2022/12/6-2.png?_t=1672347546" alt="Stacked bar showing COPD deaths in smokers (75%) and never smokers (25%)." width="2657" height="746" srcset="https://cfah.org/wp-content/uploads/2022/12/6-2.png 2657w, https://cfah.org/wp-content/uploads/2022/12/6-2-300x84.png 300w, https://cfah.org/wp-content/uploads/2022/12/6-2-1024x288.png 1024w, https://cfah.org/wp-content/uploads/2022/12/6-2-768x216.png 768w, https://cfah.org/wp-content/uploads/2022/12/6-2-1536x431.png 1536w, https://cfah.org/wp-content/uploads/2022/12/6-2-2048x575.png 2048w, https://cfah.org/wp-content/uploads/2022/12/6-2-720x202.png 720w, https://cfah.org/wp-content/uploads/2022/12/6-2-1920x539.png 1920w, https://cfah.org/wp-content/uploads/2022/12/6-2-105x29.png 105w, https://cfah.org/wp-content/uploads/2022/12/6-2-70x20.png 70w" sizes="(max-width: 2657px) 100vw, 2657px" /></p> <p><span style="font-weight: 400;">People who have never smoked have a 67% lower COPD prevalence. The prevalence of COPD is also lower in former cigarette users at 43% and in cigar users at 54% [</span><span style="font-weight: 400;">37</span><span style="font-weight: 400;">].</span></p> <p><iframe id="datawrapper-chart-HUajy" style="width: 0; min-width: 100% !important; border: none;" title="COPD Prevalence by Smoking Status" src="https://datawrapper.dwcdn.net/HUajy/2/" height="211" frameborder="0" scrolling="no" aria-label="Bar Chart" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p><span style="font-weight: 400;">Former cigarette users have a 72% higher prevalence of COPD compared to people who have never smoked cigarettes [</span><span style="font-weight: 400;">37</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">A study published in BM Pulmonary Medicine investigated the exclusive use of cigarettes within the past 30 days. It revealed that tobacco smoke is fundamental for the development and progression of COPD [</span><span style="font-weight: 400;">37</span><span style="font-weight: 400;">].</span></p> <h3><span id="COPD_Deaths_Demographics"><strong>COPD Deaths Demographics</strong></span></h3> <p><span style="font-weight: 400;">Of the 152,657 COPD deaths in 2020, women make up the most with 79,715 people. COPD deaths are also the highest among older people aged 75-79 with 25,311 and Whites with 130,947 [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <h4><strong>COPD Deaths Statistics: Male vs. Female</strong></h4> <p><span style="font-weight: 400;">More women died of COPD (79,715) than men (72,942) in 2020, says data from the Centers for Disease Control and Prevention [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The percentage of COPD deaths is higher in females at 52.22% than in males at 47.78%, but men have 9.3 lower percentage points of survival than women. Studies show that male COPD patients who are intubated are more likely to die in the long run than female patients [</span><span style="font-weight: 400;">45</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The crude death rate per 100,000 people is 47.7 for females compared to 45.0 for males</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The </span><i><span style="font-weight: 400;">crude death rate </span></i><span style="font-weight: 400;">indicates the number of COPD deaths during the year per 100,000 midyear population.</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22528 size-full" src="https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3.png?_t=1672354402" alt="USA map showing that of all states, West Virginia has the highest rate of COPD deaths (90.1), while California has the highest number of deaths (12,907). " width="2657" height="2477" srcset="https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3.png 2657w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-300x280.png 300w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-1024x955.png 1024w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-768x716.png 768w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-1536x1432.png 1536w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-2048x1909.png 2048w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-720x671.png 720w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-1920x1790.png 1920w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-105x98.png 105w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-3-70x65.png 70w" sizes="(max-width: 2657px) 100vw, 2657px" /></p> <p><span style="font-weight: 400;">Females with severe COPD have a 50% increased risk of hospitalization and a greater risk of death from respiratory complications than males. Females’ lung anatomy, low estrogen levels, and late diagnosis may be important risk factors for these, says a study published in the American Journal of Respiratory and Critical Care Medicine [</span><span style="font-weight: 400;">2</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">But, males have a historically higher exposure to smoke from cigarettes and occupational lung irritants as potential COPD risk factors for worse long-term survival [</span><span style="font-weight: 400;">45</span><span style="font-weight: 400;">]. Occupational exposure to lung irritants for COPD causes higher proportional mortality in males than females at a population attributable fraction of 10.6% and 6.1%, respectively [</span><span style="font-weight: 400;">16</span><span style="font-weight: 400;">].</span></p> <h4><strong>COPD Deaths by Age Statistics</strong></h4> <p><span style="font-weight: 400;">In 2020, most (84.31%) COPD deaths occurred among adults aged 65 years or older at a total of 128,712</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">25,311 older adults aged 75 through 79 years died of COPD in 2020. This age group also holds the highest percentage of deaths among all age groups at 16.58%. Older adults aged 80 through 84 follow with 24,052 deaths or 15.76%</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">14.61% of older adults aged 70 to 74 years died of COPD in 2020, which equals 22,307 deaths. Older adults 85 through 89 are also in the top five age groups for COPD deaths at 13.60% or 20,766 deaths, followed by 65 through 69 year olds at 16,252 deaths or 10.65%</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Both the number of COPD deaths and the percentage fall proportionally in younger adults</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">8.02% or 12,237 of COPD deaths in 2020 happened in adults 60 through 64 years, which is a difference of 4,015 deaths from the 65 through 69 age group. From there, the number of deaths notices nearly a double decline at 6,579 deaths (4.31%) in adults aged 55 through 59 years</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The lowest number of deaths in adults over 45 was in COPD patients aged 45 through 49 at 1,038 (0.68%). The 50 through 54 age group follows with 2,500 deaths or 1.64% [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">In 2020, older adults aged 80 through 84 years had the highest death rate at 372.1 per 100,000. For comparison, only 180 people aged 25 through 29 died of COPD in 2020 at a 0.8 rate per 100,000 [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><iframe id="datawrapper-chart-lEWrQ" style="width: 0; min-width: 100% !important; border: none;" title="COPD Deaths by Age Group (2020)" src="https://datawrapper.dwcdn.net/lEWrQ/12/" height="1015" frameborder="0" scrolling="no" aria-label="Table" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p>This indicates that both the number and the rate of COPD deaths are closely related to age and are the highest in older adults.</p> <h4><strong>COPD Deaths by Race Statistics</strong></h4> <p><span style="font-weight: 400;">At 130,947 out of 152,657 COPD deaths in 2020, White Americans have the highest number of deaths, percentage of deaths (85.78%), and death rates (65.3 per 100,000). Black Americans come in second with 12,361 deaths or 8.10% of all COPD deaths in 2020</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The number of deaths is lowest in American Indian and Alaska Natives (AIANs) at 861 or 0.56%. Asian Americans at 2,176 (1.43%), and Hispanics at 5,949 or 3.90% follow</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Out of all races, Hispanics have the lowest death rate at 9.7 per 100,000, while White Americans have the highest at 65.3. Despite the low number of deaths, AIANs also have a high death rate at 31.1 [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><iframe id="datawrapper-chart-mhOWz" style="width: 0; min-width: 100% !important; border: none;" title="COPD Deaths by Race (2020)" src="https://datawrapper.dwcdn.net/mhOWz/4/" height="391" frameborder="0" scrolling="no" aria-label="Table" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p>Whites are 4.1 times more likely to develop COPD than Hispanics. COPD’s prevalence in Hispanics is lower by both spirometry and clinical diagnosis at 41.6% compared to Whites at 54.2% [1].</p> <p>The exact reason for this is largely unknown, but a London study suggests that it may be due to ethnic differences in cigarette consumption and potential ethnic susceptibility to this disease [15].</p> <h4><strong>COPD Deaths by State Statistics</strong></h4> <p><span style="font-weight: 400;">At 90.1 per 100,000, West Virginia had the highest COPD death rate, while Hawaii had the lowest at 26.7, shows 2020 data from the CDC [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">West Virginia is the state with the highest percentage of tobacco use in the nation, with 23.8% of adult West Virginians being current smokers in 2022 [</span><span style="font-weight: 400;">41</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Even though West Virginia had the highest COPD death rate and California is among the five states with lowest COPD death rate (32.8 per 100,000), California had the highest number of deaths at 12,907 or 8.45% out of all US states [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">California is among the ten states with the lowest tobacco use rates, but it has the top four most polluted cities in the United States [</span><span style="font-weight: 400;">27</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Second and third in line in the number of deaths were Florida (11,791) and Texas (10,402), respectively [</span><span style="font-weight: 400;">5</span><span style="font-weight: 400;">].</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22519 size-full" src="https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2.png?_t=1672351624" alt="USA map showing that of all states, West Virginia has the highest rate of COPD deaths (90.1), while California has the highest number of deaths (12,907). " width="2657" height="2477" srcset="https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2.png 2657w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-300x280.png 300w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-1024x955.png 1024w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-768x716.png 768w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-1536x1432.png 1536w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-2048x1909.png 2048w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-720x671.png 720w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-1920x1790.png 1920w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-105x98.png 105w, https://cfah.org/wp-content/uploads/2022/12/11-COPD-Deaths-by-State-2020-2-70x65.png 70w" sizes="(max-width: 2657px) 100vw, 2657px" /></p> <h3><span id="COPD_Prevalence_in_the_United_States"><b>COPD Prevalence in the United States</b></span></h3> <p><span style="font-weight: 400;">COPD affects more than 15 million American adults, but the real number is greater because many people don’t know they have this condition [</span><span style="font-weight: 400;">35</span><span style="font-weight: 400;">].</span></p> <p>In 2021, 4.6% of adults aged 18 and over suffered from emphysema or chronic bronchitis [32].</p> <p><span style="font-weight: 400;">Data shows that more than half of the diagnosed adults are women [35</span><span style="font-weight: 400;">].</span></p> <h4><strong>COPD Prevalence Statistics: Male vs. Female </strong></h4> <p><span style="font-weight: 400;">COPD is more prevalent in females at 7.1% than in males at 5.7%. Based on CDC sample data, women also have a higher number of COPD cases (19,989 out of 233,922) compared to men (14,180 out of 202,664)</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><iframe id="datawrapper-chart-ewV3E" style="width: 0; min-width: 100% !important; border: none;" title="COPD Prevalence by Gender (2021) " src="https://datawrapper.dwcdn.net/ewV3E/6/" height="217" frameborder="0" scrolling="no" aria-label="Table" data-external="1" data-mce-fragment="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p><span style="font-weight: 400;">Biologically, women smokers are more susceptible to this disease because of the faster decline in FEV1 </span><span style="font-weight: 400;">—</span><span style="font-weight: 400;"> even if smoking fewer cigarettes than men. Studies show that females develop more severe COPD and at an earlier age compared to males (younger than 60) [</span><span style="font-weight: 400;">2</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Evidence shows that the 1960s propaganda by the tobacco industry that targeted women (and resulted in increased smoking rates) is partly to blame [</span><span style="font-weight: 400;">18</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Another reason why women suffer from COPD more than men is that they are commonly misdiagnosed. COPD has been known for decades as a man’s disease, so female smokers are more than 33% less likely to be diagnosed with COPD compared to male smokers [</span><span style="font-weight: 400;">18</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Cumulatively, women consume less tobacco than men but are more susceptible to it, resulting in a more severe, earlier-onset COPD and a faster FEV1 decline. The numbers show that women represent 80% of the nonsmoker COPD patient group, likely due to biomass fuel exposure or indoor air pollution created by poorly ventilated areas for cooking [</span><span style="font-weight: 400;">18</span><span style="font-weight: 400;">].</span></p> <p><em>Note: </em><em>The FEV1 measures how quickly the lungs are emptied after taking a maximal inhale. An excessive decline of this parameter over the course of 5 or more years is tightly correlated to the level of lung function and a predictor of morbidity and mortality. At a</em><em> normal rate</em><em>, the </em><em>FEV1 decline should be 30 ml/y </em>[44]<em>.</em></p> <h4><strong>COPD Prevalence by Age Statistics</strong></h4> <p><span style="font-weight: 400;">With 5,381 cases, the 70 to 74 age group has the highest number of people with COPD. It’s followed by the 65 to 69 group at 4,998 cases and the 60 to 64 age group at 4,826 cases</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The highest prevalence rate of COPD cases by age is in adults aged 75 to 79 at 13.8%. Adults aged 70 to 74 follow at 13.2%, and older than 80 at 12.6%</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">]. The prevalence rate of COPD significantly increases with age.</span></p> <p><span style="font-weight: 400;">Only 1.7%, or 410 people aged 18 to 24, have ever been told they had COPD, which remains the age group with the lowest prevalence and lowest number of cases. The 25 to 29 age group and the 30 to 34 age group follow with 464 (2.3%) and 632 (3.0%) cases, respectively [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><iframe id="datawrapper-chart-b3lNX" style="width: 0; min-width: 100% !important; border: none;" title="COPD Prevalence by Age Group (2021)" src="https://datawrapper.dwcdn.net/b3lNX/5/" height="635" frameborder="0" scrolling="no" aria-label="Table" data-external="1" data-mce-fragment="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p><span style="font-weight: 400;">Smokers are most likely to suffer from COPD, but this condition is most common in people older than 40 who are smokers or have smoked earlier in life [</span><span style="font-weight: 400;">34</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">While young adults can, but rarely, develop COPD, the first symptoms appear in adults who are at least in their forties [</span><span style="font-weight: 400;">10</span><span style="font-weight: 400;">].</span></p> <h4><strong>COPD Prevalence by Race Statistics</strong></h4> <p><strong><span style="font-weight: 400;">COPD affects American Indian and Alaskan Natives (AIAN) the most at 10.6% or 720 cases out of 7,214 people. At 7.9% or 901 and 7.6% or 27,865 cases, Multiracial Americans and White Americans, respectively, follow</span> </strong>[3].</p> <p><span style="font-weight: 400;">Black Americans are the fourth most commonly affected race from COPD based on CDC’s sample size at 6.3%</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">White Americans have the highest number of COPD cases at 27,865 out of 330,730 people. Black Americans come in second at 2,386 COPD cases out of 32,946 people. Hispanics are third with 1,566 cases out of 38,230 people</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><iframe id="datawrapper-chart-ijQ2S" style="width: 0; min-width: 100% !important; border: none;" title="COPD Prevalence by Race (2021) " src="https://datawrapper.dwcdn.net/ijQ2S/2/" height="484" frameborder="0" scrolling="no" aria-label="Table" data-external="1" data-mce-fragment="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p>This may be connected to high smoking rates among AIANs at 27.1% compared to Asians and Hispanics at 8.0% each, and the overall US population at 12.5% or 30.8 million people [30].</p> <p>In 2020, American Indians and Alaska Natives (AIANs) had the highest smoking prevalence compared to other races in the US [30].</p> <p>This group tends to hold sacred tobacco ceremonials, and use tobacco for religious and medical uses. Also, tobacco sold in their lands is not taxed, so that’s another contributor to increased tobacco smoking rates [30].</p> <h4><strong>COPD Prevalence by State Statistics</strong></h4> <p><span style="font-weight: 400;">Based on CDC’s sample size, New York has the highest number of COPD cases at 3,364. Ohio and Kansas follow at 1,500 and 1,310 cases, respectively</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">]. </span></p> <p><span style="font-weight: 400;">The states with the lowest number of COPD cases are Illinois with 211, Nevada with 255, and Delaware with 277</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">West Virginia has the highest prevalence rate by state. Out of 6,711 West Virginians, 13.1% or 951 have been told they had COPD at any time of their lives, followed by 10.9% or 699 out of 5,395 Kentuckians</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">]. </span></p> <p><span style="font-weight: 400;">Tennessee and Arkansas are also among the top five states with the highest COPD prevalence by state. 10.4% or 529 people out of 4,763 Tennesseans and 9.6% or 646 people out of 5,349 Arkansans have been told they had COPD at any time in their lives [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">The state with the lowest COPD prevalence by cases is Hawaii, with 3.5% or 346 cases out of 7,768 people, followed by Utah at 4.3% or 543 cases out of 10,546</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">3</span><span style="font-weight: 400;">].</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22522 size-full" src="https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3.png?_t=1672352925" alt="USA map showing COPD rates and number of cases (based on sample size) per state." width="2657" height="2730" srcset="https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3.png 2657w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-292x300.png 292w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-997x1024.png 997w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-768x789.png 768w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-1495x1536.png 1495w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-1993x2048.png 1993w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-720x740.png 720w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-1920x1973.png 1920w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-105x108.png 105w, https://cfah.org/wp-content/uploads/2022/12/20-COPD-Prevalence-by-State-2020-3-70x72.png 70w" sizes="(max-width: 2657px) 100vw, 2657px" /></p> <h3><span id="COPD_Statistics_Deaths_Worldwide"><b>COPD Statistics </b><b>—</b><b> Deaths Worldwide</b></span></h3> <p><span style="font-weight: 400;">In 2019, 3.23 million people, or 5.8% of global deaths were attributed to COPD. This disease was the third leading cause of death worldwide after ischaemic heart disease with 8.89 million deaths (16.0%) and stroke with 6.19 million (11.2%) [</span><span style="font-weight: 400;">12</span><span style="font-weight: 400;">] [</span><span style="font-weight: 400;">13</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Global and regional estimates show that lower respiratory infections, neonatal conditions, and Alzheimer's were among the ten leading causes of death globally in that year [</span><span style="font-weight: 400;">13</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Diabetes mellitus (1.5 million) and kidney disease (1.33 million) were at the bottom of the list of leading causes of global deaths</span><span style="font-weight: 400;"> [</span><span style="font-weight: 400;">12</span><span style="font-weight: 400;">].</span></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22523 size-full" src="https://cfah.org/wp-content/uploads/2022/12/table-5.png?_t=1672353092" alt="Table showing that COPD is the third leading cause of death worldwide, affecting 5.8% of the population or 3.23 million people." width="2657" height="4145" srcset="https://cfah.org/wp-content/uploads/2022/12/table-5.png 2657w, https://cfah.org/wp-content/uploads/2022/12/table-5-192x300.png 192w, https://cfah.org/wp-content/uploads/2022/12/table-5-656x1024.png 656w, https://cfah.org/wp-content/uploads/2022/12/table-5-768x1198.png 768w, https://cfah.org/wp-content/uploads/2022/12/table-5-985x1536.png 985w, https://cfah.org/wp-content/uploads/2022/12/table-5-1313x2048.png 1313w, https://cfah.org/wp-content/uploads/2022/12/table-5-720x1123.png 720w, https://cfah.org/wp-content/uploads/2022/12/table-5-1920x2995.png 1920w, https://cfah.org/wp-content/uploads/2022/12/table-5-105x164.png 105w, https://cfah.org/wp-content/uploads/2022/12/table-5-70x109.png 70w" sizes="(max-width: 2657px) 100vw, 2657px" /></p> <h2><span id="Most_Common_Causes_of_COPD_in_Non-Smokers"><strong>Most Common Causes of COPD in Non-Smokers</strong></span></h2> <p><span style="font-weight: 400;">53.9% out of 200 non-smoking COPD patients developed this condition due to exposure to biomass smoke, says an Indian study. Treated pulmonary tuberculosis was a significant risk factor in 32.7% of the non-smoking patients and long-standing asthma in 14.2% of the patients [</span><span style="font-weight: 400;">38</span><span style="font-weight: 400;">].</span></p> <p><span style="font-weight: 400;">Ten percent (10%)</span> of the non-smoking patients developed COPD due to several risk factors, including occupational exposure, outdoor air pollution exposure, and lower respiratory tract infection in childhood [38].</p> <p>Up to 30% of people with COPD are non-smokers and have never smoked in their lives [35]. Here are a few more answers to why non-smokers develop COPD.</p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22606 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-08-9.png?_t=1672411890" alt="Call out text box saying that 30% of people who develop COPD don’t smoke and have never smoked. " width="1875" height="562" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-08-9.png 1875w, https://cfah.org/wp-content/uploads/2022/12/Icons-08-9-300x90.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-08-9-1024x307.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-08-9-768x230.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-08-9-1536x460.png 1536w, https://cfah.org/wp-content/uploads/2022/12/Icons-08-9-720x216.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-08-9-105x31.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-08-9-70x21.png 70w" sizes="(max-width: 1875px) 100vw, 1875px" /></p> <h3><span id="Poor_Lung_Development"><strong>Poor Lung Development</strong></span></h3> <p><span style="font-weight: 400;">Out of 200 non-smoking COPD patients, 28.9%</span><span style="font-weight: 400;"> suffered more respiratory infections during childhood compared to 18.7% of smokers, shows data from a Korean multicenter cohort </span>[6].</p> <p><iframe id="datawrapper-chart-zM1am" style="width: 0; min-width: 100% !important; border: none;" title="What Causes COPD in Non Smokers? " src="https://datawrapper.dwcdn.net/zM1am/2/" height="323" frameborder="0" scrolling="no" aria-label="Bar Chart" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p>According to researchers, the reason why people who never smoked develop COPD may be improper lung development [24]. Research has shown that even at an early age, older adults with COPD appear to have experienced low lung function. <span style="font-weight: 400;">Although unconfirmed, </span><span style="font-weight: 400;">frequent respiratory infections</span><span style="font-weight: 400;"> during childhood may explain why non-smokers have experienced low function at an early age</span> [6].</p> <p>At 57.5% out of 2,477 patients, females comprise a higher proportion of non-smoking COPD patients compared to smoking COPD patients at 3.3% [6]. A strong risk factor for COPD in non-smokers is small airways relative to lung size, says a 2020 JAMA study [24].</p> <p>Females have relatively smaller airways than males, but the reasons why females with small airways have a greater susceptibility to COPD is unknown. One theory is that the concentration of tobacco smoke may be greater per unit area in a smaller airway surface, but this remains to be investigated [2].</p> <h3><span id="Secondhand_Smoke_SHS">Secondhand <strong>Smoke (SHS)</strong></span></h3> <p>Among 334 COPD patients who don’t actively smoke, 66.65% were exposed to short-term and 34.91% to medium-term secondhand smoke, showed a five-year survey by the US National Health and Nutrition [14].</p> <p>The short term SHS exposure in COPD patients who don’t actively smoke was 3.73 times higher compared to the general population of adult nonsmokers older than 40 [14].</p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22607 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-09-8.png?_t=1672411903" alt="Call out text box saying nonsmokers have been 3.73 times more exposed to secondhand smoke compared to the general population of nonsmokers. " width="1875" height="563" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-09-8.png 1875w, https://cfah.org/wp-content/uploads/2022/12/Icons-09-8-300x90.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-09-8-1024x307.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-09-8-768x231.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-09-8-1536x461.png 1536w, https://cfah.org/wp-content/uploads/2022/12/Icons-09-8-720x216.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-09-8-105x32.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-09-8-70x21.png 70w" sizes="(max-width: 1875px) 100vw, 1875px" /></p> <p>A significant contributor to COPD in people who don’t smoke and have never smoked is long-term exposure to secondhand smoke [31].</p> <p>In addition, people who have been exposed to secondhand smoke during childhood and teenage years are at a greater risk of developing COPD in their adult years. This is because exposure to secondhand smoke in children and teens can slow the process of lung growth and development [31].</p> <h3><span id="AATD_Deficiency"><strong>AATD Deficiency </strong></span></h3> <p>One to four percent of COPD patients have a rare, hereditary genetic condition known as alpha-1-antitrypsin deficiency (A1AD) [26]. According to the British Lung Foundation, having AATD increases the likelihood of the patient developing COPD [48].</p> <p>Research shows that AATD remains underdiagnosed in COPD patients, despite recommendations to check for it in these patients [25].</p> <p>COPD patients 40 years of age or older have an adjusted rate of AATD of 0.83% [25].</p> <h2><span id="What_Are_the_Stages_of_COPD"><strong>What Are the Stages of COPD?</strong></span></h2> <p>The stages of COPD are based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD) Guidelines. The GOLD guidelines put COPD development in four stages, including mild, moderate, severe, and very severe [43].</p> <p>At Stage I of the disease (mild), the person may experience no symptoms but typically has difficulty breathing when walking the stairs. Their airflow is 80% of the normal airflow [42].</p> <p><span style="font-weight: 400;">At Stage II, or the moderate stage, the person experiences symptoms like </span><span style="font-weight: 400;">chronic cough, breathlessness, or wheezing</span><span style="font-weight: 400;"> and needs breaks to catch their breath. Their airflow is within the 50% to 79% range compared to normal levels</span> [42].</p> <p>At Stage III or the severe stage, the person experiences worsening symptoms. The shortness of breath is greater, and further exacerbations affect the person’s quality of life and may lead to hospitalization. Their airflow remains within the 30% to 50% range of normal levels [42].</p> <p>At Stage IV, or the very severe stage, the situation becomes alarming because the person’s airflow is less than 30% compared to normal levels. The person experiences severe airflow limitation, and further exacerbations can be life-threatening [42].</p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-21107 size-full" src="https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1.png?_t=1670285102" alt="Table showing the connection between the FEV1/FVC ratio and the four stages of COPD." width="2657" height="1673" srcset="https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1.png 2657w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-300x189.png 300w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-1024x645.png 1024w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-768x484.png 768w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-1536x967.png 1536w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-2048x1290.png 2048w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-720x453.png 720w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-1920x1209.png 1920w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-105x66.png 105w, https://cfah.org/wp-content/uploads/2022/12/15-Stages-of-COPD-1-70x44.png 70w" sizes="(max-width: 2657px) 100vw, 2657px" /></p> <p>Physicians use these four stages to determine the severity of COPD in the patient and help pair them with the right treatment for their stage [43].</p> <p>The entire classification is based on two parameters: Forced vital capacity (FVC) and Forced expiratory volume (FEV1) [43].</p> <p>The FVC parameter measures the largest amount of air the patient can breathe out after taking the deepest breath. The FEV1 parameter measures how much air the patient can exhale from the lungs in 1 second [43].</p> <p>Every patient has an individual predicted FEV1 value. Once calculated, the doctor compares the predicted value to the actual FEV1 score and its ratio to FVC [43].</p> <h3><span id="How_Many_Years_of_Smoking_Does_It_Take_to_Develop_COPD"><strong>How Many Years of Smoking Does It Take to Develop COPD?</strong></span></h3> <p>After 25 years, 30-40% of smokers will develop any COPD, while at least 25% of completely healthy smokers will develop COPD described as clinically significant [23].</p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22608 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-04-5.png?_t=1672411919" alt="Call out text box saying the percentage of smokers that will develop any COPD is 30-40%." width="1875" height="554" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-04-5.png 1875w, https://cfah.org/wp-content/uploads/2022/12/Icons-04-5-300x89.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-04-5-1024x303.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-04-5-768x227.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-04-5-1536x454.png 1536w, https://cfah.org/wp-content/uploads/2022/12/Icons-04-5-720x213.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-04-5-105x31.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-04-5-70x21.png 70w" sizes="(max-width: 1875px) 100vw, 1875px" /></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22609 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-05-5.png?_t=1672411932" alt="Call out text box saying the percentage of healthy smokers that will develop clinically significant COPD is 25%." width="1875" height="563" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-05-5.png 1875w, https://cfah.org/wp-content/uploads/2022/12/Icons-05-5-300x90.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-05-5-1024x307.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-05-5-768x231.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-05-5-1536x461.png 1536w, https://cfah.org/wp-content/uploads/2022/12/Icons-05-5-720x216.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-05-5-105x32.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-05-5-70x21.png 70w" sizes="(max-width: 1875px) 100vw, 1875px" /></p> <p>The data came from a Dutch study that followed men and women who smoked (but had normal lung function) for 25 years that concluded that the longer people smoked, the greater the risk of developing COPD [23].</p> <h2><span id="Whats_The_Average_Life_Expectancy_for_People_Diagnosed_with_COPD"><strong>What’s The Average Life Expectancy for People Diagnosed with COPD?</strong></span></h2> <p>The average life expectancy in relatively healthy 65-year-old Caucasian males with COPD is 17.4 years at Stage 1 of the disease and 12.5 years at Stage 3 or 4 [39].</p> <p>Relatively healthy 65-year-old Caucasian females with COPD have an average life expectancy of 19.9 years at Stage 1 of the disease and 14.5 years at Stage 3 or 4 [39].</p> <p>In conclusion, females diagnosed with COPD have a higher average life expectancy than males [39].</p> <p>Data shows that people diagnosed with COPD who continue to smoke have the lowest average life expectancy [39].</p> <p>Current male smokers have the lowest average life expectancy of 8.5 years at Stage 3 or 4 of the disease, while current female smokers have an average life expectancy of 11.3 years at the same stage [39].</p> <h3><span id="Life_Expectancy_Highest_in_Never_Smokers"><strong>Life Expectancy Highest in Never Smokers</strong></span></h3> <p>In never smokers, there’s a tiny drop in average life expectancy by 0.7 and 1.3 years at stages 2 and 3 of COPD, respectively [39].</p> <p>Compared to smokers, people who have never smoked but were diagnosed with COPD noticed a moderate decline in life expectancy. Current and former smokers experience a significant reduction in life expectancy from COPD [39].</p> <p><iframe id="datawrapper-chart-Rfwya" style="width: 0; min-width: 100% !important; border: none;" title="Average Life Expectancy in Never Smokers" src="https://datawrapper.dwcdn.net/Rfwya/4/" height="388" frameborder="0" scrolling="no" aria-label="Table" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <h3><span id="COPD_Average_Life_Expectancy_Chart"><strong>COPD Average Life Expectancy Chart </strong></span></h3> <p>The average life expectancy in people who never smoke is higher than in people diagnosed with COPD who are current and former smokers [39].</p> <ul> <li>Compared to never smokers, 65-year old current male and female smokers diagnosed with COPD have a reduced life expectancy of 0.3 and 0.2 years at stage 1, respectively. At stage 2, life expectancy is reduced by 2.2 years in both male and female current smokers. At stage 3 or 4, the life expectancy is greatly reduced compared to never smokers at 5.8 years in current male smokers and 6.1 years in current female smokers.</li> <li>Former male smokers have a reduced life expectancy of 1.4 years and 5.6 years for Stages 2, and 3 or 4, respectively.</li> <li>Former female smokers have a reduced life expectancy of 2 and 6.3 years for stages 2, and 3 or 4, respectively.</li> </ul> <p>In addition to the reduction in life expectancy of COPD, current smokers also lose an additional 3.5 years of their lives due to smoking [39].</p> <p><iframe id="datawrapper-chart-V6nmM" style="width: 0; min-width: 100% !important; border: none;" title="COPD Average Life Expectancy in Males " src="https://datawrapper.dwcdn.net/V6nmM/4/" height="352" frameborder="0" scrolling="no" aria-label="Table" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p><iframe id="datawrapper-chart-6RQlx" style="width: 0; min-width: 100% !important; border: none;" title="COPD Average Life Expectancy in Females" src="https://datawrapper.dwcdn.net/6RQlx/1/" height="369" frameborder="0" scrolling="no" aria-label="Table" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <h2><span id="Whats_The_Survival_Rate_of_COPD"><strong>What’s The Survival Rate of COPD?</strong></span></h2> <p>Hospitalized COPD patients are 82% less likely to survive within the next 15 years compared to the general population [46].</p> <p>Patients who experience worsening COPD are 7.3% likely to survive the next 15 years compared to the general population at 40.6% [46].</p> <p>The survival rate in COPD patients depends on the GOLD stage of the disease [46].</p> <p>COPD patients in the GOLD I stage have a 15-year survival of 24.0% compared to 11.1% and 5.3% survival at GOLD stages II and III, respectively [46].</p> <p><iframe id="datawrapper-chart-b2iWr" style="width: 0; min-width: 100% !important; border: none;" title="15-Year Survival Rate At Different COPD Stages" src="https://datawrapper.dwcdn.net/b2iWr/1/" height="275" frameborder="0" scrolling="no" aria-label="Bar Chart" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p>43.7% of patients will survive the 5-year mark after COPD exacerbation, and 19.9% will survive a decade compared to 57.2% of the general population [46].</p> <p>COPD patients have a reduced overall 15-year survival after diagnosis at an early stage and an even lower survival after hospitalization and exacerbation of symptoms [46].</p> <p><iframe id="datawrapper-chart-Qy7iO" style="width: 0; min-width: 100% !important; border: none;" title="Survival Rate of Hospitalized COPD Patients vs. General Population " src="https://datawrapper.dwcdn.net/Qy7iO/1/" height="500" frameborder="0" scrolling="no" aria-label="Grouped Column Chart" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p>This data is based on a study published in Respiratory Medicine that studied the mortality risks of people diagnosed with COPD — including hospitalized COPD patients versus subjects from the general population [46].</p> <p>When undergoing non-invasive ventilation (NIV) treatment, women showed a survival tendency at a survival rate of 25.7%, compared to men at 19.2% [45].</p> <p><iframe id="datawrapper-chart-v8bpM" style="width: 0; min-width: 100% !important; border: none;" title="COPD Survival After Intubation (Men vs. Women)" src="https://datawrapper.dwcdn.net/v8bpM/1/" height="180" frameborder="0" scrolling="no" aria-label="Bar Chart" data-external="1"></iframe><script type="text/javascript">!function(){"use strict";window.addEventListener("message",(function(e){if(void 0!==e.data["datawrapper-height"]){var t=document.querySelectorAll("iframe");for(var a in e.data["datawrapper-height"])for(var r=0;r<t.length;r++){if(t[r].contentWindow===e.source)t[r].style.height=e.data["datawrapper-height"][a]+"px"}}}))}(); </script></p> <p>A study published in the International Journal of Chronic Obstructive Pulmonary Disease treated patients with non-invasive ventilation (NIV) for acute respiratory failure for the first time. The study was conducted at a university hospital in Denmark on 253 patients at a median age of 72 years [45].</p> <p>In general, patients with acute respiratory failure don’t leave long after receiving NIV. This study noted a 30-day mortality rate of 29.3% and a survival rate of 23.7% [45].</p> <h2><span id="Whats_the_Annual_Cost_of_COPD"><strong>What's the Annual Cost of COPD?</strong></span></h2> <p>The US spent an estimated $49 billion in 2020, an increase from 2010s $32.1 billion. It's a costly condition, especially due to the high rate of hospitalization among older adults over 65 [29].</p> <p>51% of the annual 2010 COPD costs went to Medicare, and 18% were covered by private insurance [29]. The annual cost of COPD was three times higher in patients with severe COPD ($18,070) compared to patients with mild COPD ($5,945) [19].</p> <p>In 2010, this condition caused a loss of 16.4 million days of work at the cost of $3.9 billion [29].</p> <p><span style="font-weight: 400;">COPD is expensive, but luckily, the Social Security Administration (SSA) considers it a disability. If you’re not able to work due to advanced COPD, the SSA has a few assistance programs to help with the payments. Severe enough stages of COPD that don’t allow you to work for at least 12 months mean you’ll likely qualify for disability [</span><span style="font-weight: 400;">7</span><span style="font-weight: 400;">].</span></p> <h3><span id="How_Long_Does_It_Take_to_Get_Disability_for_COPD"><strong>How Long Does It Take to Get Disability for COPD?</strong></span></h3> <p>On average, it takes three to five months to find out whether the person qualifies for a disability for COPD. After getting approved, it takes another five months until the person receives their first disability benefit payment [7].</p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22507 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-06-6.png?_t=1672344765" alt="Call out text box saying it takes another 5 months to receive the first disability payment after waiting 3 to 5 months to know whether the patient qualifies for it. " width="1466" height="725" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-06-6.png 1466w, https://cfah.org/wp-content/uploads/2022/12/Icons-06-6-300x148.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-06-6-1024x506.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-06-6-768x380.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-06-6-720x356.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-06-6-105x52.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-06-6-70x35.png 70w" sizes="(max-width: 1466px) 100vw, 1466px" /></p> <p><img loading="lazy" decoding="async" class="alignnone wp-image-22508 size-full" src="https://cfah.org/wp-content/uploads/2022/12/Icons-07-6.png?_t=1672344798" alt="Call out text box saying it takes another 5 months to receive the first disability payment after waiting 3 to 5 months to know whether the patient qualifies for it. " width="1466" height="720" srcset="https://cfah.org/wp-content/uploads/2022/12/Icons-07-6.png 1466w, https://cfah.org/wp-content/uploads/2022/12/Icons-07-6-300x147.png 300w, https://cfah.org/wp-content/uploads/2022/12/Icons-07-6-1024x503.png 1024w, https://cfah.org/wp-content/uploads/2022/12/Icons-07-6-768x377.png 768w, https://cfah.org/wp-content/uploads/2022/12/Icons-07-6-720x354.png 720w, https://cfah.org/wp-content/uploads/2022/12/Icons-07-6-105x52.png 105w, https://cfah.org/wp-content/uploads/2022/12/Icons-07-6-70x34.png 70w" sizes="(max-width: 1466px) 100vw, 1466px" /></p> <h2><span id="Common_Treatments_for_COPD"><strong>Common Treatments for COPD</strong></span></h2> <p>While there’s no proven cure for COPD, several treatment options have shown more or less effective in treating this condition.</p> <h3><span id="AmoxicillinClavulanic_Acid"><strong>Amoxicillin/Clavulanic Acid</strong></span></h3> <p>74.1% or 117 patients with nonsevere worsening of mild to moderate COPD improved on a combination of amoxicillin and clavulanic acid compared to placebo at 59.9% or 91 patients [22].</p> <p>The patients who participated in this multicenter trial took a dosage of 500/125 mg amoxicillin/clavulanic acid three times a day for eight days and noticed a prolonged time between the last and the next interval of acute exacerbation of mild to moderate COPD (AECOPD) [22].</p> <h3><span id="Corticosteroids"><strong>Corticosteroids</strong></span></h3> <p><span style="font-weight: 400;">Four-week treatment</span><span style="font-weight: 400;"> with a high dose of oral steroids (over 30 mg) improves lung function in some COPD patients by up to 20%</span> [17].</p> <p>The researchers noted a significant improvement in patients’ FEV1 after two weeks of this treatment. However, they concluded that such high doses of corticosteroids are unsustainable in the long run due to the harm they do to the body [47].</p> <h3><span id="SalmeterolFluticasone_Combination"><strong>Salmeterol/Fluticasone Combination</strong></span></h3> <p>A salmeterol/fluticasone blend reduced the exacerbations in moderate and severe COPD cases but there was still a 64% increase in the risk of developing pneumonia compared to placebo [11].</p> <p>The researchers have concluded that an extra case of pneumonia will develop for every 31 patients undergoing this therapy over a year [11].</p> <p>In an attempt to improve COPD treatment and reduce the appearance of pneumonia as an adverse event, researchers studied the impact of a corticosteroid combination. The patients took part in a three year study and were treated with fluticasone alone or a combination of salmeterol and fluticasone [11].</p> <h3><span id="Multifactorial_Intervention"><strong>Multifactorial Intervention</strong></span></h3> <p>56.8% out of 146 patients diagnosed with COPD had reduced mobility impairment and 23.7% experienced increased cognition after a multifactorial intervention. The trial consisted of 91.8% male patients at a mean age of 69.8 years [21].</p> <p>A study published in BM Pulmonary Medicine evaluated the effectiveness of a multifactorial intervention in COPD patients with scheduled inhalation therapy. This intervention included multiple components such as [21]:</p> <ul> <li aria-level="1">Information on COPD</li> <li aria-level="1">Training in inhalation techniques</li> <li aria-level="1">Audio-visual materials</li> <li aria-level="1">Dose reminders</li> <li aria-level="1">Motivational aspects</li> </ul> <h3><span id="Carbocysteine"><strong>Carbocysteine</strong></span></h3> <p>Carbocysteine therapy decreases acute exacerbations in patients with COPD by 24% compared to placebo. The participants of the study took 1500 mg of this mucolytic for a year [36].</p> <h2><span id="Final_Thoughts_COPD_Facts_Statistics">Final Thoughts — COPD Facts &amp; Statistics</span></h2> <p>Chronic obstructive pulmonary disease (COPD) affects nearly 16 million Americans and is the cause of over 150,000 deaths per year. Smoking is the root cause of COPD, with cigarette smoking causing about 75% or nearly 8 out of 10 deaths.</p> <p>Adults 75 and older have the highest number and rate of COPD deaths. Only 7.3% of the patients diagnosed with COPD will survive the next 15 years after admission for worsening COPD.</p> <p>Once hospitalized, COPD patients at Stage I have a 24% chance of survival within the next 15 years compared to patients at Stage III at 5.3%. Treating chronic pulmonary obstructive disease is costly and amounts to 16.4 million days of total absenteeism.</p> <p><strong>References</strong></p> <ol> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Aiyer, A., Surani, S., Aguillar, R., Sharma, M., Ali, M., &amp; Varon, J. (2020). Ethnic Variance in Prevalence of COPD among Smokers in a Real World Setting. </span><i><span style="font-weight: 400;">The Open Respiratory Medicine Journal</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">14</span></i><span style="font-weight: 400;">, 93–98. [</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931151/" target="_blank" rel="nofollow noopener"><span style="font-weight: 400;">1</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Barnes, P. J. (2016). Sex Differences in Chronic Obstructive Pulmonary Disease Mechanisms. </span><i><span style="font-weight: 400;">American Journal of Respiratory and Critical Care Medicine</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">193</span></i><span style="font-weight: 400;">(8), 813–814. [</span><a href="https://doi.org/10.1164/rccm.201512-2379ED" target="_blank" rel="nofollow noopener"><span style="font-weight: 400;">2</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;" aria-level="1"><i><span style="font-weight: 400;">Behavioral Risk Factor Surveillance System</span></i><span style="font-weight: 400;">. (2022). Centers for Disease Control and Prevention. [</span><a href="https://www.cdc.gov/brfss/index.html" target="_blank" rel="nofollow noopener"><span style="font-weight: 400;">3</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Brown, D. W., Croft, J. B., Greenlund, K. J., &amp; Giles, W. H. (2009). Average Age at Death from COPD in the United States: 1980–85, 1990–95, 2000–05. </span><i><span style="font-weight: 400;">COPD: Journal of Chronic Obstructive Pulmonary Disease</span></i><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">6</span></i><span style="font-weight: 400;">(3), 152–154. [</span><a href="https://doi.org/10.1080/15412550902918428" target="_blank" rel="nofollow noopener"><span style="font-weight: 400;">4</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;" aria-level="1"><i><span style="font-weight: 400;">CDC Wonder</span></i><span style="font-weight: 400;">. (2022). Centers for Disease Control and Prevention. [</span><a href="https://wonder.cdc.gov/" target="_blank" rel="nofollow noopener"><span style="font-weight: 400;">5</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Choi, J. Y., Kim, J. W., Kim, Y. H., Yoo, K. H., Jung, K. S., Lee, J. H., Um, S. J., Lee, W. Y., Park, D., &amp; Yoon, H. K. (2022). 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[</span><a href="https://pubmed.ncbi.nlm.nih.gov/16034972/" target="_blank" rel="nofollow noopener"><span style="font-weight: 400;">47</span></a><span style="font-weight: 400;">]</span></li> <li style="font-weight: 400;" aria-level="1"><i>What is A1ATD?</i> (2013). Asthma and Lung UK. [<a href="https://www.blf.org.uk/support-for-you/alpha-1-antitrypsin-deficiency/what-is-it" target="_blank" rel="nofollow noopener">48</a>]</li> </ol> </div> <footer class="col-xs-12 single--footer"> <div class="single--author row"> <div class="col-xs-12 col-sm-3 col-0 author--avatar"> <a href="https://www.cfah.org/about-us/"> <img alt='' src='https://cfah.org/wp-content/uploads/2020/06/nina-julia-150x150.jpg' class='avatar avatar-96' height='96' width='96' /> </a> </div> <div class="col-xs-12 col-sm-9 col-0 author--meta"> <div class="author--meta-name"> <h5> <a href="https://www.cfah.org/about-us/">Nina Julia</a> </h5> </div> <div class="author--meta-description"> <p>Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.</p> </div> </div> </div> </footer> </article> <aside class="col-xs-12 col-sm-4 single--sidebar"> <div class="sidebar--widget"><div class="sidebar--title"><h5>Table of Contents</h5></div><ul class="toc_widget_list no_bullets"><li><a href="#Report_Highlights">Report Highlights:</a></li><li><a href="#COPD_Prevalence_Mortality_Demographics_and_Statistics">COPD Prevalence &amp; Mortality Demographics and Statistics</a><ul><li><a href="#How_Many_Deaths_Does_COPD_Cause">How Many Deaths Does COPD Cause?</a></li><li><a href="#COPD_Mortality_Statistics_In_the_United_States">COPD Mortality Statistics In the United States</a></li><li><a href="#COPD_Deaths_Demographics">COPD Deaths Demographics</a></li><li><a href="#COPD_Prevalence_in_the_United_States">COPD Prevalence in the United States</a></li><li><a href="#COPD_Statistics_Deaths_Worldwide">COPD Statistics — Deaths Worldwide</a></li></ul></li><li><a href="#Most_Common_Causes_of_COPD_in_Non-Smokers">Most Common Causes of COPD in Non-Smokers</a><ul><li><a href="#Poor_Lung_Development">Poor Lung Development</a></li><li><a href="#Secondhand_Smoke_SHS">Secondhand Smoke (SHS)</a></li><li><a href="#AATD_Deficiency">AATD Deficiency </a></li></ul></li><li><a href="#What_Are_the_Stages_of_COPD">What Are the Stages of COPD?</a><ul><li><a href="#How_Many_Years_of_Smoking_Does_It_Take_to_Develop_COPD">How Many Years of Smoking Does It Take to Develop COPD?</a></li></ul></li><li><a href="#Whats_The_Average_Life_Expectancy_for_People_Diagnosed_with_COPD">What’s The Average Life Expectancy for People Diagnosed with COPD?</a><ul><li><a href="#Life_Expectancy_Highest_in_Never_Smokers">Life Expectancy Highest in Never Smokers</a></li><li><a href="#COPD_Average_Life_Expectancy_Chart">COPD Average Life Expectancy Chart </a></li></ul></li><li><a href="#Whats_The_Survival_Rate_of_COPD">What’s The Survival Rate of COPD?</a></li><li><a href="#Whats_the_Annual_Cost_of_COPD">What's the Annual Cost of COPD?</a><ul><li><a href="#How_Long_Does_It_Take_to_Get_Disability_for_COPD">How Long Does It Take to Get Disability for COPD?</a></li></ul></li><li><a href="#Common_Treatments_for_COPD">Common Treatments for COPD</a><ul><li><a href="#AmoxicillinClavulanic_Acid">Amoxicillin/Clavulanic Acid</a></li><li><a href="#Corticosteroids">Corticosteroids</a></li><li><a href="#SalmeterolFluticasone_Combination">Salmeterol/Fluticasone Combination</a></li><li><a href="#Multifactorial_Intervention">Multifactorial Intervention</a></li><li><a href="#Carbocysteine">Carbocysteine</a></li></ul></li><li><a href="#Final_Thoughts_COPD_Facts_Statistics">Final Thoughts — COPD Facts &amp; Statistics</a></li></ul></div> </aside> </div> </div> </div> <footer id="footer"> <div class="container row between-xs start-xs f"> <div class="col-xs-12 col-md-4 f-logo"> <a href="https://cfah.org" class="logo" aria-label="CFAH"> <img width="70" height="28" src="https://cfah.org/wp-content/uploads/2021/07/lg_cfah-white.svg" class="attachment-cfah_logo_footer size-cfah_logo_footer" alt="" decoding="async" loading="lazy" /> </a> <div class="f-excerpt"> <p>We are a team of experts committed to promoting health &amp; wellness through education, support, and awareness.</p> </div> </div> <div class="col-xs-12 col-md-5 col-0 f-menus row"> <div class="f-menu col-xs-6 col-sm start-xs "> <h5>CBD BUYING GUIDES</h5> <div class="content"> <ul> <li><a href="/best-cbd-oil/">Best CBD Oil</a></li> <li><a href="/best-cbd-oil-for-anxiety/">Best CBD Oil for Anxiety</a></li> <li><a href="/best-cbd-oil-for-sleep/">Best CBD Oil for Sleep</a></li> <li><a href="/cbd-oil-for-arthritis/">Best CBD Oil for Arthritis</a></li> <li><a href="/buy-cbd-oil-near-me/">CBD Oil Near Me</a></li> </ul> </div> </div> <div class="f-menu col-xs-6 col-sm start-xs last"> <h5>NAVIGATION</h5> <div class="content"> <ul> <li><a href="/about-us/">About</a></li> <li><a href="/contact-us/">Contact</a></li> <li><a href="/terms/" rel="nofollow">Terms of Use</a></li> <li><a href="/privacy-policy/" rel="nofollow">Privacy</a></li> <li><a href="/disclaimer/" rel="nofollow">Disclaimer</a></li> </ul> </div> </div> </div> <div class="col-xs-12 col-md-3 f-socials"> <h5>FOLLOW CFAH</h5> <a href="https://www.facebook.com/cfahorg" class="social"> <span class="icon-facebook"></span> </a> <a href="https://twitter.com/" class="social"> <span class="icon-twitter"></span> </a> <a href="https://www.pinterest.com/" class="social"> <span class="icon-pinterest"></span> </a> </div> </div> <div class="container container--full row center-xs middle-xs f-copyright"> CFAH is not a medical provider or treatment provider and does not provide medical advice. 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