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Innovations in Parkinson’s Disease Research and Treatment – Neurology
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category-parkinsons-disease tag-deep-brain-stimulation tag-early-diagnosis tag-gene-therapy tag-immunotherapy tag-neuroprotective-agents tag-non-motor-symptoms tag-parkinsons-disease tag-prodromal-parkinsons-disease" itemtype="https://schema.org/CreativeWork" itemscope> <div class="inside-article"> <div class="featured-image page-header-image-single "> <img width="1200" height="628" src="https://neurocare.blog/archive/wp-content/uploads/2024/09/image-_24_-min-scaled-e1725969736411.jpg" class="attachment-full size-full" alt="" itemprop="image" decoding="async" fetchpriority="high" /> </div> <header class="entry-header"> <h1 class="entry-title" itemprop="headline">Innovations in Parkinson’s Disease Research and Treatment</h1> <div class="entry-meta"> <span class="posted-on"><time class="entry-date published" datetime="2024-09-10T17:32:22+05:30" itemprop="datePublished">September 10, 2024</time></span> <span class="byline">by <span class="author vcard" itemprop="author" itemtype="https://schema.org/Person" itemscope><a class="url fn n" href="https://neurocare.blog/archive/author/neurocare/" title="View all posts by neurocare" rel="author" itemprop="url"><span class="author-name" itemprop="name">neurocare</span></a></span></span> </div> </header> <div class="entry-content" itemprop="text"> <p><span style="font-weight: 400;">Parkinson’s disease (PD) is a revolutionary neurodegenerative sickness characterized by means of the slow lack of dopaminergic neurons in the substantia nigra, mainly motor signs and symptoms including tremors, tension, bradykinesia, and postural instability.</span><span style="font-weight: 400;"> With over 10 million people affected around ground, Parkinson’s disease is one of the toughest diseases in medicine to deal with. Moreover, trending developments in research and cure are paving new thoughts. This article explores trending innovations in the field that are expertized in diagnostic techniques, cure solutions and upcoming treatment solutions.</span><span style="font-weight: 400;"><br /> </span></p> <h3><b>Diagnostic Innovations</b></h3> <p><b>Early Detection and Prodromal PD</b><b><br /> </b><span style="font-weight: 400;">The task involved in Parkinson’s Disease treatment is early diagnosis. Traditional methods usually depend upon the advent of motor signs, which means the ailment is already advanced by the point of diagnosis.</span><span style="font-weight: 400;"> The development of research standards for prodromal PD, as described in current research, represents a massive leap forward. These standards intend to perceive early symptoms and signs and symptoms of PD neurodegeneration earlier than traditional motor signs and symptoms emerge.</span><span style="font-weight: 400;"> Using a Bayesian naive classifier, those criteria integrate environmental chance elements, genetic findings, and diagnostic markers trying out to estimate an individual’s risk of prodromal PD with excessive actuality. This early detection is essential for implementing neuroprotective strategies that might sluggish the ailment’s progression.</span><span style="font-weight: 400;"><br /> <b></b></span></p> <p><span style="font-weight: 400;"><b>Midbrain ultrasound and olfactory checking out</b><br /> </span></p> <p><span style="font-weight: 400;">Another modern approach to early analysis of PD is the combined use of midbrain ultrasound, olfactory checking out, and motor function assessment. Studies have shown that capabilities along with substantia nigra hyperechoic, hyposmia, and irregular motor signs can appreciably improve diagnostic specificity.</span><span style="font-weight: 400;"> When these functions are assessed collectively, they provide a very sensitive and unique method to distinguishing PD from different Parkinson disorders, even inside the early tiers of the disease.</span><span style="font-weight: 400;"><br /> </span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Yearwise Publication Trend on <b>“<a href="https://neurocare.blog/publication-trends/index/parkinsons disease" target="_blank" title="parkinsons disease - yearwise publication trends">parkinsons disease</a>”</b></h2> </div> </div><div class="results-container"><div class="chart-block" style="padding:15px;"> <div class="left"> <div id="results" class="results"></div> </div> <div class="right"> <div class="chart-container"><canvas id="publicationChart"></canvas></div> </div> <div class="keywordsdiv"> <div style="text-align:center;"><b>Find publication trends on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-stats"></span> </div> </div></div></div><div class="inside-article"><style> table { margin: 0 0 1.5em; 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The surgical operation entails im</span><span style="font-weight: 400;">planting electrodes in precise regions of the min, that can then be linked to a pacemaker-like device that sends electric pulses to adjust ordinary mind activity. DBS has been shown to be particularly powerful in decreasing motor symptoms and improving fineness of life in Parkinson’s sufferers who no longer respond properly to medication. Advances in DBS technology, in addition to the development of adaptive DBS structures which can alter stimulation in real time based totally on brain activity, are enhancing the effectiveness and safety of this remedy.</span></p> <p><b>Gene Therapy</b></p> <p><b></b><span style="font-weight: 400;">Gene therapy is becoming the most prompt remedy for Parkinson’s disease</span><span style="font-weight: 400;"> This method involves turning genes immediately into the brain to supply proteins which could guard or regenerate dopaminergic neurons. Recent scientific trials have proven high quality results with gene therapy strategies aimed toward increasing the manufacturing of dopamine or improving the mind’s natural defensive mechanisms.</span></p> <p><b>Neuroprotective Agents</b></p> <p><span style="font-weight: 400;">Innovation into neuroprotective agents which can halt the growth of Parkinson’s disease is gaining momentum.</span><span style="font-weight: 400;"> Compounds that concentrate on oxidative strain,infection, and mitochondrial dysfunction are being explored for his or her capacity to protect neurons from degeneration. For instance, the repurposing of existing tablets with known safety profiles, inclusive of certain diabetes medicinal drugs, is displaying promise in early trials.</span><span style="font-weight: 400;"> </span></p> <p><b>Immunotherapy</b></p> <p><span style="font-weight: 400;">Immunotherapy , which has impacted most cancer cures, is now being researched for Parkinson’s cure. This process involves the usage of antibodies to target and clean pathological proteins, involving alpha – synuclein, which might be applied in the neurodegenerative manner . Starting research has proved that immunotherapy can decrease the accumulation of these proteins within the brain and is capable of gradual ailment progression. As this stream evolves, it could provide a good treatment to address the underlying reason of PD.</span></p> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Recent Publications on <b>“<a href="https://neurocare.blog/recent-publications/index/parkinsons disease" target="_blank" rel="noopener" title="parkinsons disease - yearwise publication list">parkinsons disease</a>”</b></h2> </div> </div> <div class="pb-main"><div class="article-scroll"><div id="results_recent" class="results"></div></div><div class="keywordsdiv" style="margin: 0px 15px;margin-top:20px;"> <div style="text-align:center;"><b>Find publications on relevant topics</b> </div> <span class="gp-icon icon-tags"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M20 39.5c-8.836 0-16 7.163-16 16v176c0 4.243 1.686 8.313 4.687 11.314l224 224c6.248 6.248 16.378 6.248 22.626 0l176-176c6.244-6.244 6.25-16.364.013-22.615l-223.5-224A15.999 15.999 0 00196.5 39.5H20zm56 96c0-13.255 10.745-24 24-24s24 10.745 24 24-10.745 24-24 24-24-10.745-24-24z"></path><path d="M259.515 43.015c4.686-4.687 12.284-4.687 16.97 0l228 228c4.686 4.686 4.686 12.284 0 16.97l-180 180c-4.686 4.687-12.284 4.687-16.97 0-4.686-4.686-4.686-12.284 0-16.97L479.029 279.5 259.515 59.985c-4.686-4.686-4.686-12.284 0-16.97z"></path></svg></span> <span id="keyword-papers"></span> </div></div></div><div class="inside-article"> <style> .pb-main{ border: solid 1px #ccc; border-top: none; margin-bottom: 20px; padding-bottom: 25px; background:#fff; } .author-main { border: solid 1px #ccc; border-top: none; margin-bottom: 20px; padding-bottom: 25px; background:#fff; } .publication-block { padding: 10px; margin-bottom: 10px; background-color: #f9f9f9; text-align: left; background: #FFF; border-bottom: solid 1px #ccc; margin-left: 15px; margin-right: 15px; } .publication-block h3 { margin: 0 0 10px; color: #000!important; } .publication-block a { font-size: 16px !important; line-height: 1em; font-weight: 600; text-transform: none; color: #000; padding: 0px; } .publication-block a:hover{ color: #227cdc; text-decoration:underline; } .article-scroll { max-height: 445px; overflow-y: auto; overflow-x: hidden; } ::-webkit-scrollbar-track { -webkit-box-shadow: inset 0 0 6px rgba(0,0,0,0.3); background-color: #efefef; border-radius:30px; } ::-webkit-scrollbar { width: 6px; background-color: #efefef; border-radius:30px; } ::-webkit-scrollbar-thumb { background-color: #ababab; border-radius:30px; } .publication-block p { margin-bottom: .5em; font-size: 15px; color: #000; } h3 { font-size: 18px !important; margin-bottom: 20px; line-height: 1.2em; font-weight: 600; text-transform: none; } a { padding: 5px; color: #a71c49; } #keyword-papers{ margin-top: 20px; text-align: center; } </style> <script> function decodeString(str) { str = str.replace(/\\'/g, "'"); str = str.replace(/\\'/g, "'"); str = str.replace(/\\'/g, "'"); return str; } function displayResults_recent(papers) { var resultsContainer = document.getElementById('results_recent'); if (!papers || papers.length === 0) { resultsContainer.innerHTML = '<p>No recent publications found.</p>'; return; } papers.forEach(paper => { var publicationBlock = document.createElement('div'); publicationBlock.className = 'publication-block'; var title_de = decodeString(paper.title); var publicationHTML = ` <div style="margin-bottom: 10px;line-height: 24px;"><a href="${paper.url}" target="_blank" title="${title_de}">${title_de}</a></div> <p><strong>Issue Release:</strong> ${paper.publishedDate}</p> `; publicationBlock.innerHTML = publicationHTML; resultsContainer.appendChild(publicationBlock); }); } function displayKeywordPapers(keywords) { var resultsContainer = document.getElementById('keyword-papers'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach((key, index) => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://neurocare.blog/recent-publications/index/${key_replace}" target="_blank" title="${key} - publication list">${key}</a>`; if (index < keywords.length - 1) { keywordHTML += ', '; } }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var recent_papers = [ { "title": "Exploring the complex interplay between Parkinson\\\\\\'s Disease and BAG proteins.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38768687", "publishedDate": "2024" }, { "title": "Identification and validation of N-acetylputrescine in combination with non-canonical clinical features as a Parkinson\\\\\\'s disease biomarker panel.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38693432", "publishedDate": "2024" }, { "title": "Therapeutic Implications and Regulations of Protein Post-translational Modifications in Parkinsons Disease.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38960968", "publishedDate": "2024" }, { "title": "Empowering the management of early-onset Parkinsons\\\\\\' disease: The role of technology.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38991885", "publishedDate": "2024" }, { "title": "Screening of key immunerelated gene in Parkinsons disease based on WGCNA and machine learning.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38755717", "publishedDate": "2024" }, { "title": "Awake versus Asleep Anesthesia in Deep Brain Stimulation Surgery for Parkinson\\\\\\'s Disease: A Systematic Review and Meta-Analysis.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/38636468", "publishedDate": "2024" }, { "title": "The outcomes of constrained total hip arthroplasty for recurrent dislocation of hip hemiarthroplasty.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37595486", "publishedDate": "2023" }, { "title": "Anthropology of Deep Brain Stimulation; the 30th Anniversary of STN DBS in 2023.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37772285", "publishedDate": "2023" }, { "title": "Capturing the Abnormal Brain Network Activity in Early Parkinsons Disease with Mild Cognitive Impairment based on Dynamic Functional Connectivity.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37022414", "publishedDate": "2023" }, { "title": "Cannabinoids in neuroinflammatory disorders: Focusing on multiple sclerosis, Parkinsons, and Alzheimers diseases.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/36637897", "publishedDate": "2023" }, { "title": "Andrographis paniculata and Andrographolide - A snapshot on Recent Advances in Nano Drug Delivery Systems Against Cancer.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/36740794", "publishedDate": "2023" }, { "title": "Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson\\\\\\'s disease.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37024536", "publishedDate": "2023" }, { "title": "Design of the STEPS trial: a phase II randomized controlled trial evaluating eHealth-supported\u00a0motor-cognitive home training for Parkinson\\\\\\'s disease.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37794320", "publishedDate": "2023" }, { "title": "The biology, pathological roles of exosomes and their clinical application in Parkinsons disease.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37689233", "publishedDate": "2023" }, { "title": "Deep brain stimulation, lesioning, focused ultrasound: update on utility.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37426775", "publishedDate": "2023" }, { "title": "Granulins rescue inflammation, lysosome dysfunction, and neuropathology in a mouse model of progranulin deficiency.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/37131734", "publishedDate": "2023" }, { "title": "Is intermittent control the source of the non-linear oscillatory component (0.2-2Hz) in human balance control.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/35560085", "publishedDate": "2022" }, { "title": "MNC-Net: Multi-task graph structure learning based on node clustering for early Parkinson\\\\\\'s disease diagnosis.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/36462371", "publishedDate": "2022" }, { "title": "Prevalence and Risk Factors of Peripheral Neuropathy in Parkinson\\\\\\'s Disease.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/36911466", "publishedDate": "2022" }, { "title": "Validation of a spatiotemporal gait model using inertial measurement units for early-stage Parkinson\\\\\\'s disease detection during turns.", "url": "https:\/\/pubmed.ncbi.nlm.nih.gov\/35511847", "publishedDate": "2022" } ]; var keywordsArray = ["Parkinson’s disease","Deep Brain Stimulation","Gene therapy","Neuroprotective agents","Immunotherapy","Early diagnosis","Prodromal Parkinson’s disease","Non-motor symptoms"]; displayResults_recent(recent_papers); displayKeywordPapers(keywordsArray); // function stripslashes(str) { // if (typeof str === 'string') { // return str.replace(/\/g, ''); // } // } </script></p> <h3><b>Evolving Understanding of Parkinson’s Disease</b></h3> <p><b>Redefining Parkinson’s Disease:</b></p> <p><span style="font-weight: 400;">To know how Parkinson’s disease is regularly seeing advancements , edging to effort to redefine the disease. The popularity that PD contains a high extensive spectrum of motor and non- motor signs , as well as a great difference in disease progression, has brought about the results of new diagnostic criteria. These criteria aim to click the heterogeneity of PD and recognize various subtypes that can rely on treatment. This clear understanding is crucial for customized medication processes that tailor cure to patients.</span><span style="font-weight: 400;"><br /> </span><span style="font-weight: 400;"><br /> </span><b>The Role of Non-Motor Symptoms:</b></p> <p><span style="font-weight: 400;">Non- motor symptoms of Parkinson’s ailment,involving cognitive impairment, temper issues, and autonomic disorder, are gaining higher attention. These signs and symptoms can highly affect the exceptional of existence and continuously precede motor signs. Addressing non- motor signs through collective care techniques is turning into an important part of PD.</span></p> <h3><b>Conclusion</b></h3> <p><span style="font-weight: 400;">The stream of Parkinson’s disease research and cure is having great evolution having quick healing and early diagnostics, good healing techniques and a pioneering specialization of the difficulty. These developments give strategy for further management and good cure techniques that might be miraculous in Parkinson’s disease cure. Main challenges are these developments and enhanced research’s utilization in medical exercise, finally improving the lives of those suffering from Parkinson’s disease.</span></p> <p></p> <h3><b>References</b></h3> <ol> <li> <div class="citation-text">Berg D, Postuma RB, Adler CH, Bloem BR, Chan P, Dubois B, Gasser T, Goetz CG, Halliday G, Joseph L, Lang AE, Liepelt-Scarfone I, Litvan I, Marek K, Obeso J, Oertel W, Olanow CW, Poewe W, Stern M, Deuschl G. <a href="https://pubmed.ncbi.nlm.nih.gov/26474317/">MDS research criteria for prodromal Parkinson’s disease.</a> Mov Disord. 2015 Oct;30(12):1600-11. doi: 10.1002/mds.26431. PMID: 26474317.</div> </li> <li> <div class="citation-text">Adler CH, Beach TG, Hentz JG, Shill HA, Caviness JN, Driver-Dunckley E, Sabbagh MN, Sue LI, Jacobson SA, Belden CM, Dugger BN. <a href="https://pubmed.ncbi.nlm.nih.gov/24975862/">Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study. Neurology.</a> 2014 Jul 29;83(5):406-12. doi: 10.1212/WNL.0000000000000641. Epub 2014 Jun 27. PMID: 24975862; PMCID: PMC4132570.</div> </li> <li> <div class="citation-text">Berg D, Postuma RB, Bloem B, Chan P, Dubois B, Gasser T, Goetz CG, Halliday GM, Hardy J, Lang AE, Litvan I, Marek K, Obeso J, Oertel W, Olanow CW, Poewe W, Stern M, Deuschl G. <a href="https://pubmed.ncbi.nlm.nih.gov/24619848/">Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson’s disease.</a> Mov Disord. 2014 Apr;29(4):454-62. doi: 10.1002/mds.25844. Epub 2014 Mar 11. PMID: 24619848; PMCID: PMC4204150.</div> </li> <li> <div class="citation-text">Busse K, Heilmann R, Kleinschmidt S, Abu-Mugheisib M, Höppner J, Wunderlich C, Gemende I, Kaulitz L, Wolters A, Benecke R, Walter U. <a href="https://pubmed.ncbi.nlm.nih.gov/22362921/">Value of combined midbrain sonography, olfactory and motor function assessment in the differential diagnosis of early Parkinson’s disease.</a> J Neurol Neurosurg Psychiatry. 2012 Apr;83(4):441-7. doi: 10.1136/jnnp-2011-301719. Epub 2012 Feb 22. PMID: 22362921.</div> </li> <li> <div class="citation-text">Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170532/">Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.</a> Brain. 2011 Sep;134(Pt 9):2456-77. doi: 10.1093/brain/awr179. Epub 2011 Aug 2. PMID: 21810890; PMCID: PMC3170532.</div> </li> <li>Goetz, C.G., Tilley, B.C., Shaftman, S.R., Stebbins, G.T., Fahn, S., Martinez‐Martin, P., Poewe, W., Sampaio, C., Stern, M.B., Dodel, R. and Dubois, B., 2008. <a href="https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.22340">Movement Disorder Society‐sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS‐UPDRS): scale presentation and clinimetric testing results.</a> <i>Movement disorders: official journal of the Movement Disorder Society</i>, <i>23</i>(15), pp.2129-2170.</li> </ol> <p></div></div> <div style="background: #f7f7f7;border: 1px solid rgba(0, 0, 0, 0.07);"> <div style="padding: 30px;"><div class="Adblock-main"> <div class="Adblock-head"> <h2>Top Experts on “<b style="color:#000;font-size:22px;">parkinsons disease</b>“</h2> </div> </div><div class="author-main"><div id="results_author"></div><div style="text-align: center;"><a class="register-button" href="https://neurocare.blog/expert-search" target="_blank" rel="noopener">Find experts on any field</a></div></div><div class="inside-article" style="background: none;border: none;box-shadow: none;margin-top: -70px;"> <style> .author-block { padding: 15px; margin-bottom: 10px; text-align: left; font-size: 15px; line-height: 1.2; background: #FFF; border-bottom: solid 1px #ccc; margin-left: 15px; margin-right: 15px; } .author-block h3 { margin: 0 0 10px; color: #227cdc; } .author-block p { margin: 5px 0; } .author-b { display: flex; justify-content: space-between; flex-wrap: wrap; margin-bottom:10px; } .author-b .ainfo { flex: 1 1 30%; box-sizing: border-box; text-align: left; background: #dcdcdc; padding: 7px 14px; border-radius: 5px; margin-top: 3px; margin-right: 10px; } @media (max-width: 768px) { .author-b .ainfo { flex: 1 1 100%; margin: 10px 0; } } </style> <script> function displayResults_author(authors) { var resultsContainer = document.getElementById('results_author'); resultsContainer.innerHTML = ''; if (!authors || Object.keys(authors).length === 0) { resultsContainer.innerHTML = '<p>No authors found.</p>'; return; } Object.values(authors).slice(0, 10).forEach(author => { if (author.affiliation.length > 400) { return; } var authorBlock = document.createElement('div'); authorBlock.className = 'author-block'; var author_name=author.name; let key_replace = author_name.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); var authorHTML = ` <h3><a href="https://neurocare.blog/author/index/${key_replace}\/${author.aid}" target="_blank" title="${author.name}">${author.name}</a></h3> <div class="author-b"> <div class="ainfo"><strong>H-Index:</strong> ${author.hindex}</div> <div class="ainfo"><strong>Publication Count:</strong> ${author.paper_count}</div> <div class="ainfo"><strong>Citation Count:</strong> ${author.citation_count}</div> </div> <p><strong>Affiliation:</strong> ${author.affiliation}</p> `; authorBlock.innerHTML = authorHTML; resultsContainer.appendChild(authorBlock); }); } function displayKeywordAuthors(keywords) { var resultsContainer = document.getElementById('keyword-authors'); resultsContainer.innerHTML = ''; if (!keywords || keywords.length === 0) { resultsContainer.innerHTML = '<p>No data found.</p>'; return; } var keywordHTML = ''; keywords.forEach(key => { let key_replace = key.replace(/ /g, '-'); key_replace = key_replace.toLowerCase(); keywordHTML += `<a href="https://neurocare.blog/expert-search/index/${key_replace}" target="_blank" title="${key}">${key}</a>`; }); resultsContainer.innerHTML = keywordHTML; } // Call the function with the PHP data var authors_data = { "vRBtK4wBWBy50K-rvd9v": { "aid": "vRBtK4wBWBy50K-rvd9v", "name": "N. 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", "email": "shaheen.jafri@gmail.com", "slug_tail": "shaheen-ali" } }; //console.log(authors_data); displayResults_author(authors_data); var keywordsArray = ["Parkinson’s disease","Deep Brain Stimulation","Gene therapy","Neuroprotective agents","Immunotherapy","Early diagnosis","Prodromal Parkinson’s disease","Non-motor symptoms"]; displayKeywordAuthors(keywordsArray); </script></p> </div> <footer class="entry-meta" aria-label="Entry meta"> <span class="cat-links"><span class="gp-icon icon-categories"><svg viewBox="0 0 512 512" aria-hidden="true" xmlns="http://www.w3.org/2000/svg" width="1em" height="1em"><path d="M0 112c0-26.51 21.49-48 48-48h110.014a48 48 0 0143.592 27.907l12.349 26.791A16 16 0 00228.486 128H464c26.51 0 48 21.49 48 48v224c0 26.51-21.49 48-48 48H48c-26.51 0-48-21.49-48-48V112z" /></svg></span><span class="screen-reader-text">Categories </span><a href="https://neurocare.blog/archive/category/parkinsons-disease/" rel="category tag">Parkinson's Disease</a></span> <span 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