CINXE.COM

<!DOCTYPE html> <html lang="en" xmlns:fb="http://www.facebook.com/2008/fbml" class="wf-loading"> <head prefix="og: https://ogp.me/ns# fb: https://ogp.me/ns/fb# academia: https://ogp.me/ns/fb/academia#"> <meta charset="utf-8"> <meta name=viewport content="width=device-width, initial-scale=1"> <meta rel="search" type="application/opensearchdescription+xml" href="/open_search.xml" title="Academia.edu"> <title>Bruno Frea - Academia.edu</title>  <link href="//a.academia-assets.com/images/favicons/favicon-production.ico" rel="shortcut icon" type="image/vnd.microsoft.icon"> <link rel="apple-touch-icon" sizes="57x57" href="//a.academia-assets.com/images/favicons/apple-touch-icon-57x57.png"> <link rel="apple-touch-icon" sizes="60x60" href="//a.academia-assets.com/images/favicons/apple-touch-icon-60x60.png"> <link rel="apple-touch-icon" sizes="72x72" href="//a.academia-assets.com/images/favicons/apple-touch-icon-72x72.png"> <link rel="apple-touch-icon" sizes="76x76" href="//a.academia-assets.com/images/favicons/apple-touch-icon-76x76.png"> <link rel="apple-touch-icon" sizes="114x114" href="//a.academia-assets.com/images/favicons/apple-touch-icon-114x114.png"> <link rel="apple-touch-icon" sizes="120x120" href="//a.academia-assets.com/images/favicons/apple-touch-icon-120x120.png"> <link rel="apple-touch-icon" sizes="144x144" href="//a.academia-assets.com/images/favicons/apple-touch-icon-144x144.png"> <link rel="apple-touch-icon" sizes="152x152" href="//a.academia-assets.com/images/favicons/apple-touch-icon-152x152.png"> <link rel="apple-touch-icon" sizes="180x180" href="//a.academia-assets.com/images/favicons/apple-touch-icon-180x180.png"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-32x32.png" sizes="32x32"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-194x194.png" sizes="194x194"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-96x96.png" sizes="96x96"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/android-chrome-192x192.png" sizes="192x192"> <link rel="icon" type="image/png" href="//a.academia-assets.com/images/favicons/favicon-16x16.png" sizes="16x16"> <link rel="manifest" href="//a.academia-assets.com/images/favicons/manifest.json"> <meta name="msapplication-TileColor" content="#2b5797"> <meta name="msapplication-TileImage" content="//a.academia-assets.com/images/favicons/mstile-144x144.png"> <meta name="theme-color" content="#ffffff"> <script> window.performance && window.performance.measure && window.performance.measure("Time To First Byte", "requestStart", "responseStart"); </script> <script> (function() { if (!window.URLSearchParams || !window.history || !window.history.replaceState) { return; } var searchParams = new URLSearchParams(window.location.search); var paramsToDelete = [ 'fs', 'sm', 'swp', 'iid', 'nbs', 'rcc', // related content category 'rcpos', // related content carousel position 'rcpg', // related carousel page 'rchid', // related content hit id 'f_ri', // research interest id, for SEO tracking 'f_fri', // featured research interest, for SEO tracking (param key without value) 'f_rid', // from research interest directory for SEO tracking 'f_loswp', // from research interest pills on LOSWP sidebar for SEO tracking 'rhid', // referrring hit id ]; if (paramsToDelete.every((key) => searchParams.get(key) === null)) { return; } paramsToDelete.forEach((key) => { searchParams.delete(key); }); var cleanUrl = new URL(window.location.href); cleanUrl.search = searchParams.toString(); history.replaceState({}, document.title, cleanUrl); })(); </script> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "profiles/works", 'action': "summary", 'controller_action': 'profiles/works#summary', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script type="text/javascript"> window.sendUserTiming = function(timingName) { if (!(window.performance && window.performance.measure)) return; var entries = window.performance.getEntriesByName(timingName, "measure"); if (entries.length !== 1) return; var timingValue = Math.round(entries[0].duration); gtag('event', 'timing_complete', { name: timingName, value: timingValue, event_category: 'User-centric', }); }; window.sendUserTiming("Time To First Byte"); </script> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="ml32S6o2RHnzdEd9JjES9LQHTqW4z2SD9HsOH6yLzkRvq3THd6U79yqGJwAzSMvjWUWMLgLnBZYb7gg7oyY7uA" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/wow-3d36c19b4875b226bfed0fcba1dcea3f2fe61148383d97c0465c016b8c969290.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/social/home-79e78ce59bef0a338eb6540ec3d93b4a7952115b56c57f1760943128f4544d42.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/heading-95367dc03b794f6737f30123738a886cf53b7a65cdef98a922a98591d60063e3.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-bfbac2a470372e2f3a6661a65fa7ff0a0fbf7aa32534d9a831d683d2a6f9e01b.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/body-170d1319f0e354621e81ca17054bb147da2856ec0702fe440a99af314a6338c5.css" /><link crossorigin="" href="https://fonts.gstatic.com/" rel="preconnect" /><link href="https://fonts.googleapis.com/css2?family=DM+Sans:ital,opsz,wght@0,9..40,100..1000;1,9..40,100..1000&family=Gupter:wght@400;500;700&family=IBM+Plex+Mono:wght@300;400&family=Material+Symbols+Outlined:opsz,wght,FILL,GRAD@20,400,0,0&display=swap" rel="stylesheet" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/common-2b6f90dbd75f5941bc38f4ad716615f3ac449e7398313bb3bc225fba451cd9fa.css" /> <meta name="author" content="bruno frea" /> <meta name="description" content="Bruno Frea: 15 Followers, 3 Following, 148 Research papers. Research interests: Early Modern print culture, Jesuits, and Cervantes." /> <meta name="google-site-verification" content="bKJMBZA7E43xhDOopFZkssMMkBRjvYERV-NaN4R6mrs" /> <script> var $controller_name = 'works'; var $action_name = "summary"; var $rails_env = 'production'; var $app_rev = '8eceb4f58ee2b0718cf1b58485ccadc0eb8d7549'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.Aedu = { hit_data: null }; window.Aedu.SiteStats = {"premium_universities_count":14035,"monthly_visitors":"102 million","monthly_visitor_count":102411812,"monthly_visitor_count_in_millions":102,"user_count":283251997,"paper_count":55203019,"paper_count_in_millions":55,"page_count":432000000,"page_count_in_millions":432,"pdf_count":16500000,"pdf_count_in_millions":16}; window.Aedu.serverRenderTime = new Date(1740034574000); window.Aedu.timeDifference = new Date().getTime() - 1740034574000; window.Aedu.isUsingCssV1 = false; window.Aedu.enableLocalization = true; window.Aedu.activateFullstory = false; window.Aedu.serviceAvailability = { status: {"attention_db":"on","bibliography_db":"on","contacts_db":"on","email_db":"on","indexability_db":"on","mentions_db":"on","news_db":"on","notifications_db":"on","offsite_mentions_db":"on","redshift":"on","redshift_exports_db":"on","related_works_db":"on","ring_db":"on","user_tests_db":"on"}, serviceEnabled: function(service) { return this.status[service] === "on"; }, readEnabled: function(service) { return this.serviceEnabled(service) || this.status[service] === "read_only"; }, }; window.Aedu.viewApmTrace = function() { // Check if x-apm-trace-id meta tag is set, and open the trace in APM // in a new window if it is. var apmTraceId = document.head.querySelector('meta[name="x-apm-trace-id"]'); if (apmTraceId) { var traceId = apmTraceId.content; // Use trace ID to construct URL, an example URL looks like: // https://app.datadoghq.com/apm/traces?query=trace_id%31298410148923562634 var apmUrl = 'https://app.datadoghq.com/apm/traces?query=trace_id%3A' + traceId; window.open(apmUrl, '_blank'); } }; </script>  <link href="https://fonts.googleapis.com/css?family=Roboto:100,100i,300,300i,400,400i,500,500i,700,700i,900,900i" rel="stylesheet"> <link rel="preload" href="//maxcdn.bootstrapcdn.com/font-awesome/4.3.0/css/font-awesome.min.css" as="style" onload="this.rel='stylesheet'"> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/libraries-a9675dcb01ec4ef6aa807ba772c7a5a00c1820d3ff661c1038a20f80d06bb4e4.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/academia-40698df34f913bd208bb70f09d2feb7c6286046250be17a4db35bba2c08b0e2f.css" /> <link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system_legacy-056a9113b9a0f5343d013b29ee1929d5a18be35fdcdceb616600b4db8bd20054.css" /> <script src="//a.academia-assets.com/assets/webpack_bundles/runtime-bundle-005434038af4252ca37c527588411a3d6a0eabb5f727fac83f8bbe7fd88d93bb.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/webpack_libraries_and_infrequently_changed.wjs-bundle-a22f75d8519394c21253dae46c8c5d60ad36ea68c7d494347ec64229d8c1cf85.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/core_webpack.wjs-bundle-5708a105dd66b4c7d0ef30b7c094b1048423f0042bd2a7b123f2d99ee3cf46d9.js"></script> <script src="//a.academia-assets.com/assets/webpack_bundles/sentry.wjs-bundle-5fe03fddca915c8ba0f7edbe64c194308e8ce5abaed7bffe1255ff37549c4808.js"></script> <script> jade = window.jade || {}; jade.helpers = window.$h; jade._ = window._; </script>  <script id="tag-manager-head-root">(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer_old','GTM-5G9JF7Z');</script>  <script> window.gptadslots = []; window.googletag = window.googletag || {}; window.googletag.cmd = window.googletag.cmd || []; </script> <script type="text/javascript"> // TODO(jacob): This should be defined, may be rare load order problem. // Checking if null is just a quick fix, will default to en if unset. // Better fix is to run this immedietely after I18n is set. if (window.I18n != null) { I18n.defaultLocale = "en"; I18n.locale = "en"; I18n.fallbacks = true; } </script> <link rel="canonical" href="https://independent.academia.edu/BrunoFrea" /> </head>   <body class='c-profiles/works a-summary logged_out'>  <div id="fb-root"></div><script>window.fbAsyncInit = function() { FB.init({ appId: "2369844204", version: "v8.0", status: true, cookie: true, xfbml: true }); // Additional initialization code. if (window.InitFacebook) { // facebook.ts already loaded, set it up. window.InitFacebook(); } else { // Set a flag for facebook.ts to find when it loads. window.academiaAuthReadyFacebook = true; } };</script><script>window.fbAsyncLoad = function() { // Protection against double calling of this function if (window.FB) { return; } (function(d, s, id){ var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) {return;} js = d.createElement(s); js.id = id; js.src = "//connect.facebook.net/en_US/sdk.js"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk')); } if (!window.defer_facebook) { // Autoload if not deferred window.fbAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.fbAsyncLoad(); }, 5000); }</script> <div id="google-root"></div><script>window.loadGoogle = function() { if (window.InitGoogle) { // google.ts already loaded, set it up. window.InitGoogle("331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"); } else { // Set a flag for google.ts to use when it loads. window.GoogleClientID = "331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b"; } };</script><script>window.googleAsyncLoad = function() { // Protection against double calling of this function (function(d) { var js; var id = 'google-jssdk'; var ref = d.getElementsByTagName('script')[0]; if (d.getElementById(id)) { return; } js = d.createElement('script'); js.id = id; js.async = true; js.onload = loadGoogle; js.src = "https://accounts.google.com/gsi/client" ref.parentNode.insertBefore(js, ref); }(document)); } if (!window.defer_google) { // Autoload if not deferred window.googleAsyncLoad(); } else { // Defer loading by 5 seconds setTimeout(function() { window.googleAsyncLoad(); }, 5000); }</script> <div id="tag-manager-body-root">  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-5G9JF7Z" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>   <script> window.addEventListener('load', function() { if (document.querySelector('input[name="commit"]')) { document.querySelector('input[name="commit"]').addEventListener('click', function() { gtag('event', 'click', { event_category: 'button', event_label: 'Log In' }) }) } }); </script> </div> <script>var _comscore = _comscore || []; _comscore.push({ c1: "2", c2: "26766707" }); (function() { var s = document.createElement("script"), el = document.getElementsByTagName("script")[0]; s.async = true; s.src = (document.location.protocol == "https:" ? "https://sb" : "http://b") + ".scorecardresearch.com/beacon.js"; el.parentNode.insertBefore(s, el); })();</script><img src="https://sb.scorecardresearch.com/p?c1=2&c2=26766707&cv=2.0&cj=1" style="position: absolute; visibility: hidden" /> <div id='react-modal'></div> <div class='DesignSystem'> <a class='u-showOnFocus' href='#site'> Skip to main content </a> </div> <div id="upgrade_ie_banner" style="display: none;"><p>Academia.edu no longer supports Internet Explorer.</p><p>To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to <a href="https://www.academia.edu/upgrade-browser">upgrade your browser</a>.</p></div><script>// Show this banner for all versions of IE if (!!window.MSInputMethodContext || /(MSIE)/.test(navigator.userAgent)) { document.getElementById('upgrade_ie_banner').style.display = 'block'; }</script> <div class="DesignSystem bootstrap ShrinkableNav"><div class="navbar navbar-default main-header"><div class="container-wrapper" id="main-header-container"><div class="container"><div class="navbar-header"><div class="nav-left-wrapper u-mt0x"><div class="nav-logo"><a data-main-header-link-target="logo_home" href="https://www.academia.edu/"><img class="visible-xs-inline-block" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015-A.svg" width="24" height="24" /><img width="145.2" height="18" class="hidden-xs" style="height: 24px;" alt="Academia.edu" src="//a.academia-assets.com/images/academia-logo-redesign-2015.svg" /></a></div><div class="nav-search"><div class="SiteSearch-wrapper select2-no-default-pills"><form class="js-SiteSearch-form DesignSystem" action="https://www.academia.edu/search" accept-charset="UTF-8" method="get"><i class="SiteSearch-icon fa fa-search u-fw700 u-positionAbsolute u-tcGrayDark"></i><input class="js-SiteSearch-form-input SiteSearch-form-input form-control" data-main-header-click-target="search_input" name="q" placeholder="Search" type="text" value="" /></form></div></div></div><div class="nav-right-wrapper pull-right"><ul class="NavLinks js-main-nav list-unstyled"><li class="NavLinks-link"><a class="js-header-login-url Button Button--inverseGray Button--sm u-mb4x" id="nav_log_in" rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="NavLinks-link u-p0x"><a class="Button Button--inverseGray Button--sm u-mb4x" rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li></ul><button class="hidden-lg hidden-md hidden-sm u-ml4x navbar-toggle collapsed" data-target=".js-mobile-header-links" data-toggle="collapse" type="button"><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span></button></div></div><div class="collapse navbar-collapse js-mobile-header-links"><ul class="nav navbar-nav"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/login">Log In</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/signup">Sign Up</a></li><li class="u-borderColorGrayLight u-borderBottom1 js-mobile-nav-expand-trigger"><a href="#">more&nbsp<span class="caret"></span></a></li><li><ul class="js-mobile-nav-expand-section nav navbar-nav u-m0x collapse"><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/about">About</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/press">Press</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="false" href="https://www.academia.edu/documents">Papers</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://www.academia.edu/hiring"><i class="fa fa-briefcase"></i> We're Hiring!</a></li><li class="u-borderColorGrayLight u-borderBottom1"><a rel="nofollow" href="https://support.academia.edu/hc/en-us"><i class="fa fa-question-circle"></i> Help Center</a></li><li class="js-mobile-nav-collapse-trigger u-borderColorGrayLight u-borderBottom1 dropup" style="display:none"><a href="#">less&nbsp<span class="caret"></span></a></li></ul></li></ul></div></div></div><script>(function(){ var $moreLink = $(".js-mobile-nav-expand-trigger"); var $lessLink = $(".js-mobile-nav-collapse-trigger"); var $section = $('.js-mobile-nav-expand-section'); $moreLink.click(function(ev){ ev.preventDefault(); $moreLink.hide(); $lessLink.show(); $section.collapse('show'); }); $lessLink.click(function(ev){ ev.preventDefault(); $moreLink.show(); $lessLink.hide(); $section.collapse('hide'); }); })() if ($a.is_logged_in() || false) { new Aedu.NavigationController({ el: '.js-main-nav', showHighlightedNotification: false }); } else { $(".js-header-login-url").attr("href", $a.loginUrlWithRedirect()); } Aedu.autocompleteSearch = new AutocompleteSearch({el: '.js-SiteSearch-form'});</script></div></div> <div id='site' class='fixed'> <div id="content" class="clearfix"> <script>document.addEventListener('DOMContentLoaded', function(){ var $dismissible = $(".dismissible_banner"); $dismissible.click(function(ev) { $dismissible.hide(); }); });</script> <script src="//a.academia-assets.com/assets/webpack_bundles/profile.wjs-bundle-e82262883b6d356891320893468fcd8e98331fb3946e6cee6385e2eadb9c95b2.js" defer="defer"></script><script>$viewedUser = Aedu.User.set_viewed( {"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea","photo":"/images/s65_no_pic.png","has_photo":false,"is_analytics_public":false,"interests":[{"id":43242,"name":"Early Modern print culture","url":"https://www.academia.edu/Documents/in/Early_Modern_print_culture"},{"id":60543,"name":"Jesuits","url":"https://www.academia.edu/Documents/in/Jesuits"},{"id":28602,"name":"Cervantes","url":"https://www.academia.edu/Documents/in/Cervantes"},{"id":21544,"name":"Medieval Italian Literature","url":"https://www.academia.edu/Documents/in/Medieval_Italian_Literature"},{"id":19455,"name":"Early Modern economic and social history","url":"https://www.academia.edu/Documents/in/Early_Modern_economic_and_social_history"}]} ); if ($a.is_logged_in() && $viewedUser.is_current_user()) { $('body').addClass('profile-viewed-by-owner'); } $socialProfiles = []</script><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://independent.academia.edu/BrunoFrea","location":"/BrunoFrea","scheme":"https","host":"independent.academia.edu","port":null,"pathname":"/BrunoFrea","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="ProfileCheckPaperUpdate" data-props="{}" data-trace="false" data-dom-id="ProfileCheckPaperUpdate-react-component-87207e97-8ab1-4122-bc5a-81f9d2d413d2"></div> <div id="ProfileCheckPaperUpdate-react-component-87207e97-8ab1-4122-bc5a-81f9d2d413d2"></div> <div class="DesignSystem"><div class="onsite-ping" id="onsite-ping"></div></div><div class="profile-user-info DesignSystem"><div class="social-profile-container"><div class="left-panel-container"><div class="user-info-component-wrapper"><div class="user-summary-cta-container"><div class="user-summary-container"><div class="social-profile-avatar-container"><img class="profile-avatar u-positionAbsolute" border="0" alt="" src="//a.academia-assets.com/images/s200_no_pic.png" /></div><div class="title-container"><h1 class="ds2-5-heading-sans-serif-sm">Bruno Frea</h1><div class="affiliations-container fake-truncate js-profile-affiliations"></div></div></div><div class="sidebar-cta-container"><button class="ds2-5-button hidden profile-cta-button grow js-profile-follow-button" data-broccoli-component="user-info.follow-button" data-click-track="profile-user-info-follow-button" data-follow-user-fname="Bruno" data-follow-user-id="64819573" data-follow-user-source="profile_button" data-has-google="false"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">add</span>Follow</button><button class="ds2-5-button hidden profile-cta-button grow js-profile-unfollow-button" data-broccoli-component="user-info.unfollow-button" data-click-track="profile-user-info-unfollow-button" data-unfollow-user-id="64819573"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">done</span>Following</button></div></div><div class="user-stats-container"><a><div class="stat-container js-profile-followers"><p class="label">Followers</p><p class="data">15</p></div></a><a><div class="stat-container js-profile-followees" data-broccoli-component="user-info.followees-count" data-click-track="profile-expand-user-info-following"><p class="label">Following</p><p class="data">3</p></div></a><a><div class="stat-container js-profile-coauthors" data-broccoli-component="user-info.coauthors-count" data-click-track="profile-expand-user-info-coauthors"><p class="label">Co-authors</p><p class="data">3</p></div></a><div class="js-mentions-count-container" style="display: none;"><a href="/BrunoFrea/mentions"><div class="stat-container"><p class="label">Mentions</p><p class="data"></p></div></a></div><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="suggested-academics-container"><div class="suggested-academics--header"><p class="ds2-5-body-md-bold">Related Authors</p></div><ul class="suggested-user-card-list"><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://oxford.academia.edu/SheilaghOgilvie"><img class="profile-avatar u-positionAbsolute" alt="Sheilagh Ogilvie" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/5770/2229/2258/s200_sheilagh.ogilvie.jpeg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://oxford.academia.edu/SheilaghOgilvie">Sheilagh Ogilvie</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">University of Oxford</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://utoronto.academia.edu/ElisaBrilli"><img class="profile-avatar u-positionAbsolute" alt="Elisa Brilli" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/5838/2033215/43741422/s200_elisa.brilli.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://utoronto.academia.edu/ElisaBrilli">Elisa Brilli</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">University of Toronto</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://wayne.academia.edu/ThiagoKrause"><img class="profile-avatar u-positionAbsolute" alt="Thiago Krause" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/187494/3304854/19455706/s200_thiago.krause.jpeg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://wayne.academia.edu/ThiagoKrause">Thiago Krause</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Wayne State University</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://univie.academia.edu/KatalinPrajda"><img class="profile-avatar u-positionAbsolute" alt="Kati (Katalin) Prajda" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/284975/58171/140089718/s200_katalin.prajda.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://univie.academia.edu/KatalinPrajda">Kati (Katalin) Prajda</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">University of Vienna</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://fbk.academia.edu/MassimoRospocher"><img class="profile-avatar u-positionAbsolute" alt="Massimo Rospocher" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/302170/62097/4188269/s200_massimo.rospocher.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://fbk.academia.edu/MassimoRospocher">Massimo Rospocher</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Bruno Kessler Foundation</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://usp-br.academia.edu/Thom%C3%A1sHaddad"><img class="profile-avatar u-positionAbsolute" alt="Thomás A S Haddad" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/542672/195162/10961285/s200_thom_s.haddad.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://usp-br.academia.edu/Thom%C3%A1sHaddad">Thomás A S Haddad</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Universidade de São Paulo</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://unive.academia.edu/Adri%C3%A1nJS%C3%A1ez"><img class="profile-avatar u-positionAbsolute" alt="Adrián J. Sáez" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/741191/252825/49344268/s200_adri_n_j..s_ez.jpeg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://unive.academia.edu/Adri%C3%A1nJS%C3%A1ez">Adrián J. Sáez</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Università Ca' Foscari Venezia</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://uco-es.academia.edu/EnriqueSoriaMesa"><img class="profile-avatar u-positionAbsolute" alt="Enrique Soria Mesa" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/1201530/431987/534789/s200_enrique.soria_mesa.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://uco-es.academia.edu/EnriqueSoriaMesa">Enrique Soria Mesa</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Universidad de Córdoba</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://unex.academia.edu/AMPAROL%C3%93PEZARANDIA"><img class="profile-avatar u-positionAbsolute" alt="María Amparo López Arandia" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/1248969/456164/14171154/s200_mar_a_amparo.l_pez_arandia.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://unex.academia.edu/AMPAROL%C3%93PEZARANDIA">María Amparo López Arandia</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">Universidad de Extremadura</p></div></div><div class="suggested-user-card"><div class="suggested-user-card__avatar social-profile-avatar-container"><a href="https://ucc-ie.academia.edu/BrendanDooley"><img class="profile-avatar u-positionAbsolute" alt="Brendan Dooley" border="0" onerror="if (this.src != '//a.academia-assets.com/images/s200_no_pic.png') this.src = '//a.academia-assets.com/images/s200_no_pic.png';" width="200" height="200" src="https://0.academia-photos.com/1307480/511362/642352/s200_brendan.dooley.jpg" /></a></div><div class="suggested-user-card__user-info"><a class="suggested-user-card__user-info__header ds2-5-body-sm-bold ds2-5-body-link" href="https://ucc-ie.academia.edu/BrendanDooley">Brendan Dooley</a><p class="suggested-user-card__user-info__subheader ds2-5-body-xs">University College Cork</p></div></div></ul></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="64819573" href="https://www.academia.edu/Documents/in/Early_Modern_print_culture"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://independent.academia.edu/BrunoFrea","location":"/BrunoFrea","scheme":"https","host":"independent.academia.edu","port":null,"pathname":"/BrunoFrea","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Early Modern print culture"]}" data-trace="false" data-dom-id="Pill-react-component-0b671a81-651b-44ed-8a00-5642b7b7c6cb"></div> <div id="Pill-react-component-0b671a81-651b-44ed-8a00-5642b7b7c6cb"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="64819573" href="https://www.academia.edu/Documents/in/Jesuits"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Jesuits"]}" data-trace="false" data-dom-id="Pill-react-component-1abfa0e3-cc7a-4bd7-852b-268d653cc6ad"></div> <div id="Pill-react-component-1abfa0e3-cc7a-4bd7-852b-268d653cc6ad"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="64819573" href="https://www.academia.edu/Documents/in/Cervantes"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Cervantes"]}" data-trace="false" data-dom-id="Pill-react-component-96139f89-232b-4e8e-afc3-6872795befdd"></div> <div id="Pill-react-component-96139f89-232b-4e8e-afc3-6872795befdd"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="64819573" href="https://www.academia.edu/Documents/in/Medieval_Italian_Literature"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Medieval Italian Literature"]}" data-trace="false" data-dom-id="Pill-react-component-e4ebee8b-5674-496b-a725-dad0efc70b5f"></div> <div id="Pill-react-component-e4ebee8b-5674-496b-a725-dad0efc70b5f"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="64819573" href="https://www.academia.edu/Documents/in/Early_Modern_economic_and_social_history"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Early Modern economic and social history"]}" data-trace="false" data-dom-id="Pill-react-component-2d7e93b0-a1d3-400a-a1b8-1778e4b77917"></div> <div id="Pill-react-component-2d7e93b0-a1d3-400a-a1b8-1778e4b77917"></div> </a></div></div></div></div><div class="right-panel-container"><div class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Bruno Frea</h3></div><div class="js-work-strip profile--work_container" data-work-id="33219340"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219340/Beta_2_glycoprotein_1_and_alpha_1_antitrypsin_as_urinary_markers_of_renal_cancer_in_von_Hippel_Lindau_patients"><img alt="Research paper thumbnail of Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel–Lindau patients" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219340/Beta_2_glycoprotein_1_and_alpha_1_antitrypsin_as_urinary_markers_of_renal_cancer_in_von_Hippel_Lindau_patients">Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel–Lindau patients</a></div><div class="wp-workCard_item"><span>Biomarkers</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Von Hippel-Lindau disease (VHLD) is a rare inherited neoplastic syndrome. Among all the VHLD-asso...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Von Hippel-Lindau disease (VHLD) is a rare inherited neoplastic syndrome. Among all the VHLD-associated tumors, clear cell renal cell carcinoma (ccRCC) is the major cause of death. The aim of this paper is the discovery of new non-invasive biomarker for the monitoring of VHLD patients. We compared the urinary proteome of VHLD patients, ccRCC patients and healthy volunteers. Among all differentially expressed proteins, alpha-1-antitrypsin (A1AT) and APOH (beta-2-glycoprotein-1) are strongly over-abundant only in the urine of VHLD patients with a history of ccRCC. A1AT and APOH could be promising non-invasive biomarkers.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219340"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219340"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219340; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219340]").text(description); $(".js-view-count[data-work-id=33219340]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219340; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219340']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219340]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219340,"title":"Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel–Lindau patients","internal_url":"https://www.academia.edu/33219340/Beta_2_glycoprotein_1_and_alpha_1_antitrypsin_as_urinary_markers_of_renal_cancer_in_von_Hippel_Lindau_patients","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219339"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219339/1012_Sentinel_Lymph_Node_Surgery_in_Prostate_Cancer_Results_of_a_Prospective_Study_with_a_10_Years_Follow_Up"><img alt="Research paper thumbnail of 1012 Sentinel Lymph Node Surgery in Prostate Cancer: Results of a Prospective Study with a 10 Years Follow Up" class="work-thumbnail" src="https://attachments.academia-assets.com/53296898/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219339/1012_Sentinel_Lymph_Node_Surgery_in_Prostate_Cancer_Results_of_a_Prospective_Study_with_a_10_Years_Follow_Up">1012 Sentinel Lymph Node Surgery in Prostate Cancer: Results of a Prospective Study with a 10 Years Follow Up</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c584585d377791971f58f6368dd4c9fe" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296898,"asset_id":33219339,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296898/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219339"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219339"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219339; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219339]").text(description); $(".js-view-count[data-work-id=33219339]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219339; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219339']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c584585d377791971f58f6368dd4c9fe" } } $('.js-work-strip[data-work-id=33219339]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219339,"title":"1012 Sentinel Lymph Node Surgery in Prostate Cancer: Results of a Prospective Study with a 10 Years Follow Up","internal_url":"https://www.academia.edu/33219339/1012_Sentinel_Lymph_Node_Surgery_in_Prostate_Cancer_Results_of_a_Prospective_Study_with_a_10_Years_Follow_Up","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296898,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296898/thumbnails/1.jpg","file_name":"s1569-9056_2810_2960991-820170527-12659-tkejl8.pdf","download_url":"https://www.academia.edu/attachments/53296898/download_file","bulk_download_file_name":"1012_Sentinel_Lymph_Node_Surgery_in_Pros.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296898/s1569-9056_2810_2960991-820170527-12659-tkejl8-libre.pdf?1495898476=\u0026response-content-disposition=attachment%3B+filename%3D1012_Sentinel_Lymph_Node_Surgery_in_Pros.pdf\u0026Expires=1740038174\u0026Signature=aH~5ectJkIgUEkOzIi3mMPlTvgnUcwqcvPfSIUVWfrT3ads1FoYK962vfLdMdTsUHO2gFMYHWi2TNTeVbfqYPdVgrwwKNsqK8vT-c~mbH58iYvd~pp6FeBF9RPdy2jhxvZj62HtfpGlcRon2um5u1rhB5WrKo0nNTbVB5lpBuBAeL8QqVs-HabwpwatMBkZgVb9gqRFIxQAhEsUV9ENXt0pgAL0rj9iABjjuNGnGZiIRhaBOLrYZcmdeTpvUTlbT-Jh7OCle2uZf1A828gfC0hLTC5-LtcP8haGJNbu8ker64IrOOG0cVSUmychJ5AiLpJIT2hobX6P2CokekrfRuA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219338"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219338/Morphological_and_Functional_Anatomy_of_Male_Pelvis"><img alt="Research paper thumbnail of Morphological and Functional Anatomy of Male Pelvis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219338/Morphological_and_Functional_Anatomy_of_Male_Pelvis">Morphological and Functional Anatomy of Male Pelvis</a></div><div class="wp-workCard_item"><span>Male Stress Urinary Incontinence</span><span>, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219338"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219338"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219338; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219338]").text(description); $(".js-view-count[data-work-id=33219338]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219338; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219338']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219338]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219338,"title":"Morphological and Functional Anatomy of Male Pelvis","internal_url":"https://www.academia.edu/33219338/Morphological_and_Functional_Anatomy_of_Male_Pelvis","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219337"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219337/Evaluation_of_the_efficacy_and_patient_compliance_to_different_treatment_modalities_for_erectile_dysfunction_after_nonnerve_sparing_radical_retropubic_prostatectomy_NNSRRP_"><img alt="Research paper thumbnail of Evaluation of the efficacy and patient compliance to different treatment modalities for erectile dysfunction after nonnerve sparing radical retropubic prostatectomy (NNSRRP)" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219337/Evaluation_of_the_efficacy_and_patient_compliance_to_different_treatment_modalities_for_erectile_dysfunction_after_nonnerve_sparing_radical_retropubic_prostatectomy_NNSRRP_">Evaluation of the efficacy and patient compliance to different treatment modalities for erectile dysfunction after nonnerve sparing radical retropubic prostatectomy (NNSRRP)</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219337"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219337"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219337; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219337]").text(description); $(".js-view-count[data-work-id=33219337]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219337; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219337']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219337]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219337,"title":"Evaluation of the efficacy and patient compliance to different treatment modalities for erectile dysfunction after nonnerve sparing radical retropubic prostatectomy (NNSRRP)","internal_url":"https://www.academia.edu/33219337/Evaluation_of_the_efficacy_and_patient_compliance_to_different_treatment_modalities_for_erectile_dysfunction_after_nonnerve_sparing_radical_retropubic_prostatectomy_NNSRRP_","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219336"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219336/759_Does_saline_hypertonic_solution_reduce_the_risk_of_Turp_syndrome"><img alt="Research paper thumbnail of 759 Does saline hypertonic solution reduce the risk of Turp syndrome?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219336/759_Does_saline_hypertonic_solution_reduce_the_risk_of_Turp_syndrome">759 Does saline hypertonic solution reduce the risk of Turp syndrome?</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2004</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219336"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219336"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219336; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219336]").text(description); $(".js-view-count[data-work-id=33219336]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219336; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219336']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219336]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219336,"title":"759 Does saline hypertonic solution reduce the risk of Turp syndrome?","internal_url":"https://www.academia.edu/33219336/759_Does_saline_hypertonic_solution_reduce_the_risk_of_Turp_syndrome","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219335"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219335/Cavernous_hemangioma_of_the_spongious_body_of_the_urethra_a_case_report"><img alt="Research paper thumbnail of Cavernous hemangioma of the spongious body of the urethra: a case report" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219335/Cavernous_hemangioma_of_the_spongious_body_of_the_urethra_a_case_report">Cavernous hemangioma of the spongious body of the urethra: a case report</a></div><div class="wp-workCard_item"><span>Rivista Urologia</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Urethral hemangiomas are rare and benign tumors, probably originating from a unipotent angioblast...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Urethral hemangiomas are rare and benign tumors, probably originating from a unipotent angioblastic stem cell. They can vary in size and the clinical appearance can range from asymptomatic lesions to urethral bleeding or gross hematuria. We present the case of an 18-year-old male, with a history of urethral bleeding. Cystourethoscopy revealed a solitary bulging mass into the lumen, about 6 cm far from the external meatus. Doppler study confirmed that the lesion was in communication with the vessels of the left spongious body. The patient underwent surgical removal of the lesion. The post-procedure Doppler study revealed an inflammation-based remodeling of the spongoius urethra and the absence of the previous vascular connection. At the time of publication the patient is still symptom-free. The surgical removal of urethral hemangiomas is by far the technique of choice for treating such lesions in young patients, thus avoiding side effects of LASER treatments.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219335"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219335"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219335; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219335]").text(description); $(".js-view-count[data-work-id=33219335]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219335; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219335']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219335]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219335,"title":"Cavernous hemangioma of the spongious body of the urethra: a case report","internal_url":"https://www.academia.edu/33219335/Cavernous_hemangioma_of_the_spongious_body_of_the_urethra_a_case_report","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219334"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219334/Prostate_biopsy_after_abdominoperineal_resection_a_diagnostic_challenge"><img alt="Research paper thumbnail of Prostate biopsy after abdominoperineal resection: a diagnostic challenge" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219334/Prostate_biopsy_after_abdominoperineal_resection_a_diagnostic_challenge">Prostate biopsy after abdominoperineal resection: a diagnostic challenge</a></div><div class="wp-workCard_item"><span>Rivista Urologia</span><span>, 2013</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Prostate biopsy in patients who underwent abdominoperineal resection (APR) of the rectum is commo...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Prostate biopsy in patients who underwent abdominoperineal resection (APR) of the rectum is commonly considered a technical challenge even for experienced urologists, although tissue diagnosis is essential in prostate cancer management. Transperitoneal, transperineal and transgluteal approaches have been reported, under US, CT or MRI guidance. Transperineal biopsy seems to be the safest and most cost-effective technique. At our institution we developed a modified transperineal biopsy approach with combined transperineal and suprapubic US guidance. Here we report the cases of two patients who came to our institution for PSA raise years after APR procedure, describing in detail the modified transperineal technique and the results of tissue sampling.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219334"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219334"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219334; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219334]").text(description); $(".js-view-count[data-work-id=33219334]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219334; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219334']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219334]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219334,"title":"Prostate biopsy after abdominoperineal resection: a diagnostic challenge","internal_url":"https://www.academia.edu/33219334/Prostate_biopsy_after_abdominoperineal_resection_a_diagnostic_challenge","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219333"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219333/99_How_much_intuitive_is_the_da_Vinci_system_Validation_of_the_Intuitive_Surgical_System_training_practicum"><img alt="Research paper thumbnail of 99 How much intuitive is the da Vinci system? Validation of the Intuitive Surgical System training practicum" class="work-thumbnail" src="https://attachments.academia-assets.com/53296896/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219333/99_How_much_intuitive_is_the_da_Vinci_system_Validation_of_the_Intuitive_Surgical_System_training_practicum">99 How much intuitive is the da Vinci system? Validation of the Intuitive Surgical System training practicum</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The revolutionary technology of robotics has given the opportunity to experienced open surgeons a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The revolutionary technology of robotics has given the opportunity to experienced open surgeons around the world to adapt to a new setting of minimal invasive surgery. Although the learning curve is not steep, it can by itself, hinder many of the advantages of a minimally invasive procedure. The purpose of the present study is to compare the systemic response of the well established minilaparotomy radical retropubic prostatectomy (RRP) with the robotic assisted radical prostatectomy (RALP) accomplished by a beginner console surgeon, by measuring the level of serum inflammatory cytokines (IL-1a, IL-6, IL-10, TNF-a, CRP). Materials and Methods: After obtaining approval from the ethical committee of the two institutions, a prospective nonrandomized study was conducted. From May 2008 to February 2009, 60 patients with clinically organ confined prostate cancer (cT1-2) that had been confirmed histologically, were included. Thirty consecutive patients (group A) underwent RRP from a single experienced surgeon in one institution, while RALP was offered in 30 consecutive patients (group B) in another institution by a single surgeon. Exclusion criteria were equal in both groups and no significant differences were observed in the preoperative variables. Blood samples were collected 24 h (T0) preoperatively and at 9h (T1), 24h (T2) and 48h (T3) postoperatively. HCt, Hgb, WBC were measured and IL-1a, IL-6, IL-10, TNF-a, CRP were assayed by ELISA. Independent sample t-test was used to calculate the statistical significance of differences. A p-value of less than 0.05 was considered statistically significant. Results: The two groups were comparable for age, BMI, preoperative PSA, specimen weight and volume. CRP (mg/L) was significantly elevated in group A, at T1 (mean 7.04 vs 4.65, P = 0.043), T2 (mean 12.00 vs 9.53, P = 0.001) and T3 (mean 18.92 vs 14.98, P = 0.003). IL-6 (Pg/mL) was also elevated in group A, at T1 (mean 40.63 vs 19.79, P = 0.001) and T2 (mean 34.86 vs 15.34, P = 0.001). Hct (%) was reduced in group A, at T3 (mean 34.53 vs 36.57, P = 0.033). Hgb (gr/dL) was also reduced in group A, at T2 (mean 11.14 vs 11.97, P = 0.01) and at T3 (mean 10.68 vs 12.35, P < 0.001). WBC was elevated in group A, at T1 (mean 12.90 vs 9.36, P < 0.001), T2 (mean 11.93 vs 8.73, P = 0.001), and at T3 (mean 9.90 vs 7.84, P = 0.012). Group A required transfusion with a mean of 2.2 (±0.64) PRBC, while no PRBC were provided in the RALP group. Operating time was significantly higher in the RALP group (mean 130.50 vs 252.50, P < 0.001).</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="77bbceafb3e19e9a6fd40f93800cea7c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296896,"asset_id":33219333,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296896/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219333"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219333"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219333; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219333]").text(description); $(".js-view-count[data-work-id=33219333]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219333; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219333']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "77bbceafb3e19e9a6fd40f93800cea7c" } } $('.js-work-strip[data-work-id=33219333]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219333,"title":"99 How much intuitive is the da Vinci system? Validation of the Intuitive Surgical System training practicum","internal_url":"https://www.academia.edu/33219333/99_How_much_intuitive_is_the_da_Vinci_system_Validation_of_the_Intuitive_Surgical_System_training_practicum","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296896,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296896/thumbnails/1.jpg","file_name":"s1569-9056_2811_2961427-920170527-12659-18j9lnm.pdf","download_url":"https://www.academia.edu/attachments/53296896/download_file","bulk_download_file_name":"99_How_much_intuitive_is_the_da_Vinci_sy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296896/s1569-9056_2811_2961427-920170527-12659-18j9lnm-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3D99_How_much_intuitive_is_the_da_Vinci_sy.pdf\u0026Expires=1740038174\u0026Signature=Rtz4xoyx1k~wmPr54Z-aYF5UFOgD21yZuU1V2fHthatFnKSlUkft~twCvb8KcC5HX0uFfm9MnxKbrBxUCU4RzldBA5hFUde63DKd59f~Je5WsxQ8yMHvbxF1BGOPQqhYnR45FHzQOMn-ILPZT0Ux86vEw0D7J6BywQXmvTs53IaTA0ioiqIWxU9G3lLRTAvujkZS~giocP6-RFPhnNiYmiHGT39LrmcvrBR2fbS-XxBxmluhxI7rjGs~5u7m3d0FDPKe1fpHBLvE-PnMiww-Dtzqeq9oK3mhLQcyf7GRIddNK1K3YoZpVAofp138c69A6hxMQdINeeV8Yx2yPEe5LA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219332"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219332/1351_Post_Prostatectomy_Urethral_Hypermobility_Mith_or_Real"><img alt="Research paper thumbnail of 1351 Post Prostatectomy Urethral Hypermobility : Mith or Real?" class="work-thumbnail" src="https://attachments.academia-assets.com/53296895/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219332/1351_Post_Prostatectomy_Urethral_Hypermobility_Mith_or_Real">1351 Post Prostatectomy Urethral Hypermobility : Mith or Real?</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">INTRODUCTION AND OBJECTIVES: Bladder puncture with a trocar is a common intraoperative complicati...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">INTRODUCTION AND OBJECTIVES: Bladder puncture with a trocar is a common intraoperative complication during retropubic midurethral sling (MUS) surgery and is typically treated with trocar repositioning and bladder drainage. However, there is little information regarding the impact of bladder puncture on short-and long-term bladder storage and emptying.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c060c5fcf49dd59a95d6995e9b29b925" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296895,"asset_id":33219332,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296895/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219332"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219332"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219332; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219332]").text(description); $(".js-view-count[data-work-id=33219332]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219332; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219332']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c060c5fcf49dd59a95d6995e9b29b925" } } $('.js-work-strip[data-work-id=33219332]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219332,"title":"1351 Post Prostatectomy Urethral Hypermobility : Mith or Real?","internal_url":"https://www.academia.edu/33219332/1351_Post_Prostatectomy_Urethral_Hypermobility_Mith_or_Real","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296895,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296895/thumbnails/1.jpg","file_name":"j.juro.2012.02.173420170527-12659-1at38ap.pdf","download_url":"https://www.academia.edu/attachments/53296895/download_file","bulk_download_file_name":"1351_Post_Prostatectomy_Urethral_Hypermo.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296895/j.juro.2012.02.173420170527-12659-1at38ap-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3D1351_Post_Prostatectomy_Urethral_Hypermo.pdf\u0026Expires=1740038174\u0026Signature=c8~zE8xAUZFi2D7k5NXHy-~yFQpv9wy1Sj9pMYfbe4a7qRq-rneUdVCge463vuqCszrHp7INzHACVjO0LWxFDCCVaeGaFTasdLoAHxaFpFPCXUZGYiUfXQnlX6PhdqKxTzxnzb3vyMr~sBAFJCHtmCata~S35wk5BtT8zENuA1zZO~Nm7shloGxaJmCOz9QaPfnKe14FXgMxDzX6Yqce2foj6DmwUdy8wUwjpS4vGIEXLzz1ejUd6CeGR6ZXnnVi4TEEpFyMro8ifRHDn3lt~PSkGub672WSsJhnYF76PQM4pNMCmCdzTePF-QJwW58Kc6oCQeKE9Ce6rzcgPi6rIQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219331"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219331/Proposal_of_an_Improved_Prognostic_Classification_for_pT3_Renal_Cell_Carcinoma"><img alt="Research paper thumbnail of Proposal of an Improved Prognostic Classification for pT3 Renal Cell Carcinoma" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219331/Proposal_of_an_Improved_Prognostic_Classification_for_pT3_Renal_Cell_Carcinoma">Proposal of an Improved Prognostic Classification for pT3 Renal Cell Carcinoma</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The prognostic accuracy of the current TNM 2002 staging system for locally advanced renal cell ca...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The prognostic accuracy of the current TNM 2002 staging system for locally advanced renal cell carcinoma has been questioned. To contribute to the development of a more accurate classification for this stage of disease we assessed the correlation between patterns of invasion in the pT3 category and outcomes in a large multi-institutional series. Pathological data and clinical followup on 513 pT3 renal cell carcinoma cases treated with radical nephrectomy between 1983 and 2005 at 3 Italian academic centers were retrospectively reviewed. Cause specific survival rates were calculated with the Kaplan-Meier method and multivariate analysis was performed using the Cox proportional hazards regression model. Estimated overall 5-year cause specific survival was 50.1% at a median followup of 61.5 months in survivors. The current TNM classification was not a significant outcome prognosticator. Patients with a tumor invading only the perirenal or sinus fat were at lowest risk for death from the disease. Patients at intermediate risk had tumors with invasion of the venous system alone. Simultaneous perirenal fat and sinus fat invasion or perirenal fat and vascular invasion as well as adrenal gland involvement characterized high risk tumors. Low risk tumors could be further divided into 2 groups with different outcomes based on a size cutoff of 7 cm. Our classification was a significant predictor of survival on multivariate analysis as well as M stage, N stage, Fuhrman grade and tumor size. We confirm that the prognostic usefulness of the current 2002 TNM system for pT3 renal cell carcinoma is limited. We have identified 4 groups of tumors with distinct patterns of invasion and significantly different survival probabilities in this category. Large prospective series are needed to validate these findings.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219331"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219331"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219331; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219331]").text(description); $(".js-view-count[data-work-id=33219331]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219331; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219331']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219331]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219331,"title":"Proposal of an Improved Prognostic Classification for pT3 Renal Cell Carcinoma","internal_url":"https://www.academia.edu/33219331/Proposal_of_an_Improved_Prognostic_Classification_for_pT3_Renal_Cell_Carcinoma","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219330"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219330/Y_Neobladder_An_Easy_Fast_and_Reliable_Procedure"><img alt="Research paper thumbnail of Y-Neobladder: An Easy, Fast, and Reliable Procedure" class="work-thumbnail" src="https://attachments.academia-assets.com/53296897/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219330/Y_Neobladder_An_Easy_Fast_and_Reliable_Procedure">Y-Neobladder: An Easy, Fast, and Reliable Procedure</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, 2005</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objectives. To describe the operative technique of a new, Y-shaped, ileal neobladder and report t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objectives. To describe the operative technique of a new, Y-shaped, ileal neobladder and report the clinical and functional outcomes to add a contribution to the most discussed issues about orthotopic neobladders, in particular related to the problem of the prevention of strictures of ureteral-neobladder anastomoses. Methods. Between January 1999 and June 2002, 50 patients (41 men and 9 women) underwent radical cystectomy and Y-shaped orthotopic neobladder reconstruction. The following parameters were considered: operative time, complications, and functional outcomes (evaluated with voiding chart and a questionnaire analyzing continence). Urodynamic studies were performed in the first 20 patients. Results. The operative time for neobladder reconstruction was 15 to 20 minutes. No severe complications or significant metabolic complications were recorded. Only 1 case of unilateral stricture of the ureteralneobladder anastomosis was recorded (1% of renal units); the stricture was easily treated with a retrograde endoscopic approach. Daytime and nighttime continence was good or satisfactory in 90% and 85% of patients, respectively. One year after surgery, the average maximal neobladder capacity was 390 mL, and the average pressure at maximal capacity was 15 cm H 2 O. Conclusions. The ileal Y-shaped orthotopic neobladder had good functional outcomes comparable to most popular orthotopic neobladders. Moreover, the surgical technique of the Y-neobladder is easy, rapid, and reliable. In particular, the Y-neobladder seemed to reduce, in our experience, the occurrence of strictures at the ureteral-neobladder anastomosis, because it permits a perfectly aligned anastomosis without mobilization of the ureters.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9a8f3343b24855e7caa23abc25310f3f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296897,"asset_id":33219330,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296897/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219330"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219330"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219330; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219330]").text(description); $(".js-view-count[data-work-id=33219330]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219330; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219330']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9a8f3343b24855e7caa23abc25310f3f" } } $('.js-work-strip[data-work-id=33219330]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219330,"title":"Y-Neobladder: An Easy, Fast, and Reliable Procedure","internal_url":"https://www.academia.edu/33219330/Y_Neobladder_An_Easy_Fast_and_Reliable_Procedure","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296897,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296897/thumbnails/1.jpg","file_name":"Y-neobladder_An_easy_fast_and_reliable_p20170527-12659-1h7mr3k.pdf","download_url":"https://www.academia.edu/attachments/53296897/download_file","bulk_download_file_name":"Y_Neobladder_An_Easy_Fast_and_Reliable_P.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296897/Y-neobladder_An_easy_fast_and_reliable_p20170527-12659-1h7mr3k-libre.pdf?1495898476=\u0026response-content-disposition=attachment%3B+filename%3DY_Neobladder_An_Easy_Fast_and_Reliable_P.pdf\u0026Expires=1740038174\u0026Signature=WiN50ImRVT4hGJr6LLhZrNtHt3vKz16wHvI0-4F1dOeyyFxOdpg0trrfh-YecAa3BTRpoO5iXGgEZM38Y0fzLNAy8oeh2zzXVkLr8y1b3yZPGhORNKFhAjc33w8DryUOX-igF3N4RAwMSiqyhlQ2Bw6TZLw9moPIDJKTDwh9seubhxS1KLS2CG-eNlIeoqwlJ49ujxJvAZ74SXq3v1dM13nFkUo8-dTy4ZSVUcdUOaikJm6VChPDBA0Vwcml94qrbUcf6Rz8bA2hh2vMAjpedcJ5O-GKtGeumo88RgMYiUbHM8CN0jBlETXQc25xt0V5eZ~qJC2q7qhB7ATLCbUcog__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219329"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219329/Study_of_Lymphatic_Drainage_by_SPECT_CT_Fusion_Images_for_Pelvic_Irradiation_of_Prostate_Cancer"><img alt="Research paper thumbnail of Study of Lymphatic Drainage by SPECT-CT Fusion Images for Pelvic Irradiation of Prostate Cancer" class="work-thumbnail" src="https://attachments.academia-assets.com/53296899/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219329/Study_of_Lymphatic_Drainage_by_SPECT_CT_Fusion_Images_for_Pelvic_Irradiation_of_Prostate_Cancer">Study of Lymphatic Drainage by SPECT-CT Fusion Images for Pelvic Irradiation of Prostate Cancer</a></div><div class="wp-workCard_item"><span>International Journal of Radiation Oncology*Biology*Physics</span><span>, 2005</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Purpose/Objective: Several studies suggest the need of pelvic irradiation in patients with high-r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Purpose/Objective: Several studies suggest the need of pelvic irradiation in patients with high-risk of subclinical nodal involvement. Usually, internal and external iliac nodes are included in the treatment volume but no precise information on the pathway of lymphatic drainage is available. The present study aims to investigate the in vivo drainage pathway of lymphatic spread by using lymphoscintigraphy and SPECT-CT fusion to identify the location of the first echelon of potentially involved nodes. Materials/Methods: Fifteen patients with prostate cancer, candidated to surgery and included in a trial studying the sentinel node technique, have been enrolled. Lymphoscintigraphy and SPECT images were obtained 1 and 2-3 hours after intra-prostate trans-rectal injection of 115 MBq of 99mTc-nano-colloid. The first images allowed to identify the first echelon of nodal drainage (sentinel node) and the following images the other pelvic lymph nodes. After the acquisition of SPECT, a spiral CT-scan, with slices of 5 mm thickness was performed. SPECT images were fused with CT images by using external fiducial markers. The volumes of interest were drawn on CT. CTV included prostate, seminal vesicles, and internal and external iliac nodes; bladder and rectum were also delineated. Afterwards, the sentinel node was identified and contoured on SPECT-CT fusion images. The treatment plan using 3D-CRT by 4 fields technique was obtained displaying isodose curves and DVHs for all the delineated structures including sentinel nodes. Results: No patient experienced relevant toxicity related to intra-prostate trans-rectal injection. The sentinel node was identified inside the CTV in all the 15 cases. It was located in external iliac in 60% of cases and in internal iliac nodes in 40%. The sentinel node was identified at the level of the upper third of internal or external iliac nodes in 80% of patients whereas it was located in the central third in 20%. In no case, the sentinel node was found in the lower third of internal or external iliac nodes. The mean dose to the sentinel node was 102.5% (range: 100.2-103.7%) with reference to the ICRU point.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b50bd1993dfec36d5d15a3f3191faf7a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296899,"asset_id":33219329,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296899/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219329"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219329"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219329; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219329]").text(description); $(".js-view-count[data-work-id=33219329]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219329; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219329']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b50bd1993dfec36d5d15a3f3191faf7a" } } $('.js-work-strip[data-work-id=33219329]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219329,"title":"Study of Lymphatic Drainage by SPECT-CT Fusion Images for Pelvic Irradiation of Prostate Cancer","internal_url":"https://www.academia.edu/33219329/Study_of_Lymphatic_Drainage_by_SPECT_CT_Fusion_Images_for_Pelvic_Irradiation_of_Prostate_Cancer","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296899,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296899/thumbnails/1.jpg","file_name":"j.ijrobp.2005.07.52320170527-12656-mpf0fr.pdf","download_url":"https://www.academia.edu/attachments/53296899/download_file","bulk_download_file_name":"Study_of_Lymphatic_Drainage_by_SPECT_CT.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296899/j.ijrobp.2005.07.52320170527-12656-mpf0fr-libre.pdf?1495898474=\u0026response-content-disposition=attachment%3B+filename%3DStudy_of_Lymphatic_Drainage_by_SPECT_CT.pdf\u0026Expires=1740038174\u0026Signature=VcfKW8B0SAeipeCIGgZhB-x8kuNAhqhjydsDrrd3IBLBn0vNQYFlfcNXic3BUjcWXnJZEbL1T~RHPt70CYdDm0umwT2fvruOAl4GouvS3QTiFVDTkuGGpNGCpGamBhUNvqxY62UxJYyIG3Qoyu2SrOwzC-imfM9i-RoLkzaI3iNRJ~bbcT~ep743VJMMcHOZnH063zq0yYHbOM02JnTHAyocWdt2BSc3Oln8iw7MpRcY4RNJj3oAnV~HpeY8sKYoPJSdxfBXFCuJEg~Nh3kTFeNdQHQm0N2XLwcSLmrj1nXWoGKiB5zpyljKzCfwp8LC5cSz84r937m8EHTX3Zo-Nw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219326"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219326/A_Single_center_Analysis_on_the_Learning_Curve_of_Male_to_Female_Penoscrotal_Vaginoplasty_by_Multiple_Surgical_Measures"><img alt="Research paper thumbnail of A Single-center Analysis on the Learning Curve of Male-to-Female Penoscrotal Vaginoplasty by Multiple Surgical Measures" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219326/A_Single_center_Analysis_on_the_Learning_Curve_of_Male_to_Female_Penoscrotal_Vaginoplasty_by_Multiple_Surgical_Measures">A Single-center Analysis on the Learning Curve of Male-to-Female Penoscrotal Vaginoplasty by Multiple Surgical Measures</a></div><div class="wp-workCard_item"><span>Urology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To asses and quantify the learning curve (LC) of the penoscrotal inversion flap vaginoplasty (PSV...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To asses and quantify the learning curve (LC) of the penoscrotal inversion flap vaginoplasty (PSV). We retrospectively reviewed clinical records of 69 patients who underwent PSV from January 2005 to January 2015. Two validated methods were used: a scatterplot representation and a splitting group. We selected as primary outcomes the operative time and vaginal depth. Surgical outcomes including blood losses, hospital stay, and postoperative complications such as vaginal stenosis or atresia or urethral meatus stenosis were also evaluated. The overall median operative time was 245 minutes. Severe intraoperative complications were not reported. The overall incidence of postoperative major complications was 21.7 %, most of them being urethral issues. The splitting group analysis revealed a statistically remarkable difference between groups for the operative time (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .01), the vaginal depth (P = .01), the hospital stay (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .01), and the intraoperative complication rate (P = .01). On the contrary, no differences were evidenced between the cohorts for the amount of blood loss (P = .08). The scatterplot logarithmic analysis demonstrated a clear visible LC for most parameters. The operative time showed a sharp decrease within the first 20-30 cases, reaching a plateau after 40 cases. Considering the analysis of the vaginal depth, the logarithmic scatterplot curve evidenced a slight increase within the first 10 cases, reaching a clear stabilization after nearly 30-40 cases. An evident LC for PSV is detectable, consisting of at least 40 cases needed to the surgical team to develop adequate skills to guarantee a safe and high-quality procedure.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219326"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219326"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219326; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219326]").text(description); $(".js-view-count[data-work-id=33219326]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219326; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219326']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219326]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219326,"title":"A Single-center Analysis on the Learning Curve of Male-to-Female Penoscrotal Vaginoplasty by Multiple Surgical Measures","internal_url":"https://www.academia.edu/33219326/A_Single_center_Analysis_on_the_Learning_Curve_of_Male_to_Female_Penoscrotal_Vaginoplasty_by_Multiple_Surgical_Measures","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219325"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219325/POD_11_06_Use_of_the_adjustable_continence_therapy_for_post_prostatatectomy_urodynamic_stress_urinary_incontinence"><img alt="Research paper thumbnail of POD-11.06: Use of the adjustable continence therapy for post prostatatectomy urodynamic stress urinary incontinence" class="work-thumbnail" src="https://attachments.academia-assets.com/53296894/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219325/POD_11_06_Use_of_the_adjustable_continence_therapy_for_post_prostatatectomy_urodynamic_stress_urinary_incontinence">POD-11.06: Use of the adjustable continence therapy for post prostatatectomy urodynamic stress urinary incontinence</a></div><div class="wp-workCard_item"><span>Urology</span><span>, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">2/10 became dry, 6 improved (one underwear liner) and 2 were unchanged. Eleven patients had previ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">2/10 became dry, 6 improved (one underwear liner) and 2 were unchanged. Eleven patients had previously undergone external beam radiotherapy prior to balloon implantation. Four (33.3%) were dry following adjustment, 2(24%) were improved and 5/11 (42.7%) were unchanged at last follow up. 4 reports of denovo urge had resolution of symptoms following anticholinergic therapy within one month of surgery.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="87a9456400057f16e70a7f75dae2b684" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296894,"asset_id":33219325,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296894/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219325"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219325"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219325; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219325]").text(description); $(".js-view-count[data-work-id=33219325]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219325; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219325']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "87a9456400057f16e70a7f75dae2b684" } } $('.js-work-strip[data-work-id=33219325]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219325,"title":"POD-11.06: Use of the adjustable continence therapy for post prostatatectomy urodynamic stress urinary incontinence","internal_url":"https://www.academia.edu/33219325/POD_11_06_Use_of_the_adjustable_continence_therapy_for_post_prostatatectomy_urodynamic_stress_urinary_incontinence","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296894,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296894/thumbnails/1.jpg","file_name":"j.urology.2007.06.15220170527-12653-ihd0he.pdf","download_url":"https://www.academia.edu/attachments/53296894/download_file","bulk_download_file_name":"POD_11_06_Use_of_the_adjustable_continen.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296894/j.urology.2007.06.15220170527-12653-ihd0he-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3DPOD_11_06_Use_of_the_adjustable_continen.pdf\u0026Expires=1740038174\u0026Signature=IHqGqas3AHLrLGIRyxZksHolq-5whr5rz9OlPNdq6yiI1l~hb7V-8yCuda6GsckkjsB1NzmLvoD3xc34gAVDWz~C3n3PSeN3foiB9bIIQ11bS8aCkmx7m0LQyqkEjOiRGz6lH6Tlxp9v0Bd5LikBytzhAY34s~OHd3njgscbx-gEw-48EqL-cWsOI2-nsIjZgLw5SkWZiwvFPJTuWB0qNFjTflo0DGMe5c-sj9SgfdQncS6QUE~3l68RMzU5m2HSUywKvEXaxHYCv0qXyvEvjHVVLvWuvnWxQMUG5q07vL2tr5cvz3J0uqNPh~FaymcKrFmrkzpKtAD~QLvsMPlS8A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219324"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219324/361Sexual_disorders_in_hemodialysed_female_patients"><img alt="Research paper thumbnail of 361Sexual disorders in hemodialysed female patients" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219324/361Sexual_disorders_in_hemodialysed_female_patients">361Sexual disorders in hemodialysed female patients</a></div><div class="wp-workCard_item"><span>Eur Urol Suppl</span><span>, 2005</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219324"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219324"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219324; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219324]").text(description); $(".js-view-count[data-work-id=33219324]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219324; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219324']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219324]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219324,"title":"361Sexual disorders in hemodialysed female patients","internal_url":"https://www.academia.edu/33219324/361Sexual_disorders_in_hemodialysed_female_patients","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219323"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219323/Is_There_an_Optimal_Time_for_Intracavernous_Prostaglandin_E1_Rehabilitation_Following_Nonnerve_Sparing_Radical_Prostatectomy_Results_From_a_Hemodynamic_Prospective_Study"><img alt="Research paper thumbnail of Is There an Optimal Time for Intracavernous Prostaglandin E1 Rehabilitation Following Nonnerve Sparing Radical Prostatectomy? Results From a Hemodynamic Prospective Study" class="work-thumbnail" src="https://attachments.academia-assets.com/53296891/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219323/Is_There_an_Optimal_Time_for_Intracavernous_Prostaglandin_E1_Rehabilitation_Following_Nonnerve_Sparing_Radical_Prostatectomy_Results_From_a_Hemodynamic_Prospective_Study">Is There an Optimal Time for Intracavernous Prostaglandin E1 Rehabilitation Following Nonnerve Sparing Radical Prostatectomy? Results From a Hemodynamic Prospective Study</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, Jun 1, 2003</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Purpose: Previous studies have shown that early intracavernous prostaglandin E1 injection may red...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Purpose: Previous studies have shown that early intracavernous prostaglandin E1 injection may reduce significantly the incidence of veno-occlusive dysfunction before spontaneous erections recover after nerve sparing radical prostatectomy. We identify the more convenient postoperative timing for successful intracavernous injection rehabilitation in a series of patients who underwent nonnerve sparing radical prostatectomy.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f6d9bfb40fd757ae5bfb5404864f712a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296891,"asset_id":33219323,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296891/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219323"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219323"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219323; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219323]").text(description); $(".js-view-count[data-work-id=33219323]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219323; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219323']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f6d9bfb40fd757ae5bfb5404864f712a" } } $('.js-work-strip[data-work-id=33219323]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219323,"title":"Is There an Optimal Time for Intracavernous Prostaglandin E1 Rehabilitation Following Nonnerve Sparing Radical Prostatectomy? Results From a Hemodynamic Prospective Study","internal_url":"https://www.academia.edu/33219323/Is_There_an_Optimal_Time_for_Intracavernous_Prostaglandin_E1_Rehabilitation_Following_Nonnerve_Sparing_Radical_Prostatectomy_Results_From_a_Hemodynamic_Prospective_Study","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296891,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296891/thumbnails/1.jpg","file_name":"01.ju.0000064939.04658.1520170527-12653-1k1j7i6.pdf","download_url":"https://www.academia.edu/attachments/53296891/download_file","bulk_download_file_name":"Is_There_an_Optimal_Time_for_Intracavern.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296891/01.ju.0000064939.04658.1520170527-12653-1k1j7i6-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3DIs_There_an_Optimal_Time_for_Intracavern.pdf\u0026Expires=1740038174\u0026Signature=a5f2B0AySiPLFnIdei2XJlrez36s6QowHN0SSzxqKhyGF563x5EwzwvQ8OfVbA6qiJbipF-cuwqeG3pjIy8S7fezCgdi3sxfSwL5SUPs4DMB~WyVP3fhtJhiBCRH7Mz4F9oGC3CTQI3tztUb98JmKuUIuf5iZ~yDV491CxlNQiZfidaJrpGsJuW0XmfVrEPtnhlzYUiVVCKyK4j6x2UlC4k5oumNV409HMk9MWS3s3MaKoQ2yFNHtFX3f3NSIBo05hQMMO~gByIMG63-LG-Tdi-MSuPi8fVPPijJTkLGLMwyvUJzyHvYyj13IMV2~pgR4Rai9r8bitzodiuMCRDU7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219322"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219322/Sentinel_lymph_node_detection_during_radical_prostatectomy_for_prostate_cancer_current_evidence_and_results_of_our_experience"><img alt="Research paper thumbnail of Sentinel lymph node detection during radical prostatectomy for prostate cancer: current evidence and results of our experience" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219322/Sentinel_lymph_node_detection_during_radical_prostatectomy_for_prostate_cancer_current_evidence_and_results_of_our_experience">Sentinel lymph node detection during radical prostatectomy for prostate cancer: current evidence and results of our experience</a></div><div class="wp-workCard_item"><span>Urologia</span><span>, Jan 21, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A sentinel lymph node (SNL) is the primary landing zone of cancer cells that spreads through the ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A sentinel lymph node (SNL) is the primary landing zone of cancer cells that spreads through the lymphatic vessels. The rational of the detection of sentinel node (SLN) during radical prostatectomy (RP) for prostate cancer (PCa) is the removal of the first nodal stations to provide a restriction of the template of node dissection. A review of the outcomes of SNL detection during RP for PCa was performed. A systematic review of the literature was conducted, searching on PubMed and Web of Science, using the following keywords: lymph node dissection, prostatic neoplasm, sentinel node. Twenty articles were selected and analyzed including over 2000 PCa patients. Although promising and technically feasible, many points remain to be clarified before clinical application can be recommended. The technique of SNL detection is feasible and provides a higher sensitivity and detection rate than standard lymphadenectomy, especially for organ-confined tumors. Larger series and long-term follow-up ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219322"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219322"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219322; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219322]").text(description); $(".js-view-count[data-work-id=33219322]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219322; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219322']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219322]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219322,"title":"Sentinel lymph node detection during radical prostatectomy for prostate cancer: current evidence and results of our experience","internal_url":"https://www.academia.edu/33219322/Sentinel_lymph_node_detection_during_radical_prostatectomy_for_prostate_cancer_current_evidence_and_results_of_our_experience","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219321"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219321/Metastasis_Markers_in_Bladder_Cancer_A_Review_of_the_Literature_and_Clinical_Considerations"><img alt="Research paper thumbnail of Metastasis Markers in Bladder Cancer: A Review of the Literature and Clinical Considerations" class="work-thumbnail" src="https://attachments.academia-assets.com/53296893/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219321/Metastasis_Markers_in_Bladder_Cancer_A_Review_of_the_Literature_and_Clinical_Considerations">Metastasis Markers in Bladder Cancer: A Review of the Literature and Clinical Considerations</a></div><div class="wp-workCard_item"><span>European Urology</span><span>, Sep 30, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Cancer invasion and metastasis develop through a sequence of processes involving loss of cell-cel...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Cancer invasion and metastasis develop through a sequence of processes involving loss of cell-cell and cell-matrix adhesions, proteolysis and induction of angiogenesis. We reviewed the current literature on the molecules that have been shown to play a significant role in these three steps of metastatisation in bladder cancer (BC) cells and their host microenvironment. Particular emphasis was given to markers that are assessable through immunohistochemistry and for which an additional prognostic value over the TNM variables has been recognized, in order to identify a subset of tumour markers readily available for application in daily clinical practice.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="85d8c6b3be162b0a54a0a4427d5e04ce" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296893,"asset_id":33219321,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296893/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219321"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219321"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219321; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219321]").text(description); $(".js-view-count[data-work-id=33219321]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219321; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219321']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "85d8c6b3be162b0a54a0a4427d5e04ce" } } $('.js-work-strip[data-work-id=33219321]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219321,"title":"Metastasis Markers in Bladder Cancer: A Review of the Literature and Clinical Considerations","internal_url":"https://www.academia.edu/33219321/Metastasis_Markers_in_Bladder_Cancer_A_Review_of_the_Literature_and_Clinical_Considerations","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296893,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296893/thumbnails/1.jpg","file_name":"j.eururo.2004.04.00120170527-12659-zcdua4.pdf","download_url":"https://www.academia.edu/attachments/53296893/download_file","bulk_download_file_name":"Metastasis_Markers_in_Bladder_Cancer_A_R.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296893/j.eururo.2004.04.00120170527-12659-zcdua4-libre.pdf?1495898477=\u0026response-content-disposition=attachment%3B+filename%3DMetastasis_Markers_in_Bladder_Cancer_A_R.pdf\u0026Expires=1740038174\u0026Signature=TcRy-dMg7~aga6QJFgb44cYGsO3P7-PFu7SV6R2mx~TvdE2VSiOo7HaPcLJbwHXKgdFcm2MW3n33jP0PH-ZEPxl2mujhEHtj3TdjXBODaJf8cw~RFMWN0YgivvhpiQ5TqK8gjSI2XTrtMcnZ6EMzI7w~FlNWITLEWhUpQtz2E~oTOwy8N3d~zYexvcgDXZGJGC5mBZNgtI27WN2cx1gUWea6Fd5FM1SdHYw-6DVKxn747YwPe30ou1JA9ljoa1ieT7RoewZcuupyCenXzx6MOWBtxYfQUnLHeDrByYc2zDXY0zIfIX8BLVZTaHTvG6gxy0n7wCH0mB525j5ZZo~LeA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219320"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219320/New_Insights_Into_the_Pathogenesis_of_Penile_Shortening_After_Radical_Prostatectomy_and_the_Role_of_Postoperative_Sexual_Function"><img alt="Research paper thumbnail of New Insights Into the Pathogenesis of Penile Shortening After Radical Prostatectomy and the Role of Postoperative Sexual Function" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219320/New_Insights_Into_the_Pathogenesis_of_Penile_Shortening_After_Radical_Prostatectomy_and_the_Role_of_Postoperative_Sexual_Function">New Insights Into the Pathogenesis of Penile Shortening After Radical Prostatectomy and the Role of Postoperative Sexual Function</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, Aug 1, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">PURPOSE: We assessed penile changes after radical prostatectomy by performing serial penile measu...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">PURPOSE: We assessed penile changes after radical prostatectomy by performing serial penile measurements. The potential effect of nerve sparing surgery and the recovery of erectile function on the degree of penile shortening were also evaluated.MATERIALS AND METHODS: A total of 126 consecutive patients were enrolled. Penile measurements were taken immediately before surgery, at catheter removal, and at 3, 6 and 12 months postoperatively. Sexual function was assessed at baseline and at 3, 6 and 12 months using the erectile function domain of the International Index of Erectile Function.RESULTS: The maximum degree of shortening was noted at the time of catheter removal (mean 0.84 cm, CI 0.62-1.06, p <0.0001 for stretched penis). All penile parameters showed a lesser but significant decrease at all subsequent intervals. Univariate analysis revealed that baseline penile length was the only variable significantly associated with stretched penile length at catheter removal. Age, nerve sparing surgery and the recovery of erectile function were strong predictors of penile size 1 year after surgery. Multivariate analysis showed that nerve sparing surgery (<0.0001) and the recovery of erectile function (p = 0.053) were independent predictors of the final changes in penile size.CONCLUSIONS: Penile shortening after radical prostatectomy peaks at the time of catheter removal and it continues to a lesser but still significant degree for at least 1 year. Nerve sparing surgery and recovery of erectile function appeared to have an independent protective effect on penile length loss at 1 year. These figures should be taken in consideration when counseling patients for radical prostatectomy.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219320"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219320"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219320; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219320]").text(description); $(".js-view-count[data-work-id=33219320]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219320; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219320']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219320]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219320,"title":"New Insights Into the Pathogenesis of Penile Shortening After Radical Prostatectomy and the Role of Postoperative Sexual Function","internal_url":"https://www.academia.edu/33219320/New_Insights_Into_the_Pathogenesis_of_Penile_Shortening_After_Radical_Prostatectomy_and_the_Role_of_Postoperative_Sexual_Function","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219319"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219319/Can_MRI_Predict_Which_Patients_Are_Most_Likely_to_Benefi_t_from_Percutaneous_Positioning_of_Volume_Adjustable_Balloon_Devices"><img alt="Research paper thumbnail of Can MRI Predict Which Patients Are Most Likely to Benefi t from Percutaneous Positioning of Volume-Adjustable Balloon Devices?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219319/Can_MRI_Predict_Which_Patients_Are_Most_Likely_to_Benefi_t_from_Percutaneous_Positioning_of_Volume_Adjustable_Balloon_Devices">Can MRI Predict Which Patients Are Most Likely to Benefi t from Percutaneous Positioning of Volume-Adjustable Balloon Devices?</a></div><div class="wp-workCard_item"><span>Urol Int</span><span>, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To assess whether magnetic resonance imaging (MRI) is useful in predicting which patients affecte...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To assess whether magnetic resonance imaging (MRI) is useful in predicting which patients affected by stress urinary incontinence (SUI) will benefit from a new anti-incontinence therapy named adjustable continence therapy (AC). We prospectively evaluated a group of 25 female patients affected by SUI and treated with ACT. Before and after treatment all patients were clinically assessed by physical examination, urodynamic evaluation and pad test. All patients had an MR examination before and 3 and 12 months after ACT surgery to compare the position of the bladder neck in relation to the pubococcygeal line (PCL). 21/25 (84%) patients were improved; 16 (64%) of these patients were dry and 5 (20%) significantly improved. Before treatment, the mean PCL distance was significantly different (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.01) between the responsive and the non-responsive groups. MRI provides an effective radiological method to predict the efficacy of the ACT.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219319"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219319"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219319; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219319]").text(description); $(".js-view-count[data-work-id=33219319]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219319; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219319']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219319]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219319,"title":"Can MRI Predict Which Patients Are Most Likely to Benefi t from Percutaneous Positioning of Volume-Adjustable Balloon Devices?","internal_url":"https://www.academia.edu/33219319/Can_MRI_Predict_Which_Patients_Are_Most_Likely_to_Benefi_t_from_Percutaneous_Positioning_of_Volume_Adjustable_Balloon_Devices","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="7039262" id="papers"><div class="js-work-strip profile--work_container" data-work-id="33219340"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219340/Beta_2_glycoprotein_1_and_alpha_1_antitrypsin_as_urinary_markers_of_renal_cancer_in_von_Hippel_Lindau_patients"><img alt="Research paper thumbnail of Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel–Lindau patients" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219340/Beta_2_glycoprotein_1_and_alpha_1_antitrypsin_as_urinary_markers_of_renal_cancer_in_von_Hippel_Lindau_patients">Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel–Lindau patients</a></div><div class="wp-workCard_item"><span>Biomarkers</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Von Hippel-Lindau disease (VHLD) is a rare inherited neoplastic syndrome. Among all the VHLD-asso...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Von Hippel-Lindau disease (VHLD) is a rare inherited neoplastic syndrome. Among all the VHLD-associated tumors, clear cell renal cell carcinoma (ccRCC) is the major cause of death. The aim of this paper is the discovery of new non-invasive biomarker for the monitoring of VHLD patients. We compared the urinary proteome of VHLD patients, ccRCC patients and healthy volunteers. Among all differentially expressed proteins, alpha-1-antitrypsin (A1AT) and APOH (beta-2-glycoprotein-1) are strongly over-abundant only in the urine of VHLD patients with a history of ccRCC. A1AT and APOH could be promising non-invasive biomarkers.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219340"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219340"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219340; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219340]").text(description); $(".js-view-count[data-work-id=33219340]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219340; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219340']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219340]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219340,"title":"Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel–Lindau patients","internal_url":"https://www.academia.edu/33219340/Beta_2_glycoprotein_1_and_alpha_1_antitrypsin_as_urinary_markers_of_renal_cancer_in_von_Hippel_Lindau_patients","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219339"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219339/1012_Sentinel_Lymph_Node_Surgery_in_Prostate_Cancer_Results_of_a_Prospective_Study_with_a_10_Years_Follow_Up"><img alt="Research paper thumbnail of 1012 Sentinel Lymph Node Surgery in Prostate Cancer: Results of a Prospective Study with a 10 Years Follow Up" class="work-thumbnail" src="https://attachments.academia-assets.com/53296898/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219339/1012_Sentinel_Lymph_Node_Surgery_in_Prostate_Cancer_Results_of_a_Prospective_Study_with_a_10_Years_Follow_Up">1012 Sentinel Lymph Node Surgery in Prostate Cancer: Results of a Prospective Study with a 10 Years Follow Up</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2010</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c584585d377791971f58f6368dd4c9fe" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296898,"asset_id":33219339,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296898/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219339"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219339"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219339; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219339]").text(description); $(".js-view-count[data-work-id=33219339]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219339; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219339']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c584585d377791971f58f6368dd4c9fe" } } $('.js-work-strip[data-work-id=33219339]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219339,"title":"1012 Sentinel Lymph Node Surgery in Prostate Cancer: Results of a Prospective Study with a 10 Years Follow Up","internal_url":"https://www.academia.edu/33219339/1012_Sentinel_Lymph_Node_Surgery_in_Prostate_Cancer_Results_of_a_Prospective_Study_with_a_10_Years_Follow_Up","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296898,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296898/thumbnails/1.jpg","file_name":"s1569-9056_2810_2960991-820170527-12659-tkejl8.pdf","download_url":"https://www.academia.edu/attachments/53296898/download_file","bulk_download_file_name":"1012_Sentinel_Lymph_Node_Surgery_in_Pros.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296898/s1569-9056_2810_2960991-820170527-12659-tkejl8-libre.pdf?1495898476=\u0026response-content-disposition=attachment%3B+filename%3D1012_Sentinel_Lymph_Node_Surgery_in_Pros.pdf\u0026Expires=1740038174\u0026Signature=aH~5ectJkIgUEkOzIi3mMPlTvgnUcwqcvPfSIUVWfrT3ads1FoYK962vfLdMdTsUHO2gFMYHWi2TNTeVbfqYPdVgrwwKNsqK8vT-c~mbH58iYvd~pp6FeBF9RPdy2jhxvZj62HtfpGlcRon2um5u1rhB5WrKo0nNTbVB5lpBuBAeL8QqVs-HabwpwatMBkZgVb9gqRFIxQAhEsUV9ENXt0pgAL0rj9iABjjuNGnGZiIRhaBOLrYZcmdeTpvUTlbT-Jh7OCle2uZf1A828gfC0hLTC5-LtcP8haGJNbu8ker64IrOOG0cVSUmychJ5AiLpJIT2hobX6P2CokekrfRuA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219338"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219338/Morphological_and_Functional_Anatomy_of_Male_Pelvis"><img alt="Research paper thumbnail of Morphological and Functional Anatomy of Male Pelvis" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219338/Morphological_and_Functional_Anatomy_of_Male_Pelvis">Morphological and Functional Anatomy of Male Pelvis</a></div><div class="wp-workCard_item"><span>Male Stress Urinary Incontinence</span><span>, 2015</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219338"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219338"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219338; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219338]").text(description); $(".js-view-count[data-work-id=33219338]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219338; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219338']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219338]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219338,"title":"Morphological and Functional Anatomy of Male Pelvis","internal_url":"https://www.academia.edu/33219338/Morphological_and_Functional_Anatomy_of_Male_Pelvis","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219337"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219337/Evaluation_of_the_efficacy_and_patient_compliance_to_different_treatment_modalities_for_erectile_dysfunction_after_nonnerve_sparing_radical_retropubic_prostatectomy_NNSRRP_"><img alt="Research paper thumbnail of Evaluation of the efficacy and patient compliance to different treatment modalities for erectile dysfunction after nonnerve sparing radical retropubic prostatectomy (NNSRRP)" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219337/Evaluation_of_the_efficacy_and_patient_compliance_to_different_treatment_modalities_for_erectile_dysfunction_after_nonnerve_sparing_radical_retropubic_prostatectomy_NNSRRP_">Evaluation of the efficacy and patient compliance to different treatment modalities for erectile dysfunction after nonnerve sparing radical retropubic prostatectomy (NNSRRP)</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2003</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219337"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219337"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219337; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219337]").text(description); $(".js-view-count[data-work-id=33219337]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219337; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219337']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219337]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219337,"title":"Evaluation of the efficacy and patient compliance to different treatment modalities for erectile dysfunction after nonnerve sparing radical retropubic prostatectomy (NNSRRP)","internal_url":"https://www.academia.edu/33219337/Evaluation_of_the_efficacy_and_patient_compliance_to_different_treatment_modalities_for_erectile_dysfunction_after_nonnerve_sparing_radical_retropubic_prostatectomy_NNSRRP_","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219336"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219336/759_Does_saline_hypertonic_solution_reduce_the_risk_of_Turp_syndrome"><img alt="Research paper thumbnail of 759 Does saline hypertonic solution reduce the risk of Turp syndrome?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219336/759_Does_saline_hypertonic_solution_reduce_the_risk_of_Turp_syndrome">759 Does saline hypertonic solution reduce the risk of Turp syndrome?</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2004</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219336"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219336"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219336; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219336]").text(description); $(".js-view-count[data-work-id=33219336]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219336; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219336']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219336]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219336,"title":"759 Does saline hypertonic solution reduce the risk of Turp syndrome?","internal_url":"https://www.academia.edu/33219336/759_Does_saline_hypertonic_solution_reduce_the_risk_of_Turp_syndrome","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219335"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219335/Cavernous_hemangioma_of_the_spongious_body_of_the_urethra_a_case_report"><img alt="Research paper thumbnail of Cavernous hemangioma of the spongious body of the urethra: a case report" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219335/Cavernous_hemangioma_of_the_spongious_body_of_the_urethra_a_case_report">Cavernous hemangioma of the spongious body of the urethra: a case report</a></div><div class="wp-workCard_item"><span>Rivista Urologia</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Urethral hemangiomas are rare and benign tumors, probably originating from a unipotent angioblast...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Urethral hemangiomas are rare and benign tumors, probably originating from a unipotent angioblastic stem cell. They can vary in size and the clinical appearance can range from asymptomatic lesions to urethral bleeding or gross hematuria. We present the case of an 18-year-old male, with a history of urethral bleeding. Cystourethoscopy revealed a solitary bulging mass into the lumen, about 6 cm far from the external meatus. Doppler study confirmed that the lesion was in communication with the vessels of the left spongious body. The patient underwent surgical removal of the lesion. The post-procedure Doppler study revealed an inflammation-based remodeling of the spongoius urethra and the absence of the previous vascular connection. At the time of publication the patient is still symptom-free. The surgical removal of urethral hemangiomas is by far the technique of choice for treating such lesions in young patients, thus avoiding side effects of LASER treatments.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219335"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219335"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219335; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219335]").text(description); $(".js-view-count[data-work-id=33219335]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219335; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219335']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219335]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219335,"title":"Cavernous hemangioma of the spongious body of the urethra: a case report","internal_url":"https://www.academia.edu/33219335/Cavernous_hemangioma_of_the_spongious_body_of_the_urethra_a_case_report","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219334"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219334/Prostate_biopsy_after_abdominoperineal_resection_a_diagnostic_challenge"><img alt="Research paper thumbnail of Prostate biopsy after abdominoperineal resection: a diagnostic challenge" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219334/Prostate_biopsy_after_abdominoperineal_resection_a_diagnostic_challenge">Prostate biopsy after abdominoperineal resection: a diagnostic challenge</a></div><div class="wp-workCard_item"><span>Rivista Urologia</span><span>, 2013</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Prostate biopsy in patients who underwent abdominoperineal resection (APR) of the rectum is commo...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Prostate biopsy in patients who underwent abdominoperineal resection (APR) of the rectum is commonly considered a technical challenge even for experienced urologists, although tissue diagnosis is essential in prostate cancer management. Transperitoneal, transperineal and transgluteal approaches have been reported, under US, CT or MRI guidance. Transperineal biopsy seems to be the safest and most cost-effective technique. At our institution we developed a modified transperineal biopsy approach with combined transperineal and suprapubic US guidance. Here we report the cases of two patients who came to our institution for PSA raise years after APR procedure, describing in detail the modified transperineal technique and the results of tissue sampling.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219334"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219334"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219334; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219334]").text(description); $(".js-view-count[data-work-id=33219334]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219334; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219334']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219334]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219334,"title":"Prostate biopsy after abdominoperineal resection: a diagnostic challenge","internal_url":"https://www.academia.edu/33219334/Prostate_biopsy_after_abdominoperineal_resection_a_diagnostic_challenge","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219333"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219333/99_How_much_intuitive_is_the_da_Vinci_system_Validation_of_the_Intuitive_Surgical_System_training_practicum"><img alt="Research paper thumbnail of 99 How much intuitive is the da Vinci system? Validation of the Intuitive Surgical System training practicum" class="work-thumbnail" src="https://attachments.academia-assets.com/53296896/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219333/99_How_much_intuitive_is_the_da_Vinci_system_Validation_of_the_Intuitive_Surgical_System_training_practicum">99 How much intuitive is the da Vinci system? Validation of the Intuitive Surgical System training practicum</a></div><div class="wp-workCard_item"><span>European Urology Supplements</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The revolutionary technology of robotics has given the opportunity to experienced open surgeons a...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The revolutionary technology of robotics has given the opportunity to experienced open surgeons around the world to adapt to a new setting of minimal invasive surgery. Although the learning curve is not steep, it can by itself, hinder many of the advantages of a minimally invasive procedure. The purpose of the present study is to compare the systemic response of the well established minilaparotomy radical retropubic prostatectomy (RRP) with the robotic assisted radical prostatectomy (RALP) accomplished by a beginner console surgeon, by measuring the level of serum inflammatory cytokines (IL-1a, IL-6, IL-10, TNF-a, CRP). Materials and Methods: After obtaining approval from the ethical committee of the two institutions, a prospective nonrandomized study was conducted. From May 2008 to February 2009, 60 patients with clinically organ confined prostate cancer (cT1-2) that had been confirmed histologically, were included. Thirty consecutive patients (group A) underwent RRP from a single experienced surgeon in one institution, while RALP was offered in 30 consecutive patients (group B) in another institution by a single surgeon. Exclusion criteria were equal in both groups and no significant differences were observed in the preoperative variables. Blood samples were collected 24 h (T0) preoperatively and at 9h (T1), 24h (T2) and 48h (T3) postoperatively. HCt, Hgb, WBC were measured and IL-1a, IL-6, IL-10, TNF-a, CRP were assayed by ELISA. Independent sample t-test was used to calculate the statistical significance of differences. A p-value of less than 0.05 was considered statistically significant. Results: The two groups were comparable for age, BMI, preoperative PSA, specimen weight and volume. CRP (mg/L) was significantly elevated in group A, at T1 (mean 7.04 vs 4.65, P = 0.043), T2 (mean 12.00 vs 9.53, P = 0.001) and T3 (mean 18.92 vs 14.98, P = 0.003). IL-6 (Pg/mL) was also elevated in group A, at T1 (mean 40.63 vs 19.79, P = 0.001) and T2 (mean 34.86 vs 15.34, P = 0.001). Hct (%) was reduced in group A, at T3 (mean 34.53 vs 36.57, P = 0.033). Hgb (gr/dL) was also reduced in group A, at T2 (mean 11.14 vs 11.97, P = 0.01) and at T3 (mean 10.68 vs 12.35, P < 0.001). WBC was elevated in group A, at T1 (mean 12.90 vs 9.36, P < 0.001), T2 (mean 11.93 vs 8.73, P = 0.001), and at T3 (mean 9.90 vs 7.84, P = 0.012). Group A required transfusion with a mean of 2.2 (±0.64) PRBC, while no PRBC were provided in the RALP group. Operating time was significantly higher in the RALP group (mean 130.50 vs 252.50, P < 0.001).</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="77bbceafb3e19e9a6fd40f93800cea7c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296896,"asset_id":33219333,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296896/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219333"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219333"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219333; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219333]").text(description); $(".js-view-count[data-work-id=33219333]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219333; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219333']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "77bbceafb3e19e9a6fd40f93800cea7c" } } $('.js-work-strip[data-work-id=33219333]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219333,"title":"99 How much intuitive is the da Vinci system? Validation of the Intuitive Surgical System training practicum","internal_url":"https://www.academia.edu/33219333/99_How_much_intuitive_is_the_da_Vinci_system_Validation_of_the_Intuitive_Surgical_System_training_practicum","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296896,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296896/thumbnails/1.jpg","file_name":"s1569-9056_2811_2961427-920170527-12659-18j9lnm.pdf","download_url":"https://www.academia.edu/attachments/53296896/download_file","bulk_download_file_name":"99_How_much_intuitive_is_the_da_Vinci_sy.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296896/s1569-9056_2811_2961427-920170527-12659-18j9lnm-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3D99_How_much_intuitive_is_the_da_Vinci_sy.pdf\u0026Expires=1740038174\u0026Signature=Rtz4xoyx1k~wmPr54Z-aYF5UFOgD21yZuU1V2fHthatFnKSlUkft~twCvb8KcC5HX0uFfm9MnxKbrBxUCU4RzldBA5hFUde63DKd59f~Je5WsxQ8yMHvbxF1BGOPQqhYnR45FHzQOMn-ILPZT0Ux86vEw0D7J6BywQXmvTs53IaTA0ioiqIWxU9G3lLRTAvujkZS~giocP6-RFPhnNiYmiHGT39LrmcvrBR2fbS-XxBxmluhxI7rjGs~5u7m3d0FDPKe1fpHBLvE-PnMiww-Dtzqeq9oK3mhLQcyf7GRIddNK1K3YoZpVAofp138c69A6hxMQdINeeV8Yx2yPEe5LA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219332"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219332/1351_Post_Prostatectomy_Urethral_Hypermobility_Mith_or_Real"><img alt="Research paper thumbnail of 1351 Post Prostatectomy Urethral Hypermobility : Mith or Real?" class="work-thumbnail" src="https://attachments.academia-assets.com/53296895/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219332/1351_Post_Prostatectomy_Urethral_Hypermobility_Mith_or_Real">1351 Post Prostatectomy Urethral Hypermobility : Mith or Real?</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">INTRODUCTION AND OBJECTIVES: Bladder puncture with a trocar is a common intraoperative complicati...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">INTRODUCTION AND OBJECTIVES: Bladder puncture with a trocar is a common intraoperative complication during retropubic midurethral sling (MUS) surgery and is typically treated with trocar repositioning and bladder drainage. However, there is little information regarding the impact of bladder puncture on short-and long-term bladder storage and emptying.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c060c5fcf49dd59a95d6995e9b29b925" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296895,"asset_id":33219332,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296895/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219332"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219332"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219332; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219332]").text(description); $(".js-view-count[data-work-id=33219332]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219332; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219332']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c060c5fcf49dd59a95d6995e9b29b925" } } $('.js-work-strip[data-work-id=33219332]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219332,"title":"1351 Post Prostatectomy Urethral Hypermobility : Mith or Real?","internal_url":"https://www.academia.edu/33219332/1351_Post_Prostatectomy_Urethral_Hypermobility_Mith_or_Real","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296895,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296895/thumbnails/1.jpg","file_name":"j.juro.2012.02.173420170527-12659-1at38ap.pdf","download_url":"https://www.academia.edu/attachments/53296895/download_file","bulk_download_file_name":"1351_Post_Prostatectomy_Urethral_Hypermo.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296895/j.juro.2012.02.173420170527-12659-1at38ap-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3D1351_Post_Prostatectomy_Urethral_Hypermo.pdf\u0026Expires=1740038174\u0026Signature=c8~zE8xAUZFi2D7k5NXHy-~yFQpv9wy1Sj9pMYfbe4a7qRq-rneUdVCge463vuqCszrHp7INzHACVjO0LWxFDCCVaeGaFTasdLoAHxaFpFPCXUZGYiUfXQnlX6PhdqKxTzxnzb3vyMr~sBAFJCHtmCata~S35wk5BtT8zENuA1zZO~Nm7shloGxaJmCOz9QaPfnKe14FXgMxDzX6Yqce2foj6DmwUdy8wUwjpS4vGIEXLzz1ejUd6CeGR6ZXnnVi4TEEpFyMro8ifRHDn3lt~PSkGub672WSsJhnYF76PQM4pNMCmCdzTePF-QJwW58Kc6oCQeKE9Ce6rzcgPi6rIQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219331"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219331/Proposal_of_an_Improved_Prognostic_Classification_for_pT3_Renal_Cell_Carcinoma"><img alt="Research paper thumbnail of Proposal of an Improved Prognostic Classification for pT3 Renal Cell Carcinoma" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219331/Proposal_of_an_Improved_Prognostic_Classification_for_pT3_Renal_Cell_Carcinoma">Proposal of an Improved Prognostic Classification for pT3 Renal Cell Carcinoma</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, 2008</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The prognostic accuracy of the current TNM 2002 staging system for locally advanced renal cell ca...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The prognostic accuracy of the current TNM 2002 staging system for locally advanced renal cell carcinoma has been questioned. To contribute to the development of a more accurate classification for this stage of disease we assessed the correlation between patterns of invasion in the pT3 category and outcomes in a large multi-institutional series. Pathological data and clinical followup on 513 pT3 renal cell carcinoma cases treated with radical nephrectomy between 1983 and 2005 at 3 Italian academic centers were retrospectively reviewed. Cause specific survival rates were calculated with the Kaplan-Meier method and multivariate analysis was performed using the Cox proportional hazards regression model. Estimated overall 5-year cause specific survival was 50.1% at a median followup of 61.5 months in survivors. The current TNM classification was not a significant outcome prognosticator. Patients with a tumor invading only the perirenal or sinus fat were at lowest risk for death from the disease. Patients at intermediate risk had tumors with invasion of the venous system alone. Simultaneous perirenal fat and sinus fat invasion or perirenal fat and vascular invasion as well as adrenal gland involvement characterized high risk tumors. Low risk tumors could be further divided into 2 groups with different outcomes based on a size cutoff of 7 cm. Our classification was a significant predictor of survival on multivariate analysis as well as M stage, N stage, Fuhrman grade and tumor size. We confirm that the prognostic usefulness of the current 2002 TNM system for pT3 renal cell carcinoma is limited. We have identified 4 groups of tumors with distinct patterns of invasion and significantly different survival probabilities in this category. Large prospective series are needed to validate these findings.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219331"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219331"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219331; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219331]").text(description); $(".js-view-count[data-work-id=33219331]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219331; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219331']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219331]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219331,"title":"Proposal of an Improved Prognostic Classification for pT3 Renal Cell Carcinoma","internal_url":"https://www.academia.edu/33219331/Proposal_of_an_Improved_Prognostic_Classification_for_pT3_Renal_Cell_Carcinoma","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219330"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219330/Y_Neobladder_An_Easy_Fast_and_Reliable_Procedure"><img alt="Research paper thumbnail of Y-Neobladder: An Easy, Fast, and Reliable Procedure" class="work-thumbnail" src="https://attachments.academia-assets.com/53296897/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219330/Y_Neobladder_An_Easy_Fast_and_Reliable_Procedure">Y-Neobladder: An Easy, Fast, and Reliable Procedure</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, 2005</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objectives. To describe the operative technique of a new, Y-shaped, ileal neobladder and report t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objectives. To describe the operative technique of a new, Y-shaped, ileal neobladder and report the clinical and functional outcomes to add a contribution to the most discussed issues about orthotopic neobladders, in particular related to the problem of the prevention of strictures of ureteral-neobladder anastomoses. Methods. Between January 1999 and June 2002, 50 patients (41 men and 9 women) underwent radical cystectomy and Y-shaped orthotopic neobladder reconstruction. The following parameters were considered: operative time, complications, and functional outcomes (evaluated with voiding chart and a questionnaire analyzing continence). Urodynamic studies were performed in the first 20 patients. Results. The operative time for neobladder reconstruction was 15 to 20 minutes. No severe complications or significant metabolic complications were recorded. Only 1 case of unilateral stricture of the ureteralneobladder anastomosis was recorded (1% of renal units); the stricture was easily treated with a retrograde endoscopic approach. Daytime and nighttime continence was good or satisfactory in 90% and 85% of patients, respectively. One year after surgery, the average maximal neobladder capacity was 390 mL, and the average pressure at maximal capacity was 15 cm H 2 O. Conclusions. The ileal Y-shaped orthotopic neobladder had good functional outcomes comparable to most popular orthotopic neobladders. Moreover, the surgical technique of the Y-neobladder is easy, rapid, and reliable. In particular, the Y-neobladder seemed to reduce, in our experience, the occurrence of strictures at the ureteral-neobladder anastomosis, because it permits a perfectly aligned anastomosis without mobilization of the ureters.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="9a8f3343b24855e7caa23abc25310f3f" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296897,"asset_id":33219330,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296897/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219330"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219330"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219330; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219330]").text(description); $(".js-view-count[data-work-id=33219330]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219330; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219330']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "9a8f3343b24855e7caa23abc25310f3f" } } $('.js-work-strip[data-work-id=33219330]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219330,"title":"Y-Neobladder: An Easy, Fast, and Reliable Procedure","internal_url":"https://www.academia.edu/33219330/Y_Neobladder_An_Easy_Fast_and_Reliable_Procedure","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296897,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296897/thumbnails/1.jpg","file_name":"Y-neobladder_An_easy_fast_and_reliable_p20170527-12659-1h7mr3k.pdf","download_url":"https://www.academia.edu/attachments/53296897/download_file","bulk_download_file_name":"Y_Neobladder_An_Easy_Fast_and_Reliable_P.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296897/Y-neobladder_An_easy_fast_and_reliable_p20170527-12659-1h7mr3k-libre.pdf?1495898476=\u0026response-content-disposition=attachment%3B+filename%3DY_Neobladder_An_Easy_Fast_and_Reliable_P.pdf\u0026Expires=1740038174\u0026Signature=WiN50ImRVT4hGJr6LLhZrNtHt3vKz16wHvI0-4F1dOeyyFxOdpg0trrfh-YecAa3BTRpoO5iXGgEZM38Y0fzLNAy8oeh2zzXVkLr8y1b3yZPGhORNKFhAjc33w8DryUOX-igF3N4RAwMSiqyhlQ2Bw6TZLw9moPIDJKTDwh9seubhxS1KLS2CG-eNlIeoqwlJ49ujxJvAZ74SXq3v1dM13nFkUo8-dTy4ZSVUcdUOaikJm6VChPDBA0Vwcml94qrbUcf6Rz8bA2hh2vMAjpedcJ5O-GKtGeumo88RgMYiUbHM8CN0jBlETXQc25xt0V5eZ~qJC2q7qhB7ATLCbUcog__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219329"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219329/Study_of_Lymphatic_Drainage_by_SPECT_CT_Fusion_Images_for_Pelvic_Irradiation_of_Prostate_Cancer"><img alt="Research paper thumbnail of Study of Lymphatic Drainage by SPECT-CT Fusion Images for Pelvic Irradiation of Prostate Cancer" class="work-thumbnail" src="https://attachments.academia-assets.com/53296899/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219329/Study_of_Lymphatic_Drainage_by_SPECT_CT_Fusion_Images_for_Pelvic_Irradiation_of_Prostate_Cancer">Study of Lymphatic Drainage by SPECT-CT Fusion Images for Pelvic Irradiation of Prostate Cancer</a></div><div class="wp-workCard_item"><span>International Journal of Radiation Oncology*Biology*Physics</span><span>, 2005</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Purpose/Objective: Several studies suggest the need of pelvic irradiation in patients with high-r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Purpose/Objective: Several studies suggest the need of pelvic irradiation in patients with high-risk of subclinical nodal involvement. Usually, internal and external iliac nodes are included in the treatment volume but no precise information on the pathway of lymphatic drainage is available. The present study aims to investigate the in vivo drainage pathway of lymphatic spread by using lymphoscintigraphy and SPECT-CT fusion to identify the location of the first echelon of potentially involved nodes. Materials/Methods: Fifteen patients with prostate cancer, candidated to surgery and included in a trial studying the sentinel node technique, have been enrolled. Lymphoscintigraphy and SPECT images were obtained 1 and 2-3 hours after intra-prostate trans-rectal injection of 115 MBq of 99mTc-nano-colloid. The first images allowed to identify the first echelon of nodal drainage (sentinel node) and the following images the other pelvic lymph nodes. After the acquisition of SPECT, a spiral CT-scan, with slices of 5 mm thickness was performed. SPECT images were fused with CT images by using external fiducial markers. The volumes of interest were drawn on CT. CTV included prostate, seminal vesicles, and internal and external iliac nodes; bladder and rectum were also delineated. Afterwards, the sentinel node was identified and contoured on SPECT-CT fusion images. The treatment plan using 3D-CRT by 4 fields technique was obtained displaying isodose curves and DVHs for all the delineated structures including sentinel nodes. Results: No patient experienced relevant toxicity related to intra-prostate trans-rectal injection. The sentinel node was identified inside the CTV in all the 15 cases. It was located in external iliac in 60% of cases and in internal iliac nodes in 40%. The sentinel node was identified at the level of the upper third of internal or external iliac nodes in 80% of patients whereas it was located in the central third in 20%. In no case, the sentinel node was found in the lower third of internal or external iliac nodes. The mean dose to the sentinel node was 102.5% (range: 100.2-103.7%) with reference to the ICRU point.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b50bd1993dfec36d5d15a3f3191faf7a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296899,"asset_id":33219329,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296899/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219329"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219329"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219329; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219329]").text(description); $(".js-view-count[data-work-id=33219329]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219329; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219329']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b50bd1993dfec36d5d15a3f3191faf7a" } } $('.js-work-strip[data-work-id=33219329]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219329,"title":"Study of Lymphatic Drainage by SPECT-CT Fusion Images for Pelvic Irradiation of Prostate Cancer","internal_url":"https://www.academia.edu/33219329/Study_of_Lymphatic_Drainage_by_SPECT_CT_Fusion_Images_for_Pelvic_Irradiation_of_Prostate_Cancer","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296899,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296899/thumbnails/1.jpg","file_name":"j.ijrobp.2005.07.52320170527-12656-mpf0fr.pdf","download_url":"https://www.academia.edu/attachments/53296899/download_file","bulk_download_file_name":"Study_of_Lymphatic_Drainage_by_SPECT_CT.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296899/j.ijrobp.2005.07.52320170527-12656-mpf0fr-libre.pdf?1495898474=\u0026response-content-disposition=attachment%3B+filename%3DStudy_of_Lymphatic_Drainage_by_SPECT_CT.pdf\u0026Expires=1740038174\u0026Signature=VcfKW8B0SAeipeCIGgZhB-x8kuNAhqhjydsDrrd3IBLBn0vNQYFlfcNXic3BUjcWXnJZEbL1T~RHPt70CYdDm0umwT2fvruOAl4GouvS3QTiFVDTkuGGpNGCpGamBhUNvqxY62UxJYyIG3Qoyu2SrOwzC-imfM9i-RoLkzaI3iNRJ~bbcT~ep743VJMMcHOZnH063zq0yYHbOM02JnTHAyocWdt2BSc3Oln8iw7MpRcY4RNJj3oAnV~HpeY8sKYoPJSdxfBXFCuJEg~Nh3kTFeNdQHQm0N2XLwcSLmrj1nXWoGKiB5zpyljKzCfwp8LC5cSz84r937m8EHTX3Zo-Nw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219326"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219326/A_Single_center_Analysis_on_the_Learning_Curve_of_Male_to_Female_Penoscrotal_Vaginoplasty_by_Multiple_Surgical_Measures"><img alt="Research paper thumbnail of A Single-center Analysis on the Learning Curve of Male-to-Female Penoscrotal Vaginoplasty by Multiple Surgical Measures" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219326/A_Single_center_Analysis_on_the_Learning_Curve_of_Male_to_Female_Penoscrotal_Vaginoplasty_by_Multiple_Surgical_Measures">A Single-center Analysis on the Learning Curve of Male-to-Female Penoscrotal Vaginoplasty by Multiple Surgical Measures</a></div><div class="wp-workCard_item"><span>Urology</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To asses and quantify the learning curve (LC) of the penoscrotal inversion flap vaginoplasty (PSV...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To asses and quantify the learning curve (LC) of the penoscrotal inversion flap vaginoplasty (PSV). We retrospectively reviewed clinical records of 69 patients who underwent PSV from January 2005 to January 2015. Two validated methods were used: a scatterplot representation and a splitting group. We selected as primary outcomes the operative time and vaginal depth. Surgical outcomes including blood losses, hospital stay, and postoperative complications such as vaginal stenosis or atresia or urethral meatus stenosis were also evaluated. The overall median operative time was 245 minutes. Severe intraoperative complications were not reported. The overall incidence of postoperative major complications was 21.7 %, most of them being urethral issues. The splitting group analysis revealed a statistically remarkable difference between groups for the operative time (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .01), the vaginal depth (P = .01), the hospital stay (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .01), and the intraoperative complication rate (P = .01). On the contrary, no differences were evidenced between the cohorts for the amount of blood loss (P = .08). The scatterplot logarithmic analysis demonstrated a clear visible LC for most parameters. The operative time showed a sharp decrease within the first 20-30 cases, reaching a plateau after 40 cases. Considering the analysis of the vaginal depth, the logarithmic scatterplot curve evidenced a slight increase within the first 10 cases, reaching a clear stabilization after nearly 30-40 cases. An evident LC for PSV is detectable, consisting of at least 40 cases needed to the surgical team to develop adequate skills to guarantee a safe and high-quality procedure.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219326"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219326"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219326; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219326]").text(description); $(".js-view-count[data-work-id=33219326]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219326; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219326']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219326]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219326,"title":"A Single-center Analysis on the Learning Curve of Male-to-Female Penoscrotal Vaginoplasty by Multiple Surgical Measures","internal_url":"https://www.academia.edu/33219326/A_Single_center_Analysis_on_the_Learning_Curve_of_Male_to_Female_Penoscrotal_Vaginoplasty_by_Multiple_Surgical_Measures","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219325"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219325/POD_11_06_Use_of_the_adjustable_continence_therapy_for_post_prostatatectomy_urodynamic_stress_urinary_incontinence"><img alt="Research paper thumbnail of POD-11.06: Use of the adjustable continence therapy for post prostatatectomy urodynamic stress urinary incontinence" class="work-thumbnail" src="https://attachments.academia-assets.com/53296894/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219325/POD_11_06_Use_of_the_adjustable_continence_therapy_for_post_prostatatectomy_urodynamic_stress_urinary_incontinence">POD-11.06: Use of the adjustable continence therapy for post prostatatectomy urodynamic stress urinary incontinence</a></div><div class="wp-workCard_item"><span>Urology</span><span>, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">2/10 became dry, 6 improved (one underwear liner) and 2 were unchanged. Eleven patients had previ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">2/10 became dry, 6 improved (one underwear liner) and 2 were unchanged. Eleven patients had previously undergone external beam radiotherapy prior to balloon implantation. Four (33.3%) were dry following adjustment, 2(24%) were improved and 5/11 (42.7%) were unchanged at last follow up. 4 reports of denovo urge had resolution of symptoms following anticholinergic therapy within one month of surgery.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="87a9456400057f16e70a7f75dae2b684" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296894,"asset_id":33219325,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296894/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219325"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219325"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219325; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219325]").text(description); $(".js-view-count[data-work-id=33219325]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219325; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219325']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "87a9456400057f16e70a7f75dae2b684" } } $('.js-work-strip[data-work-id=33219325]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219325,"title":"POD-11.06: Use of the adjustable continence therapy for post prostatatectomy urodynamic stress urinary incontinence","internal_url":"https://www.academia.edu/33219325/POD_11_06_Use_of_the_adjustable_continence_therapy_for_post_prostatatectomy_urodynamic_stress_urinary_incontinence","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296894,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296894/thumbnails/1.jpg","file_name":"j.urology.2007.06.15220170527-12653-ihd0he.pdf","download_url":"https://www.academia.edu/attachments/53296894/download_file","bulk_download_file_name":"POD_11_06_Use_of_the_adjustable_continen.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296894/j.urology.2007.06.15220170527-12653-ihd0he-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3DPOD_11_06_Use_of_the_adjustable_continen.pdf\u0026Expires=1740038174\u0026Signature=IHqGqas3AHLrLGIRyxZksHolq-5whr5rz9OlPNdq6yiI1l~hb7V-8yCuda6GsckkjsB1NzmLvoD3xc34gAVDWz~C3n3PSeN3foiB9bIIQ11bS8aCkmx7m0LQyqkEjOiRGz6lH6Tlxp9v0Bd5LikBytzhAY34s~OHd3njgscbx-gEw-48EqL-cWsOI2-nsIjZgLw5SkWZiwvFPJTuWB0qNFjTflo0DGMe5c-sj9SgfdQncS6QUE~3l68RMzU5m2HSUywKvEXaxHYCv0qXyvEvjHVVLvWuvnWxQMUG5q07vL2tr5cvz3J0uqNPh~FaymcKrFmrkzpKtAD~QLvsMPlS8A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219324"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219324/361Sexual_disorders_in_hemodialysed_female_patients"><img alt="Research paper thumbnail of 361Sexual disorders in hemodialysed female patients" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219324/361Sexual_disorders_in_hemodialysed_female_patients">361Sexual disorders in hemodialysed female patients</a></div><div class="wp-workCard_item"><span>Eur Urol Suppl</span><span>, 2005</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219324"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219324"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219324; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219324]").text(description); $(".js-view-count[data-work-id=33219324]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219324; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219324']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219324]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219324,"title":"361Sexual disorders in hemodialysed female patients","internal_url":"https://www.academia.edu/33219324/361Sexual_disorders_in_hemodialysed_female_patients","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219323"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219323/Is_There_an_Optimal_Time_for_Intracavernous_Prostaglandin_E1_Rehabilitation_Following_Nonnerve_Sparing_Radical_Prostatectomy_Results_From_a_Hemodynamic_Prospective_Study"><img alt="Research paper thumbnail of Is There an Optimal Time for Intracavernous Prostaglandin E1 Rehabilitation Following Nonnerve Sparing Radical Prostatectomy? Results From a Hemodynamic Prospective Study" class="work-thumbnail" src="https://attachments.academia-assets.com/53296891/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219323/Is_There_an_Optimal_Time_for_Intracavernous_Prostaglandin_E1_Rehabilitation_Following_Nonnerve_Sparing_Radical_Prostatectomy_Results_From_a_Hemodynamic_Prospective_Study">Is There an Optimal Time for Intracavernous Prostaglandin E1 Rehabilitation Following Nonnerve Sparing Radical Prostatectomy? Results From a Hemodynamic Prospective Study</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, Jun 1, 2003</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Purpose: Previous studies have shown that early intracavernous prostaglandin E1 injection may red...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Purpose: Previous studies have shown that early intracavernous prostaglandin E1 injection may reduce significantly the incidence of veno-occlusive dysfunction before spontaneous erections recover after nerve sparing radical prostatectomy. We identify the more convenient postoperative timing for successful intracavernous injection rehabilitation in a series of patients who underwent nonnerve sparing radical prostatectomy.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f6d9bfb40fd757ae5bfb5404864f712a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296891,"asset_id":33219323,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296891/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219323"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219323"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219323; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219323]").text(description); $(".js-view-count[data-work-id=33219323]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219323; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219323']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f6d9bfb40fd757ae5bfb5404864f712a" } } $('.js-work-strip[data-work-id=33219323]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219323,"title":"Is There an Optimal Time for Intracavernous Prostaglandin E1 Rehabilitation Following Nonnerve Sparing Radical Prostatectomy? Results From a Hemodynamic Prospective Study","internal_url":"https://www.academia.edu/33219323/Is_There_an_Optimal_Time_for_Intracavernous_Prostaglandin_E1_Rehabilitation_Following_Nonnerve_Sparing_Radical_Prostatectomy_Results_From_a_Hemodynamic_Prospective_Study","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296891,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296891/thumbnails/1.jpg","file_name":"01.ju.0000064939.04658.1520170527-12653-1k1j7i6.pdf","download_url":"https://www.academia.edu/attachments/53296891/download_file","bulk_download_file_name":"Is_There_an_Optimal_Time_for_Intracavern.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296891/01.ju.0000064939.04658.1520170527-12653-1k1j7i6-libre.pdf?1495898475=\u0026response-content-disposition=attachment%3B+filename%3DIs_There_an_Optimal_Time_for_Intracavern.pdf\u0026Expires=1740038174\u0026Signature=a5f2B0AySiPLFnIdei2XJlrez36s6QowHN0SSzxqKhyGF563x5EwzwvQ8OfVbA6qiJbipF-cuwqeG3pjIy8S7fezCgdi3sxfSwL5SUPs4DMB~WyVP3fhtJhiBCRH7Mz4F9oGC3CTQI3tztUb98JmKuUIuf5iZ~yDV491CxlNQiZfidaJrpGsJuW0XmfVrEPtnhlzYUiVVCKyK4j6x2UlC4k5oumNV409HMk9MWS3s3MaKoQ2yFNHtFX3f3NSIBo05hQMMO~gByIMG63-LG-Tdi-MSuPi8fVPPijJTkLGLMwyvUJzyHvYyj13IMV2~pgR4Rai9r8bitzodiuMCRDU7g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219322"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219322/Sentinel_lymph_node_detection_during_radical_prostatectomy_for_prostate_cancer_current_evidence_and_results_of_our_experience"><img alt="Research paper thumbnail of Sentinel lymph node detection during radical prostatectomy for prostate cancer: current evidence and results of our experience" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219322/Sentinel_lymph_node_detection_during_radical_prostatectomy_for_prostate_cancer_current_evidence_and_results_of_our_experience">Sentinel lymph node detection during radical prostatectomy for prostate cancer: current evidence and results of our experience</a></div><div class="wp-workCard_item"><span>Urologia</span><span>, Jan 21, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A sentinel lymph node (SNL) is the primary landing zone of cancer cells that spreads through the ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A sentinel lymph node (SNL) is the primary landing zone of cancer cells that spreads through the lymphatic vessels. The rational of the detection of sentinel node (SLN) during radical prostatectomy (RP) for prostate cancer (PCa) is the removal of the first nodal stations to provide a restriction of the template of node dissection. A review of the outcomes of SNL detection during RP for PCa was performed. A systematic review of the literature was conducted, searching on PubMed and Web of Science, using the following keywords: lymph node dissection, prostatic neoplasm, sentinel node. Twenty articles were selected and analyzed including over 2000 PCa patients. Although promising and technically feasible, many points remain to be clarified before clinical application can be recommended. The technique of SNL detection is feasible and provides a higher sensitivity and detection rate than standard lymphadenectomy, especially for organ-confined tumors. Larger series and long-term follow-up ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219322"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219322"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219322; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219322]").text(description); $(".js-view-count[data-work-id=33219322]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219322; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219322']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219322]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219322,"title":"Sentinel lymph node detection during radical prostatectomy for prostate cancer: current evidence and results of our experience","internal_url":"https://www.academia.edu/33219322/Sentinel_lymph_node_detection_during_radical_prostatectomy_for_prostate_cancer_current_evidence_and_results_of_our_experience","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219321"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33219321/Metastasis_Markers_in_Bladder_Cancer_A_Review_of_the_Literature_and_Clinical_Considerations"><img alt="Research paper thumbnail of Metastasis Markers in Bladder Cancer: A Review of the Literature and Clinical Considerations" class="work-thumbnail" src="https://attachments.academia-assets.com/53296893/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33219321/Metastasis_Markers_in_Bladder_Cancer_A_Review_of_the_Literature_and_Clinical_Considerations">Metastasis Markers in Bladder Cancer: A Review of the Literature and Clinical Considerations</a></div><div class="wp-workCard_item"><span>European Urology</span><span>, Sep 30, 2004</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Cancer invasion and metastasis develop through a sequence of processes involving loss of cell-cel...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Cancer invasion and metastasis develop through a sequence of processes involving loss of cell-cell and cell-matrix adhesions, proteolysis and induction of angiogenesis. We reviewed the current literature on the molecules that have been shown to play a significant role in these three steps of metastatisation in bladder cancer (BC) cells and their host microenvironment. Particular emphasis was given to markers that are assessable through immunohistochemistry and for which an additional prognostic value over the TNM variables has been recognized, in order to identify a subset of tumour markers readily available for application in daily clinical practice.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="85d8c6b3be162b0a54a0a4427d5e04ce" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53296893,"asset_id":33219321,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53296893/download_file?s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219321"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219321"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219321; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219321]").text(description); $(".js-view-count[data-work-id=33219321]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219321; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219321']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "85d8c6b3be162b0a54a0a4427d5e04ce" } } $('.js-work-strip[data-work-id=33219321]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219321,"title":"Metastasis Markers in Bladder Cancer: A Review of the Literature and Clinical Considerations","internal_url":"https://www.academia.edu/33219321/Metastasis_Markers_in_Bladder_Cancer_A_Review_of_the_Literature_and_Clinical_Considerations","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[{"id":53296893,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/53296893/thumbnails/1.jpg","file_name":"j.eururo.2004.04.00120170527-12659-zcdua4.pdf","download_url":"https://www.academia.edu/attachments/53296893/download_file","bulk_download_file_name":"Metastasis_Markers_in_Bladder_Cancer_A_R.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/53296893/j.eururo.2004.04.00120170527-12659-zcdua4-libre.pdf?1495898477=\u0026response-content-disposition=attachment%3B+filename%3DMetastasis_Markers_in_Bladder_Cancer_A_R.pdf\u0026Expires=1740038174\u0026Signature=TcRy-dMg7~aga6QJFgb44cYGsO3P7-PFu7SV6R2mx~TvdE2VSiOo7HaPcLJbwHXKgdFcm2MW3n33jP0PH-ZEPxl2mujhEHtj3TdjXBODaJf8cw~RFMWN0YgivvhpiQ5TqK8gjSI2XTrtMcnZ6EMzI7w~FlNWITLEWhUpQtz2E~oTOwy8N3d~zYexvcgDXZGJGC5mBZNgtI27WN2cx1gUWea6Fd5FM1SdHYw-6DVKxn747YwPe30ou1JA9ljoa1ieT7RoewZcuupyCenXzx6MOWBtxYfQUnLHeDrByYc2zDXY0zIfIX8BLVZTaHTvG6gxy0n7wCH0mB525j5ZZo~LeA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219320"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219320/New_Insights_Into_the_Pathogenesis_of_Penile_Shortening_After_Radical_Prostatectomy_and_the_Role_of_Postoperative_Sexual_Function"><img alt="Research paper thumbnail of New Insights Into the Pathogenesis of Penile Shortening After Radical Prostatectomy and the Role of Postoperative Sexual Function" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219320/New_Insights_Into_the_Pathogenesis_of_Penile_Shortening_After_Radical_Prostatectomy_and_the_Role_of_Postoperative_Sexual_Function">New Insights Into the Pathogenesis of Penile Shortening After Radical Prostatectomy and the Role of Postoperative Sexual Function</a></div><div class="wp-workCard_item"><span>The Journal of Urology</span><span>, Aug 1, 2007</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">PURPOSE: We assessed penile changes after radical prostatectomy by performing serial penile measu...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">PURPOSE: We assessed penile changes after radical prostatectomy by performing serial penile measurements. The potential effect of nerve sparing surgery and the recovery of erectile function on the degree of penile shortening were also evaluated.MATERIALS AND METHODS: A total of 126 consecutive patients were enrolled. Penile measurements were taken immediately before surgery, at catheter removal, and at 3, 6 and 12 months postoperatively. Sexual function was assessed at baseline and at 3, 6 and 12 months using the erectile function domain of the International Index of Erectile Function.RESULTS: The maximum degree of shortening was noted at the time of catheter removal (mean 0.84 cm, CI 0.62-1.06, p <0.0001 for stretched penis). All penile parameters showed a lesser but significant decrease at all subsequent intervals. Univariate analysis revealed that baseline penile length was the only variable significantly associated with stretched penile length at catheter removal. Age, nerve sparing surgery and the recovery of erectile function were strong predictors of penile size 1 year after surgery. Multivariate analysis showed that nerve sparing surgery (<0.0001) and the recovery of erectile function (p = 0.053) were independent predictors of the final changes in penile size.CONCLUSIONS: Penile shortening after radical prostatectomy peaks at the time of catheter removal and it continues to a lesser but still significant degree for at least 1 year. Nerve sparing surgery and recovery of erectile function appeared to have an independent protective effect on penile length loss at 1 year. These figures should be taken in consideration when counseling patients for radical prostatectomy.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219320"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219320"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219320; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219320]").text(description); $(".js-view-count[data-work-id=33219320]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219320; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219320']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219320]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219320,"title":"New Insights Into the Pathogenesis of Penile Shortening After Radical Prostatectomy and the Role of Postoperative Sexual Function","internal_url":"https://www.academia.edu/33219320/New_Insights_Into_the_Pathogenesis_of_Penile_Shortening_After_Radical_Prostatectomy_and_the_Role_of_Postoperative_Sexual_Function","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33219319"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/33219319/Can_MRI_Predict_Which_Patients_Are_Most_Likely_to_Benefi_t_from_Percutaneous_Positioning_of_Volume_Adjustable_Balloon_Devices"><img alt="Research paper thumbnail of Can MRI Predict Which Patients Are Most Likely to Benefi t from Percutaneous Positioning of Volume-Adjustable Balloon Devices?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/33219319/Can_MRI_Predict_Which_Patients_Are_Most_Likely_to_Benefi_t_from_Percutaneous_Positioning_of_Volume_Adjustable_Balloon_Devices">Can MRI Predict Which Patients Are Most Likely to Benefi t from Percutaneous Positioning of Volume-Adjustable Balloon Devices?</a></div><div class="wp-workCard_item"><span>Urol Int</span><span>, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To assess whether magnetic resonance imaging (MRI) is useful in predicting which patients affecte...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To assess whether magnetic resonance imaging (MRI) is useful in predicting which patients affected by stress urinary incontinence (SUI) will benefit from a new anti-incontinence therapy named adjustable continence therapy (AC). We prospectively evaluated a group of 25 female patients affected by SUI and treated with ACT. Before and after treatment all patients were clinically assessed by physical examination, urodynamic evaluation and pad test. All patients had an MR examination before and 3 and 12 months after ACT surgery to compare the position of the bladder neck in relation to the pubococcygeal line (PCL). 21/25 (84%) patients were improved; 16 (64%) of these patients were dry and 5 (20%) significantly improved. Before treatment, the mean PCL distance was significantly different (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;0.01) between the responsive and the non-responsive groups. MRI provides an effective radiological method to predict the efficacy of the ACT.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33219319"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33219319"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33219319; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33219319]").text(description); $(".js-view-count[data-work-id=33219319]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33219319; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33219319']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=33219319]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33219319,"title":"Can MRI Predict Which Patients Are Most Likely to Benefi t from Percutaneous Positioning of Volume-Adjustable Balloon Devices?","internal_url":"https://www.academia.edu/33219319/Can_MRI_Predict_Which_Patients_Are_Most_Likely_to_Benefi_t_from_Percutaneous_Positioning_of_Volume_Adjustable_Balloon_Devices","owner_id":64819573,"coauthors_can_edit":true,"owner":{"id":64819573,"first_name":"Bruno","middle_initials":"","last_name":"Frea","page_name":"BrunoFrea","domain_name":"independent","created_at":"2017-05-27T08:14:52.852-07:00","display_name":"Bruno Frea","url":"https://independent.academia.edu/BrunoFrea"},"attachments":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js","https://a.academia-assets.com/assets/google_contacts-0dfb882d836b94dbcb4a2d123d6933fc9533eda5be911641f20b4eb428429600.js"], function() { // from javascript_helper.rb $('.js-google-connect-button').click(function(e) { e.preventDefault(); GoogleContacts.authorize_and_show_contacts(); Aedu.Dismissibles.recordClickthrough("WowProfileImportContactsPrompt"); }); $('.js-update-biography-button').click(function(e) { e.preventDefault(); Aedu.Dismissibles.recordClickthrough("UpdateUserBiographyPrompt"); $.ajax({ url: $r.api_v0_profiles_update_about_path({ subdomain_param: 'api', about: "", }), type: 'PUT', success: function(response) { location.reload(); } }); }); $('.js-work-creator-button').click(function (e) { e.preventDefault(); window.location = $r.upload_funnel_document_path({ source: encodeURIComponent(""), }); }); $('.js-video-upload-button').click(function (e) { e.preventDefault(); window.location = $r.upload_funnel_video_path({ source: encodeURIComponent(""), }); }); $('.js-do-this-later-button').click(function() { $(this).closest('.js-profile-nag-panel').remove(); Aedu.Dismissibles.recordDismissal("WowProfileImportContactsPrompt"); }); $('.js-update-biography-do-this-later-button').click(function(){ $(this).closest('.js-profile-nag-panel').remove(); Aedu.Dismissibles.recordDismissal("UpdateUserBiographyPrompt"); }); $('.wow-profile-mentions-upsell--close').click(function(){ $('.wow-profile-mentions-upsell--panel').hide(); Aedu.Dismissibles.recordDismissal("WowProfileMentionsUpsell"); }); $('.wow-profile-mentions-upsell--button').click(function(){ Aedu.Dismissibles.recordClickthrough("WowProfileMentionsUpsell"); }); new WowProfile.SocialRedesignUserWorks({ initialWorksOffset: 20, allWorksOffset: 20, maxSections: 1 }) }); </script> </div></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile_edit-5ea339ee107c863779f560dd7275595239fed73f1a13d279d2b599a28c0ecd33.js","https://a.academia-assets.com/assets/add_coauthor-22174b608f9cb871d03443cafa7feac496fb50d7df2d66a53f5ee3c04ba67f53.js","https://a.academia-assets.com/assets/tab-dcac0130902f0cc2d8cb403714dd47454f11fc6fb0e99ae6a0827b06613abc20.js","https://a.academia-assets.com/assets/wow_profile-a9bf3a2bc8c89fa2a77156577594264ee8a0f214d74241bc0fcd3f69f8d107ac.js"], function() { // from javascript_helper.rb window.ae = window.ae || {}; window.ae.WowProfile = window.ae.WowProfile || {}; if(Aedu.User.current && Aedu.User.current.id === $viewedUser.id) { window.ae.WowProfile.current_user_edit = {}; new WowProfileEdit.EditUploadView({ el: '.js-edit-upload-button-wrapper', model: window.$current_user, }); new AddCoauthor.AddCoauthorsController(); } var userInfoView = new WowProfile.SocialRedesignUserInfo({ recaptcha_key: "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB" }); WowProfile.router = new WowProfile.Router({ userInfoView: userInfoView }); Backbone.history.start({ pushState: true, root: "/" + $viewedUser.page_name }); new WowProfile.UserWorksNav() }); </script> </div> <div class="bootstrap login"><div class="modal fade login-modal" id="login-modal"><div class="login-modal-dialog modal-dialog"><div class="modal-content"><div class="modal-header"><button class="close close" data-dismiss="modal" type="button"><span aria-hidden="true">×</span><span class="sr-only">Close</span></button><h4 class="modal-title text-center"><strong>Log In</strong></h4></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><button class="btn btn-fb btn-lg btn-block btn-v-center-content" id="login-facebook-oauth-button"><svg style="float: left; width: 19px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="facebook-square" class="svg-inline--fa fa-facebook-square fa-w-14" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path fill="currentColor" d="M400 32H48A48 48 0 0 0 0 80v352a48 48 0 0 0 48 48h137.25V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.27c-30.81 0-40.42 19.12-40.42 38.73V256h68.78l-11 71.69h-57.78V480H400a48 48 0 0 0 48-48V80a48 48 0 0 0-48-48z"></path></svg><small><strong>Log in</strong> with <strong>Facebook</strong></small></button><br /><button class="btn btn-google btn-lg btn-block btn-v-center-content" id="login-google-oauth-button"><svg style="float: left; width: 22px; line-height: 1em; margin-right: .3em;" aria-hidden="true" focusable="false" data-prefix="fab" data-icon="google-plus" class="svg-inline--fa fa-google-plus fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M256,8C119.1,8,8,119.1,8,256S119.1,504,256,504,504,392.9,504,256,392.9,8,256,8ZM185.3,380a124,124,0,0,1,0-248c31.3,0,60.1,11,83,32.3l-33.6,32.6c-13.2-12.9-31.3-19.1-49.4-19.1-42.9,0-77.2,35.5-77.2,78.1S142.3,334,185.3,334c32.6,0,64.9-19.1,70.1-53.3H185.3V238.1H302.2a109.2,109.2,0,0,1,1.9,20.7c0,70.8-47.5,121.2-118.8,121.2ZM415.5,273.8v35.5H380V273.8H344.5V238.3H380V202.8h35.5v35.5h35.2v35.5Z"></path></svg><small><strong>Log in</strong> with <strong>Google</strong></small></button><br /><style type="text/css">.sign-in-with-apple-button { width: 100%; height: 52px; border-radius: 3px; border: 1px solid black; cursor: pointer; } .sign-in-with-apple-button > div { margin: 0 auto; / This centers the Apple-rendered button horizontally }</style><script src="https://appleid.cdn-apple.com/appleauth/static/jsapi/appleid/1/en_US/appleid.auth.js" type="text/javascript"></script><div class="sign-in-with-apple-button" data-border="false" data-color="white" id="appleid-signin"><span   ="Sign Up with Apple" class="u-fs11"></span></div><script>AppleID.auth.init({ clientId: 'edu.academia.applesignon', scope: 'name email', redirectURI: 'https://www.academia.edu/sessions', state: "bf4bd254ee3d4fb5485fc3e02e7e62d072328cc0cf2dc010bd31d43e76ffebd6", });</script><script>// Hacky way of checking if on fast loswp if (window.loswp == null) { (function() { const Google = window?.Aedu?.Auth?.OauthButton?.Login?.Google; const Facebook = window?.Aedu?.Auth?.OauthButton?.Login?.Facebook; if (Google) { new Google({ el: '#login-google-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } if (Facebook) { new Facebook({ el: '#login-facebook-oauth-button', rememberMeCheckboxId: 'remember_me', track: null }); } })(); }</script></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><div class="hr-heading login-hr-heading"><span class="hr-heading-text">or</span></div></div></div></div><div class="modal-body"><div class="row"><div class="col-xs-10 col-xs-offset-1"><form class="js-login-form" action="https://www.academia.edu/sessions" accept-charset="UTF-8" method="post"><input type="hidden" name="authenticity_token" value="S_nlWC7Ov3v7E4TiGUMUJd0v8ygywJpGbZO-9AdgWc2-D2fU813A9SLh5J8MOs0yMG0xo4jo-1OCBrjQCM2sMQ" autocomplete="off" /><div class="form-group"><label class="control-label" for="login-modal-email-input" style="font-size: 14px;">Email</label><input class="form-control" id="login-modal-email-input" name="login" type="email" /></div><div class="form-group"><label class="control-label" for="login-modal-password-input" style="font-size: 14px;">Password</label><input class="form-control" id="login-modal-password-input" name="password" type="password" /></div><input type="hidden" name="post_login_redirect_url" id="post_login_redirect_url" value="https://independent.academia.edu/BrunoFrea" autocomplete="off" /><div class="checkbox"><label><input type="checkbox" name="remember_me" id="remember_me" value="1" checked="checked" /><small style="font-size: 12px; margin-top: 2px; display: inline-block;">Remember me on this computer</small></label></div><br><input type="submit" name="commit" value="Log In" class="btn btn-primary btn-block btn-lg js-login-submit" data-disable-with="Log In" /></br></form><script>typeof window?.Aedu?.recaptchaManagedForm === 'function' && window.Aedu.recaptchaManagedForm( document.querySelector('.js-login-form'), document.querySelector('.js-login-submit') );</script><small style="font-size: 12px;"><br />or <a data-target="#login-modal-reset-password-container" data-toggle="collapse" href="javascript:void(0)">reset password</a></small><div class="collapse" id="login-modal-reset-password-container"><br /><div class="well margin-0x"><form class="js-password-reset-form" action="https://www.academia.edu/reset_password" accept-charset="UTF-8" method="post"><input type="hidden" name="authenticity_token" value="LsXFeugiE1fFCUS_f4yFoETyDfmpMeyIEs90lEEEu5fbM0f2NbFs2Rz7JMJq9Vy3qbDPchMZjZ39WnKwTqlOaw" autocomplete="off" /><p>Enter the email address you signed up with and we'll email you a reset link.</p><div class="form-group"><input class="form-control" name="email" type="email" /></div><script src="https://recaptcha.net/recaptcha/api.js" async defer></script> <script> var invisibleRecaptchaSubmit = function () { var closestForm = function (ele) { var curEle = ele.parentNode; while (curEle.nodeName !== 'FORM' && curEle.nodeName !== 'BODY'){ curEle = curEle.parentNode; } return curEle.nodeName === 'FORM' ? curEle : null }; var eles = document.getElementsByClassName('g-recaptcha'); if (eles.length > 0) { var form = closestForm(eles[0]); if (form) { form.submit(); } } }; </script> <input type="submit" data-sitekey="6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj" data-callback="invisibleRecaptchaSubmit" class="g-recaptcha btn btn-primary btn-block" value="Email me a link" value=""/> </form></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/collapse-45805421cf446ca5adf7aaa1935b08a3a8d1d9a6cc5d91a62a2a3a00b20b3e6a.js"], function() { // from javascript_helper.rb $("#login-modal-reset-password-container").on("shown.bs.collapse", function() { $(this).find("input[type=email]").focus(); }); }); </script> </div></div></div><div class="modal-footer"><div class="text-center"><small style="font-size: 12px;">Need an account? <a rel="nofollow" href="https://www.academia.edu/signup">Click here to sign up</a></small></div></div></div></div></div></div><script>// If we are on subdomain or non-bootstrapped page, redirect to login page instead of showing modal (function(){ if (typeof $ === 'undefined') return; var host = window.location.hostname; if ((host === $domain || host === "www."+$domain) && (typeof $().modal === 'function')) { $("#nav_log_in").click(function(e) { // Don't follow the link and open the modal e.preventDefault(); $("#login-modal").on('shown.bs.modal', function() { $(this).find("#login-modal-email-input").focus() }).modal('show'); }); } })()</script> <div class="bootstrap" id="footer"><div class="footer-content clearfix text-center padding-top-7x" style="width:100%;"><ul class="footer-links-secondary footer-links-wide list-inline margin-bottom-1x"><li><a href="https://www.academia.edu/about">About</a></li><li><a href="https://www.academia.edu/press">Press</a></li><li><a href="https://www.academia.edu/documents">Papers</a></li><li><a href="https://www.academia.edu/topics">Topics</a></li><li><a href="https://www.academia.edu/journals">Academia.edu Journals</a></li><li><a rel="nofollow" href="https://www.academia.edu/hiring"><svg style="width: 13px; height: 13px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="briefcase" class="svg-inline--fa fa-briefcase fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M320 336c0 8.84-7.16 16-16 16h-96c-8.84 0-16-7.16-16-16v-48H0v144c0 25.6 22.4 48 48 48h416c25.6 0 48-22.4 48-48V288H320v48zm144-208h-80V80c0-25.6-22.4-48-48-48H176c-25.6 0-48 22.4-48 48v48H48c-25.6 0-48 22.4-48 48v80h512v-80c0-25.6-22.4-48-48-48zm-144 0H192V96h128v32z"></path></svg> <strong>We're Hiring!</strong></a></li><li><a rel="nofollow" href="https://support.academia.edu/hc/en-us"><svg style="width: 12px; height: 12px;" aria-hidden="true" focusable="false" data-prefix="fas" data-icon="question-circle" class="svg-inline--fa fa-question-circle fa-w-16" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M504 256c0 136.997-111.043 248-248 248S8 392.997 8 256C8 119.083 119.043 8 256 8s248 111.083 248 248zM262.655 90c-54.497 0-89.255 22.957-116.549 63.758-3.536 5.286-2.353 12.415 2.715 16.258l34.699 26.31c5.205 3.947 12.621 3.008 16.665-2.122 17.864-22.658 30.113-35.797 57.303-35.797 20.429 0 45.698 13.148 45.698 32.958 0 14.976-12.363 22.667-32.534 33.976C247.128 238.528 216 254.941 216 296v4c0 6.627 5.373 12 12 12h56c6.627 0 12-5.373 12-12v-1.333c0-28.462 83.186-29.647 83.186-106.667 0-58.002-60.165-102-116.531-102zM256 338c-25.365 0-46 20.635-46 46 0 25.364 20.635 46 46 46s46-20.636 46-46c0-25.365-20.635-46-46-46z"></path></svg> <strong>Help Center</strong></a></li></ul><ul class="footer-links-tertiary list-inline margin-bottom-1x"><li class="small">Find new research papers in:</li><li class="small"><a href="https://www.academia.edu/Documents/in/Physics">Physics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Biology">Biology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Health_Sciences">Health Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Ecology">Ecology</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Earth_Sciences">Earth Sciences</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Cognitive_Science">Cognitive Science</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Mathematics">Mathematics</a></li><li class="small"><a href="https://www.academia.edu/Documents/in/Computer_Science">Computer Science</a></li></ul></div></div><div class="DesignSystem" id="credit" style="width:100%;"><ul class="u-pl0x footer-links-legal list-inline"><li><a rel="nofollow" href="https://www.academia.edu/terms">Terms</a></li><li><a rel="nofollow" href="https://www.academia.edu/privacy">Privacy</a></li><li><a rel="nofollow" href="https://www.academia.edu/copyright">Copyright</a></li><li>Academia ©2025</li></ul></div><script> //<![CDATA[ window.detect_gmtoffset = true; window.Academia && window.Academia.set_gmtoffset && Academia.set_gmtoffset('/gmtoffset'); //]]> </script> <div id='overlay_background'></div> <div id='bootstrap-modal-container' class='bootstrap'></div> <div id='ds-modal-container' class='bootstrap DesignSystem'></div> <div id='full-screen-modal'></div> </div> </body> </html>