Fabrication Methodologies for Anti-Microbial Polypropylene Surfaces with Leachable and Non-leachable Anti-Microbial Agents

<!DOCTYPE html> <html lang="en" dir="ltr"> <head>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-P63WKM1TM1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-P63WKM1TM1'); </script>  <script type="text/javascript" > (function(m,e,t,r,i,k,a){m[i]=m[i]||function(){(m[i].a=m[i].a||[]).push(arguments)}; m[i].l=1*new Date(); for (var j = 0; j < document.scripts.length; j++) {if (document.scripts[j].src === r) { return; }} k=e.createElement(t),a=e.getElementsByTagName(t)[0],k.async=1,k.src=r,a.parentNode.insertBefore(k,a)}) (window, document, "script", "https://mc.yandex.ru/metrika/tag.js", "ym"); ym(55165297, "init", { clickmap:false, trackLinks:true, accurateTrackBounce:true, webvisor:false }); </script> <noscript><div><img src="https://mc.yandex.ru/watch/55165297" style="position:absolute; left:-9999px;" alt="" /></div></noscript>    <title>Fabrication Methodologies for Anti-Microbial Polypropylene Surfaces with Leachable and Non-leachable Anti-Microbial Agents</title> <meta name="description" content="Fabrication Methodologies for Anti-Microbial Polypropylene Surfaces with Leachable and Non-leachable Anti-Microbial Agents"> <meta name="keywords" content="anti-microbial activity, E. coli K-12 MG1655, copper (II) chloride dihydrate, magnesium hydroxide, leachable, non-leachable, compounding, thermal embossing"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div 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class="card"> <div class="card-body"><strong>Paper Count:</strong> 87407</div> </div> </div> </div> <div class="card publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Fabrication Methodologies for Anti-Microbial Polypropylene Surfaces with Leachable and Non-leachable Anti-Microbial Agents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saleh%20Alkarri">Saleh Alkarri</a>, <a href="https://publications.waset.org/abstracts/search?q=Dimple%20Sharma"> Dimple Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Teresa%20M.%20Bergholz"> Teresa M. Bergholz</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Rabnawaz"> Muhammad Rabnawaz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aims: Develop a methodology for the fabrication of anti-microbial polypropylene (PP) surfaces with (i) leachable copper, (II) chloride dihydrate (CuCl₂·₂H₂O) and (ii) non-leachable magnesium hydroxide (Mg(OH)₂) biocides. Methods and Results: Two methodologies are used to develop anti-microbial PP surfaces. One method involves melt-blending and subsequent injection molding, where the biocide additives were compounded with PP and subsequently injection-molded. The other method involves the thermal embossing of anti-microbial agents on the surface of a PP substrate. The obtained biocide-bearing PP surfaces were evaluated against E. coli K-12 MG1655 for 0, 4, and 24 h to evaluate their anti-microbial properties. The injection-molded PP bearing 5% CuCl2·₂H₂O showed a 6-log reduction of E. coli K-12 MG1655 after 24 h, while only 1 log reduction was observed for PP bearing 5% Mg(OH)2. The thermally embossed PP surfaces bearing CuCl2·2H2O and Mg(OH)₂ particles (at a concentration of 10 mg/mL) showed 3 log and 4 log reduction, respectively, against E.coli K-12 MG1655 after 24 h. Conclusion: The results clearly demonstrate that CuCl₂·2H₂O conferred anti-microbial properties to PP surfaces that were prepared by both injection molding as well as thermal embossing approaches owing to the presence of leachable copper ions. In contrast, the non-leachable Mg(OH)₂ imparted anti-microbial properties only to the surface prepared via the thermal embossing technique. Significance and Impact of The Study: Plastics with leachable biocides are effective anti-microbial surfaces, but their toxicity is a major concern. This study provides a fabrication methodology for non-leachable PP-based anti-microbial surfaces that are potentially safer. In addition, this strategy can be extended to many other plastics substrates. <iframe src="https://publications.waset.org/abstracts/165971.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anti-microbial%20activity" title="anti-microbial activity">anti-microbial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20coli%20K-12%20MG1655" title=" E. coli K-12 MG1655"> E. coli K-12 MG1655</a>, <a href="https://publications.waset.org/abstracts/search?q=copper%20%28II%29%20chloride%20dihydrate" title=" copper (II) chloride dihydrate"> copper (II) chloride dihydrate</a>, <a href="https://publications.waset.org/abstracts/search?q=magnesium%20hydroxide" title=" magnesium hydroxide"> magnesium hydroxide</a>, <a href="https://publications.waset.org/abstracts/search?q=leachable" title=" leachable"> leachable</a>, <a href="https://publications.waset.org/abstracts/search?q=non-leachable" title=" non-leachable"> non-leachable</a>, <a href="https://publications.waset.org/abstracts/search?q=compounding" title=" compounding"> compounding</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20embossing" title=" thermal embossing"> thermal embossing</a> </p> <a href="https://publications.waset.org/abstracts/165971/fabrication-methodologies-for-anti-microbial-polypropylene-surfaces-with-leachable-and-non-leachable-anti-microbial-agents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/165971.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">78</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> 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Fabrication Methodologies for Anti-Microbial Polypropylene Surfaces with Leachable and Non-leachable Anti-Microbial Agents