Genomic Instability and Cancer: Mechanisms and Therapeutic I

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Understanding the mechanisms underlying genomic instability is ..106428"/> <meta name="citation_publisher" content="希拉里斯有限公司" /> <meta name="citation_journal_title" content="遗传学和 DNA 研究杂志"> <meta name="citation_title" content="Genomic Instability and Cancer: Mechanisms and Therapeutic Implications"> <meta name="citation_author" content="Diego Fern" /> <meta name="citation_author" content="ez" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="8"> <meta name="citation_issue" content="2"> <meta name="citation_abstract" content="Genomic instability is a hallmark of cancer, driving tumorigenesis and tumor evolution. Understanding the mechanisms underlying genomic instability is crucial for developing effective cancer therapies. This mini-review explores the various causes of genomic instability, including DNA damage, replication errors and impaired DNA repair mechanisms. We discuss the implications of genomic instability for cancer development, progression and therapeutic resistance. 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</div> </div> </div> </div> <div class="col-lg-3 col-md-4"> <div class="card bg-amber-400 border-0"> <div class="card-body p-2 d-flex align-items-center"> 提交稿件 <a class="animate-icon mx-3 stretched-link" href="https://www.scholarscentral.org/submissions/genetics-dna-research.html" title="点击这里" target="_blank"> <span target="_blank" class="animate-icon-horizontal"> <i class="material-icons animate-icon-horizontal-wrap animate-icon-left-to-right">arrow_forward</i> <i class="material-icons animate-icon-horizontal-wrap animate-icon-left-to-right">arrow_forward</i> </span> </a> <img src="/assets/img/manuscript.svg" alt=".." width="50"> </div> </div> <div class="mt-2 cu_whatsapp"> </div> </div> </div> </header> <section class="container"> <div class="row"> <div class="col-sm"> <h2>Genomic Instability and Cancer: Mechanisms and Therapeutic Implications</h2> <h3>Abstract</h3> <p><i class="fas fa-user"></i> Diego Fernandez*</p> <p><p>Genomic instability is a hallmark of cancer, driving tumorigenesis and tumor evolution. Understanding the mechanisms underlying genomic instability is crucial for developing effective cancer therapies. This mini-review explores the various causes of genomic instability, including DNA damage, replication errors and impaired DNA repair mechanisms. We discuss the implications of genomic instability for cancer development, progression and therapeutic resistance. Furthermore, we highlight emerging therapeutic strategies targeting genomic instability pathways for cancer treatment.</p></p> <div class="alert alert-info text-left"><b>免责声明:</b> 此摘要通过人工智能工具翻译，尚未经过审核或验证</div> <div class="row mt-3"> <div class="col-12 col-sm-auto"> <p class="lead">分享此文章</p> </div> <div class="col-12 col-sm-auto"> <div class="nav social-icons"> <a title="点击这里" target="_blank" href="https://www.facebook.com/sharer.php?u=https://chinese.hilarispublisher.com/abstract/genomic-instability-and-cancer-mechanisms-and-therapeutic-implications-106428.html" class="nav-link bg-facebook fab fa-facebook-f text-white"> </a> <a title="点击这里" target="_blank" href="https://twitter.com/share?url=https://chinese.hilarispublisher.com/abstract/genomic-instability-and-cancer-mechanisms-and-therapeutic-implications-106428.html" class="nav-link bg-twitter fab fa-twitter text-white"> </a> <a title="点击这里" target="_blank" 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