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<div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="Aspetto"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="Modifica la dimensione, la larghezza e il colore del testo" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="Aspetto" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">Aspetto</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_it.wikipedia.org&uselang=it" class=""><span>Fai una donazione</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Speciale:CreaUtenza&returnto=Assoplasma" title="Si consiglia di registrarsi e di effettuare l'accesso, anche se non è obbligatorio" class=""><span>registrati</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Speciale:Entra&returnto=Assoplasma" title="Si consiglia di effettuare l'accesso, anche se non è obbligatorio [o]" accesskey="o" class=""><span>entra</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Altre opzioni" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" 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href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_it.wikipedia.org&uselang=it"><span>Fai una donazione</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Speciale:CreaUtenza&returnto=Assoplasma" title="Si consiglia di registrarsi e di effettuare l'accesso, anche se non è obbligatorio"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>registrati</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Speciale:Entra&returnto=Assoplasma" title="Si consiglia di effettuare l'accesso, anche se non è obbligatorio [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>entra</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Pagine per utenti anonimi <a href="/wiki/Aiuto:Benvenuto" aria-label="Ulteriori informazioni sulla contribuzione"><span>ulteriori informazioni</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Speciale:MieiContributi" title="Un elenco delle modifiche fatte da questo indirizzo IP [y]" accesskey="y"><span>contributi</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Speciale:MieDiscussioni" title="Discussioni sulle modifiche fatte da questo indirizzo IP [n]" accesskey="n"><span>discussioni</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Sito"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Indice" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Indice</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">sposta nella barra laterale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">nascondi</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Inizio</div> </a> </li> <li id="toc-Struttura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Struttura"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Struttura</span> </div> </a> <ul id="toc-Struttura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Funzione" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Funzione"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Funzione</span> </div> </a> <button aria-controls="toc-Funzione-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Attiva/disattiva la sottosezione Funzione</span> </button> <ul id="toc-Funzione-sublist" class="vector-toc-list"> <li id="toc-Trasduzione_del_segnale" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Trasduzione_del_segnale"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Trasduzione del segnale</span> </div> </a> <ul id="toc-Trasduzione_del_segnale-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Rilevamento_e_riparazione_dei_danni" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Rilevamento_e_riparazione_dei_danni"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>Rilevamento e riparazione dei danni</span> </div> </a> <ul id="toc-Rilevamento_e_riparazione_dei_danni-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Storia" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Storia"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Storia</span> </div> </a> <ul id="toc-Storia-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Note" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Note"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Note</span> </div> </a> <ul id="toc-Note-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Bibliografia" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Bibliografia"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Bibliografia</span> </div> </a> <ul id="toc-Bibliografia-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Voci_correlate" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Voci_correlate"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Voci correlate</span> </div> </a> <ul id="toc-Voci_correlate-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Indice" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Mostra/Nascondi l'indice" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Mostra/Nascondi l'indice</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Assoplasma</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Vai a una voce in un'altra lingua. Disponibile in 9 lingue" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-9" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">9 lingue</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%B3%D9%8A%D8%AA%D9%88%D8%A8%D9%84%D8%A7%D8%B2%D9%85_%D8%A7%D9%84%D9%85%D8%AD%D9%88%D8%B1_%D8%A7%D9%84%D8%B9%D8%B5%D8%A8%D9%8A" title="سيتوبلازم المحور العصبي - arabo" lang="ar" hreflang="ar" data-title="سيتوبلازم المحور العصبي" data-language-autonym="العربية" data-language-local-name="arabo" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Axoplazma" title="Axoplazma - ceco" lang="cs" hreflang="cs" data-title="Axoplazma" data-language-autonym="Čeština" data-language-local-name="ceco" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Axoplasm" title="Axoplasm - inglese" lang="en" hreflang="en" data-title="Axoplasm" data-language-autonym="English" data-language-local-name="inglese" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Axoplasma" title="Axoplasma - spagnolo" lang="es" hreflang="es" data-title="Axoplasma" data-language-autonym="Español" data-language-local-name="spagnolo" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Axoplasma" title="Axoplasma - basco" lang="eu" hreflang="eu" data-title="Axoplasma" data-language-autonym="Euskara" data-language-local-name="basco" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Axoplasme" title="Axoplasme - francese" lang="fr" hreflang="fr" data-title="Axoplasme" data-language-autonym="Français" data-language-local-name="francese" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%90%D0%BA%D1%81%D0%BE%D0%BF%D0%BB%D0%B0%D0%B7%D0%BC%D0%B0" title="Аксоплазма - kazako" lang="kk" hreflang="kk" data-title="Аксоплазма" data-language-autonym="Қазақша" data-language-local-name="kazako" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Aksoplazma" title="Aksoplazma - polacco" lang="pl" hreflang="pl" data-title="Aksoplazma" data-language-autonym="Polski" data-language-local-name="polacco" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Axoplasma" title="Axoplasma - portoghese" lang="pt" hreflang="pt" data-title="Axoplasma" data-language-autonym="Português" data-language-local-name="portoghese" class="interlanguage-link-target"><span>Português</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q2874819#sitelinks-wikipedia" title="Modifica collegamenti interlinguistici" class="wbc-editpage">Modifica collegamenti</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespace"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Assoplasma" title="Vedi la voce [c]" accesskey="c"><span>Voce</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Discussione:Assoplasma" rel="discussion" title="Vedi le discussioni relative a questa pagina [t]" accesskey="t"><span>Discussione</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Cambia versione linguistica" > <label 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title="Modifica questa pagina [v]" accesskey="v"><span>Modifica</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Assoplasma&action=edit" title="Modifica il wikitesto di questa pagina [e]" accesskey="e"><span>Modifica wikitesto</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Assoplasma&action=history" title="Versioni precedenti di questa pagina [h]" accesskey="h"><span>Cronologia</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Strumenti pagine"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Strumenti" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Strumenti</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Strumenti</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">sposta nella barra laterale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">nascondi</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Altre opzioni" > <div class="vector-menu-heading"> Azioni </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Assoplasma"><span>Leggi</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Assoplasma&veaction=edit" title="Modifica questa pagina [v]" accesskey="v"><span>Modifica</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Assoplasma&action=edit" title="Modifica il wikitesto di questa pagina [e]" accesskey="e"><span>Modifica wikitesto</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Assoplasma&action=history"><span>Cronologia</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Generale </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Speciale:PuntanoQui/Assoplasma" title="Elenco di tutte le pagine che sono collegate a questa [j]" accesskey="j"><span>Puntano qui</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Speciale:ModificheCorrelate/Assoplasma" rel="nofollow" title="Elenco delle ultime modifiche alle pagine collegate a questa [k]" accesskey="k"><span>Modifiche correlate</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Speciale:PagineSpeciali" title="Elenco di tutte le pagine speciali [q]" accesskey="q"><span>Pagine speciali</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Assoplasma&oldid=124146417" title="Collegamento permanente a questa versione di questa pagina"><span>Link permanente</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Assoplasma&action=info" title="Ulteriori informazioni su questa pagina"><span>Informazioni pagina</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Speciale:Cita&page=Assoplasma&id=124146417&wpFormIdentifier=titleform" title="Informazioni su come citare questa pagina"><span>Cita questa voce</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Speciale:UrlShortener&url=https%3A%2F%2Fit.wikipedia.org%2Fwiki%2FAssoplasma"><span>Ottieni URL breve</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Speciale:QrCode&url=https%3A%2F%2Fit.wikipedia.org%2Fwiki%2FAssoplasma"><span>Scarica codice QR</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Stampa/esporta </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Speciale:Libro&bookcmd=book_creator&referer=Assoplasma"><span>Crea un libro</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Speciale:DownloadAsPdf&page=Assoplasma&action=show-download-screen"><span>Scarica come PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Assoplasma&printable=yes" title="Versione stampabile di questa pagina [p]" accesskey="p"><span>Versione stampabile</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> In altri progetti </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q2874819" title="Collegamento all'elemento connesso dell'archivio dati [g]" accesskey="g"><span>Elemento Wikidata</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Strumenti pagine"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Aspetto"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Aspetto</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">sposta nella barra laterale</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">nascondi</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Da Wikipedia, l'enciclopedia libera.</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="it" dir="ltr"><table class="infobox sinottico" summary="Tabella sinottica che riassume i principali dati del soggetto"><tbody><tr class="sinottico_testata"><th colspan="2" style="background:dimgray; color:white;">Assoplasma</th></tr><tr><th>Nome latino</th><td><i>axoplasma</i> </td></tr><tr><th><a href="/wiki/Apparato_(anatomia)" title="Apparato (anatomia)">Sistema</a></th><td>Sistema nervoso </td></tr><tr class="sinottico_divisione"><th colspan="2">Identificatori</th></tr><tr><th><a href="/w/index.php?title=Terminologia_Istologica&action=edit&redlink=1" class="new" title="Terminologia Istologica (la pagina non esiste)">TI</a></th><td>H2.00.06.1.00019 </td></tr><tr><td class="sinottico_piede2 noprint nomobile metadata" colspan="2"><a href="https://www.wikidata.org/wiki/Q2874819" class="extiw" title="d:Q2874819"><span title="Modifica i dati della voce Assoplasma su Wikidata">Modifica dati su Wikidata</span></a><b> ·</b> <a href="/wiki/Template:Anatomia/man" title="Template:Anatomia/man"><span title="Manuale del template Anatomia">Manuale</span></a></td></tr></tbody></table> <p>L'<b>assoplasma</b> è definito come il <a href="/wiki/Citoplasma" title="Citoplasma">citoplasma</a> all'interno dell'<a href="/wiki/Assone" title="Assone">assone</a> di un <a href="/wiki/Neurone" title="Neurone">neurone</a>. Assoni e <a href="/wiki/Dendrite_(biologia)" title="Dendrite (biologia)">dendriti</a> contengono circa il 99,6% del citoplasma delle cellule ed il 99,7% di esso è nell'assone<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>. L'assoplasma ha una diversa composizione rispetto a quella del corpo cellulare del neurone (soma) o nei dendriti. Nel trasporto assonale (noto anche come trasporto assoplasmico) i materiali vengono trasportati attraverso l'assoplasma da o verso il soma. </p><p>La <a href="/wiki/Resistenza_elettrica" title="Resistenza elettrica">resistenza elettrica</a> dell'assoplasma, chiamata resistenza assoplasmatica, è uno degli aspetti delle <a href="/wiki/Modello_a_cavo_di_un_assone" title="Modello a cavo di un assone">proprietà di cavo</a> dei neuroni, poiché determina la velocità a cui viaggia il <a href="/wiki/Potenziale_d%27azione" title="Potenziale d'azione">potenziale d'azione</a> attraverso un assone. Se l'assoplasma contiene molte molecole non conduttive, rallenterà la corsa del potenziale a causa del maggiore flusso di ioni attraverso l'assolemma (la membrana dell'assone). </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Struttura">Struttura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=1" title="Modifica la sezione Struttura" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=1" title="Edit section's source code: Struttura"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'assoplasma è composto da vari organelli ed elementi <a href="/wiki/Citoscheletro" title="Citoscheletro">citoscheletrici</a>, contiene un'alta concentrazione di <a href="/wiki/Mitocondrio" title="Mitocondrio">mitocondri</a> allungati, <a href="/wiki/Microfilamento" title="Microfilamento">microfilamenti</a> e <a href="/wiki/Microtubulo" title="Microtubulo">microtubuli</a>.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> L'assoplasma è privo di gran parte degli elementi cellulari (<a href="/wiki/Ribosoma" title="Ribosoma">ribosomi</a> e <a href="/wiki/Nucleo_cellulare" title="Nucleo cellulare">nucleo</a>) necessari per trascrivere e tradurre proteine complesse. Di conseguenza, la maggior parte degli enzimi e le grandi proteine vengono trasportate dal soma attraverso l'assoplasma. Il trasporto assonale avviene tramite sistemi di trasporto veloce o lento. Il trasporto veloce coinvolge il contenuto vescicolare (come gli <a href="/wiki/Organulo" title="Organulo">organelli</a>), che viene spostato lungo i microtubuli da proteine motorie a una velocità di 50-400 mm al giorno.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Il trasporto lento coinvolge le proteine solubili citosoliche e gli elementi citoscheletrici ad un ritmo di 0,02-0,1 mm al giorno. Il meccanismo del trasporto assonale lento rimane sconosciuto ma studi recenti hanno proposto che possa funzionare per mezzo di un'associazione transitoria con le vescicole del trasporto assonale veloce.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Il trasporto assonale è responsabile della presenza della maggior parte degli organelli e delle proteine complesse nell'assoplasma, studi recenti hanno dimostrato che nell'assoplasma avvengono anche traduzioni, che sono possibili grazie alla presenza di <a href="/wiki/RNA_messaggero" title="RNA messaggero">mRNA</a> e complessi proteici ribonucleari .<sup id="cite_ref-:0_5-0" class="reference"><a href="#cite_note-:0-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>I meccanismi di proliferazione cellulare e i potenziali elettrici sono influenzati dal sistema di trasporto assonale lento. Il sistema di trasporto assonale veloce modifica la velocità dei potenziali elettrici attraverso l'assone.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> Il sistema di trasporto assonale veloce è in grado di funzionare senza un assolemma, il che implica che il potenziale elettrico non influenza il trasporto di materiali attraverso l'assone.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Funzione">Funzione</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=2" title="Modifica la sezione Funzione" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=2" title="Edit section's source code: Funzione"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Trasduzione_del_segnale">Trasduzione del segnale</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=3" title="Modifica la sezione Trasduzione del segnale" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=3" title="Edit section's source code: Trasduzione del segnale"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'assoplasma ha la funzione di propagare il <a href="/wiki/Potenziale_d%27azione" title="Potenziale d'azione">potenziale d'azione</a> attraverso l'assone dei <a href="/wiki/Neurone" title="Neurone">neuroni</a>. La quantità di assoplasma dell'assone è importante perché il contenuto assoplasmatico determina la <a href="/wiki/Resistenza_elettrica" title="Resistenza elettrica">resistenza</a> dell'assone al cambiamento. Gli elementi citoscheletrici che compongono l'assoplasma, i filamenti neurali e i <a href="/wiki/Microtubulo" title="Microtubulo">microtubuli</a> costituiscono la struttura fondamentale per il trasporto assonale che consente ai <a href="/wiki/Neurotrasmettitore" title="Neurotrasmettitore">neurotrasmettitori</a> di raggiungere la <a href="/wiki/Sinapsi" title="Sinapsi">sinapsi</a>. Inoltre, l'assoplasma contiene le vescicole pre-sinaptiche contenenti il neurotrasmettitore che vengono rilasciate nella fessura sinaptica. </p> <div class="mw-heading mw-heading3"><h3 id="Rilevamento_e_riparazione_dei_danni">Rilevamento e riparazione dei danni</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=4" title="Modifica la sezione Rilevamento e riparazione dei danni" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=4" title="Edit section's source code: Rilevamento e riparazione dei danni"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'assoplasma contiene sia l'<a href="/wiki/RNA_messaggero" title="RNA messaggero">mRNA</a> che le proteine ribonucleari richieste per la <a href="/wiki/Sintesi_proteica" title="Sintesi proteica">sintesi proteica</a> assonale. La sintesi proteica assonale è parte integrante sia della rigenerazione neurale che delle risposte ai danni subiti dagli assoni.<sup id="cite_ref-:0_5-1" class="reference"><a href="#cite_note-:0-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> Quando un assone è danneggiato, la traslazione assonale e il trasporto assonale retrogrado sono necessari per trasmettere al soma il segnale che la cellula è danneggiata.<sup id="cite_ref-:0_5-2" class="reference"><a href="#cite_note-:0-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Storia">Storia</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=5" title="Modifica la sezione Storia" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=5" title="Edit section's source code: Storia"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L'assoplasma non era un obiettivo di ricerca neurologica fino all'avvento degli studi delle proprietà degli assoni giganti del <a href="/wiki/Loligo_vulgaris" title="Loligo vulgaris">calamaro</a>. Gli assoni in generale erano molto difficili da studiare a causa della loro struttura ristretta e della vicinanza alle <a href="/wiki/Cellula_della_glia" title="Cellula della glia">cellule gliali</a>.<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> Per risolvere questo problema vennero utilizzati gli assoni dei calamari, che hanno dimensioni relativamente grandi rispetto a quelli degli umani o di altri mammiferi.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Questi assoni furono studiati al fine di comprendere meglio il meccanismo del <a href="/wiki/Potenziale_d%27azione" title="Potenziale d'azione">potenziale di azione</a> e ben presto l'assoplasma fu identificato come parte fondamentale nel processo.<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> All'inizio si pensava che l'assoplasma fosse molto simile al <a href="/wiki/Citoplasma" title="Citoplasma">citoplasma</a>, ma poi si rese evidente la funzione di trasferimento di nutrienti e della conduzione del potenziale elettrico generato dai neuroni.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>Poiché risulta difficile isolare gli assoni dalla <a href="/wiki/Guaina_mielinica" title="Guaina mielinica">mielina</a> che li circonda,<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> l'assone gigante del calamaro è il fulcro di molti studi sull'assoplasma. </p><p>L'assoplasma è diventato un modello per lo studio di varie funzioni di segnalazione e funzioni cellulari nell'ambito della ricerca su malattie neurologiche come l'<a href="/wiki/Malattia_di_Alzheimer" title="Malattia di Alzheimer">Alzheimer</a>, e l'<a href="/wiki/Malattia_di_Huntington" title="Malattia di Huntington">Huntington</a>.<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> Il trasporto assonale rapido è cruciale in queste malattie vista la mancanza di materiali e sostanze nutritive che influenza la progressione dei disturbi neurologici. </p> <div class="mw-heading mw-heading2"><h2 id="Note">Note</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=6" title="Modifica la sezione Note" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=6" title="Edit section's source code: Note"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><a href="#cite_ref-1"><b>^</b></a> <span class="reference-text">Si veda <cite class="citation cita" style="font-style:normal"><a href="#CITEREFSabry">Sabry et al.</a></cite></span> </li> <li id="cite_note-2"><a href="#cite_ref-2"><b>^</b></a> <span class="reference-text"><cite class="citation libro" style="font-style:normal"> Hammond, C. (Constance), <a rel="nofollow" class="external text" href="https://www.worldcat.org/oclc/228568408"><span style="font-style:italic;">Cellular and molecular neurophysiology</span></a>, 3ª ed., Elsevier/Academic Press, 2008, p. 433, <a href="/wiki/ISBN" title="ISBN">ISBN</a> <a href="/wiki/Speciale:RicercaISBN/9780123741271" title="Speciale:RicercaISBN/9780123741271">9780123741271</a>, <a href="/wiki/Online_Computer_Library_Center" title="Online Computer Library Center">OCLC</a> <a rel="nofollow" class="external text" href="//www.worldcat.org/oclc/228568408">228568408</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-3"><a href="#cite_ref-3"><b>^</b></a> <span class="reference-text"><cite class="citation libro" style="font-style:normal"> Gerardo Morfini, Matthew R. Burns e David L. Stenoien, <a rel="nofollow" class="external text" href="https://www.researchgate.net/publication/284134007_Axonal_Transport"><span style="font-style:italic;">Basic Neurochemistry</span></a>, 31 dicembre 2012, pp. 146–164, <a href="/wiki/ISBN" title="ISBN">ISBN</a> <a href="/wiki/Speciale:RicercaISBN/9780123749475" title="Speciale:RicercaISBN/9780123749475">9780123749475</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-4"><a href="#cite_ref-4"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal"> Yong Tang, David Scott e Utpal Das, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782618/"><span style="font-style:italic;">Fast Vesicle Transport Is Required for the Slow Axonal Transport of Synapsin</span></a>, in <span style="font-style:italic;">The Journal of Neuroscience</span>, vol. 33, n. 39, 25 settembre 2013, pp. 15362–15375, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1523%2FJNEUROSCI.1148-13.2013">10.1523/JNEUROSCI.1148-13.2013</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-:0-5"><span class="mw-cite-backlink"><b>^</b> <sup><i><a href="#cite_ref-:0_5-0">a</a></i></sup> <sup><i><a href="#cite_ref-:0_5-1">b</a></i></sup> <sup><i><a href="#cite_ref-:0_5-2">c</a></i></sup></span> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal"> Michael Piper e Christine Holt, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682640/"><span style="font-style:italic;">RNA Translation in Axons</span></a>, in <span style="font-style:italic;">Annual review of cell and developmental biology</span>, vol. 20, 2004, pp. 505–523, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1146%2Fannurev.cellbio.20.010403.111746">10.1146/annurev.cellbio.20.010403.111746</a>, <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/3682640">3682640</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-6"><a href="#cite_ref-6"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) Scott T. Brady, <a rel="nofollow" class="external text" href="https://doi.org/10.1038/317073a0"><span style="font-style:italic;">A novel brain ATPase with properties expected for the fast axonal transport motor</span></a>, in <span style="font-style:italic;">Nature</span>, vol. 317, n. 6032, 1985-09, pp. 73–75, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2F317073a0">10.1038/317073a0</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-7"><a href="#cite_ref-7"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) S. T. Brady, R. J. Lasek e R. D. Allen, <a rel="nofollow" class="external text" href="http://science.sciencemag.org/content/218/4577/1129"><span style="font-style:italic;">Fast axonal transport in extruded axoplasm from squid giant axon</span></a>, in <span style="font-style:italic;">Science</span>, vol. 218, n. 4577, 10 dicembre 1982, pp. 1129–1131, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1126%2Fscience.6183745">10.1126/science.6183745</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-8"><a href="#cite_ref-8"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal"> D S Gilbert, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1348544/"><span style="font-style:italic;">Axoplasm chemical composition in Myxicola and solubility properties of its structural proteins.</span></a>, in <span style="font-style:italic;">The Journal of Physiology</span>, vol. 253, n. 1, 1975-12, pp. 303–319. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-9"><a href="#cite_ref-9"><b>^</b></a> <span class="reference-text"><cite class="citation libro" style="font-style:normal"> Young, J., <span style="font-style:italic;">What squids and octopuses tell us about brains and memories</span>, 1ª ed., American Museum of Natural History, 1997.</cite></span> </li> <li id="cite_note-10"><a href="#cite_ref-10"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) H. Burr Steinbach e Sol Spiegelman, <a rel="nofollow" class="external text" href="https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.1030220209"><span style="font-style:italic;">The sodium and potassium balance in squid nerve axoplasm</span></a>, in <span style="font-style:italic;">Journal of Cellular and Comparative Physiology</span>, vol. 22, n. 2, 1943-10, pp. 187–196, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2Fjcp.1030220209">10.1002/jcp.1030220209</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-11"><a href="#cite_ref-11"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal"> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119514/"><span style="font-style:italic;">GTP gamma S inhibits organelle transport along axonal microtubules</span></a>, in <span style="font-style:italic;">The Journal of Cell Biology</span>, vol. 120, n. 2, 2 gennaio 1993, pp. 467–476. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-12"><a href="#cite_ref-12"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) George H. DeVries, William T. Norton e Cedric S. Raine, <a rel="nofollow" class="external text" href="http://science.sciencemag.org/content/175/4028/1370"><span style="font-style:italic;">Axons:Isolation from Mammalian Central Nervous System</span></a>, in <span style="font-style:italic;">Science</span>, vol. 175, n. 4028, 24 marzo 1972, pp. 1370–1372, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1126%2Fscience.175.4028.1370">10.1126/science.175.4028.1370</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-13"><a href="#cite_ref-13"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) Nicholas M. Kanaan, Gerardo A. Morfini e Nichole E. LaPointe, <a rel="nofollow" class="external text" href="http://www.jneurosci.org/content/31/27/9858"><span style="font-style:italic;">Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases</span></a>, in <span style="font-style:italic;">Journal of Neuroscience</span>, vol. 31, n. 27, 6 luglio 2011, pp. 9858–9868, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1523%2FJNEUROSCI.0560-11.2011">10.1523/JNEUROSCI.0560-11.2011</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> <li id="cite_note-14"><a href="#cite_ref-14"><b>^</b></a> <span class="reference-text"><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) Gerardo A Morfini, Yi-Mei You e Sarah L Pollema, <a rel="nofollow" class="external text" href="https://doi.org/10.1038/nn.2346"><span style="font-style:italic;">Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin</span></a>, in <span style="font-style:italic;">Nature Neuroscience</span>, vol. 12, n. 7, 14 giugno 2009, pp. 864–871, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnn.2346">10.1038/nn.2346</a>. <small>URL consultato il 29 luglio 2018</small>.</cite></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Bibliografia">Bibliografia</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=7" title="Modifica la sezione Bibliografia" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=7" title="Edit section's source code: Bibliografia"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) <cite id="CITEREFSabry" class="citation pubblicazione" style="font-style:normal"> J. Sabry, O’Connor T. P., and Kirschner M. W., <a rel="nofollow" class="external text" href="https://oadoi.org/10.1016/0896-6273(95)90271-6"><span style="font-style:italic;">Axonal Transport of Tubulin in Tit Pioneer Neurons in Situ</span></a>, in <span style="font-style:italic;">Neuron, 14</span>, 1995, pp. 1247-1256, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0896-6273%2895%2990271-6">10.1016/0896-6273(95)90271-6</a>.</cite></li> <li>(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) <cite id="CITEREFCole" class="citation pubblicazione" style="font-style:normal"> K. S. anno = 1975 Cole, <a rel="nofollow" class="external text" href="http://jgp.rupress.org/cgi/reprint/66/2/133.pdf"><span style="font-style:italic;">Resistivity of Extruded Squid Axoplasm</span></a> (<span style="font-weight: bolder; font-size:80%"><abbr title="documento in formato PDF">PDF</abbr></span>), in <span style="font-style:italic;">The Journal of General Physiology, 66</span>, pp. I33-I38.</cite></li> <li>(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) <cite id="CITEREFThorn-Burg" class="citation pubblicazione" style="font-style:normal"> W. Thorn-Burg, E. De Robertis, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229719/pdf/475.pdf"><span style="font-style:italic;">Polarization and electron microscope study of frog nerve axoplasm</span></a> (<span style="font-weight: bolder; font-size:80%"><abbr title="documento in formato PDF">PDF</abbr></span>), in <span style="font-style:italic;"><a href="/wiki/The_Journal_of_Biophysical_and_Biochemical_Cytology" class="mw-redirect" title="The Journal of Biophysical and Biochemical Cytology">The Journal of Biophysical and Biochemical Cytology</a></span>, 1956, pp. 475-482.</cite></li></ul> <div class="mw-heading mw-heading2"><h2 id="Voci_correlate">Voci correlate</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Assoplasma&veaction=edit&section=8" title="Modifica la sezione Voci correlate" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Assoplasma&action=edit&section=8" title="Edit section's source code: Voci correlate"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Modello_a_cavo_di_un_assone" title="Modello a cavo di un assone">Modello a cavo di un assone</a></li></ul> <style data-mw-deduplicate="TemplateStyles:r141815314">.mw-parser-output .navbox{border:1px solid #aaa;clear:both;margin:auto;padding:2px;width:100%}.mw-parser-output .navbox th{padding-left:1em;padding-right:1em;text-align:center}.mw-parser-output .navbox>tbody>tr:first-child>th{background:#ccf;font-size:90%;width:100%;color:var(--color-base,black)}.mw-parser-output .navbox_navbar{float:left;margin:0;padding:0 10px 0 0;text-align:left;width:6em}.mw-parser-output .navbox_title{font-size:110%}.mw-parser-output .navbox_abovebelow{background:#ddf;font-size:90%;font-weight:normal}.mw-parser-output .navbox_group{background:#ddf;font-size:90%;padding:0 10px;white-space:nowrap}.mw-parser-output .navbox_list{font-size:90%;width:100%}.mw-parser-output .navbox_list a{white-space:nowrap}html:not(.vector-feature-night-mode-enabled) .mw-parser-output .navbox_odd{background:#fdfdfd;color:var(--color-base,black)}html:not(.vector-feature-night-mode-enabled) .mw-parser-output .navbox_even{background:#f7f7f7;color:var(--color-base,black)}.mw-parser-output .navbox a.mw-selflink{color:var(--color-base,black)}.mw-parser-output .navbox_center{text-align:center}.mw-parser-output .navbox .navbox_image{padding-left:7px;vertical-align:middle;width:0}.mw-parser-output .navbox+.navbox{margin-top:-1px}.mw-parser-output .navbox .mw-collapsible-toggle{font-weight:normal;text-align:right;width:7em}body.skin--responsive .mw-parser-output .navbox_image img{max-width:none!important}.mw-parser-output .subnavbox{margin:-3px;width:100%}.mw-parser-output .subnavbox_group{background:#e6e6ff;padding:0 10px}@media screen{html.skin-theme-clientpref-night .mw-parser-output .navbox>tbody>tr:first-child>th{background:var(--background-color-interactive)!important}html.skin-theme-clientpref-night .mw-parser-output .navbox th{color:var(--color-base)!important}html.skin-theme-clientpref-night .mw-parser-output .navbox_abovebelow,html.skin-theme-clientpref-night .mw-parser-output .navbox_group{background:var(--background-color-interactive-subtle)!important}html.skin-theme-clientpref-night .mw-parser-output .subnavbox_group{background:var(--background-color-neutral-subtle)!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbox>tbody>tr:first-child>th{background:var(--background-color-interactive)!important}html.skin-theme-clientpref-os .mw-parser-output .navbox th{color:var(--color-base)!important}html.skin-theme-clientpref-os .mw-parser-output .navbox_abovebelow,html.skin-theme-clientpref-os .mw-parser-output .navbox_group{background:var(--background-color-interactive-subtle)!important}html.skin-theme-clientpref-os .mw-parser-output .subnavbox_group{background:var(--background-color-neutral-subtle)!important}}</style><table class="navbox mw-collapsible mw-collapsed noprint metadata" id="navbox-Tessuto_nervoso"><tbody><tr><th colspan="3"><div class="navbox_navbar"><div class="noprint plainlinks" style="background-color:transparent; padding:0; font-size:xx-small; color:var(--color-base, #000000); white-space:nowrap;"><a href="/wiki/Template:Tessuto_nervoso" title="Template:Tessuto nervoso"><span title="Vai alla pagina del template">V</span></a> · <a href="/w/index.php?title=Discussioni_template:Tessuto_nervoso&action=edit&redlink=1" class="new" title="Discussioni template:Tessuto nervoso (la pagina non esiste)"><span title="Discuti del template">D</span></a> · <a class="external text" href="https://it.wikipedia.org/w/index.php?title=Template:Tessuto_nervoso&action=edit"><span title="Modifica il template. Usa l'anteprima prima di salvare">M</span></a></div></div><span class="navbox_title"><a href="/wiki/Istologia" title="Istologia">Istologia</a>: <a href="/wiki/Tessuto_nervoso" title="Tessuto nervoso">tessuto nervoso</a></span></th></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Neurone" title="Neurone">Neuroni</a> (<a href="/wiki/Sostanza_grigia" title="Sostanza grigia">sostanza grigia</a>)</th><td colspan="1" class="navbox_list navbox_odd" style="text-align:left;"><a href="/wiki/Soma_(medicina)" class="mw-redirect" title="Soma (medicina)">Soma</a> <b>·</b> <a href="/wiki/Assone" title="Assone">Assone</a> (<a href="/wiki/Cono_d%27emergenza" title="Cono d'emergenza">cono d'emergenza</a>, <a class="mw-selflink selflink">assoplasma</a>, <a href="/w/index.php?title=Assolemma&action=edit&redlink=1" class="new" title="Assolemma (la pagina non esiste)">assolemma</a>, <a href="/wiki/Neurofilamento" title="Neurofilamento">neurofibrilla/neurofilamento</a>) <b>·</b> <a href="/wiki/Dendrite_(biologia)" title="Dendrite (biologia)">Dendrite</a> (<a href="/w/index.php?title=Spina_denditrica&action=edit&redlink=1" class="new" title="Spina denditrica (la pagina non esiste)">spina denditrica</a>, <a href="/wiki/Dendrite_apicale" title="Dendrite apicale">dendrite apicale</a>, <a href="/w/index.php?title=Dendrite_basale&action=edit&redlink=1" class="new" title="Dendrite basale (la pagina non esiste)">dendrite basale</a>) <i>tipi</i>: <a href="/wiki/Cellula_piramidale" title="Cellula piramidale">Cellula piramidale</a> <b>·</b> <a href="/wiki/Cellula_di_Purkinje" class="mw-redirect" title="Cellula di Purkinje">Cellula di Purkinje</a></td><td rowspan="8" class="navbox_image"><figure class="mw-halign-right" typeof="mw:File"><a href="/wiki/File:Pyramidal_hippocampal_neuron_40x.jpg" class="mw-file-description" title="Tessuto nervoso"><img alt="Tessuto nervoso" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Pyramidal_hippocampal_neuron_40x.jpg/100px-Pyramidal_hippocampal_neuron_40x.jpg" decoding="async" width="100" height="76" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Pyramidal_hippocampal_neuron_40x.jpg/150px-Pyramidal_hippocampal_neuron_40x.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Pyramidal_hippocampal_neuron_40x.jpg/200px-Pyramidal_hippocampal_neuron_40x.jpg 2x" data-file-width="1344" data-file-height="1024" /></a><figcaption>Tessuto nervoso</figcaption></figure></td></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Fibre_afferenti" title="Fibre afferenti">Fibre afferenti</a></th><td colspan="1" class="navbox_list navbox_even" style="text-align:left;"><a href="/w/index.php?title=Fibre_afferenti_somatiche_generali&action=edit&redlink=1" class="new" title="Fibre afferenti somatiche generali (la pagina non esiste)">GSA</a> <b>·</b> <a href="/w/index.php?title=Fibre_afferenti_viscerali_generali&action=edit&redlink=1" class="new" title="Fibre afferenti viscerali generali (la pagina non esiste)">GVA</a> <b>·</b> <i>fibre</i> <a href="/w/index.php?title=A_alfa&action=edit&redlink=1" class="new" title="A alfa (la pagina non esiste)">Aα</a> (<a href="/wiki/Fusi_neuromuscolari" class="mw-redirect" title="Fusi neuromuscolari">Ia</a>, <a href="/wiki/Organo_tendineo_del_Golgi" title="Organo tendineo del Golgi">Ib</a>), <a href="/w/index.php?title=Fibra_sensoriale_tipo_II&action=edit&redlink=1" class="new" title="Fibra sensoriale tipo II (la pagina non esiste)">II o Aβ</a>, <a href="/w/index.php?title=Fibra_A_gamma&action=edit&redlink=1" class="new" title="Fibra A gamma (la pagina non esiste)">Aγ</a>, <a href="/w/index.php?title=Fibra_A_delta&action=edit&redlink=1" class="new" title="Fibra A delta (la pagina non esiste)">III o Aδ o del dolore veloce</a>, <a href="/w/index.php?title=Fibra_B&action=edit&redlink=1" class="new" title="Fibra B (la pagina non esiste)">B del sistema nervoso autonomo</a>, <a href="/w/index.php?title=Fibra_C&action=edit&redlink=1" class="new" title="Fibra C (la pagina non esiste)">IV o C o del dolore lento</a>)</td></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Fibre_efferenti" title="Fibre efferenti">Fibre efferenti</a></th><td colspan="1" class="navbox_list navbox_odd" style="text-align:left;"><a href="/w/index.php?title=Fibre_efferenti_somatiche_generali&action=edit&redlink=1" class="new" title="Fibre efferenti somatiche generali (la pagina non esiste)">GSE</a> <b>·</b> <a href="/w/index.php?title=Fibre_efferenti_viscerali_generali&action=edit&redlink=1" class="new" title="Fibre efferenti viscerali generali (la pagina non esiste)">GVE</a> <b>·</b> <a href="/w/index.php?title=Fibre_efferenti_somatiche_speciali&action=edit&redlink=1" class="new" title="Fibre efferenti somatiche speciali (la pagina non esiste)">SSE</a> <b>·</b> <a href="/wiki/Neurone_motorio_superiore" title="Neurone motorio superiore">Neurone motorio superiore</a> <b>·</b> <a href="/w/index.php?title=Neurone_motorio_inferiore&action=edit&redlink=1" class="new" title="Neurone motorio inferiore (la pagina non esiste)">Neurone motorio inferiore</a> (<a href="/w/index.php?title=Neurone_motorio_alfa&action=edit&redlink=1" class="new" title="Neurone motorio alfa (la pagina non esiste)">neurone motorio α</a>, <a href="/w/index.php?title=Neurone_motorio_gamma&action=edit&redlink=1" class="new" title="Neurone motorio gamma (la pagina non esiste)">neurone motorio γ</a>)</td></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Sinapsi" title="Sinapsi">Sinapsi</a></th><td colspan="1" class="navbox_list navbox_even" style="text-align:left;"><a href="/wiki/Neuropilo" title="Neuropilo">Neuropilo</a> <b>·</b> <a href="/wiki/Vescicola_sinaptica" class="mw-redirect" title="Vescicola sinaptica">Vescicola sinaptica</a> <b>·</b> <a href="/wiki/Giunzione_neuromuscolare" title="Giunzione neuromuscolare">Giunzione neuromuscolare</a> <b>·</b> <a href="/wiki/Sinapsi_elettrica" title="Sinapsi elettrica">Sinapsi elettrica</a> <b>·</b> <a href="/wiki/Interneurone" title="Interneurone">Interneurone</a> (<a href="/wiki/Cellula_di_Renshaw" class="mw-redirect" title="Cellula di Renshaw">Renshaw</a>)</td></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Recettore_sensoriale" class="mw-redirect" title="Recettore sensoriale">Recettori sensoriali</a></th><td colspan="1" class="navbox_list navbox_odd" style="text-align:left;"><a href="/w/index.php?title=Terminazione_libera&action=edit&redlink=1" class="new" title="Terminazione libera (la pagina non esiste)">Terminazione libera</a> <b>·</b> <a href="/wiki/Corpuscolo_di_Meissner" title="Corpuscolo di Meissner">Corpuscolo di Meissner</a> <b>·</b> <a href="/wiki/Cellula_di_Merkel" title="Cellula di Merkel">Cellula di Merkel</a> <b>·</b> <a href="/wiki/Fuso_neuromuscolare" title="Fuso neuromuscolare">Fuso neuromuscolare</a> <b>·</b> <a href="/wiki/Corpuscolo_di_Pacini" title="Corpuscolo di Pacini">Corpuscolo di Pacini</a> <b>·</b> <a href="/wiki/Corpuscolo_di_Ruffini" title="Corpuscolo di Ruffini">Corpuscolo di Ruffini</a> <b>·</b> <a href="/w/index.php?title=Neurone_sensoriale_olfattivo&action=edit&redlink=1" class="new" title="Neurone sensoriale olfattivo (la pagina non esiste)">Neurone sensoriale olfattivo</a> <b>·</b> <a href="/wiki/Fotorecettore" title="Fotorecettore">Fotorecettore</a> <b>·</b> <a href="/wiki/Cellula_ciliata" title="Cellula ciliata">Cellula ciliata</a> <b>·</b> <a href="/wiki/Papilla_gustativa" class="mw-redirect" title="Papilla gustativa">Papilla gustativa</a></td></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Cellula_della_glia" title="Cellula della glia">Cellule gliali</a></th><td colspan="1" class="navbox_list navbox_even" style="text-align:left;"><a href="/wiki/Astrocita" title="Astrocita">Astrocita</a> <b>·</b> <a href="/wiki/Oligodendrocita" title="Oligodendrocita">Oligodendrocita</a> <b>·</b> <a href="/wiki/Ependima" title="Ependima">Cellule ependimali</a> <b>·</b> <a href="/wiki/Microglia" title="Microglia">Microglia</a></td></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Mielina" class="mw-redirect" title="Mielina">Mielina</a> (<a href="/wiki/Sostanza_bianca" title="Sostanza bianca">sostanza bianca</a>)</th><td colspan="1" class="navbox_list navbox_odd" style="text-align:left;"><a href="/wiki/Cellula_di_Schwann" title="Cellula di Schwann">Cellula di Schwann</a> <b>·</b> <a href="/wiki/Oligodendrocita" title="Oligodendrocita">Oligodendrocita</a> <b>·</b> <a href="/wiki/Nodi_di_Ranvier" title="Nodi di Ranvier">Nodi di Ranvier</a> <b>·</b> <a href="/wiki/Incisure_di_Schmidt-Lanterman" title="Incisure di Schmidt-Lanterman">Incisure di Schmidt-Lanterman</a></td></tr><tr><th colspan="1" class="navbox_group" style="text-align:right;"><a href="/wiki/Tessuto_connettivo" title="Tessuto connettivo">Tessuti connettivi</a> correlati</th><td colspan="1" class="navbox_list navbox_even" style="text-align:left;"><a href="/wiki/Epinevrio" title="Epinevrio">Epinevrio</a> <b>·</b> <a href="/wiki/Perinevrio" title="Perinevrio">Perinevrio</a> <b>·</b> <a href="/wiki/Endonevrio" title="Endonevrio">Endonevrio</a> <b>·</b> <a href="/wiki/Meningi" title="Meningi">Meningi</a></td></tr><tr><th colspan="3" class="navbox_abovebelow">Gli alti tre tessuti: <a href="/wiki/Tessuto_epiteliale" title="Tessuto epiteliale">Tessuto epiteliale</a><b> ·</b> <a href="/wiki/Tessuto_connettivo" title="Tessuto connettivo">Tessuto connettivo</a><b> ·</b> <a href="/wiki/Tessuto_muscolare" title="Tessuto muscolare">Tessuto muscolare</a></th></tr></tbody></table> <div class="noprint" style="width:100%; padding: 3px 0; display: flex; flex-wrap: wrap; row-gap: 4px; column-gap: 8px; box-sizing: border-box;"><div 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