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Healthcare, a division of General Electric Company (NYSE: GE), marking further progress toward establishing the first existing commercially viable domestic source of the radioisotope 99molybdenum (99Mo). 99Mo is the parent isotope of 99mtechnetium (99mTc), the most widely […]" /> <meta property="og:url" content="https://www.northstarnm.com/northstar-medical-radioisotopes-signs-letter-intent-ge-healthcare-2/" /> <meta property="og:site_name" content="NorthStar Medical Radioisotopes, LLC" /> <meta property="article:published_time" content="2014-08-14T16:17:14+00:00" /> <meta property="og:image" content="https://www.northstarnm.com/wp-content/uploads/2021/04/ns-logo.png" /> <meta property="og:image:width" content="1200" /> <meta property="og:image:height" content="630" /> <meta property="og:image:type" content="image/png" /> <meta name="author" content="Christine Pennekamp" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:creator" 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<p>Madison, Wis. – August 14, 2014 – NorthStar Medical Radioisotopes LLC has signed a non-exclusive letter of intent with GE Healthcare, a division of General Electric Company (NYSE: GE), marking further progress toward establishing the first existing commercially viable domestic source of the radioisotope <strong><sup>99</sup>molybdenum (<sup>99</sup>Mo)</strong>.</p> <p><sup>99</sup>Mo is the parent isotope of <strong><sup>99m</sup>technetium (<sup>99m</sup>Tc)</strong>, the most widely used radioisotope in medical diagnostic imaging. Under the purchase agreement, NorthStar will supply GE Healthcare with <sup>99</sup>Mo to produce <sup>99m</sup>Tc for compounding and distribution once its non-uranium-based <sup>99</sup>Mo production technology and proprietary RadioGenix isotope separation system have been approved by the U.S. Food and Drug Administration and are commercially available.</p> <p>NorthStar recently signed a similar agreement with the radiopharmacy chain Triad Isotopes, Inc.</p> <p>NorthStar, based in Madison, Wis., is developing a domestic source of <sup>99</sup>Mo to help alleviate chronic shortages. The <sup>99</sup>Mo will be produced without the use of weapons-useable highly enriched uranium (HEU), helping meet goals set by the U.S. Department of Energy’s (DOE) Global Threat Reduction Initiative (GTRI). The initiative was established to reduce and protect vulnerable nuclear and radiological material located at civilian sites worldwide and to minimize the use of HEU in civilian applications.</p> <p><sup>99m</sup>Tc is used in more than 13 million nuclear medicine procedures annually in the United States alone. Key applications include myocardial perfusion imaging (testing how well blood flows through the heart), sentinel node mapping (detecting whether breast cancer cells have spread to the sentinel lymph nodes), hepatobiliary imaging (evaluating the liver, gallbladder and ducts that are part of the biliary system), and inflammation and infection imaging.</p> <p>Currently, nearly all <sup>99</sup>Mo is produced using weapons-useable HEU at aging facilities located outside of the United States, leading to product shortages and creating safety and national security concerns. DOE, through GTRI, works with commercial entities to accelerate the establishment of domestic sources of <sup>99</sup>Mo produced without HEU.</p> <p>NorthStar has two methods of producing non-HEU <sup>99</sup>Mo, both of which generate only a benign waste stream. The non-HEU <sup>99</sup>Mo produced by NorthStar is for use in the company’s intelligent isotope separation system, the RadioGenix, the first true technological breakthrough in <sup>99</sup>Mo/<sup>99m</sup>Tc systems in nearly 45 years.</p> <p>NorthStar President and Chief Executive Officer George P. Messina said, “Together, NorthStar and GE Healthcare will help ensure that health care professionals have reliable access to the <sup>99m</sup>Tc isotope they need to give their patients accurate diagnoses and conduct important research. And because the <sup>99</sup>Mo parent radioisotope will be produced without the use of highly enriched uranium, we will be helping the United States achieve vital national security and safety goals.”</p> <p>GE Healthcare Global Product Leader Julie Woodland said, “Continuity of supply of <sup>99</sup>Mo to meet the growing demand for diagnostic procedures is a key focus for GE Healthcare. The company is actively working with new alternative <sup>99m</sup>Tc sources to help ensure that access to the radioisotope is readily available to aid in the diagnosis of patients both today and in the future.”</p> <p><strong>NorthStar Medical Radioisotopes LLC</strong><br /> Based in Madison, Wis., NorthStar Medical Radioisotopes LLC (<a href="https://www.northstarnm.com/news/ge-letter-of-intent">northstarnm.com</a>) was founded in 2006 to address the needs of the nuclear medicine market in the United States. A wholly owned subsidiary of NorthStar Medical Technologies LLC, the company is committed to resolving industry-wide supply challenges that have caused shortages of vital medical isotopes, negatively impacting patient care and stalling clinical research. Its patented technologies include innovative non-uranium based <sup>99</sup>molybdenum production methods, a novel separation chemistry system and tools for the nuclear medicine market.</p> <p><strong>GE Healthcare</strong><br /> GE Healthcare provides transformational medical technologies and services to meet the demand for increased access, enhanced quality and more affordable health care around the world. GE (NYSE: GE) works on things that matter – great people and technologies taking on tough challenges. From medical imaging, software and IT, patient monitoring and diagnostics to drug discovery, biopharmaceutical manufacturing technologies and performance improvement solutions, GE Healthcare helps medical professionals deliver great health care to their patients. 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