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Gamal</title> <meta name="description" content="Search results for: Mostafa Gamal"> <meta name="keywords" content="Mostafa Gamal"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Mostafa Gamal"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 253</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Mostafa Gamal</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">43</span> BiFormerDTA: Structural Embedding of Protein in Drug Target Affinity Prediction Using BiFormer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leila%20Baghaarabani">Leila Baghaarabani</a>, <a href="https://publications.waset.org/abstracts/search?q=Parvin%20Razzaghi"> Parvin Razzaghi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mennatolla%20Magdy%20Mostafa"> Mennatolla Magdy Mostafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Albaqsami"> Ahmad Albaqsami</a>, <a href="https://publications.waset.org/abstracts/search?q=Al%20Warith%20Al%20Rushaidi"> Al Warith Al Rushaidi</a>, <a href="https://publications.waset.org/abstracts/search?q=Masoud%20Al%20Rawahi"> Masoud Al Rawahi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Predicting the interaction between drugs and their molecular targets is pivotal for advancing drug development processes. Due to the time and cost limitations, computational approaches have emerged as an effective approach to drug-target interaction (DTI) prediction. Most of the introduced computational based approaches utilize the drug molecule and protein sequence as input. This study does not only utilize these inputs, it also introduces a protein representation developed using a masked protein language model. In this representation, for every individual amino acid residue within the protein sequence, there exists a corresponding probability distribution that indicates the likelihood of each amino acid being present at that particular position. Then, the similarity between each pair of amino acids is computed to create a similarity matrix. To encode the knowledge of the similarity matrix, Bi-Level Routing Attention (BiFormer) is utilized, which combines aspects of transformer-based models with protein sequence analysis and represents a significant advancement in the field of drug-protein interaction prediction. BiFormer has the ability to pinpoint the most effective regions of the protein sequence that are responsible for facilitating interactions between the protein and drugs, thereby enhancing the understanding of these critical interactions. Thus, it appears promising in its ability to capture the local structural relationship of the proteins by enhancing the understanding of how it contributes to drugprotein interactions, thereby facilitating more accurate predictions. To evaluate the proposed method, it was tested on two widely recognized datasets: Davis and KIBA. A comprehensive series of experiments was conducted to illustrate its effectiveness in comparison to cutting edge techniques. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=BiFormer" title="BiFormer">BiFormer</a>, <a href="https://publications.waset.org/abstracts/search?q=transformer" title=" transformer"> transformer</a>, <a href="https://publications.waset.org/abstracts/search?q=protein%20language%20processing" title=" protein language processing"> protein language processing</a>, <a href="https://publications.waset.org/abstracts/search?q=self-attention%20mechanism" title=" self-attention mechanism"> self-attention mechanism</a>, <a href="https://publications.waset.org/abstracts/search?q=binding%20affinity" title=" binding affinity"> binding affinity</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20target%20interaction" title=" drug target interaction"> drug target interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=similarity%20matrix" title=" similarity matrix"> similarity matrix</a>, <a href="https://publications.waset.org/abstracts/search?q=protein%20masked%20representation" title=" protein masked representation"> protein masked representation</a>, <a href="https://publications.waset.org/abstracts/search?q=protein%20language%20model" title=" protein language model"> protein language model</a> </p> <a href="https://publications.waset.org/abstracts/194594/biformerdta-structural-embedding-of-protein-in-drug-target-affinity-prediction-using-biformer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194594.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">7</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">42</span> Effect of Different Porous Media Models on Drug Delivery to Solid Tumors: Mathematical Approach</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Sefidgar">Mostafa Sefidgar</a>, <a href="https://publications.waset.org/abstracts/search?q=Sohrab%20Zendehboudi"> Sohrab Zendehboudi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hossein%20Bazmara"> Hossein Bazmara</a>, <a href="https://publications.waset.org/abstracts/search?q=Madjid%20Soltani"> Madjid Soltani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Based on findings from clinical applications, most drug treatments fail to eliminate malignant tumors completely even though drug delivery through systemic administration may inhibit their growth. Therefore, better understanding of tumor formation is crucial in developing more effective therapeutics. For this purpose, nowadays, solid tumor modeling and simulation results are used to predict how therapeutic drugs are transported to tumor cells by blood flow through capillaries and tissues. A solid tumor is investigated as a porous media for fluid flow simulation. Most of the studies use Darcy model for porous media. In Darcy model, the fluid friction is neglected and a few simplified assumptions are implemented. In this study, the effect of these assumptions is studied by considering Brinkman model. A multi scale mathematical method which calculates fluid flow to a solid tumor is used in this study to investigate how neglecting fluid friction affects the solid tumor simulation. In this work, the mathematical model in our previous studies is developed by considering two model of momentum equation for porous media: Darcy and Brinkman. The mathematical method involves processes such as fluid flow through solid tumor as porous media, extravasation of blood flow from vessels, blood flow through vessels and solute diffusion, convective transport in extracellular matrix. The sprouting angiogenesis model is used for generating capillary network and then fluid flow governing equations are implemented to calculate blood flow through the tumor-induced capillary network. Finally, the two models of porous media are used for modeling fluid flow in normal and tumor tissues in three different shapes of tumors. Simulations of interstitial fluid transport in a solid tumor demonstrate that the simplifications used in Darcy model affect the interstitial velocity and Brinkman model predicts a lower value for interstitial velocity than the values that Darcy model does. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=solid%20tumor" title="solid tumor">solid tumor</a>, <a href="https://publications.waset.org/abstracts/search?q=porous%20media" title=" porous media"> porous media</a>, <a href="https://publications.waset.org/abstracts/search?q=Darcy%20model" title=" Darcy model"> Darcy model</a>, <a href="https://publications.waset.org/abstracts/search?q=Brinkman%20model" title=" Brinkman model"> Brinkman model</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery" title=" drug delivery"> drug delivery</a> </p> <a href="https://publications.waset.org/abstracts/37398/effect-of-different-porous-media-models-on-drug-delivery-to-solid-tumors-mathematical-approach" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37398.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">306</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">41</span> Support for Privilege Based on Nationality in Switched-At-Birth Scenario</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anne%20Lehner">Anne Lehner</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Salari%20Rad"> Mostafa Salari Rad</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Ginges"> Jeremy Ginges</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Many of life’s privileges (and burdens) are thrust on us at birth. Someone born white or male in the United States is also born with a set of advantages over someone born non-white or female. One aspect of privileges conferred by birth is that they are so entrenched in social institutions and social norms that until they are robustly challenged, they can be seen as a moral good. While American society increasingly confronts privileges based on gender and race, other types of privileges, like one's nationality, see less attention. The nationality one is born into can have enormous effects on one’s personal life, work opportunities, and health outcomes. Yet, we predicted that although most Americans would regard it as absurd to think that white people have a right to protect their privileges and 'way of life', they would regard it as obvious that Americans have a right to protect the American way of life and associated privileges. In a preregistered study we presented 300 Americans randomly with one out of three 'privilege scales' in order to assess their agreement with certain statements. The domains for the privilege scales were nationality, race, and gender. Next, all participants completed the switched-at-birth task assessing ones tendency to essentialize nationality. We found that Americans are more approving of privilege based on nationality than of privilege based on gender and race. In addition, we found an interaction of condition with ideology, showing that conservatives are in general more approving of the privilege of any kind than liberals are, and they especially approve of privilege based on nationality. For the switched-at-birth task, we found that both, liberals as well as conservatives are equally willing to grant the child 100% American nationality. Whether or not one chose 100% is unrelated to the expressed approval of privilege based on nationality. One might hesitate to fully grant the child 100% American nationality in the task, yet disapprove of privilege based on nationality. This shows that as much as we see beholders of privilege being oblivious to their statuses within other social categories, like gender or race, we seem to detect the same blindness for the privilege based on nationality. Liberals showing relatively fewer support for privilege based on nationality compared to conservatives still refused to acknowledge the child as having become 100% American and thereby denying the privileges it potentially bestows upon them. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=thought%20experiment" title="thought experiment">thought experiment</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-immigrant%20attitudes" title=" anti-immigrant attitudes"> anti-immigrant attitudes</a>, <a href="https://publications.waset.org/abstracts/search?q=privilege%20of%20nationality" title=" privilege of nationality"> privilege of nationality</a>, <a href="https://publications.waset.org/abstracts/search?q=immigration" title=" immigration"> immigration</a>, <a href="https://publications.waset.org/abstracts/search?q=moral%20circles" title=" moral circles"> moral circles</a>, <a href="https://publications.waset.org/abstracts/search?q=psychology" title=" psychology"> psychology</a> </p> <a href="https://publications.waset.org/abstracts/108796/support-for-privilege-based-on-nationality-in-switched-at-birth-scenario" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/108796.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">132</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">40</span> Antimicrobial Efficacy of Some Antibiotics Combinations Tested against Some Molecular Characterized Multiresistant Staphylococcus Clinical Isolates, in Egypt</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nourhan%20Hussein%20Fanaki">Nourhan Hussein Fanaki</a>, <a href="https://publications.waset.org/abstracts/search?q=Hoda%20Mohamed%20Gamal%20El-Din%20Omar"> Hoda Mohamed Gamal El-Din Omar</a>, <a href="https://publications.waset.org/abstracts/search?q=Nihal%20Kadry%20Moussa"> Nihal Kadry Moussa</a>, <a href="https://publications.waset.org/abstracts/search?q=Eva%20Adel%20Edward%20Farid"> Eva Adel Edward Farid</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The resistance of staphylococci to various antibiotics has become a major concern for health care professionals. The efficacy of the combinations of selected glycopeptides (vancomycin and teicoplanin) with gentamicin or rifampicin, as well as that of gentamicin/rifampicin combination, was studied against selected pathogenic staphylococcus isolated from Egypt. The molecular distribution of genes conferring resistance to these four antibiotics was detected among tested clinical isolates. Antibiotic combinations were studied using the checkerboard technique and the time-kill assay (in both the stationary and log phases). Induction of resistance to glycopeptides in staphylococci was tried in the absence and presence of diclofenac sodium as inducer. Transmission electron microscopy was used to study the effect of glycopeptides on the ultrastructure of the cell wall of staphylococci. Attempts were made to cure gentamicin resistance plasmids and to study the transfer of these plasmids by conjugation. Trials for the transformation of the successfully isolated gentamicin resistance plasmid to competent cells were carried out. The detection of genes conferring resistance to the tested antibiotics was performed using the polymerase chain reaction. The studied antibiotic combinations proved their efficacy, especially when tested during the log phase. Induction of resistance to glycopeptides in staphylococci was more promising in presence of diclofenac sodium, compared to its absence. Transmission electron microscopy revealed the thickening of bacterial cell wall in staphylococcus clinical isolates due to the presence of tested glycopeptides. Curing of gentamicin resistance plasmids was only successful in 2 out of 9 tested isolates, with a curing rate of 1 percent for each. Both isolates, when used as donors in conjugation experiments, yielded promising conjugation frequencies ranging between 5.4 X 10-2 and 7.48 X 10-2 colony forming unit/donor cells. Plasmid isolation was only successful in one out of the two tested isolates. However, low transformation efficiency (59.7 transformants/microgram plasmid DNA) of such plasmids was obtained. Negative regulators of autolysis, such as arlR, lytR and lrgB, as well as cell-wall associated genes, such as pbp4 and/or pbp2, were detected in staphylococcus isolates with reduced susceptibility to the tested glycopeptides. Concerning rifampicin resistance genes, rpoBstaph was detected in 75 percent of the tested staphylococcus isolates. It could be concluded that in vitro studies emphasized the usefulness of the combination of vancomycin or teicoplanin with gentamicin or rifampicin, as well as that of gentamicin with rifampicin, against staphylococci showing varying resistance patterns. However, further in vivo studies are required to ensure the safety and efficacy of such combinations. Diclofenac sodium can act as an inducer of resistance to glycopeptides in staphylococci. Cell-wall thickness is a major contributor to such resistance among them. Gentamicin resistance in these strains could be chromosomally or plasmid mediated. Multiple mutations in the rpoB gene could mediate staphylococcus resistance to rifampicin. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glycopeptides" title="glycopeptides">glycopeptides</a>, <a href="https://publications.waset.org/abstracts/search?q=combinations" title=" combinations"> combinations</a>, <a href="https://publications.waset.org/abstracts/search?q=induction" title=" induction"> induction</a>, <a href="https://publications.waset.org/abstracts/search?q=diclofenac" title=" diclofenac"> diclofenac</a>, <a href="https://publications.waset.org/abstracts/search?q=transmission%20electron%20microscopy" title=" transmission electron microscopy"> transmission electron microscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=polymerase%20chain%20reaction" title=" polymerase chain reaction"> polymerase chain reaction</a> </p> <a href="https://publications.waset.org/abstracts/3949/antimicrobial-efficacy-of-some-antibiotics-combinations-tested-against-some-molecular-characterized-multiresistant-staphylococcus-clinical-isolates-in-egypt" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3949.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">39</span> Yellow Necklacepod and Shih-Balady: Possible Promising Sources Against Human Coronaviruses</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Howaida%20I.%20Abd-Alla">Howaida I. Abd-Alla</a>, <a href="https://publications.waset.org/abstracts/search?q=Omnia%20Kutkat"> Omnia Kutkat</a>, <a href="https://publications.waset.org/abstracts/search?q=Yassmin%20Moatasim"> Yassmin Moatasim</a>, <a href="https://publications.waset.org/abstracts/search?q=Magda%20T.%20Ibrahim"> Magda T. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Marwa%20A.%20Mostafa"> Marwa A. Mostafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20GabAllah"> Mohamed GabAllah</a>, <a href="https://publications.waset.org/abstracts/search?q=Mounir%20M.%20El-Safty"> Mounir M. El-Safty</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Artemisia judaica (known shih-balady), Azadirachta indica and Sophora tomentosa (known yellow necklace pod) are members of available medicinal plants well-known for their traditional medical use in Egypt which suggests that they probably harbor broad-spectrum antiviral, immunostimulatory and anti-inflammatory functions. Their ethyl acetate-dichloromethane (1:1, v/v) extracts were evaluated for the potential anti-Middle East respiratory syndrome-related coronavirus (anti-MERS-CoV) activity. Their cytotoxic activity was tested in Vero-E6 cells using 3-(4,-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method with minor modification. The plot of percentage cytotoxicity for each extract concentration has calculated the concentration which exhibited 50% cytotoxic concentration (TC50). A plaque reduction assay was employed using safe dose of extract to evaluate its effect on virus propagation. The highest inhibition percentage was recorded for the yellow necklace pod, followed by Shih-balady. The possible mode of action of virus inhibition was studied at three different levels viral replication, viral adsorption and virucidal activity. The necklace pod leaves have induced virucidal effects and direct effects on the replication of virus. Phytochemical investigation of the promising necklace pod led to the isolation and structure determination of nine compounds. The structure of each compound was determined by a variety of spectroscopic methods. Compounds 4-O-methyl sorbitol 1, 8-methoxy daidzin 6 and 6-methoxy apigenin-7-O-β-D-glucopyranoside 8 were isolated for the first time from the Sophora genus and the other six compounds were the first time that they were isolated from this species according to available works of literature. Generally, the highest anti-CoV 2 activity of S. tomentosa was associated with the crude ethanolic extract, indicating the possibility of synergy among the antiviral phytochemical constituents (1-9). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=coronavirus" title="coronavirus">coronavirus</a>, <a href="https://publications.waset.org/abstracts/search?q=MERS-CoV" title=" MERS-CoV"> MERS-CoV</a>, <a href="https://publications.waset.org/abstracts/search?q=mode%20of%20action" title=" mode of action"> mode of action</a>, <a href="https://publications.waset.org/abstracts/search?q=necklace%20pod" title=" necklace pod"> necklace pod</a>, <a href="https://publications.waset.org/abstracts/search?q=shih-balady" title=" shih-balady"> shih-balady</a> </p> <a href="https://publications.waset.org/abstracts/140747/yellow-necklacepod-and-shih-balady-possible-promising-sources-against-human-coronaviruses" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140747.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">209</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">38</span> The Studies of the Impact of Biomimicry and Sustainability on Urban Design </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nourhane%20Mohamed%20El%20Haridi">Nourhane Mohamed El Haridi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20El%20Arabi"> Mostafa El Arabi</a>, <a href="https://publications.waset.org/abstracts/search?q=Zeyad%20El%20Sayad"> Zeyad El Sayad </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biomimicry is defined, by Benyus the natural sciences writer, as imitating or taking inspiration from nature’s forms and processes to solve human problems. Biomimicry is the conscious emulation of life’s genius. As the design community realizes the tremendous impact human constructions have on the world, environmental designers look to new approaches like biomimicry to advance sustainable design. Building leading the declaration made by biomimicry scientists that a full imitation of nature engages form, ecosystem, and process; this paper uses a logic approach to interpret human and environmental wholeness. Designers would benefit from both integrating social theory with environmental thinking and from combining their substantive skills with techniques for getting sustainable biomimic urban design. Integrating biomimicryʹs “Life’s Principles” into a built environment process model will make biomimicry more accessible and thus more widely accepted throughout the industry, and the sustainability of all species will benefit. The Biomimicry Guild hypothesizes the incorporation of these principles, called Lifeʹs Principles, increase the likelihood of sustainability for a respective design, and make it more likely that the design will have a greater impact on sustainability for future generations of all species as mentioned by Benyus in her book. This thesis utilizes Life’s Principles as a foundation for a design process model intended for application on built environment projects at various scales. This paper takes a look at the importance of the integration of biomimicry in urban design to get more sustainable cities and better life, by analyzing the principles of both sustainability and biomimicry, and applying these ideas on futuristic or existing cities to make a biomimic sustainable city more healthier and more conductive to life, and get a better biomimic urban design. A group of experts, architects, biologists, scientists, economists and ecologists should work together to face all the financial and designing difficulties, to have better solutions and good innovative ideas for biomimic sustainable urban design, it is not the only solution, but it is one of the best studies for a better future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomimicry" title="biomimicry">biomimicry</a>, <a href="https://publications.waset.org/abstracts/search?q=built%20environment" title=" built environment"> built environment</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=urban%20design" title=" urban design"> urban design</a> </p> <a href="https://publications.waset.org/abstracts/25384/the-studies-of-the-impact-of-biomimicry-and-sustainability-on-urban-design" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25384.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">522</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">37</span> History of Pediatric Renal Pathology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Elbaba">Mostafa Elbaba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Because childhood renal diseases are grossly different compared to adult diseases, pediatric nephrology was founded as a specialty in 1965. Renal pathology specialty was introduced at the London Ciba Symposium in 1961. The history of renal pathology can be divided into two eras: one starting in the 1650s with the invention of the microscope, the second in the 1950s with the implementation of renal biopsy, and the presence of electron microscopy and immunofluorescence study. Prior to the 1950s, the study of diseased human kidneys was restricted to postmortem examination by gross pathology. In 1827, Richard Bright first described his triad of kidney disease, which was confirmed by morbid kidney changes at autopsy. In 1905 Friedrich Mueller coined the term “nephrosis” describing the inflammatory form of “degenerative” diseases, and later F. Munk added the term “lipoid nephrosis”. The most profound influence on renal diseases’ classification came from the publication of Volhard and Fahr in 1914. In 1899, Carl Max Wilhelm Wilms described Wilms' tumor of the kidneys in children. Chronic pyelonephritis was a popular renal diagnosis and the most common cause of uremia until the 1960s. Although kidney biopsy had been used early in the 1930s for renal tumors, the earliest reports of its use in the diagnosis of medical kidney disease were by Iversen and Brun in 1951, followed by Alwall in 1952, then by Pardo in 1953. The earliest intentional renal biopsies were done in 1944 by Nils Alwall, while the procedure was abandoned after the death of one of his 13 patients who biopsied. In 1950, Antonino Perez-Ara attempted renal biopsies, but his results were missed because of an unpopular journal publication. In the year 1951, Claus Brun and Poul Iverson developed the biopsy procedure using an aspiration technique. Popularizing renal biopsy practice is accredited to Robert Kark, who published his distinct work in 1954. He perfected the technique of renal biopsy in the prone position using the Vim-Silverman needle and used intravenous pyelography to improve the localization of the kidney. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=history" title="history">history</a>, <a href="https://publications.waset.org/abstracts/search?q=medicine" title=" medicine"> medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=nephrology" title=" nephrology"> nephrology</a>, <a href="https://publications.waset.org/abstracts/search?q=pediatrics" title=" pediatrics"> pediatrics</a>, <a href="https://publications.waset.org/abstracts/search?q=pathology" title=" pathology"> pathology</a> </p> <a href="https://publications.waset.org/abstracts/173746/history-of-pediatric-renal-pathology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173746.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">59</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">36</span> The State of Research on Medicinal Plants in Morocco</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alami%20Ilyass">Alami Ilyass</a>, <a href="https://publications.waset.org/abstracts/search?q=Loubna%20Kharchoufa"> Loubna Kharchoufa</a>, <a href="https://publications.waset.org/abstracts/search?q=Elachouri%20Mostafa"> Elachouri Mostafa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The two great realms of living diversity are cultural and biological. Today, both are being lost at an alarming rate. Of all the Earth’s biological diversity, plant kingdom is of high significance, and most essential to human welfare, in fact, medicinal plants are extensively exploited for countless purposes. Among these multiple uses, medicinal plants are the most important source of medicine for humankind healthcare and well being. In recent years there has been a great surge of public interest in the use of herbs and plants. Some scientists have viewed this phenomenon as a modern “herbal renaissance”. The importance of plants as medicines in developed and developing countries has recently been acknowledged by the United Nations (UN). However, to date fewer than 5% of the approximately 250,000 species of higher plants have been exhaustively studied for their potential pharmacological activity. A number of drugs from ethnobotanical leads have provided significant milestones in Western medicine. Despite this success, pharmacognosy research on Moroccan flora needs more studies aimed at the exploration of their therapeutic potential. A major weakness is the absence of strong funding agencies in the country, and a real national drug discovery program. Moreover, the lack of the coordination between different universities and research institutions leads, in most cases, to a waste of time, money and efforts of many researchers. In this work, we focus our attention on research into traditional indigenous medicinal plants in Morocco. Three parts constitute the head lines of this work: In the first one, we take up Moroccan biodiversity matter, the second part is devoted principally to the state of research into medicinal plants by Moroccan scholars and the last one is consecrated to the debate of factors which handicap the progress of research on phytomedicine in Morocco. The objectives of the present study are twofold: first, to highlight the state of the medicinal plants researches in Morocco. Second goal is to assess and correlate the levels of knowledge of the local flora to the research on medicinal plants to attempt to build capacity for research within Moroccan Scientific community at rate of developing country. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Morocco" title="Morocco">Morocco</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title=" medicinal plants"> medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=ethnobotanical" title=" ethnobotanical"> ethnobotanical</a>, <a href="https://publications.waset.org/abstracts/search?q=pharmacognosy" title=" pharmacognosy"> pharmacognosy</a>, <a href="https://publications.waset.org/abstracts/search?q=phytomedicine" title=" phytomedicine"> phytomedicine</a> </p> <a href="https://publications.waset.org/abstracts/45391/the-state-of-research-on-medicinal-plants-in-morocco" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45391.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">187</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">35</span> Study of Morning-Glory Spillway Structure in Hydraulic Characteristics by CFD Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Zandi">Mostafa Zandi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ramin%20Mansouri"> Ramin Mansouri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Spillways are one of the most important hydraulic structures of dams that provide the stability of the dam and downstream areas at the time of flood. Morning-Glory spillway is one of the common spillways for discharging the overflow water behind dams, these kinds of spillways are constructed in dams with small reservoirs. In this research, the hydraulic flow characteristics of a morning-glory spillways are investigated with CFD model. Two dimensional unsteady RANS equations were solved numerically using Finite Volume Method. The PISO scheme was applied for the velocity-pressure coupling. The mostly used two-equation turbulence models, k- and k-, were chosen to model Reynolds shear stress term. The power law scheme was used for discretization of momentum, k , and  equations. The VOF method (geometrically reconstruction algorithm) was adopted for interface simulation. The results show that the fine computational grid, the input speed condition for the flow input boundary, and the output pressure for the boundaries that are in contact with the air provide the best possible results. Also, the standard wall function is chosen for the effect of the wall function, and the turbulent model k -ε (Standard) has the most consistent results with experimental results. When the jet is getting closer to end of basin, the computational results increase with the numerical results of their differences. The lower profile of the water jet has less sensitivity to the hydraulic jet profile than the hydraulic jet profile. In the pressure test, it was also found that the results show that the numerical values of the pressure in the lower landing number differ greatly in experimental results. The characteristics of the complex flows over a Morning-Glory spillway were studied numerically using a RANS solver. Grid study showed that numerical results of a 57512-node grid had the best agreement with the experimental values. The desired downstream channel length was preferred to be 1.5 meter, and the standard k-ε turbulence model produced the best results in Morning-Glory spillway. The numerical free-surface profiles followed the theoretical equations very well. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=morning-glory%20spillway" title="morning-glory spillway">morning-glory spillway</a>, <a href="https://publications.waset.org/abstracts/search?q=CFD%20model" title=" CFD model"> CFD model</a>, <a href="https://publications.waset.org/abstracts/search?q=hydraulic%20characteristics" title=" hydraulic characteristics"> hydraulic characteristics</a>, <a href="https://publications.waset.org/abstracts/search?q=wall%20function" title=" wall function"> wall function</a> </p> <a href="https://publications.waset.org/abstracts/167217/study-of-morning-glory-spillway-structure-in-hydraulic-characteristics-by-cfd-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167217.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">77</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">34</span> Ligandless Extraction and Determination of Trace Amounts of Lead in Pomegranate, Zucchini and Lettuce Samples after Dispersive Liquid-Liquid Microextraction with Ultrasonic Bath and Optimization of Extraction Condition with RSM Design</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fariba%20Tadayon">Fariba Tadayon</a>, <a href="https://publications.waset.org/abstracts/search?q=Elmira%20Hassanlou"> Elmira Hassanlou</a>, <a href="https://publications.waset.org/abstracts/search?q=Hasan%20Bagheri"> Hasan Bagheri</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Jafarian"> Mostafa Jafarian</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Heavy metals are released into water, plants, soil, and food by natural and human activities. Lead has toxic roles in the human body and may cause serious problems even in low concentrations, since it may have several adverse effects on human. Therefore, determination of lead in different samples is an important procedure in the studies of environmental pollution. In this work, an ultrasonic assisted-ionic liquid based-liquid-liquid microextraction (UA-IL-DLLME) procedure for the determination of lead in zucchini, pomegranate, and lettuce has been established and developed by using flame atomic absorption spectrometer (FAAS). For UA-IL-DLLME procedure, 10 mL of the sample solution containing Pb2+ was adjusted to pH=5 in a glass test tube with a conical bottom; then, 120 μL of 1-Hexyl-3-methylimidazolium hexafluoro phosphate (CMIM)(PF6) was rapidly injected into the sample solution with a microsyringe. After that, the resulting cloudy mixture was treated by ultrasonic for 5 min, then the separation of two phases was obtained by centrifugation for 5 min at 3000 rpm and IL-phase diluted with 1 cc ethanol, and the analytes were determined by FAAS. The effect of different experimental parameters in the extraction step including: ionic liquid volume, sonication time and pH was studied and optimized simultaneously by using Response Surface Methodology (RSM) employing a central composite design (CCD). The optimal conditions were determined to be an ionic liquid volume of 120 μL, sonication time of 5 min, and pH=5. The linear ranges of the calibration curve for the determination by FAAS of lead were 0.1-4 ppm with R2=0.992. Under optimized conditions, the limit of detection (LOD) for lead was 0.062 μg.mL-1, the enrichment factor (EF) was 93, and the relative standard deviation (RSD) for lead was calculated as 2.29%. The levels of lead for pomegranate, zucchini, and lettuce were calculated as 2.88 μg.g-1, 1.54 μg.g-1, 2.18 μg.g-1, respectively. Therefore, this method has been successfully applied for the analysis of the content of lead in different food samples by FAAS. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dispersive%20liquid-liquid%20microextraction" title="Dispersive liquid-liquid microextraction">Dispersive liquid-liquid microextraction</a>, <a href="https://publications.waset.org/abstracts/search?q=Central%20composite%20design" title=" Central composite design"> Central composite design</a>, <a href="https://publications.waset.org/abstracts/search?q=Food%20samples" title=" Food samples"> Food samples</a>, <a href="https://publications.waset.org/abstracts/search?q=Flame%20atomic%20absorption%20spectrometry." title=" Flame atomic absorption spectrometry."> Flame atomic absorption spectrometry.</a> </p> <a href="https://publications.waset.org/abstracts/43911/ligandless-extraction-and-determination-of-trace-amounts-of-lead-in-pomegranate-zucchini-and-lettuce-samples-after-dispersive-liquid-liquid-microextraction-with-ultrasonic-bath-and-optimization-of-extraction-condition-with-rsm-design" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43911.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">283</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">33</span> Prevalence and Clinical Significance of Antiphospholipid Antibodies in COVID-19 Patients Admitted to Intensive Care Units</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Najim">Mostafa Najim</a>, <a href="https://publications.waset.org/abstracts/search?q=Alaa%20Rahhal"> Alaa Rahhal</a>, <a href="https://publications.waset.org/abstracts/search?q=Fadi%20Khir"> Fadi Khir</a>, <a href="https://publications.waset.org/abstracts/search?q=Safae%20Abu%20Yousef"> Safae Abu Yousef</a>, <a href="https://publications.waset.org/abstracts/search?q=Amer%20Aljundi"> Amer Aljundi</a>, <a href="https://publications.waset.org/abstracts/search?q=Feryal%20Ibrahim"> Feryal Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Aliaa%20Amer"> Aliaa Amer</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Soliman%20Mohamed"> Ahmed Soliman Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Samira%20Saleh"> Samira Saleh</a>, <a href="https://publications.waset.org/abstracts/search?q=Dekra%20Alfaridi"> Dekra Alfaridi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Mahfouz"> Ahmed Mahfouz</a>, <a href="https://publications.waset.org/abstracts/search?q=Sumaya%20Al-Yafei"> Sumaya Al-Yafei</a>, <a href="https://publications.waset.org/abstracts/search?q=Faraj%20Howady"> Faraj Howady</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamad%20Yahya%20%20Khatib"> Mohamad Yahya Khatib</a>, <a href="https://publications.waset.org/abstracts/search?q=Samar%20Alemadi"> Samar Alemadi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Coronavirus disease 2019 (COVID-19) increases the risk of coagulopathy among critically ill patients. Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19 induced coagulopathy, their clinical significance among critically ill patients with COVID-19 remains uncertain. Methods: This prospective observational study included patients with COVID-19 admitted to intensive care units (ICU) to evaluate the prevalence and clinical significance of aPLs, including anticardiolipin IgG/IgM, anti-β2-glycoprotein IgG/IgM, and lupus anticoagulant. The study outcomes included the prevalence of aPLs, a primary composite outcome of all-cause mortality, and arterial or venous thrombosis among aPLs positive patients versus aPLs negative patients during their ICU stay. Multiple logistic regression was used to assess the influence of aPLs on the primary composite outcome of mortality and thrombosis. Results: A total of 60 critically ill patients were enrolled. Of whom, 57 (95%) were male, with a mean age of 52.8 ± 12.2 years, and the majority were from Asia (68%). Twenty-two patients (37%) were found to have positive aPLs; of whom 21 patients were positive for lupus anticoagulant, whereas one patient was positive for anti-β2-glycoprotein IgG/IgM. The composite outcome of mortality and thrombosis during ICU did not differ among patients with positive aPLs compared to those with negative aPLs (4 (18%) vs. 6 (16%), aOR= 0.98, 95% CI 0.1-6.7; p-value= 0.986). Likewise, the secondary outcomes, including all-cause mortality, venous thrombosis, arterial thrombosis, discharge from ICU, time to mortality, and time to discharge from ICU, did not differ between those with positive aPLs upon ICU admission in comparison to patients with negative aPLs. Conclusion: The presence of aPLs does not seem to affect the outcomes of critically ill patients with COVID-19 in terms of all-cause mortality and thrombosis. Therefore, clinicians may not screen critically ill patients with COVID-19 for aPLs unless deemed clinically appropriate. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antiphospholipid%20antibodies" title="antiphospholipid antibodies">antiphospholipid antibodies</a>, <a href="https://publications.waset.org/abstracts/search?q=critically%20ill%20patients" title=" critically ill patients"> critically ill patients</a>, <a href="https://publications.waset.org/abstracts/search?q=coagulopathy" title=" coagulopathy"> coagulopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=coronavirus" title=" coronavirus"> coronavirus</a> </p> <a href="https://publications.waset.org/abstracts/131723/prevalence-and-clinical-significance-of-antiphospholipid-antibodies-in-covid-19-patients-admitted-to-intensive-care-units" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/131723.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">166</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">32</span> Determining Water Use Efficiency of Mung Bean (Vigna radiata L.) under Arid Climatic Conditions</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Awais%20Ahmad">Awais Ahmad</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Muhammad%20Selim"> Mostafa Muhammad Selim</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%20Abdullah%20Alderfasi"> Ali Abdullah Alderfasi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Water limitation is undoubtedly a critical environmental constraint limiting the crop production under arid and semiarid areas. Mung bean is susceptible to both drought and water logging stresses. Therefore, present study was conducted to assess the water deficit stress consequences of yield components and water use efficiency in Mung bean. A field experiment was conducted at Educational Farm, Crop Production Department, College of Food and Agricultural Sciences, Kind Saud University, Saudi Arabia. Trail comprised of four irrigation levels — total amount of irrigation divided into irrigation intervals — (3, 5, 7 and 9 days interval) and three Mung bean genotypes; Kawmay-1, VC-2010 and King from Egypt, Thailand and China respectively. Experiment was arranged under split plot design having irrigation as main while genotype as subplot treatment, and replicated thrice. Plant height, 100 seed weight, biological yield, seed yield, harvest index and water use efficiency were recorded at harvesting. Results revealed that decrease in irrigation have significantly hampered all the studied parameters. Mung bean genotypes have also shown significant differences for all parameters, whereas irrigation genotype interaction was highly significant for seed yield, harvest index and water use efficiency (WUE) while it was significant for biological yield. Plant height and 100 seed weight were recorded non-significant for irrigation genotype interaction. A statistically highly significant correlation among recorded parameters was observed. Minimum irrigation interval (3 days) significantly produced maximum values while VC-2010 comparatively performed better under low irrigation levels. It was concluded that Mung bean may be successfully adopted under Saudi Arabian climate but it needs high water or frequent irrigation, however, genotypic differences are a hope to develop some improved varieties with high water use efficiency. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mung%20bean" title="mung bean">mung bean</a>, <a href="https://publications.waset.org/abstracts/search?q=irrigation%20intervals" title=" irrigation intervals"> irrigation intervals</a>, <a href="https://publications.waset.org/abstracts/search?q=water%20use%20efficiency" title=" water use efficiency"> water use efficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=genotypes" title=" genotypes"> genotypes</a>, <a href="https://publications.waset.org/abstracts/search?q=yield" title=" yield"> yield</a> </p> <a href="https://publications.waset.org/abstracts/5159/determining-water-use-efficiency-of-mung-bean-vigna-radiata-l-under-arid-climatic-conditions" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/5159.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">274</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">31</span> Therapeutic Efficacy of Clompanus Pubescens Leaves Fractions via Downregulation of Neuronal Cholinesterases/NA⁺-K⁺ ATPase/IL-1 β and Improving the Neurocognitive and Antioxidants Status of Streptozotocin-Induced Diabetic Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amos%20Sunday%20Onikanni">Amos Sunday Onikanni</a>, <a href="https://publications.waset.org/abstracts/search?q=Bashir%20Lawal"> Bashir Lawal</a>, <a href="https://publications.waset.org/abstracts/search?q=Babatunji%20Emmanuel%20Oyinloye"> Babatunji Emmanuel Oyinloye</a>, <a href="https://publications.waset.org/abstracts/search?q=Gomaa%20Mostafa-Hedeab"> Gomaa Mostafa-Hedeab</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Alorabi"> Mohammed Alorabi</a>, <a href="https://publications.waset.org/abstracts/search?q=Simona%20Cavalu"> Simona Cavalu</a>, <a href="https://publications.waset.org/abstracts/search?q=Augustine%20O.%20Olusola"> Augustine O. Olusola</a>, <a href="https://publications.waset.org/abstracts/search?q=Chih-Hao%20Wang"> Chih-Hao Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Gaber%20El-Saber%20Batiha"> Gaber El-Saber Batiha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The increasing global burden of diabetes mellitus has called for the search for a therapeutic alternative that offers better activities and safety than conventional chemotherapy. Herein, we evaluated the neuroprotective and antioxidant properties of different fractions (ethyl acetate, N-butanol and residual aqueous) of Clompanus pubescens leaves in streptozotocin (STZ)-induced diabetic rats. Our results revealed a significant elevation in the levels of blood glucose, pro-inflammatory cytokines, lipid peroxidation, neuronal activities of acetylcholinesterase, butyrylcholinesterase, nitric oxide, epinephrine, norepinephrine, and Na+/K+-ATPase in diabetic non treated rats. In addition, decreased levels of enzymatic and non-enzymatic antioxidants were observed. Treatment with different fractions of C. pubescens leaves resulted in a significant reversal of the biochemical alteration and improved the neurocognitive deficit in STZ-induced diabetic rats. However, the ethyl-acetate fraction demonstrated higher activities than the other fractions and was characterized for its phytoconstituents, revealing the presence of Gallic acid (713.00 ppm), catechin (0.91 ppm), ferulic acid (0.98 ppm), rutin (59.82 ppm), quercetin (3.22 ppm) and kaempferol (4.07 ppm). Our molecular docking analysis revealed that these compounds exhibited different binding affinities and potentials for targeting BChE/AChE/ IL-1 β/Na+-K+-ATPase. However, only Kampferol and ferulic exhibited good drug-like, ADMET, and permeability properties suitable for use as a neuronal drug target agent. Hence, the ethyl-acetate fraction of C. pubescent leaves could be considered a source of promising bioactive metabolite for the treatment and management of cognitive impairments related to type II diabetes mellitus. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus" title="diabetes mellitus">diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=neuroprotective" title=" neuroprotective"> neuroprotective</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=pro-inflammatory%20cytokines" title=" pro-inflammatory cytokines"> pro-inflammatory cytokines</a> </p> <a href="https://publications.waset.org/abstracts/148959/therapeutic-efficacy-of-clompanus-pubescens-leaves-fractions-via-downregulation-of-neuronal-cholinesterasesna-k-atpaseil-1-v-and-improving-the-neurocognitive-and-antioxidants-status-of-streptozotocin-induced-diabetic-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/148959.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">117</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">30</span> IL-23, an Inflammatory Cytokine, Decreased by Shark Cartilage and Vitamin A Oral Treatment in Patient with Gastric Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Razieh%20Zarei">Razieh Zarei</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassan%20zm"> Hassan zm</a>, <a href="https://publications.waset.org/abstracts/search?q=Abolghasem%20Ajami"> Abolghasem Ajami</a>, <a href="https://publications.waset.org/abstracts/search?q=Darush%20Moslemi"> Darush Moslemi</a>, <a href="https://publications.waset.org/abstracts/search?q=Narges%20Afsary"> Narges Afsary</a>, <a href="https://publications.waset.org/abstracts/search?q=Amrollah%20Mostafa-zade"> Amrollah Mostafa-zade </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: IL-23 is responsible for the differentiation and expansion of Th17/ThIL-17 cells from naive CD4+ T cells. Therefore, may be IL-23/IL17 axis involve in a variety of allergic and autoimmune diseases, such as RA, MS, inflammatory bowel disease (IBD), and asthma. TGF-β is also share for the differentiation Th17 producing IL-17 and CD4+CD25+Foxp3hiT regulatory cells from naïve CD4+ T cells which are involved in the regulation of immune response, maintaining immunological self-tolerance and immune homeostasis ,and the control of autoimmunity and cancer surveillance. Therefore, T regulatory cells play a key role in autoimmunity, allergy, cancer, infectious disease, and the induction of transplantation tolerance. Vitamin A and it's derivatives (retinoids) inhibit or reverse the carcinogenic process in some types of cancers in oral cavity,head and neck, breast, skin, liver, and blood cells. Shark is a murine organism and its cartilage has antitumor peptides to prevent angiogenesis, in vitro. Our purpose is whether simultaneous oral treatment vitamin A and shark cartilage can modulate IL-23/IL-17 and CD4CD25Foxp3 T regulatory cell/TGF-β pathways and Th1/Th2 immunity in patients with gastric cancer. Materials and Methods: First investigated an imbalanced supernatant of cytokines exist in patients with gastric cancer by ELISA. Associated with cytokines measuring such as IL-23,IL-17,TGF-β,IL-4 and γ-IFN, then flow cytometry was employed to determine whether the peripheral blood mononuclear cells such as CD4+CD25+Foxp3highT regulatory cells in patients with gastric cancer were changed correspondingly. Results: An imbalance between IL-17 secretion and TGF-β/Foxp3 t regulatory cell pathway and so, Th1 immunity (γ-IFN production) and TH2 immunity (IL-4 secretion) was not seen in patients with gastric cancer treated by vitamin A and shark cartilage. But, the simultaneously presented down-regulation of IL-23 indicated, at least cytokine level. Conclusion: Il-23, as a pro-angiogenesis cytokine, probably, help to tumor growth. Hence, suggested that down-regulation of IL-23, at least cytokine level, is useful for anti-tumor immune responses in patients with gastric cancer. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IL-23%2FIL17%20axis" title="IL-23/IL17 axis">IL-23/IL17 axis</a>, <a href="https://publications.waset.org/abstracts/search?q=TGF-%CE%B2%2FCD4CD25Foxp3%20T%20regulatory%20pathway" title=" TGF-β/CD4CD25Foxp3 T regulatory pathway"> TGF-β/CD4CD25Foxp3 T regulatory pathway</a>, <a href="https://publications.waset.org/abstracts/search?q=%CE%B3-IFN" title=" γ-IFN"> γ-IFN</a>, <a href="https://publications.waset.org/abstracts/search?q=IL-4" title=" IL-4"> IL-4</a>, <a href="https://publications.waset.org/abstracts/search?q=shark%20cartilage%20and%20gastric%20cancer" title=" shark cartilage and gastric cancer"> shark cartilage and gastric cancer</a> </p> <a href="https://publications.waset.org/abstracts/11180/il-23-an-inflammatory-cytokine-decreased-by-shark-cartilage-and-vitamin-a-oral-treatment-in-patient-with-gastric-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11180.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">395</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">29</span> Saudi State Arabia’s Struggle for a Post-Rentier Regional Order</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Omair%20Anas">Omair Anas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Persian Gulf has been in turmoil for a long time since the colonial administration has handed over the role to the small and weak kings and emirs who were assured of protection in return of many economic and security promises to them. The regional order, Saudi Arabia evolved was a rentier regional order secured by an expansion of rentier economy and taking responsibility for much of the expenses of the regional order on behalf of relatively poor countries. The two oil booms helped the Saudi state to expand the 'rentier order' driven stability and bring the countries like Egypt, Jordan, Syria, and Palestine under its tutelage. The disruptive misadventure, however, came with Iran's proclamation of the Islamic Revolution in 1979 which it wanted to be exported to its 'un-Islamic and American puppet' Arab neighbours. For Saudi Arabia, even the challenge presented by the socialist-nationalist Arab dictators like Gamal Abdul Nasser and Hafez Al-Assad was not that much threatening to the Saudi Arabia’s then-defensive realism. In the Arab uprisings, the Gulf monarchies saw a wave of insecurity and Iran found it an opportune time to complete the revolutionary process it could not complete after 1979. An alliance of convenience and ideology between Iran and Islamist groups had the real potential to challenge both Saudi Arabia’s own security and its leadership in the region. The disruptive threat appeared at a time when the Saudi state had already sensed an impending crisis originating from the shifts in the energy markets. Low energy prices, declining global demands, and huge investments in alternative energy resources required Saudi Arabia to rationalize its economy according to changing the global political economy. The domestic Saudi reforms remained gradual until the death of King Abdullah in 2015. What is happening now in the region, the Qatar crisis, the Lebanon crisis and the Saudi-Iranian proxy war in Iraq, Syria, and Yemen has combined three immediate objectives, rationalising Saudi economy and most importantly, the resetting the Saudi royal power for Saudi Arabia’s longest-serving future King Mohammad bin Salman. The Saudi King perhaps has no time to wait and watch the power vacuum appearing because of Iran’s expansionist foreign policy. The Saudis appear to be employing an offensive realism by advancing a pro-active regional policy to counter Iran’s threatening influence amid disappearing Western security from the region. As the Syrian civil war is coming to a compromised end with ceding much ground to Iran-controlled militias, Hezbollah and Al-Hashad, the Saudi state has lost much ground in these years and the threat from Iranian proxies is more than a reality, more clearly in Bahrain, Iraq, Syria, and Yemen. This paper attempts to analyse the changing Saudi behaviour in the region, which, the author understands, is shaped by an offensive-realist approach towards finding a favourable security environment for the Saudi-led regional order, a post-rentier order perhaps. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=terrorism" title="terrorism">terrorism</a>, <a href="https://publications.waset.org/abstracts/search?q=Saudi%20Arabia" title=" Saudi Arabia"> Saudi Arabia</a>, <a href="https://publications.waset.org/abstracts/search?q=Rentier%20State" title=" Rentier State"> Rentier State</a>, <a href="https://publications.waset.org/abstracts/search?q=gulf%20crisis" title=" gulf crisis"> gulf crisis</a> </p> <a href="https://publications.waset.org/abstracts/90116/saudi-state-arabias-struggle-for-a-post-rentier-regional-order" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90116.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">136</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28</span> Influential Parameters in Estimating Soil Properties from Cone Penetrating Test: An Artificial Neural Network Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20G.%20Mahgoub">Ahmed G. Mahgoub</a>, <a href="https://publications.waset.org/abstracts/search?q=Dahlia%20H.%20Hafez"> Dahlia H. Hafez</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20A.%20Abu%20Kiefa"> Mostafa A. Abu Kiefa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Cone Penetration Test (CPT) is a common in-situ test which generally investigates a much greater volume of soil more quickly than possible from sampling and laboratory tests. Therefore, it has the potential to realize both cost savings and assessment of soil properties rapidly and continuously. The principle objective of this paper is to demonstrate the feasibility and efficiency of using artificial neural networks (ANNs) to predict the soil angle of internal friction (Φ) and the soil modulus of elasticity (E) from CPT results considering the uncertainties and non-linearities of the soil. In addition, ANNs are used to study the influence of different parameters and recommend which parameters should be included as input parameters to improve the prediction. Neural networks discover relationships in the input data sets through the iterative presentation of the data and intrinsic mapping characteristics of neural topologies. General Regression Neural Network (GRNN) is one of the powerful neural network architectures which is utilized in this study. A large amount of field and experimental data including CPT results, plate load tests, direct shear box, grain size distribution and calculated data of overburden pressure was obtained from a large project in the United Arab Emirates. This data was used for the training and the validation of the neural network. A comparison was made between the obtained results from the ANN's approach, and some common traditional correlations that predict Φ and E from CPT results with respect to the actual results of the collected data. The results show that the ANN is a very powerful tool. Very good agreement was obtained between estimated results from ANN and actual measured results with comparison to other correlations available in the literature. The study recommends some easily available parameters that should be included in the estimation of the soil properties to improve the prediction models. It is shown that the use of friction ration in the estimation of Φ and the use of fines content in the estimation of E considerable improve the prediction models. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=angle%20of%20internal%20friction" title="angle of internal friction">angle of internal friction</a>, <a href="https://publications.waset.org/abstracts/search?q=cone%20penetrating%20test" title=" cone penetrating test"> cone penetrating test</a>, <a href="https://publications.waset.org/abstracts/search?q=general%20regression%20neural%20network" title=" general regression neural network"> general regression neural network</a>, <a href="https://publications.waset.org/abstracts/search?q=soil%20modulus%20of%20elasticity" title=" soil modulus of elasticity"> soil modulus of elasticity</a> </p> <a href="https://publications.waset.org/abstracts/16780/influential-parameters-in-estimating-soil-properties-from-cone-penetrating-test-an-artificial-neural-network-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16780.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">415</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">27</span> Comparison of the Efficacy of Ketamine-Propofol versus Thiopental Sodium-Fentanyl in Procedural Sedation in the Emergency Department: A Randomized Double-Blind Clinical Trial</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Bahreini">Maryam Bahreini</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Talebi%20Garekani"> Mostafa Talebi Garekani</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatemeh%20Rasooli"> Fatemeh Rasooli</a>, <a href="https://publications.waset.org/abstracts/search?q=Atefeh%20Abdollahi"> Atefeh Abdollahi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Procedural sedation and analgesia have been desirable to handle painful procedures. The trend to find the agent with more efficacy and less complications is still controversial; thus, many sedative regimens have been studied. This study tried to assess the effectiveness and adverse effects of thiopental sodium-fentanyl with the known medication, ketamine-propofol for procedural sedation in the emergency department. Methods: Consenting patients were enrolled in this randomized double-blind trial to receive either 1:1 ketamine-propofol (KP) or thiopental-fentanyl (TF) 1:1 mg: Mg proportion on a weight-based dosing basis to reach the sedation level of American Society of Anesthesiologist class III/IV. The respiratory and hemodynamic complications, nausea and vomiting, recovery agitation, patient recall and satisfaction, provider satisfaction and recovery time were compared. The study was registered in Iranian randomized Control Trial Registry (Code: IRCT2015111325025N1). Results: 96 adult patients were included and randomized, 47 in the KP group and 49 in the TF group. 2.1% in the KP group and 8.1 % in the TF group experienced transient hypoxia leading to performing 4.2 % versus 8.1 % airway maneuvers for 2 groups, respectively; however, no statistically significant difference was observed between 2 combinations, and there was no report of endotracheal placement or further admission. Patient and physician satisfaction were significantly higher in the KP group. There was no difference in respiratory, gastrointestinal, cardiovascular and psychiatric adverse events, recovery time and patient recall of the procedure between groups. The efficacy and complications were not related to the type of procedure or patients’ smoking or addiction trends. Conclusion: Ketamine-propofol and thiopental-fentanyl combinations were effectively comparable although KP resulted in higher patient and provider satisfaction. It is estimated that thiopental fentanyl combination can be as potent and efficacious as ketofol with relatively similar incidence of adverse events in procedural sedation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adverse%20effects" title="adverse effects">adverse effects</a>, <a href="https://publications.waset.org/abstracts/search?q=conscious%20sedation" title=" conscious sedation"> conscious sedation</a>, <a href="https://publications.waset.org/abstracts/search?q=fentanyl" title=" fentanyl"> fentanyl</a>, <a href="https://publications.waset.org/abstracts/search?q=propofol" title=" propofol"> propofol</a>, <a href="https://publications.waset.org/abstracts/search?q=ketamine" title=" ketamine"> ketamine</a>, <a href="https://publications.waset.org/abstracts/search?q=safety" title=" safety"> safety</a>, <a href="https://publications.waset.org/abstracts/search?q=thiopental" title=" thiopental"> thiopental</a> </p> <a href="https://publications.waset.org/abstracts/77085/comparison-of-the-efficacy-of-ketamine-propofol-versus-thiopental-sodium-fentanyl-in-procedural-sedation-in-the-emergency-department-a-randomized-double-blind-clinical-trial" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77085.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">218</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">26</span> The Effect of Six-Weeks of Elastic Exercises with Reactionary Ropes on Nerve Conduction Velocity and Balance in Females with Multiple Sclerosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Sarabzadeh">Mostafa Sarabzadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Masoumeh%20Helalizadeh"> Masoumeh Helalizadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Seyyed%20Mahmoud%20Hejazi"> Seyyed Mahmoud Hejazi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Multiple Sclerosis is considered as diseases related to central nerve system, the chronic and progressive disease impress on sensory and motor function of people. Due to equilibrium problems in this patients that related to disorder of nerve conduction transmission from central nerve system to organs and the nature of elastic bands that can make changes in neuromuscular junctions and momentary actions, the aim of this research is evaluate elastic training effect by reactionary ropes on nerve conduction velocity (in lower and upper limb) and functional balance in female patients with Multiple Sclerosis. The study was a semi-experimental study that was performed based on pre and post-test method, The statistical community consisted of 16 women with MS in the age mean 25-40yrs, at low and intermediate levels of disease EDSS 1-4 (Expanded Disability Status Scale) that were divided randomly into elastic and control groups, so the training program of experimental group lasted six weeks, 3 sessions per week of elastic exercises with reactionary ropes. Electroneurography parameters (nerve conduction velocity- latency) of Upper and lower nerves (Median, Tibial, Sural, Peroneal) along with balance were investigated respectively by the Electroneurography system (ENG) and Timed up and go (TUG) functional test two times in before and after the training period. After that, To analyze the data were used of Dependent and Independent T-test (with sig level p<0.05). The results showed significant increase in nerve conduction velocity of Sural (p=0.001), Peroneal (p=0.01), Median (p=0.03) except Tibial and also development Latency Time of Tibial (p= 0), Peroneal (p=0), Median (p=0) except Sural. The TUG test showed significant decreases in execution time too (p=0.001). Generally, based on what the obtained data can indicate, modern training with elastic bands can contribute to enhanced nerve conduction velocity and balance in neurosis patients (MS) so lead to reduce problems, promotion of mobility and finally more life expectancy in these patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=balance" title="balance">balance</a>, <a href="https://publications.waset.org/abstracts/search?q=elastic%20bands" title=" elastic bands"> elastic bands</a>, <a href="https://publications.waset.org/abstracts/search?q=multiple%20sclerosis" title=" multiple sclerosis"> multiple sclerosis</a>, <a href="https://publications.waset.org/abstracts/search?q=nerve%20conduction" title=" nerve conduction"> nerve conduction</a>, <a href="https://publications.waset.org/abstracts/search?q=velocity" title=" velocity"> velocity</a> </p> <a href="https://publications.waset.org/abstracts/69414/the-effect-of-six-weeks-of-elastic-exercises-with-reactionary-ropes-on-nerve-conduction-velocity-and-balance-in-females-with-multiple-sclerosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69414.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">216</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">25</span> Model Order Reduction of Complex Airframes Using Component Mode Synthesis for Dynamic Aeroelasticity Load Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Paul%20V.%20Thomas">Paul V. Thomas</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20S.%20A.%20Elsayed"> Mostafa S. A. Elsayed</a>, <a href="https://publications.waset.org/abstracts/search?q=Denis%20Walch"> Denis Walch</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Airframe structural optimization at different design stages results in new mass and stiffness distributions which modify the critical design loads envelop. Determination of aircraft critical loads is an extensive analysis procedure which involves simulating the aircraft at thousands of load cases as defined in the certification requirements. It is computationally prohibitive to use a Global Finite Element Model (GFEM) for the load analysis, hence reduced order structural models are required which closely represent the dynamic characteristics of the GFEM. This paper presents the implementation of Component Mode Synthesis (CMS) method for the generation of high fidelity Reduced Order Model (ROM) of complex airframes. Here, sub-structuring technique is used to divide the complex higher order airframe dynamical system into a set of subsystems. Each subsystem is reduced to fewer degrees of freedom using matrix projection onto a carefully chosen reduced order basis subspace. The reduced structural matrices are assembled for all the subsystems through interface coupling and the dynamic response of the total system is solved. The CMS method is employed to develop the ROM of a Bombardier Aerospace business jet which is coupled with an aerodynamic model for dynamic aeroelasticity loads analysis under gust turbulence. Another set of dynamic aeroelastic loads is also generated employing a stick model of the same aircraft. Stick model is the reduced order modelling methodology commonly used in the aerospace industry based on stiffness generation by unitary loading application. The extracted aeroelastic loads from both models are compared against those generated employing the GFEM. Critical loads Modal participation factors and modal characteristics of the different ROMs are investigated and compared against those of the GFEM. Results obtained show that the ROM generated using Craig Bampton CMS reduction process has a superior dynamic characteristics compared to the stick model. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=component%20mode%20synthesis" title="component mode synthesis">component mode synthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=craig%20bampton%20reduction%20method" title=" craig bampton reduction method"> craig bampton reduction method</a>, <a href="https://publications.waset.org/abstracts/search?q=dynamic%20aeroelasticity%20analysis" title=" dynamic aeroelasticity analysis"> dynamic aeroelasticity analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=model%20order%20reduction" title=" model order reduction"> model order reduction</a> </p> <a href="https://publications.waset.org/abstracts/93526/model-order-reduction-of-complex-airframes-using-component-mode-synthesis-for-dynamic-aeroelasticity-load-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/93526.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">209</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">24</span> Structural Development and Multiscale Design Optimization of Additively Manufactured Unmanned Aerial Vehicle with Blended Wing Body Configuration</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Malcolm%20Dinovitzer">Malcolm Dinovitzer</a>, <a href="https://publications.waset.org/abstracts/search?q=Calvin%20Miller"> Calvin Miller</a>, <a href="https://publications.waset.org/abstracts/search?q=Adam%20Hacker"> Adam Hacker</a>, <a href="https://publications.waset.org/abstracts/search?q=Gabriel%20Wong"> Gabriel Wong</a>, <a href="https://publications.waset.org/abstracts/search?q=Zach%20Annen"> Zach Annen</a>, <a href="https://publications.waset.org/abstracts/search?q=Padmassun%20Rajakareyar"> Padmassun Rajakareyar</a>, <a href="https://publications.waset.org/abstracts/search?q=Jordan%20Mulvihill"> Jordan Mulvihill</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20S.A.%20ElSayed"> Mostafa S.A. ElSayed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The research work presented in this paper is developed by the Blended Wing Body (BWB) Unmanned Aerial Vehicle (UAV) team, a fourth-year capstone project at Carleton University Department of Mechanical and Aerospace Engineering. Here, a clean sheet UAV with BWB configuration is designed and optimized using Multiscale Design Optimization (MSDO) approach employing lattice materials taking into consideration design for additive manufacturing constraints. The BWB-UAV is being developed with a mission profile designed for surveillance purposes with a minimum payload of 1000 grams. To demonstrate the design methodology, a single design loop of a sample rib from the airframe is shown in details. This includes presentation of the conceptual design, materials selection, experimental characterization and residual thermal stress distribution analysis of additively manufactured materials, manufacturing constraint identification, critical loads computations, stress analysis and design optimization. A dynamic turbulent critical load case was identified composed of a 1-g static maneuver with an incremental Power Spectral Density (PSD) gust which was used as a deterministic design load case for the design optimization. 2D flat plate Doublet Lattice Method (DLM) was used to simulate aerodynamics in the aeroelastic analysis. The aerodynamic results were verified versus a 3D CFD analysis applying Spalart-Allmaras and SST k-omega turbulence to the rigid UAV and vortex lattice method applied in the OpenVSP environment. Design optimization of a single rib was conducted using topology optimization as well as MSDO. Compared to a solid rib, weight savings of 36.44% and 59.65% were obtained for the topology optimization and the MSDO, respectively. These results suggest that MSDO is an acceptable alternative to topology optimization in weight critical applications while preserving the functional requirements. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=blended%20wing%20body" title="blended wing body">blended wing body</a>, <a href="https://publications.waset.org/abstracts/search?q=multiscale%20design%20optimization" title=" multiscale design optimization"> multiscale design optimization</a>, <a href="https://publications.waset.org/abstracts/search?q=additive%20manufacturing" title=" additive manufacturing"> additive manufacturing</a>, <a href="https://publications.waset.org/abstracts/search?q=unmanned%20aerial%20vehicle" title=" unmanned aerial vehicle"> unmanned aerial vehicle</a> </p> <a href="https://publications.waset.org/abstracts/93519/structural-development-and-multiscale-design-optimization-of-additively-manufactured-unmanned-aerial-vehicle-with-blended-wing-body-configuration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/93519.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">374</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">23</span> Effect of Amiodarone on the Thyroid Gland of Adult Male Albino Rat and the Possible Protective Role of Vitamin E Supplementation: A Histological and Ultrastructural Study </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20Abdulla%20Labib">Ibrahim Abdulla Labib</a>, <a href="https://publications.waset.org/abstracts/search?q=Medhat%20Mohamed%20Morsy"> Medhat Mohamed Morsy</a>, <a href="https://publications.waset.org/abstracts/search?q=Gamal%20Hosny"> Gamal Hosny</a>, <a href="https://publications.waset.org/abstracts/search?q=Hanan%20Dawood%20Yassa"> Hanan Dawood Yassa</a>, <a href="https://publications.waset.org/abstracts/search?q=Gaber%20Hassan"> Gaber Hassan </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Amiodarone is a very effective drug, widely used for arrhythmia. Unfortunately it has many side effects involving many organs especially thyroid gland. The current work was conducted to elucidate the effect of amiodarone on the thyroid gland and the possible protective role of vitamin E. Fifty adult male albino rats weighed 200 – 250 grams were divided into five groups; ten rats each. Group I (Control): Five rats were sacrificed after three weeks and five rats were sacrificed after six weeks. Group II (Sham control): Each rat received sunflower oil orally; the solvent of vitamin E for three weeks. Group III (Amiodarone-treated): each rat received an oral dose of amiodarone; 150 mg/kg/day for three weeks. Group IV (Recovery): Each rat received amiodarone as group III then the drug was stopped for three weeks to evaluate recovery. Group V (Amiodarone + Vitamin E-treated): Each rat received amiodarone as group III followed by 100 mg/kg/day vitamin E orally for three weeks. Thyroid gland of the sacrificed animals were dissected out and prepared for light and electron microscopic studies. Amiodarone administration resulted in loss of normal follicular architecture as many follicles appeared either shrunken, empty or contained scanty pale colloid. Some follicles appeared lined by more than one layer of cells while others showed interruption of their membrane. Masson's Trichrome stained sections showed increased collagen fibers in between the thyroid follicles. Ultrastructurally, the apical border of the follicular cells showed few irregular detached microvilli. The nuclei of the follicular cells were almost irregular with chromatin condensation. The cytoplasm of most follicular cells revealed numerous dilated rough endoplasmic reticulum with numerous lysosomes. After three weeks of stopping amiodarone, the follicles were nearly regular in outline. Some follicles were filled with homogenous eosinophilic colloid and others had shrunken pale colloid or were empty. Some few follicles showed exfoliated cells in their lumina and others were still lined by more than one layer of follicular cells. Moderate amounts of collagen fibers were observed in-between thyroid follicles. Ultrastructurally, many follicular cells had rounded euchromatic nucleui, moderate number of lysosomes and moderately dilated rough endoplasmic reticulum. However, few follicular cells still showing irregular nucleui, dilated rough endoplasmic reticulum and many cytoplasmic vacuoles. Administration of vitamin E with amiodarone for three weeks resulted in obvious structural improvement. Most of the follicles were lined by a single layer of cuboidal cells and the lumina were filled with homogenous eosinophilic colloid with very few vacuolations. The majority of follicular cells had rounded nuclei with occasional detection of ballooned cells and dark nuclei. Scanty collagen fibers were detected among thyroid follicles. Ultrastructurally, most follicular cells exhibited rounded euchromatic nuclei with few short microvilli were projecting into the colloid. Few lysosomes were also noticed. It was concluded that amiodarone administration leads to many adverse histological changes in the thyroid gland. Some of these changes are reversible during the recovery period however concomitant vitamin E administration with amiodarone has a major protective role in preventing many of these changes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=amiodarone" title="amiodarone">amiodarone</a>, <a href="https://publications.waset.org/abstracts/search?q=recovery" title=" recovery"> recovery</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrastructure" title=" ultrastructure"> ultrastructure</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20E." title=" vitamin E."> vitamin E.</a> </p> <a href="https://publications.waset.org/abstracts/26961/effect-of-amiodarone-on-the-thyroid-gland-of-adult-male-albino-rat-and-the-possible-protective-role-of-vitamin-e-supplementation-a-histological-and-ultrastructural-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/26961.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">351</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">22</span> Remote Sensing Application in Environmental Researches: Case Study of Iran Mangrove Forests Quantitative Assessment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Neda%20Orak">Neda Orak</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Zarei"> Mostafa Zarei </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Environmental assessment is an important session in environment management. Since various methods and techniques have been produces and implemented. Remote sensing (RS) is widely used in many scientific and research fields such as geology, cartography, geography, agriculture, forestry, land use planning, environment, etc. It can show earth surface objects cyclical changes. Also, it can show earth phenomena limits on basis of electromagnetic reflectance changes and deviations records. The research has been done on mangrove forests assessment by RS techniques. Mangrove forests quantitative analysis in Basatin and Bidkhoon estuaries was the aim of this research. It has been done by Landsat satellite images from 1975- 2013 and match to ground control points. This part of mangroves are the last distribution in northern hemisphere. It can provide a good background to improve better management on this important ecosystem. Landsat has provided valuable images to earth changes detection to researchers. This research has used MSS, TM, +ETM, OLI sensors from 1975, 1990, 2000, 2003-2013. Changes had been studied after essential corrections such as fix errors, bands combination, georeferencing on 2012 images as basic image, by maximum likelihood and IPVI Index. It was done by supervised classification. 2004 google earth image and ground points by GPS (2010-2012) was used to compare satellite images obtained changes. Results showed mangrove area in bidkhoon was 1119072 m2 by GPS and 1231200 m2 by maximum likelihood supervised classification and 1317600 m2 by IPVI in 2012. Basatin areas is respectively: 466644 m2, 88200 m2, 63000 m2. Final results show forests have been declined naturally. It is due to human activities in Basatin. The defect was offset by planting in many years. Although the trend has been declining in recent years again. So, it mentioned satellite images have high ability to estimation all environmental processes. This research showed high correlation between images and indexes such as IPVI and NDVI with ground control points. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=IPVI%20index" title="IPVI index">IPVI index</a>, <a href="https://publications.waset.org/abstracts/search?q=Landsat%20sensor" title=" Landsat sensor"> Landsat sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=maximum%20likelihood%20supervised%20classification" title=" maximum likelihood supervised classification"> maximum likelihood supervised classification</a>, <a href="https://publications.waset.org/abstracts/search?q=Nayband%20National%20Park" title=" Nayband National Park"> Nayband National Park</a> </p> <a href="https://publications.waset.org/abstracts/41430/remote-sensing-application-in-environmental-researches-case-study-of-iran-mangrove-forests-quantitative-assessment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41430.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">293</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">21</span> The Voiceless Dental- Alveolar Common Augment in Arabic and Other Semitic Languages, a Morphophonemic Comparison</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tarek%20Soliman%20Mostafa%20Soliman%20Al-Nana%27i">Tarek Soliman Mostafa Soliman Al-Nana'i</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There are non-steady voiced augments in the Semitic languages, and in the morphological and structural augmentation, two sounds were augments in all Semitic languages at the level of the spoken language and two letters at the level of the written language, which are the hamza and the ta’. This research studies only the second of them; Therefore, we defined it as “The Voiceless Dental- alveolar common augment” (VDACA) to distinguish it from the glottal sound “Hamza”, first, middle, or last, in a noun or in a verb, in Arabic and its equivalent in the Semitic languages. What is meant by “VDACA” is the ta’ that is in addition to the root of the word at the morphological level: the word “voiceless” takes out the voiced sounds that we studied before, and the “dental- alveolar common augment” takes out the laryngeal sound of them, which is the “Hamza”: and the word “common” brings out the uncommon voiceless sounds, which are sīn, shīn, and hā’. The study is limited to the ta' alone among the Arabic sounds, and this title faced a problem in identifying it with the ta'. Because the designation of the ta is not the same in most Semitic languages. Hebrew, for example, has “tav” and is pronounced with the voiced fa (v), which is not in Arabic. It is called different names in other Semitic languages, such as “taw” or “tAu” in old Syriac. And so on. This goes hand in hand with the insistence on distance from the written level and the reference to the phonetic aspect in this study that is closely and closely linked to the morphological level. Therefore, the study is “morphophonemic”. What is meant by Semitic languages in this study are the following: Akkadian, Ugaritic, Hebrew, Syriac, Mandaean, Ge'ez, and Amharic. The problem of the study is the agreement or difference between these languages in the position of that augment, first, middle, or last. And in determining the distinguishing characteristics of each language from the other. As for the study methodology, it is determined by the comparative approach in Semitic languages, which is based on the descriptive approach for each language. The study is divided into an introduction, four sections, and a conclusion: Introduction: It included the subject of the study, its importance, motives, problem, methodology, and division. The first section: VDACA as a non-common phoneme. The second: VDACA as a common phoneme. The third: VDACA as a functional morpheme. The fourth section: Commentary and conclusion with the most important results. The positions of VDACA in Arabic and other Semitic languages, and in nouns and verbs, were limited to first, middle, and last. The research identified the individual addition, which is common with other augments, and the research proved that this augmentation is constant in all Semitic languages, but there are characteristics that distinguish each language from the other. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=voiceless%20-" title="voiceless -">voiceless -</a>, <a href="https://publications.waset.org/abstracts/search?q=dental-%20alveolar" title=" dental- alveolar"> dental- alveolar</a>, <a href="https://publications.waset.org/abstracts/search?q=augment" title=" augment"> augment</a>, <a href="https://publications.waset.org/abstracts/search?q=Arabic%20-%20semitic%20languages" title=" Arabic - semitic languages"> Arabic - semitic languages</a> </p> <a href="https://publications.waset.org/abstracts/173622/the-voiceless-dental-alveolar-common-augment-in-arabic-and-other-semitic-languages-a-morphophonemic-comparison" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173622.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">73</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> Isolation, Identification and Measurement of Cottonseed Oil Gossypol in the Treatment of Drug-Resistant Cutaneous Leishmaniasis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sara%20Taghdisi">Sara Taghdisi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mehrosadat%20Mirmohammadi"> Mehrosadat Mirmohammadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Mokhtarian"> Mostafa Mokhtarian</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Hossein%20Pazandeh"> Mohammad Hossein Pazandeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Leishmaniasis is one of the 10 most important diseases of the World Health Organization with health problems in more than 90 countries. Over one billion people are at risk of these diseases on almost every continent. The present human study was performed to evaluate the therapeutic effect of cotton plant on cutaneous leishmaniasis leision. firstly, the cotton seeds were cleaned and grinded to smaller particles. In the second step, the seeds were oiled by cold press method. In order to separate bioactive compound, after saponification of the oil, its gossypol was hydrolyzed and crystalized. finally, the therapeutic effect of Cottonseed Oil on cutaneous leishmaniasis was investigated. In the current project, Gossypol was extracted with a liquid-liquid extraction method in 120 minutes in the presence of Phosphoric acid from the cotton seed oil of Golestan beach varieties, then got crystallized in darkness using Acetic acid and isolated as Gossypol Acetic acid. The efficiency of the extracted crystal was obtained at 1.28±0.12. the cotton plant could be efficient in the treatment of Cutaneous leishmaniasis. This double-blind randomized controlled clinical trial was performed on 88 cases of leishmaniasis wounds. Patients were randomly divided into two groups of 44 cases. two groups received conventional treatment. In addition to the usual treatment (glucantime), the first group received cottonseed oil and the control group received placebo. The results of the present study showed that the surface of lesion before the intervention and in the first to fourth weeks after the intervention was not significantly different between the two groups (P-value> 0.05). But the surface of lesion in the Intervention group in the eighth and twelfth weeks was lower than the control group (P-value <0.05). This study showed that the improvement of leishmaniasis lesion using topical cotton plant mark in the eighth and twelfth weeks after the intervention was significantly more than the control group. Considering the most common chemical drugs for Cutaneous leishmaniasis treatment are sodium stibogluconate, and meglumine antimonate, which not only have relatively many side effects, but also some species of the Leishmania genus have become resistant to them. Therefore, a plant base bioactive compound such as cottonseed oil can be useful whit fewer side effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cottonseed%20oil" title="cottonseed oil">cottonseed oil</a>, <a href="https://publications.waset.org/abstracts/search?q=crystallization" title=" crystallization"> crystallization</a>, <a href="https://publications.waset.org/abstracts/search?q=gossypol" title=" gossypol"> gossypol</a>, <a href="https://publications.waset.org/abstracts/search?q=leishmaniasis" title=" leishmaniasis"> leishmaniasis</a> </p> <a href="https://publications.waset.org/abstracts/184861/isolation-identification-and-measurement-of-cottonseed-oil-gossypol-in-the-treatment-of-drug-resistant-cutaneous-leishmaniasis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184861.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">60</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> The Yield of Neuroimaging in Patients Presenting to the Emergency Department with Isolated Neuro-Ophthalmological Conditions</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dalia%20El%20Hadi">Dalia El Hadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Alaa%20Bou%20Ghannam"> Alaa Bou Ghannam</a>, <a href="https://publications.waset.org/abstracts/search?q=Hala%20Mostafa"> Hala Mostafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Hana%20%20Mansour"> Hana Mansour</a>, <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20Hashim"> Ibrahim Hashim</a>, <a href="https://publications.waset.org/abstracts/search?q=Soubhi%20Tahhan"> Soubhi Tahhan</a>, <a href="https://publications.waset.org/abstracts/search?q=Tharwat%20El%20Zahran"> Tharwat El Zahran</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Neuro-ophthalmological emergencies require prompt assessment and management to avoid vision or life-threatening sequelae. Some would require neuroimaging. Most commonly used are the CT and MRI of the Brain. They can be over-used when not indicated. Their yield remains dependent on multiple factors relating to the clinical scenario. Methods: A retrospective cross-sectional study was conducted by reviewing the electronic medical records of patients presenting to the Emergency Department (ED) with isolated neuro-ophthalmologic complaints. For each patient, data were collected on the clinical presentation, whether neuroimaging was performed (and which type), and the result of neuroimaging. Analysis of the performed neuroimaging was made, and its yield was determined. Results: A total of 211 patients were reviewed. The complaints or symptoms at presentation were: blurry vision, change in the visual field, transient vision loss, floaters, double vision, eye pain, eyelid droop, headache, dizziness and others such as nausea or vomiting. In the ED, a total of 126 neuroimaging procedures were performed. Ninety-four imagings (74.6%) were normal, while 32 (25.4%) had relevant abnormal findings. Only 2 symptoms were significant for abnormal imaging: blurry vision (p-value= 0.038) and visual field change (p-value= 0.014). While 4 physical exam findings had significant abnormal imaging: visual field defect (p-value= 0.016), abnormal pupil reactivity (p-value= 0.028), afferent pupillary defect (p-value= 0.018), and abnormal optic disc exam (p-value= 0.009). Conclusion: Risk indicators for abnormal neuroimaging in the setting of neuro-ophthalmological emergencies are blurred vision or changes in the visual field on history taking. While visual field irregularities, abnormal pupil reactivity with or without afferent pupillary defect, or abnormal optic discs, are risk factors related to physical testing. These findings, when present, should sway the ED physician towards neuroimaging but still individualizing each case is of utmost importance to prevent time-consuming, resource-draining, and sometimes unnecessary workup. In the end, it suggests a well-structured patient-centered algorithm to be followed by ED physicians. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=emergency%20department" title="emergency department">emergency department</a>, <a href="https://publications.waset.org/abstracts/search?q=neuro-ophthalmology" title=" neuro-ophthalmology"> neuro-ophthalmology</a>, <a href="https://publications.waset.org/abstracts/search?q=neuroimaging" title=" neuroimaging"> neuroimaging</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20indicators" title=" risk indicators"> risk indicators</a> </p> <a href="https://publications.waset.org/abstracts/133967/the-yield-of-neuroimaging-in-patients-presenting-to-the-emergency-department-with-isolated-neuro-ophthalmological-conditions" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133967.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">179</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> Diabetes and Medical Plant's Treatment: Ethnobotanical Studies Carried out in Morocco</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jamila%20Fakchich">Jamila Fakchich</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Jamila%20Lazaar%20Elachouri"> Mostafa Jamila Lazaar Elachouri</a>, <a href="https://publications.waset.org/abstracts/search?q=Lakhder%20Fakchich"> Lakhder Fakchich</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatna%20Ouali"> Fatna Ouali</a>, <a href="https://publications.waset.org/abstracts/search?q=Abd%20Errazzak%20Belkacem"> Abd Errazzak Belkacem</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diabetes is a chronic metabolic disease that has a significant impact on the health, quality of life, and life expectancy of patients as well as the health care system. By its nature diabetes, is a multisystem disease with wide-ranging complication that span nearly all region of the body. This epidemic problem, however, is not unique to the industrialized society, but has also hardly struck the developing countries. In Morocco, as developing country, there is an epidemic rise in diabetes, with ensuing concern about the management and control of this disease; it began a chronic burdensome disease of largely middle-aged and elderly people, with a long course and serious complications often resulting in high death-rate, the treatment of diabetes spent vast amount of resources including medicines, diets, physical training. Treatment of this disease is considered problematic due to the lack of effective and safe drugs capable of inducing sustained clinical, biochemical, and histological cure. In Moroccan society, the phytoremedies are some times the only affordable sources of healthcare, particularly for the people in remote areas. In this paper, we present a synthesis work obtained from the ethnobotanical data reported in different specialized journals. A Synthesis of four published ethnobotanical studies that have been carried out in different region of Morocco by different team seekers during the period from 1997 to 2015. Medicinal plants inventoried by different seekers in four Moroccan’s areas have been regrouped and codified, then, Factorial Analysis (FA) and Principal Components Analysis (PCA) are used to analyse the aggregated data from the four studies and plants are classified according to their frequency of use by population. Our work deals with an attempt to gather information on some traditional uses of medicinal plants from different regions of Morocco, also, it was designed to give a set of medicinal plants commonly used by Moroccan people in the treatment of diabetes; In this paper, we intended to provide a basic knowledge about plant species used by Moroccan society for treatment of diabetes. One of the most interesting aspects of this type of works is to assess the relative cultural importance of medicinal plants for specific illnesses and exploring its usefulness in the context of diabetes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Morocco" title="Morocco">Morocco</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title=" medicinal plants"> medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=ethnobotanical" title=" ethnobotanical"> ethnobotanical</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes" title=" diabetes"> diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=phytoremedies" title=" phytoremedies"> phytoremedies</a> </p> <a href="https://publications.waset.org/abstracts/40849/diabetes-and-medical-plants-treatment-ethnobotanical-studies-carried-out-in-morocco" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40849.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">332</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Tension-Free Vaginal Tape Secur (TVT Secur) versus Tension-Free Vaginal Tape-Obturator (TVT-O) from inside to outside in Surgical Management of Genuine Stress Urinary Incontinence</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20Mohamed%20Ibrahim%20Hassanin">Ibrahim Mohamed Ibrahim Hassanin</a>, <a href="https://publications.waset.org/abstracts/search?q=Hany%20Hassan%20Mostafa"> Hany Hassan Mostafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Mona%20Mohamed%20Shaban"> Mona Mohamed Shaban</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahlam%20El%20Said%20Kamel"> Ahlam El Said Kamel</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: New so-called minimally invasive devices have been developed to limit groin pain after sling placement for treatment of stress urinary incontinence (SUI) to minimize the risk of postoperative pain and organ perforation. A new generation of suburethral slings was described that avoided skin incision to pull out and tension the sling. Evaluation of this device through prospective short-term series has shown controversial results compared with other tension-free techniques. The aim of this study is to compare success rates and complications for tension-free vaginal tape secur (TVT secur) and trans-obturator sub urethral tape inside-out technique (TVT-O) for treatment of stress urinary incontinence (SUI). Materials and Methods: Fifty patients with genuine SUI were divided into two groups: group S (n=25) were operated upon using (TVT secur) and group O (n=25) were operated upon using trans-obturator suburethral tape inside-out technique (TVT-O). Success rate, quality of life and postoperative complications such as groin pain, urgency, urine retention and vaginal tape erosion were reported in both groups at one, three, and six months after surgery. Results: As regards objective cure rate at one, three, six months intervals; there was a significant difference between group S (56%, 64%, and 60%), and group O (80%, 88%, and 88%) respectively (P <0.05). As regards subjective cure rate at one, three, six months intervals; there was a significant difference between group S (44%, 44%, and 48%), and group O (76%, 80%, and 80%) respectively (P <0.05). Quality of life (QoL) parameters improved significantly in cured patients with no difference between both groups. As regards complications, group O had a higher frequency of complications than group S; groin pain (12% vs 12% p= 0.05), urgency (4% (1 case) vs 0%), urine retention (8% (2 cases) vs 0%), vaginal tape erosion (4% (1 case) vs 0%). No cases were complicated with wound infection. Conclusion: Compared to TVT secur, TVT-O showed higher subjective and objective cure rates after six months but higher rate of complications. Both techniques were comparable as regards improvement of quality of life after surgery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress%20urinary%20incontinence" title="stress urinary incontinence">stress urinary incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=trans-vaginal%20tape-obturator" title=" trans-vaginal tape-obturator"> trans-vaginal tape-obturator</a>, <a href="https://publications.waset.org/abstracts/search?q=TVT%20Secur" title=" TVT Secur"> TVT Secur</a>, <a href="https://publications.waset.org/abstracts/search?q=TVT-O" title=" TVT-O"> TVT-O</a> </p> <a href="https://publications.waset.org/abstracts/8928/tension-free-vaginal-tape-secur-tvt-secur-versus-tension-free-vaginal-tape-obturator-tvt-o-from-inside-to-outside-in-surgical-management-of-genuine-stress-urinary-incontinence" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8928.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">359</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> Investigating the Role of Supplier Involvement in the Design Process as an Approach for Enhancing Building Maintainability</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kamal%20Ahmed">Kamal Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Othman%20Ayman"> Othman Ayman</a>, <a href="https://publications.waset.org/abstracts/search?q=Refat%20Mostafa"> Refat Mostafa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The post-construction phase represents a critical milestone in the project lifecycle. This is because design errors and omissions, as well as construction defects, are examined during this phase. The traditional procurement approaches that are commonly adopted in construction projects separate design from construction, which ultimately inhibits contractors, suppliers and other parties from providing the design team with constructive comments and feedback to improve the project design. As a result, a lack of considering maintainability aspects during the design process results in increasing maintenance and operation costs as well as reducing building performance. This research aims to investigate the role of Early Supplier Involvement (ESI) in the design process as an approach to enhancing building maintainability. In order to achieve this aim, a research methodology consisting of a literature review, case studies and a survey questionnaire was designed to accomplish four objectives. Firstly, a literature review was used to examine the concepts of building maintenance, maintainability, the design process and ESI. Secondly, three case studies were presented and analyzed to investigate the role of ESI in enhancing building maintainability during the design process. Thirdly, a survey questionnaire was conducted with a representative sample of Architectural Design Firms (ADFs) in Egypt to investigate their perception and application of ESI towards enhancing building maintainability during the design process. Finally, the research developed a framework to facilitate ESI in the design process in ADFs in Egypt. Data analysis showed that the ‘Difficulty of trusting external parties and sharing information with transparency’ was ranked the highest challenge of ESI in ADFs in Egypt, followed by ‘Legal competitive advantage restrictions’. Moreover, ‘Better estimation for operation and maintenance costs’ was ranked the highest contribution of ESI towards enhancing building maintainability, followed by ‘Reduce the number of operation and maintenance problems or reworks’. Finally, ‘Innovation, technical expertise, and competence’ was ranked the highest supplier’s selection criteria, while ‘paying consultation fees for offering advice and recommendations to the design team’ was ranked the highest form of supplier’s remuneration. The proposed framework represents a synthesis that is creative in thought and adds value to the knowledge in a manner that has not previously occurred. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=maintenance" title="maintenance">maintenance</a>, <a href="https://publications.waset.org/abstracts/search?q=building%20maintainability" title=" building maintainability"> building maintainability</a>, <a href="https://publications.waset.org/abstracts/search?q=building%20life%20cycle%20cost%20%28ICC%29" title=" building life cycle cost (ICC)"> building life cycle cost (ICC)</a>, <a href="https://publications.waset.org/abstracts/search?q=material%20supplier" title=" material supplier"> material supplier</a> </p> <a href="https://publications.waset.org/abstracts/185550/investigating-the-role-of-supplier-involvement-in-the-design-process-as-an-approach-for-enhancing-building-maintainability" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185550.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">47</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Phosphate Tailings in View of a Better Waste Disposal And/or Valorization: Case of Tunisian Phosphates Mines</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mouna%20Ettoumi">Mouna Ettoumi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jouini%20Marouen"> Jouini Marouen</a>, <a href="https://publications.waset.org/abstracts/search?q=Carmen%20Mihaela%20Neculita"> Carmen Mihaela Neculita</a>, <a href="https://publications.waset.org/abstracts/search?q=Salah%20Bouhlel"> Salah Bouhlel</a>, <a href="https://publications.waset.org/abstracts/search?q=Lucie%20Coudert"> Lucie Coudert</a>, <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Benzaazoua"> Mostafa Benzaazoua</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20Taha"> Y. Taha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the context of sustainable development and circular economy, waste valorization is considered a promising alternative to overcome issues related to their disposal or elimination. The aim of this study is to evaluate the potential use of phosphate sludges (tailings) from the Kef Shfeir mine site (Gafsa, Tunisia) as an alternative material in the production of fired bricks. To do so, representative samples of raw phosphate treatment sludges were collected and characterized for their physical, chemical, mineralogical and environmental characteristics. Then, the raw materials were baked at different temperatures (900°C, 1000°C, and 1100°C) for bricks making. Afterward, fired bricks were characterized for their physical (particle size distribution, density, and plasticity), chemical (XRF and digestion), mineralogical (XRD) and mechanical (flexural strength) properties as well as for their environmental behavior (TCLP, SPLP, and CTEU-9) to ensure whether they meet the required construction standards. Results showed that the raw materials had low density (2.47g/cm 3), were non-plastic and were mainly composed of fluoroapatite (15.6%), calcite (23.1%) and clays (22.2% - mainly as heulandite, vermiculite and palygorskite). With respect to the environmental behavior, all metals (e.g., Pb, Zn, As, Cr, Ba, Cd) complied with the requirements set by the USEPA. In addition, fired bricks had varying porosity (9-13%), firing shrinking (5.2-7.5%), water absorption (12.5-17.2%) and flexural strength (3.86-13.4 MPa). Noteworthy, an improvement in the properties (porosity, firing shrinking, water absorption, and flexural strength) of manufactured fired bricks was observed with the increase of firing temperature from 900 to 1100°C. All the measured properties complied with the construction norms and requirements. Moreover, regardless of the firing temperature, the environmental behavior of metals obeyed the requirements of the USEPA standards. Finally, fired bricks could be produced at high temperatures (1000°C) based on 100% of phosphate sludge without any substitution or addition of either chemical agents or binders. This sustainable brick-making process could be a promising approach for the Phosphate Company to partially manage these wastes, which are considered “non-profitable” for the moment and preserve soils that are exploited presently. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=phosphate%20treatment%20sludge" title="phosphate treatment sludge">phosphate treatment sludge</a>, <a href="https://publications.waset.org/abstracts/search?q=mine%20waste" title=" mine waste"> mine waste</a>, <a href="https://publications.waset.org/abstracts/search?q=backed%20bricks" title=" backed bricks"> backed bricks</a>, <a href="https://publications.waset.org/abstracts/search?q=waste%20valorization" title=" waste valorization"> waste valorization</a> </p> <a href="https://publications.waset.org/abstracts/141982/phosphate-tailings-in-view-of-a-better-waste-disposal-andor-valorization-case-of-tunisian-phosphates-mines" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141982.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">206</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Study of the Prevalence, Associated Factors and Impact of Maternal Perinatal Depression in Women Alexandria 2022</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nermeen%20Saad%20Elbeltagy">Nermeen Saad Elbeltagy</a>, <a href="https://publications.waset.org/abstracts/search?q=Hoda%20Ghareeb"> Hoda Ghareeb</a>, <a href="https://publications.waset.org/abstracts/search?q=Hesham%20Adel%20Elsheshtawy"> Hesham Adel Elsheshtawy</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadim%20Hamed"> Nadim Hamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Amany%20Ibrahim%20Mostafa"> Amany Ibrahim Mostafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Sara%20Hazem%20Hassan"> Sara Hazem Hassan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Depression is one of the most common mental health problems occurring in women during their child bearing years. Perinatal depression refers to major and minor depressive episodes that occur either during pregnancy or aer delivery. Although perinatal depression is common in developing countries, it is under-recognized in low and middle income countries making a substantial contribution to maternal and infant morbidity and mortality. About 12.5 - 42% of pregnant women and, 12 - 50% of post natal mothers in low and middle income countries such as Ethiopia had depression AIM OF THE WORK: To study prevalence, associated factors and impact of maternal perinatal depression in Alexandria. Patients and method: This study was conducted on 300 mothers at the postnatal ward in ElShatby Maternity Hospital from April 2022 unl October 2022. Females with past history of depression before pregnancy or females who receive medications inducing depression were excluded. The participants were asked to complete the questionnaire that includes the Edinburgh Postnatal Depression Scale (EPDS) as a screening test to obtain information concerning the current frame of mind at antepartum, partum and postpartum periods Results: The prevalence of perinatal depression was 22.3%. It was found that there is a significant negave moderate correlation between socioeconomic status and perinatal depression(r=-0.42). The present study revealed that about two thirds (60.7%) of postpartum women had low socioeconomic level. Also, less than one fourth (20%) of parents had high education and only one fourth (25.3%) of postpartum women were working. There was a statically significance difference between the number of previous abortions and perinatal depression (p=0.04). There was a significant moderate correlation between the amount of blood lost during delivery and an increased risk of developing postpartum depression. The prevalence of perinatal depression was high in cases of female neonates more than male ones. Conclusion: the prevalence of perinatal depression among the studied women was 22.3% of studied group. The significant factors identified in this study can be targeted to reduce the occurrence of perinatal depression among pregnant women in Alexandria through appropriate health interventions which includes perinatal depression screening, counseling, and the provision of support for pregnant women during antenatal care as well as lifestyle modification. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mental%20health" title="mental health">mental health</a>, <a href="https://publications.waset.org/abstracts/search?q=depression%20in%20pregnancy" title=" depression in pregnancy"> depression in pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=mental%20disorders" title=" mental disorders"> mental disorders</a>, <a href="https://publications.waset.org/abstracts/search?q=psychology%20in%20pregnancy" title=" psychology in pregnancy"> psychology in pregnancy</a> </p> <a href="https://publications.waset.org/abstracts/168477/study-of-the-prevalence-associated-factors-and-impact-of-maternal-perinatal-depression-in-women-alexandria-2022" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/168477.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">74</span> </span> </div> </div> <ul class="pagination"> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Mostafa%20Gamal&page=7" rel="prev">&lsaquo;</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Mostafa%20Gamal&page=1">1</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=Mostafa%20Gamal&page=2">2</a></li> <li class="page-item"><a class="page-link" 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